Guide to the Human Genome
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Search of human proteins with 4505763

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505763 phosphoglycerate kinase 1 [Homo sapiens]
         (417 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4505763 phosphoglycerate kinase 1 [Homo sapiens]                   827   0.0  
gi|31543397 phosphoglycerate kinase 2 [Homo sapiens]                  744   0.0  
gi|40068518 phosphogluconate dehydrogenase [Homo sapiens]              32   1.1  
gi|94421471 ring finger protein 17 [Homo sapiens]                      31   1.8  
gi|157426875 F-box and leucine-rich repeat protein 18 [Homo sapi...    31   2.4  
gi|122937195 plasma membrane associated protein, S3-12 [Homo sap...    30   5.3  

>gi|4505763 phosphoglycerate kinase 1 [Homo sapiens]
          Length = 417

 Score =  827 bits (2135), Expect = 0.0
 Identities = 417/417 (100%), Positives = 417/417 (100%)

Query: 1   MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVL 60
           MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVL
Sbjct: 1   MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVL 60

Query: 61  MSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLE 120
           MSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLE
Sbjct: 61  MSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLE 120

Query: 121 NLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN 180
           NLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN
Sbjct: 121 NLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN 180

Query: 181 LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGM 240
           LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGM
Sbjct: 181 LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGM 240

Query: 241 AFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQ 300
           AFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQ
Sbjct: 241 AFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQ 300

Query: 301 ATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVV 360
           ATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVV
Sbjct: 301 ATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVV 360

Query: 361 KATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI 417
           KATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI
Sbjct: 361 KATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI 417


>gi|31543397 phosphoglycerate kinase 2 [Homo sapiens]
          Length = 417

 Score =  744 bits (1922), Expect = 0.0
 Identities = 364/417 (87%), Positives = 395/417 (94%)

Query: 1   MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVL 60
           MSLS KLTLDKLDV+GKRV+MRVDFNVPMK NQITNNQRIKA++PSIK+CLDNGAK+VVL
Sbjct: 1   MSLSKKLTLDKLDVRGKRVIMRVDFNVPMKKNQITNNQRIKASIPSIKYCLDNGAKAVVL 60

Query: 61  MSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLE 120
           MSHLGRPDGVPMPDKYSL PVAVELKSLLGKDVLFLKDCVG EVEKACANPA GSVILLE
Sbjct: 61  MSHLGRPDGVPMPDKYSLAPVAVELKSLLGKDVLFLKDCVGAEVEKACANPAPGSVILLE 120

Query: 121 NLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN 180
           NLRFHVEEEGKG+D SG K+KAEP KIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN
Sbjct: 121 NLRFHVEEEGKGQDPSGKKIKAEPDKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN 180

Query: 181 LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGM 240
           LP KA GFLMKKEL+YFAKALE+P RPFLAILGGAKVADKIQLI NMLDKVNEMIIGGGM
Sbjct: 181 LPHKASGFLMKKELDYFAKALENPVRPFLAILGGAKVADKIQLIKNMLDKVNEMIIGGGM 240

Query: 241 AFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQ 300
           A+TFLKVLNNMEIG SLFDEEGAKIVKD+M+KA+KNGV+IT PVDFVT DKFDENA+ G+
Sbjct: 241 AYTFLKVLNNMEIGASLFDEEGAKIVKDIMAKAQKNGVRITFPVDFVTGDKFDENAQVGK 300

Query: 301 ATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVV 360
           ATVASGI  GWMGLDCGPES+K +A+ V +A+ IVWNGP+GVFEW+AFA+GTKALMDE+V
Sbjct: 301 ATVASGISPGWMGLDCGPESNKNHAQVVAQARLIVWNGPLGVFEWDAFAKGTKALMDEIV 360

Query: 361 KATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI 417
           KATS+GCIT+IGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGK+LPGV+ALSN+
Sbjct: 361 KATSKGCITVIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKILPGVEALSNM 417


>gi|40068518 phosphogluconate dehydrogenase [Homo sapiens]
          Length = 483

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 35/135 (25%), Positives = 54/135 (40%), Gaps = 26/135 (19%)

Query: 149 AFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPF 208
           AF  ++SK+ D   N+A GT       +VG             + L      L+ P R  
Sbjct: 31  AFNRTVSKVDDFLANEAKGT------KVVGA------------QSLKEMVSKLKKPRRII 72

Query: 209 LAILGGAKVADKIQLINNMLDKVNEMIIGGGMAF-------TFLKVLNNMEIGTSLF-DE 260
           L +  G  V D I+ +  +LD  + +I GG   +         LK    + +G+ +   E
Sbjct: 73  LLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGE 132

Query: 261 EGAKIVKDLMSKAEK 275
           EGA+    LM    K
Sbjct: 133 EGARYGPSLMPGGNK 147


>gi|94421471 ring finger protein 17 [Homo sapiens]
          Length = 1623

 Score = 31.2 bits (69), Expect = 1.8
 Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 1/54 (1%)

Query: 244 FLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAK 297
           FLK++NN  +   +F EE   ++ DL  K   N +   +PV    A  F E AK
Sbjct: 598 FLKMVNNKAVSMKVFREEDGVLIVDL-QKPPPNKISSDMPVSLRDALVFMELAK 650


>gi|157426875 F-box and leucine-rich repeat protein 18 [Homo
           sapiens]
          Length = 718

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 23/79 (29%), Positives = 35/79 (44%), Gaps = 1/79 (1%)

Query: 68  DGVPMPDKYSLEPVAVELKSLLGKDV-LFLKDCVGPEVEKACANPAAGSVILLENLRFHV 126
           D  P  D+   +P    +    GK V + ++ C  P   +AC  P++    LL+NL F  
Sbjct: 427 DSAPRADRAPAQPAMHAVPRGFGKKVRVGVQSCPSPFSGQACPQPSSVFWSLLKNLPFLE 486

Query: 127 EEEGKGKDASGNKVKAEPA 145
             E  G + S    + EPA
Sbjct: 487 HLELIGSNFSSAMPRNEPA 505


>gi|122937195 plasma membrane associated protein, S3-12 [Homo
           sapiens]
          Length = 1357

 Score = 29.6 bits (65), Expect = 5.3
 Identities = 34/125 (27%), Positives = 48/125 (38%), Gaps = 10/125 (8%)

Query: 298 TGQATVASGIPAGWMGLDCGPE----SSKKYAEAVTRAKQIVWNG-PVGVFEWEAFARGT 352
           TG A VA G  A  MG+D        +       VT A  +       G+   +  A GT
Sbjct: 790 TGAANVAKG--AVQMGVDTAKTVLTGTKDTVCSGVTGAANVAKGAVQTGLKTTQNIATGT 847

Query: 353 KALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVD 412
           K  +   V   ++     + GG   T      T+D VS   TG   ++ L +G V  GVD
Sbjct: 848 KNTLGSGVTGAAKVAKGAVQGGLDTTKSVLTGTKDAVS---TGLTGAVNLAKGTVQTGVD 904

Query: 413 ALSNI 417
               +
Sbjct: 905 TSKTV 909


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,149,253
Number of Sequences: 37866
Number of extensions: 678094
Number of successful extensions: 1453
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1450
Number of HSP's gapped (non-prelim): 7
length of query: 417
length of database: 18,247,518
effective HSP length: 105
effective length of query: 312
effective length of database: 14,271,588
effective search space: 4452735456
effective search space used: 4452735456
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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