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Search of human proteins with 4758368
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758368 fibroblast growth factor 14 isoform 1A [Homo
sapiens]
(247 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758368 fibroblast growth factor 14 isoform 1A [Homo sapiens] 501 e-142
gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens] 377 e-105
gi|11136630 fibroblast growth factor 12 isoform 1 [Homo sapiens] 350 5e-97
gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens] 340 5e-94
gi|21614511 fibroblast growth factor 12 isoform 2 [Homo sapiens] 286 1e-77
gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens] 279 1e-75
gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens] 279 1e-75
gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens] 279 1e-75
gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens] 279 2e-75
gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens] 278 4e-75
gi|4758362 fibroblast growth factor 11 [Homo sapiens] 273 1e-73
gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens] 125 3e-29
gi|9789947 fibroblast growth factor 20 [Homo sapiens] 123 1e-28
gi|4503691 fibroblast growth factor 16 [Homo sapiens] 120 1e-27
gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo... 98 6e-21
gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens] 97 1e-20
gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens] 96 4e-20
gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens] 92 3e-19
gi|10190672 fibroblast growth factor 22 precursor [Homo sapiens] 88 8e-18
gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens] 87 1e-17
gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens] 86 2e-17
gi|222144221 fibroblast growth factor 1 (acidic) isoform 1 propr... 84 1e-16
gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprot... 84 1e-16
gi|222144273 fibroblast growth factor 1 (acidic) isoform 1 propr... 84 1e-16
gi|222144271 fibroblast growth factor 1 (acidic) isoform 1 propr... 84 1e-16
gi|153285461 fibroblast growth factor 2 [Homo sapiens] 74 9e-14
gi|9506597 fibroblast growth factor 21 precursor [Homo sapiens] 55 6e-08
gi|10190674 fibroblast growth factor 23 precursor [Homo sapiens] 50 1e-06
gi|15147350 fibroblast growth factor 8 isoform A precursor [Homo... 49 4e-06
gi|5174439 fibroblast growth factor 8 isoform B precursor [Homo ... 49 4e-06
>gi|4758368 fibroblast growth factor 14 isoform 1A [Homo sapiens]
Length = 247
Score = 501 bits (1289), Expect = e-142
Identities = 247/247 (100%), Positives = 247/247 (100%)
Query: 1 MAAAIASGLIRQKRQAREQHWDRPSASRRRSSPSKNRGLCNGNLVDIFSKVRIFGLKKRR 60
MAAAIASGLIRQKRQAREQHWDRPSASRRRSSPSKNRGLCNGNLVDIFSKVRIFGLKKRR
Sbjct: 1 MAAAIASGLIRQKRQAREQHWDRPSASRRRSSPSKNRGLCNGNLVDIFSKVRIFGLKKRR 60
Query: 61 LRRQDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVK 120
LRRQDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVK
Sbjct: 61 LRRQDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVK 120
Query: 121 TGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQ 180
TGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQ
Sbjct: 121 TGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQ 180
