Search of human proteins with 4557781

Search of human proteins with 4557781

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557781 alpha-N-acetylgalactosaminidase precursor [Homo
sapiens]
         (411 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557781 alpha-N-acetylgalactosaminidase precursor [Homo sapiens]   860   0.0  
gi|4504009 alpha-galactosidase A precursor [Homo sapiens]             367   e-101
gi|239755027 PREDICTED: hypothetical protein [Homo sapiens]            32   1.0  
gi|239749540 PREDICTED: hypothetical protein [Homo sapiens]            32   1.0  
gi|239743690 PREDICTED: hypothetical protein XP_002342947 [Homo ...    32   1.0  
gi|156105693 PPAR-alpha interacting complex protein 285 isoform ...    30   4.0  
gi|156105695 PPAR-alpha interacting complex protein 285 isoform ...    30   4.0  
gi|126091152 cubilin [Homo sapiens]                                    29   8.9  

>gi|4557781 alpha-N-acetylgalactosaminidase precursor [Homo sapiens]
          Length = 411

 Score =  860 bits (2222), Expect = 0.0
 Identities = 411/411 (100%), Positives = 411/411 (100%)

Query: 1   MLLKTVLLLGHVAQVLMLDNGLLQTPPMGWLAWERFRCNINCDEDPKNCISEQLFMEMAD 60
           MLLKTVLLLGHVAQVLMLDNGLLQTPPMGWLAWERFRCNINCDEDPKNCISEQLFMEMAD
Sbjct: 1   MLLKTVLLLGHVAQVLMLDNGLLQTPPMGWLAWERFRCNINCDEDPKNCISEQLFMEMAD 60

Query: 61  RMAQDGWRDMGYTYLNIDDCWIGGRDASGRLMPDPKRFPHGIPFLADYVHSLGLKLGIYA 120
           RMAQDGWRDMGYTYLNIDDCWIGGRDASGRLMPDPKRFPHGIPFLADYVHSLGLKLGIYA
Sbjct: 61  RMAQDGWRDMGYTYLNIDDCWIGGRDASGRLMPDPKRFPHGIPFLADYVHSLGLKLGIYA 120

Query: 121 DMGNFTCMGYPGTTLDKVVQDAQTFAEWKVDMLKLDGCFSTPEERAQGYPKMAAALNATG 180
           DMGNFTCMGYPGTTLDKVVQDAQTFAEWKVDMLKLDGCFSTPEERAQGYPKMAAALNATG
Sbjct: 121 DMGNFTCMGYPGTTLDKVVQDAQTFAEWKVDMLKLDGCFSTPEERAQGYPKMAAALNATG 180

Query: 181 RPIAFSCSWPAYEGGLPPRVNYSLLADICNLWRNYDDIQDSWWSVLSILNWFVEHQDILQ 240
           RPIAFSCSWPAYEGGLPPRVNYSLLADICNLWRNYDDIQDSWWSVLSILNWFVEHQDILQ
Sbjct: 181 RPIAFSCSWPAYEGGLPPRVNYSLLADICNLWRNYDDIQDSWWSVLSILNWFVEHQDILQ 240

Query: 241 PVAGPGHWNDPDMLLIGNFGLSLEQSRAQMALWTVLAAPLLMSTDLRTISAQNMDILQNP 300
           PVAGPGHWNDPDMLLIGNFGLSLEQSRAQMALWTVLAAPLLMSTDLRTISAQNMDILQNP
Sbjct: 241 PVAGPGHWNDPDMLLIGNFGLSLEQSRAQMALWTVLAAPLLMSTDLRTISAQNMDILQNP 300

Query: 301 LMIKINQDPLGIQGRRIHKEKSLIEVYMRPLSNKASALVFFSCRTDMPYRYHSSLGQLNF 360
           LMIKINQDPLGIQGRRIHKEKSLIEVYMRPLSNKASALVFFSCRTDMPYRYHSSLGQLNF
Sbjct: 301 LMIKINQDPLGIQGRRIHKEKSLIEVYMRPLSNKASALVFFSCRTDMPYRYHSSLGQLNF 360

