Search of human proteins with 47132603

Search of human proteins with 47132603

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|47132603 deiodinase, iodothyronine, type I isoform b [Homo
sapiens]
         (185 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|47132603 deiodinase, iodothyronine, type I isoform b [Homo sa...   374   e-104
gi|4557522 deiodinase, iodothyronine, type I isoform a [Homo sap...   280   7e-76
gi|89357935 deiodinase, iodothyronine, type I isoform c [Homo sa...   266   1e-71
gi|55750011 deiodinase, iodothyronine, type III [Homo sapiens]        138   2e-33
gi|55749998 deiodinase, iodothyronine, type II isoform b [Homo s...   131   4e-31
gi|7549803 deiodinase, iodothyronine, type II isoform a [Homo sa...   131   4e-31
gi|7549805 deiodinase, iodothyronine, type II isoform a [Homo sa...   131   4e-31
gi|89357938 deiodinase, iodothyronine, type I isoform d [Homo sa...   101   3e-22
gi|5803011 enolase 2 [Homo sapiens]                                    31   0.53 
gi|74319833 ubiquitin specific protease 9, Y-linked [Homo sapiens]     28   5.9  
gi|145309311 ubiquitin specific protease 9, X-linked isoform 4 [...    28   5.9  
gi|145309309 ubiquitin specific protease 9, X-linked isoform 3 [...    28   5.9  
gi|89111953 transmembrane protein 132B [Homo sapiens]                  27   7.7  

>gi|47132603 deiodinase, iodothyronine, type I isoform b [Homo
           sapiens]
          Length = 185

 Score =  374 bits (961), Expect = e-104
 Identities = 185/185 (100%), Positives = 185/185 (100%)

Query: 1   MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGNRPLVLNFGSC 60
           MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGNRPLVLNFGSC
Sbjct: 1   MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGNRPLVLNFGSC 60

Query: 61  TUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASDGWAFKNNMDIRNHQNLQDRLQAA 120
           T PSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASDGWAFKNNMDIRNHQNLQDRLQAA
Sbjct: 61  TUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASDGWAFKNNMDIRNHQNLQDRLQAA 120

Query: 121 HLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKGKSGPWNYNPEEVRAVL 180
           HLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKGKSGPWNYNPEEVRAVL
Sbjct: 121 HLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKGKSGPWNYNPEEVRAVL 180

Query: 181 EKLHS 185
           EKLHS
Sbjct: 181 EKLHS 185


>gi|4557522 deiodinase, iodothyronine, type I isoform a [Homo
           sapiens]
          Length = 249

 Score =  280 bits (715), Expect = 7e-76
 Identities = 137/137 (100%), Positives = 137/137 (100%)

Query: 49  GNRPLVLNFGSCTUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASDGWAFKNNMDIR 108
           GNRPLVLNFGSCT PSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASDGWAFKNNMDIR
Sbjct: 113 GNRPLVLNFGSCTUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASDGWAFKNNMDIR 172

Query: 109 NHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKGKSGP 168
           NHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKGKSGP
Sbjct: 173 NHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKGKSGP 232

Query: 169 WNYNPEEVRAVLEKLHS 185
           WNYNPEEVRAVLEKLHS
Sbjct: 233 WNYNPEEVRAVLEKLHS 249



 Score =  101 bits (252), Expect = 3e-22
 Identities = 49/49 (100%), Positives = 49/49 (100%)

Query: 1  MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTG 49
          MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTG
Sbjct: 1  MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTG 49


>gi|89357935 deiodinase, iodothyronine, type I isoform c [Homo
           sapiens]
          Length = 201

 Score =  266 bits (679), Expect = 1e-71
 Identities = 147/203 (72%), Positives = 158/203 (77%), Gaps = 20/203 (9%)

Query: 1   MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTG--------NRP 52
           MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTG        +  
Sbjct: 1   MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDN 60

Query: 53  LVLNFGSCTUPSFMFKFDQFKRLIEDFSSIADFL----VIYIEEAHAS------DGWAFK 102
            +  F S     F+ K  +++RL ED + +        V+ +     +      DGWAFK
Sbjct: 61  WIPTFFSTQYFWFVLKV-RWQRL-EDTTELGGLAPNCPVVRLSGQRCNIWEFMQDGWAFK 118