Query: 181 AMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKP 240
AMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKP
Sbjct: 181 AMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKP 240
Query: 241 VNKSKTT 247
VNKSKTT
Sbjct: 241 VNKSKTT 247
>gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens]
Length = 252
Score = 377 bits (967), Expect = e-105
Identities = 184/190 (96%), Positives = 185/190 (97%)
Query: 58 KRRLRRQDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQ 117
K+ DPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQ
Sbjct: 63 KKNKNPTDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQ 122
Query: 118 GVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNK 177
GVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNK
Sbjct: 123 GVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNK 182
Query: 178 EGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNG 237
EGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNG
Sbjct: 183 EGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNG 242
Query: 238 GKPVNKSKTT 247
GKPVNKSKTT
Sbjct: 243 GKPVNKSKTT 252
>gi|11136630 fibroblast growth factor 12 isoform 1 [Homo sapiens]
Length = 243
Score = 350 bits (899), Expect = 5e-97
Identities = 178/248 (71%), Positives = 210/248 (84%), Gaps = 7/248 (2%)
Query: 1 MAAAIASGLIRQKRQAREQHWDRPSASRRRSSPSKN-RGLCNGNLVDIFSKVRIFGLKKR 59
MAAAIAS LIRQKRQARE + DR SAS+RRSSPSK+ R LC +++ +FSKVR +KR
Sbjct: 1 MAAAIASSLIRQKRQARESNSDRVSASKRRSSPSKDGRSLCERHVLGVFSKVRFCSGRKR 60
Query: 60 RLRRQ-DPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQG 118
+RR+ +PQLKGIVTRL+ +QGY+LQMHPDG +DGTKD++++ TLFNLIPVGLRVVAIQG
Sbjct: 61 PVRRRPEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQG 120
Query: 119 VKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKE 178
VK LY+AMNGEGYLY S++FTPECKFKESVFENYYVIYSS LYRQQESGRAWFLGLNKE
Sbjct: 121 VKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKE 180
Query: 179 GQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGG 238
GQ MKGNRVKKTKP++HF+PKP+EV MYREPSLH++GE K G S+ +S + MNGG
Sbjct: 181 GQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGE---KQG--RSRKSSGTPTMNGG 235
Query: 239 KPVNKSKT 246
K VN+ T
Sbjct: 236 KVVNQDST 243
>gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens]
Length = 245
Score = 340 bits (873), Expect = 5e-94
Identities = 167/247 (67%), Positives = 204/247 (82%), Gaps = 2/247 (0%)
Query: 1 MAAAIASGLIRQKRQAREQHWDRPSASRRRSSPSKNRGLCNGNLVDIFSKVRIFGLKKRR 60
MAAAIAS LIRQKRQARE+ ++ +A + SSPSK + C+ N +++FS+V++FG KKRR
Sbjct: 1 MAAAIASSLIRQKRQARER--EKSNACKCVSSPSKGKTSCDKNKLNVFSRVKLFGSKKRR 58
Query: 61 LRRQDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVK 120
RR +PQLKGIVT+LY RQGY+LQ+ DG +DGTKD+ + TLFNLIPVGLRVVAIQGV+
Sbjct: 59 RRRPEPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQ 118
Query: 121 TGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQ 180
T LY+AMN EGYLY SELFTPECKFKESVFENYYV YSSM+YRQQ+SGR W+LGLNKEG+
Sbjct: 119 TKLYLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGE 178
Query: 181 AMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKP 240
MKGN VKK KPAAHFLPKPL+VAMY+EPSLHD+ E TP+KS S S ++NGGK
