Guide to the Human Genome
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Search of human proteins with 4826960

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4826960 glutaminyl-tRNA synthetase [Homo sapiens]
         (775 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4826960 glutaminyl-tRNA synthetase [Homo sapiens]                 1581   0.0  
gi|62241042 glutamyl-prolyl tRNA synthetase [Homo sapiens]            252   8e-67
gi|134288884 glutamyl-tRNA synthetase 2 [Homo sapiens]                 56   1e-07
gi|219689110 serine (or cysteine) proteinase inhibitor, clade B ...    34   0.45 
gi|4505595 serine (or cysteine) proteinase inhibitor, clade B (o...    34   0.45 
gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo sa...    31   5.0  
gi|216547519 interleukin-1 receptor-associated kinase 3 isoform ...    30   6.5  
gi|216547504 interleukin-1 receptor-associated kinase 3 isoform ...    30   6.5  

>gi|4826960 glutaminyl-tRNA synthetase [Homo sapiens]
          Length = 775

 Score = 1581 bits (4094), Expect = 0.0
 Identities = 775/775 (100%), Positives = 775/775 (100%)

Query: 1   MAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLA 60
           MAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLA
Sbjct: 1   MAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLA 60

Query: 61  SRLRDTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIVTPE 120
           SRLRDTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIVTPE
Sbjct: 61  SRLRDTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIVTPE 120

Query: 121 QIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADGKMIKNEVDMQVLHLLGPK 180
           QIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADGKMIKNEVDMQVLHLLGPK
Sbjct: 121 QIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADGKMIKNEVDMQVLHLLGPK 180

Query: 181 LEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGENYKT 240
           LEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGENYKT
Sbjct: 181 LEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGENYKT 240

Query: 241 PGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFL 300
           PGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFL
Sbjct: 241 PGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFL 300

Query: 301 RFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQ 360
           RFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQ
Sbjct: 301 RFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQ 360

Query: 361 RGEELKGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRV 420
           RGEELKGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRV
Sbjct: 361 RGEELKGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRV 420

Query: 421 KYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPV 480
           KYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPV
Sbjct: 421 KYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPV 480

Query: 481 QWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVG 540
           QWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVG
Sbjct: 481 QWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVG 540

Query: 541 VTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADET 600
           VTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADET
Sbjct: 541 VTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADET 600

Query: 601 KGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVES 660
           KGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVES
Sbjct: 601 KGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVES 660

Query: 661 LEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASL 720
           LEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASL
Sbjct: 661 LEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASL 720

Query: 721 HVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV 775
           HVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV
Sbjct: 721 HVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV 775


>gi|62241042 glutamyl-prolyl tRNA synthetase [Homo sapiens]
          Length = 1512

 Score =  252 bits (644), Expect = 8e-67
 Identities = 175/526 (33%), Positives = 254/526 (48%), Gaps = 38/526 (7%)

Query: 245 VTPHTMNLLKQHLEITG---GQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLR 301
           V P     + + +E+ G   G+V  RFPPE +G LHIGHAKA   N  Y     G   +R
Sbjct: 176 VAPEKKQDVGKFVELPGAEMGKVTVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMR 235

Query: 302 FDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQR 361
           FDDTNPEKE+  F   I + VA L   P + TY SD+F+ +  +A +LI+ G AYV    
Sbjct: 236 FDDTNPEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEKLIQEGKAYVDDTP 295

Query: 362 GEELKGHNT--LPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGK---MDPV 416
            E++K      + S  R  P+E++L ++E M+KG        LR K+ M        DP 
Sbjct: 296 AEQMKAEREQRIDSKHRKNPIEKNLQMWEEMKKGSQFGQSCCLRAKIDMSSNNGCMRDPT 355

Query: 417 AYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDV 476
            YR K  PH RTG+K+ +YPTYD+   + DSIE +TH+L T E+  R   ++W+  AL +
Sbjct: 356 LYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEALGI 415

Query: 477 YCPVQWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFC 536
             P  WEY RLNL+  V+SKRK+   V  G V  WDDPR  T+  + RRG   E +  F 
Sbjct: 416 RKPYIWEYSRLNLNNTVLSKRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFI 475

Query: 537 ARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFP 596
           A  G + +   ME   + A  + V++  APR +A+L+   VI  N P A+    +V   P
Sbjct: 476 AAQGSSRSVVNMEWDKIWAFNKKVIDPVAPRYVALLKK-EVIPVNVPEAQEEMKEVAKHP 534

Query: 597 ADETKGFHQVPFAPIVFIERTD---FKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKG 653
            +   G   V ++P VFIE  D   F E     F  + WG           + +  + K 
Sbjct: 535 KNPEVGLKPVWYSPKVFIEGADAETFSEGEMVTF--INWGN----------LNITKIHKN 582

Query: 654 PSGCVESLEVTCRRADAGEKPKAFIHWVSQ-------PLMCEVRLYERLFQHKNPEDPTE 706
             G + SL+      +   K    + W+++       P++C        ++H   +    
Sbjct: 583 ADGKIISLDAKLNLENKDYKKTTKVTWLAETTHALPIPVICVT------YEHLITKPVLG 636

Query: 707 VPGGFLSDLNLASLHVVDAALVDCSVALAKPFDKFQFERLGYFSVD 752
               F   +N  S H  +  L D  +   K  D  Q +R G+F  D
Sbjct: 637 KDEDFKQYVNKNSKH-EELMLGDPCLKDLKKGDIIQLQRRGFFICD 681


>gi|134288884 glutamyl-tRNA synthetase 2 [Homo sapiens]
          Length = 523

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 41/118 (34%), Positives = 54/118 (45%), Gaps = 12/118 (10%)

