Guide to the Human Genome
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Search of human proteins with 4557263

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557263 ADP-ribosylarginine hydrolase [Homo sapiens]
         (357 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557263 ADP-ribosylarginine hydrolase [Homo sapiens]               744   0.0  
gi|21702735 ADP-ribosylhydrolase like 1 isoform 1 [Homo sapiens]      309   2e-84
gi|40316946 ADP-ribosylhydrolase like 1 isoform 2 [Homo sapiens]      250   1e-66
gi|8923417 ADP-ribosylhydrolase like 2 [Homo sapiens]                  32   0.87 
gi|239743879 PREDICTED: hypothetical protein XP_002342985 [Homo ...    30   2.5  
gi|7706671 peroxisomal biogenesis factor 5-like [Homo sapiens]         30   2.5  
gi|42476130 ubiquitin interaction motif containing 1 [Homo sapiens]    29   7.4  
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]                    28   9.7  
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                    28   9.7  
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]                    28   9.7  
gi|197313787 desmoglein 4 isoform 1 [Homo sapiens]                     28   9.7  
gi|29789445 desmoglein 4 isoform 2 [Homo sapiens]                      28   9.7  

>gi|4557263 ADP-ribosylarginine hydrolase [Homo sapiens]
          Length = 357

 Score =  744 bits (1920), Expect = 0.0
 Identities = 357/357 (100%), Positives = 357/357 (100%)

Query: 1   MEKYVAAMVLSAAGDALGYYNGKWEFLQDGEKIHRQLAQLGGLDALDVGRWRVSDDTVMH 60
           MEKYVAAMVLSAAGDALGYYNGKWEFLQDGEKIHRQLAQLGGLDALDVGRWRVSDDTVMH
Sbjct: 1   MEKYVAAMVLSAAGDALGYYNGKWEFLQDGEKIHRQLAQLGGLDALDVGRWRVSDDTVMH 60

Query: 61  LATAEALVEAGKAPKLTQLYYLLAKHYQDCMEDMDGRAPGGASVHNAMQLKPGKPNGWRI 120
           LATAEALVEAGKAPKLTQLYYLLAKHYQDCMEDMDGRAPGGASVHNAMQLKPGKPNGWRI
Sbjct: 61  LATAEALVEAGKAPKLTQLYYLLAKHYQDCMEDMDGRAPGGASVHNAMQLKPGKPNGWRI 120

Query: 121 PFNSHEGGCGAAMRAMCIGLRFPHHSQLDTLIQVSIESGRMTHHHPTGYLGALASALFTA 180
           PFNSHEGGCGAAMRAMCIGLRFPHHSQLDTLIQVSIESGRMTHHHPTGYLGALASALFTA
Sbjct: 121 PFNSHEGGCGAAMRAMCIGLRFPHHSQLDTLIQVSIESGRMTHHHPTGYLGALASALFTA 180

Query: 181 YAVNSRPPLQWGKGLMELLPEAKKYIVQSGYFVEENLQHWSYFQTKWENYLKLRGILDGE 240
           YAVNSRPPLQWGKGLMELLPEAKKYIVQSGYFVEENLQHWSYFQTKWENYLKLRGILDGE
Sbjct: 181 YAVNSRPPLQWGKGLMELLPEAKKYIVQSGYFVEENLQHWSYFQTKWENYLKLRGILDGE 240

Query: 241 SAPTFPESFGVKERDQFYTSLSYSGWGGSSGHDAPMIAYDAVLAAGDSWKELAHRAFFHG 300
           SAPTFPESFGVKERDQFYTSLSYSGWGGSSGHDAPMIAYDAVLAAGDSWKELAHRAFFHG
Sbjct: 241 SAPTFPESFGVKERDQFYTSLSYSGWGGSSGHDAPMIAYDAVLAAGDSWKELAHRAFFHG 300

Query: 301 GDSDSTAAIAGCWWGVMYGFKGVSPSNYEKLEYRNRLEETARALYSLGSKEDTVISL 357
           GDSDSTAAIAGCWWGVMYGFKGVSPSNYEKLEYRNRLEETARALYSLGSKEDTVISL
Sbjct: 301 GDSDSTAAIAGCWWGVMYGFKGVSPSNYEKLEYRNRLEETARALYSLGSKEDTVISL 357


>gi|21702735 ADP-ribosylhydrolase like 1 isoform 1 [Homo sapiens]
          Length = 354