Sbjct: 179 IMKGNHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNGGKS 238
Query: 241 VNKSKTT 247
++ +++T
Sbjct: 239 MSHNEST 245
>gi|21614511 fibroblast growth factor 12 isoform 2 [Homo sapiens]
Length = 181
Score = 286 bits (732), Expect = 1e-77
Identities = 137/186 (73%), Positives = 161/186 (86%), Gaps = 5/186 (2%)
Query: 61 LRRQDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVK 120
+ ++PQLKGIVTRL+ +QGY+LQMHPDG +DGTKD++++ TLFNLIPVGLRVVAIQGVK
Sbjct: 1 MESKEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVK 60
Query: 121 TGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQ 180
LY+AMNGEGYLY S++FTPECKFKESVFENYYVIYSS LYRQQESGRAWFLGLNKEGQ
Sbjct: 61 ASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQ 120
Query: 181 AMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKP 240
MKGNRVKKTKP++HF+PKP+EV MYREPSLH++GE K G S+ +S + MNGGK
Sbjct: 121 IMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGE---KQG--RSRKSSGTPTMNGGKV 175
Query: 241 VNKSKT 246
VN+ T
Sbjct: 176 VNQDST 181
>gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens]
Length = 226
Score = 279 bits (714), Expect = 1e-75
Identities = 132/190 (69%), Positives = 157/190 (82%)
Query: 58 KRRLRRQDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQ 117
K ++PQLKGIVT+LY RQGY+LQ+ DG +DGTKD+ + TLFNLIPVGLRVVAIQ
Sbjct: 37 KENTEPEEPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQ 96
Query: 118 GVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNK 177
GV+T LY+AMN EGYLY SELFTPECKFKESVFENYYV YSSM+YRQQ+SGR W+LGLNK
Sbjct: 97 GVQTKLYLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNK 156
Query: 178 EGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNG 237
EG+ MKGN VKK KPAAHFLPKPL+VAMY+EPSLHD+ E TP+KS S S ++NG
Sbjct: 157 EGEIMKGNHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNG 216
Query: 238 GKPVNKSKTT 247
GK ++ +++T
Sbjct: 217 GKSMSHNEST 226
>gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens]
Length = 226
Score = 279 bits (714), Expect = 1e-75
Identities = 132/190 (69%), Positives = 157/190 (82%)
Query: 58 KRRLRRQDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQ 117
K ++PQLKGIVT+LY RQGY+LQ+ DG +DGTKD+ + TLFNLIPVGLRVVAIQ
Sbjct: 37 KENTEPEEPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQ 96
Query: 118 GVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNK 177
GV+T LY+AMN EGYLY SELFTPECKFKESVFENYYV YSSM+YRQQ+SGR W+LGLNK
Sbjct: 97 GVQTKLYLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNK 156
Query: 178 EGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNG 237
EG+ MKGN VKK KPAAHFLPKPL+VAMY+EPSLHD+ E TP+KS S S ++NG
Sbjct: 157 EGEIMKGNHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNG 216
Query: 238 GKPVNKSKTT 247
GK ++ +++T
Sbjct: 217 GKSMSHNEST 226
>gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens]
Length = 255
Score = 279 bits (714), Expect = 1e-75
Identities = 132/190 (69%), Positives = 157/190 (82%)
Query: 58 KRRLRRQDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQ 117
K ++PQLKGIVT+LY RQGY+LQ+ DG +DGTKD+ + TLFNLIPVGLRVVAIQ
Sbjct: 66 KENTEPEEPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQ 125
