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Search of human proteins with 4826954
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4826954 parathyroid hormone 2 receptor precursor [Homo
sapiens]
(550 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens] 1145 0.0
gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens] 507 e-144
gi|114205383 secretin receptor precursor [Homo sapiens] 292 5e-79
gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens] 282 5e-76
gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens] 264 2e-70
gi|29171759 adenylate cyclase activating polypeptide 1 (pituitar... 251 9e-67
gi|4758438 glucagon-like peptide 2 receptor precursor [Homo sapi... 243 4e-64
gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens] 239 6e-63
gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens] 236 3e-62
gi|4503947 glucagon receptor [Homo sapiens] 234 2e-61
gi|58530851 growth hormone releasing hormone receptor isoform a ... 233 4e-61
gi|4502547 calcitonin receptor [Homo sapiens] 220 3e-57
gi|32307159 corticotropin releasing hormone receptor 2 [Homo sap... 199 5e-51
gi|5031621 calcitonin receptor-like [Homo sapiens] 198 1e-50
gi|19923245 corticotropin releasing hormone receptor 1 isoform 2... 196 4e-50
gi|223717971 corticotropin releasing hormone receptor 1 isoform ... 181 2e-45
gi|223717978 corticotropin releasing hormone receptor 1 isoform ... 175 1e-43
gi|223717985 corticotropin releasing hormone receptor 1 isoform ... 169 6e-42
gi|58530853 growth hormone releasing hormone receptor isoform b ... 165 1e-40
gi|45433552 G protein-coupled receptor 133 [Homo sapiens] 83 6e-16
gi|133930786 egf-like module-containing mucin-like receptor 3 [H... 73 6e-13
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens] 73 8e-13
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens] 73 8e-13
gi|23397681 egf-like module containing, mucin-like, hormone rece... 72 1e-12
gi|23397693 egf-like module containing, mucin-like, hormone rece... 72 1e-12
gi|23397691 egf-like module containing, mucin-like, hormone rece... 72 1e-12
gi|23397689 egf-like module containing, mucin-like, hormone rece... 72 1e-12
gi|23397687 egf-like module containing, mucin-like, hormone rece... 72 1e-12
gi|23397685 egf-like module containing, mucin-like, hormone rece... 72 1e-12
gi|23397683 egf-like module containing, mucin-like, hormone rece... 72 1e-12
>gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]
Length = 550
Score = 1145 bits (2963), Expect = 0.0
Identities = 550/550 (100%), Positives = 550/550 (100%)
Query: 1 MAGLGASLHVWGWLMLGSCLLARAQLDSDGTITIEEQIVLVLKAKVQCELNITAQLQEGE 60
MAGLGASLHVWGWLMLGSCLLARAQLDSDGTITIEEQIVLVLKAKVQCELNITAQLQEGE
Sbjct: 1 MAGLGASLHVWGWLMLGSCLLARAQLDSDGTITIEEQIVLVLKAKVQCELNITAQLQEGE 60
Query: 61 GNCFPEWDGLICWPRGTVGKISAVPCPPYIYDFNHKGVAFRHCNPNGTWDFMHSLNKTWA 120
GNCFPEWDGLICWPRGTVGKISAVPCPPYIYDFNHKGVAFRHCNPNGTWDFMHSLNKTWA
Sbjct: 61 GNCFPEWDGLICWPRGTVGKISAVPCPPYIYDFNHKGVAFRHCNPNGTWDFMHSLNKTWA 120
Query: 121 NYSDCLRFLQPDISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIH 180
NYSDCLRFLQPDISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIH
Sbjct: 121 NYSDCLRFLQPDISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIH 180
Query: 181 MHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKIAV 240
MHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKIAV
Sbjct: 181 MHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKIAV 240
Query: 241 VMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAVARAT 300
VMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAVARAT
Sbjct: 241 VMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAVARAT 300
Query: 301 LADARCWELSAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTRKQYRK 360
LADARCWELSAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTRKQYRK
Sbjct: 301 LADARCWELSAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTRKQYRK 360
Query: 361 LAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFFVSIIYCYCNGEV 420
LAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFFVSIIYCYCNGEV
Sbjct: 361 LAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFFVSIIYCYCNGEV 420
Query: 421 QAEVKKMWSRWNLSVDWKRTPPCGSRRCGSVLTTVTHSTSSQSQVAASTRMVLISGKAAK 480
QAEVKKMWSRWNLSVDWKRTPPCGSRRCGSVLTTVTHSTSSQSQVAASTRMVLISGKAAK
Sbjct: 421 QAEVKKMWSRWNLSVDWKRTPPCGSRRCGSVLTTVTHSTSSQSQVAASTRMVLISGKAAK 480
Query: 481 IASRQPDSHITLPGYVWSNSEQDCLPHSFHEETKEDSGRQGDDILMEKPSRPMESNPDTE 540
IASRQPDSHITLPGYVWSNSEQDCLPHSFHEETKEDSGRQGDDILMEKPSRPMESNPDTE
Sbjct: 481 IASRQPDSHITLPGYVWSNSEQDCLPHSFHEETKEDSGRQGDDILMEKPSRPMESNPDTE 540
Query: 541 GCQGETEDVL 550
GCQGETEDVL
Sbjct: 541 GCQGETEDVL 550
>gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]
Length = 593
Score = 507 bits (1306), Expect = e-144
Identities = 256/477 (53%), Positives = 323/477 (67%), Gaps = 60/477 (12%)
Query: 22 ARAQLDSDGTITIEEQIVLVLKAKVQCELNITAQLQ------------------------ 57
A A +D+D +T EEQI L+ +A+ QCE + LQ
Sbjct: 22 AYALVDADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPASIMESDKGWTSASTSGKPRKD 81
Query: 58 --------EGEGN-------------CFPEWDGLICWPRGTVGKISAVPCPPYIYDFNHK 96
E E + C PEWD ++CWP G G++ AVPCP YIYDFNHK
Sbjct: 82 KASGKLYPESEEDKEAPTGSRYRGRPCLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHK 141
Query: 97 GVAFRHCNPNGTWDFMHSLNKTWANYSDCLRFLQPDISIGKQEFFERLYVMYTVGYSISF 156
G A+R C+ NG+W+ + N+TWANYS+C++FL + ++E F+RL ++YTVGYS+S
Sbjct: 142 GHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETR--EREVFDRLGMIYTVGYSVSL 199
Query: 157 GSLAVAILIIGYFRRLHCTRNYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESL--- 213
SL VA+LI+ YFRRLHCTRNYIHMHLF+SFMLRA SIFVKD V+++ + E E L
Sbjct: 200 ASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEE 259
