Search of human proteins with 49574491

Search of human proteins with 49574491

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|49574491 Na+/K+ -ATPase beta 2 subunit [Homo sapiens]
         (290 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|49574491 Na+/K+ -ATPase beta 2 subunit [Homo sapiens]              610   e-175
gi|4502281 Na+/K+ -ATPase beta 3 subunit [Homo sapiens]               247   8e-66
gi|215490093 ATPase, (Na+)/K+ transporting, beta 4 polypeptide i...   239   2e-63
gi|6912256 ATPase, (Na+)/K+ transporting, beta 4 polypeptide iso...   228   5e-60
gi|4557339 hydrogen/potassium-exchanging ATPase 4B [Homo sapiens]     226   2e-59
gi|4502277 Na+/K+ -ATPase beta 1 subunit isoform a [Homo sapiens]     211   5e-55
gi|49574489 Na+/K+ -ATPase beta 1 subunit isoform b [Homo sapiens]    211   6e-55
gi|62530386 fucose-1-phosphate guanyltransferase [Homo sapiens]        28   9.4  

>gi|49574491 Na+/K+ -ATPase beta 2 subunit [Homo sapiens]
          Length = 290

 Score =  610 bits (1572), Expect = e-175
 Identities = 290/290 (100%), Positives = 290/290 (100%)

Query: 1   MVIQKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMW 60
           MVIQKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMW
Sbjct: 1   MVIQKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMW 60

Query: 61  VMLQTVSDHTPKYQDRLATPGLMIRPKTENLDVIVNVSDTESWDQHVQKLNKFLEPYNDS 120
           VMLQTVSDHTPKYQDRLATPGLMIRPKTENLDVIVNVSDTESWDQHVQKLNKFLEPYNDS
Sbjct: 61  VMLQTVSDHTPKYQDRLATPGLMIRPKTENLDVIVNVSDTESWDQHVQKLNKFLEPYNDS 120

Query: 121 IQAQKNDVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQPCVFI 180
           IQAQKNDVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQPCVFI
Sbjct: 121 IQAQKNDVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQPCVFI 180

Query: 181 KMNRVINFYAGANQSMNVTCAGKRDEDAENLGNFVMFPANGNIDLMYFPYYGKKFHVNYT 240
           KMNRVINFYAGANQSMNVTCAGKRDEDAENLGNFVMFPANGNIDLMYFPYYGKKFHVNYT
Sbjct: 181 KMNRVINFYAGANQSMNVTCAGKRDEDAENLGNFVMFPANGNIDLMYFPYYGKKFHVNYT 240

Query: 241 QPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRVAFKLRINKT 290
           QPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRVAFKLRINKT
Sbjct: 241 QPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRVAFKLRINKT 290


>gi|4502281 Na+/K+ -ATPase beta 3 subunit [Homo sapiens]
          Length = 279

 Score =  247 bits (631), Expect = 8e-66
 Identities = 136/288 (47%), Positives = 184/288 (63%), Gaps = 21/288 (7%)

Query: 4   QKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMWVML 63
           + EKKS  Q + EWK F++NP T +F+GRT  SW  ILLFYLVFYGFL A+F+ TMWVML
Sbjct: 3   KNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVML 62

Query: 64  QTVSDHTPKYQDRLATPGLMIRPK-TENLDVIVNVSDTESWDQHVQKLNKFLEPYNDSIQ 122
           QT++D  PKY+D++ +PGLM+ PK    L+   + SD  S+  +++ L KFL+PY  +++
Sbjct: 63  QTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPY--TLE 120

Query: 123 AQKN-DVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQPCVFIK 181
            QKN  VC  G  +EQ     +     ACQF  + L  CSG+ D   +GYS G PC+ +K
Sbjct: 121 EQKNLTVCPDGALFEQKGPVYV-----ACQFPISLLQACSGMND-PDFGYSQGNPCILVK 174

Query: 182 MNRVINFYAGANQSMNVTCAGKRDEDAENLGNFVMFPANGNIDLMYFPYYGKKFHVNYTQ 241
           MNR+I           + C  K     E++ N  ++P NG IDL YFPYYGKK HV Y Q
Sbjct: 175 MNRIIGL--KPEGVPRIDCVSKN----EDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQ 228