 Score =  309 bits (792), Expect = 2e-84
 Identities = 163/355 (45%), Positives = 224/355 (63%), Gaps = 6/355 (1%)

Query: 1   MEKYVAAMVLSAAGDALGYYNGKWEFLQDGEKIHRQLAQLGGLD--ALDVGRWRVSDDTV 58
           MEK+ AAM+L + GDALGY N   E    G KI  +L + GGLD   L  G W VSD+T+
Sbjct: 1   MEKFKAAMLLGSVGDALGYRNVCKENSTVGMKIQEELQRSGGLDHLVLSPGEWPVSDNTI 60

Query: 59  MHLATAEALVEAGKAPKLTQLYYLLAKHYQDCMEDMDGRAPGGASVHNAMQLKPGKPN-G 117
           MH+ATAEAL        L  LY  + + Y + +E +  R P  A++    QLKP      
Sbjct: 61  MHIATAEALTTDYWC--LDDLYREMVRCYVEIVEKLPERRPDPATIEGCAQLKPNNYLLA 118

Query: 118 WRIPFNSHEGGCGAAMRAMCIGLRFPHHSQLDTLIQVSIESGRMTHHHPTGYLGALASAL 177
           W  PFN    G GAA +AMCIGLR+    +L+TLI+VS+E GRMTH+HPTG+LG+L +AL
Sbjct: 119 WHTPFNEKGSGFGAATKAMCIGLRYWKPERLETLIEVSVECGRMTHNHPTGFLGSLCTAL 178

Query: 178 FTAYAVNSRPPLQWGKGLMELLPEAKKYIVQSGYFVEENLQHWSYFQTKWENYLKLRGI- 236
           F ++A   +P +QWG+ ++  +P A++Y  ++     E  +HW YF+ KW+ YL+ R I 
Sbjct: 179 FVSFAAQGKPLVQWGRDMLRAVPLAEEYCRKTIRHTAEYQEHWFYFEAKWQFYLEERKIS 238

Query: 237 LDGESAPTFPESFGVKERDQFYTSLSYSGWGGSSGHDAPMIAYDAVLAAGDSWKELAHRA 296
            D E+   FP+++  +ER++ Y   S  G GG  GHDAPMIAYDA+LAAG+SW EL HRA
Sbjct: 239 KDSENKAIFPDNYDAEEREKTYRKWSSEGRGGRRGHDAPMIAYDALLAAGNSWTELCHRA 298

Query: 297 FFHGGDSDSTAAIAGCWWGVMYGFKGVSPSNYEKLEYRNRLEETARALYSLGSKE 351
            FHGG+S +T  IAGC +G++YG   V    Y+ LE + +LE+   ALY L ++E
Sbjct: 299 MFHGGESAATGTIAGCLFGLLYGLDLVPKGLYQDLEDKEKLEDLGAALYRLSTEE 353


>gi|40316946 ADP-ribosylhydrolase like 1 isoform 2 [Homo sapiens]
          Length = 272

 Score =  250 bits (639), Expect = 1e-66
 Identities = 122/271 (45%), Positives = 175/271 (64%), Gaps = 2/271 (0%)

Query: 83  LAKHYQDCMEDMDGRAPGGASVHNAMQLKPGKPN-GWRIPFNSHEGGCGAAMRAMCIGLR 141
           + + Y + +E +  R P  A++    QLKP      W  PFN    G GAA +AMCIGLR
Sbjct: 1   MVRCYVEIVEKLPERRPDPATIEGCAQLKPNNYLLAWHTPFNEKGSGFGAATKAMCIGLR 60

Query: 142 FPHHSQLDTLIQVSIESGRMTHHHPTGYLGALASALFTAYAVNSRPPLQWGKGLMELLPE 201
           +    +L+TLI+VS+E GRMTH+HPTG+LG+L +ALF ++A   +P +QWG+ ++  +P 
Sbjct: 61  YWKPERLETLIEVSVECGRMTHNHPTGFLGSLCTALFVSFAAQGKPLVQWGRDMLRAVPL 120

Query: 202 AKKYIVQSGYFVEENLQHWSYFQTKWENYLKLRGI-LDGESAPTFPESFGVKERDQFYTS 260
           A++Y  ++     E  +HW YF+ KW+ YL+ R I  D E+   FP+++  +ER++ Y  
Sbjct: 121 AEEYCRKTIRHTAEYQEHWFYFEAKWQFYLEERKISKDSENKAIFPDNYDAEEREKTYRK 180

