Search of human proteins with 4826940

Search of human proteins with 4826940

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4826940 prolylcarboxypeptidase isoform 1 preproprotein [Homo
sapiens]
         (496 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4826940 prolylcarboxypeptidase isoform 1 preproprotein [Homo ...  1036   0.0  
gi|117306169 prolylcarboxypeptidase isoform 2 preproprotein [Hom...  1023   0.0  
gi|62420888 dipeptidyl peptidase 7 preproprotein [Homo sapiens]       367   e-101
gi|5031993 protease, serine, 16 [Homo sapiens]                        133   3e-31
gi|15100151 HLA-B associated transcript 5 [Homo sapiens]               33   0.60 
gi|28629871 hypothetical protein LOC140701 [Homo sapiens]              32   1.3  
gi|7662058 tectonin beta-propeller repeat containing 2 [Homo sap...    30   6.6  
gi|222080058 Smith-Magenis syndrome chromosome region, candidate...    30   6.6  
gi|22538488 Smith-Magenis syndrome chromosome region, candidate ...    30   6.6  
gi|10190704 2,4-dienoyl CoA reductase 2 [Homo sapiens]                 29   8.6  

>gi|4826940 prolylcarboxypeptidase isoform 1 preproprotein [Homo
           sapiens]
          Length = 496

 Score = 1036 bits (2678), Expect = 0.0
 Identities = 496/496 (100%), Positives = 496/496 (100%)

Query: 1   MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKVDHF 60
           MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKVDHF
Sbjct: 1   MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKVDHF 60

Query: 61  GFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFA 120
           GFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFA
Sbjct: 61  GFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFA 120

Query: 121 EHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSY 180
           EHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSY
Sbjct: 121 EHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSY 180

Query: 181 GGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIHRS 240
           GGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIHRS
Sbjct: 181 GGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIHRS 240

Query: 241 WDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQP 300
           WDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQP
Sbjct: 241 WDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQP 300

Query: 301 LPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWS 360
           LPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWS
Sbjct: 301 LPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWS 360

Query: 361 YQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHT 420
           YQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHT
Sbjct: 361 YQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHT 420

Query: 421 NIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRH 480
           NIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRH
Sbjct: 421 NIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRH 480

Query: 481 MKNWIRDFYDSAGKQH 496
           MKNWIRDFYDSAGKQH
Sbjct: 481 MKNWIRDFYDSAGKQH 496


>gi|117306169 prolylcarboxypeptidase isoform 2 preproprotein [Homo
           sapiens]
          Length = 517

 Score = 1023 bits (2646), Expect = 0.0
 Identities = 496/517 (95%), Positives = 496/517 (95%), Gaps = 21/517 (4%)

Query: 1   MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQK---- 56
           MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQK    
Sbjct: 1   MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKALAA 60

Query: 57  -----------------VDHFGFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWF 99
                            VDHFGFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWF
Sbjct: 61  GQLHICIIQLNHYKTPLVDHFGFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWF 120

Query: 100 CNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIK 159
           CNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIK
Sbjct: 121 CNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIK 180

Query: 160 HLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFM 219
           HLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFM
Sbjct: 181 HLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFM 240

Query: 220 KIVTTDFRKSGPHCSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWI 279
           KIVTTDFRKSGPHCSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWI
Sbjct: 241 KIVTTDFRKSGPHCSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWI 300

Query: 280 SETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSG 339
           SETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSG
Sbjct: 301 SETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSG 360

Query: 340 QVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWG 399
           QVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWG
Sbjct: 361 QVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWG 420

Query: 400 VRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDL 459
           VRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDL
Sbjct: 421 VRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDL 480

Query: 460 RTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGKQH 496
           RTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGKQH
Sbjct: 481 RTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGKQH 517


>gi|62420888 dipeptidyl peptidase 7 preproprotein [Homo sapiens]
          Length = 492

 Score =  367 bits (941), Expect = e-101
 Identities = 205/486 (42%), Positives = 284/486 (58%), Gaps = 29/486 (5%)

Query: 15  APWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKVDHFGFNTV--KTFNQRY 72
           APWA + L     ALG   L       P     +   +FQQ++DHF F     KTF QR+
Sbjct: 4   APWAPVLLL----ALGLRGLQAGARRAPD--PGFQERFFQQRLDHFNFERFGNKTFPQRF 57

