Search of human proteins with 4557873

Search of human proteins with 4557873

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557873 uroporphyrinogen III synthase [Homo sapiens]
         (265 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557873 uroporphyrinogen III synthase [Homo sapiens]               532   e-151
gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens]               31   1.3  
gi|10880985 interferon, alpha 17 [Homo sapiens]                        29   3.7  
gi|18702325 cAMP responsive element binding protein 3-like 4 [Ho...    29   3.7  
gi|16306552 semaphorin Y [Homo sapiens]                                29   4.8  
gi|38261971 cyclic AMP-regulated phosphoprotein, 21 kD isoform 1...    28   6.3  
gi|17978466 cyclin T1 [Homo sapiens]                                   28   8.3  
gi|27886561 nuclear factor of activated T-cells, cytoplasmic, ca...    28   8.3  
gi|115527120 nebulin [Homo sapiens]                                    28   8.3  
gi|158534077 regulator of G-protein signaling 22 [Homo sapiens]        28   8.3  

>gi|4557873 uroporphyrinogen III synthase [Homo sapiens]
          Length = 265

 Score =  532 bits (1370), Expect = e-151
 Identities = 265/265 (100%), Positives = 265/265 (100%)

Query: 1   MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI 60
           MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI
Sbjct: 1   MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLI 60

Query: 61  FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG 120
           FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG
Sbjct: 61  FTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCG 120

Query: 121 NAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNL 180
           NAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNL
Sbjct: 121 NAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNL 180

Query: 181 NSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKFAAIGPTTARALAAQGLPVS 240
           NSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKFAAIGPTTARALAAQGLPVS
Sbjct: 181 NSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKFAAIGPTTARALAAQGLPVS 240

Query: 241 CTAESPTPQALATGIRKALQPHGCC 265
           CTAESPTPQALATGIRKALQPHGCC
Sbjct: 241 CTAESPTPQALATGIRKALQPHGCC 265


>gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens]
          Length = 332

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 15/37 (40%), Positives = 23/37 (62%)

Query: 217 DQIKFAAIGPTTARALAAQGLPVSCTAESPTPQALAT 253
           ++++  AIGP+  R+LA  G P   +AESP+  A  T
Sbjct: 268 NRLQHQAIGPSGMRSLAEPGCPTHGSAESPSTAASPT 304


>gi|10880985 interferon, alpha 17 [Homo sapiens]
          Length = 189

 Score = 29.3 bits (64), Expect = 3.7
 Identities = 14/67 (20%), Positives = 33/67 (49%), Gaps = 7/67 (10%)

Query: 54  EDYGGLIFTSPRAVEAAELCLEQN-------NKTEVWERSLKEKWNAKSVYVVGNATASL 106
           E++ G  F   +A+      ++Q        + +  WE+SL EK++ +    + N  A +
Sbjct: 64  EEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLEACV 123

Query: 107 VSKIGLD 113
           + ++G++
Sbjct: 124 IQEVGME 130


>gi|18702325 cAMP responsive element binding protein 3-like 4 [Homo
           sapiens]
          Length = 395

 Score = 29.3 bits (64), Expect = 3.7
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 9/84 (10%)

Query: 32  LIPVLSFEFLSLPSFSEKLSHPEDYGGLIFTSPRAVEAAELC----LEQNNKTEVWERSL 87
           LI + S   + LPSFS   S PE   G     P  V +  +     + +N +T+V E  L
Sbjct: 299 LILLFSLALIILPSFSPFQSRPE--AGSEDYQPHGVTSRNILTHKDVTENLETQVVESRL 356

Query: 88  KEKWNAKSVYVVGNATASLVSKIG 111
           +E   AK       +T +L+ K+G
Sbjct: 357 REPPGAKD---ANGSTRTLLEKMG 377


>gi|16306552 semaphorin Y [Homo sapiens]
          Length = 930

 Score = 28.9 bits (63), Expect = 4.8
 Identities = 14/40 (35%), Positives = 19/40 (47%)