Query: 214 ----IMQDDPQNSIEATSVDKSQYIGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVAF 269
I Q P + A Y GC++AV F+YFLATNYYWILVEGLYLH+LIF+AF
Sbjct: 260 ELRAIAQAPPPPATAAAG-----YAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAF 314
Query: 270 FSDTKYLWGFILIGWGFPAAFVAAWAVARATLADARCWELSAGDIKWIYQAPILAAIGLN 329
FS+ KYLWGF + GWG PA FVA W RATLA+ CW+LS+G+ KWI Q PILA+I LN
Sbjct: 315 FSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKKWIIQVPILASIVLN 374
Query: 330 FILFLNTVRVLATKIWETNAVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHS-FTG 388
FILF+N VRVLATK+ ETNA DTR+QYRKL KSTLVL+ +FGVHYIVF+ P++ +G
Sbjct: 375 FILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSG 434
Query: 389 LGWEIRMHCELFFNSFQGFFVSIIYCYCNGEVQAEVKKMWSRWNLSVDWKRTPPCGS 445
W+++MH E+ FNSFQGFFV+IIYC+CNGEVQAE+KK WSRW L++D+KR GS
Sbjct: 435 TLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKARSGS 491
>gi|114205383 secretin receptor precursor [Homo sapiens]
Length = 440
Score = 292 bits (748), Expect = 5e-79
Identities = 158/383 (41%), Positives = 223/383 (58%), Gaps = 52/383 (13%)
Query: 63 CFPEWDGLICWPRGTVGKISAVPCPPYIYDFNHK-GVAFRHCNPNGTWDFMHSLNKTWAN 121
C WD + CWP G++ V CP ++ + G FR+C +G W+
Sbjct: 66 CEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDG-----------WSE 114
Query: 122 YSDCLRFLQPDISIG----------KQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRR 171
F +P+++ G + + +L VMYTVGYS S L VA+ I+ FRR
Sbjct: 115 -----TFPRPNLACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRR 169
Query: 172 LHCTRNYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKS 231
LHCTRNYIHMHLFVSF+LRA S F+KD V+ + S + T D
Sbjct: 170 LHCTRNYIHMHLFVSFILRALSNFIKDAVLFS------------------SDDVTYCDAH 211
Query: 232 QYIGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFV 291
+ GCK+ +V+F Y + NY W+LVEGLYLH L+ ++FFS+ KYL GF+ GWG PA FV
Sbjct: 212 R-AGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFV 270
Query: 292 AAWAVARATLADARCWELSA-GDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAV 350
A WA+AR L D CW+++A I WI + P++ +I +NFILF+N +R+L K+
Sbjct: 271 ALWAIARHFLEDVGCWDINANASIWWIIRGPVILSILINFILFINILRILMRKLRTQETR 330
Query: 351 GHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFFVS 410
G++ Y++LA+STL+L+ +FG+HYIVF P EI++ EL SFQG V+
Sbjct: 331 GNEV-SHYKRLARSTLLLIPLFGIHYIVFAFSPED----AMEIQLFFELALGSFQGLVVA 385
Query: 411 IIYCYCNGEVQAEVKKMWSRWNL 433
++YC+ NGEVQ EV+K W +W+L
Sbjct: 386 VLYCFLNGEVQLEVQKKWQQWHL 408
>gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]
Length = 457
Score = 282 bits (722), Expect = 5e-76
Identities = 164/434 (37%), Positives = 235/434 (54%), Gaps = 45/434 (10%)
Query: 54 AQLQEGEGNCFPEWDGLICWPRGTVGKISAVPCPPYIYDFNH---KGVAFRHCNPNGTWD 110
AQL+ C WD L CWP G++ + CP F+ + V+ R C G W
Sbjct: 54 AQLENETIGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVS-RSCTDEG-WT 111
Query: 111 FMHSLNKTWANYSDCLRFLQPDISIGKQE--FFERLYVMYTVGYSISFGSLAVAILIIGY 168
+ Y S+ +Q+ F+ + YT+GY +S +L VA I+
Sbjct: 112 HLEP-----GPYPIACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSL 166
Query: 169 FRRLHCTRNYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSV 228
FR+LHCTRNYIHMHLF+SF+LRA ++F+KD + +S E+
Sbjct: 167 FRKLHCTRNYIHMHLFISFILRAAAVFIKDLALF------------------DSGESDQC 208
Query: 229 DKSQYIGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPA 288
+ +GCK A+V F Y + N++W+LVEGLYL+ L+ V+FFS+ KY WG+ILIGWG P+
Sbjct: 209 SEGS-VGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPS 267
Query: 289 AFVAAWAVARATLADARCWELSAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETN 348
F W +AR D CW+ + WI + PIL +I +NFILF+ +R+L K+ +
Sbjct: 268 TFTMVWTIARIHFEDYGCWDTINSSLWWIIKGPILTSILVNFILFICIIRILLQKLRPPD 327
Query: 349 AVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFF 408
D+ Y +LA+STL+L+ +FGVHYI+F P +F E++M EL SFQGF
Sbjct: 328 IRKSDS-SPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKP---EVKMVFELVVGSFQGFV 383
Query: 409 VSIIYCYCNGEVQAEVKKMWSRWNLS--VDWK---RTPPCGSR--RCG---SVLTTVTHS 458
V+I+YC+ NGEVQAE+++ W RW+L + W R P GS C S+LT V+
Sbjct: 384 VAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCSTQVSMLTRVSPG 443
Query: 459 TSSQSQVAASTRMV 472
S A +V
Sbjct: 444 ARRSSSFQAEVSLV 457
>gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]
Length = 438
Score = 264 bits (674), Expect = 2e-70
Identities = 142/390 (36%), Positives = 227/390 (58%), Gaps = 32/390 (8%)
Query: 41 VLKAKVQCELNITAQLQEGEGNCFPEWDGLICWPRGTVGKISAVPCPPYIYDFNHK-GVA 99
+ + + +C + +Q ++ + C WD + CW VG+ VPCP +F K G
Sbjct: 31 IQEEETKCAELLRSQTEKHKA-CSGVWDNITCWRPANVGETVTVPCPKVFSNFYSKAGNI 89
Query: 100 FRHCNPNGTWDFMHSLNKTWANYSDCLRFLQPDISIGKQEFFERLYVMYTVGYSISFGSL 159
++C +G W ++T+ ++ D + P+ K F+ + +YT+GYS+S SL
Sbjct: 90 SKNCTSDG-W------SETFPDFVDACGYSDPEDE-SKITFYILVKAIYTLGYSVSLMSL 141
Query: 160 AVAILIIGYFRRLHCTRNYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDP 219
A +I+ FR+LHCTRNYIH++LF+SF+LRA S+ VKD V+++ G +L D P
Sbjct: 142 ATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSG-----TLHCPDQP 196
Query: 220 QNSIEATSVDKSQYIGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGF 279
S ++GCK+++V Y + N++W+LVEGLYLH L+ VA + +
Sbjct: 197 -----------SSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLL-VAMLPPRRCFLAY 244
Query: 280 ILIGWGFPAAFVAAWAVARATLADARCWELSAGDIK-WIYQAPILAAIGLNFILFLNTVR 338
+LIGWG P + AW AR L D CW+ + + W+ + PIL +I +NF+LF++ +R
Sbjct: 245 LLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFISIIR 304
Query: 339 VLATKIWETNAVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCE 398
+L K+ + G+D + QY++LAKSTL+L+ +FGVHY+VF P S + + ++ E
Sbjct: 305 ILLQKLTSPDVGGND-QSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISS---KYQILFE 360
Query: 399 LFFNSFQGFFVSIIYCYCNGEVQAEVKKMW 428