Query: 242 PLVAVKFLNVTPN---VEVNVECRIN-AANIATDDERDKFAGRVAFKL 285
           PLVAV+ ++  PN    EV VEC+I+ +AN+ + D+RDKF GRV FK+
Sbjct: 229 PLVAVQ-VSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKI 275


>gi|215490093 ATPase, (Na+)/K+ transporting, beta 4 polypeptide
           isoform A [Homo sapiens]
          Length = 357

 Score =  239 bits (611), Expect = 2e-63
 Identities = 116/276 (42%), Positives = 169/276 (61%), Gaps = 4/276 (1%)

Query: 12  QVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMWVMLQTVSDHTP 71
           Q ++   E++W+P    F+ RTG SW+ ILL Y  FY  L A+ TL M+ +  T+S + P
Sbjct: 84  QKLQIMSEYLWDPERRMFLARTGQSWSLILLIYFFFYASLAAVITLCMYTLFLTISPYIP 143

Query: 72  KYQDRLATPGLMIRPKTENLDVIVNVSDTESWDQHVQKLNKFLEPYNDSIQAQKNDVCRP 131
            + +R+  PG+MIRP   +L+   NVS+ ++W  +V  LN FL+ YNDS+Q + N  C P
Sbjct: 144 TFTERVKPPGVMIRPFAHSLNFNFNVSEPDTWQHYVISLNGFLQGYNDSLQEEMNVDCPP 203

Query: 132 GRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQPCVFIKMNRVINFYAG 191
           G+Y+ Q  N   +  K+ACQF R+ L NCSG+ D T +GYSTGQPC+ +KMNR++ F   
Sbjct: 204 GQYFIQDGNE--DEDKKACQFKRSFLKNCSGLEDPT-FGYSTGQPCILLKMNRIVGFRPE 260

Query: 192 ANQSMNVTCAGKRDEDAENLGNFVMFPANGNIDLMYFPYYGKKFHVNYTQPLVAVKFLNV 251
               + V+C  +R  D  ++ +   +P + + DL Y+PYYGK  HVNYT PLVA+ F +V
Sbjct: 261 LGDPVKVSCKVQRG-DENDIRSISYYPESASFDLRYYPYYGKLTHVNYTSPLVAMHFTDV 319

Query: 252 TPNVEVNVECRINAANIATDDERDKFAGRVAFKLRI 287
             N  V V+C++    +  D   D+F GRV F L I
Sbjct: 320 VKNQAVPVQCQLKGKGVINDVINDRFVGRVIFTLNI 355


>gi|6912256 ATPase, (Na+)/K+ transporting, beta 4 polypeptide
           isoform B [Homo sapiens]
          Length = 353

 Score =  228 bits (581), Expect = 5e-60
 Identities = 114/276 (41%), Positives = 166/276 (60%), Gaps = 8/276 (2%)

Query: 12  QVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMWVMLQTVSDHTP 71
           Q ++   E++W+P    F+ RTG     ILL Y  FY  L A+ TL M+ +  T+S + P
Sbjct: 84  QKLQIMSEYLWDPERRMFLARTG----LILLIYFFFYASLAAVITLCMYTLFLTISPYIP 139

Query: 72  KYQDRLATPGLMIRPKTENLDVIVNVSDTESWDQHVQKLNKFLEPYNDSIQAQKNDVCRP 131
            + +R+  PG+MIRP   +L+   NVS+ ++W  +V  LN FL+ YNDS+Q + N  C P
Sbjct: 140 TFTERVKPPGVMIRPFAHSLNFNFNVSEPDTWQHYVISLNGFLQGYNDSLQEEMNVDCPP 199

Query: 132 GRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQPCVFIKMNRVINFYAG 191
           G+Y+ Q  N   +  K+ACQF R+ L NCSG+ D T +GYSTGQPC+ +KMNR++ F   
Sbjct: 200 GQYFIQDGNE--DEDKKACQFKRSFLKNCSGLEDPT-FGYSTGQPCILLKMNRIVGFRPE 256

