Search of human proteins with 50726996

Search of human proteins with 50726996

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|50726996 choline phosphotransferase 1 [Homo sapiens]
         (406 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|50726996 choline phosphotransferase 1 [Homo sapiens]               826   0.0  
gi|5174415 choline/ethanolaminephosphotransferase [Homo sapiens]      526   e-149
gi|56118223 choline/ethanolaminephosphotransferase [Homo sapiens]     526   e-149
gi|50083289 selenoprotein I [Homo sapiens]                            125   5e-29
gi|5453906 CDP-diacylglycerol-inositol 3-phosphatidyltransferase...    32   1.3  
gi|22296884 transmembrane protein 185A [Homo sapiens]                  30   5.1  
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa...    29   6.7  
gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa...    29   6.7  
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa...    29   6.7  
gi|239745999 PREDICTED: hypothetical protein [Homo sapiens]            29   8.7  
gi|7305525 low density lipoprotein-related protein 12 isoform a ...    29   8.7  

>gi|50726996 choline phosphotransferase 1 [Homo sapiens]
          Length = 406

 Score =  826 bits (2134), Expect = 0.0
 Identities = 406/406 (100%), Positives = 406/406 (100%)

Query: 1   MAAGAGAGSAPRWLRALSEPLSAAQLRRLEEHRYSAAGVSLLEPPLQLYWTWLLQWIPLW 60
           MAAGAGAGSAPRWLRALSEPLSAAQLRRLEEHRYSAAGVSLLEPPLQLYWTWLLQWIPLW
Sbjct: 1   MAAGAGAGSAPRWLRALSEPLSAAQLRRLEEHRYSAAGVSLLEPPLQLYWTWLLQWIPLW 60

Query: 61  MAPNSITLLGLAVNVVTTLVLISYCPTATEEAPYWTYLLCALGLFIYQSLDAIDGKQARR 120
           MAPNSITLLGLAVNVVTTLVLISYCPTATEEAPYWTYLLCALGLFIYQSLDAIDGKQARR
Sbjct: 61  MAPNSITLLGLAVNVVTTLVLISYCPTATEEAPYWTYLLCALGLFIYQSLDAIDGKQARR 120

Query: 121 TNSCSPLGELFDHGCDSLSTVFMAVGASIAARLGTYPDWFFFCSFIGMFVFYCAHWQTYV 180
           TNSCSPLGELFDHGCDSLSTVFMAVGASIAARLGTYPDWFFFCSFIGMFVFYCAHWQTYV
Sbjct: 121 TNSCSPLGELFDHGCDSLSTVFMAVGASIAARLGTYPDWFFFCSFIGMFVFYCAHWQTYV 180

Query: 181 SGMLRFGKVDVTEIQIALVIVFVLSAFGGATMWDYTIPILEIKLKILPVLGFLGGVIFSC 240
           SGMLRFGKVDVTEIQIALVIVFVLSAFGGATMWDYTIPILEIKLKILPVLGFLGGVIFSC
Sbjct: 181 SGMLRFGKVDVTEIQIALVIVFVLSAFGGATMWDYTIPILEIKLKILPVLGFLGGVIFSC 240

Query: 241 SNYFHVILHGGVGKNGSTIAGTSVLSPGLHIGLIIILAIMIYKKSATDVFEKHPCLYILM 300
           SNYFHVILHGGVGKNGSTIAGTSVLSPGLHIGLIIILAIMIYKKSATDVFEKHPCLYILM
Sbjct: 241 SNYFHVILHGGVGKNGSTIAGTSVLSPGLHIGLIIILAIMIYKKSATDVFEKHPCLYILM 300

Query: 301 FGCVFAKVSQKLVVAHMTKSELYLQDTVFLGPGLLFLDQYFNNFIDEYVVLWMAMVISSF 360
           FGCVFAKVSQKLVVAHMTKSELYLQDTVFLGPGLLFLDQYFNNFIDEYVVLWMAMVISSF
Sbjct: 301 FGCVFAKVSQKLVVAHMTKSELYLQDTVFLGPGLLFLDQYFNNFIDEYVVLWMAMVISSF 360

Query: 361 DMVIYFSALCLQISRHLHLNIFKTACHQAPEQVQVLSSKSHQNNMD 406
           DMVIYFSALCLQISRHLHLNIFKTACHQAPEQVQVLSSKSHQNNMD
Sbjct: 361 DMVIYFSALCLQISRHLHLNIFKTACHQAPEQVQVLSSKSHQNNMD 406


>gi|5174415 choline/ethanolaminephosphotransferase [Homo sapiens]
          Length = 416

 Score =  526 bits (1356), Expect = e-149
 Identities = 243/364 (66%), Positives = 296/364 (81%)