L SFQG V+++YC+ N EVQ E+K+ W
Sbjct: 361 LCLGSFQGLVVAVLYCFLNSEVQCELKRKW 390
>gi|29171759 adenylate cyclase activating polypeptide 1 (pituitary)
receptor type I precursor [Homo sapiens]
Length = 468
Score = 251 bits (642), Expect = 9e-67
Identities = 143/436 (32%), Positives = 231/436 (52%), Gaps = 62/436 (14%)
Query: 63 CFPEWDGLICWPRGTVGKISAVPCPPYIYDFN------------------------HKGV 98
C WD + CW VG++ V CP FN GV
Sbjct: 54 CPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGV 113
Query: 99 AFRHCNPNGTWDFMHSLNKTWANYSDCLRFLQPDISIGKQEFFE-RLYVMYTVGYSISFG 157
R+C +G W ++ + +Y D F + + G Q+++ + +YTVGYS S
Sbjct: 114 VSRNCTEDG-W------SEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLV 166
Query: 158 SLAVAILIIGYFRRLHCTRNYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQD 217
+L A++I+ FR+LHCTRN+IHM+LFVSFMLRA S+F+KD +++A +
Sbjct: 167 TLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYA------------EQ 214
Query: 218 DPQNSIEATSVDKSQYIGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLW 277
D + +T + CK +V F Y + +NY+W+ +EGLYL L+ FF + +Y +
Sbjct: 215 DSNHCFIST-------VECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFY 267
Query: 278 GFILIGWGFPAAFVAAWAVARATLADARCWELS-AGDIKWIYQAPILAAIGLNFILFLNT 336
+ +IGWG P V WA R D CW+++ + + W+ + P++ +I +NF+LF+
Sbjct: 268 WYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGI 327
Query: 337 VRVLATKIWETNAVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMH 396
+ +L K+ + G+++ Y +LA+STL+L+ +FG+HY VF P + + R+
Sbjct: 328 IVILVQKLQSPDMGGNES-SIYLRLARSTLLLIPLFGIHYTVFAFSPEN---VSKRERLV 383
Query: 397 CELFFNSFQGFFVSIIYCYCNGEVQAEVKKMWSRWNL----SVDWKRTPP--CGSRRCGS 450
EL SFQGF V+++YC+ NGEVQAE+K+ W W + +VD+K P S G
Sbjct: 384 FELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGG 443
Query: 451 VLTTVTHSTSSQSQVA 466
++ +SSQ +++
Sbjct: 444 TQLSILSKSSSQIRMS 459
>gi|4758438 glucagon-like peptide 2 receptor precursor [Homo
sapiens]
Length = 553
Score = 243 bits (619), Expect = 4e-64
Identities = 135/376 (35%), Positives = 201/376 (53%), Gaps = 18/376 (4%)
Query: 63 CFPEWDGLICWPRGTVGKISAVPCPPYI--YDFNHKGVAFRHCNPNGTWDFMHSLNKTWA 120
C +D +CWP + G +S VPCP Y+ + G A+RHC GTW + + W
Sbjct: 96 CNGTFDQYVCWPHSSPGNVS-VPCPSYLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQ 154
Query: 121 NYSDCLRFLQPDISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIH 180
+ S+C ++ + L +MYTVGYS S SL +A+ ++ + R+LHCTRNYIH
Sbjct: 155 DDSECSENHSFKQNVDRYALLSTLQLMYTVGYSFSLISLFLALTLLLFLRKLHCTRNYIH 214
Query: 181 MHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKIAV 240
M+LF SF+LR ++ VKD V + + P N S C+
Sbjct: 215 MNLFASFILRTLAVLVKDVVFYNSYSKR----------PDNENGWMSYLSEMSTSCRSVQ 264
Query: 241 VMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAVARAT 300
V+ YF+ NY W+LVEGLYLH L+ + + ++L+GW FP FV W ARA
Sbjct: 265 VLLHYFVGANYLWLLVEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPVLFVVPWGFARAH 324
Query: 301 LADARCWELSAG-DIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTRKQYR 359
L + CW + I WI + P++ + +NF +FL +++L +K+ D + YR
Sbjct: 325 LENTGCWTTNGNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQMCFRDYK--YR 382
Query: 360 KLAKSTLVLVLVFGVHYIVFVCL-PHSFTGLGWEIRMHCELFFNSFQGFFVSIIYCYCNG 418
LAKSTLVL+ + GVH I+F + G IR+ +L +SF GF V++ Y + NG
Sbjct: 383 -LAKSTLVLIPLLGVHEILFSFITDDQVEGFAKLIRLFIQLTLSSFHGFLVALQYGFANG 441
Query: 419 EVQAEVKKMWSRWNLS 434
EV+AE++K W R+ L+
Sbjct: 442 EVKAELRKYWVRFLLA 457
>gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]
Length = 466
Score = 239 bits (609), Expect = 6e-63
Identities = 145/430 (33%), Positives = 220/430 (51%), Gaps = 40/430 (9%)
Query: 14 LMLGSCLLARAQLDSDGTITIEEQIVLVLKAKVQCELNITAQLQEGEGNCFPEWDGLICW 73
L L LL RA+ S G T E + + +C+ + A C +D +CW
Sbjct: 13 LSLCGLLLQRAETGSKGQ-TAGELYQRWERYRRECQETLAAAEPPSGLACNGSFDMYVCW 71
Query: 74 PRGTVGKISAVPCPPYIYDFNHKGVAF--RHCNPNGTWDFMHSLNKTWANYSDCLRFLQP 131
+ CP Y+ +H F R C +G W W +++ C +
Sbjct: 72 DYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGL-------WRDHTQCENPEKN 124
Query: 132 DISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHMHLFVSFMLRA 191
+ + ++ ERL VMYTVGYS+S +L +A+LI+ FRRLHCTRNYIH++LF SFMLRA
Sbjct: 125 EAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSFMLRA 184
Query: 192 TSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKIAVVMFIYFLATNY 251
+I +DR L+ + P +A ++ C+ A ++ Y + NY
Sbjct: 185 AAILSRDR-------------LLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANY 231
Query: 252 YWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAVARATLADARCWELS- 310
W+LVEG+YLH+L+ + S+ + ++L+GWG PA FV W + R + +CWE +
Sbjct: 232 TWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNE 291
Query: 311 AGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTRKQYRKLAKSTLVLVL 370
I WI + PIL I +NF++F+ + +L +K+ D R +LA+STL LV
Sbjct: 292 VKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYR---LRLARSTLTLVP 348
Query: 371 VFGVHYIVFVCLPHS-------FTGLGWEIRMHCELFFNSFQGFFVSIIYCYCNGEVQAE 423
+ GVH +VF + F LG+EI F +SFQGF VS++YC+ N EVQ+E
Sbjct: 349 LLGVHEVVFAPVTEEQARGALRFAKLGFEI------FLSSFQGFLVSVLYCFINKEVQSE 402
Query: 424 VKKMWSRWNL 433
+++ W L
Sbjct: 403 IRRGWHHCRL 412
>gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]
Length = 463
Score = 236 bits (603), Expect = 3e-62
Identities = 144/439 (32%), Positives = 229/439 (52%), Gaps = 23/439 (5%)
Query: 1 MAGLGASLHVWGWLMLGSCLLARAQLDSDG-TITIEEQIVLVLKAKVQCELNITAQLQEG 59
MAG L + L+LG ++ RA G T+++ E + + + QC+ ++T
Sbjct: 1 MAGAPGPLRL-ALLLLG--MVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPA 57
Query: 60 EGN-CFPEWDGLICWPRGTVGKISAVPCPPYIYDFNH--KGVAFRHCNPNGTWDFMHSLN 116
C +D CWP G G V CP Y+ + +G +R C G W + +
Sbjct: 58 TDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSS 117