Query: 118 GVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNK 177
GV+T LY+AMN EGYLY SELFTPECKFKESVFENYYV YSSM+YRQQ+SGR W+LGLNK
Sbjct: 126 GVQTKLYLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNK 185
Query: 178 EGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNG 237
EG+ MKGN VKK KPAAHFLPKPL+VAMY+EPSLHD+ E TP+KS S S ++NG
Sbjct: 186 EGEIMKGNHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNG 245
Query: 238 GKPVNKSKTT 247
GK ++ +++T
Sbjct: 246 GKSMSHNEST 255
>gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens]
Length = 199
Score = 279 bits (713), Expect = 2e-75
Identities = 132/191 (69%), Positives = 159/191 (83%)
Query: 57 KKRRLRRQDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAI 116
K+ + ++PQLKGIVT+LY RQGY+LQ+ DG +DGTKD+ + TLFNLIPVGLRVVAI
Sbjct: 9 KEEKDASKEPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAI 68
Query: 117 QGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLN 176
QGV+T LY+AMN EGYLY SELFTPECKFKESVFENYYV YSSM+YRQQ+SGR W+LGLN
Sbjct: 69 QGVQTKLYLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLN 128
Query: 177 KEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMN 236
KEG+ MKGN VKK KPAAHFLPKPL+VAMY+EPSLHD+ E TP+KS S S ++N
Sbjct: 129 KEGEIMKGNHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLN 188
Query: 237 GGKPVNKSKTT 247
GGK ++ +++T
Sbjct: 189 GGKSMSHNEST 199
>gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens]
Length = 192
Score = 278 bits (710), Expect = 4e-75
Identities = 131/183 (71%), Positives = 155/183 (84%)
Query: 65 DPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLY 124
+PQLKGIVT+LY RQGY+LQ+ DG +DGTKD+ + TLFNLIPVGLRVVAIQGV+T LY
Sbjct: 10 EPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLY 69
Query: 125 IAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKG 184
+AMN EGYLY SELFTPECKFKESVFENYYV YSSM+YRQQ+SGR W+LGLNKEG+ MKG
Sbjct: 70 LAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKG 129
Query: 185 NRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKPVNKS 244
N VKK KPAAHFLPKPL+VAMY+EPSLHD+ E TP+KS S S ++NGGK ++ +
Sbjct: 130 NHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNGGKSMSHN 189
Query: 245 KTT 247
++T
Sbjct: 190 EST 192
>gi|4758362 fibroblast growth factor 11 [Homo sapiens]
Length = 225
Score = 273 bits (698), Expect = 1e-73
Identities = 138/224 (61%), Positives = 167/224 (74%), Gaps = 1/224 (0%)
Query: 3 AAIASGLIRQKRQAREQHWDRPSASRRRSSPSKNRGLCNGNLVDIFSKVRIFGLKKRRLR 62
AA+AS LIRQKR+ RE RP +++RR P + LC L+ + SKVR+ G + R
Sbjct: 2 AALASSLIRQKREVREPGGSRPVSAQRRVCPRGTKSLCQKQLLILLSKVRLCGGRPARPD 61
Query: 63 R-QDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKT 121
R +PQLKGIVT+L+CRQG+YLQ +PDG++ GT +D+++ T FNLIPVGLRVV IQ K
Sbjct: 62 RGPEPQLKGIVTKLFCRQGFYLQANPDGSIQGTPEDTSSFTHFNLIPVGLRVVTIQSAKL 121
Query: 122 GLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQA 181
G Y+AMN EG LY S FT EC+FKE VFENYYV+Y+S LYRQ+ SGRAW+LGL+KEGQ
Sbjct: 122 GHYMAMNAEGLLYSSPHFTAECRFKECVFENYYVLYASALYRQRRSGRAWYLGLDKEGQV 181
Query: 182 MKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTP 225
MKGNRVKKTK AAHFLPK LEVAMY+EPSLH V E P P
Sbjct: 182 MKGNRVKKTKAAAHFLPKLLEVAMYQEPSLHSVPEASPSSPPAP 225
>gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens]