Query: 73  LVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFG 132
           LV+D++W +  G I FYTGNEGD+  F NN+ F+ ++A E  A+LVFAEHRYYG+SLPFG
Sbjct: 58  LVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFG 117

Query: 133 DNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKY 192
             S +   H   LT EQALADFAEL++ L+R + GA++ P IA GGSYGGML+A+ RMKY
Sbjct: 118 AQSTQRG-HTELLTVEQALADFAELLRALRRDL-GAQDAPAIAFGGSYGGMLSAYLRMKY 175

Query: 193 PHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIHRSWDAINRLSNTGS 252
           PH+V GALAASAP+     L     F + VT DF    P C++ +  ++  I  L   G+
Sbjct: 176 PHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGA 235

Query: 253 --GLQWLTGALHLCSPLTSQ-DIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVV 309
              ++W  G    C PL+ + D+  L  +    +  LAM+DYPY ++FL PLPA P+KV 
Sbjct: 236 YDTVRWEFGT---CQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVG 292

Query: 310 CQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLG---------WS 360
           C  L    +S++  +  +     + YN SG   C +I     S     G         W 
Sbjct: 293 CDRL----LSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWD 348

Query: 361 YQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHT 420
           YQACTE+ + F +N V DMF    +  +     C   WGV PRP W+ T + G ++ + +
Sbjct: 349 YQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAAS 408

Query: 421 NIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRH 480
           NI+FSNG LDPW+GGG+ ++++ +++AVTI  GAHHLDLR  +  DP SV+ AR LE   
Sbjct: 409 NIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATI 468

Query: 481 MKNWIR 486
           +  W++
Sbjct: 469 IGEWVK 474


>gi|5031993 protease, serine, 16 [Homo sapiens]
          Length = 514

 Score =  133 bits (335), Expect = 3e-31
 Identities = 136/508 (26%), Positives = 214/508 (42%), Gaps = 45/508 (8%)

Query: 8   LLLLSFLAPWATIALRPALRALGSLHLPTNPTSL--------PAVAKNYSVLYFQQKVDH 59
           LLL+S    W  +A    LR LG        +S         P  A    V + +Q +D 
Sbjct: 12  LLLVSL---WGLLAPASLLRRLGEHIQQFQESSAQGLGLSLGPGAAALPKVGWLEQLLDP 68

Query: 60  FGFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVF 119
           F  +  ++F QRY V D++W    G I  + G EG +       G    +A    A+++ 
Sbjct: 69  FNVSDRRSFLQRYWVNDQHWVGQDGPIFLHLGGEGSLGPGSVMRGHPAALAPAWGALVIS 128

Query: 120 AEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGS 179
            EHR+YG S+P G     +   L FL+S  ALAD       L R    + + P I  GGS
Sbjct: 129 LEHRFYGLSIPAGG---LEMAQLRFLSSRLALADVVSARLALSRLFNISSSSPWICFGGS 185

Query: 180 YGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCG-VFMKIVTTDFRKSGPHCSESIH 238
           Y G LAAW R+K+PH++  ++A+SAP+    D      V  + + +        C  ++ 
Sbjct: 186 YAGSLAAWARLKFPHLIFASVASSAPVRAVLDFSEYNDVVSRSLMSTAIGGSLECRAAVS 245

Query: 239 RSWDAINRLSNTGSGLQ-WLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNF 297
            ++  + R   +G   Q  L   L  C PL   + Q       +  V   +V Y   +  
Sbjct: 246 VAFAEVERRLRSGGAAQAALRTELSACGPLGRAENQAELLGALQALVG-GVVQYDGQTG- 303

Query: 298 LQPLPAWPIKVVCQYL--KNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETAT---- 351
             PL    ++ +C  L     N S S     + +A+ +  +  GQ KCL+ S   T    
Sbjct: 304 -APL---SVRQLCGLLLGGGGNRSHSTPYCGLRRAVQIVLHSLGQ-KCLSFSRAETVAQL 358

Query: 352 -------SSLGTLGWSYQACTEV-VMPFCTNGVDDMFEPHSWNLKELSDDCFQQWG---- 399
                  S +G   W YQ CTE      C N      +  +  L    D C Q +G    
Sbjct: 359 RSTEPQLSGVGDRQWLYQTCTEFGFYVTCENPRCPFSQLPA--LPSQLDLCEQVFGLSAL 416

