Search of human proteins with 4504937

Search of human proteins with 4504937

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504937 kynureninase (L-kynurenine hydrolase) isoform a
[Homo sapiens]
         (465 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504937 kynureninase (L-kynurenine hydrolase) isoform a [Homo...   947   0.0  
gi|74101437 kynureninase (L-kynurenine hydrolase) isoform b [Hom...   617   e-177
gi|45827765 UDP glycosyltransferase 1 family, polypeptide A6 iso...    30   4.7  
gi|55743118 RAB3 GTPase-activating protein [Homo sapiens]              30   6.1  
gi|221316741 N-acetyltransferase 10 isoform b [Homo sapiens]           29   7.9  
gi|221316723 N-acetyltransferase 10 isoform a [Homo sapiens]           29   7.9  
gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo ...    29   7.9  
gi|30794488 kinesin family member 27 [Homo sapiens]                    29   7.9  

>gi|4504937 kynureninase (L-kynurenine hydrolase) isoform a [Homo
           sapiens]
          Length = 465

 Score =  947 bits (2447), Expect = 0.0
 Identities = 465/465 (100%), Positives = 465/465 (100%)

Query: 1   MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS 60
           MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS
Sbjct: 1   MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS 60

Query: 61  LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM 120
           LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM
Sbjct: 61  LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM 120

Query: 121 KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG 180
           KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG
Sbjct: 121 KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG 180

Query: 181 LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG 240
           LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG
Sbjct: 181 LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG 240

Query: 241 QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP 300
           QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP
Sbjct: 241 QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP 300

Query: 301 ALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKK 360
           ALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKK
Sbjct: 301 ALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKK 360

Query: 361 SVLLTGYLEYLIKHNYGKDKAATKKPVVNIITPSHVEERGCQLTITFSVPNKDVFQELEK 420
           SVLLTGYLEYLIKHNYGKDKAATKKPVVNIITPSHVEERGCQLTITFSVPNKDVFQELEK
Sbjct: 361 SVLLTGYLEYLIKHNYGKDKAATKKPVVNIITPSHVEERGCQLTITFSVPNKDVFQELEK 420

Query: 421 RGVVCDKRNPNGIRVAPVPLYNSFHDVYKFTNLLTSILDSAETKN 465
           RGVVCDKRNPNGIRVAPVPLYNSFHDVYKFTNLLTSILDSAETKN
Sbjct: 421 RGVVCDKRNPNGIRVAPVPLYNSFHDVYKFTNLLTSILDSAETKN 465


>gi|74101437 kynureninase (L-kynurenine hydrolase) isoform b [Homo
           sapiens]
          Length = 307

 Score =  617 bits (1590), Expect = e-177
 Identities = 302/306 (98%), Positives = 303/306 (99%)

Query: 1   MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS 60
           MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS
Sbjct: 1   MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS 60

Query: 61  LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM 120
           LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM
Sbjct: 61  LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM 120

Query: 121 KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG 180
           KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG
Sbjct: 121 KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG 180

Query: 181 LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG 240
           LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG
Sbjct: 181 LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG 240

Query: 241 QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP 300
           QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP
Sbjct: 241 QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP 300

Query: 301 ALVGWF 306
           A   +F
Sbjct: 301 ARSEFF 306


>gi|45827765 UDP glycosyltransferase 1 family, polypeptide A6
           isoform 1 precursor [Homo sapiens]
          Length = 532

 Score = 30.0 bits (66), Expect = 4.7
 Identities = 17/65 (26%), Positives = 34/65 (52%), Gaps = 7/65 (10%)

Query: 176 LQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVI------LFSGVHFYTGQ 229
           L L G+ + + + ++ P++G   L ++DI+EV+   G  I V+      L     +YT +
Sbjct: 18  LALWGMVVGDKL-LVVPQDGSHWLSMKDIVEVLSDRGHEIVVVVPEVNLLLKESKYYTRK 76

Query: 230 HFNIP 234
            + +P
Sbjct: 77  IYPVP 81


>gi|55743118 RAB3 GTPase-activating protein [Homo sapiens]
          Length = 981

 Score = 29.6 bits (65), Expect = 6.1
 Identities = 22/78 (28%), Positives = 30/78 (38%), Gaps = 21/78 (26%)

Query: 271 CWCSYKYLNAGAGGIAGAFIHEKHAHTIKPALVGWFGHELSTRFKMDNKLQLIPGVCGFR 330
           C C   + + G  G+A                  W    L  RF+ +N   LIPG+    
Sbjct: 463 CLCMINFYHGGLKGVAHL----------------WQEFVLEMRFRWENNF-LIPGLA--- 502

Query: 331 ISNPPILLVCSLHASLEI 348
            S PP L  C LH  L++
Sbjct: 503 -SGPPDLRCCLLHQKLQM 519


>gi|221316741 N-acetyltransferase 10 isoform b [Homo sapiens]
          Length = 953

 Score = 29.3 bits (64), Expect = 7.9
 Identities = 13/33 (39%), Positives = 21/33 (63%)

Query: 52  QDLPPVDLSLVNKDENAIYFLGNSLGLQPKMVK 84
           +DLPP+ L L  +    + +LG S GL P+++K
Sbjct: 617 KDLPPLLLKLNERPAERLDYLGVSYGLTPRLLK 649


>gi|221316723 N-acetyltransferase 10 isoform a [Homo sapiens]
          Length = 1025

 Score = 29.3 bits (64), Expect = 7.9
 Identities = 13/33 (39%), Positives = 21/33 (63%)

Query: 52  QDLPPVDLSLVNKDENAIYFLGNSLGLQPKMVK 84
           +DLPP+ L L  +    + +LG S GL P+++K
Sbjct: 689 KDLPPLLLKLNERPAERLDYLGVSYGLTPRLLK 721


>gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo
           sapiens]
          Length = 1386

 Score = 29.3 bits (64), Expect = 7.9
 Identities = 18/63 (28%), Positives = 30/63 (47%), Gaps = 3/63 (4%)

Query: 290 IHEKHAHTIKPALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIF 349
           + + H + I+ A    F +EL  RF  D+K      +  F  +N  + L C LH S  ++
Sbjct: 338 VDDSHLNAIEDAS---FLYELEIRFSKDHKYPYQAPLVAFYSTNENLPLACRLHISEFLY 394

Query: 350 KQA 352
            +A
Sbjct: 395 DKA 397


>gi|30794488 kinesin family member 27 [Homo sapiens]
          Length = 1401

 Score = 29.3 bits (64), Expect = 7.9
 Identities = 16/59 (27%), Positives = 30/59 (50%)

Query: 157  KILLEAKAFPSDHYAIESQLQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSI 215
            K L  ++A  +D   I ++L L    + E    ++    EE  +I + +EV++KE D +
Sbjct: 972  KKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQL 1030


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.138    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,836,256
Number of Sequences: 37866
Number of extensions: 797300
Number of successful extensions: 1520
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1515
Number of HSP's gapped (non-prelim): 8
length of query: 465
length of database: 18,247,518
effective HSP length: 106
effective length of query: 359
effective length of database: 14,233,722
effective search space: 5109906198
effective search space used: 5109906198
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.