Query: 103 NNMDIRNHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILY 162
           NNMDIRNHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILY
Sbjct: 119 NNMDIRNHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILY 178

Query: 163 KGKSGPWNYNPEEVRAVLEKLHS 185
           KGKSGPWNYNPEEVRAVLEKLHS
Sbjct: 179 KGKSGPWNYNPEEVRAVLEKLHS 201


>gi|55750011 deiodinase, iodothyronine, type III [Homo sapiens]
          Length = 278

 Score =  138 bits (348), Expect = 2e-33
 Identities = 70/135 (51%), Positives = 90/135 (66%), Gaps = 1/135 (0%)

Query: 49  GNRPLVLNFGSCTUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASDGWAFKNN-MDI 107
           GNRPLVLNFGSCT P FM +   F+RL+  +    DFL+IYIEEAH SDGW   ++   I
Sbjct: 131 GNRPLVLNFGSCTUPPFMARMSAFQRLVTKYQRDVDFLIIYIEEAHPSDGWVTTDSPYII 190

Query: 108 RNHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKGKSG 167
             H++L+DR+ AA +L   +P C +V+DTM N SS  Y A  ERLY+IQ G I+Y+G  G
Sbjct: 191 PQHRSLEDRVSAARVLQQGAPGCALVLDTMANSSSSAYGAYFERLYVIQSGTIMYQGGRG 250

Query: 168 PWNYNPEEVRAVLEK 182
           P  Y   E+R  LE+
Sbjct: 251 PDGYQVSELRTWLER 265


>gi|55749998 deiodinase, iodothyronine, type II isoform b [Homo
           sapiens]
          Length = 309

 Score =  131 bits (329), Expect = 4e-31
 Identities = 68/139 (48%), Positives = 91/139 (65%), Gaps = 7/139 (5%)

Query: 51  RPLVLNFGSCTUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASDGWAFKN----NMD 106
           RPLV+NFGS T P F  +   F++L+E+FSS+ADFL++YI+EAH SDGWA       + +
Sbjct: 158 RPLVVNFGSATUPPFTSQLPAFRKLVEEFSSVADFLLVYIDEAHPSDGWAIPGDSSLSFE 217

Query: 107 IRNHQNLQDRLQAAHLLLAR---SPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYK 163
           ++ HQN +DR  AA  LL R    PQC VV D M N ++  Y    ER+ I+Q  +I Y 
Sbjct: 218 VKKHQNQEDRCAAAQQLLERFSLPPQCRVVADRMDNNANIAYGVAFERVCIVQRQKIAYL 277

Query: 164 GKSGPWNYNPEEVRAVLEK 182
           G  GP++YN +EVR  LEK
Sbjct: 278 GGKGPFSYNLQEVRHWLEK 296


>gi|7549803 deiodinase, iodothyronine, type II isoform a [Homo
           sapiens]
          Length = 273

 Score =  131 bits (329), Expect = 4e-31
 Identities = 68/139 (48%), Positives = 91/139 (65%), Gaps = 7/139 (5%)

Query: 51  RPLVLNFGSCTUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASDGWAFKN----NMD 106
           RPLV+NFGS T P F  +   F++L+E+FSS+ADFL++YI+EAH SDGWA       + +
Sbjct: 122 RPLVVNFGSATUPPFTSQLPAFRKLVEEFSSVADFLLVYIDEAHPSDGWAIPGDSSLSFE 181

Query: 107 IRNHQNLQDRLQAAHLLLAR---SPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYK 163
           ++ HQN +DR  AA  LL R    PQC VV D M N ++  Y    ER+ I+Q  +I Y 
Sbjct: 182 VKKHQNQEDRCAAAQQLLERFSLPPQCRVVADRMDNNANIAYGVAFERVCIVQRQKIAYL 241

Query: 164 GKSGPWNYNPEEVRAVLEK 182
           G  GP++YN +EVR  LEK
Sbjct: 242 GGKGPFSYNLQEVRHWLEK 260


>gi|7549805 deiodinase, iodothyronine, type II isoform a [Homo
           sapiens]
          Length = 273

 Score =  131 bits (329), Expect = 4e-31
 Identities = 68/139 (48%), Positives = 91/139 (65%), Gaps = 7/139 (5%)