Query: 20  PLSAAQLRRLEEHRYSAAGVSLLEPPLQLYWTWLLQWIPLWMAPNSITLLGLAVNVVTTL 79
           PLS  QL+RLEEHRY +AG SLLEP +Q YW WL++ +P W+APN IT++GL++N+ TT+
Sbjct: 42  PLSRHQLKRLEEHRYQSAGRSLLEPLMQGYWEWLVRRVPSWIAPNLITIIGLSINICTTI 101

Query: 80  VLISYCPTATEEAPYWTYLLCALGLFIYQSLDAIDGKQARRTNSCSPLGELFDHGCDSLS 139
           +L+ YCPTATE+AP W Y+ CA GLFIYQSLDAIDGKQARRTNS SPLGELFDHGCDSLS
Sbjct: 102 LLVFYCPTATEQAPLWAYIACACGLFIYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLS 161

Query: 140 TVFMAVGASIAARLGTYPDWFFFCSFIGMFVFYCAHWQTYVSGMLRFGKVDVTEIQIALV 199
           TVF+ +G  IA +LGT PDW FFC F G F+FYCAHWQTYVSG LRFG +DVTE+QI ++
Sbjct: 162 TVFVVLGTCIAVQLGTNPDWMFFCCFAGTFMFYCAHWQTYVSGTLRFGIIDVTEVQIFII 221

Query: 200 IVFVLSAFGGATMWDYTIPILEIKLKILPVLGFLGGVIFSCSNYFHVILHGGVGKNGSTI 259
           I+ +L+  GG   W   IP+L I++KI P L  + G IFSC+NYF VI  GGVGKNGSTI
Sbjct: 222 IMHLLAVIGGPPFWQSMIPVLNIQMKIFPALCTVAGTIFSCTNYFRVIFTGGVGKNGSTI 281

Query: 260 AGTSVLSPGLHIGLIIILAIMIYKKSATDVFEKHPCLYILMFGCVFAKVSQKLVVAHMTK 319
           AGTSVLSP LHIG +I LA MIYKKSA  +FEKHPCLYIL FG V AK++ KLVVAHMTK
Sbjct: 282 AGTSVLSPFLHIGSVITLAAMIYKKSAVQLFEKHPCLYILTFGFVSAKITNKLVVAHMTK 341

Query: 320 SELYLQDTVFLGPGLLFLDQYFNNFIDEYVVLWMAMVISSFDMVIYFSALCLQISRHLHL 379
           SE++L DT F+GP LLFLDQYFN+FIDEY+VLW+A+V S FD++ Y  ++C QI+ HLH+
Sbjct: 342 SEMHLHDTAFIGPALLFLDQYFNSFIDEYIVLWIALVFSFFDLIRYCVSVCNQIASHLHI 401

Query: 380 NIFK 383
           ++F+
Sbjct: 402 HVFR 405


>gi|56118223 choline/ethanolaminephosphotransferase [Homo sapiens]
          Length = 416

 Score =  526 bits (1356), Expect = e-149
 Identities = 243/364 (66%), Positives = 296/364 (81%)

Query: 20  PLSAAQLRRLEEHRYSAAGVSLLEPPLQLYWTWLLQWIPLWMAPNSITLLGLAVNVVTTL 79
           PLS  QL+RLEEHRY +AG SLLEP +Q YW WL++ +P W+APN IT++GL++N+ TT+
Sbjct: 42  PLSRHQLKRLEEHRYQSAGRSLLEPLMQGYWEWLVRRVPSWIAPNLITIIGLSINICTTI 101

Query: 80  VLISYCPTATEEAPYWTYLLCALGLFIYQSLDAIDGKQARRTNSCSPLGELFDHGCDSLS 139
           +L+ YCPTATE+AP W Y+ CA GLFIYQSLDAIDGKQARRTNS SPLGELFDHGCDSLS
Sbjct: 102 LLVFYCPTATEQAPLWAYIACACGLFIYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLS 161

Query: 140 TVFMAVGASIAARLGTYPDWFFFCSFIGMFVFYCAHWQTYVSGMLRFGKVDVTEIQIALV 199
           TVF+ +G  IA +LGT PDW FFC F G F+FYCAHWQTYVSG LRFG +DVTE+QI ++
Sbjct: 162 TVFVVLGTCIAVQLGTNPDWMFFCCFAGTFMFYCAHWQTYVSGTLRFGIIDVTEVQIFII 221

Query: 200 IVFVLSAFGGATMWDYTIPILEIKLKILPVLGFLGGVIFSCSNYFHVILHGGVGKNGSTI 259
           I+ +L+  GG   W   IP+L I++KI P L  + G IFSC+NYF VI  GGVGKNGSTI
Sbjct: 222 IMHLLAVIGGPPFWQSMIPVLNIQMKIFPALCTVAGTIFSCTNYFRVIFTGGVGKNGSTI 281

