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Search of human proteins with 50726954
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50726954 presenilin stabilization factor-like isoform 1
[Homo sapiens]
(257 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50726954 presenilin stabilization factor-like isoform 1 [Homo... 512 e-145
gi|224548987 presenilin stabilization factor-like isoform 2 [Hom... 410 e-115
gi|117606357 anterior pharynx defective 1 homolog A isoform 2 [H... 300 6e-82
gi|117606362 anterior pharynx defective 1 homolog A isoform 1 [H... 299 1e-81
gi|217330618 Sec61 alpha form 2 isoform b [Homo sapiens] 30 2.7
gi|217330616 Sec61 alpha form 2 isoform c [Homo sapiens] 30 2.7
gi|14589847 Sec61 alpha form 2 isoform a [Homo sapiens] 30 2.7
gi|48717231 olfactory receptor, family 9, subfamily A, member 4 ... 30 2.7
gi|181337167 solute carrier family 7 (cationic amino acid transp... 29 3.5
gi|217330584 stimulated by retinoic acid gene 6 homolog isoform ... 28 6.0
gi|217330582 stimulated by retinoic acid gene 6 homolog isoform ... 28 6.0
gi|217330580 stimulated by retinoic acid gene 6 homolog isoform ... 28 6.0
gi|217330578 stimulated by retinoic acid gene 6 homolog isoform ... 28 6.0
gi|45433552 G protein-coupled receptor 133 [Homo sapiens] 28 7.9
>gi|50726954 presenilin stabilization factor-like isoform 1 [Homo
sapiens]
Length = 257
Score = 512 bits (1318), Expect = e-145
Identities = 257/257 (100%), Positives = 257/257 (100%)
Query: 1 MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII 60
MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII
Sbjct: 1 MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII 60
Query: 61 DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAPSMRLLAYVS 120
DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAPSMRLLAYVS
Sbjct: 61 DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAPSMRLLAYVS 120
Query: 121 GLGFGIMSGVFSFVNTLSDSLGPGTVGIHGDSPQFFLYSAFMTLVIILLHVFWGIVFFDG 180
GLGFGIMSGVFSFVNTLSDSLGPGTVGIHGDSPQFFLYSAFMTLVIILLHVFWGIVFFDG
Sbjct: 121 GLGFGIMSGVFSFVNTLSDSLGPGTVGIHGDSPQFFLYSAFMTLVIILLHVFWGIVFFDG 180
Query: 181 CEKKKWGILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLKL 240
CEKKKWGILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLKL
Sbjct: 181 CEKKKWGILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLKL 240
Query: 241 CLLCQDKNFLLYNQRSR 257
CLLCQDKNFLLYNQRSR
Sbjct: 241 CLLCQDKNFLLYNQRSR 257
>gi|224548987 presenilin stabilization factor-like isoform 2 [Homo
sapiens]
Length = 216
Score = 410 bits (1053), Expect = e-115
Identities = 216/257 (84%), Positives = 216/257 (84%), Gaps = 41/257 (15%)
Query: 1 MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII 60
MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII
Sbjct: 1 MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII 60
Query: 61 DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAPSMRLLAYVS 120
DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAPSMRLLAY
Sbjct: 61 DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAPSMRLLAY-- 118
Query: 121 GLGFGIMSGVFSFVNTLSDSLGPGTVGIHGDSPQFFLYSAFMTLVIILLHVFWGIVFFDG 180
AFMTLVIILLHVFWGIVFFDG
Sbjct: 119 ---------------------------------------AFMTLVIILLHVFWGIVFFDG 139
Query: 181 CEKKKWGILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLKL 240
CEKKKWGILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLKL
Sbjct: 140 CEKKKWGILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLKL 199
Query: 241 CLLCQDKNFLLYNQRSR 257
CLLCQDKNFLLYNQRSR
Sbjct: 200 CLLCQDKNFLLYNQRSR 216