Query: 261 GGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICD 320
           G  VR RF P P G LH+G  +   +N+ +AK   G   LR +DT+  +        I D
Sbjct: 34  GVAVRVRFAPSPTGFLHLGGLRTALYNYIFAKKYQGSFILRLEDTDQTRVVPGAAENIED 93

Query: 321 MVAWLGYTPYKV--------TYASDYFDQLYAWAVE-LIRRGLAYVCH---QRGEELK 366
           M+ W G  P +          Y      +LYA A E L++ G AY C    QR E LK
Sbjct: 94  MLEWAGIPPDESPRRGGPAGPYQQSQRLELYAQATEALLKTGAAYPCFCSPQRLELLK 151


>gi|219689110 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 2 [Homo sapiens]
          Length = 415

 Score = 34.3 bits (77), Expect = 0.45
 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 2/85 (2%)

Query: 10  FTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLASRLRDTRRL 69
           FTS G  +Q  + +  ++ L AQ  +    + ++L S I+ +TG  L    ++L   +  
Sbjct: 76  FTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLFGEKSA 135

Query: 70  SFLVSYI--ASKKIHTEPQLSAALE 92
           SF   YI    K   +EPQ    LE
Sbjct: 136 SFREEYIRLCQKYYSSEPQAVDFLE 160


>gi|4505595 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 2 [Homo sapiens]
          Length = 415

 Score = 34.3 bits (77), Expect = 0.45
 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 2/85 (2%)

Query: 10  FTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLASRLRDTRRL 69
           FTS G  +Q  + +  ++ L AQ  +    + ++L S I+ +TG  L    ++L   +  
Sbjct: 76  FTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLFGEKSA 135

Query: 70  SFLVSYI--ASKKIHTEPQLSAALE 92
           SF   YI    K   +EPQ    LE
Sbjct: 136 SFREEYIRLCQKYYSSEPQAVDFLE 160


>gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo
           sapiens]
          Length = 419

 Score = 30.8 bits (68), Expect = 5.0
 Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 4/93 (4%)

Query: 10  FTSLGLSEQKARETLKN-SALSAQLREAATQAQQTLGSTIDKATGI-LLYGLASRLRDTR 67
           F  L    QKA ++L++      ++    +   Q  G +ID +    + Y  A  LRDT 
Sbjct: 326 FDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFAFELRDTG 385

Query: 68  RLSFLV--SYIASKKIHTEPQLSAALEYVRSHP 98
           R  FL+    I      T   L A +E+VR HP
Sbjct: 386 RYGFLLPARQILPTAEETWLGLKAIMEHVRDHP 418


>gi|216547519 interleukin-1 receptor-associated kinase 3 isoform a
           [Homo sapiens]
          Length = 596

 Score = 30.4 bits (67), Expect = 6.5
 Identities = 37/169 (21%), Positives = 64/169 (37%), Gaps = 26/169 (15%)

Query: 450 HITHSLCTKEFQARRSSYFWLCNALDVYCPVQW-EYGRLNLHYAVVSKRKILQLVATGAV 508
           H+ H  CT    +  S + W       Y P ++   G+L++   V S   ++  V TG  
Sbjct: 320 HLEHQSCTINMTSSSSKHLW-------YMPEEYIRQGKLSIKTDVYSFGIVIMEVLTGCR 372

Query: 509 RDWDDPRLFTLTALRR-----RGFP----------PEAINNFCARVGVTVAQTTMEPHLL 553
              DDP+   L  L R     RG            P    NF A++     +       L
Sbjct: 373 VVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAATRAKL 432

Query: 554 EACVRDVLN--DTAPRAMAVLESLRVIITNFPAAKSLDIQ-VPNFPADE 599
              + +VLN  ++   ++   E     + +F     L ++ VP+ P ++
Sbjct: 433 RPSMDEVLNTLESTQASLYFAEDPPTSLKSFRCPSPLFLENVPSIPVED 481


>gi|216547504 interleukin-1 receptor-associated kinase 3 isoform b
           [Homo sapiens]
          Length = 535

 Score = 30.4 bits (67), Expect = 6.5
 Identities = 37/169 (21%), Positives = 64/169 (37%), Gaps = 26/169 (15%)

Query: 450 HITHSLCTKEFQARRSSYFWLCNALDVYCPVQW-EYGRLNLHYAVVSKRKILQLVATGAV 508
           H+ H  CT    +  S + W       Y P ++   G+L++   V S   ++  V TG  
Sbjct: 259 HLEHQSCTINMTSSSSKHLW-------YMPEEYIRQGKLSIKTDVYSFGIVIMEVLTGCR 311

Query: 509 RDWDDPRLFTLTALRR-----RGFP----------PEAINNFCARVGVTVAQTTMEPHLL 553
              DDP+   L  L R     RG            P    NF A++     +       L
Sbjct: 312 VVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAATRAKL 371

Query: 554 EACVRDVLN--DTAPRAMAVLESLRVIITNFPAAKSLDIQ-VPNFPADE 599
              + +VLN  ++   ++   E     + +F     L ++ VP+ P ++
Sbjct: 372 RPSMDEVLNTLESTQASLYFAEDPPTSLKSFRCPSPLFLENVPSIPVED 420


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,374,270
Number of Sequences: 37866
Number of extensions: 1388619
Number of successful extensions: 2729
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 2721
Number of HSP's gapped (non-prelim): 8
length of query: 775
length of database: 18,247,518
effective HSP length: 110
effective length of query: 665
effective length of database: 14,082,258
effective search space: 9364701570
effective search space used: 9364701570
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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