Query: 260 AGTSVLSPGLHIGLIIILAIMIYKKSATDVFEKHPCLYILMFGCVFAKVSQKLVVAHMTK 319
           AGTSVLSP LHIG +I LA MIYKKSA  +FEKHPCLYIL FG V AK++ KLVVAHMTK
Sbjct: 282 AGTSVLSPFLHIGSVITLAAMIYKKSAVQLFEKHPCLYILTFGFVSAKITNKLVVAHMTK 341

Query: 320 SELYLQDTVFLGPGLLFLDQYFNNFIDEYVVLWMAMVISSFDMVIYFSALCLQISRHLHL 379
           SE++L DT F+GP LLFLDQYFN+FIDEY+VLW+A+V S FD++ Y  ++C QI+ HLH+
Sbjct: 342 SEMHLHDTAFIGPALLFLDQYFNSFIDEYIVLWIALVFSFFDLIRYCVSVCNQIASHLHI 401

Query: 380 NIFK 383
           ++F+
Sbjct: 402 HVFR 405


>gi|50083289 selenoprotein I [Homo sapiens]
          Length = 397

 Score =  125 bits (315), Expect = 5e-29
 Identities = 97/320 (30%), Positives = 152/320 (47%), Gaps = 27/320 (8%)

Query: 19  EPLSAAQLRRLEEHRYSAAGVSLLEPPLQLY-----WTWLLQWIPLWMAPNSITLLGLAV 73
           E +S  QL   ++++YSA   +    PL LY     W  +++  P W+APN IT  G  +
Sbjct: 5   EYVSPEQLAGFDKYKYSAVDTN----PLSLYVMHPFWNTIVKVFPTWLAPNLITFSGFLL 60

Query: 74  NVVTTLVLISYCPTATEEAPY------WTYLLCALGLFIYQSLDAIDGKQARRTNSCSPL 127
            V   L++  + P     AP       W +++  +  F+  +LD +DGKQARRTNS +PL
Sbjct: 61  VVFNFLLMAYFDPDFYASAPGHKHVPDWVWIVVGILNFVAYTLDGVDGKQARRTNSSTPL 120

Query: 128 GELFDHGCDSLSTVFMAVGA-SIAARLGTYPDWF--FFCSFIGMFVFYCAHWQTYVSGML 184
           GELFDHG DS S V+  V   SI  R  T    F  +   ++ +F F  +HW+ Y +G+L
Sbjct: 121 GELFDHGLDSWSCVYFVVTVYSIFGRGSTGVSVFVLYLLLWVVLFSFILSHWEKYNTGIL 180

Query: 185 RFGKVDVTEIQIALVIVFVLSAFGGATMW--DYTIPILEIKLKILPVLGFLGGVIFSCS- 241
            F        Q+ +  V++++A  G   W   +    L   L    ++G    V    S 
Sbjct: 181 -FLPWGYDISQVTISFVYIVTAVVGVEAWYEPFLFNFLYRDLFTAMIIGCALCVTLPMSL 239

Query: 242 -NYFHVILHGGVGKNGSTIAGTSVLSPGLHIGLIIILAIMIYKKSATDVFEKHPCLYILM 300
            N+F    +  +  N    A   + SP     L+ IL+      S +D+ E HP ++  M
Sbjct: 240 LNFFRSYKNNTLKLNSVYEAMVPLFSP----CLLFILSTAWILWSPSDILELHPRVFYFM 295

Query: 301 FGCVFAKVSQKLVVAHMTKS 320
            G  FA  + +L+V  M+ +
Sbjct: 296 VGTAFANSTCQLIVCQMSST 315


>gi|5453906 CDP-diacylglycerol-inositol 3-phosphatidyltransferase
           [Homo sapiens]
          Length = 213

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 33/118 (27%), Positives = 49/118 (41%), Gaps = 15/118 (12%)

Query: 68  LLGLAVNVVTTLVLISYCPTATEEAPYWTYLLCALGLFIYQSLDAIDGKQARRTNSCSPL 127
           L+G A  +V  ++   + P     A  + YLL  L       LDA DG  AR  N  +  
Sbjct: 13  LIGYA-RIVFAIISFYFMPCCPLTASSF-YLLSGL-------LDAFDGHAARALNQGTRF 63

Query: 128 GELFDHGCDSLSTVFMAVGASIAARLGTYPDWFFFCSFIGMFVFYCAHWQTYVSGMLR 185
           G + D   D  ST+ + V  ++      YP    F   I M +   +HW    S ++R
Sbjct: 64  GAMLDMLTDRCSTMCLLVNLAL-----LYPGATLFFQ-ISMSLDVASHWLHLHSSVVR 115


