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Search of human proteins with 4502997
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502997 carboxypeptidase A1 precursor [Homo sapiens]
(419 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502997 carboxypeptidase A1 precursor [Homo sapiens] 851 0.0
gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo sa... 542 e-154
gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens] 534 e-152
gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens] 534 e-152
gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens] 489 e-138
gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens] 410 e-114
gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo s... 343 1e-94
gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens] 294 1e-79
gi|221316749 carboxypeptidase A3 precursor [Homo sapiens] 293 2e-79
gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein ... 257 2e-68
gi|27436871 carboxypeptidase O [Homo sapiens] 234 1e-61
gi|126273559 plasma carboxypeptidase B2 isoform b [Homo sapiens] 179 4e-45
gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens] 103 2e-22
gi|22202611 carboxypeptidase D precursor [Homo sapiens] 54 3e-07
gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens] 44 2e-04
gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens] 44 2e-04
gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens] 44 2e-04
gi|31652238 cut-like homeobox 1 isoform c [Homo sapiens] 40 0.003
gi|31652236 cut-like homeobox 1 isoform b [Homo sapiens] 40 0.003
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 33 0.63
gi|46370066 exostosin 1 [Homo sapiens] 32 1.1
gi|116734714 activin A receptor type II-like 1 [Homo sapiens] 31 1.8
gi|116734712 activin A receptor type II-like 1 [Homo sapiens] 31 1.8
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo... 31 2.4
gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo sap... 31 2.4
gi|53832021 carboxypeptidase M precursor [Homo sapiens] 30 3.1
gi|38327526 carboxypeptidase M precursor [Homo sapiens] 30 3.1
gi|6631081 carboxypeptidase M precursor [Homo sapiens] 30 3.1
gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens] 30 3.1
gi|31542244 leucine rich repeat and fibronectin type III domain ... 30 5.3
>gi|4502997 carboxypeptidase A1 precursor [Homo sapiens]
Length = 419
Score = 851 bits (2198), Expect = 0.0
Identities = 419/419 (100%), Positives = 419/419 (100%)
Query: 1 MRGLLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPG 60
MRGLLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPG
Sbjct: 1 MRGLLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPG 60
Query: 61 SPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYA 120
SPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYA
Sbjct: 61 SPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYA 120
Query: 121 TYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHS 180
TYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHS
Sbjct: 121 TYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHS 180
Query: 181 REWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTR 240
REWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTR
Sbjct: 181 REWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTR 240
Query: 241 SHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIK 300
SHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIK
Sbjct: 241 SHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIK 300
Query: 301 AFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQA 360
AFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQA
Sbjct: 301 AFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQA 360
Query: 361 SGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHPY 419
SGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHPY
Sbjct: 361 SGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHPY 419
>gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo
sapiens]
Length = 419
Score = 542 bits (1396), Expect = e-154
Identities = 263/419 (62%), Positives = 320/419 (76%), Gaps = 2/419 (0%)
Query: 1 MRGLLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPG 60
MR +L L G ++ E FVG QVL I ++E Q++ + +LE EHLQLDFW+ P PG
Sbjct: 3 MRLILFFGALFGHIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPG 62
Query: 61 SPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYA 120
VRVPF ++QAVK+FLES GI+Y MIEDVQ LLD+E E+M R R RS + FN+
Sbjct: 63 ETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGN-FNFG 121
Query: 121 TYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHS 180
YHTLEEI +D LVAE+P LVSK+ IG+++E RP+ VLKFSTGG K PAIW+D GIH+
Sbjct: 122 AYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-PAIWLDAGIHA 180
Query: 181 REWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTR 240
REWVTQA+ +W A KI DYG+D + T+ILD LDIFL VTNPDG+ F+ + NRMWRKTR
Sbjct: 181 REWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTR 240
Query: 241 SHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIK 300
S +GSLC+GVDPNRNWDAGFG GASSNPCS++YHG ANSEVEVKSIVDF+K HG +K
Sbjct: 241 SKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVK 300
Query: 301 AFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQA 360
AFI++HSYSQLLM+PYGYK + D DEL ++++ A +L SL+GTK+ G I IYQA
Sbjct: 301 AFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQA 360
Query: 361 SGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHPY 419
SG +IDW+Y GIKYSF FELRDTGRYGFLLPA QI+PTA+ETWL L IMEH +HPY
Sbjct: 361 SGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY 419
>gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens]
Length = 436
Score = 534 bits (1375), Expect = e-152
Identities = 252/418 (60%), Positives = 320/418 (76%)
Query: 2 RGLLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPGS 61
R LLV S +L A G+ +F G QVLR+ DE Q+ + +LE L+ ++DFWRGPA P
Sbjct: 19 RTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPSL 78
Query: 62 PIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYAT 121
P+D+RVPF ++ +K +LESHG++Y MI+D+Q LLDEE++ M R RST++F+Y++
Sbjct: 79 PVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSS 138
Query: 122 YHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHSR 181
YHTLEEIY ++D V E+ +VSKIQIGN++E + I VLKFSTGGS+ PAIWIDTGIHSR
Sbjct: 139 YHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIHSR 198
Query: 182 EWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRS 241
EW+T A+G+W A KI DYG+D T IL+ +DIF+E+VTNPDGFAFTHS NR+WRK +S
Sbjct: 199 EWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKS 258
Query: 242 HTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIKA 301
G CIGVD NRNW +GFG +G++SNPCSETYHG SE EV +IV+F+ HGN KA
Sbjct: 259 IRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGNFKA 318
Query: 302 FISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQAS 361
ISIHSYSQ+LMYPYG EPV +Q EL L+K AV AL ++G ++ +GSI +Y AS
Sbjct: 319 LISIHSYSQMLMYPYGRLLEPVSNQRELYDLAKDAVEALYKVHGIEYIFGSISTTLYVAS 378
Query: 362 GSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHPY 419
G T+DW Y GIKY+F+FELRDTG+YGFLLPA+QIIPTA+ETW+AL TIMEHTLNHPY
Sbjct: 379 GITVDWAYDSGIKYAFSFELRDTGQYGFLLPATQIIPTAQETWMALRTIMEHTLNHPY 436
>gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens]
Length = 436
Score = 534 bits (1375), Expect = e-152
Identities = 252/418 (60%), Positives = 320/418 (76%)
Query: 2 RGLLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPGS 61
R LLV S +L A G+ +F G QVLR+ DE Q+ + +LE L+ ++DFWRGPA P
Sbjct: 19 RTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPSL 78
Query: 62 PIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYAT 121
P+D+RVPF ++ +K +LESHG++Y MI+D+Q LLDEE++ M R RST++F+Y++
Sbjct: 79 PVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSS 138
Query: 122 YHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHSR 181