Query: 51  RPLVLNFGSCTUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASDGWAFKN----NMD 106
           RPLV+NFGS T P F  +   F++L+E+FSS+ADFL++YI+EAH SDGWA       + +
Sbjct: 122 RPLVVNFGSATUPPFTSQLPAFRKLVEEFSSVADFLLVYIDEAHPSDGWAIPGDSSLSFE 181

Query: 107 IRNHQNLQDRLQAAHLLLAR---SPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYK 163
           ++ HQN +DR  AA  LL R    PQC VV D M N ++  Y    ER+ I+Q  +I Y 
Sbjct: 182 VKKHQNQEDRCAAAQQLLERFSLPPQCRVVADRMDNNANIAYGVAFERVCIVQRQKIAYL 241

Query: 164 GKSGPWNYNPEEVRAVLEK 182
           G  GP++YN +EVR  LEK
Sbjct: 242 GGKGPFSYNLQEVRHWLEK 260


>gi|89357938 deiodinase, iodothyronine, type I isoform d [Homo
          sapiens]
          Length = 161

 Score =  101 bits (252), Expect = 3e-22
 Identities = 49/49 (100%), Positives = 49/49 (100%)

Query: 1  MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTG 49
          MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTG
Sbjct: 1  MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTG 49



 Score = 98.2 bits (243), Expect = 4e-21
 Identities = 48/48 (100%), Positives = 48/48 (100%)

Query: 49  GNRPLVLNFGSCTUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHAS 96
           GNRPLVLNFGSCT PSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHAS
Sbjct: 113 GNRPLVLNFGSCTUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHAS 160


>gi|5803011 enolase 2 [Homo sapiens]
          Length = 434

 Score = 31.2 bits (69), Expect = 0.53
 Identities = 18/46 (39%), Positives = 24/46 (52%), Gaps = 2/46 (4%)

Query: 55  LNFGSCTUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASDGWA 100
           L+F S T PS     DQ   L +DF  + D+ V+ IE+    D WA
Sbjct: 259 LDFKSPTDPSRYITGDQLGALYQDF--VRDYPVVSIEDPFDQDDWA 302


>gi|74319833 ubiquitin specific protease 9, Y-linked [Homo sapiens]
          Length = 2555

 Score = 27.7 bits (60), Expect = 5.9
 Identities = 11/15 (73%), Positives = 13/15 (86%)

Query: 104  NMDIRNHQNLQDRLQ 118
            N+DIRNHQNL D L+
Sbjct: 1743 NVDIRNHQNLLDSLE 1757


>gi|145309311 ubiquitin specific protease 9, X-linked isoform 4 [Homo
            sapiens]
          Length = 2554

 Score = 27.7 bits (60), Expect = 5.9
 Identities = 11/15 (73%), Positives = 13/15 (86%)

Query: 104  NMDIRNHQNLQDRLQ 118
            N+DIRNHQNL D L+
Sbjct: 1741 NVDIRNHQNLLDSLE 1755


>gi|145309309 ubiquitin specific protease 9, X-linked isoform 3 [Homo
            sapiens]
          Length = 2570

 Score = 27.7 bits (60), Expect = 5.9
 Identities = 11/15 (73%), Positives = 13/15 (86%)

Query: 104  NMDIRNHQNLQDRLQ 118
            N+DIRNHQNL D L+
Sbjct: 1741 NVDIRNHQNLLDSLE 1755


>gi|89111953 transmembrane protein 132B [Homo sapiens]
          Length = 1078

 Score = 27.3 bits (59), Expect = 7.7
 Identities = 14/54 (25%), Positives = 30/54 (55%), Gaps = 1/54 (1%)

Query: 76  IEDFSSIADFLVIYIEEAHASDGWAFKN-NMDIRNHQNLQDRLQAAHLLLARSP 128
           ++ FSS+  +L   +  ++A + +  K  N D+  + +LQ R++   +  AR+P
Sbjct: 28  LQKFSSLPAYLPTNLHISNAEESFFLKEANQDLTRNSSLQARVEPFFIYRARTP 81


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.139    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,932,950
Number of Sequences: 37866
Number of extensions: 265278
Number of successful extensions: 504
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 483
Number of HSP's gapped (non-prelim): 16
length of query: 185
length of database: 18,247,518
effective HSP length: 96
effective length of query: 89
effective length of database: 14,612,382
effective search space: 1300501998
effective search space used: 1300501998
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.