Search of human proteins with 4507201

Search of human proteins with 4507201

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507201 steroid-5-alpha-reductase 1 [Homo sapiens]
         (259 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507201 steroid-5-alpha-reductase 1 [Homo sapiens]                 546   e-156
gi|39812447 3-oxo-5 alpha-steroid 4-dehydrogenase 2 [Homo sapiens]    238   4e-63
gi|239751670 PREDICTED: similar to hCG16318 [Homo sapiens]             59   3e-09
gi|24475816 glycoprotein, synaptic 2 [Homo sapiens]                    55   5e-08
gi|13375785 steroid 5 alpha-reductase 3 [Homo sapiens]                 50   1e-06
gi|58332438 steroid 5 alpha-reductase 2-like 2 [Homo sapiens]          39   0.006
gi|18450278 dipeptidyl peptidase 8 isoform 2 [Homo sapiens]            30   2.1  
gi|37577089 dipeptidyl peptidase 8 isoform 3 [Homo sapiens]            30   2.1  
gi|37577091 dipeptidyl peptidase 8 isoform 4 [Homo sapiens]            30   2.1  
gi|18450280 dipeptidyl peptidase 8 isoform 1 [Homo sapiens]            30   2.1  
gi|114205383 secretin receptor precursor [Homo sapiens]                28   6.1  

>gi|4507201 steroid-5-alpha-reductase 1 [Homo sapiens]
          Length = 259

 Score =  546 bits (1406), Expect = e-156
 Identities = 259/259 (100%), Positives = 259/259 (100%)

Query: 1   MATATGVAEERLLAALAYLQCAVGCAVFARNRQTNSVYGRHALPSHRLRVPARAAWVVQE 60
           MATATGVAEERLLAALAYLQCAVGCAVFARNRQTNSVYGRHALPSHRLRVPARAAWVVQE
Sbjct: 1   MATATGVAEERLLAALAYLQCAVGCAVFARNRQTNSVYGRHALPSHRLRVPARAAWVVQE 60

Query: 61  LPSLALPLYQYASESAPRLRSAPNCILLAMFLVHYGHRCLIYPFLMRGGKPMPLLACTMA 120
           LPSLALPLYQYASESAPRLRSAPNCILLAMFLVHYGHRCLIYPFLMRGGKPMPLLACTMA
Sbjct: 61  LPSLALPLYQYASESAPRLRSAPNCILLAMFLVHYGHRCLIYPFLMRGGKPMPLLACTMA 120

Query: 121 IMFCTCNGYLQSRYLSHCAVYADDWVTDPRFLIGFGLWLTGMLINIHSDHILRNLRKPGD 180
           IMFCTCNGYLQSRYLSHCAVYADDWVTDPRFLIGFGLWLTGMLINIHSDHILRNLRKPGD
Sbjct: 121 IMFCTCNGYLQSRYLSHCAVYADDWVTDPRFLIGFGLWLTGMLINIHSDHILRNLRKPGD 180

Query: 181 TGYKIPRGGLFEYVTAANYFGEIMEWCGYALASWSVQGAAFAFFTFCFLSGRAKEHHEWY 240
           TGYKIPRGGLFEYVTAANYFGEIMEWCGYALASWSVQGAAFAFFTFCFLSGRAKEHHEWY
Sbjct: 181 TGYKIPRGGLFEYVTAANYFGEIMEWCGYALASWSVQGAAFAFFTFCFLSGRAKEHHEWY 240

Query: 241 LRKFEEYPKFRKIIIPFLF 259
           LRKFEEYPKFRKIIIPFLF
Sbjct: 241 LRKFEEYPKFRKIIIPFLF 259


>gi|39812447 3-oxo-5 alpha-steroid 4-dehydrogenase 2 [Homo sapiens]
          Length = 254

 Score =  238 bits (607), Expect = 4e-63
 Identities = 119/226 (52%), Positives = 150/226 (66%), Gaps = 4/226 (1%)

Query: 36  SVYGRH--ALPSHRLRVPARAAWVVQELPSLALPLYQYASESAPRLRSAPNCILLAMFLV 93
           S YG+H  +L     R+PARAAW +QELPS A+P    A +    L   P  +LL +F +
Sbjct: 31  SGYGKHTESLKPAATRLPARAAWFLQELPSFAVPAGILARQPLS-LFGPPGTVLLGLFCL 89

