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Search of human proteins with 4506271
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506271 parathyroid hormone receptor 1 precursor [Homo
sapiens]
(593 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens] 1221 0.0
gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens] 507 e-143
gi|114205383 secretin receptor precursor [Homo sapiens] 319 5e-87
gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens] 305 1e-82
gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens] 285 6e-77
gi|29171759 adenylate cyclase activating polypeptide 1 (pituitar... 278 1e-74
gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens] 266 5e-71
gi|4758438 glucagon-like peptide 2 receptor precursor [Homo sapi... 262 7e-70
gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens] 260 2e-69
gi|58530851 growth hormone releasing hormone receptor isoform a ... 249 5e-66
gi|4503947 glucagon receptor [Homo sapiens] 240 2e-63
gi|4502547 calcitonin receptor [Homo sapiens] 237 3e-62
gi|5031621 calcitonin receptor-like [Homo sapiens] 227 2e-59
gi|19923245 corticotropin releasing hormone receptor 1 isoform 2... 214 1e-55
gi|32307159 corticotropin releasing hormone receptor 2 [Homo sap... 214 2e-55
gi|223717971 corticotropin releasing hormone receptor 1 isoform ... 199 6e-51
gi|223717978 corticotropin releasing hormone receptor 1 isoform ... 193 3e-49
gi|58530853 growth hormone releasing hormone receptor isoform b ... 186 7e-47
gi|223717985 corticotropin releasing hormone receptor 1 isoform ... 184 2e-46
gi|45433552 G protein-coupled receptor 133 [Homo sapiens] 89 1e-17
gi|40807489 egf-like module containing, mucin-like, hormone rece... 74 3e-13
gi|133930786 egf-like module-containing mucin-like receptor 3 [H... 72 1e-12
gi|61743940 G-protein coupled receptor 110 isoform 1 [Homo sapiens] 68 2e-11
gi|163792198 latrophilin 3 precursor [Homo sapiens] 67 4e-11
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s... 65 1e-10
gi|59710093 G-protein coupled receptor 112 [Homo sapiens] 65 2e-10
gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens] 63 7e-10
gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens] 63 7e-10
gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens] 63 7e-10
gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens] 63 7e-10
>gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]
Length = 593
Score = 1221 bits (3159), Expect = 0.0
Identities = 593/593 (100%), Positives = 593/593 (100%)
Query: 1 MGTARIAPGLALLLCCPVLSSAYALVDADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPA 60
MGTARIAPGLALLLCCPVLSSAYALVDADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPA
Sbjct: 1 MGTARIAPGLALLLCCPVLSSAYALVDADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPA 60
Query: 61 SIMESDKGWTSASTSGKPRKDKASGKLYPESEEDKEAPTGSRYRGRPCLPEWDHILCWPL 120
SIMESDKGWTSASTSGKPRKDKASGKLYPESEEDKEAPTGSRYRGRPCLPEWDHILCWPL
Sbjct: 61 SIMESDKGWTSASTSGKPRKDKASGKLYPESEEDKEAPTGSRYRGRPCLPEWDHILCWPL 120
Query: 121 GAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETRE 180
GAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETRE
Sbjct: 121 GAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETRE 180
Query: 181 REVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVK 240
REVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVK
Sbjct: 181 REVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVK 240
Query: 241 DAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWIL 300
DAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWIL
Sbjct: 241 DAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWIL 300
Query: 301 VEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKK 360
VEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKK
Sbjct: 301 VEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKK 360
Query: 361 WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVH 420
WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVH
Sbjct: 361 WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVH 420
Query: 421 YIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLA 480
YIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLA
Sbjct: 421 YIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLA 480
Query: 481 LDFKRKARSGSSSYSYGPMVSHTSVTNVGPRVGLGLPLSPRLLPTATTNGHPQLPGHAKP 540
LDFKRKARSGSSSYSYGPMVSHTSVTNVGPRVGLGLPLSPRLLPTATTNGHPQLPGHAKP
Sbjct: 481 LDFKRKARSGSSSYSYGPMVSHTSVTNVGPRVGLGLPLSPRLLPTATTNGHPQLPGHAKP 540
Query: 541 GTPALETLETTPPAMAAPKDDGFLNGSCSGLDEEASGPERPPALLQEEWETVM 593
GTPALETLETTPPAMAAPKDDGFLNGSCSGLDEEASGPERPPALLQEEWETVM
Sbjct: 541 GTPALETLETTPPAMAAPKDDGFLNGSCSGLDEEASGPERPPALLQEEWETVM 593
>gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]
Length = 550
Score = 507 bits (1306), Expect = e-143
Identities = 256/477 (53%), Positives = 323/477 (67%), Gaps = 60/477 (12%)
Query: 22 AYALVDADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPASIMESDKGWTSASTSGKPRKD 81
A A +D+D +T EEQI L+ +A+ QCE + LQ
Sbjct: 22 ARAQLDSDGTITIEEQIVLVLKAKVQCELNITAQLQ------------------------ 57
Query: 82 KASGKLYPESEEDKEAPTGSRYRGRPCLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHK 141
E E + C PEWD ++CWP G G++ AVPCP YIYDFNHK
Sbjct: 58 --------EGEGN-------------CFPEWDGLICWPRGTVGKISAVPCPPYIYDFNHK 96
Query: 142 GHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETR--EREVFDRLGMIYTVGYSVSL 199
G A+R C+ NG+W+ + N+TWANYS+C++FL + ++E F+RL ++YTVGYS+S
Sbjct: 97 GVAFRHCNPNGTWDFMHSLNKTWANYSDCLRFLQPDISIGKQEFFERLYVMYTVGYSISF 156
Query: 200 ASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEE 259
SL VA+LI+ YFRRLHCTRNYIHMHLF+SFMLRA SIFVKD V+++ + E E L
Sbjct: 157 GSLAVAILIIGYFRRLHCTRNYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESL--- 213