Query: 117 KTWANYSDCLRFLQPDISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTR 176
W + S+C + + S +++ LY++YTVGY++SF +L +A I+ FR LHCTR
Sbjct: 118 LPWRDLSECEESKRGERSSPEEQLLF-LYIIYTVGYALSFSALVIASAILLGFRHLHCTR 176
Query: 177 NYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGC 236
NYIH++LF SF+LRA S+F+KD +K + S Q + + + + C
Sbjct: 177 NYIHLNLFASFILRALSVFIKD------AALKWMYSTAAQQHQWDGL----LSYQDSLSC 226
Query: 237 KIAVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAV 296
++ ++ Y +A NYYW+LVEG+YL+ L+ + S+ ++ IGWG P FV W +
Sbjct: 227 RLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGI 286
Query: 297 ARATLADARCWELSAGDIKW-IYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTR 355
+ D CW ++ W I + PIL AIG+NF++F+ + ++ +K+ D +
Sbjct: 287 VKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIK 346
Query: 356 KQYRKLAKSTLVLVLVFGVHYIVFV-CLPHSFTGLGWEIRMHCELFFNSFQGFFVSIIYC 414
+LAKSTL L+ + G H ++F + G I++ EL F SFQG V+I+YC
Sbjct: 347 ---CRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYC 403
Query: 415 YCNGEVQAEVKKMWSRWNL 433
+ N EVQ E +K W RW L
Sbjct: 404 FVNNEVQLEFRKSWERWRL 422
>gi|4503947 glucagon receptor [Homo sapiens]
Length = 477
Score = 234 bits (597), Expect = 2e-61
Identities = 138/412 (33%), Positives = 214/412 (51%), Gaps = 23/412 (5%)
Query: 47 QCELNITAQLQEGEGNCFPEWDGLICWPRGTVGKISAVPCP---PYIYDFNHKGVAFRHC 103
QC N++ E C +D CWP + + CP P+ + H+ V F+ C
Sbjct: 42 QCHHNLSLLPPPTELVCNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFV-FKRC 100
Query: 104 NPNGTWDFMHSLNKTWANYSDCLRFLQPDISIGKQ--EFFERLYVMYTVGYSISFGSLAV 161
P+G W + W + S C + +I + K+ + + VMYTVGYS+S G+L +
Sbjct: 101 GPDGQW-VRGPRGQPWRDASQC-QMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLL 158
Query: 162 AILIIGYFRRLHCTRNYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQN 221
A+ I+G +LHCTRN IH +LF SF+L+A+S+ V D ++ K + L +
Sbjct: 159 ALAILGGLSKLHCTRNAIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSV------ 212
Query: 222 SIEATSVDKSQYIGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFIL 281
+T + GC++A V Y + NY W+LVEGLYLHNL+ +A + + ++
Sbjct: 213 ---STWLSDGAVAGCRVAAVFMQYGIVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLG 269
Query: 282 IGWGFPAAFVAAWAVARATLADARCWELSAG-DIKWIYQAPILAAIGLNFILFLNTVRVL 340
IGWG P FV WAV + + +CW + WI + P+ AI +NF +F+ V++L
Sbjct: 270 IGWGAPMLFVVPWAVVKCLFENVQCWTSNDNMGFWWILRFPVFLAILINFFIFVRIVQLL 329
Query: 341 ATKIWETNAVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFT-GLGWEIRMHCEL 399
K+ H T ++R LAKSTL L+ + GVH +VF + G ++ +L
Sbjct: 330 VAKLRARQM--HHTDYKFR-LAKSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDL 386
Query: 400 FFNSFQGFFVSIIYCYCNGEVQAEVKKMWSRWNL-SVDWKRTPPCGSRRCGS 450
F +SFQG V+++YC+ N EVQ+E+++ W RW L V W+ R S
Sbjct: 387 FLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRLGKVLWEERNTSNHRASSS 438
>gi|58530851 growth hormone releasing hormone receptor isoform a
precursor [Homo sapiens]
Length = 423
Score = 233 bits (593), Expect = 4e-61
Identities = 139/406 (34%), Positives = 205/406 (50%), Gaps = 51/406 (12%)
Query: 63 CFPEWDGLICWPRGTVGKISAVPCPPYIYDFNHK-GVAFRHCNPNGTWDFMHSLNKTWAN 121
C WDGL+CWP G+ +PCP + F+ + G R C G W+
Sbjct: 55 CPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITG-----------WSE 103
Query: 122 YSDCLRFLQP---DISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNY 178
P ++ ++ +F + ++YTVG+SIS +L VAI I+ RRLHC RNY
Sbjct: 104 PFPPYPVACPVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNY 163
Query: 179 IHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKI 238
+H LF +F+L+A ++F+KD +L DD + +T + CK+
Sbjct: 164 VHTQLFTTFILKAGAVFLKD------------AALFHSDDTDHCSFST-------VLCKV 204
Query: 239 AVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAVAR 298
+V + TN+ W+L E +YL+ L+ S + W +L GWG P F W +
Sbjct: 205 SVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCK 264
Query: 299 ATLADARCWEL-SAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTRKQ 357
D CW+L WI + PI+ ++G+NF LFLN +R+L K+ H T+ Q
Sbjct: 265 LAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLH-TQSQ 323
Query: 358 YRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFFVSIIYCYCN 417
Y +L+KSTL L+ +FG+HYI+F LP + GLG IR+ EL SFQGF V+I+YC+ N
Sbjct: 324 YWRLSKSTLFLIPLFGIHYIIFNFLPDN-AGLG--IRLPLELGLGSFQGFIVAILYCFLN 380
Query: 418 GEVQAEVKKMW--------SRWNLSVDWKRTPPCGSRRCGSVLTTV 455
EV+ E+ + W W W TP SR VLT++
Sbjct: 381 QEVRTEISRKWHGHDPELLPAWRTRAKW-TTP---SRSAAKVLTSM 422
>gi|4502547 calcitonin receptor [Homo sapiens]
Length = 474
Score = 220 bits (560), Expect = 3e-57
Identities = 131/398 (32%), Positives = 204/398 (51%), Gaps = 38/398 (9%)
Query: 58 EGEGN-CFPEWDGLICWPRGTVGKISAVPCPPYIYDFNHKGVAFRHCNPNGTWDFMHSLN 116
+GEG C WDG +CW G +S CP Y DF+ ++C+ G W N
Sbjct: 66 QGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFKHPENN 125
Query: 117 KTWANYSDCLRFLQPDISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTR 176
+TW+NY+ C F + K + LY + VG+S+S +L +++ I +FR L C R
Sbjct: 126 RTWSNYTMCNAFTPEKL---KNAYV--LYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQR 180
Query: 177 NYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGC 236
+H ++F++++L + I + H+ +++ DP + C
Sbjct: 181 VTLHKNMFLTYILNSMIIII-------HLVEVVPNGELVRRDP--------------VSC 219
Query: 237 KIAVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAV 296
KI Y +A NY+W+L EG+YLH LI VA F++ + L + L+GWGFP A+
Sbjct: 220 KILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAI 279
Query: 297 ARATLADARCWELSAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETN-AVGHDTR 355
RA + CW + +I P++AA+ +NF LN VRVL TK+ ET+ A H
Sbjct: 280 TRAVYFNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESH--- 336
Query: 356 KQYRKLAKSTLVLVLVFGVHYIVFVCLP-HSFTGLGWEIRMHCELFFNSFQGFFVSIIYC 414