Length = 208
Score = 125 bits (315), Expect = 3e-29
Identities = 58/137 (42%), Positives = 91/137 (66%), Gaps = 2/137 (1%)
Query: 68 LKGIVTR--LYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYI 125
LKGI+ R LYCR G++L++ P+G + GT+ D + + I + + +V+I+GV +GLY+
Sbjct: 57 LKGILRRRQLYCRTGFHLEIFPNGTIQGTRKDHSRFGILEFISIAVGLVSIRGVDSGLYL 116
Query: 126 AMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGN 185
MN +G LY SE T EC F+E EN+Y YSS LY+ ++GR +++ LNK+G +G
Sbjct: 117 GMNEKGELYGSEKLTQECVFREQFEENWYNTYSSNLYKHVDTGRRYYVALNKDGTPREGT 176
Query: 186 RVKKTKPAAHFLPKPLE 202
R K+ + HFLP+P++
Sbjct: 177 RTKRHQKFTHFLPRPVD 193
>gi|9789947 fibroblast growth factor 20 [Homo sapiens]
Length = 211
Score = 123 bits (309), Expect = 1e-28
Identities = 60/137 (43%), Positives = 90/137 (65%), Gaps = 2/137 (1%)
Query: 68 LKGIVTR--LYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYI 125
L GI+ R LYCR G++LQ+ PDG++ GT+ D + + I V + +V+I+GV +GLY+
Sbjct: 60 LHGILRRRQLYCRTGFHLQILPDGSVQGTRQDHSLFGILEFISVAVGLVSIRGVDSGLYL 119
Query: 126 AMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGN 185
MN +G LY SE T EC F+E EN+Y YSS +Y+ ++GR +F+ LNK+G G
Sbjct: 120 GMNDKGELYGSEKLTSECIFREQFEENWYNTYSSNIYKHGDTGRRYFVALNKDGTPRDGA 179
Query: 186 RVKKTKPAAHFLPKPLE 202
R K+ + HFLP+P++
Sbjct: 180 RSKRHQKFTHFLPRPVD 196
>gi|4503691 fibroblast growth factor 16 [Homo sapiens]
Length = 207
Score = 120 bits (300), Expect = 1e-27
Identities = 58/149 (38%), Positives = 94/149 (63%), Gaps = 6/149 (4%)
Query: 60 RLRRQDP----QLKGIVTR--LYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRV 113
+L+R P LKGI+ R LYCR G++L++ P+G + GT+ D + + I + + +
Sbjct: 44 KLQRGSPTDFAHLKGILRRRQLYCRTGFHLEIFPNGTVHGTRHDHSRFGILEFISLAVGL 103
Query: 114 VAIQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFL 173
++I+GV +GLY+ MN G LY S+ T EC F+E EN+Y Y+S LY+ +S R +++
Sbjct: 104 ISIRGVDSGLYLGMNERGELYGSKKLTRECVFREQFEENWYNTYASTLYKHSDSERQYYV 163
Query: 174 GLNKEGQAMKGNRVKKTKPAAHFLPKPLE 202
LNK+G +G R K+ + HFLP+P++
Sbjct: 164 ALNKDGSPREGYRTKRHQKFTHFLPRPVD 192
>gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo
sapiens]
Length = 268
Score = 98.2 bits (243), Expect = 6e-21
Identities = 51/129 (39%), Positives = 83/129 (64%), Gaps = 5/129 (3%)
Query: 75 LYCRQG--YYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGY 132
LYCR G ++LQ++PDG ++G+ + + S L + V +V I+GV + ++AM+ +G
Sbjct: 91 LYCRVGIGFHLQIYPDGKVNGSHEANMLSVL-EIFAVSQGIVGIRGVFSNKFLAMSKKGK 149
Query: 133 LYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKG--NRVKKT 190
L+ S FT +CKF+E EN Y Y+S ++R +++GR W++ LNK G+A +G RVK
Sbjct: 150 LHASAKFTDDCKFRERFQENSYNTYASAIHRTEKTGREWYVALNKRGKAKRGCSPRVKPQ 209
Query: 191 KPAAHFLPK 199
+ HFLP+
Sbjct: 210 HISTHFLPR 218
>gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens]
Length = 239
Score = 97.1 bits (240), Expect = 1e-20
Identities = 50/139 (35%), Positives = 85/139 (61%), Gaps = 11/139 (7%)
Query: 74 RLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYL 133
+LYC Y+LQ+HP G ++G+ ++S S L + V + +VAI+G+ +G Y+AMN G L
Sbjct: 47 KLYCATKYHLQLHPSGRVNGSLENSAYSIL-EITAVEVGIVAIRGLFSGRYLAMNKRGRL 105
Query: 134 YPSELFTPECKFKESVFENYYVIYSSMLY----------RQQESGRAWFLGLNKEGQAMK 183