YHTLEEIY ++D V E+ +VSKIQIGN++E + I VLKFSTGGS+ PAIWIDTGIHSR
Sbjct: 139 YHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIHSR 198
Query: 182 EWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRS 241
EW+T A+G+W A KI DYG+D T IL+ +DIF+E+VTNPDGFAFTHS NR+WRK +S
Sbjct: 199 EWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKS 258
Query: 242 HTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIKA 301
G CIGVD NRNW +GFG +G++SNPCSETYHG SE EV +IV+F+ HGN KA
Sbjct: 259 IRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGNFKA 318
Query: 302 FISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQAS 361
ISIHSYSQ+LMYPYG EPV +Q EL L+K AV AL ++G ++ +GSI +Y AS
Sbjct: 319 LISIHSYSQMLMYPYGRLLEPVSNQRELYDLAKDAVEALYKVHGIEYIFGSISTTLYVAS 378
Query: 362 GSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHPY 419
G T+DW Y GIKY+F+FELRDTG+YGFLLPA+QIIPTA+ETW+AL TIMEHTLNHPY
Sbjct: 379 GITVDWAYDSGIKYAFSFELRDTGQYGFLLPATQIIPTAQETWMALRTIMEHTLNHPY 436
>gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens]
Length = 421
Score = 489 bits (1258), Expect = e-138
Identities = 229/421 (54%), Positives = 307/421 (72%), Gaps = 2/421 (0%)
Query: 1 MRGLLVLSVLLGA-VFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHP 59
MR +L + L+G+ + G+E F G QVLRI+V + ++ K+ +L + +L+L+FW+ P+
Sbjct: 1 MRWILFIGALIGSSICGQEKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSF 60
Query: 60 GSPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNY 119
P+DV VP S+QA K FL S G+ Y IED+Q+LLD E ++M + RS++ FNY
Sbjct: 61 NRPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNY 120
Query: 120 ATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTG-GSKRPAIWIDTGI 178
YH+LE IY +D + A+ P L +++IG+++E RP+YVLKFSTG G +RPA+W++ GI
Sbjct: 121 GAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGI 180
Query: 179 HSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRK 238
HSREW++QA+ +W A+KI DY +D A T+IL+ +DIFL V NPDG+ +T + NR+WRK
Sbjct: 181 HSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRK 240
Query: 239 TRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGN 298
TRS GS CIG DPNRNW+A F GAS NPCSE YHG ANSEVEVKS+VDF++ HGN
Sbjct: 241 TRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGN 300
Query: 299 IKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIY 358
K FI +HSYSQLLMYPYGY + PD +ELD++++ A ALAS+ GT++ G +Y
Sbjct: 301 FKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPTCTTVY 360
Query: 359 QASGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHP 418
ASGS+IDW Y GIK++FTFELRDTG YGFLLPA+QIIPTA+ETWL L TIMEH ++
Sbjct: 361 PASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRDNL 420
Query: 419 Y 419
Y
Sbjct: 421 Y 421
>gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens]
Length = 403
Score = 410 bits (1053), Expect = e-114
Identities = 193/328 (58%), Positives = 247/328 (75%)
Query: 2 RGLLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPGS 61
R LLV S +L A G+ +F G QVLR+ DE Q+ + +LE L+ ++DFWRGPA P
Sbjct: 19 RTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPSL 78
Query: 62 PIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYAT 121
P+D+RVPF ++ +K +LESHG++Y MI+D+Q LLDEE++ M R RST++F+Y++
Sbjct: 79 PVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSS 138
Query: 122 YHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHSR 181
YHTLEEIY ++D V E+ +VSKIQIGN++E + I VLKFSTGGS+ PAIWIDTGIHSR
Sbjct: 139 YHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIHSR 198
Query: 182 EWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRS 241
EW+T A+G+W A KI DYG+D T IL+ +DIF+E+VTNPDGFAFTHS NR+WRK +S
Sbjct: 199 EWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKS 258
Query: 242 HTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIKA 301
G CIGVD NRNW +GFG +G++SNPCSETYHG SE EV +IV+F+ HGN KA
Sbjct: 259 IRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGNFKA 318
Query: 302 FISIHSYSQLLMYPYGYKTEPVPDQDEL 329
ISIHSYSQ+LMYPYG EPV +Q EL