Y K K+T++LV + G+ ++VF P + G ++ MH + FQGFFV+ IYC
Sbjct: 337 -MYLKAVKATMILVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLI---HFQGFFVATIYC 392
Query: 415 YCNGEVQAEVKKMWSRWNLSVD--WKRTPPCGSRRCGS 450
+CN EVQ VK+ W+++ + + W R P S R +
Sbjct: 393 FCNNEVQTTVKRQWAQFKIQWNQRWGRRPSNRSARAAA 430
>gi|32307159 corticotropin releasing hormone receptor 2 [Homo
sapiens]
Length = 411
Score = 199 bits (506), Expect = 5e-51
Identities = 120/368 (32%), Positives = 177/368 (48%), Gaps = 48/368 (13%)
Query: 72 CWPRGTVGKISAVPCPPYI--YDFNHKGVAFRHCNPNGTWDFMHSLNKTWANYSDCLRFL 129
CWPR G + PCP Y +N A+R C NGTW + NYS C L
Sbjct: 50 CWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGTW-------ASKINYSQCEPIL 102
Query: 130 QPDISIGKQEFFERLY----VMYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHMHLFV 185
KQ ++ Y V+ +G+ +S +L A L+ R + C RN IH +L
Sbjct: 103 DD-----KQRKYDLHYRIALVVNYLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLIT 157
Query: 186 SFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKIAVVMFIY 245
+F+LR F+ V H V +S + C+ +F Y
Sbjct: 158 TFILRNVMWFLLQLVDH------------------------EVHESNEVWCRCITTIFNY 193
Query: 246 FLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAVARATLADAR 305
F+ TN++W+ VEG YLH I + + ++ F+ IGW P + AWA+ + + +
Sbjct: 194 FVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQ 253
Query: 306 CW-ELSAGD-IKWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTRKQYRKLAK 363
CW GD + +IYQ PI+ + +NF+ N VR+L TK+ A QYRK K
Sbjct: 254 CWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKL---RASTTSETIQYRKAVK 310
Query: 364 STLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFFVSIIYCYCNGEVQAE 423
+TLVL+ + G+ Y++F P L + ++ F SFQGFFVS+ YC+ NGEV++
Sbjct: 311 ATLVLLPLLGITYMLFFVNPGE-DDLSQIMFIYFNSFLQSFQGFFVSVFYCFFNGEVRSA 369
Query: 424 VKKMWSRW 431
V+K W RW
Sbjct: 370 VRKRWHRW 377
>gi|5031621 calcitonin receptor-like [Homo sapiens]
Length = 461
Score = 198 bits (503), Expect = 1e-50
Identities = 117/418 (27%), Positives = 201/418 (48%), Gaps = 35/418 (8%)
Query: 20 LLARAQLDSDGTITIEEQIVL--VLKAKVQCELNITAQ-LQEGEG-NCFPEWDGLICWPR 75
+L A+L+ +I+ + ++ A+ +C I +Q+ EG C WDG +CW
Sbjct: 18 ILVTAELEESPEDSIQLGVTRNKIMTAQYECYQKIMQDPIQQAEGVYCNRTWDGWLCWND 77
Query: 76 GTVGKISAVPCPPYIYDFNHKGVAFRHCNPNGTWDFMHSLNKTWANYSDCLRFLQPDISI 135
G S CP Y DF+ + C+ +G W + N+TW NY+ C +
Sbjct: 78 VAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRTWTNYTQCNVNTHEKVKT 137
Query: 136 GKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHMHLFVSFMLRATSIF 195
F+ + +G+ +S SL +++ I YF+ L C R +H +LF SF+ +
Sbjct: 138 ALNLFY-----LTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSVVTI 192
Query: 196 VKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKIAVVMFIYFLATNYYWIL 255
+ H+ ++ +P + CK++ + +Y + NY+W+L
Sbjct: 193 I-------HLTAVANNQALVATNP--------------VSCKVSQFIHLYLMGCNYFWML 231
Query: 256 VEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAVARATLADARCWELSAGDIK 315
EG+YLH LI VA F++ ++L + +GWGFP A+AR+ + CW S +
Sbjct: 232 CEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLL 291
Query: 316 WIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTRKQYRKLAKSTLVLVLVFGVH 375
+I PI AA+ +N LN VRVL TK+ T+ + Y K ++TL+LV + G+
Sbjct: 292 YIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNL---YMKAVRATLILVPLLGIE 348
Query: 376 YIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFFVSIIYCYCNGEVQAEVKKMWSRWNL 433
+++ P + E+ + FQG VS I+C+ NGEVQA +++ W+++ +
Sbjct: 349 FVLIPWRPEG--KIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKI 404
>gi|19923245 corticotropin releasing hormone receptor 1 isoform 2
[Homo sapiens]
Length = 415
Score = 196 bits (499), Expect = 4e-50
Identities = 113/364 (31%), Positives = 175/364 (48%), Gaps = 40/364 (10%)
Query: 72 CWPRGTVGKISAVPCPPYIYD--FNHKGVAFRHCNPNGTWDFMHSLNKTWANYSDCLRFL 129
CWPR G++ PCP + Y +N +R C NG+W NYS+C L
Sbjct: 54 CWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSW-------AARVNYSECQEIL 106
Query: 130 QPDISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHMHLFVSFML 189
+ K + + + Y +G+ IS +L VA ++ R + C RN IH +L +F+L
Sbjct: 107 NEEKK-SKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFIL 164
Query: 190 RATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKIAVVMFIYFLAT 249
R + FV + + V +S C++ + YF T
Sbjct: 165 RNATWFVVQLTM-----------------------SPEVHQSNVGWCRLVTAAYNYFHVT 201
Query: 250 NYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAVARATLADARCWEL 309
N++W+ EG YLH I + + +D W FI IGWG P + AWA+ + + +CW
Sbjct: 202 NFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFG 261
Query: 310 SAGDI--KWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTRKQYRKLAKSTLV 367
+ +IYQ P++ + +NFI N VR+L TK+ A QYRK K+TLV
Sbjct: 262 KRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKL---RASTTSETIQYRKAVKATLV 318
Query: 368 LVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFFVSIIYCYCNGEVQAEVKKM 427
L+ + G+ Y++F P + + ++ F SFQGFFVS+ YC+ N EV++ ++K
Sbjct: 319 LLPLLGITYMLFFVNPGE-DEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKR 377
Query: 428 WSRW 431
W RW
Sbjct: 378 WHRW 381
>gi|223717971 corticotropin releasing hormone receptor 1 isoform 1
[Homo sapiens]
Length = 444
Score = 181 bits (459), Expect = 2e-45
Identities = 113/393 (28%), Positives = 175/393 (44%), Gaps = 69/393 (17%)
Query: 72 CWPRGTVGKISAVPCPPYIYD--FNHKGVAFRHCNPNGTWDFMHSLNKTWANYSDCLRFL 129
CWPR G++ PCP + Y +N +R C NG+W NYS+C L
Sbjct: 54 CWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSW-------AARVNYSECQEIL 106
Query: 130 QPDISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFR------------------- 170
+ K + + + Y +G+ IS +L VA ++ R
Sbjct: 107 NEEKK-SKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVGAP 164
Query: 171 ----------RLHCTRNYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQ 220