Query: 94  HYGHRCLIYPFLMRGGKPMPLLACTMAIMFCTCNGYLQSRYLSHCAVYADDWVTDPRFLI 153
           HY HR  +Y  L RG +P P +       FCT NG LQ  YL +CA Y D W TD RF +
Sbjct: 90  HYFHRTFVYSLLNRG-RPYPAILILRGTAFCTGNGVLQGYYLIYCAEYPDGWYTDIRFSL 148

Query: 154 GFGLWLTGMLINIHSDHILRNLRKPGDTGYKIPRGGLFEYVTAANYFGEIMEWCGYALAS 213
           G  L++ GM INIHSD+ILR LRKPG+  Y+IP+GGLF YV+ AN+ GEI+EW GYALA+
Sbjct: 149 GVFLFILGMGINIHSDYILRQLRKPGEISYRIPQGGLFTYVSGANFLGEIIEWIGYALAT 208

Query: 214 WSVQGAAFAFFTFCFLSGRAKEHHEWYLRKFEEYPKFRKIIIPFLF 259
           WS+   AFAFF+ CFL  RA  HH +YL+ FE+YPK RK +IPF+F
Sbjct: 209 WSLPALAFAFFSLCFLGLRAFHHHRFYLKMFEDYPKSRKALIPFIF 254


>gi|239751670 PREDICTED: similar to hCG16318 [Homo sapiens]
          Length = 166

 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 48/169 (28%), Positives = 71/169 (42%), Gaps = 11/169 (6%)

Query: 96  GHRCLIYPFLMRGGKPMPLLACTMAIMFCTCNGYLQSRYLSHCAVYADDWVTDPRFLIGF 155
           G  CL+  +      P P   CT    F     Y    Y++H  +Y        +  +  
Sbjct: 2   GSICLVRCWPKSHPCPAPFQNCTYYWGFAAWMAY----YINH-PLYTPPTYGAQQVKLAL 56

Query: 156 GLWLTGMLINIHSDHILRNLRKPGDTGYKIPRGG------LFEYVTAANYFGEIMEWCGY 209
            +++   L N      LR+LR  G    KIP         LF  V+  NY  E+  W G+
Sbjct: 57  AIFVICQLGNFSIHMALRDLRPAGSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGF 116

Query: 210 ALASWSVQGAAFAFFTFCFLSGRAKEHHEWYLRKFEEYPKFRKIIIPFL 258
           A+ +  +  A F+   F  ++  AK  H  YL++F +YP  R  IIPFL
Sbjct: 117 AIMTQCLPVALFSLVGFTQMTIWAKGKHRSYLKEFRDYPPLRMPIIPFL 165


>gi|24475816 glycoprotein, synaptic 2 [Homo sapiens]
          Length = 308

 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 39/131 (29%), Positives = 60/131 (45%), Gaps = 7/131 (5%)

Query: 134 YLSHCAVYADDWVTDPRFLIGFGLWLTGMLINIHSDHILRNLRKPGDTGYKIPRGG---- 189
           Y++H  +Y        +  +   +++   L N      LR+LR  G    KIP       
Sbjct: 178 YINH-PLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLRPAGSKTRKIPYPTKNPF 236

Query: 190 --LFEYVTAANYFGEIMEWCGYALASWSVQGAAFAFFTFCFLSGRAKEHHEWYLRKFEEY 247
             LF  V+  NY  E+  W G+A+ +  +  A F+   F  ++  AK  H  YL++F +Y
Sbjct: 237 TWLFLLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIWAKGKHRSYLKEFRDY 296

Query: 248 PKFRKIIIPFL 258
           P  R  IIPFL
Sbjct: 297 PPLRMPIIPFL 307


>gi|13375785 steroid 5 alpha-reductase 3 [Homo sapiens]
          Length = 318

 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 37/102 (36%), Positives = 48/102 (47%), Gaps = 19/102 (18%)

Query: 171 ILRNLRKPG-----DTGYKIPRGGLFEYVTAANYFGEIMEWCGYALA------SW--SVQ 217
           IL NLRK          ++IP G  FEYV++ NY  E+M +   A+       +W   V 
Sbjct: 223 ILGNLRKNKAGVVIHCNHRIPFGDWFEYVSSPNYLAELMIYVSMAVTFGFHNLTWWLVVT 282