Query: 400 -VRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLD 458
            V    +   + YGG+   ++  ++F NG+ DPW    VT+ +  +   + I  G+H LD
Sbjct: 417 SVAQAVAQTNSYYGGQTPGAN-KVLFVNGDTDPWHVLSVTQALGSSESTLLIRTGSHCLD 475

Query: 459 LRTKNALDPMSVLLARSLEVRHMKNWIR 486
           +  +   D  S+ L R    + ++ W++
Sbjct: 476 MAPERPSDSPSLRLGRQNIFQQLQTWLK 503


>gi|15100151 HLA-B associated transcript 5 [Homo sapiens]
          Length = 558

 Score = 33.1 bits (74), Expect = 0.60
 Identities = 21/61 (34%), Positives = 30/61 (49%), Gaps = 7/61 (11%)

Query: 167 GAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDF 226
           G + Q +I    S GG  A W  M YP +    L AS     F+DLVP  + +K++   +
Sbjct: 343 GFQPQDIIIYAWSIGGFTATWAAMSYPDVSAMILDAS-----FDDLVP--LALKVMPDSW 395

Query: 227 R 227
           R
Sbjct: 396 R 396


>gi|28629871 hypothetical protein LOC140701 [Homo sapiens]
          Length = 469

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 5/42 (11%)

Query: 173 VIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVP 214
           ++  G S GG  A W  M YP +  GAL   A    F+DLVP
Sbjct: 241 LVVYGWSVGGFTATWATMTYPEL--GALVLDA---TFDDLVP 277


>gi|7662058 tectonin beta-propeller repeat containing 2 [Homo sapiens]
          Length = 1411

 Score = 29.6 bits (65), Expect = 6.6
 Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 5/42 (11%)

Query: 70   QRYLVADK-----YWKKNGGSILFYTGNEGDIIWFCNNTGFM 106
            +RY V DK     YWKK  GS+  +T    D +W     G++
Sbjct: 1335 RRYGVTDKNPAGDYWKKIPGSVSCFTVTASDELWAVGPPGYL 1376


>gi|222080058 Smith-Magenis syndrome chromosome region, candidate 7
           isoform 2 [Homo sapiens]
          Length = 465

 Score = 29.6 bits (65), Expect = 6.6
 Identities = 14/44 (31%), Positives = 21/44 (47%)

Query: 164 TIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIW 207
           TIP A+      + G     L A+FR K+P +  GA     P++
Sbjct: 151 TIPAAQVALAKQLAGDIALELQAYFRSKFPELPFGAFVPGGPLY 194


>gi|22538488 Smith-Magenis syndrome chromosome region, candidate 7
           isoform 1 [Homo sapiens]
          Length = 454

 Score = 29.6 bits (65), Expect = 6.6
 Identities = 14/44 (31%), Positives = 21/44 (47%)

Query: 164 TIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIW 207
           TIP A+      + G     L A+FR K+P +  GA     P++
Sbjct: 140 TIPAAQVALAKQLAGDIALELQAYFRSKFPELPFGAFVPGGPLY 183


>gi|10190704 2,4-dienoyl CoA reductase 2 [Homo sapiens]
          Length = 292

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 27/103 (26%), Positives = 46/103 (44%), Gaps = 12/103 (11%)

Query: 2   GRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTS----LPAVAKNYSVLYFQQKV 57
           GRR L L +     P    A+  AL+  G + +  N  +     PA A +++       +
Sbjct: 77  GRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDI 136

Query: 58  DHFGFNTVKTFNQRYLVADKYWKKNGGSILFYT---GNEGDII 97
           D  G     TFN   ++ +K+++ +GG I+  T   GN G  +
Sbjct: 137 DTSG-----TFNVSRVLYEKFFRDHGGVIVNITATLGNRGQAL 174


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.437 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,554,782
Number of Sequences: 37866
Number of extensions: 861822
Number of successful extensions: 1740
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1722
Number of HSP's gapped (non-prelim): 10
length of query: 496
length of database: 18,247,518
effective HSP length: 106
effective length of query: 390
effective length of database: 14,233,722
effective search space: 5551151580
effective search space used: 5551151580
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.