Query: 260 ELRAIAQAPPPPATAAAG-----YAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAF 314
I Q P + A Y GC++AV F+YFLATNYYWILVEGLYLH+LIF+AF
Sbjct: 214 ----IMQDDPQNSIEATSVDKSQYIGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVAF 269
Query: 315 FSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKKWIIQVPILASIVLN 374
FS+ KYLWGF + GWG PA FVA W RATLA+ CW+LS+G+ KWI Q PILA+I LN
Sbjct: 270 FSDTKYLWGFILIGWGFPAAFVAAWAVARATLADARCWELSAGDIKWIYQAPILAAIGLN 329
Query: 375 FILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSG 434
FILF+N VRVLATK+ ETNA DTR+QYRKL KSTLVL+ +FGVHYIVF+ P++ +G
Sbjct: 330 FILFLNTVRVLATKIWETNAVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHS-FTG 388
Query: 435 TLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKARSGS 491
W+++MH E+ FNSFQGFFV+IIYC+CNGEVQAE+KK WSRW L++D+KR GS
Sbjct: 389 LGWEIRMHCELFFNSFQGFFVSIIYCYCNGEVQAEVKKMWSRWNLSVDWKRTPPCGS 445
>gi|114205383 secretin receptor precursor [Homo sapiens]
Length = 440
Score = 319 bits (817), Expect = 5e-87
Identities = 168/374 (44%), Positives = 232/374 (62%), Gaps = 33/374 (8%)
Query: 108 CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHK-GHAYRRCDRNGSWELVPGHNRTWAN 166
C WD+I CWP PG +V V CP ++ + G +R C ++G E P N
Sbjct: 66 CEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDGWSETFPRPNLACGV 125
Query: 167 YSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHL 226
V +NE R + +L ++YTVGYS SL L VA+ IL FRRLHCTRNYIHMHL
Sbjct: 126 N---VNDSSNEKRHSYLL-KLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHL 181
Query: 227 FLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVT 286
F+SF+LRA+S F+KDAVL+S + + A AGC++ +
Sbjct: 182 FVSFILRALSNFIKDAVLFSSDDVTYCD---------------------AHRAGCKLVMV 220
Query: 287 FFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATL 346
F Y + NY W+LVEGLYLH+L+ ++FFSE+KYL GF FGWG PA+FVA+W R L
Sbjct: 221 LFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFL 280
Query: 347 ANTGCWDL-SSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRK 405
+ GCWD+ ++ + WII+ P++ SI++NFILFINI+R+L KLR T R + Y++
Sbjct: 281 EDVGCWDINANASIWWIIRGPVILSILINFILFINILRILMRKLR-TQETRGNEVSHYKR 339
Query: 406 LLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGE 465
L +STL+L+PLFG+HYIVF +P + ++Q+ +E+ SFQG VA++YCF NGE
Sbjct: 340 LARSTLLLIPLFGIHYIVFAFSPEDAM-----EIQLFFELALGSFQGLVVAVLYCFLNGE 394
Query: 466 VQAEIKKSWSRWTL 479
VQ E++K W +W L
Sbjct: 395 VQLEVQKKWQQWHL 408
>gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]
Length = 457
Score = 305 bits (780), Expect = 1e-82
Identities = 164/411 (39%), Positives = 235/411 (57%), Gaps = 35/411 (8%)
Query: 108 CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFN--HKGHAYRRCDRNGSWELVPGHNRTWA 165
C WD++ CWP G+VV + CP F+ + R C G L PG
Sbjct: 63 CSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIAC 122
Query: 166 NYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMH 225
+ K + + ++ + + YT+GY +SLA+L VA IL+ FR+LHCTRNYIHMH
Sbjct: 123 GLDD--KAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMH 180
Query: 226 LFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAV 285
LF+SF+LRA ++F+KD L+ D+ G GC+ A+
Sbjct: 181 LFISFILRAAAVFIKDLALFDSGESDQCSE---------------------GSVGCKAAM 219
Query: 286 TFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRAT 345
FF Y + N++W+LVEGLYL++L+ ++FFSE+KY WG+ + GWG+P+ F VW R
Sbjct: 220 VFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIH 279
Query: 346 LANTGCWDLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRK 405
+ GCWD + + WII+ PIL SI++NFILFI I+R+L KLR + + D+ Y +
Sbjct: 280 FEDYGCWDTINSSLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKSDS-SPYSR 338
Query: 406 LLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGE 465
L +STL+L+PLFGVHYI+F P +V+M +E++ SFQGF VAI+YCF NGE
Sbjct: 339 LARSTLLLIPLFGVHYIMFAFFP----DNFKPEVKMVFELVVGSFQGFVVAILYCFLNGE 394
Query: 466 VQAEIKKSWSRWTL--ALDFKRKAR---SGSSSYSYGPMVSHTSVTNVGPR 511
VQAE+++ W RW L L + K R GS+ + VS + + G R
Sbjct: 395 VQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCSTQVSMLTRVSPGAR 445
>gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]
Length = 438
Score = 285 bits (730), Expect = 6e-77
Identities = 156/393 (39%), Positives = 227/393 (57%), Gaps = 34/393 (8%)
Query: 106 RPCLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHK-GHAYRRCDRNGSWELVPGHNRTW 164
+ C WD+I CW GE V VPCP +F K G+ + C +G W + T+
Sbjct: 50 KACSGVWDNITCWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDG-W------SETF 102
Query: 165 ANYSECVKFLTNETREREVFDRL-GMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIH 223
++ + + E + F L IYT+GYSVSL SL +IL FR+LHCTRNYIH
Sbjct: 103 PDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIH 162
Query: 224 MHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRV 283
++LFLSF+LRA+S+ VKD VLYS + P P++ + GC++
Sbjct: 163 LNLFLSFILRAISVLVKDDVLYSSS--------------GTLHCPDQPSS----WVGCKL 204
Query: 284 AVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVR 343
++ F Y + N++W+LVEGLYLH+L+ +A ++ + + GWGLP V + W + R
Sbjct: 205 SLVFLQYCIMANFFWLLVEGLYLHTLL-VAMLPPRRCFLAYLLIGWGLPTVCIGAWTAAR 263
Query: 344 ATLANTGCWDLSSGNKK-WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQ 402
L +TGCWD + + W+I++PIL SI++NF+LFI+I+R+L KL + G D + Q
Sbjct: 264 LYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGND-QSQ 322
Query: 403 YRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFC 462
Y++L KSTL+L+PLFGVHY+VF P + S + Q+ +E+ SFQG VA++YCF
Sbjct: 323 YKRLAKSTLLLIPLFGVHYMVFAVFPISISS----KYQILFELCLGSFQGLVVAVLYCFL 378
Query: 463 NGEVQAEIKKSWSRWTLALDFKRKARSGSSSYS 495
N EVQ E+K+ W R R SS+S
Sbjct: 379 NSEVQCELKRKWRSRCPTPSASRDYRVCGSSFS 411
>gi|29171759 adenylate cyclase activating polypeptide 1 (pituitary)
