Guide to the Human Genome
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Search of human proteins with 4507371

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507371 tafazzin isoform 1 [Homo sapiens]
         (292 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507371 tafazzin isoform 1 [Homo sapiens]                          622   e-179
gi|31317261 tafazzin isoform 3 [Homo sapiens]                         583   e-167
gi|31317259 tafazzin isoform 2 [Homo sapiens]                         545   e-155
gi|31317263 tafazzin isoform 4 [Homo sapiens]                         506   e-144
gi|208431776 phosphatidylinositol-4-phosphate 5-kinase, type I, ...    32   0.51 
gi|116268093 taste receptor, type 2, member 41 [Homo sapiens]          30   3.3  
gi|5454102 transforming, acidic coiled-coil containing protein 3...    29   4.3  
gi|156564405 catalytic phosphatidylinositol 3-kinase delta [Homo...    28   7.3  
gi|13376146 zinc finger and BTB domain containing 3 [Homo sapiens]     28   7.3  
gi|42794273 F-box and leucine-rich repeat protein 22 [Homo sapiens]    28   7.3  

>gi|4507371 tafazzin isoform 1 [Homo sapiens]
          Length = 292

 Score =  622 bits (1605), Expect = e-179
 Identities = 292/292 (100%), Positives = 292/292 (100%)

Query: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60
           MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA
Sbjct: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60

Query: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120
           TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP
Sbjct: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120

Query: 121 VCRGAEFFQAENEGKGVLDTGRHMPGAGKRREKGDGVYQKGMDFILEKLNHGDWVHIFPE 180
           VCRGAEFFQAENEGKGVLDTGRHMPGAGKRREKGDGVYQKGMDFILEKLNHGDWVHIFPE
Sbjct: 121 VCRGAEFFQAENEGKGVLDTGRHMPGAGKRREKGDGVYQKGMDFILEKLNHGDWVHIFPE 180

Query: 181 GKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIG 240
           GKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIG
Sbjct: 181 GKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIG 240

Query: 241 KPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR 292
           KPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR
Sbjct: 241 KPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR 292


>gi|31317261 tafazzin isoform 3 [Homo sapiens]
          Length = 278

 Score =  583 bits (1504), Expect = e-167
 Identities = 278/292 (95%), Positives = 278/292 (95%), Gaps = 14/292 (4%)

Query: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60
           MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA
Sbjct: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60

Query: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120
           TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP
Sbjct: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120

Query: 121 VCRGAEFFQAENEGKGVLDTGRHMPGAGKRREKGDGVYQKGMDFILEKLNHGDWVHIFPE 180
           VCRGAEFFQAENEGKGVLDTGRHMPGAGKRREKGDGVYQKGMDFILEKLNHGDWVHIFPE
Sbjct: 121 VCRGAEFFQAENEGKGVLDTGRHMPGAGKRREKGDGVYQKGMDFILEKLNHGDWVHIFPE 180

Query: 181 GKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIG 240
                         GIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIG
Sbjct: 181 --------------GIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIG 226

Query: 241 KPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR 292
           KPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR
Sbjct: 227 KPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR 278


>gi|31317259 tafazzin isoform 2 [Homo sapiens]
          Length = 262

 Score =  545 bits (1404), Expect = e-155
 Identities = 262/292 (89%), Positives = 262/292 (89%), Gaps = 30/292 (10%)

Query: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60
           MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA
Sbjct: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60

Query: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120
           TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP
Sbjct: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120

Query: 121 VCRGAEFFQAENEGKGVLDTGRHMPGAGKRREKGDGVYQKGMDFILEKLNHGDWVHIFPE 180
           VCRG                              DGVYQKGMDFILEKLNHGDWVHIFPE
Sbjct: 121 VCRG------------------------------DGVYQKGMDFILEKLNHGDWVHIFPE 150

Query: 181 GKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIG 240
           GKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIG
Sbjct: 151 GKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIG 210

Query: 241 KPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR 292
           KPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR
Sbjct: 211 KPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR 262


>gi|31317263 tafazzin isoform 4 [Homo sapiens]
          Length = 248

 Score =  506 bits (1303), Expect = e-144
 Identities = 248/292 (84%), Positives = 248/292 (84%), Gaps = 44/292 (15%)

Query: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60
           MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA
Sbjct: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60

Query: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120
           TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP
Sbjct: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120