>gi|117606357 anterior pharynx defective 1 homolog A isoform 2 [Homo
sapiens]
Length = 247
Score = 300 bits (769), Expect = 6e-82
Identities = 146/247 (59%), Positives = 189/247 (76%), Gaps = 1/247 (0%)
Query: 1 MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII 60
M AAVFFGC F+AFGPA AL++ T+A +PLR+I L+AGAFFWLVSLL++S+VWF+ +
Sbjct: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
Query: 61 DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAP-SMRLLAYV 119
D D Q LLIFGA VSV +QE+FRFAYYKLLKKA EGL S++ +P S+R +AYV
Sbjct: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
Query: 120 SGLGFGIMSGVFSFVNTLSDSLGPGTVGIHGDSPQFFLYSAFMTLVIILLHVFWGIVFFD 179
SGL FGI+SGVFS +N L+D+LGPG VGIHGDSP +FL SAF+T IILLH FWG+VFFD
Sbjct: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
Query: 180 GCEKKKWGILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLK 239
CE++++ L +V+ +HLL S TF++ +Y +L + + V MG WAF+ AGGS RS++
Sbjct: 181 ACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQ 240
Query: 240 LCLLCQD 246
LLC+D
Sbjct: 241 RSLLCKD 247
>gi|117606362 anterior pharynx defective 1 homolog A isoform 1 [Homo
sapiens]
Length = 265
Score = 299 bits (766), Expect = 1e-81
Identities = 147/257 (57%), Positives = 193/257 (75%), Gaps = 4/257 (1%)
Query: 1 MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII 60
M AAVFFGC F+AFGPA AL++ T+A +PLR+I L+AGAFFWLVSLL++S+VWF+ +
Sbjct: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
Query: 61 DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAP-SMRLLAYV 119
D D Q LLIFGA VSV +QE+FRFAYYKLLKKA EGL S++ +P S+R +AYV
Sbjct: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
Query: 120 SGLGFGIMSGVFSFVNTLSDSLGPGTVGIHGDSPQFFLYSAFMTLVIILLHVFWGIVFFD 179
SGL FGI+SGVFS +N L+D+LGPG VGIHGDSP +FL SAF+T IILLH FWG+VFFD
Sbjct: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
Query: 180 GCEKKKWGILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLK 239
CE++++ L +V+ +HLL S TF++ +Y +L + + V MG WAF+ AGGS RS++
Sbjct: 181 ACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQ 240
Query: 240 LCLLC---QDKNFLLYN 253
LLC +D ++Y+
Sbjct: 241 RSLLCRRQEDSRVMVYS 257
>gi|217330618 Sec61 alpha form 2 isoform b [Homo sapiens]
Length = 454
Score = 29.6 bits (65), Expect = 2.7
Identities = 17/53 (32%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Query: 192 VLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLKLCLLC 244
++L LVS IS + + F++ L+G WA ++ GG RS + LC
Sbjct: 269 IILQSALVSNLYVISQMLSVRFSGNFLVN-LLGQWADVSGGGPARSYPVGGLC 320
>gi|217330616 Sec61 alpha form 2 isoform c [Homo sapiens]
Length = 437
Score = 29.6 bits (65), Expect = 2.7
Identities = 17/53 (32%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Query: 192 VLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLKLCLLC 244
++L LVS IS + + F++ L+G WA ++ GG RS + LC
Sbjct: 291 IILQSALVSNLYVISQMLSVRFSGNFLVN-LLGQWADVSGGGPARSYPVGGLC 342
>gi|14589847 Sec61 alpha form 2 isoform a [Homo sapiens]
Length = 476
Score = 29.6 bits (65), Expect = 2.7
Identities = 17/53 (32%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Query: 192 VLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLKLCLLC 244
++L LVS IS + + F++ L+G WA ++ GG RS + LC
Sbjct: 291 IILQSALVSNLYVISQMLSVRFSGNFLVN-LLGQWADVSGGGPARSYPVGGLC 342
>gi|48717231 olfactory receptor, family 9, subfamily A, member 4
[Homo sapiens]
Length = 314
Score = 29.6 bits (65), Expect = 2.7
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 8/54 (14%)
Query: 2 TAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFM 55