+ C RN IH +L +F+LR + FV +
Sbjct: 165 WSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQLTM------------------- 205
Query: 221 NSIEATSVDKSQYIGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFI 280
+ V +S C++ + YF TN++W+ EG YLH I + + +D W FI
Sbjct: 206 ----SPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFI 261
Query: 281 LIGWGFPAAFVAAWAVARATLADARCWELSAGDI--KWIYQAPILAAIGLNFILFLNTVR 338
IGWG P + AWA+ + + +CW + +IYQ P++ + +NFI N VR
Sbjct: 262 CIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVR 321
Query: 339 VLATKIWETNAVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCE 398
+L TK+ A QYRK K+TLVL+ + G+ Y++F P + + ++
Sbjct: 322 ILMTKL---RASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGE-DEVSRVVFIYFN 377
Query: 399 LFFNSFQGFFVSIIYCYCNGEVQAEVKKMWSRW 431
F SFQGFFVS+ YC+ N EV++ ++K W RW
Sbjct: 378 SFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRW 410
>gi|223717978 corticotropin releasing hormone receptor 1 isoform 3
[Homo sapiens]
Length = 375
Score = 175 bits (443), Expect = 1e-43
Identities = 103/334 (30%), Positives = 161/334 (48%), Gaps = 38/334 (11%)
Query: 100 FRHCNPNGTWDFMHSLNKTWANYSDCLRFLQPDISIGKQEFFERLYVMYTVGYSISFGSL 159
+R C NG+W NYS+C L + K + + + Y +G+ IS +L
Sbjct: 44 YRECLANGSW-------AARVNYSECQEILNEEKK-SKVHYHVAVIINY-LGHCISLVAL 94
Query: 160 AVAILIIGYFRRLHCTRNYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDP 219
VA ++ R + C RN IH +L +F+LR + FV +
Sbjct: 95 LVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTM------------------ 136
Query: 220 QNSIEATSVDKSQYIGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGF 279
+ V +S C++ + YF TN++W+ EG YLH I + + +D W F
Sbjct: 137 -----SPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMF 191
Query: 280 ILIGWGFPAAFVAAWAVARATLADARCWELSAGDI--KWIYQAPILAAIGLNFILFLNTV 337
I IGWG P + AWA+ + + +CW + +IYQ P++ + +NFI N V
Sbjct: 192 ICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIV 251
Query: 338 RVLATKIWETNAVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHC 397
R+L TK+ A QYRK K+TLVL+ + G+ Y++F P + + ++
Sbjct: 252 RILMTKL---RASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGE-DEVSRVVFIYF 307
Query: 398 ELFFNSFQGFFVSIIYCYCNGEVQAEVKKMWSRW 431
F SFQGFFVS+ YC+ N EV++ ++K W RW
Sbjct: 308 NSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRW 341
>gi|223717985 corticotropin releasing hormone receptor 1 isoform 4
[Homo sapiens]
Length = 401
Score = 169 bits (428), Expect = 6e-42
Identities = 106/364 (29%), Positives = 166/364 (45%), Gaps = 54/364 (14%)
Query: 72 CWPRGTVGKISAVPCPPYIYD--FNHKGVAFRHCNPNGTWDFMHSLNKTWANYSDCLRFL 129
CWPR G++ PCP + Y +N +R C NG+W NYS+C L
Sbjct: 54 CWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSW-------AARVNYSECQEIL 106
Query: 130 QPDISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHMHLFVSFML 189
+ K + + + Y +G+ IS +L VA ++ R + C RN IH +L +F+L
Sbjct: 107 NEEKK-SKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFIL 164
Query: 190 RATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKIAVVMFIYFLAT 249
R + FV + + V +S C++ + YF T
Sbjct: 165 RNATWFVVQLTM-----------------------SPEVHQSNVGWCRLVTAAYNYFHVT 201
Query: 250 NYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAVARATLADARCWEL 309
N++W+ EG YLH I + + +D W FI IGWG P + AWA+ + + +CW
Sbjct: 202 NFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFG 261
Query: 310 SAGDI--KWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTRKQYRKLAKSTLV 367
+ +IYQ P++ + +NFI N VR+L TK+ A QYRK K+TLV
Sbjct: 262 KRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKL---RASTTSETIQYRKAVKATLV 318
Query: 368 LVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFFVSIIYCYCNGEVQAEVKKM 427
L+ + G+ Y++F P E+ ++FNSF F +V++ ++K
Sbjct: 319 LLPLLGITYMLFFVNPGED-----EVSRVVFIYFNSFLESF----------QVRSAIRKR 363
Query: 428 WSRW 431
W RW
Sbjct: 364 WHRW 367
>gi|58530853 growth hormone releasing hormone receptor isoform b
precursor [Homo sapiens]
Length = 337
Score = 165 bits (417), Expect = 1e-40
Identities = 95/301 (31%), Positives = 145/301 (48%), Gaps = 36/301 (11%)
Query: 63 CFPEWDGLICWPRGTVGKISAVPCPPYIYDFNHK-GVAFRHCNPNGTWDFMHSLNKTWAN 121
C WDGL+CWP G+ +PCP + F+ + G R C G W+
Sbjct: 55 CPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITG-----------WSE 103
Query: 122 YSDCLRFLQP---DISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNY 178
P ++ ++ +F + ++YTVG+SIS +L VAI I+ RRLHC RNY
Sbjct: 104 PFPPYPVACPVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNY 163
Query: 179 IHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKI 238
+H LF +F+L+A ++F+KD +L DD + +T + CK+
Sbjct: 164 VHTQLFTTFILKAGAVFLKD------------AALFHSDDTDHCSFST-------VLCKV 204
Query: 239 AVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAVAR 298
+V + TN+ W+L E +YL+ L+ S + W +L GWG P F W +
Sbjct: 205 SVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCK 264
Query: 299 ATLADARCWEL-SAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTRKQ 357
D CW+L WI + PI+ ++G+NF LFLN +R+L K+ H T+ Q
Sbjct: 265 LAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLH-TQSQ 323
Query: 358 Y 358
Y
Sbjct: 324 Y 324
>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
Length = 874
Score = 83.2 bits (204), Expect = 6e-16
Identities = 56/210 (26%), Positives = 99/210 (47%), Gaps = 13/210 (6%)
Query: 236 CKIAVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDT---KYLWGFILIGWGFPAAF-V 291
C++ V+ YF + + W+LVEGL+L++++ F S+ +Y +G +GWGFP +
Sbjct: 632 CQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYG---MGWGFPLLICI 688
Query: 292 AAWAVARATLADA-RCWELSAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAV 350
+ + A + + CW A W + AP L I +N + + RV+ ++I N