receptor type I precursor [Homo sapiens]
Length = 468
Score = 278 bits (711), Expect = 1e-74
Identities = 162/443 (36%), Positives = 242/443 (54%), Gaps = 67/443 (15%)
Query: 108 CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFN------------------------HKGH 143
C WD+I CW GE+V V CP+ FN G
Sbjct: 54 CPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGV 113
Query: 144 AYRRCDRNGSWELVPGHNRTWANYSECVKF--LTNETREREVFD-RLGMIYTVGYSVSLA 200
R C +G E P +Y + F +ET +++ + + +YTVGYS SL
Sbjct: 114 VSRNCTEDGWSEPFP-------HYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLV 166
Query: 201 SLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEE 260
+LT A++IL FR+LHCTRN+IHM+LF+SFMLRA+S+F+KD +LY+ + T E
Sbjct: 167 TLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVE- 225
Query: 261 LRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKY 320
C+ + FF Y + +NY+W+ +EGLYL +L+ FF E++Y
Sbjct: 226 --------------------CKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRY 265
Query: 321 LWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKK-WIIQVPILASIVLNFILFI 379
+ +T+ GWG P V V VW ++R +TGCWD++ W+I+ P++ SI++NF+LFI
Sbjct: 266 FYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFI 325
Query: 380 NIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQV 439
I+ +L KL+ + G ++ Y +L +STL+L+PLFG+HY VF +P +
Sbjct: 326 GIIVILVQKLQSPDMGGNES-SIYLRLARSTLLLIPLFGIHYTVFAFSP----ENVSKRE 380
Query: 440 QMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTL----ALDFKRKARS-GSSSY 494
++ +E+ SFQGF VA++YCF NGEVQAEIK+ W W + A+DFK + S SS
Sbjct: 381 RLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGV 440
Query: 495 SYGPMVSHTSVTNVGPRVGLGLP 517
+ G +S S ++ R+ GLP
Sbjct: 441 NGGTQLSILSKSSSQIRMS-GLP 462
>gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]
Length = 466
Score = 266 bits (679), Expect = 5e-71
Identities = 157/410 (38%), Positives = 226/410 (55%), Gaps = 45/410 (10%)
Query: 80 KDKASGKLYPESEEDKEAPTGSRYRGRP-----CLPEWDHILCWPLGAPGEVVAVPCPDY 134
K + +G+LY E + + P C +D +CW AP CP Y
Sbjct: 28 KGQTAGELYQRWERYRRECQETLAAAEPPSGLACNGSFDMYVCWDYAAPNATARASCPWY 87
Query: 135 IYDFNH--KGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNET--REREVFDRLGMI 190
+ +H G R+C +G W L W ++++C NE +R + +RL ++
Sbjct: 88 LPWHHHVAAGFVLRQCGSDGQWGL-------WRDHTQCENPEKNEAFLDQRLILERLQVM 140
Query: 191 YTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVL-----Y 245
YTVGYS+SLA+L +A+LIL+ FRRLHCTRNYIH++LF SFMLRA +I +D +L Y
Sbjct: 141 YTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPY 200
Query: 246 SGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLY 305
G D+A L + L A CR A Y + NY W+LVEG+Y
Sbjct: 201 LG---DQALALWNQAL-----------------AACRTAQIVTQYCVGANYTWLLVEGVY 240
Query: 306 LHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGNK-KWIIQ 364
LHSL+ + SE+ + + + GWG PA+FV WV VR NT CW+ + WII+
Sbjct: 241 LHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIR 300
Query: 365 VPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVF 424
PIL +I++NF++FI I+ +L +KLR T RC R +L +STL L+PL GVH +VF
Sbjct: 301 TPILMTILINFLIFIRILGILLSKLR-TRQMRC--RDYRLRLARSTLTLVPLLGVHEVVF 357
Query: 425 MATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSW 474
+ G L ++ +E+ +SFQGF V+++YCF N EVQ+EI++ W
Sbjct: 358 APVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGW 407
>gi|4758438 glucagon-like peptide 2 receptor precursor [Homo
sapiens]
Length = 553
Score = 262 bits (669), Expect = 7e-70
Identities = 148/381 (38%), Positives = 216/381 (56%), Gaps = 27/381 (7%)
Query: 108 CLPEWDHILCWPLGAPGEVVAVPCPDYI--YDFNHKGHAYRRCDRNGSWELVPGHNRTWA 165
C +D +CWP +PG V +VPCP Y+ + G AYR C G+W+ + W
Sbjct: 96 CNGTFDQYVCWPHSSPGNV-SVPCPSYLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQ 154
Query: 166 NYSECVK---FLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYI 222
+ SEC + F N R + L ++YTVGYS SL SL +A+ +L + R+LHCTRNYI
Sbjct: 155 DDSECSENHSFKQNVDRYA-LLSTLQLMYTVGYSFSLISLFLALTLLLFLRKLHCTRNYI 213
Query: 223 HMHLFLSFMLRAVSIFVKDAVLYSG-ATLDEAERLTEEELRAIAQAPPPPATAAAGYAGC 281
HM+LF SF+LR +++ VKD V Y+ + + E L ++ + C
Sbjct: 214 HMNLFASFILRTLAVLVKDVVFYNSYSKRPDNENGWMSYLSEMSTS-------------C 260
Query: 282 RVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVS 341
R YF+ NY W+LVEGLYLH+L+ E++ + + GW P +FV W
Sbjct: 261 RSVQVLLHYFVGANYLWLLVEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPVLFVVPWGF 320
Query: 342 VRATLANTGCWDLSSGNKK--WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDT 399
RA L NTGCW ++GNKK WII+ P++ + +NF +F+ I+++L +KL+ C
Sbjct: 321 ARAHLENTGCW-TTNGNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQ--MCFR 377
Query: 400 RQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIY 459
+YR L KSTLVL+PL GVH I+F +V G +++ ++ +SF GF VA+ Y
Sbjct: 378 DYKYR-LAKSTLVLIPLLGVHEILFSFITDDQVEGFAKLIRLFIQLTLSSFHGFLVALQY 436
Query: 460 CFCNGEVQAEIKKSWSRWTLA 480
F NGEV+AE++K W R+ LA
Sbjct: 437 GFANGEVKAELRKYWVRFLLA 457
>gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]
Length = 463
Score = 260 bits (665), Expect = 2e-69
Identities = 146/379 (38%), Positives = 211/379 (55%), Gaps = 25/379 (6%)
Query: 108 CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNH--KGHAYRRCDRNGSWELVPGHNRTWA 165
C +D CWP G PG V V CP Y+ + +GH YR C G W + W
Sbjct: 62 CNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWR 121
Query: 166 NYSECVKFLTNE-TREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHM 224
+ SEC + E + E L +IYTVGY++S ++L +A IL FR LHCTRNYIH+
Sbjct: 122 DLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHL 181
Query: 225 HLFLSFMLRAVSIFVKDAVL---YSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGC 281
+LF SF+LRA+S+F+KDA L YS A A++ + L + + C
Sbjct: 182 NLFASFILRALSVFIKDAALKWMYSTA----AQQHQWDGLLSYQDS-----------LSC 226