>gi|22296884 transmembrane protein 185A [Homo sapiens]
          Length = 350

 Score = 29.6 bits (65), Expect = 5.1
 Identities = 22/86 (25%), Positives = 38/86 (44%), Gaps = 9/86 (10%)

Query: 48  LYWTWLLQWIPLWMAPNSITLLGLAVNVVTTLVLISYCPTATEEAPY------WTYLLCA 101
           ++W WL+  +PLW+  + + L+ L   V + L L S    A +   +      W  ++  
Sbjct: 164 IHWPWLVVCVPLWILMSFLCLVVLYYIVWSVLFLRSMDVIAEQRRTHITMALSWMTIVVP 223

Query: 102 LGLFIYQSLDAIDGKQARRTNSCSPL 127
           L  F    +  +DG  A    SC P+
Sbjct: 224 LLTFEILLVHKLDGHNA---FSCIPI 246


>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
           sapiens]
          Length = 653

 Score = 29.3 bits (64), Expect = 6.7
 Identities = 20/79 (25%), Positives = 40/79 (50%), Gaps = 5/79 (6%)

Query: 223 KLKILPVLGFLGGVIFSCSNYFHVILHGGVGK----NGSTIAGTSVLSPGLHIGLIIILA 278
           ++K LPV+ +   + + C     V  + GV K    N +T+ G ++L P +   L I+  
Sbjct: 157 QVKSLPVVNY-NLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEG 215

Query: 279 IMIYKKSATDVFEKHPCLY 297
            ++ ++  + +  KH CL+
Sbjct: 216 TVVVQQLMSVMISKHDCLF 234


>gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo
           sapiens]
          Length = 655

 Score = 29.3 bits (64), Expect = 6.7
 Identities = 20/79 (25%), Positives = 40/79 (50%), Gaps = 5/79 (6%)

Query: 223 KLKILPVLGFLGGVIFSCSNYFHVILHGGVGK----NGSTIAGTSVLSPGLHIGLIIILA 278
           ++K LPV+ +   + + C     V  + GV K    N +T+ G ++L P +   L I+  
Sbjct: 159 QVKSLPVVNY-NLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEG 217

Query: 279 IMIYKKSATDVFEKHPCLY 297
            ++ ++  + +  KH CL+
Sbjct: 218 TVVVQQLMSVMISKHDCLF 236


>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
           sapiens]
          Length = 748

 Score = 29.3 bits (64), Expect = 6.7
 Identities = 20/79 (25%), Positives = 40/79 (50%), Gaps = 5/79 (6%)

Query: 223 KLKILPVLGFLGGVIFSCSNYFHVILHGGVGK----NGSTIAGTSVLSPGLHIGLIIILA 278
           ++K LPV+ +   + + C     V  + GV K    N +T+ G ++L P +   L I+  
Sbjct: 252 QVKSLPVVNY-NLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEG 310

Query: 279 IMIYKKSATDVFEKHPCLY 297
            ++ ++  + +  KH CL+
Sbjct: 311 TVVVQQLMSVMISKHDCLF 329


>gi|239745999 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 292

 Score = 28.9 bits (63), Expect = 8.7
 Identities = 12/37 (32%), Positives = 21/37 (56%), Gaps = 1/37 (2%)

Query: 269 LHIGLIIILAIMIYKKSATDVFEKHPCLYILMFGCVF 305
           +HI + + + + +Y     DV+  H CLYI M+ C +
Sbjct: 101 MHIYMYLYICMYMYMHVHMDVY-MHACLYICMYVCTY 136


>gi|7305525 low density lipoprotein-related protein 12 isoform a
           precursor [Homo sapiens]
          Length = 859

 Score = 28.9 bits (63), Expect = 8.7
 Identities = 12/46 (26%), Positives = 25/46 (54%)

Query: 352 WMAMVISSFDMVIYFSALCLQISRHLHLNIFKTACHQAPEQVQVLS 397
           W + ++  F   +Y +    + S ++H++   TAC + PEQ++  S
Sbjct: 13  WRSALLLLFLAGVYGNGALAEHSENVHISGVSTACGETPEQIRAPS 58


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.140    0.448 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,638,446
Number of Sequences: 37866
Number of extensions: 596040
Number of successful extensions: 1718
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1709
Number of HSP's gapped (non-prelim): 12
length of query: 406
length of database: 18,247,518
effective HSP length: 105
effective length of query: 301
effective length of database: 14,271,588
effective search space: 4295747988
effective search space used: 4295747988
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.