Search of human proteins with 50592988

Search of human proteins with 50592988

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|50592988 ubiquinol-cytochrome c reductase core protein II
[Homo sapiens]
         (453 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|50592988 ubiquinol-cytochrome c reductase core protein II [Ho...   884   0.0  
gi|24308013 peptidase (mitochondrial processing) alpha [Homo sap...   139   5e-33
gi|94538354 mitochondrial processing peptidase beta subunit prec...   122   9e-28
gi|46593007 ubiquinol-cytochrome c reductase core protein I [Hom...   100   2e-21
gi|169194755 PREDICTED: hypothetical protein [Homo sapiens]            30   3.4  

>gi|50592988 ubiquinol-cytochrome c reductase core protein II [Homo
           sapiens]
          Length = 453

 Score =  884 bits (2283), Expect = 0.0
 Identities = 453/453 (100%), Positives = 453/453 (100%)

Query: 1   MKLLTRAGSFSRFYSLKVAPKVKATAAPAGAPPQPQDLEFTKLPNGLVIASLENYSPVSR 60
           MKLLTRAGSFSRFYSLKVAPKVKATAAPAGAPPQPQDLEFTKLPNGLVIASLENYSPVSR
Sbjct: 1   MKLLTRAGSFSRFYSLKVAPKVKATAAPAGAPPQPQDLEFTKLPNGLVIASLENYSPVSR 60

Query: 61  IGLFIKAGSRYEDFSNLGTTHLLRLTSSLTTKGASSFKITRGIEAVGGKLSVTATRENMA 120
           IGLFIKAGSRYEDFSNLGTTHLLRLTSSLTTKGASSFKITRGIEAVGGKLSVTATRENMA
Sbjct: 61  IGLFIKAGSRYEDFSNLGTTHLLRLTSSLTTKGASSFKITRGIEAVGGKLSVTATRENMA 120

Query: 121 YTVECLRGDVDILMEFLLNVTTAPEFRRWEVADLQPQLKIDKAVAFQNPQTHVIENLHAA 180
           YTVECLRGDVDILMEFLLNVTTAPEFRRWEVADLQPQLKIDKAVAFQNPQTHVIENLHAA
Sbjct: 121 YTVECLRGDVDILMEFLLNVTTAPEFRRWEVADLQPQLKIDKAVAFQNPQTHVIENLHAA 180

Query: 181 AYRNALANPLYCPDYRIGKVTSEELHYFVQNHFTSARMALIGLGVSHPVLKQVAEQFLNM 240
           AYRNALANPLYCPDYRIGKVTSEELHYFVQNHFTSARMALIGLGVSHPVLKQVAEQFLNM
Sbjct: 181 AYRNALANPLYCPDYRIGKVTSEELHYFVQNHFTSARMALIGLGVSHPVLKQVAEQFLNM 240

Query: 241 RGGLGLSGAKANYRGGEIREQNGDSLVHAAFVAESAVAGSAEANAFSVLQHVLGAGPHVK 300
           RGGLGLSGAKANYRGGEIREQNGDSLVHAAFVAESAVAGSAEANAFSVLQHVLGAGPHVK
Sbjct: 241 RGGLGLSGAKANYRGGEIREQNGDSLVHAAFVAESAVAGSAEANAFSVLQHVLGAGPHVK 300

Query: 301 RGSNTTSHLHQAVAKATQQPFDVSAFNASYSDSGLFGIYTISQATAAGDVIKAAYNQVKT 360
           RGSNTTSHLHQAVAKATQQPFDVSAFNASYSDSGLFGIYTISQATAAGDVIKAAYNQVKT
Sbjct: 301 RGSNTTSHLHQAVAKATQQPFDVSAFNASYSDSGLFGIYTISQATAAGDVIKAAYNQVKT 360