Sbjct: 689 ISLSFAMDSYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGILIAVTRVI-SQISADNYK 747
Query: 351 GHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFFVS 410
H ++ AK+ VL+ + G ++ V + + + NS QG F+
Sbjct: 748 IHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGCA----VVFQYMFATLNSLQGLFIF 803
Query: 411 IIYCYCNGEVQAEVKKMWSRWNLSVDWKRT 440
+ +C N EV+A K W+L+ RT
Sbjct: 804 LFHCLLNSEVRAAFKHKTKVWSLTSSSART 833
>gi|133930786 egf-like module-containing mucin-like receptor 3 [Homo
sapiens]
Length = 652
Score = 73.2 bits (178), Expect = 6e-13
Identities = 73/305 (23%), Positives = 122/305 (40%), Gaps = 42/305 (13%)
Query: 133 ISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHMHLFVSFMLRAT 192
+++ QE L V+ VG S+S L +A L + + T +H+ L + L A
Sbjct: 345 MALTSQEEDPVLTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLFL-AH 403
Query: 193 SIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKIAVVMFIYFLATNYY 252
+F+ +G+ E ++ C I Y +
Sbjct: 404 LLFL--------VGIDRTEPKVL--------------------CSIIAGALHYLYLAAFT 435
Query: 253 WILVEGLYL----HNLIFVAFFSDTKYL-WGFILIGWGFPAAFVAAWAVARATLADA--R 305
W+L+EG++L NL V + S + + W +G+G PA VA A + L R
Sbjct: 436 WMLLEGVHLFLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTADR 495
Query: 306 CWELSAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTRKQYRKLAKST 365
CW W + P+ A N +LF+ +L K+ N+ T + R LA
Sbjct: 496 CWLHLDQGFMWSFLGPVCAIFSANLVLFILVFWILKRKLSSLNSEV-STIQNTRMLAFKA 554
Query: 366 LVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFFVSIIYCYCNGEVQAEVK 425
+ + G + CL G ++ + NS QGFF+ ++YC + +VQ + +
Sbjct: 555 TAQLFILGCTW----CLGLLQVGPAAQVMAYLFTIINSLQGFFIFLVYCLLSQQVQKQYQ 610
Query: 426 KMWSR 430
K W R
Sbjct: 611 K-WFR 614
>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
Length = 1474
Score = 72.8 bits (177), Expect = 8e-13
Identities = 86/340 (25%), Positives = 143/340 (42%), Gaps = 68/340 (20%)
Query: 144 LYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHMHLFVSFMLRATSIFVKDRVVHA 203
L V+ VG IS LA+ I + R L RN IH +L ++ L A +F+
Sbjct: 860 LSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFL-AELLFL------- 911
Query: 204 HIGVKELESLIMQDDPQNSIEATSVDKSQY-IGCKIAVVMFIYFLATNYYWILVEGLYLH 262
+DK+QY I C I + YF + W+ +EG++L+
Sbjct: 912 ----------------------VGIDKTQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLY 949
Query: 263 NL---IFVAFFSDTKYLWGFILIGWGFPAAFV--AAWAVARATLADARCWELSAGDIKWI 317
L +F + +S TKY + L G+ FPA V AA R+ + CW W
Sbjct: 950 LLLVEVFESEYSRTKY---YYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWS 1006
Query: 318 YQAPILAAIGLNFILFLNTVR--VLATKIWETNAVGHDTRKQYRKLAKSTLVLV---LVF 372
+ P+ I +N + + T+ + ++ + + ++ D K + A + L L+ F
Sbjct: 1007 FIGPVSFVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAF 1066
Query: 373 GVHYI--VFVCLPHSFTGLGWEIRMHCELFFNSFQGFFVSIIYCYCNGEVQAEVKKMWSR 430
G+ +I V + + FT FN+FQG F+ + +C +V E K
Sbjct: 1067 GLLFINKESVVMAYLFT------------TFNAFQGVFIFVFHCALQKKVHKEYSKCLRH 1114
Query: 431 WNLSVDWKRTPPCGSRRCGSVLTTVTHS-----TSSQSQV 465
+ R+PP G+ GS+ T+ S T +QS++
Sbjct: 1115 SYCCI---RSPPGGTH--GSLKTSAMRSNTRYYTGTQSRI 1149
>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
Length = 1469
Score = 72.8 bits (177), Expect = 8e-13
Identities = 86/340 (25%), Positives = 143/340 (42%), Gaps = 68/340 (20%)
Query: 144 LYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHMHLFVSFMLRATSIFVKDRVVHA 203
L V+ VG IS LA+ I + R L RN IH +L ++ L A +F+
Sbjct: 855 LSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFL-AELLFL------- 906
Query: 204 HIGVKELESLIMQDDPQNSIEATSVDKSQY-IGCKIAVVMFIYFLATNYYWILVEGLYLH 262
+DK+QY I C I + YF + W+ +EG++L+
Sbjct: 907 ----------------------VGIDKTQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLY 944
Query: 263 NL---IFVAFFSDTKYLWGFILIGWGFPAAFV--AAWAVARATLADARCWELSAGDIKWI 317
L +F + +S TKY + L G+ FPA V AA R+ + CW W
Sbjct: 945 LLLVEVFESEYSRTKY---YYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWS 1001
Query: 318 YQAPILAAIGLNFILFLNTVR--VLATKIWETNAVGHDTRKQYRKLAKSTLVLV---LVF 372
+ P+ I +N + + T+ + ++ + + ++ D K + A + L L+ F
Sbjct: 1002 FIGPVSFVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAF 1061
Query: 373 GVHYI--VFVCLPHSFTGLGWEIRMHCELFFNSFQGFFVSIIYCYCNGEVQAEVKKMWSR 430
G+ +I V + + FT FN+FQG F+ + +C +V E K
Sbjct: 1062 GLLFINKESVVMAYLFT------------TFNAFQGVFIFVFHCALQKKVHKEYSKCLRH 1109
Query: 431 WNLSVDWKRTPPCGSRRCGSVLTTVTHS-----TSSQSQV 465
+ R+PP G+ GS+ T+ S T +QS++
Sbjct: 1110 SYCCI---RSPPGGTH--GSLKTSAMRSNTRYYTGTQSRI 1144
>gi|23397681 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform a [Homo sapiens]
Length = 823
Score = 72.0 bits (175), Expect = 1e-12
Identities = 54/202 (26%), Positives = 88/202 (43%), Gaps = 13/202 (6%)
Query: 236 CKIAVVMFIYFLATNYYWILVEGLYL----HNLIFVAFFSDTKYLWGFIL-IGWGFPAAF 290
C I Y W+L+E LYL NL V + S +++ + +G+G PA
Sbjct: 599 CSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVT 658
Query: 291 VAAWAVARATL--ADARCWELSAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETN 348
VA A +R L +RCW W + P+ A +N +LFL T+ +L ++ N
Sbjct: 659 VAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLN 718
Query: 349 AVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFF 408
+ T + R LA + + G + CL G + + NS QG F
Sbjct: 719 S-EVSTLRNTRMLAFKATAQLFILGCTW----CLGILQVGPAARVMAYLFTIINSLQGVF 773
Query: 409 VSIIYCYCNGEVQAEVKKMWSR 430
+ ++YC + +V+ + K WS+
Sbjct: 774 IFLVYCLLSQQVREQYGK-WSK 794
>gi|23397693 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform g [Homo sapiens]
Length = 719
Score = 72.0 bits (175), Expect = 1e-12
Identities = 54/202 (26%), Positives = 88/202 (43%), Gaps = 13/202 (6%)
Query: 236 CKIAVVMFIYFLATNYYWILVEGLYL----HNLIFVAFFSDTKYLWGFIL-IGWGFPAAF 290
C I Y W+L+E LYL NL V + S +++ + +G+G PA
Sbjct: 495 CSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVT 554