Query: 361 TGSVIYEAQDVYSGDIISGLRDETNFTVIINPSGVVMWYLYPIKNLEMSQQ 411
           TGSVIYEAQDVYSGDIISGLRDETNFTVIINPSGVVMWYLYPIKNLEMSQQ
Sbjct: 361 TGSVIYEAQDVYSGDIISGLRDETNFTVIINPSGVVMWYLYPIKNLEMSQQ 411


>gi|4504009 alpha-galactosidase A precursor [Homo sapiens]
          Length = 429

 Score =  367 bits (941), Expect = e-101
 Identities = 184/327 (56%), Positives = 228/327 (69%), Gaps = 5/327 (1%)

Query: 18  LDNGLLQTPPMGWLAWERFRCNINCDEDPKNCISEQLFMEMADRMAQDGWRDMGYTYLNI 77
           LDNGL +TP MGWL WERF CN++C E+P +CISE+LFMEMA+ M  +GW+D GY YL I
Sbjct: 32  LDNGLARTPTMGWLHWERFMCNLDCQEEPDSCISEKLFMEMAELMVSEGWKDAGYEYLCI 91

Query: 78  DDCWIGG-RDASGRLMPDPKRFPHGIPFLADYVHSLGLKLGIYADMGNFTCMGYPGTTLD 136
           DDCW+   RD+ GRL  DP+RFPHGI  LA+YVHS GLKLGIYAD+GN TC G+PG+   
Sbjct: 92  DDCWMAPQRDSEGRLQADPQRFPHGIRQLANYVHSKGLKLGIYADVGNKTCAGFPGS-FG 150

Query: 137 KVVQDAQTFAEWKVDMLKLDGCF-STPEERAQGYPKMAAALNATGRPIAFSCSWPAYEGG 195
               DAQTFA+W VD+LK DGC+  + E  A GY  M+ ALN TGR I +SC WP Y   
Sbjct: 151 YYDIDAQTFADWGVDLLKFDGCYCDSLENLADGYKHMSLALNRTGRSIVYSCEWPLYMWP 210

Query: 196 LPPRVNYSLLADICNLWRNYDDIQDSWWSVLSILNWFVEHQDILQPVAGPGHWNDPDMLL 255
              + NY+ +   CN WRN+ DI DSW S+ SIL+W   +Q+ +  VAGPG WNDPDML+
Sbjct: 211 FQ-KPNYTEIRQYCNHWRNFADIDDSWKSIKSILDWTSFNQERIVDVAGPGGWNDPDMLV 269

Query: 256 IGNFGLSLEQSRAQMALWTVLAAPLLMSTDLRTISAQNMDILQNPLMIKINQDPLGIQGR 315
           IGNFGLS  Q   QMALW ++AAPL MS DLR IS Q   +LQ+  +I INQDPLG QG 
Sbjct: 270 IGNFGLSWNQQVTQMALWAIMAAPLFMSNDLRHISPQAKALLQDKDVIAINQDPLGKQGY 329

Query: 316 RIHKEKSLIEVYMRPLSNKASALVFFS 342
           ++ ++    EV+ RPLS  A A+   +
Sbjct: 330 QL-RQGDNFEVWERPLSGLAWAVAMIN 355


>gi|239755027 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 239

 Score = 32.0 bits (71), Expect = 1.0
 Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 5/73 (6%)

Query: 251 PDMLLIGNFGLSLEQSRAQMALWTVLAAPLLMSTDLR---TISAQNMDILQNPLMIKINQ 307
           PD   +G  GLS   SR+     + L AP L S DL    + +AQ      +PL     +
Sbjct: 4   PDAQDLGTAGLSFGASRSPRETSSRLIAPTLCSFDLSKKISFAAQEAAPPWSPLRHLPQR 63

Query: 308 DPL--GIQGRRIH 318
           DPL  G++G R H
Sbjct: 64  DPLIPGLEGSRSH 76


>gi|239749540 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 239

 Score = 32.0 bits (71), Expect = 1.0
 Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 5/73 (6%)