Query: 226 PTTARALAAQGLPVSCTAESPTPQALATGIRKALQPHGCC 265
           P T+RAL  +  P      SP P   A+ +R  + P G C
Sbjct: 789 PLTSRALPPEPAPALLGGPSPRPHECASPLRLDVPPEGRC 828


>gi|38261971 cyclic AMP-regulated phosphoprotein, 21 kD isoform 1
           [Homo sapiens]
          Length = 812

 Score = 28.5 bits (62), Expect = 6.3
 Identities = 22/72 (30%), Positives = 30/72 (41%), Gaps = 3/72 (4%)

Query: 181 NSYYSQQGVPASITFFS-PSGLTYSLKHIQELSGDNIDQIKFAAIGPTTAR--ALAAQGL 237
           N   +QQG P      S P+  +Y +   Q   G      +   + P  A   +L A G+
Sbjct: 703 NVINNQQGTPVQSVMVSYPTMSSYQVPMTQGSQGLPQQSYQQPIMLPNQAGQGSLPATGM 762

Query: 238 PVSCTAESPTPQ 249
           PV C    PTPQ
Sbjct: 763 PVYCNVTPPTPQ 774


>gi|17978466 cyclin T1 [Homo sapiens]
          Length = 726

 Score = 28.1 bits (61), Expect = 8.3
 Identities = 12/29 (41%), Positives = 16/29 (55%)

Query: 36  LSFEFLSLPSFSEKLSHPEDYGGLIFTSP 64
           L+F F SLP+  +   H  D  GL F+ P
Sbjct: 600 LNFSFPSLPTMGQMPGHSSDTSGLSFSQP 628


>gi|27886561 nuclear factor of activated T-cells, cytoplasmic,
            calcineurin-dependent 3 isoform 1 [Homo sapiens]
          Length = 1075

 Score = 28.1 bits (61), Expect = 8.3
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 20/78 (25%)

Query: 190  PASITFFSPSGLTYSLKH-------------IQELSGDNIDQIKFAAIGPTTARALAAQG 236
            PAS   F P G T S+K              +Q+++ D++++I    IG   ++   +QG
Sbjct: 1000 PAS---FPPDGATVSIKPEPEDREPNFATIGLQDITLDDVNEI----IGRDMSQISVSQG 1052

Query: 237  LPVSCTAESPTPQALATG 254
              VS  A  P+P++L  G
Sbjct: 1053 AGVSRQAPLPSPESLDLG 1070


>gi|115527120 nebulin [Homo sapiens]
          Length = 6669

 Score = 28.1 bits (61), Expect = 8.3
 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 13/86 (15%)

Query: 33   IPVLSFEFLSLPSFSEKLS------HPEDYGGLIFTSPRAVEAAELCLEQNNKTEVWERS 86
            +P+ S E        E LS      HPE    L FT   A++  E  L ++NK  + +R 
Sbjct: 1694 VPIESLEVEKAKKAGEILSEKKYRQHPEK---LKFTY--AMDTMEQALNKSNKLNMDKRL 1748

Query: 87   LKEKWN--AKSVYVVGNATASLVSKI 110
              EKWN    +++V+ +    L+S++
Sbjct: 1749 YTEKWNKDKTTIHVMPDTPDILLSRV 1774


>gi|158534077 regulator of G-protein signaling 22 [Homo sapiens]
          Length = 1264

 Score = 28.1 bits (61), Expect = 8.3
 Identities = 12/19 (63%), Positives = 14/19 (73%)

Query: 39 EFLSLPSFSEKLSHPEDYG 57
          EFLSLP+FSE +    DYG
Sbjct: 34 EFLSLPTFSEAIRFNADYG 52


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.133    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,405,192
Number of Sequences: 37866
Number of extensions: 454844
Number of successful extensions: 1177
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1171
Number of HSP's gapped (non-prelim): 11
length of query: 265
length of database: 18,247,518
effective HSP length: 100
effective length of query: 165
effective length of database: 14,460,918
effective search space: 2386051470
effective search space used: 2386051470
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.