Y SE ++ EC+F E + E Y Y+S LY RQ + R W++ +N +G+ +
Sbjct: 106 YASEHYSAECEFVERIHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVNGKGRPRR 165
Query: 184 GNRVKKTKPAAHFLPKPLE 202
G + ++T+ ++ FLP+ L+
Sbjct: 166 GFKTRRTQKSSLFLPRVLD 184
>gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens]
Length = 194
Score = 95.5 bits (236), Expect = 4e-20
Identities = 47/127 (37%), Positives = 76/127 (59%), Gaps = 2/127 (1%)
Query: 72 VTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEG 131
V RL+CR +YL++ G + GT++ N + + V + +VAI+GV++ Y+AMN EG
Sbjct: 66 VRRLFCRTQWYLRIDKRGKVKGTQEMKNNYNIMEIRTVAVGIVAIKGVESEFYLAMNKEG 125
Query: 132 YLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTK 191
LY + +C FKE + EN+Y Y+S + +G F+ LN++G ++G + KK +
Sbjct: 126 KLYAKKECNEDCNFKELILENHYNTYASA--KWTHNGGEMFVALNQKGIPVRGKKTKKEQ 183
Query: 192 PAAHFLP 198
AHFLP
Sbjct: 184 KTAHFLP 190
>gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens]
Length = 206
Score = 92.4 bits (228), Expect = 3e-19
Identities = 54/128 (42%), Positives = 69/128 (53%), Gaps = 9/128 (7%)
Query: 74 RLYCRQG--YYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEG 131
RLYC G ++LQ PDG + G D T +L L PV VV+I GV + ++AM+ +G
Sbjct: 85 RLYCNVGIGFHLQALPDGRIGGAHAD-TRDSLLELSPVERGVVSIFGVASRFFVAMSSKG 143
Query: 132 YLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTK 191
LY S FT EC FKE + N Y Y S Y F+ L+K G+ KGNRV T
Sbjct: 144 KLYGSPFFTDECTFKEILLPNNYNAYESYKY------PGMFIALSKNGKTKKGNRVSPTM 197
Query: 192 PAAHFLPK 199
HFLP+
Sbjct: 198 KVTHFLPR 205
>gi|10190672 fibroblast growth factor 22 precursor [Homo sapiens]
Length = 170
Score = 87.8 bits (216), Expect = 8e-18
Identities = 48/138 (34%), Positives = 79/138 (57%), Gaps = 4/138 (2%)
Query: 63 RQDPQLKGIVT--RLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVK 120
R P L+G V RL+ ++L++ P G + GT+ ++ + V + VV I+ V
Sbjct: 31 RSYPHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVS 90
Query: 121 TGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQ 180
+G Y+AMN G LY S L+T +C+F+E + EN + Y+S +R++ G+ FL L++ G
Sbjct: 91 SGFYVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRRR--GQPMFLALDRRGG 148
Query: 181 AMKGNRVKKTKPAAHFLP 198
G R ++ +AHFLP
Sbjct: 149 PRPGGRTRRYHLSAHFLP 166
>gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens]
Length = 208
Score = 87.0 bits (214), Expect = 1e-17
Identities = 47/128 (36%), Positives = 75/128 (58%), Gaps = 9/128 (7%)
Query: 74 RLYCRQG--YYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEG 131
RLYC G ++LQ+ PDG + GT +++ S L + V VV++ GV++ L++AMN +G
Sbjct: 87 RLYCNVGIGFHLQVLPDGRISGTHEENPYS-LLEISTVERGVVSLFGVRSALFVAMNSKG 145
Query: 132 YLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTK 191
LY + F ECKF+E++ N Y Y S LY + ++ L+K G+ +G++V
Sbjct: 146 RLYATPSFQEECKFRETLLPNNYNAYESDLY------QGTYIALSKYGRVKRGSKVSPIM 199
Query: 192 PAAHFLPK 199
HFLP+
Sbjct: 200 TVTHFLPR 207
>gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens]
Length = 208
Score = 86.3 bits (212), Expect = 2e-17
Identities = 41/125 (32%), Positives = 74/125 (59%), Gaps = 2/125 (1%)
Query: 74 RLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYL 133
+L+ Y+L++ +G + GTK ++ ++ + V + VVA++ + + Y+AMN +G L