Query: 282 RVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVS 341
R+ Y +A NYYW+LVEG+YL++L+ + SE+ + GWG+P +FV W
Sbjct: 227 RLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGI 286
Query: 342 VRATLANTGCWDLSSGNKKW-IIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTR 400
V+ + GCW +S W II++PIL +I +NF++F+ ++ ++ +KL+ + D +
Sbjct: 287 VKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIK 346
Query: 401 QQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYC 460
+L KSTL L+PL G H ++F GTL +++ E+ F SFQG VAI+YC
Sbjct: 347 C---RLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYC 403
Query: 461 FCNGEVQAEIKKSWSRWTL 479
F N EVQ E +KSW RW L
Sbjct: 404 FVNNEVQLEFRKSWERWRL 422
>gi|58530851 growth hormone releasing hormone receptor isoform a
precursor [Homo sapiens]
Length = 423
Score = 249 bits (636), Expect = 5e-66
Identities = 139/369 (37%), Positives = 195/369 (52%), Gaps = 34/369 (9%)
Query: 108 CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRR-CDRNGSWELVPGHNRTWAN 166
C WD +LCWP GE V +PCPD+ F+ + A +R C G E P +
Sbjct: 55 CPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVA--- 111
Query: 167 YSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHL 226
C L E F + +IYTVG+S+S+ +L VA+ IL RRLHC RNY+H L
Sbjct: 112 ---CPVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQL 168
Query: 227 FLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVT 286
F +F+L+A ++F+KDA L+ D T C+V+V
Sbjct: 169 FTTFILKAGAVFLKDAALFHSDDTDHCSFST---------------------VLCKVSVA 207
Query: 287 FFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATL 346
+ TN+ W+L E +YL+ L+ S ++ W + GWGLP +F WVS +
Sbjct: 208 ASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAF 267
Query: 347 ANTGCWDLSSGNKK-WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRK 405
+ CWDL + WII+ PI+ S+ +NF LF+NI+R+L KL E G T+ QY +
Sbjct: 268 EDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKL-EPAQGSLHTQSQYWR 326
Query: 406 LLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGE 465
L KSTL L+PLFG+HYI+F P G +++ E+ SFQGF VAI+YCF N E
Sbjct: 327 LSKSTLFLIPLFGIHYIIFNFLPDNAGLG----IRLPLELGLGSFQGFIVAILYCFLNQE 382
Query: 466 VQAEIKKSW 474
V+ EI + W
Sbjct: 383 VRTEISRKW 391
>gi|4503947 glucagon receptor [Homo sapiens]
Length = 477
Score = 240 bits (613), Expect = 2e-63
Identities = 143/406 (35%), Positives = 210/406 (51%), Gaps = 35/406 (8%)
Query: 108 CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGH---AYRRCDRNGSWELVPGHNRTW 164
C +D CWP + CP Y+ ++HK ++RC +G W P + W
Sbjct: 58 CNRTFDKYSCWPDTPANTTANISCPWYL-PWHHKVQHRFVFKRCGPDGQWVRGP-RGQPW 115
Query: 165 ANYSECVKFLTNETREREV---FDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNY 221
+ S+C ++EV + ++YTVGYS+SL +L +A+ IL +LHCTRN
Sbjct: 116 RDASQCQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNA 175
Query: 222 IHMHLFLSFMLRAVSIFVKDAVL---YSGATLDEAERLTEEELRAIAQAPPPPATAAAGY 278
IH +LF SF+L+A S+ V D +L YS D+ T A+A
Sbjct: 176 IHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVA------------- 222
Query: 279 AGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAV 338
GCRVA F Y + NY W+LVEGLYLH+L+ +A E+ + + GWG P +FV
Sbjct: 223 -GCRVAAVFMQYGIVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVP 281
Query: 339 WVSVRATLANTGCWDLSSGNKK--WIIQVPILASIVLNFILFINIVRVLATKLRETNAGR 396
W V+ N CW S+ N WI++ P+ +I++NF +F+ IV++L KLR
Sbjct: 282 WAVVKCLFENVQCWT-SNDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHH 340
Query: 397 CDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVA 456
D + +L KSTL L+PL GVH +VF GTL ++ +++ +SFQG VA
Sbjct: 341 TDYKF---RLAKSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVA 397
Query: 457 IIYCFCNGEVQAEIKKSWSRWTLAL----DFKRKARSGSSSYSYGP 498
++YCF N EVQ+E+++ W RW L + SSS +GP
Sbjct: 398 VLYCFLNKEVQSELRRRWHRWRLGKVLWEERNTSNHRASSSPGHGP 443
>gi|4502547 calcitonin receptor [Homo sapiens]
Length = 474
Score = 237 bits (604), Expect = 3e-62
Identities = 126/375 (33%), Positives = 196/375 (52%), Gaps = 32/375 (8%)
Query: 105 GRPCLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTW 164
G C WD LCW G + CPDY DF+ + CD G W P +NRTW
Sbjct: 69 GPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFKHPENNRTW 128
Query: 165 ANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHM 224
+NY+ C F + + V L + VG+S+S+ +L +++ I +FR L C R +H
Sbjct: 129 SNYTMCNAFTPEKLKNAYVLYYLAI---VGHSLSIFTLVISLGIFVFFRSLGCQRVTLHK 185
Query: 225 HLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVA 284
++FL+++L ++ I + + + P C++
Sbjct: 186 NMFLTYILNSMIIIIH-----------------------LVEVVPNGELVRRDPVSCKIL 222
Query: 285 VTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRA 344
F Y +A NY+W+L EG+YLH+LI +A F+EK+ L + + GWG P V + RA
Sbjct: 223 HFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRA 282
Query: 345 TLANTGCWDLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYR 404
N CW + +II P++A++V+NF +NIVRVL TK+RET+ Y
Sbjct: 283 VYFNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAE---SHMYL 339
Query: 405 KLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNG 464
K +K+T++L+PL G+ ++VF P ++ G ++ MH + FQGFFVA IYCFCN
Sbjct: 340 KAVKATMILVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLI---HFQGFFVATIYCFCNN 396
Query: 465 EVQAEIKKSWSRWTL 479
EVQ +K+ W+++ +
Sbjct: 397 EVQTTVKRQWAQFKI 411
>gi|5031621 calcitonin receptor-like [Homo sapiens]
Length = 461
Score = 227 bits (579), Expect = 2e-59
Identities = 132/404 (32%), Positives = 205/404 (50%), Gaps = 43/404 (10%)
Query: 108 CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANY 167
C WD LCW A G CPDY DF+ + CD++G+W P NRTW NY
Sbjct: 65 CNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRTWTNY 124
Query: 168 SECVKFLTNETREREVFDRLGMIYT--VGYSVSLASLTVAVLILAYFRRLHCTRNYIHMH 225
++C N +V L + Y +G+ +S+ASL +++ I YF+ L C R +H +