Query: 361 IAQGNLSNTDVQAAKNKLKAGYLMSVESSECFLEEVGSQALVAGSYMPPSTVLQQIDSVA 420
           IAQGNLSNTDVQAAKNKLKAGYLMSVESSECFLEEVGSQALVAGSYMPPSTVLQQIDSVA
Sbjct: 361 IAQGNLSNTDVQAAKNKLKAGYLMSVESSECFLEEVGSQALVAGSYMPPSTVLQQIDSVA 420

Query: 421 NADIINAAKKFVSGQKSMAASGNLGHTPFVDEL 453
           NADIINAAKKFVSGQKSMAASGNLGHTPFVDEL
Sbjct: 421 NADIINAAKKFVSGQKSMAASGNLGHTPFVDEL 453


>gi|24308013 peptidase (mitochondrial processing) alpha [Homo
           sapiens]
          Length = 525

 Score =  139 bits (350), Expect = 5e-33
 Identities = 116/479 (24%), Positives = 204/479 (42%), Gaps = 35/479 (7%)

Query: 9   SFSRFYSLKVAPKVKATAAPAGAPP---------QPQDLEFTKLPNGLVIASLENYSPVS 59
           ++ RF S    P +  ++   G P          +  + + T L NGL +AS   +    
Sbjct: 29  AYRRFSSGGAYPNIPLSSPLPGVPKPVFATVDGQEKFETKVTTLDNGLRVASQNKFGQFC 88

Query: 60  RIGLFIKAGSRYEDFSNLGTTHLL-RLTSSLTTKGASSFKITRGIEAVGGKLSVTATREN 118
            +G+ I +GSRYE     G  H L +L  S T +  S  +I   +E  GG      +R+ 
Sbjct: 89  TVGILINSGSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEILLTLEKHGGICDCQTSRDT 148

Query: 119 MAYTVECLRGDVDILMEFLLNVTTAPEFRRWEV--ADLQPQLKIDKAVAFQNPQTHVIEN 176
             Y V      +D ++  L +V   P     EV    +  Q +++      +P+  + E 
Sbjct: 149 TMYAVSADSKGLDTVVALLADVVLQPRLTDEEVEMTRMAVQFELEDLNLRPDPEPLLTEM 208

Query: 177 LHAAAYR-NALANPLYCPDYRIGKVTSEELHYFVQNHFTSARMALIGLGVSHPVLKQVAE 235
           +H AAYR N +    +CP   + K+  E LH +++N++T  RM L G+GV H  L   A 
Sbjct: 209 IHEAAYRENTVGLHRFCPTENVAKINREVLHSYLRNYYTPDRMVLAGVGVEHEHLVDCAR 268

Query: 236 QFL-------NMRGGLGLSGAKANYRGGEIREQNGDS-----------LVHAAFVAESAV 277
           ++L            + +  + A Y GG  + +   S           L H     ES  
Sbjct: 269 KYLLGVQPAWGSAEAVDIDRSVAQYTGGIAKLERDMSNVSLGPTPIPELTHIMVGLESCS 328

Query: 278 AGSAEANAFSVLQHVLGAGPHVKR---GSNTTSHLHQAVAKATQQPFDVSAFNASYSDSG 334
               +   F+VL  ++G G        G    S L+  V       ++ ++++ SY D+G
Sbjct: 329 FLEEDFIPFAVLNMMMGGGGSFSAGGPGKGMFSRLYLNVLNRHHWMYNATSYHHSYEDTG 388

Query: 335 LFGIYTISQATAAGDVIKAAYNQVKTIAQGNLSNTDVQAAKNKLKAGYLMSVESSECFLE 394
           L  I+  +      ++++    +   +  G +   +++ AK +L +  +M++ES     E
Sbjct: 389 LLCIHASADPRQVREMVEIITKEF-ILMGGTVDTVELERAKTQLTSMLMMNLESRPVIFE 447

