Search of human proteins with 4759240

Search of human proteins with 4759240

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4759240 transmembrane 4 superfamily member 4 [Homo sapiens]
         (202 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4759240 transmembrane 4 superfamily member 4 [Homo sapiens]        438   e-123
gi|21265101 transmembrane 4 superfamily member 1 [Homo sapiens]       223   1e-58
gi|21265113 transmembrane 4 superfamily member 5 [Homo sapiens]       169   1e-42
gi|20270327 transmembrane 4 L six family member 18 [Homo sapiens]     152   2e-37
gi|115511028 transmembrane 4 L six family member 19 [Homo sapiens]     91   9e-19
gi|188528611 transmembrane 4 L six family member 20 [Homo sapiens]     55   4e-08
gi|24041012 kringle-containing transmembrane protein 1 isoform 2...    28   4.1  
gi|227116325 kringle-containing transmembrane protein 1 isoform ...    28   4.1  
gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]                    27   9.0  
gi|51093859 calcium channel, voltage-dependent, T type, alpha 1I...    27   9.0  
gi|21361077 calcium channel, voltage-dependent, T type, alpha 1I...    27   9.0  

>gi|4759240 transmembrane 4 superfamily member 4 [Homo sapiens]
          Length = 202

 Score =  438 bits (1127), Expect = e-123
 Identities = 202/202 (100%), Positives = 202/202 (100%)

Query: 1   MCTGGCARCLGGTLIPLAFFGFLANILLFFPGGKVIDDNDHLSQEIWFFGGILGSGVLMI 60
           MCTGGCARCLGGTLIPLAFFGFLANILLFFPGGKVIDDNDHLSQEIWFFGGILGSGVLMI
Sbjct: 1   MCTGGCARCLGGTLIPLAFFGFLANILLFFPGGKVIDDNDHLSQEIWFFGGILGSGVLMI 60

Query: 61  FPALVFLGLKNNDCCGCCGNEGCGKRFAMFTSTIFAVVGFLGAGYSFIISAISINKGPKC 120
           FPALVFLGLKNNDCCGCCGNEGCGKRFAMFTSTIFAVVGFLGAGYSFIISAISINKGPKC
Sbjct: 61  FPALVFLGLKNNDCCGCCGNEGCGKRFAMFTSTIFAVVGFLGAGYSFIISAISINKGPKC 120

Query: 121 LMANSTWGYPFHDGDYLNDEALWNKCREPLNVVPWNLTLFSILLVVGGIQMVLCAIQVVN 180
           LMANSTWGYPFHDGDYLNDEALWNKCREPLNVVPWNLTLFSILLVVGGIQMVLCAIQVVN
Sbjct: 121 LMANSTWGYPFHDGDYLNDEALWNKCREPLNVVPWNLTLFSILLVVGGIQMVLCAIQVVN 180

Query: 181 GLLGTLCGDCQCCGCCGGDGPV 202
           GLLGTLCGDCQCCGCCGGDGPV
Sbjct: 181 GLLGTLCGDCQCCGCCGGDGPV 202


>gi|21265101 transmembrane 4 superfamily member 1 [Homo sapiens]
          Length = 202

 Score =  223 bits (567), Expect = 1e-58
 Identities = 98/193 (50%), Positives = 138/193 (71%), Gaps = 3/193 (1%)

Query: 1   MCTGGCARCLGGTLIPLAFFGFLANILLFFPGGKV-IDDNDHLSQEIWFFGGILGSGVLM 59
           MC G CARC+G +L+ LA     ANILL+FP G+      +HLS+ +WFF GI+G G+LM
Sbjct: 1   MCYGKCARCIGHSLVGLALLCIAANILLYFPNGETKYASENHLSRFVWFFSGIVGGGLLM 60

Query: 60  IFPALVFLGLKNNDCCGCCGNEGCGKRFAMFTSTIFAVVGFLGAGYSFIISAISINKGPK 119
           + PA VF+GL+ +DCCGCCG+E CGKR AM +S + A++G  G+GY  I++A+ + +GP 
Sbjct: 61  LLPAFVFIGLEQDDCCGCCGHENCGKRCAMLSSVLAALIGIAGSGYCVIVAALGLAEGPL 120

Query: 120 CLMANSTWGYPF--HDGDYLNDEALWNKCREPLNVVPWNLTLFSILLVVGGIQMVLCAIQ 177
           CL +   W Y F   +G YL D + W++C EP ++V WN++LFSILL +GGI+ +LC IQ
Sbjct: 121 CLDSLGQWNYTFASTEGQYLLDTSTWSECTEPKHIVEWNVSLFSILLALGGIEFILCLIQ 180

Query: 178 VVNGLLGTLCGDC 190
           V+NG+LG +CG C
Sbjct: 181 VINGVLGGICGFC 193


>gi|21265113 transmembrane 4 superfamily member 5 [Homo sapiens]
          Length = 197