Sbjct: 125 TQC-----NVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKN 179
Query: 226 LFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAV 285
LF SF+ +V + L A+A A A C+V+
Sbjct: 180 LFFSFVCNSVVTII--------------------HLTAVANNQ---ALVATNPVSCKVSQ 216
Query: 286 TFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRAT 345
LY + NY+W+L EG+YLH+LI +A F+EK++L + GWG P + + R+
Sbjct: 217 FIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSL 276
Query: 346 LANTGCWDLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRK 405
N CW S + +II PI A++++N +NIVRVL TKL+ T+ + Y K
Sbjct: 277 YYNDNCWISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNL---YMK 333
Query: 406 LLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGE 465
+++TL+L+PL G+ +++ P +++ ++ MH M FQG V+ I+CF NGE
Sbjct: 334 AVRATLILVPLLGIEFVLIPWRPEGKIAEEVYDYIMHILM---HFQGLLVSTIFCFFNGE 390
Query: 466 VQAEIKKSWSRWTLAL--DFKRKARSGSSSY-----SYGPMVSH 502
VQA ++++W+++ + F S+SY S GP SH
Sbjct: 391 VQAILRRNWNQYKIQFGNSFSNSEALRSASYTVSTISDGPGYSH 434
>gi|19923245 corticotropin releasing hormone receptor 1 isoform 2
[Homo sapiens]
Length = 415
Score = 214 bits (546), Expect = 1e-55
Identities = 125/383 (32%), Positives = 184/383 (48%), Gaps = 44/383 (11%)
Query: 101 SRYRGRPCLPEWDHI-LCWPLGAPGEVVAVPCPDYIYD--FNHKGHAYRRCDRNGSWELV 157
S G C D I CWP G++V PCP + Y +N + YR C NGSW
Sbjct: 37 SNISGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWA-- 94
Query: 158 PGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHC 217
NYSEC + L E + + + +I +G+ +SL +L VA ++ R + C
Sbjct: 95 -----ARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRC 149
Query: 218 TRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAG 277
RN IH +L +F+LR + FV Q P +
Sbjct: 150 LRNIIHWNLISAFILRNATWFV-------------------------VQLTMSPEVHQSN 184
Query: 278 YAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVA 337
CR+ + YF TN++W+ EG YLH+ I + + +++ W F GWG+P +
Sbjct: 185 VGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIV 244
Query: 338 VWVSVRATLANTGCW--DLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAG 395
W + N CW +I Q P++ +++NFI NIVR+L TKLR A
Sbjct: 245 AWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLR---AS 301
Query: 396 RCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATP-YTEVSGTLWQVQMHYEMLFNSFQGFF 454
QYRK +K+TLVL+PL G+ Y++F P EVS ++ +++ SFQGFF
Sbjct: 302 TTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVF---IYFNSFLESFQGFF 358
Query: 455 VAIIYCFCNGEVQAEIKKSWSRW 477
V++ YCF N EV++ I+K W RW
Sbjct: 359 VSVFYCFLNSEVRSAIRKRWHRW 381
>gi|32307159 corticotropin releasing hormone receptor 2 [Homo
sapiens]
Length = 411
Score = 214 bits (545), Expect = 2e-55
Identities = 124/367 (33%), Positives = 189/367 (51%), Gaps = 45/367 (12%)
Query: 117 CWPLGAPGEVVAVPCPDYI--YDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFL 174
CWP A G +V PCP+Y +N +AYR C NG+W + NYS+C L
Sbjct: 50 CWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGTWA-------SKINYSQCEPIL 102
Query: 175 TNETREREVFDRLGMIYT-VGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLR 233
++ R+ ++ R+ ++ +G+ VS+A+L A L+ R + C RN IH +L +F+LR
Sbjct: 103 DDKQRKYDLHYRIALVVNYLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILR 162
Query: 234 AVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLA 293
V F+ +L + E+ + CR T F YF+
Sbjct: 163 NVMWFLL--------------QLVDHEVH------------ESNEVWCRCITTIFNYFVV 196
Query: 294 TNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLANTGCW- 352
TN++W+ VEG YLH+ I M + +E+ F GW +P + W + N CW
Sbjct: 197 TNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQCWF 256
Query: 353 DLSSGN-KKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTL 411
G+ +I Q PI+ +++NF+ NIVR+L TKLR A QYRK +K+TL
Sbjct: 257 GKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLR---ASTTSETIQYRKAVKATL 313
Query: 412 VLMPLFGVHYIVFMATPYTEVSGTLWQVQ-MHYEMLFNSFQGFFVAIIYCFCNGEVQAEI 470
VL+PL G+ Y++F P + L Q+ +++ SFQGFFV++ YCF NGEV++ +
Sbjct: 314 VLLPLLGITYMLFFVNPGED---DLSQIMFIYFNSFLQSFQGFFVSVFYCFFNGEVRSAV 370
Query: 471 KKSWSRW 477
+K W RW
Sbjct: 371 RKRWHRW 377
>gi|223717971 corticotropin releasing hormone receptor 1 isoform 1
[Homo sapiens]
Length = 444
Score = 199 bits (506), Expect = 6e-51
Identities = 125/412 (30%), Positives = 184/412 (44%), Gaps = 73/412 (17%)
Query: 101 SRYRGRPCLPEWDHI-LCWPLGAPGEVVAVPCPDYIYD--FNHKGHAYRRCDRNGSWELV 157
S G C D I CWP G++V PCP + Y +N + YR C NGSW
Sbjct: 37 SNISGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWA-- 94
Query: 158 PGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFR---- 213
NYSEC + L E + + + +I +G+ +SL +L VA ++ R
Sbjct: 95 -----ARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRPGCT 149
Query: 214 -------------------------RLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGA 248
+ C RN IH +L +F+LR + FV
Sbjct: 150 HWGDQADGALEVGAPWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFV--------- 200
Query: 249 TLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHS 308
Q P + CR+ + YF TN++W+ EG YLH+
Sbjct: 201 ----------------VQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHT 244
Query: 309 LIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLANTGCW--DLSSGNKKWIIQVP 366
I + + +++ W F GWG+P + W + N CW +I Q P
Sbjct: 245 AIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGP 304
Query: 367 ILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMA 426
++ +++NFI NIVR+L TKLR A QYRK +K+TLVL+PL G+ Y++F
Sbjct: 305 MILVLLINFIFLFNIVRILMTKLR---ASTTSETIQYRKAVKATLVLLPLLGITYMLFFV 361
Query: 427 TP-YTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRW 477
P EVS ++ +++ SFQGFFV++ YCF N EV++ I+K W RW
Sbjct: 362 NPGEDEVSRVVF---IYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRW 410
