Guide to the Human Genome
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Search of human proteins with 4758878

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4758878 platelet-activating factor acetylhydrolase 2 [Homo
sapiens]
         (392 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4758878 platelet-activating factor acetylhydrolase 2 [Homo sa...   808   0.0  
gi|189095271 phospholipase A2, group VII [Homo sapiens]               306   2e-83
gi|16933540 fibroblast activation protein, alpha subunit [Homo s...    33   0.34 
gi|194394146 dipeptidylpeptidase 9 [Homo sapiens]                      33   0.44 
gi|37577089 dipeptidyl peptidase 8 isoform 3 [Homo sapiens]            31   2.2  
gi|18450280 dipeptidyl peptidase 8 isoform 1 [Homo sapiens]            31   2.2  
gi|25282407 interferon-stimulated transcription factor 3, gamma ...    30   3.8  

>gi|4758878 platelet-activating factor acetylhydrolase 2 [Homo
           sapiens]
          Length = 392

 Score =  808 bits (2087), Expect = 0.0
 Identities = 392/392 (100%), Positives = 392/392 (100%)

Query: 1   MGVNQSVGFPPVTGPHLVGCGDVMEGQNLQGSFFRLFYPCQKAEETMEQPLWIPRYEYCT 60
           MGVNQSVGFPPVTGPHLVGCGDVMEGQNLQGSFFRLFYPCQKAEETMEQPLWIPRYEYCT
Sbjct: 1   MGVNQSVGFPPVTGPHLVGCGDVMEGQNLQGSFFRLFYPCQKAEETMEQPLWIPRYEYCT 60

Query: 61  GLAEYLQFNKRCGGLLFNLAVGSCRLPVSWNGPFKTKDSGYPLIIFSHGLGAFRTLYSAF 120
           GLAEYLQFNKRCGGLLFNLAVGSCRLPVSWNGPFKTKDSGYPLIIFSHGLGAFRTLYSAF
Sbjct: 61  GLAEYLQFNKRCGGLLFNLAVGSCRLPVSWNGPFKTKDSGYPLIIFSHGLGAFRTLYSAF 120

Query: 121 CMELASRGFVVAVPEHRDRSAATTYFCKQAPEENQPTNESLQEEWIPFRRVEEGEKEFHV 180
           CMELASRGFVVAVPEHRDRSAATTYFCKQAPEENQPTNESLQEEWIPFRRVEEGEKEFHV
Sbjct: 121 CMELASRGFVVAVPEHRDRSAATTYFCKQAPEENQPTNESLQEEWIPFRRVEEGEKEFHV 180

Query: 181 RNPQVHQRVSECLRVLKILQEVTAGQTVFNILPGGLDLMTLKGNIDMSRVAVMGHSFGGA 240
           RNPQVHQRVSECLRVLKILQEVTAGQTVFNILPGGLDLMTLKGNIDMSRVAVMGHSFGGA
Sbjct: 181 RNPQVHQRVSECLRVLKILQEVTAGQTVFNILPGGLDLMTLKGNIDMSRVAVMGHSFGGA 240

Query: 241 TAILALAKETQFRCAVALDAWMFPLERDFYPKARGPVFFINTEKFQTMESVNLMKKICAQ 300
           TAILALAKETQFRCAVALDAWMFPLERDFYPKARGPVFFINTEKFQTMESVNLMKKICAQ
Sbjct: 241 TAILALAKETQFRCAVALDAWMFPLERDFYPKARGPVFFINTEKFQTMESVNLMKKICAQ 300

Query: 301 HEQSRIITVLGSVHRSQTDFAFVTGNLIGKFFSTETRGSLDPYEGQEVMVRAMLAFLQKH 360
           HEQSRIITVLGSVHRSQTDFAFVTGNLIGKFFSTETRGSLDPYEGQEVMVRAMLAFLQKH
Sbjct: 301 HEQSRIITVLGSVHRSQTDFAFVTGNLIGKFFSTETRGSLDPYEGQEVMVRAMLAFLQKH 360

Query: 361 LDLKEDYNQWNNLIEGIGPSLTPGAPHHLSSL 392
           LDLKEDYNQWNNLIEGIGPSLTPGAPHHLSSL
Sbjct: 361 LDLKEDYNQWNNLIEGIGPSLTPGAPHHLSSL 392


>gi|189095271 phospholipase A2, group VII [Homo sapiens]
          Length = 441

 Score =  306 bits (784), Expect = 2e-83
 Identities = 163/375 (43%), Positives = 234/375 (62%), Gaps = 12/375 (3%)

Query: 10  PPVTGPHLVGCGDVMEGQNLQGSFFRLFYPCQKAEETMEQPLWIPRYEYCTGLAEYLQFN 69
           P   GP+ VGC D+M     +G+F RL+YP Q  +      LWIP  EY  GL+++L  +
Sbjct: 57  PRGNGPYSVGCTDLMFDHTNKGTFLRLYYPSQDNDRL--DTLWIPNKEYFWGLSKFLGTH 114