Query: 192 ANQSMNVTCAGKRDEDAENLGNFVMFPANGNIDLMYFPYYGKKFHVNYTQPLVAVKFLNV 251
               + V+C  +R  D  ++ +   +P + + DL Y+PYYGK  HVNYT PLVA+ F +V
Sbjct: 257 LGDPVKVSCKVQRG-DENDIRSISYYPESASFDLRYYPYYGKLTHVNYTSPLVAMHFTDV 315

Query: 252 TPNVEVNVECRINAANIATDDERDKFAGRVAFKLRI 287
             N  V V+C++    +  D   D+F GRV F L I
Sbjct: 316 VKNQAVPVQCQLKGKGVINDVINDRFVGRVIFTLNI 351


>gi|4557339 hydrogen/potassium-exchanging ATPase 4B [Homo sapiens]
          Length = 291

 Score =  226 bits (576), Expect = 2e-59
 Identities = 113/295 (38%), Positives = 173/295 (58%), Gaps = 10/295 (3%)

Query: 1   MVIQKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMW 60
           M   +EKK+CGQ +EE++ + WNP T Q +GRT + W +I L+Y+ FY  +T +F L ++
Sbjct: 1   MAALQEKKTCGQRMEEFQRYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMTGLFALCLY 60

Query: 61  VMLQTVSDHTPKYQDRLATPGLMIRPKT---ENLDVIVNVSDTESWDQHVQKLNKFLEPY 117
           V++QTV  +TP YQD+L +PG+ +RP     + L+++ NVSD  +W    Q L+ FL  Y
Sbjct: 61  VLMQTVDPYTPDYQDQLRSPGVTLRPDVYGEKGLEIVYNVSDNRTWADLTQTLHAFLAGY 120

Query: 118 NDSIQAQKNDVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQPC 177
           + + Q    + C   +Y+ Q      N+ K +C+F    L NCSG+ D  ++G+  G+PC
Sbjct: 121 SPAAQEDSIN-CTSEQYFFQESFRAPNHTKFSCKFTADMLQNCSGLAD-PNFGFEEGKPC 178

Query: 178 VFIKMNRVINFYAGANQSMNVTCAGKRDEDAENLGNFVM---FPANGNIDLMYFPYYGKK 234
             IKMNR++ F      +  V CA    +    LG  +    +P NG   L YFPYYGKK
Sbjct: 179 FIIKMNRIVKFLPSNGSAPRVDCAFL--DQPRELGQPLQVKYYPPNGTFSLHYFPYYGKK 236

Query: 235 FHVNYTQPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRVAFKLRINK 289
              +Y+ PLVA K LN+  N EV + C++ A ++  ++  D + G+V FKL+I K
Sbjct: 237 AQPHYSNPLVAAKLLNIPRNAEVAIVCKVMAEHVTFNNPHDPYEGKVEFKLKIEK 291


>gi|4502277 Na+/K+ -ATPase beta 1 subunit isoform a [Homo sapiens]
          Length = 303

 Score =  211 bits (538), Expect = 5e-55
 Identities = 118/302 (39%), Positives = 170/302 (56%), Gaps = 29/302 (9%)

Query: 11  GQVVEE--WKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMWVMLQTVSD 68
           G+  EE  WK+F+WN    +F+GRTG SW  ILLFY++FYG L  +F  T+ VML T+S+
Sbjct: 4   GKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISE 63

Query: 69  HTPKYQDRLATPGLMIRPKTENLDVIVNVSDTESWDQHVQKLNKFLEPYNDSIQAQKNDV 128
             P YQDR+A PGL   P+ +  ++    +D +S++ +V  + +FLE Y DS  AQ++D+
Sbjct: 64  FKPTYQDRVAPPGLTQIPQIQKTEISFRPNDPKSYEAYVLNIVRFLEKYKDS--AQRDDM 121

Query: 129 C------RPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQPCVFIKM 182
                   P    E+ D       ++ C+F    LGNCSG+ D T YGY  G+PC+ IK+
Sbjct: 122 IFEDCGDVPSEPKERGDFNHERGERKVCRFKLEWLGNCSGLNDET-YGYKEGKPCIIIKL 180