Query: 291 VAAWAVARATL--ADARCWELSAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETN 348
VA A +R L +RCW W + P+ A +N +LFL T+ +L ++ N
Sbjct: 555 VAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLN 614
Query: 349 AVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFF 408
+ T + R LA + + G + CL G + + NS QG F
Sbjct: 615 S-EVSTLRNTRMLAFKATAQLFILGCTW----CLGILQVGPAARVMAYLFTIINSLQGVF 669
Query: 409 VSIIYCYCNGEVQAEVKKMWSR 430
+ ++YC + +V+ + K WS+
Sbjct: 670 IFLVYCLLSQQVREQYGK-WSK 690
>gi|23397691 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform f [Homo sapiens]
Length = 763
Score = 72.0 bits (175), Expect = 1e-12
Identities = 54/202 (26%), Positives = 88/202 (43%), Gaps = 13/202 (6%)
Query: 236 CKIAVVMFIYFLATNYYWILVEGLYL----HNLIFVAFFSDTKYLWGFIL-IGWGFPAAF 290
C I Y W+L+E LYL NL V + S +++ + +G+G PA
Sbjct: 539 CSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVT 598
Query: 291 VAAWAVARATL--ADARCWELSAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETN 348
VA A +R L +RCW W + P+ A +N +LFL T+ +L ++ N
Sbjct: 599 VAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLN 658
Query: 349 AVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFF 408
+ T + R LA + + G + CL G + + NS QG F
Sbjct: 659 S-EVSTLRNTRMLAFKATAQLFILGCTW----CLGILQVGPAARVMAYLFTIINSLQGVF 713
Query: 409 VSIIYCYCNGEVQAEVKKMWSR 430
+ ++YC + +V+ + K WS+
Sbjct: 714 IFLVYCLLSQQVREQYGK-WSK 734
>gi|23397689 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform e [Homo sapiens]
Length = 812
Score = 72.0 bits (175), Expect = 1e-12
Identities = 54/202 (26%), Positives = 88/202 (43%), Gaps = 13/202 (6%)
Query: 236 CKIAVVMFIYFLATNYYWILVEGLYL----HNLIFVAFFSDTKYLWGFIL-IGWGFPAAF 290
C I Y W+L+E LYL NL V + S +++ + +G+G PA
Sbjct: 588 CSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVT 647
Query: 291 VAAWAVARATL--ADARCWELSAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETN 348
VA A +R L +RCW W + P+ A +N +LFL T+ +L ++ N
Sbjct: 648 VAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLN 707
Query: 349 AVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFF 408
+ T + R LA + + G + CL G + + NS QG F
Sbjct: 708 S-EVSTLRNTRMLAFKATAQLFILGCTW----CLGILQVGPAARVMAYLFTIINSLQGVF 762
Query: 409 VSIIYCYCNGEVQAEVKKMWSR 430
+ ++YC + +V+ + K WS+
Sbjct: 763 IFLVYCLLSQQVREQYGK-WSK 783
>gi|23397687 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform d [Homo sapiens]
Length = 681
Score = 72.0 bits (175), Expect = 1e-12
Identities = 54/202 (26%), Positives = 88/202 (43%), Gaps = 13/202 (6%)
Query: 236 CKIAVVMFIYFLATNYYWILVEGLYL----HNLIFVAFFSDTKYLWGFIL-IGWGFPAAF 290
C I Y W+L+E LYL NL V + S +++ + +G+G PA
Sbjct: 457 CSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVT 516
Query: 291 VAAWAVARATL--ADARCWELSAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETN 348
VA A +R L +RCW W + P+ A +N +LFL T+ +L ++ N
Sbjct: 517 VAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLN 576
Query: 349 AVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFF 408
+ T + R LA + + G + CL G + + NS QG F
Sbjct: 577 S-EVSTLRNTRMLAFKATAQLFILGCTW----CLGILQVGPAARVMAYLFTIINSLQGVF 631
Query: 409 VSIIYCYCNGEVQAEVKKMWSR 430
+ ++YC + +V+ + K WS+
Sbjct: 632 IFLVYCLLSQQVREQYGK-WSK 652
>gi|23397685 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform c [Homo sapiens]
Length = 730
Score = 72.0 bits (175), Expect = 1e-12
Identities = 54/202 (26%), Positives = 88/202 (43%), Gaps = 13/202 (6%)
Query: 236 CKIAVVMFIYFLATNYYWILVEGLYL----HNLIFVAFFSDTKYLWGFIL-IGWGFPAAF 290
C I Y W+L+E LYL NL V + S +++ + +G+G PA
Sbjct: 506 CSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVT 565
Query: 291 VAAWAVARATL--ADARCWELSAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETN 348
VA A +R L +RCW W + P+ A +N +LFL T+ +L ++ N
Sbjct: 566 VAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLN 625
Query: 349 AVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFF 408
+ T + R LA + + G + CL G + + NS QG F
Sbjct: 626 S-EVSTLRNTRMLAFKATAQLFILGCTW----CLGILQVGPAARVMAYLFTIINSLQGVF 680
Query: 409 VSIIYCYCNGEVQAEVKKMWSR 430
+ ++YC + +V+ + K WS+
Sbjct: 681 IFLVYCLLSQQVREQYGK-WSK 701
>gi|23397683 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform b [Homo sapiens]
Length = 774
Score = 72.0 bits (175), Expect = 1e-12
Identities = 54/202 (26%), Positives = 88/202 (43%), Gaps = 13/202 (6%)
Query: 236 CKIAVVMFIYFLATNYYWILVEGLYL----HNLIFVAFFSDTKYLWGFIL-IGWGFPAAF 290
C I Y W+L+E LYL NL V + S +++ + +G+G PA
Sbjct: 550 CSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVT 609
Query: 291 VAAWAVARATL--ADARCWELSAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETN 348
VA A +R L +RCW W + P+ A +N +LFL T+ +L ++ N
Sbjct: 610 VAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLN 669
Query: 349 AVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFF 408
+ T + R LA + + G + CL G + + NS QG F
Sbjct: 670 S-EVSTLRNTRMLAFKATAQLFILGCTW----CLGILQVGPAARVMAYLFTIINSLQGVF 724
Query: 409 VSIIYCYCNGEVQAEVKKMWSR 430
+ ++YC + +V+ + K WS+
Sbjct: 725 IFLVYCLLSQQVREQYGK-WSK 745
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.138 0.452
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,697,781
Number of Sequences: 37866
Number of extensions: 883345
Number of successful extensions: 2888
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 43
Number of HSP's that attempted gapping in prelim test: 2644
Number of HSP's gapped (non-prelim): 109
length of query: 550
length of database: 18,247,518
effective HSP length: 107
effective length of query: 443
effective length of database: 14,195,856
effective search space: 6288764208
effective search space used: 6288764208
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.