Guide to the Human Genome
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Search of human proteins with 4557839

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557839 phosphomannomutase 2 [Homo sapiens]
         (246 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557839 phosphomannomutase 2 [Homo sapiens]                        506   e-144
gi|194097356 phosphomannomutase 1 [Homo sapiens]                      343   1e-94
gi|7662180 glycine-, glutamate-, thienylcyclohexylpiperidine-bin...    30   2.5  
gi|7656971 phosphonoformate immuno-associated protein 5 isoform ...    29   4.3  
gi|154091028 sorting nexin 29 [Homo sapiens]                           28   5.6  
gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]        28   9.5  
gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]        28   9.5  
gi|26190608 synaptojanin 2 [Homo sapiens]                              28   9.5  

>gi|4557839 phosphomannomutase 2 [Homo sapiens]
          Length = 246

 Score =  506 bits (1304), Expect = e-144
 Identities = 246/246 (100%), Positives = 246/246 (100%)

Query: 1   MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDV 60
           MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDV
Sbjct: 1   MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDV 60

Query: 61  VEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFI 120
           VEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFI
Sbjct: 61  VEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFI 120

Query: 121 EFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISF 180
           EFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISF
Sbjct: 121 EFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISF 180

Query: 181 DVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRI 240
           DVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRI
Sbjct: 181 DVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRI 240

Query: 241 CELLFS 246
           CELLFS
Sbjct: 241 CELLFS 246


>gi|194097356 phosphomannomutase 1 [Homo sapiens]
          Length = 262

 Score =  343 bits (879), Expect = 1e-94
 Identities = 164/240 (68%), Positives = 199/240 (82%), Gaps = 2/240 (0%)

Query: 8   LCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGN--DVVEKYD 65
           LCLFDVDGTLT  RQKI  E+  FLQKLR +++IGVVGGSD+ K+ EQLG+  +V+EK+D
Sbjct: 15  LCLFDVDGTLTPARQKIDPEVAAFLQKLRSRVQIGVVGGSDYCKIAEQLGDGDEVIEKFD 74

Query: 66  YVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNG 125
           YVF ENG V YK G+LL +Q IQ+HLGE L+QDLIN+CLSY+A ++LPKKRGTFIEFRNG
Sbjct: 75  YVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCLSYMALLRLPKKRGTFIEFRNG 134

Query: 126 MLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPD 185
           MLN+SPIGRSC+ EERIEF ELDKKE IR+KFV  L+ EFAGKGL FS GG ISFDVFP+
Sbjct: 135 MLNISPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKGLRFSRGGMISFDVFPE 194

Query: 186 GWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLF 245
           GWDKRYCL  ++ D + TI+FFG++T PGGND EIF DPRT+G+SV +P+DT + C  +F
Sbjct: 195 GWDKRYCLDSLDQDSFDTIHFFGNETSPGGNDFEIFADPRTVGHSVVSPQDTVQRCREIF 254


>gi|7662180 glycine-, glutamate-,
           thienylcyclohexylpiperidine-binding protein [Homo
           sapiens]
          Length = 925

 Score = 29.6 bits (65), Expect = 2.5
 Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 7/43 (16%)

Query: 21  RQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEK 63
           R+ + KE  D+ +KL+Q I       +D +KV E+LG   VEK
Sbjct: 222 REAVQKERYDYAKKLKQAI-------ADLQKVGERLGRYEVEK 257


>gi|7656971 phosphonoformate immuno-associated protein 5 isoform 2
          [Homo sapiens]
          Length = 583

 Score = 28.9 bits (63), Expect = 4.3
 Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 5/53 (9%)

Query: 12 DVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVV---GGSDFEKVQEQLGNDVV 61
          +++G    PR+++T E     +KL+   +  V      +DF ++QE+ GND V
Sbjct: 5  EIEGKFLGPREEVTSEPR--CKKLKSTTESYVFHNHSNADFHRIQEKTGNDWV 55


>gi|154091028 sorting nexin 29 [Homo sapiens]
          Length = 428

 Score = 28.5 bits (62), Expect = 5.6
 Identities = 18/89 (20%), Positives = 41/89 (46%), Gaps = 7/89 (7%)

Query: 47  SDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLL--CRQNIQSHLGEALIQDLINYCL 104
           ++F  +  +L N   +   Y FP    +  KD K +   R+ +Q++L     + ++N  +
Sbjct: 311 TEFRSLHHKLQNKYPQVRAYNFPPKKAIGNKDAKFVEERRKQLQNYL-----RSVMNKVI 365

Query: 105 SYIAKIKLPKKRGTFIEFRNGMLNVSPIG 133
             + +     K+ T I+     ++++P G
Sbjct: 366 QMVPEFAASPKKETLIQLMPFFVDITPPG 394


>gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]
          Length = 1712

 Score = 27.7 bits (60), Expect = 9.5
 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 5/67 (7%)

Query: 128 NVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAG--KGLTFSIGGQISFDVFPD 185
           NV+  G+      R+EF+ ++      ++F++ +   F G   GL F+  GQ   D   D
Sbjct: 841 NVTVEGQMAGAHMRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFN--GQPYMDQCKD 898

Query: 186 GWDKRYC 192
           G D  YC
Sbjct: 899 G-DITYC 904


>gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]
          Length = 1642

 Score = 27.7 bits (60), Expect = 9.5
 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 5/67 (7%)

Query: 128 NVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAG--KGLTFSIGGQISFDVFPD 185
           NV+  G+      R+EF+ ++      ++F++ +   F G   GL F+  GQ   D   D
Sbjct: 801 NVTVEGQMAGAHMRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFN--GQPYMDQCKD 858

Query: 186 GWDKRYC 192
           G D  YC
Sbjct: 859 G-DITYC 864


>gi|26190608 synaptojanin 2 [Homo sapiens]
          Length = 1496

 Score = 27.7 bits (60), Expect = 9.5
 Identities = 14/33 (42%), Positives = 16/33 (48%)

Query: 116  RGTFIEFRNGMLNVSPIGRSCSQEERIEFYELD 148
            R   I  R+ M  VSP   SC  EE  +F  LD
Sbjct: 975  REEIIRKRDSMAPVSPTANSCLLEENFDFTSLD 1007


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.142    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,165,629
Number of Sequences: 37866
Number of extensions: 450145
Number of successful extensions: 812
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 808
Number of HSP's gapped (non-prelim): 8
length of query: 246
length of database: 18,247,518
effective HSP length: 100
effective length of query: 146
effective length of database: 14,460,918
effective search space: 2111294028
effective search space used: 2111294028
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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