Query: 261 LSYSGWGGSSGHDAPMIAYDAVLAAGDSWKELAHRAFFHGGDSDSTAAIAGCWWGVMYGF 320
            S  G GG  GHDAPMIAYDA+LAAG+SW EL HRA FHGG+S +T  IAGC +G++YG 
Sbjct: 181 WSSEGRGGRRGHDAPMIAYDALLAAGNSWTELCHRAMFHGGESAATGTIAGCLFGLLYGL 240

Query: 321 KGVSPSNYEKLEYRNRLEETARALYSLGSKE 351
             V    Y+ LE + +LE+   ALY L ++E
Sbjct: 241 DLVPKGLYQDLEDKEKLEDLGAALYRLSTEE 271


>gi|8923417 ADP-ribosylhydrolase like 2 [Homo sapiens]
          Length = 363

 Score = 32.0 bits (71), Expect = 0.87
 Identities = 71/319 (22%), Positives = 120/319 (37%), Gaps = 54/319 (16%)

Query: 54  SDDTVMHLATAEALVEAGKAPKLTQLYYLLAKHYQDCMEDMD-GRAPGGASVHNAMQLKP 112
           +DDT M    A ALV++  A +      +  +  Q+  +D D G   G  +V   + L P
Sbjct: 76  TDDTAM----ARALVQSLLAKEAFDEVDMAHRFAQEYKKDPDRGYGAGVVTVFKKL-LNP 130

Query: 113 GKPNGW---RIPFNSHEG-GCGAAMRAMCIGLRFPHHSQLDTLIQVSIESGRMTHHHPTG 168
              + +   R  FN     G G AMR   I L +   S +  + + +  S ++TH    G
Sbjct: 131 KCRDVFEPARAQFNGKGSYGNGGAMRVAGISLAY---SSVQDVQKFARLSAQLTHASSLG 187

Query: 169 YLGALASALFTAYAVNSRPPLQWGKGLMELLPEAKKYIVQSGYFVEENLQHWSYFQTKWE 228
           Y GA+  AL    A+                         S +F+++ L H    +   +
Sbjct: 188 YNGAILQALAVHLALQGES--------------------SSEHFLKQLLGHMEDLEGDAQ 227

Query: 229 NYLKLRGILDGESAPTFPESFGVKERDQFYTSLSYS--------GWGGSSGHDAPMIAY- 279
           + L  R +   E     P S  +K+  +     S +        G G ++    P   Y 
Sbjct: 228 SVLDARELGMEER----PYSSRLKKIGELLDQASVTREEVVSELGNGIAAFESVPTAIYC 283

Query: 280 --------DAVLAAGDSWKELAHRAFFHGGDSDSTAAIAGCWWGVMYGFKGVSPSNYEKL 331
                     + +A +S +     +   GGD+D+ A +AG   G  YG   V  S  +  
Sbjct: 284 FLRCMEPDPEIPSAFNSLQRTLIYSISLGGDTDTIATMAGAIAGAYYGMDQVPESWQQSC 343

Query: 332 EYRNRLEETARALYSLGSK 350
           E     +  A++L+ +  K
Sbjct: 344 EGYEETDILAQSLHRVFQK 362


>gi|239743879 PREDICTED: hypothetical protein XP_002342985 [Homo
           sapiens]
          Length = 216

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 17/56 (30%), Positives = 21/56 (37%), Gaps = 2/56 (3%)

Query: 92  EDMDGRAPGGASVHNAMQLKPGKPNGWRIPFNSHEGGCGAAMRAMCIGLRFPHHSQ 147
           ED DG  PG  +    +    G P+GW  P+      C  A    C G   P   Q
Sbjct: 72  EDGDGEGPGDVTA--GVSRAAGSPSGWEAPWVQQPRCCRRATPVCCAGQGPPRSLQ 125


>gi|7706671 peroxisomal biogenesis factor 5-like [Homo sapiens]
          Length = 626

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 15/80 (18%), Positives = 32/80 (40%)

Query: 190 QWGKGLMELLPEAKKYIVQSGYFVEENLQHWSYFQTKWENYLKLRGILDGESAPTFPESF 249
           +WG  L+      ++   ++   VE + + W   Q +WE   +   I + + A       
Sbjct: 250 RWGSALLSRNHSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQEAQNQVTIS 309

Query: 250 GVKERDQFYTSLSYSGWGGS 269
             ++   F+T   +  W G+
Sbjct: 310 ASEKGYYFHTENPFKDWPGA 329


>gi|42476130 ubiquitin interaction motif containing 1 [Homo sapiens]
          Length = 719