Query: 251 PDMLLIGNFGLSLEQSRAQMALWTVLAAPLLMSTDLR---TISAQNMDILQNPLMIKINQ 307
           PD   +G  GLS   SR+     + L AP L S DL    + +AQ      +PL     +
Sbjct: 4   PDAQDLGTAGLSFGASRSPRETSSRLIAPTLCSFDLSKKISFAAQEAAPPWSPLRHLPQR 63

Query: 308 DPL--GIQGRRIH 318
           DPL  G++G R H
Sbjct: 64  DPLIPGLEGSRSH 76


>gi|239743690 PREDICTED: hypothetical protein XP_002342947 [Homo
           sapiens]
          Length = 239

 Score = 32.0 bits (71), Expect = 1.0
 Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 5/73 (6%)

Query: 251 PDMLLIGNFGLSLEQSRAQMALWTVLAAPLLMSTDLR---TISAQNMDILQNPLMIKINQ 307
           PD   +G  GLS   SR+     + L AP L S DL    + +AQ      +PL     +
Sbjct: 4   PDAQDLGTAGLSFGASRSPRETSSRLIAPTLCSFDLSKKISFAAQEAAPPWSPLRHLPQR 63

Query: 308 DPL--GIQGRRIH 318
           DPL  G++G R H
Sbjct: 64  DPLIPGLEGSRSH 76


>gi|156105693 PPAR-alpha interacting complex protein 285 isoform 1
            [Homo sapiens]
          Length = 2649

 Score = 30.0 bits (66), Expect = 4.0
 Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 18/97 (18%)

Query: 92   MPDPKRFPHGIPFLADYVHSL----GLKL----GIYADMGNFTCMGYPGTTLDKVVQDAQ 143
            +PDP   P+G   LA++ H+L    GL+L     +Y+  G+   +  PGT  D      +
Sbjct: 1765 LPDPCPVPYGSLQLAEHPHALAGRPGLRLLWRRRVYSAQGSSPPLPLPGTVPDPHTLAVE 1824

Query: 144  TFAEWKVDMLKLDGCFSTPEERAQGYPKMAAALNATG 180
            T A WK  +L+L           Q +P+ AA +   G
Sbjct: 1825 T-ALWK-QLLEL--------VELQRWPEAAALIQEKG 1851


>gi|156105695 PPAR-alpha interacting complex protein 285 isoform 2
            [Homo sapiens]
          Length = 2080

 Score = 30.0 bits (66), Expect = 4.0
 Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 18/97 (18%)

Query: 92   MPDPKRFPHGIPFLADYVHSL----GLKL----GIYADMGNFTCMGYPGTTLDKVVQDAQ 143
            +PDP   P+G   LA++ H+L    GL+L     +Y+  G+   +  PGT  D      +
Sbjct: 1196 LPDPCPVPYGSLQLAEHPHALAGRPGLRLLWRRRVYSAQGSSPPLPLPGTVPDPHTLAVE 1255

Query: 144  TFAEWKVDMLKLDGCFSTPEERAQGYPKMAAALNATG 180
            T A WK  +L+L           Q +P+ AA +   G
Sbjct: 1256 T-ALWK-QLLEL--------VELQRWPEAAALIQEKG 1282


>gi|126091152 cubilin [Homo sapiens]
          Length = 3623

 Score = 28.9 bits (63), Expect = 8.9
 Identities = 13/31 (41%), Positives = 16/31 (51%), Gaps = 6/31 (19%)

Query: 118  IYADMGNFTCMGYPGTTLDKVVQDAQTFAEW 148
            +Y D G+FT  GYPGT          T+ EW
Sbjct: 3515 LYGDRGSFTSPGYPGT------YPNNTYCEW 3539


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.139    0.448 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,705,672
Number of Sequences: 37866
Number of extensions: 756213
Number of successful extensions: 1198
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1191
Number of HSP's gapped (non-prelim): 9
length of query: 411
length of database: 18,247,518
effective HSP length: 105
effective length of query: 306
effective length of database: 14,271,588
effective search space: 4367105928
effective search space used: 4367105928
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.