 Score =  169 bits (428), Expect = 1e-42
 Identities = 84/196 (42%), Positives = 114/196 (58%), Gaps = 11/196 (5%)

Query: 1   MCTGGCARCLGGTLIPLAFFGFLANILLFFPGGKVIDDN-DHLSQEIWFFGGILGSGVLM 59
           MCTG CARC+G +LI L     +AN LL  P G+    N +HLS ++W  GG +G G+++
Sbjct: 1   MCTGKCARCVGLSLITLCLVCIVANALLLVPNGETSWTNTNHLSLQVWLMGGFIGGGLMV 60

Query: 60  IFPALVFLGLKNNDCCG--CCGNEGCGKRFAMFTSTIFAVVGFLGAGYSFIISAISINKG 117
           + P +  +      CCG  CCGN     R  M  S   +  G LGA Y   +S   +  G
Sbjct: 61  LCPGIAAVRAGGKGCCGAGCCGN-----RCRMLRSVFSSAFGVLGAIYCLSVSGAGLRNG 115

Query: 118 PKCLMANSTWGYPFHD--GDYLNDEALWNKCREPLNVVPWNLTLFSILLVVGGIQMVLCA 175
           P+CLM N  WGY F D  G YL +  LW++C  P  VVPWN+TLFS+L+    +++VLC 
Sbjct: 116 PRCLM-NGEWGYHFEDTAGAYLLNRTLWDRCEAPPRVVPWNVTLFSLLVAASCLEIVLCG 174

Query: 176 IQVVNGLLGTLCGDCQ 191
           IQ+VN  +G  CGDC+
Sbjct: 175 IQLVNATIGVFCGDCR 190


>gi|20270327 transmembrane 4 L six family member 18 [Homo sapiens]
          Length = 201

 Score =  152 bits (384), Expect = 2e-37
 Identities = 76/188 (40%), Positives = 114/188 (60%), Gaps = 7/188 (3%)

Query: 4   GGCARCLGGTLIPLAFFGFLANILLFFPGGKV-IDDNDHLSQEIWFFGGILGSGVLMIFP 62
           GGC  CL   LIPLA +  + NILL+FP G+     ++ L+  +W+F GI  SG++M+  
Sbjct: 7   GGCLSCL---LIPLALWSIIVNILLYFPNGQTSYASSNKLTNYVWYFEGICFSGIMMLIV 63

Query: 63  ALVFLGLKNNDCCGCCGNEGCGKRFAMFTSTIFAVVGFLGAGYSFIISAISINKGPKCLM 122
             V L L+NN+   CC +E C K++    S IF+ +G   +GY  +ISA+ + +GP C  
Sbjct: 64  TTVLLVLENNNNYKCCQSENCSKKYVTLLSIIFSSLGIAFSGYCLVISALGLVQGPYCRT 123

Query: 123 ANSTWGYPFHD--GDYLNDEALWNKCREPLNVVPWNLTLFSILLVVGGIQMVLCAIQVVN 180
            +  W Y F    G +L D ++W +C EP +VV WN+ LFSIL+ + G+Q+++C I+VV 
Sbjct: 124 LDG-WEYAFEGTAGRFLTDSSIWIQCLEPAHVVEWNIILFSILITLSGLQVIICLIRVVM 182

Query: 181 GLLGTLCG 188
            L   LCG
Sbjct: 183 QLSKILCG 190


>gi|115511028 transmembrane 4 L six family member 19 [Homo sapiens]
          Length = 209

 Score = 90.5 bits (223), Expect = 9e-19
 Identities = 63/198 (31%), Positives = 94/198 (47%), Gaps = 15/198 (7%)

Query: 6   CARCLGGTLIPLAFFGFLANILLFFPGGKVIDDNDHLSQEIWFFGGILGSGVLMIFPALV 65
           C+R LG +L   A F   AN+ L  P   V      L       G  L  G LM+  A +
Sbjct: 14  CSRILGLSLGTAALFAAGANVALLLPNWDVTYLLRGLLGRHAMLGTGLWGGGLMVLTAAI 73

Query: 66  FLGLKNNDCCGCCGNEGCGKRFAMFTSTIFAVVGFLGAGYSFIISAISINKGPKCLMANS 125
            + L      GC    G  +  ++ T+ +   +  LGA   F+ S +++  GP C+   S
Sbjct: 74  LISLMGWRY-GCFSKSGLCR--SVLTALLSGGLALLGALICFVTSGVALKDGPFCMFDVS 130

Query: 126 T--------WGYPF---HDGDYLNDEALWNK-CREPLNVVPWNLTLFSILLVVGGIQMVL 173
           +        +GYPF   H  +YL D +LWN  C EP   V W+++LFS LL +  +Q++L
Sbjct: 131 SFNQTQAWKYGYPFKDLHSRNYLYDRSLWNSVCLEPSAAVVWHVSLFSALLCISLLQLLL 190

