Guide to the Human Genome
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Search of human proteins with 4507149

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507149 superoxide dismutase 1, soluble [Homo sapiens]
         (154 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507149 superoxide dismutase 1, soluble [Homo sapiens]             320   2e-88
gi|4826665 copper chaperone for superoxide dismutase [Homo sapiens]   143   5e-35
gi|118582275 superoxide dismutase 3, extracellular precursor [Ho...   105   2e-23
gi|109715827 zinc finger protein 35 [Homo sapiens]                     28   2.4  
gi|36029914 valosin containing protein (p97)/p47 complex interac...    27   6.9  
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi...    27   6.9  
gi|222537754 hypothetical protein LOC375337 [Homo sapiens]             27   9.1  
gi|188595687 gamma filamin isoform b [Homo sapiens]                    27   9.1  
gi|116805322 gamma filamin isoform a [Homo sapiens]                    27   9.1  
gi|239746650 PREDICTED: hypothetical protein [Homo sapiens]            27   9.1  
gi|31543806 thrombospondin 4 precursor [Homo sapiens]                  27   9.1  
gi|13375654 PTIP-associated 1 protein [Homo sapiens]                   27   9.1  

>gi|4507149 superoxide dismutase 1, soluble [Homo sapiens]
          Length = 154

 Score =  320 bits (821), Expect = 2e-88
 Identities = 154/154 (100%), Positives = 154/154 (100%)

Query: 1   MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTS 60
           MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTS
Sbjct: 1   MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTS 60

Query: 61  AGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVV 120
           AGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVV
Sbjct: 61  AGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVV 120

Query: 121 HEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ 154
           HEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ
Sbjct: 121 HEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ 154


>gi|4826665 copper chaperone for superoxide dismutase [Homo sapiens]
          Length = 274

 Score =  143 bits (361), Expect = 5e-35
 Identities = 73/146 (50%), Positives = 94/146 (64%), Gaps = 4/146 (2%)

Query: 5   AVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPH 64
           AV +L G G VQG++ F Q      + + G+I GL  GLHG HVH++GD T  C S G H
Sbjct: 89  AVAILGGPGTVQGVVRFLQLTPERCL-IEGTIDGLEPGLHGLHVHQYGDLTNNCNSCGNH 147

Query: 65  FNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKA 124
           FNP    HGGP+D +RH GDLGNV AD DG A   +ED  + +     +IGR+L++ E  
Sbjct: 148 FNPDGASHGGPQDSDRHRGDLGNVRADADGRAIFRMEDEQLKVWD---VIGRSLIIDEGE 204

Query: 125 DDLGKGGNEESTKTGNAGSRLACGVI 150
           DDLG+GG+  S  TGN+G RLACG+I
Sbjct: 205 DDLGRGGHPLSKITGNSGERLACGII 230


>gi|118582275 superoxide dismutase 3, extracellular precursor [Homo
           sapiens]
          Length = 240

 Score =  105 bits (261), Expect = 2e-23
 Identities = 57/142 (40%), Positives = 78/142 (54%), Gaps = 11/142 (7%)

Query: 15  VQGIINFEQKESNGPVKVWGSIKGL----TEGLHGFHVHEFGDNTAGCTSAGPHFNPLSR 70
           V G++ F Q      +  + +++G            HVH+FGD + GC S GPH+NPL+ 
Sbjct: 78  VTGVVLFRQLAPRAKLDAFFALEGFPTEPNSSSRAIHVHQFGDLSQGCESTGPHYNPLAV 137

Query: 71  KHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKG 130
            H       +H GD GN  A +DG           SL+G H I+GR +VVH   DDLG+G
Sbjct: 138 PH------PQHPGDFGNF-AVRDGSLWRYRAGLAASLAGPHSIVGRAVVVHAGEDDLGRG 190

Query: 131 GNEESTKTGNAGSRLACGVIGI 152
           GN+ S + GNAG RLAC V+G+
Sbjct: 191 GNQASVENGNAGRRLACCVVGV 212


>gi|109715827 zinc finger protein 35 [Homo sapiens]
          Length = 527

 Score = 28.5 bits (62), Expect = 2.4
 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 13/54 (24%)

Query: 13 GPVQGIINFEQKESNGP------------VKVWGSIKGLTEGLHGFHVHEFGDN 54
          GPV+ +   E++E N P            +KVW  ++GL  GL G    E G N
Sbjct: 15 GPVK-VKKEEEEEENFPGQASSQQVHSENIKVWAPVQGLQTGLDGSEEEEKGQN 67