>gi|223717978 corticotropin releasing hormone receptor 1 isoform 3
[Homo sapiens]
Length = 375
Score = 193 bits (491), Expect = 3e-49
Identities = 111/342 (32%), Positives = 166/342 (48%), Gaps = 41/342 (11%)
Query: 139 NHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVS 198
N + YR C NGSW NYSEC + L E + + + +I +G+ +S
Sbjct: 38 NISDNGYRECLANGSWA-------ARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCIS 90
Query: 199 LASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTE 258
L +L VA ++ R + C RN IH +L +F+LR + FV
Sbjct: 91 LVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFV------------------- 131
Query: 259 EELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEK 318
Q P + CR+ + YF TN++W+ EG YLH+ I + + +++
Sbjct: 132 ------VQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDR 185
Query: 319 KYLWGFTVFGWGLPAVFVAVWVSVRATLANTGCW--DLSSGNKKWIIQVPILASIVLNFI 376
W F GWG+P + W + N CW +I Q P++ +++NFI
Sbjct: 186 LRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFI 245
Query: 377 LFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATP-YTEVSGT 435
NIVR+L TKLR A QYRK +K+TLVL+PL G+ Y++F P EVS
Sbjct: 246 FLFNIVRILMTKLR---ASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRV 302
Query: 436 LWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRW 477
++ +++ SFQGFFV++ YCF N EV++ I+K W RW
Sbjct: 303 VF---IYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRW 341
>gi|58530853 growth hormone releasing hormone receptor isoform b
precursor [Homo sapiens]
Length = 337
Score = 186 bits (471), Expect = 7e-47
Identities = 105/298 (35%), Positives = 150/298 (50%), Gaps = 30/298 (10%)
Query: 108 CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRR-CDRNGSWELVPGHNRTWAN 166
C WD +LCWP GE V +PCPD+ F+ + A +R C G E P +
Sbjct: 55 CPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVA--- 111
Query: 167 YSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHL 226
C L E F + +IYTVG+S+S+ +L VA+ IL RRLHC RNY+H L
Sbjct: 112 ---CPVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQL 168
Query: 227 FLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVT 286
F +F+L+A ++F+KDA L+ D T C+V+V
Sbjct: 169 FTTFILKAGAVFLKDAALFHSDDTDHCSFST---------------------VLCKVSVA 207
Query: 287 FFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATL 346
+ TN+ W+L E +YL+ L+ S ++ W + GWGLP +F WVS +
Sbjct: 208 ASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAF 267
Query: 347 ANTGCWDLSSGNKK-WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQY 403
+ CWDL + WII+ PI+ S+ +NF LF+NI+R+L KL E G T+ QY
Sbjct: 268 EDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKL-EPAQGSLHTQSQY 324
>gi|223717985 corticotropin releasing hormone receptor 1 isoform 4
[Homo sapiens]
Length = 401
Score = 184 bits (467), Expect = 2e-46
Identities = 118/383 (30%), Positives = 174/383 (45%), Gaps = 58/383 (15%)
Query: 101 SRYRGRPCLPEWDHI-LCWPLGAPGEVVAVPCPDYIYD--FNHKGHAYRRCDRNGSWELV 157
S G C D I CWP G++V PCP + Y +N + YR C NGSW
Sbjct: 37 SNISGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWA-- 94
Query: 158 PGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHC 217
NYSEC + L E + + + +I +G+ +SL +L VA ++ R + C
Sbjct: 95 -----ARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRC 149
Query: 218 TRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAG 277
RN IH +L +F+LR + FV Q P +
Sbjct: 150 LRNIIHWNLISAFILRNATWFV-------------------------VQLTMSPEVHQSN 184
Query: 278 YAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVA 337
CR+ + YF TN++W+ EG YLH+ I + + +++ W F GWG+P +
Sbjct: 185 VGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIV 244
Query: 338 VWVSVRATLANTGCW--DLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAG 395
W + N CW +I Q P++ +++NFI NIVR+L TKLR A
Sbjct: 245 AWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLR---AS 301
Query: 396 RCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATP-YTEVSGTLWQVQMHYEMLFNSFQGFF 454
QYRK +K+TLVL+PL G+ Y++F P EVS ++ + FNSF F
Sbjct: 302 TTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVF-------IYFNSFLESF 354
Query: 455 VAIIYCFCNGEVQAEIKKSWSRW 477
+V++ I+K W RW
Sbjct: 355 ----------QVRSAIRKRWHRW 367
>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
Length = 874
Score = 89.0 bits (219), Expect = 1e-17
Identities = 80/309 (25%), Positives = 126/309 (40%), Gaps = 44/309 (14%)
Query: 187 LGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNY-IHMHLFLSFMLRAVSIFVKDAVLY 245
L I VG S+S+ L ++ A + RN H+H LSF AVL
Sbjct: 566 LSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSF-----------AVLV 614
Query: 246 SGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLY 305
+ L + RL G C+V YF + + W+LVEGL+
Sbjct: 615 AQVLLLISFRLEP------------------GTTPCQVMAVLLHYFFLSAFAWMLVEGLH 656
Query: 306 LHSLIFMAFFSE---KKYLWGFTVFGWGLPAVFVAVWVSVRATLANT--GCWDLSSGNKK 360
L+S++ F SE +Y +G GWG P + + +S T CW +
Sbjct: 657 LYSMVIKVFGSEDSKHRYYYG---MGWGFPLLICIISLSFAMDSYGTSNNCWLSLASGAI 713
Query: 361 WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVH 420
W P L IV+N + I + RV+ +++ N ++ K+ VL+P+ G
Sbjct: 714 WAFVAPALFVIVVNIGILIAVTRVI-SQISADNYKIHGDPSAFKLTAKAVAVLLPILGTS 772
Query: 421 YIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLA 480
++ + V+G Q + L NS QG F+ + +C N EV+A K W+L
Sbjct: 773 WVFGVLA----VNGCAVVFQYMFATL-NSLQGLFIFLFHCLLNSEVRAAFKHKTKVWSLT 827
Query: 481 LDFKRKARS 489
R + +
Sbjct: 828 SSSARTSNA 836
>gi|40807489 egf-like module containing, mucin-like, hormone
receptor-like sequence 1 [Homo sapiens]
Length = 886
Score = 74.3 bits (181), Expect = 3e-13
Identities = 68/295 (23%), Positives = 120/295 (40%), Gaps = 48/295 (16%)
Query: 187 LGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYS 246
L +I VG +SL L +A+ R + Y+H+HL + +L A ++F+