Query: 174 CAIQVVNGLLGTLCGDCQ 191
             + V+N LLG  C  C+
Sbjct: 191 VVVHVINSLLGLFCSLCE 208


>gi|188528611 transmembrane 4 L six family member 20 [Homo sapiens]
          Length = 229

 Score = 55.1 bits (131), Expect = 4e-08
 Identities = 39/129 (30%), Positives = 60/129 (46%), Gaps = 18/129 (13%)

Query: 2   CTGGCARCLGGTLIPLAFFGFLANILLFFPGGKVIDDNDHLSQEI-----WFFGGILGSG 56
           C  G   C G +L+ L   G + N +        + + D  SQ       W+F GI+G+G
Sbjct: 3   CCEGWTSCNGFSLLVLLLLGVVLNAIPLIVS---LVEEDQFSQNPISCFEWWFPGIIGAG 59

Query: 57  VLMIFPALVFLGLKNNDCCGCCGNEGCGKRFAMFTSTIFAVVGFLGAGYSFIISAISINK 116
           ++ I    + L  +   CC          R  MF S++F+V+  +GA Y  +IS  ++ K
Sbjct: 60  LMAIPATTMSLTARKRACCN--------NRTGMFLSSLFSVITVIGALYCMLISIQALLK 111

Query: 117 GPKCLMANS 125
           GP  LM NS
Sbjct: 112 GP--LMCNS 118


>gi|24041012 kringle-containing transmembrane protein 1 isoform 2
           precursor [Homo sapiens]
          Length = 492

 Score = 28.5 bits (62), Expect = 4.1
 Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 4/58 (6%)

Query: 102 GAGYSFIISAISINKGPKCLMANSTWGYPFHDGDYLNDE---ALWNKCREP-LNVVPW 155
           GA Y    +  ++  G  CL  N T+ +P++   Y N E      N CR P  +V PW
Sbjct: 39  GADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDVSPW 96


>gi|227116325 kringle-containing transmembrane protein 1 isoform 3
           precursor [Homo sapiens]
          Length = 458

 Score = 28.5 bits (62), Expect = 4.1
 Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 4/58 (6%)

Query: 102 GAGYSFIISAISINKGPKCLMANSTWGYPFHDGDYLNDE---ALWNKCREP-LNVVPW 155
           GA Y    +  ++  G  CL  N T+ +P++   Y N E      N CR P  +V PW
Sbjct: 39  GADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDVSPW 96


>gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]
          Length = 207

 Score = 27.3 bits (59), Expect = 9.0
 Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 17/119 (14%)

Query: 89  MFTSTIFAVVGFLGAGYSFIISAISINKGPKCLMANS----TWGYPFHDGDYLNDEALWN 144
           M  + I+A+V  +G G+  +++A + N+      A+S    TW Y    G ++N      
Sbjct: 1   MSRAQIWALVSGVG-GFGALVAATTSNEWKVTTRASSVITATWVY---QGLWMNCAGYIQ 56

Query: 145 KCREPLNVVPWNLTLFSILLV--------VGGIQMVLCAIQVVNGLLGTLCGDCQCCGC 195
            CR  L +   +L  F  +          VGG       I  + G++  L G C   GC
Sbjct: 57  ACRG-LMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGC 114


>gi|51093859 calcium channel, voltage-dependent, T type, alpha 1I
            subunit isoform b [Homo sapiens]
          Length = 2188

 Score = 27.3 bits (59), Expect = 9.0
 Identities = 14/42 (33%), Positives = 21/42 (50%)

Query: 158  TLFSILLVVGGIQMVLCAIQVVNGLLGTLCGDCQCCGCCGGD 199
            TL S L  +G I ++ CA  ++ G+LG      +   C G D
Sbjct: 1263 TLISSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYHCLGVD 1304


>gi|21361077 calcium channel, voltage-dependent, T type, alpha 1I
            subunit isoform a [Homo sapiens]
          Length = 2223

 Score = 27.3 bits (59), Expect = 9.0
 Identities = 14/42 (33%), Positives = 21/42 (50%)

Query: 158  TLFSILLVVGGIQMVLCAIQVVNGLLGTLCGDCQCCGCCGGD 199
            TL S L  +G I ++ CA  ++ G+LG      +   C G D
Sbjct: 1298 TLISSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYHCLGVD 1339


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.330    0.149    0.522 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,827,853
Number of Sequences: 37866
Number of extensions: 379962
Number of successful extensions: 1223
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1200
Number of HSP's gapped (non-prelim): 15
length of query: 202
length of database: 18,247,518
effective HSP length: 97
effective length of query: 105
effective length of database: 14,574,516
effective search space: 1530324180
effective search space used: 1530324180
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.