Query: 395 EVGSQALVAGSYMPPSTVLQQIDSVANADIINAAKKFVSGQKSMAASGNLGHTPFVDEL 453
           +VG Q L   S   P  +   I +V   D+   A K + G+ ++AA G+L   P  + +
Sbjct: 448 DVGRQVLATRSRKLPHELCTLIRNVKPEDVKRVASKMLRGKPAVAALGDLTDLPTYEHI 506


>gi|94538354 mitochondrial processing peptidase beta subunit
           precursor [Homo sapiens]
          Length = 489

 Score =  122 bits (305), Expect = 9e-28
 Identities = 107/437 (24%), Positives = 189/437 (43%), Gaps = 11/437 (2%)

Query: 21  KVKATAAPAGAPPQPQDLEFTKLPNGLVIASLENYSPVSRIGLFIKAGSRYEDFSNLGTT 80
           ++++T A         +   T L +GL +AS ++      +GL+I AGSRYE+  N GT 
Sbjct: 41  RLRSTQAATQVVLNVPETRVTCLESGLRVASEDSGLSTCTVGLWIDAGSRYENEKNNGTA 100

Query: 81  HLLRLTSSLTTKGASSFKITRGIEAVGGKLSVTATRENMAYTVECLRGDVDILMEFLLNV 140
           H L   +   TK  S   +   IE +G  L+   +RE   Y  +    D+   +E L ++
Sbjct: 101 HFLEHMAFKGTKKRSQLDLELEIENMGAHLNAYTSREQTVYYAKAFSKDLPRAVEILADI 160

Query: 141 TTAPEFRRWEVADLQPQLKIDKAVAFQNPQTHVIENLHAAAYRN-ALANPLYCPDYRIGK 199
                    E+   +  +  +      N Q  V + LHA AY+N AL   +  P   I  
Sbjct: 161 IQNSTLGEAEIERERGVILREMQEVETNLQEVVFDYLHATAYQNTALGRTILGPTENIKS 220

Query: 200 VTSEELHYFVQNHFTSARMALIGL-GVSHPVLKQVAE----QFLNMRGGLGLSGAKANYR 254
           ++ ++L  ++  H+   R+ L    GVSH  L  +A+      L    G   +     + 
Sbjct: 221 ISRKDLVDYITTHYKGPRIVLAAAGGVSHDELLDLAKFHFGDSLCTHKGEIPALPPCKFT 280

Query: 255 GGEIREQNGD-SLVHAAFVAESAVAGSAEANAFSVLQHVLGAGPH-VKRGSNTTSHLHQA 312
           G EIR ++    L H A   E+      +     V   ++G        G N +S L Q 
Sbjct: 281 GSEIRVRDDKMPLAHLAIAVEAVGWAHPDTICLMVANTLIGNWDRSFGGGMNLSSKLAQL 340

Query: 313 VAKATQQPFDVSAFNASYSDSGLFGIYTISQATAAGDVIKAAYNQVKTIAQGNLSNTDVQ 372
                       +FN SY+D+GL+G+Y + +++   D++     +   +   +++ ++V 
Sbjct: 341 TCHG-NLCHSFQSFNTSYTDTGLWGLYMVCESSTVADMLHVVQKEWMRLCT-SVTESEVA 398

Query: 373 AAKNKLKAGYLMSVESSECFLEEVGSQALVAGSYMPPSTVLQQIDSVANADIINAAKKFV 432
            A+N LK   L+ ++ S    E++G Q L     +P   +  +ID+V    I     K++
Sbjct: 399 RARNLLKTNMLLQLDGSTPICEDIGRQMLCYNRRIPIPELEARIDAVNAETIREVCTKYI 458

Query: 433 SGQK-SMAASGNLGHTP 448
             +  ++AA G +   P
Sbjct: 459 YNRSPAIAAVGPIKQLP 475


>gi|46593007 ubiquinol-cytochrome c reductase core protein I [Homo
           sapiens]
          Length = 480