Query: 183 NRVINF--YAGANQSMN-------------VTCAGKRDEDAENLGNFVMFPANGN--IDL 225
           NRV+ F      N+S+              V C GKRDED + +GN   F    +    L
Sbjct: 181 NRVLGFKPKPPKNESLETYPVMKYNPNVLPVQCTGKRDEDKDKVGNVEYFGLGNSPGFPL 240

Query: 226 MYFPYYGKKFHVNYTQPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRVAFKL 285
            Y+PYYGK     Y QPL+AV+F N+T + E+ +EC+    NI    E+D+F GR   K+
Sbjct: 241 QYYPYYGKLLQPKYLQPLLAVQFTNLTMDTEIRIECKAYGENIGY-SEKDRFQGRFDVKI 299

Query: 286 RI 287
            +
Sbjct: 300 EV 301


>gi|49574489 Na+/K+ -ATPase beta 1 subunit isoform b [Homo sapiens]
          Length = 301

 Score =  211 bits (537), Expect = 6e-55
 Identities = 118/301 (39%), Positives = 170/301 (56%), Gaps = 29/301 (9%)

Query: 11  GQVVEE--WKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMWVMLQTVSD 68
           G+  EE  WK+F+WN    +F+GRTG SW  ILLFY++FYG L  +F  T+ VML T+S+
Sbjct: 4   GKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISE 63

Query: 69  HTPKYQDRLATPGLMIRPKTENLDVIVNVSDTESWDQHVQKLNKFLEPYNDSIQAQKNDV 128
             P YQDR+A PGL   P+ +  ++    +D +S++ +V  + +FLE Y DS  AQ++D+
Sbjct: 64  FKPTYQDRVAPPGLTQIPQIQKTEISFRPNDPKSYEAYVLNIVRFLEKYKDS--AQRDDM 121

Query: 129 C------RPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQPCVFIKM 182
                   P    E+ D       ++ C+F    LGNCSG+ D T YGY  G+PC+ IK+
Sbjct: 122 IFEDCGDVPSEPKERGDFNHERGERKVCRFKLEWLGNCSGLNDET-YGYKEGKPCIIIKL 180

Query: 183 NRVINF--YAGANQSMN-------------VTCAGKRDEDAENLGNFVMFPANGN--IDL 225
           NRV+ F      N+S+              V C GKRDED + +GN   F    +    L
Sbjct: 181 NRVLGFKPKPPKNESLETYPVMKYNPNVLPVQCTGKRDEDKDKVGNVEYFGLGNSPGFPL 240

Query: 226 MYFPYYGKKFHVNYTQPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRVAFKL 285
            Y+PYYGK     Y QPL+AV+F N+T + E+ +EC+    NI    E+D+F GR   K+
Sbjct: 241 QYYPYYGKLLQPKYLQPLLAVQFTNLTMDTEIRIECKAYGENIGY-SEKDRFQGRFDVKI 299

Query: 286 R 286
           +
Sbjct: 300 K 300


>gi|62530386 fucose-1-phosphate guanyltransferase [Homo sapiens]
          Length = 594

 Score = 28.1 bits (61), Expect = 9.4
 Identities = 17/61 (27%), Positives = 27/61 (44%)

Query: 77  LATPGLMIRPKTENLDVIVNVSDTESWDQHVQKLNKFLEPYNDSIQAQKNDVCRPGRYYE 136
           LA P  +    T  + V+    D +  D   +  ++FL   +     Q N VCRPG + +
Sbjct: 191 LAHPSSLTIGTTHGVFVLDPFDDLKHRDLEYRSCHRFLHKPSIEKMYQFNAVCRPGNFCQ 250

Query: 137 Q 137
           Q
Sbjct: 251 Q 251


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,223,648
Number of Sequences: 37866
Number of extensions: 473525
Number of successful extensions: 897
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 865
Number of HSP's gapped (non-prelim): 8
length of query: 290
length of database: 18,247,518
effective HSP length: 101
effective length of query: 189
effective length of database: 14,423,052
effective search space: 2725956828
effective search space used: 2725956828
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.