Sbjct: 81 KLFSFTKYFLKIEKNGKVSGTKKENCPYSILEITSVEIGVVAVKAINSNYYLAMNKKGKL 140
Query: 134 YPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPA 193
Y S+ F +CK KE + EN Y Y+S + Q +GR ++ LN +G +G + ++ +
Sbjct: 141 YGSKEFNNDCKLKERIEENGYNTYAS--FNWQHNGRQMYVALNGKGAPRRGQKTRRKNTS 198
Query: 194 AHFLP 198
AHFLP
Sbjct: 199 AHFLP 203
>gi|222144221 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 83.6 bits (205), Expect = 1e-16
Identities = 47/128 (36%), Positives = 70/128 (54%), Gaps = 5/128 (3%)
Query: 75 LYCRQG-YYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYL 133
LYC G ++L++ PDG +DGT+D S L + V I+ +TG Y+AM+ +G L
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLL 88
Query: 134 YPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPA 193
Y S+ EC F E + EN+Y Y S ++ + + WF+GL K G +G R + A
Sbjct: 89 YGSQTPNEECLFLERLEENHYNTYIS----KKHAEKNWFVGLKKNGSCKRGPRTHYGQKA 144
Query: 194 AHFLPKPL 201
FLP P+
Sbjct: 145 ILFLPLPV 152
>gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprotein
[Homo sapiens]
Length = 155
Score = 83.6 bits (205), Expect = 1e-16
Identities = 47/128 (36%), Positives = 70/128 (54%), Gaps = 5/128 (3%)
Query: 75 LYCRQG-YYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYL 133
LYC G ++L++ PDG +DGT+D S L + V I+ +TG Y+AM+ +G L
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLL 88
Query: 134 YPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPA 193
Y S+ EC F E + EN+Y Y S ++ + + WF+GL K G +G R + A
Sbjct: 89 YGSQTPNEECLFLERLEENHYNTYIS----KKHAEKNWFVGLKKNGSCKRGPRTHYGQKA 144
Query: 194 AHFLPKPL 201
FLP P+
Sbjct: 145 ILFLPLPV 152
>gi|222144273 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 83.6 bits (205), Expect = 1e-16
Identities = 47/128 (36%), Positives = 70/128 (54%), Gaps = 5/128 (3%)
Query: 75 LYCRQG-YYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYL 133
LYC G ++L++ PDG +DGT+D S L + V I+ +TG Y+AM+ +G L
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLL 88
Query: 134 YPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPA 193
Y S+ EC F E + EN+Y Y S ++ + + WF+GL K G +G R + A
Sbjct: 89 YGSQTPNEECLFLERLEENHYNTYIS----KKHAEKNWFVGLKKNGSCKRGPRTHYGQKA 144
Query: 194 AHFLPKPL 201
FLP P+
Sbjct: 145 ILFLPLPV 152
>gi|222144271 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 83.6 bits (205), Expect = 1e-16
Identities = 47/128 (36%), Positives = 70/128 (54%), Gaps = 5/128 (3%)
Query: 75 LYCRQG-YYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYL 133
LYC G ++L++ PDG +DGT+D S L + V I+ +TG Y+AM+ +G L
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLL 88
Query: 134 YPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPA 193
Y S+ EC F E + EN+Y Y S ++ + + WF+GL K G +G R + A
Sbjct: 89 YGSQTPNEECLFLERLEENHYNTYIS----KKHAEKNWFVGLKKNGSCKRGPRTHYGQKA 144
Query: 194 AHFLPKPL 201
FLP P+
Sbjct: 145 ILFLPLPV 152
>gi|153285461 fibroblast growth factor 2 [Homo sapiens]
Length = 288
Score = 74.3 bits (181), Expect = 9e-14
Identities = 44/126 (34%), Positives = 65/126 (51%), Gaps = 7/126 (5%)
Query: 74 RLYCRQG-YYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGY 132
RLYC+ G ++L++HPDG +DG ++ S L VV+I+GV Y+AM +G