Sbjct: 319 LISIHSYSQMLMYPYGRLLEPVSNQREL 346
>gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo
sapiens]
Length = 417
Score = 343 bits (881), Expect = 1e-94
Identities = 181/421 (42%), Positives = 261/421 (61%), Gaps = 14/421 (3%)
Query: 4 LLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPA----HP 59
+LV L A G E F G +V R++V DE + ++EL Q+DFW+ + P
Sbjct: 6 VLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTT--QIDFWKPDSVTQIKP 63
Query: 60 GSPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNY 119
S +D RV V+ L+ + + Y+ +I +++++++ + F SR R+T +Y
Sbjct: 64 HSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQ------FDSRVRATG-HSY 116
Query: 120 ATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIH 179
Y+ E I + + ENP L+S+ IG T+EGR IY+LK G +PAI++D G H
Sbjct: 117 EKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFH 176
Query: 180 SREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKT 239
+REW++ A WF ++ + YG++ T +LD LD ++ V N DG+ +T + +R WRKT
Sbjct: 177 AREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKT 236
Query: 240 RSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDH-GN 298
RS GS CIG DPNRN+DAG+ GAS NPC ETY G A SE E K++ DF+++ +
Sbjct: 237 RSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSS 296
Query: 299 IKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIY 358
IKA+++IHSYSQ+++YPY Y + + EL+ L+KA V LASL+GTK+ YG IY
Sbjct: 297 IKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIY 356
Query: 359 QASGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHP 418
A+G + DW Y QGI+YSFTFELRDTGRYGFLLP SQI T +ET+LA+ + + L H
Sbjct: 357 PAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLEHL 416
Query: 419 Y 419
Y
Sbjct: 417 Y 417
>gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens]
Length = 437
Score = 294 bits (752), Expect = 1e-79
Identities = 155/401 (38%), Positives = 233/401 (58%), Gaps = 9/401 (2%)
Query: 20 FVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPA----HPGSPIDVRVPFPSIQAV 75
+ G +V+R E + +K++ L++D W+ + G+ DV +P +A+
Sbjct: 37 YAGDKVIRFIPKTEEEAYALKKIS--YQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRAL 94
Query: 76 KIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDFLDLL 135
FL+ I Y+ +IED+Q L E+ + R+R RS +NY YH+LEEI +++ L
Sbjct: 95 LAFLQEANIQYKVLIEDLQKTL-EKGSSLHTQRNR-RSLSGYNYEVYHSLEEIQNWMHHL 152
Query: 136 VAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHSREWVTQASGVWFAKK 195
+ L+ IG +YEGR +++LK + A+WID GIH+REW+ A WF K+
Sbjct: 153 NKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKE 212
Query: 196 ITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNR 255
Y D A +L+ L ++ V N DG+ F+ + +R WRKTRS + C GVD NR
Sbjct: 213 ALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANR 272
Query: 256 NWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDH-GNIKAFISIHSYSQLLMY 314
NW + GAS +PC +TY G F SE EVK++ +F++ H +I+A++S H+Y+Q+L+Y
Sbjct: 273 NWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLY 332
Query: 315 PYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQASGSTIDWTYSQGIK 374
PY YK +P+ ++ + AV AL S+YG ++ YG +Y +SGS++DW Y GI
Sbjct: 333 PYSYKYATIPNFRCVESAAYKAVNALQSVYGVRYRYGPASTTLYVSSGSSMDWAYKNGIP 392
Query: 375 YSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTL 415
Y+F FELRDTG +GFLLP I PT ET LA+ I H L
Sbjct: 393 YAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLL 433
>gi|221316749 carboxypeptidase A3 precursor [Homo sapiens]
Length = 417
Score = 293 bits (750), Expect = 2e-79
Identities = 155/403 (38%), Positives = 241/403 (59%), Gaps = 13/403 (3%)
Query: 20 FVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWR-GPAH---PGSPIDVRVPFPSIQAV 75
F +V R+ DE Q +K+L +LDFW G H +D RV QA+
Sbjct: 21 FDREKVFRVKPQDEKQADIIKDLAKTN--ELDFWYPGATHHVAANMMVDFRVSEKESQAI 78
Query: 76 KIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDFLDLL 135
+ L+ + + YE +I D+Q EE E+ F + + YA Y+ E+I + + +
Sbjct: 79 QSALDQNKMHYEILIHDLQ----EEIEKQFDVKEDIPGRHS--YAKYNNWEKIVAWTEKM 132