Sbjct: 602 LYIISHVGIIISLVCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLL-AKTLFLAGI---- 656
Query: 247 GATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYL 306
T+ ++ GC + F Y ++W+LVE + L
Sbjct: 657 --------HKTDNKM------------------GCAIIAGFLHYLFLACFFWMLVEAVIL 690
Query: 307 HSLI----FMAFFSEKKY-LWGFTVFGWGLPAVFVAVWVSVRATL--ANTGCWDLSSGNK 359
++ + +FS + + FG+GLP + V + SV+ + CW +
Sbjct: 691 FLMVRNLKVVNYFSSRNIKMLHICAFGYGLPMLVVVISASVQPQGYGMHNRCWLNTETGF 750
Query: 360 KWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGV 419
W P+ IV+N +L + +L +L NA T + R L + + G
Sbjct: 751 IWSFLGPVCTVIVINSLLLTWTLWILRQRLSSVNA-EVSTLKDTRLLTFKAFAQLFILGC 809
Query: 420 HYI--VFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKK 472
++ +F P V L+ + NS QG F+ +I+C NG+V+ E K+
Sbjct: 810 SWVLGIFQIGPVAGVMAYLFTI-------INSLQGAFIFLIHCLLNGQVREEYKR 857
>gi|133930786 egf-like module-containing mucin-like receptor 3 [Homo
sapiens]
Length = 652
Score = 72.4 bits (176), Expect = 1e-12
Identities = 87/355 (24%), Positives = 139/355 (39%), Gaps = 54/355 (15%)
Query: 150 RNGSWELVPGHNRTWANYSECVKF-LTNETREREVFDRLGMIYTVGYSVSLASLTVAVLI 208
R+G + + + T N S F + +E L +I VG SVSL L +A L
Sbjct: 318 RDGCFLIHVNKSHTMCNCSHLSSFAVLMALTSQEEDPVLTVITYVGLSVSLLCLLLAALT 377
Query: 209 LAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAP 268
+ + T +H+ L L L + V +D E
Sbjct: 378 FLLCKAIRNTSTSLHLQLSLCLFLAHLLFLVG---------IDRTE-------------- 414
Query: 269 PPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYL----HSLIFMAFFSEKKYL-WG 323
P + AG +LY A + W+L+EG++L +L + + S + + W
Sbjct: 415 --PKVLCSIIAGA----LHYLYLAA--FTWMLLEGVHLFLTARNLTVVNYSSINRLMKWI 466
Query: 324 FTVFGWGLPAVFVAVWVSVRATLANTG--CWDLSSGNKKWIIQVPILASIVLNFILFINI 381
G+G+PAV VA+ + L T CW W P+ A N +LFI +
Sbjct: 467 MFPVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSANLVLFILV 526
Query: 382 VRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQM 441
+L KL N+ T Q R L + + G + + + G QV
Sbjct: 527 FWILKRKLSSLNS-EVSTIQNTRMLAFKATAQLFILGCTWCLGLLQV-----GPAAQVMA 580
Query: 442 HYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKARSGSSSYSY 496
+ + NS QGFF+ ++YC + +VQ K + +W F+ +S S S +Y
Sbjct: 581 YLFTIINSLQGFFIFLVYCLLSQQVQ----KQYQKW-----FREIVKSKSESETY 626
>gi|61743940 G-protein coupled receptor 110 isoform 1 [Homo sapiens]
Length = 910
Score = 68.2 bits (165), Expect = 2e-11
Identities = 79/332 (23%), Positives = 141/332 (42%), Gaps = 48/332 (14%)
Query: 183 VFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDA 242
+F + I VG +S+ SL + ++I A F + H + A+S+ + D
Sbjct: 581 IFPVVKWITYVGLGISIGSLILCLIIEALFWKQIKKSQTSHTRRICMVNI-ALSLLIADV 639
Query: 243 VLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVE 302
GAT+D T C AV F +F + ++W+L+
Sbjct: 640 WFIVGATVD---------------------TTVNPSGVCTAAVFFTHFFYLSLFFWMLML 678
Query: 303 GLYLHSLIFMAFFSEKKYLW---GFTVFGWGLPAVFVAVWVSVRATLANTG-----CW-D 353
G+ L I + F ++L GF + G+G P + + ++V +NT CW +
Sbjct: 679 GILLAYRIILVFHHMAQHLMMAVGFCL-GYGCPLIISVITIAVTQP-SNTYKRKDVCWLN 736
Query: 354 LSSGNKKWI-IQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLL---KS 409
S+G+K + VP LA + +NF+ +V ++ TKL G +R ++ KS
Sbjct: 737 WSNGSKPLLAFVVPALAIVAVNFV----VVLLVLTKLWRPTVGERLSRDDKATIIRVGKS 792
Query: 410 TLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAE 469
L+L PL G+ + + T + W V L N+FQGFF+ + +++
Sbjct: 793 LLILTPLLGLTWGFGIGT-IVDSQNLAWHVIF---ALLNAFQGFFILCFGILLDSKLRQL 848
Query: 470 IKKSWSRWTLALDFKRKARSGSSSYSYGPMVS 501
+ +++ + +K+ + SS S P S
Sbjct: 849 L---FNKLSALSSWKQTEKQNSSDLSAKPKFS 877
>gi|163792198 latrophilin 3 precursor [Homo sapiens]
Length = 1469
Score = 67.4 bits (163), Expect = 4e-11
Identities = 77/307 (25%), Positives = 121/307 (39%), Gaps = 68/307 (22%)
Query: 187 LGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYS 246
L +I VG +SL L + + +FR L RN IH +L +S+FV + +
Sbjct: 877 LDVITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNL-------CISLFVAELLFLI 929
Query: 247 GATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYL 306
G I + P A C V +F + W+ +EG+ L
Sbjct: 930 G----------------INRTDQPIA--------CAVFAALLHFFFLAAFTWMFLEGVQL 965
Query: 307 HSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSV--RATLANTGCWDLSSGNKKWIIQ 364
+ ++ F SE F + G+G+PA+ VAV +V R+ + CW W
Sbjct: 966 YIMLVEVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFI 1025
Query: 365 VPILASIVLNFILFINIVRVLA---TKLRETNAGRCD--TRQQYRKLLKSTLV------- 412
P I+LN ++F+ I T + + +G D + R +KS ++
Sbjct: 1026 GPATLIIMLN-VIFLGIALYKMFHHTAILKPESGCLDNINYEDNRPFIKSWVIGAIALLC 1084
Query: 413 ---LMPLFGVHYI----VFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGE 465
L FG+ YI V MA +T +FNS QG F+ I +C +
Sbjct: 1085 LLGLTWAFGLMYINESTVIMAYLFT---------------IFNSLQGMFIFIFHCVLQKK 1129
Query: 466 VQAEIKK 472
V+ E K
Sbjct: 1130 VRKEYGK 1136
>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
sapiens]
Length = 3014
Score = 65.5 bits (158), Expect = 1e-10
Identities = 65/288 (22%), Positives = 114/288 (39%), Gaps = 45/288 (15%)
Query: 187 LGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYS 246
L ++ S+SLA+L VA ++L+ R L + IH HL AV++F+ V
Sbjct: 2468 LKIVTYAAVSLSLAALLVAFVLLSLVRMLRSNLHSIHKHL-------AVALFLSQLVFVI 2520
Query: 247 GATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYL 306
G E L C V Y + + W LVE L++
Sbjct: 2521 GINQTENPFL------------------------CTVVAILLHYIYMSTFAWTLVESLHV 2556
Query: 307 HSLIFMAFFSEKKYLWGFTVFGWGLPAVF--VAVWVSVRATLANTGCWDLSSGNKKWIIQ 364
+ ++ + + + V GWG+PA+ +AV + + CW W
Sbjct: 2557 YRMLTEVRNIDTGPMRFYYVVGWGIPAIVTGLAVGLDPQGYGNPDFCWLSLQDTLIWSFA 2616
Query: 365 VPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVF 424
PI A I++N + VL+ K+ ++ LL++ +L+ L +++
Sbjct: 2617 GPIGAVIIIN-----TVTSVLSAKVSCQRKHHYYGKKGIVSLLRTAFLLLLLISATWLLG 2671