Sbjct: 164 RLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGR 223
Query: 133 LYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKP 192
L S+ T EC F E + N Y Y S Y +W++ L + GQ G++ +
Sbjct: 224 LLASKCVTDECFFFERLESNNYNTYRSRKY------TSWYVALKRTGQYKLGSKTGPGQK 277
Query: 193 AAHFLP 198
A FLP
Sbjct: 278 AILFLP 283
>gi|9506597 fibroblast growth factor 21 precursor [Homo sapiens]
Length = 209
Score = 55.1 bits (131), Expect = 6e-08
Identities = 53/162 (32%), Positives = 73/162 (45%), Gaps = 26/162 (16%)
Query: 82 YLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTP 141
+L++ DG + G D S S L L + V+ I GVKT ++ +G LY S F P
Sbjct: 60 HLEIREDGTVGGAADQSPES-LLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDP 118
Query: 142 E-CKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPA----AHF 196
E C F+E + E+ Y +Y S A L L+ + GN+ PA A F
Sbjct: 119 EACSFRELLLEDGYNVYQS---------EAHGLPLH-----LPGNKSPHRDPAPRGPARF 164
Query: 197 LPKP-LEVAMYREPSL-----HDVGETVPKPGVTPSKSTSAS 232
LP P L A+ P + DVG + P V PS+ S S
Sbjct: 165 LPLPGLPPALPEPPGILAPQPPDVGSSDPLSMVGPSQGRSPS 206
>gi|10190674 fibroblast growth factor 23 precursor [Homo sapiens]
Length = 251
Score = 50.4 bits (119), Expect = 1e-06
Identities = 33/104 (31%), Positives = 50/104 (48%), Gaps = 6/104 (5%)
Query: 78 RQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSE 137
R Y+LQ+H +G +DG + S L + V I GV + Y+ M+ G ++ S
Sbjct: 48 RNSYHLQIHKNGHVDGAPHQTIYSALM-IRSEDAGFVVITGVMSRRYLCMDFRGNIFGSH 106
Query: 138 LFTPE-CKFKESVFENYYVIYSSMLYR----QQESGRAWFLGLN 176
F PE C+F+ EN Y +Y S Y + RA+ G+N
Sbjct: 107 YFDPENCRFQHQTLENGYDVYHSPQYHFLVSLGRAKRAFLPGMN 150
>gi|15147350 fibroblast growth factor 8 isoform A precursor [Homo
sapiens]
Length = 204
Score = 48.9 bits (115), Expect = 4e-06
Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 7/87 (8%)
Query: 114 VAIQGVKTGLYIAMNGEGYLY-PSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWF 172
V ++G +TGLYI MN +G L S +C F E V EN Y + Y W+
Sbjct: 86 VRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKY------EGWY 139
Query: 173 LGLNKEGQAMKGNRVKKTKPAAHFLPK 199
+ ++G+ KG++ ++ + HF+ +
Sbjct: 140 MAFTRKGRPRKGSKTRQHQREVHFMKR 166
>gi|5174439 fibroblast growth factor 8 isoform B precursor [Homo
sapiens]
Length = 215
Score = 48.9 bits (115), Expect = 4e-06
Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 7/87 (8%)
Query: 114 VAIQGVKTGLYIAMNGEGYLY-PSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWF 172
V ++G +TGLYI MN +G L S +C F E V EN Y + Y W+
Sbjct: 97 VRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKY------EGWY 150
Query: 173 LGLNKEGQAMKGNRVKKTKPAAHFLPK 199
+ ++G+ KG++ ++ + HF+ +
Sbjct: 151 MAFTRKGRPRKGSKTRQHQREVHFMKR 177
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,803,995
Number of Sequences: 37866
Number of extensions: 455083
Number of successful extensions: 1219
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 1155
Number of HSP's gapped (non-prelim): 51
length of query: 247
length of database: 18,247,518
effective HSP length: 100
effective length of query: 147
effective length of database: 14,460,918
effective search space: 2125754946
effective search space used: 2125754946
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.