Query: 136 VAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHSREWVTQASGVWFAKK 195
+ + P +VS+I+IG+T E P+YVLK +R AI+ D GIH+REWV+ A WF +
Sbjct: 133 MDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREWVSPAFCQWFVYQ 192
Query: 196 ITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNR 255
T+ YG++ T +LD ++ ++ V N DG+ ++ + NRMWRK RS S CIG D NR
Sbjct: 193 ATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNSKCIGTDLNR 252
Query: 256 NWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGN-IKAFISIHSYSQLLMY 314
N++A + +++PC++ Y G SE E K++ +F++ H N IK +I+ HSYSQ+L++
Sbjct: 253 NFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVYITFHSYSQMLLF 312
Query: 315 PYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQASGSTIDWTYSQGIK 374
PYGY ++ P+ ++L +++K L++ Y T++ YG I IY SGS++DW Y GIK
Sbjct: 313 PYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISGSSLDWAYDLGIK 372
Query: 375 YSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNH 417
++F FELRD G++GFLLP S+I PT +ET LA+ I ++ L H
Sbjct: 373 HTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYILKH 415
>gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein
[Homo sapiens]
Length = 423
Score = 257 bits (656), Expect = 2e-68
Identities = 142/350 (40%), Positives = 210/350 (60%), Gaps = 8/350 (2%)
Query: 72 IQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDF 131
+ VK L GI ++ DV+ L+ Q+Q+ R++ ++ Y YH+L EIY +
Sbjct: 77 VDNVKAHLNVSGIPCSVLLADVEDLI---QQQISNDTVSPRASASY-YEQYHSLNEIYSW 132
Query: 132 LDLLVAENPHLVSKIQIGNTYEGRPIYVLKFS-TGGSKRPAIWIDTGIHSREWVTQASGV 190
++ + +P +++KI IG+++E P+YVLK S + + AIWID GIH+REW++ A +
Sbjct: 133 IEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCL 192
Query: 191 WFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIG 250
WF ITQ YG +T +L +D ++ V N DG+ ++ NRMWRK RS A + CIG
Sbjct: 193 WFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIG 252
Query: 251 VDPNRNWDAGFGL-SGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGN-IKAFISIHSY 308
D NRN+ + GASS+ CSETY G + SE EVK++ F++ + N IKA+IS+HSY
Sbjct: 253 TDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSY 312
Query: 309 SQLLMYPYGYKTEPVPDQDELDQLSKAAVTAL-ASLYGTKFNYGSIIKAIYQASGSTIDW 367
SQ +++PY Y D +EL ++ AV A+ + T++ +G + +Y A G DW
Sbjct: 313 SQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDW 372
Query: 368 TYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNH 417
Y GIKYSFT ELRDTG YGFLLP I PT +E + A+ I H + +
Sbjct: 373 IYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRN 422
>gi|27436871 carboxypeptidase O [Homo sapiens]
Length = 374
Score = 234 bits (596), Expect = 1e-61
Identities = 117/302 (38%), Positives = 186/302 (61%), Gaps = 2/302 (0%)
Query: 113 STDTFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFST-GGSKRPA 171
S +T++Y YH + EIY+++ + + +V++ +G TYE P+Y LK S G+ +
Sbjct: 41 SLETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKI 100
Query: 172 IWIDTGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHS 231
IW+D GIH+REW+ A WF K+I Q++ +++ +L LD ++ V N DG+ +T +
Sbjct: 101 IWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWT 160
Query: 232 TNRMWRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVD 291
T+R+WRK+RS C G D NRN++A + GAS N +T+ G SE E K++
Sbjct: 161 TDRLWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVAS 220
Query: 292 FVKDH-GNIKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNY 350
F++ +I F+++HSY QL++ PYGY + E+ Q+ + A AL + YGT +
Sbjct: 221 FIESKKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAANALKAKYGTNYRV 280
Query: 351 GSIIKAIYQASGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTI 410
GS +Y +SGS+ DW GI +S+TFELRD+G YGF+LP +QI PT +ET A+L++
Sbjct: 281 GSSADILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETMEAVLSV 340
Query: 411 ME 412
++
Sbjct: 341 LD 342
>gi|126273559 plasma carboxypeptidase B2 isoform b [Homo sapiens]
Length = 360