Query: 70  KRCGGLLFNLAVGSCRLPVSWNGPFKTKDSGYPLIIFSHGLGAFRTLYSAFCMELASRGF 129
              G +L  L  GS   P +WN P +  +  YPL++FSHGLGAFRTLYSA  ++LAS GF
Sbjct: 115 WLMGNIL-RLLFGSMTTPANWNSPLRPGEK-YPLVVFSHGLGAFRTLYSAIGIDLASHGF 172

Query: 130 VVAVPEHRDRSAATTYFCKQAPEENQPTNESLQEEWIPFRRVEEGEKEFHVRNPQVHQRV 189
           +VA  EHRDRSA+ TY+ K     +Q   E   + W+  R +++ E+E H+RN QV QR 
Sbjct: 173 IVAAVEHRDRSASATYYFK-----DQSAAEIGDKSWLYLRTLKQ-EEETHIRNEQVRQRA 226

Query: 190 SECLRVLKILQEVTAGQTVFNILPGGLDLMTLKGNIDMSRVAVMGHSFGGATAILALAKE 249
            EC + L ++ ++  G+ V N L    D+  LK +ID  ++AV+GHSFGGAT I  L+++
Sbjct: 227 KECSQALSLILDIDHGKPVKNALDLKFDMEQLKDSIDREKIAVIGHSFGGATVIQTLSED 286

Query: 250 TQFRCAVALDAWMFPLERDFYPKARGPVFFINTEKFQTMESVNLMKKICAQHEQSRIITV 309
            +FRC +ALDAWMFPL  + Y +   P+FFIN+E FQ   ++  MKK  +  ++ ++IT+
Sbjct: 287 QRFRCGIALDAWMFPLGDEVYSRIPQPLFFINSEYFQYPANIIKMKKCYSPDKERKMITI 346

Query: 310 LGSVHRSQTDFAFVTGNLIGKFFSTETRGSLDPYEGQEVMVRAMLAFLQKHLDLKEDYNQ 369
            GSVH++  DF F TG +IG     + +G +D     ++  +A LAFLQKHL L +D++Q
Sbjct: 347 RGSVHQNFADFTFATGKIIGHML--KLKGDIDSNVAIDLSNKASLAFLQKHLGLHKDFDQ 404

Query: 370 WNNLIEGIGPSLTPG 384
           W+ LIEG   +L PG
Sbjct: 405 WDCLIEGDDENLIPG 419


>gi|16933540 fibroblast activation protein, alpha subunit [Homo
           sapiens]
          Length = 760

 Score = 33.5 bits (75), Expect = 0.34
 Identities = 17/37 (45%), Positives = 24/37 (64%), Gaps = 1/37 (2%)

Query: 223 GNIDMSRVAVMGHSFGGATAILALAKET-QFRCAVAL 258
           G ID  R+A+ G S+GG  + LALA  T  F+C +A+
Sbjct: 611 GFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAV 647


>gi|194394146 dipeptidylpeptidase 9 [Homo sapiens]
          Length = 892

 Score = 33.1 bits (74), Expect = 0.44
 Identities = 21/53 (39%), Positives = 32/53 (60%), Gaps = 5/53 (9%)

Query: 215 GLDLMTLK-GNIDMSRVAVMGHSFGGATAILALAKETQ-FRCAVA---LDAWM 262
           GL  +  K G ID+SRVA+ G S+GG  +++ L  + Q F+ A+A   +  WM
Sbjct: 737 GLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWM 789


>gi|37577089 dipeptidyl peptidase 8 isoform 3 [Homo sapiens]
          Length = 898

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 16/43 (37%), Positives = 27/43 (62%), Gaps = 4/43 (9%)

Query: 225 IDMSRVAVMGHSFGGATAILALAKETQ-FRCAVA---LDAWMF 263
           ID+ RV + G S+GG  +++AL + +  FR A+A   +  W+F
Sbjct: 744 IDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIF 786


>gi|18450280 dipeptidyl peptidase 8 isoform 1 [Homo sapiens]
          Length = 882

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 16/43 (37%), Positives = 27/43 (62%), Gaps = 4/43 (9%)

Query: 225 IDMSRVAVMGHSFGGATAILALAKETQ-FRCAVA---LDAWMF 263
           ID+ RV + G S+GG  +++AL + +  FR A+A   +  W+F
Sbjct: 728 IDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIF 770


>gi|25282407 interferon-stimulated transcription factor 3, gamma
           48kDa [Homo sapiens]
          Length = 393

 Score = 30.0 bits (66), Expect = 3.8
 Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 2/41 (4%)

Query: 84  CRLPVSWNGPFKTKDSGYPLIIFSHGLGAFRTLYSAFCMEL 124
           C +P+SWN P      G  L+  +  +  FRT Y  FC +L
Sbjct: 294 CPIPISWNAPQAPPGPGPHLLPSNECVELFRTAY--FCRDL 332


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,730,125
Number of Sequences: 37866
Number of extensions: 682726
Number of successful extensions: 1304
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1295
Number of HSP's gapped (non-prelim): 7
length of query: 392
length of database: 18,247,518
effective HSP length: 104
effective length of query: 288
effective length of database: 14,309,454
effective search space: 4121122752
effective search space used: 4121122752
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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