>gi|36029914 valosin containing protein (p97)/p47 complex interacting
            protein 1 [Homo sapiens]
          Length = 1222

 Score = 26.9 bits (58), Expect = 6.9
 Identities = 15/52 (28%), Positives = 26/52 (50%), Gaps = 2/52 (3%)

Query: 22   EQKESNGPVKVW--GSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRK 71
            E   S+G +K+   G +K  +E LH     +   ++ G  S  PH +P +R+
Sbjct: 996  ESSPSHGLLKLGSGGVVKKKSEQLHNVTAFQGKGHSLGTASGNPHLDPRARE 1047


>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
           sapiens]
          Length = 783

 Score = 26.9 bits (58), Expect = 6.9
 Identities = 17/59 (28%), Positives = 23/59 (38%), Gaps = 1/59 (1%)

Query: 22  EQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEER 80
           EQ E  GP + +G  +G  EG  GF     G+        G    P  ++ GG     R
Sbjct: 710 EQPELEGPREGYGGFRGQREGSRGFRGQRDGNRRFRGQREGSR-GPRGQRSGGGNKSNR 767


>gi|222537754 hypothetical protein LOC375337 [Homo sapiens]
          Length = 1692

 Score = 26.6 bits (57), Expect = 9.1
 Identities = 12/41 (29%), Positives = 23/41 (56%), Gaps = 1/41 (2%)

Query: 66  NPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVIS 106
           +P   K G       HV + GN+ ++K+ VA +++E++  S
Sbjct: 770 SPSFTKQGNNSKPSNHVSEPGNIVSNKE-VASLTVENNAFS 809


>gi|188595687 gamma filamin isoform b [Homo sapiens]
          Length = 2692

 Score = 26.6 bits (57), Expect = 9.1
 Identities = 15/63 (23%), Positives = 27/63 (42%), Gaps = 4/63 (6%)

Query: 63   PHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHE 122
            P F+P   +  GP  E   VG+    T D     +  +   ++S +G    +   +++H 
Sbjct: 1151 PVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAG----VKAEVLIHN 1206

Query: 123  KAD 125
             AD
Sbjct: 1207 NAD 1209


>gi|116805322 gamma filamin isoform a [Homo sapiens]
          Length = 2725

 Score = 26.6 bits (57), Expect = 9.1
 Identities = 15/63 (23%), Positives = 27/63 (42%), Gaps = 4/63 (6%)

Query: 63   PHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHE 122
            P F+P   +  GP  E   VG+    T D     +  +   ++S +G    +   +++H 
Sbjct: 1151 PVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAG----VKAEVLIHN 1206

Query: 123  KAD 125
             AD
Sbjct: 1207 NAD 1209


>gi|239746650 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 486

 Score = 26.6 bits (57), Expect = 9.1
 Identities = 13/46 (28%), Positives = 24/46 (52%)

Query: 90  ADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEES 135
           A++D V D++ ED++  ++ D      T  +H   D +    NE+S
Sbjct: 230 ANEDSVYDIANEDAIYDIANDTVQGTLTRTLHANVDTVHDIANEDS 275


>gi|31543806 thrombospondin 4 precursor [Homo sapiens]
          Length = 961

 Score = 26.6 bits (57), Expect = 9.1
 Identities = 14/42 (33%), Positives = 23/42 (54%), Gaps = 3/42 (7%)

Query: 76  KDEERHVGDLGNVTADKDGVADVSIEDS---VISLSGDHCII 114
           KD  ++V + G   AD+DG+ D   ED+    I    D+C++
Sbjct: 484 KDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVL 525


>gi|13375654 PTIP-associated 1 protein [Homo sapiens]
          Length = 254

 Score = 26.6 bits (57), Expect = 9.1
 Identities = 10/20 (50%), Positives = 15/20 (75%)

Query: 123 KADDLGKGGNEESTKTGNAG 142
           KA+D G+GG EE+ + G+ G
Sbjct: 45  KAEDEGEGGREETEREGSGG 64


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.136    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,639,609
Number of Sequences: 37866
Number of extensions: 301134
Number of successful extensions: 442
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 433
Number of HSP's gapped (non-prelim): 12
length of query: 154
length of database: 18,247,518
effective HSP length: 93
effective length of query: 61
effective length of database: 14,725,980
effective search space: 898284780
effective search space used: 898284780
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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