 Score = 28.9 bits (63), Expect = 7.4
 Identities = 37/146 (25%), Positives = 62/146 (42%), Gaps = 11/146 (7%)

Query: 193 KGLMELLPEA--KKYIVQSGYFVEENLQHWSYFQ-TKWENYLKLRGILDGESAPTFPESF 249
           +G+ +L+P +  K   +  G   EE  + W + + T+ E      G  D  S P F E+ 
Sbjct: 154 EGIWQLVPPSLFKGSHISQGNEAEEREEPWDHTEKTEEEPVSGSSGSWDQSSQPVF-ENV 212

Query: 250 GVKERDQFYT-SLSYSGWGG---SSGHDAPMIAYDAVLAAGDSWKELAHRAFFHGGDSDS 305
            VK  D+    S  ++  G    S+G  +  +   AV  +GD+ +          G  D 
Sbjct: 213 NVKSFDRCTGHSAEHTQCGKPQESTGRGSAFLK--AVQGSGDTSRHCLPTLADAKGLQD- 269

Query: 306 TAAIAGCWWGVMYGFKGVSPSNYEKL 331
           T      +WG+ +   GV P+ Y K+
Sbjct: 270 TGGTVNYFWGIPFCPDGVDPNQYTKV 295


>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3874

 Score = 28.5 bits (62), Expect = 9.7
 Identities = 19/44 (43%), Positives = 24/44 (54%), Gaps = 3/44 (6%)

Query: 40   LGGLDALDVGRWRVSDDTVMHLATAEALVEAGKAPKLTQLYYLL 83
            L G   L +GR R+SD  +    T EAL  AG+  KL QL  L+
Sbjct: 1796 LPGTHTLQLGRARLSDSGMY---TCEALNAAGRDQKLVQLSVLV 1836


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score = 28.5 bits (62), Expect = 9.7
 Identities = 19/44 (43%), Positives = 24/44 (54%), Gaps = 3/44 (6%)

Query: 40   LGGLDALDVGRWRVSDDTVMHLATAEALVEAGKAPKLTQLYYLL 83
            L G   L +GR R+SD  +    T EAL  AG+  KL QL  L+
Sbjct: 2987 LPGTHTLQLGRARLSDSGMY---TCEALNAAGRDQKLVQLSVLV 3027


>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3783

 Score = 28.5 bits (62), Expect = 9.7
 Identities = 19/44 (43%), Positives = 24/44 (54%), Gaps = 3/44 (6%)

Query: 40   LGGLDALDVGRWRVSDDTVMHLATAEALVEAGKAPKLTQLYYLL 83
            L G   L +GR R+SD  +    T EAL  AG+  KL QL  L+
Sbjct: 1705 LPGTHTLQLGRARLSDSGMY---TCEALNAAGRDQKLVQLSVLV 1745


>gi|197313787 desmoglein 4 isoform 1 [Homo sapiens]
          Length = 1059

 Score = 28.5 bits (62), Expect = 9.7
 Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 8/62 (12%)

Query: 204 KYIVQSGYFVEENLQHWSYFQTKW---ENYLKLRGILDGESAPTFPESFGVKERDQFYTS 260
           +Y++ SG     N  +W   QT     E  LK+  +LD E AP    S GVK +  F+ S
Sbjct: 306 QYLILSG-----NDGNWFDIQTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHYS 360

Query: 261 LS 262
           ++
Sbjct: 361 VA 362


>gi|29789445 desmoglein 4 isoform 2 [Homo sapiens]
          Length = 1040

 Score = 28.5 bits (62), Expect = 9.7
 Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 8/62 (12%)

Query: 204 KYIVQSGYFVEENLQHWSYFQTKW---ENYLKLRGILDGESAPTFPESFGVKERDQFYTS 260
           +Y++ SG     N  +W   QT     E  LK+  +LD E AP    S GVK +  F+ S
Sbjct: 306 QYLILSG-----NDGNWFDIQTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHYS 360

Query: 261 LS 262
           ++
Sbjct: 361 VA 362


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,354,669
Number of Sequences: 37866
Number of extensions: 643275
Number of successful extensions: 1485
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1473
Number of HSP's gapped (non-prelim): 14
length of query: 357
length of database: 18,247,518
effective HSP length: 103
effective length of query: 254
effective length of database: 14,347,320
effective search space: 3644219280
effective search space used: 3644219280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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