Query: 218 GAAFAFFTFCFLSGRAKEHHEWYLRKFEEYPKFRKIIIPFLF 259
              F      FLS      H++Y  KF  YPK RK  +PFLF
Sbjct: 283 NVFFNQALSAFLS------HQFYKSKFVSYPKHRKAFLPFLF 318


>gi|58332438 steroid 5 alpha-reductase 2-like 2 [Homo sapiens]
          Length = 363

 Score = 38.5 bits (88), Expect = 0.006
 Identities = 20/69 (28%), Positives = 34/69 (49%)

Query: 190 LFEYVTAANYFGEIMEWCGYALASWSVQGAAFAFFTFCFLSGRAKEHHEWYLRKFEEYPK 249
           +F  V+  NY  EI  W  + + + ++    F       +S  A++ H+ YLRKF  Y  
Sbjct: 294 MFFLVSCPNYTYEIGSWISFTVMTQTLPVGIFTLLMSIQMSLWAQKKHKIYLRKFNSYIH 353

Query: 250 FRKIIIPFL 258
            +  +IPF+
Sbjct: 354 RKSAMIPFI 362


>gi|18450278 dipeptidyl peptidase 8 isoform 2 [Homo sapiens]
          Length = 782

 Score = 30.0 bits (66), Expect = 2.1
 Identities = 18/43 (41%), Positives = 24/43 (55%), Gaps = 4/43 (9%)

Query: 76  APRLRSAPNCILLAM-FL---VHYGHRCLIYPFLMRGGKPMPL 114
           A +  S PN +LL   FL   VH+ H  ++  FL+R GKP  L
Sbjct: 699 AEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDL 741


>gi|37577089 dipeptidyl peptidase 8 isoform 3 [Homo sapiens]
          Length = 898

 Score = 30.0 bits (66), Expect = 2.1
 Identities = 18/43 (41%), Positives = 24/43 (55%), Gaps = 4/43 (9%)

Query: 76  APRLRSAPNCILLAM-FL---VHYGHRCLIYPFLMRGGKPMPL 114
           A +  S PN +LL   FL   VH+ H  ++  FL+R GKP  L
Sbjct: 815 AEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDL 857


>gi|37577091 dipeptidyl peptidase 8 isoform 4 [Homo sapiens]
          Length = 847

 Score = 30.0 bits (66), Expect = 2.1
 Identities = 18/43 (41%), Positives = 24/43 (55%), Gaps = 4/43 (9%)

Query: 76  APRLRSAPNCILLAM-FL---VHYGHRCLIYPFLMRGGKPMPL 114
           A +  S PN +LL   FL   VH+ H  ++  FL+R GKP  L
Sbjct: 764 AEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDL 806


>gi|18450280 dipeptidyl peptidase 8 isoform 1 [Homo sapiens]
          Length = 882

 Score = 30.0 bits (66), Expect = 2.1
 Identities = 18/43 (41%), Positives = 24/43 (55%), Gaps = 4/43 (9%)

Query: 76  APRLRSAPNCILLAM-FL---VHYGHRCLIYPFLMRGGKPMPL 114
           A +  S PN +LL   FL   VH+ H  ++  FL+R GKP  L
Sbjct: 799 AEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDL 841


>gi|114205383 secretin receptor precursor [Homo sapiens]
          Length = 440

 Score = 28.5 bits (62), Expect = 6.1
 Identities = 16/45 (35%), Positives = 24/45 (53%), Gaps = 6/45 (13%)

Query: 209 YALASWSVQGAAFAFFTFCFLSGRA-----KEHHEWYLRKFEEYP 248
           + LA  S QG   A   +CFL+G       K+  +W+LR+F  +P
Sbjct: 372 FELALGSFQGLVVAVL-YCFLNGEVQLEVQKKWQQWHLREFPLHP 415


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.330    0.142    0.475 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,341,319
Number of Sequences: 37866
Number of extensions: 459828
Number of successful extensions: 971
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 962
Number of HSP's gapped (non-prelim): 11
length of query: 259
length of database: 18,247,518
effective HSP length: 100
effective length of query: 159
effective length of database: 14,460,918
effective search space: 2299285962
effective search space used: 2299285962
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.