T A F C I +G L LYV T+ A + W+VSL++S + F+
Sbjct: 240 TCASHFTCVVIGYGSCLFLYVKPKQTQ--------AADYNWVVSLMVSVVTPFL 285
>gi|181337167 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 14 [Homo sapiens]
Length = 771
Score = 29.3 bits (64), Expect = 3.5
Identities = 14/44 (31%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
Query: 164 LVIILLHVFWGIVFF--DGCEKKKWGILLIVLLTHLLVSAQTFI 205
L+ IL+ +F + F D ++ W +L+V+L LL+S F+
Sbjct: 571 LLFILMFIFCSFIIFGSDYISEQSWWAILLVVLMVLLISTLVFV 614
>gi|217330584 stimulated by retinoic acid gene 6 homolog isoform b
[Homo sapiens]
Length = 658
Score = 28.5 bits (62), Expect = 6.0
Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Query: 158 YSAFMTLVIILLHVFWGIVFFDGCEKKKWGILLIVLLTHLLVSAQTFISSY-YGINLASA 216
+SA+ T I L + I+FF G + +L+ VL L+ ++ SS+ + + LA A
Sbjct: 414 FSAYQTAFICLGLLVQQIIFFLGTTALAFLVLMPVLHGRNLLLFRSLESSWPFWLTLALA 473
Query: 217 FIILVLMGTWAFL 229
I+ + W FL
Sbjct: 474 VILQNMAAHWVFL 486
>gi|217330582 stimulated by retinoic acid gene 6 homolog isoform a
[Homo sapiens]
Length = 667
Score = 28.5 bits (62), Expect = 6.0
Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Query: 158 YSAFMTLVIILLHVFWGIVFFDGCEKKKWGILLIVLLTHLLVSAQTFISSY-YGINLASA 216
+SA+ T I L + I+FF G + +L+ VL L+ ++ SS+ + + LA A
Sbjct: 423 FSAYQTAFICLGLLVQQIIFFLGTTALAFLVLMPVLHGRNLLLFRSLESSWPFWLTLALA 482
Query: 217 FIILVLMGTWAFL 229
I+ + W FL
Sbjct: 483 VILQNMAAHWVFL 495
>gi|217330580 stimulated by retinoic acid gene 6 homolog isoform a
[Homo sapiens]
Length = 667
Score = 28.5 bits (62), Expect = 6.0
Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Query: 158 YSAFMTLVIILLHVFWGIVFFDGCEKKKWGILLIVLLTHLLVSAQTFISSY-YGINLASA 216
+SA+ T I L + I+FF G + +L+ VL L+ ++ SS+ + + LA A
Sbjct: 423 FSAYQTAFICLGLLVQQIIFFLGTTALAFLVLMPVLHGRNLLLFRSLESSWPFWLTLALA 482
Query: 217 FIILVLMGTWAFL 229
I+ + W FL
Sbjct: 483 VILQNMAAHWVFL 495
>gi|217330578 stimulated by retinoic acid gene 6 homolog isoform a
[Homo sapiens]
Length = 667
Score = 28.5 bits (62), Expect = 6.0
Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Query: 158 YSAFMTLVIILLHVFWGIVFFDGCEKKKWGILLIVLLTHLLVSAQTFISSY-YGINLASA 216
+SA+ T I L + I+FF G + +L+ VL L+ ++ SS+ + + LA A
Sbjct: 423 FSAYQTAFICLGLLVQQIIFFLGTTALAFLVLMPVLHGRNLLLFRSLESSWPFWLTLALA 482
Query: 217 FIILVLMGTWAFL 229
I+ + W FL
Sbjct: 483 VILQNMAAHWVFL 495
>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
Length = 874
Score = 28.1 bits (61), Expect = 7.9
Identities = 29/121 (23%), Positives = 52/121 (42%), Gaps = 18/121 (14%)
Query: 120 SGLGFGIMSGVFSFVNTLSDSLGPGTVG--IHGDSPQFFLYSAFMTLVIILLHVFWGIVF 177
+ L F ++ V + +S L PGT + +F SAF +++ LH++ ++
Sbjct: 606 ANLSFAVL--VAQVLLLISFRLEPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIK 663
Query: 178 FDGCEKKK--------WGILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFL 229
G E K WG L++ + L +F YG + + ++ L WAF+
Sbjct: 664 VFGSEDSKHRYYYGMGWGFPLLICIISL-----SFAMDSYGTS-NNCWLSLASGAIWAFV 717
Query: 230 A 230
A
Sbjct: 718 A 718
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.332 0.145 0.453
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,709,802
Number of Sequences: 37866
Number of extensions: 335798
Number of successful extensions: 954
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 946
Number of HSP's gapped (non-prelim): 16
length of query: 257
length of database: 18,247,518
effective HSP length: 100
effective length of query: 157
effective length of database: 14,460,918
effective search space: 2270364126
effective search space used: 2270364126
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.