Query: 121 VCRGAEFFQAENEGKGVLDTGRHMPGAGKRREKGDGVYQKGMDFILEKLNHGDWVHIFPE 180
           VCR                              GDGVYQKGMDFILEKLNHGDWVHIFPE
Sbjct: 121 VCR------------------------------GDGVYQKGMDFILEKLNHGDWVHIFPE 150

Query: 181 GKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIG 240
                         GIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIG
Sbjct: 151 --------------GIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIG 196

Query: 241 KPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR 292
           KPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR
Sbjct: 197 KPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR 248


>gi|208431776 phosphatidylinositol-4-phosphate 5-kinase, type I,
           alpha isoform 4 [Homo sapiens]
          Length = 500

 Score = 32.3 bits (72), Expect = 0.51
 Identities = 33/116 (28%), Positives = 47/116 (40%), Gaps = 26/116 (22%)

Query: 126 EFFQAENEGKGVLDTGRHMPGAGKRREKGDGV--YQKGMDFI-----LEKLNH------- 171
           E  Q E    G ++T  HM G   R  KG+ +  Y   +D +     ++KL H       
Sbjct: 352 ESIQGEARRGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVH 411

Query: 172 -GDWVHIFPEGKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPP 226
            GD V +   G    +  F RF          C+     +P  H+G  DVLP +PP
Sbjct: 412 DGDTVSVHRPGFY--AERFQRFM---------CNTVFKKIPCVHLGRPDVLPQTPP 456


>gi|116268093 taste receptor, type 2, member 41 [Homo sapiens]
          Length = 307

 Score = 29.6 bits (65), Expect = 3.3
 Identities = 14/36 (38%), Positives = 18/36 (50%), Gaps = 2/36 (5%)

Query: 3   LHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKY 38
           L +KW FP   P  W L  SV++  + T   FW  Y
Sbjct: 120 LWLKWRFPGWVP--WLLLGSVLISFIITLLFFWVNY 153


>gi|5454102 transforming, acidic coiled-coil containing protein 3
           [Homo sapiens]
          Length = 838

 Score = 29.3 bits (64), Expect = 4.3
 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 11/65 (16%)

Query: 221 LPNSPPYFPRFGQKITVLIGKPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQ 280
           +P  PP  P  G       G P S  P+++ L+   K    + KA     QEE + L+++
Sbjct: 613 VPGPPPGVPAPG-------GPPLSTGPIVDLLQYSQKDLDAVVKAT----QEENRELRSR 661

Query: 281 AEQLH 285
            E+LH
Sbjct: 662 CEELH 666


>gi|156564405 catalytic phosphatidylinositol 3-kinase delta [Homo
           sapiens]
          Length = 1044

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 4/38 (10%)

Query: 156 GVYQKGMDFILEKLNHGDWVHIFPEGKVNMSSEFLRFK 193
           G+ ++ + FIL      D+VH+  +GK N S +F RF+
Sbjct: 924 GINRERVPFILTY----DFVHVIQQGKTNNSEKFERFR 957


>gi|13376146 zinc finger and BTB domain containing 3 [Homo
          sapiens]
          Length = 574

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 10/62 (16%)

Query: 6  KWPFPAVPPLTWTLASSVVMGLVGTY------SCFWTKYMNHLTV----HNREVLYELIE 55
          KW   A P   W    S++ G VG Y        FW  + +  T+    H++++L  L E
Sbjct: 7  KWGVEASPGKAWERKRSLLRGAVGRYRGATGGDLFWAPFPSWGTMEFPEHSQQLLQSLRE 66

Query: 56 KR 57
          +R
Sbjct: 67 QR 68


>gi|42794273 F-box and leucine-rich repeat protein 22 [Homo
          sapiens]
          Length = 241

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 3/54 (5%)

Query: 41 HLTVHNREVLYEL---IEKRGPATPLITVSNHQSCMDDPHLWGILKLRHIWNLK 91
          H+T  NRE L  L   ++K    +   T S      +DP LW +L  R +  L+
Sbjct: 2  HITQLNRECLLHLFSFLDKDSRKSLARTCSQLHDVFEDPALWSLLHFRSLTELQ 55


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.140    0.463 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,889,472
Number of Sequences: 37866
Number of extensions: 601008
Number of successful extensions: 1356
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1346
Number of HSP's gapped (non-prelim): 13
length of query: 292
length of database: 18,247,518
effective HSP length: 101
effective length of query: 191
effective length of database: 14,423,052
effective search space: 2754802932
effective search space used: 2754802932
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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