Query: 425 MATPYTEVSGTLWQVQMHYEM-LFNSFQGFFVAIIYCFCNGEVQAEIK 471
+ + + HY +F+ QG FV + +C N EV+ +K
Sbjct: 2672 LLAVNRDA------LSFHYLFAIFSGLQGPFVLLFHCVLNQEVRKHLK 2713
>gi|59710093 G-protein coupled receptor 112 [Homo sapiens]
Length = 3080
Score = 64.7 bits (156), Expect = 2e-10
Identities = 50/201 (24%), Positives = 92/201 (45%), Gaps = 25/201 (12%)
Query: 281 CRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAF-FSEKKYLWGFTVFGWGLPAVFVAVW 339
C A YFL ++ W+ +E ++++ + F Y+ F + GWG+PA+ VA+
Sbjct: 2809 CITAAVALHYFLLVSFTWMGLEAVHMYLALVKVFNIYIPNYILKFCLVGWGIPAIMVAIT 2868
Query: 340 VSVRATLANT------GCWDLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETN 393
VSV+ L T CW I + ++A L F++ ++ + T L + N
Sbjct: 2869 VSVKKDLYGTLSPTTPFCWIKDDS----IFYISVVAYFCLIFLMNLS---MFCTVLVQLN 2921
Query: 394 AGRCDTRQQYRKL----LKSTLVLMPLFGVHY-IVFMATPYTEVSGTLWQVQMHYEMLFN 448
+ + ++ RK+ LK T+ L L G+ + F A G + ++ +FN
Sbjct: 2922 SVKSQIQKTRRKMILHDLKGTMSLTFLLGLTWGFAFFAW------GPMRNFFLYLFAIFN 2975
Query: 449 SFQGFFVAIIYCFCNGEVQAE 469
+ QGFF+ + +C V+ +
Sbjct: 2976 TLQGFFIFVFHCVMKESVREQ 2996
>gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]
Length = 995
Score = 63.2 bits (152), Expect = 7e-10
Identities = 46/213 (21%), Positives = 92/213 (43%), Gaps = 29/213 (13%)
Query: 281 CRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSE-KKYLWGFTVFGWGLPAVFVAVW 339
C F YFL ++ W+ +E +++ + F + +KY+ F + GWG+PAV V +
Sbjct: 672 CISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCIVGWGVPAVVVTII 731
Query: 340 VSVRATLANTGCW---------DLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKL- 389
+++ G + D N + + ++ + F+L +++ V+ +L
Sbjct: 732 LTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVLVQLC 791
Query: 390 -----RETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYE 444
++ A R + Q R + T +L +G + + G + M+
Sbjct: 792 RIKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFFAW---------GPVNVTFMYLF 842
Query: 445 MLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRW 477
+FN+ QGFF+ I YC + ++K W R+
Sbjct: 843 AIFNTLQGFFIFIFYCV----AKENVRKQWRRY 871
>gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]
Length = 1003
Score = 63.2 bits (152), Expect = 7e-10
Identities = 46/213 (21%), Positives = 92/213 (43%), Gaps = 29/213 (13%)
Query: 281 CRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSE-KKYLWGFTVFGWGLPAVFVAVW 339
C F YFL ++ W+ +E +++ + F + +KY+ F + GWG+PAV V +
Sbjct: 680 CISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCIVGWGVPAVVVTII 739
Query: 340 VSVRATLANTGCW---------DLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKL- 389
+++ G + D N + + ++ + F+L +++ V+ +L
Sbjct: 740 LTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVLVQLC 799
Query: 390 -----RETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYE 444
++ A R + Q R + T +L +G + + G + M+
Sbjct: 800 RIKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFFAW---------GPVNVTFMYLF 850
Query: 445 MLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRW 477
+FN+ QGFF+ I YC + ++K W R+
Sbjct: 851 AIFNTLQGFFIFIFYCV----AKENVRKQWRRY 879
>gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]
Length = 1017
Score = 63.2 bits (152), Expect = 7e-10
Identities = 46/213 (21%), Positives = 92/213 (43%), Gaps = 29/213 (13%)
Query: 281 CRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSE-KKYLWGFTVFGWGLPAVFVAVW 339
C F YFL ++ W+ +E +++ + F + +KY+ F + GWG+PAV V +
Sbjct: 694 CISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCIVGWGVPAVVVTII 753
Query: 340 VSVRATLANTGCW---------DLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKL- 389
+++ G + D N + + ++ + F+L +++ V+ +L
Sbjct: 754 LTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVLVQLC 813
Query: 390 -----RETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYE 444
++ A R + Q R + T +L +G + + G + M+
Sbjct: 814 RIKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFFAW---------GPVNVTFMYLF 864
Query: 445 MLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRW 477
+FN+ QGFF+ I YC + ++K W R+
Sbjct: 865 AIFNTLQGFFIFIFYCV----AKENVRKQWRRY 893
>gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]
Length = 1014
Score = 63.2 bits (152), Expect = 7e-10
Identities = 46/213 (21%), Positives = 92/213 (43%), Gaps = 29/213 (13%)
Query: 281 CRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSE-KKYLWGFTVFGWGLPAVFVAVW 339
C F YFL ++ W+ +E +++ + F + +KY+ F + GWG+PAV V +
Sbjct: 691 CISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCIVGWGVPAVVVTII 750
Query: 340 VSVRATLANTGCW---------DLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKL- 389
+++ G + D N + + ++ + F+L +++ V+ +L
Sbjct: 751 LTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVLVQLC 810
Query: 390 -----RETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYE 444
++ A R + Q R + T +L +G + + G + M+
Sbjct: 811 RIKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFFAW---------GPVNVTFMYLF 861
Query: 445 MLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRW 477
+FN+ QGFF+ I YC + ++K W R+
Sbjct: 862 AIFNTLQGFFIFIFYCV----AKENVRKQWRRY 890
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.434
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,861,163
Number of Sequences: 37866
Number of extensions: 1230784
Number of successful extensions: 4707
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 61
Number of HSP's that attempted gapping in prelim test: 4384
Number of HSP's gapped (non-prelim): 201
length of query: 593
length of database: 18,247,518
effective HSP length: 108
effective length of query: 485
effective length of database: 14,157,990
effective search space: 6866625150
effective search space used: 6866625150
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.