 Score =  100 bits (250), Expect = 2e-21
 Identities = 98/442 (22%), Positives = 190/442 (42%), Gaps = 18/442 (4%)

Query: 20  PKVKATAAPAGAPPQPQDLEFTKLPNGLVIASLENYSPVSRIGLFIKAGSRYEDFSNLGT 79
           P +++TA  A A     + + + L NGL +AS ++  P   +G++I  GSR+E   N G 
Sbjct: 30  PALRSTATFAQALQFVPETQVSLLDNGLRVASEQSSQPTCTVGVWIDVGSRFETEKNNGA 89

Query: 80  THLLRLTSSLTTKGASSFKITRGIEAVGGKLSVTATRENMAYTVECLRGDVDILMEFLLN 139
            + L   +   TK      + + +E++G  L+  +TRE+ AY ++ L  D+   +E L +
Sbjct: 90  GYFLEHLAFKGTKNRPGSALEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLGD 149

Query: 140 VTTAPEFRRWEVADLQPQLKIDKAVAFQNPQTHVIENLHAAAYRNA-LANPLYCPDYRIG 198
           +         ++   +  +  +      + +  V   LHA A++   LA  +  P   + 
Sbjct: 150 IVQNCSLEDSQIEKERDVILREMQENDASMRDVVFNYLHATAFQGTPLAQAVEGPSENVR 209

Query: 199 KVTSEELHYFVQNHFTSARMALIGL-GVSHPVLKQVAEQFLNMRGGLGLSGAK------- 250
           K++  +L  ++  H+ + RM L    GV H  L  +A++ L   GG+  + A+       
Sbjct: 210 KLSRADLTEYLSTHYKAPRMVLAAAGGVEHQQLLDLAQKHL---GGIPWTYAEDAVPTLT 266

Query: 251 -ANYRGGEIREQNGDSL--VHAAFVAESAVAGSAEANAFSVLQHVLGAGPHVKRGSNTTS 307
              + G EIR ++ D+L   H A   E     S +  A  V   ++G       G    S
Sbjct: 267 PCRFTGSEIRHRD-DALPFAHVAIAVEGPGWASPDNVALQVANAIIGHYDCTYGGGVHLS 325

Query: 308 HLHQAVAKATQQPFDVSAFNASYSDSGLFGIYTISQATAAGDVIKAAYNQVKTIAQGNLS 367
               + A A +       F+  Y+++GL G + +       D++     Q   +   + +
Sbjct: 326 SPLASGAVANKLCQSFQTFSICYAETGLLGAHFVCDRMKIDDMMFVLQGQWMRLCT-SAT 384

Query: 368 NTDVQAAKNKLKAGYLMSVESSECFLEEVGSQALVAGSYMPPSTVLQQIDSVANADIINA 427
            ++V   KN L+   +  ++ +    E++G   L  G  +P +    +I  V  + +   
Sbjct: 385 ESEVARGKNILRNALVSHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIAEVDASVVREI 444

Query: 428 AKKFVSGQ-KSMAASGNLGHTP 448
             K++  Q  ++A  G +   P
Sbjct: 445 CSKYIYDQCPAVAGYGPIEQLP 466


>gi|169194755 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 243

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 15/42 (35%), Positives = 20/42 (47%)

Query: 16 LKVAPKVKATAAPAGAPPQPQDLEFTKLPNGLVIASLENYSP 57
          L + P+ +  A P GAPP P    F      LV++ LE   P
Sbjct: 54 LSLQPQQRIPAPPPGAPPPPATRTFPTAQRPLVLSGLEQRYP 95


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.130    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,956,100
Number of Sequences: 37866
Number of extensions: 602775
Number of successful extensions: 1568
Number of sequences better than 10.0: 5
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1556
Number of HSP's gapped (non-prelim): 5
length of query: 453
length of database: 18,247,518
effective HSP length: 106
effective length of query: 347
effective length of database: 14,233,722
effective search space: 4939101534
effective search space used: 4939101534
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.