Score = 179 bits (454), Expect = 4e-45
Identities = 110/311 (35%), Positives = 165/311 (53%), Gaps = 45/311 (14%)
Query: 72 IQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDF 131
+ VK L GI ++ DV+ L+ Q+Q+ R++ ++ Y YH+L EIY +
Sbjct: 77 VDNVKAHLNVSGIPCSVLLADVEDLI---QQQISNDTVSPRASASY-YEQYHSLNEIYSW 132
Query: 132 LDLLVAENPHLVSKIQIGNTYEGRPIYVLKFS-TGGSKRPAIWIDTGIHSREWVTQASGV 190
++ + +P +++KI IG+++E P+YVLK S + + AIWID GIH+REW++ A +
Sbjct: 133 IEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCL 192
Query: 191 WFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIG 250
WF NRMWRK RS A + CIG
Sbjct: 193 WFI-------------------------------------GHNRMWRKNRSFYANNHCIG 215
Query: 251 VDPNRNWDAGFGLS-GASSNPCSETYHGKFANSEVEVKSIVDFVKDHGN-IKAFISIHSY 308
D NRN+ + GASS+ CSETY G + SE EVK++ F++ + N IKA+IS+HSY
Sbjct: 216 TDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSY 275
Query: 309 SQLLMYPYGYKTEPVPDQDELDQLSKAAVTAL-ASLYGTKFNYGSIIKAIYQASGSTIDW 367
SQ +++PY Y D +EL ++ AV A+ + T++ +G + +Y A G DW
Sbjct: 276 SQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDW 335
Query: 368 TYSQGIKYSFT 378
Y GIKYS T
Sbjct: 336 IYDLGIKYSVT 346
>gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens]
Length = 193
Score = 103 bits (258), Expect = 2e-22
Identities = 48/116 (41%), Positives = 67/116 (57%)
Query: 142 LVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHSREWVTQASGVWFAKKITQDYG 201
L+ IG +YEGR +++LK + A+WID GIH+REW+ A WF K+ Y
Sbjct: 11 LIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYK 70
Query: 202 QDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNRNW 257
D A +L+ L ++ V N DG+ F+ + +R WRKTRS + C GVD NRNW
Sbjct: 71 SDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNW 126
Score = 68.2 bits (165), Expect = 1e-11
Identities = 32/56 (57%), Positives = 38/56 (67%)
Query: 360 ASGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTL 415
+SGS++DW Y GI Y+F FELRDTG +GFLLP I PT ET LA+ I H L
Sbjct: 134 SSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLL 189
>gi|22202611 carboxypeptidase D precursor [Homo sapiens]
Length = 1380
Score = 53.5 bits (127), Expect = 3e-07
Identities = 54/252 (21%), Positives = 102/252 (40%), Gaps = 34/252 (13%)
Query: 86 YETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDFLDLLVAENPHLVSK 145
+ET+I+D+ + + + + R+ S YH+ +++ +FL LV PH+ +
Sbjct: 902 FETLIKDLSA-----ENGLESLMLRSSSNLALALYRYHSYKDLSEFLRGLVMNYPHITNL 956
Query: 146 IQIGNTYEGRPIYVLKFS----TGGSKRPAIWIDTGIHSREWVTQASGVWFAKKITQDYG 201
+G + E R I+ L+ S + P I GIH V + A+ + +Y
Sbjct: 957 TNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLNYK 1016
Query: 202 QDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNRNWDAGF 261
++ A T ++D I + NPDG R+ + IG R D
Sbjct: 1017 KNPAVTQLVDRTRIVIVPSLNPDG-----------RERAQEKDCTSKIGQTNARGKDLDT 1065
Query: 262 GLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIKAFISIHSYSQLLMYPYGYKTE 321
+ +S P E K+I++ + + +++ S L+ YPY +
Sbjct: 1066 DFTNNASQP--------------ETKAIIENLIQKQDFSLSVALDGGSMLVTYPYDKPVQ 1111
Query: 322 PVPDQDELDQLS 333
V +++ L L+
Sbjct: 1112 TVENKETLKHLA 1123
Score = 44.7 bits (104), Expect = 2e-04
Identities = 55/265 (20%), Positives = 99/265 (37%), Gaps = 70/265 (26%)
Query: 122 YHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTG-GS------------- 167
YH E + A P L IG + EGRP++VL+ + G GS
Sbjct: 59 YHEEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGPDAAG 118
Query: 168 ---------KRPAIWIDTGIHSREWVTQASGVWFAKKITQDYGQ-DAAFTAILDTLDIFL 217
RP + + +H E V++ ++ A+++ Y + D +L+T D++L
Sbjct: 119 PDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYL 178
Query: 218 EIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHG 277
NPDGF + R D GFG G S + G
Sbjct: 179 LPSLNPDGF-------------------------ERAREGDCGFGDGGPSGASGRDNSRG 213
Query: 278 KFANSEV----------------EVKSIVDFVKDHGNIKAFISIHSYSQLLMYPYG---- 317
+ N EV++++++++ + + + ++H S + YP+
Sbjct: 214 RDLNRSFPDQFSTGEPPALDEVPEVRALIEWIRRNKFVLSG-NLHGGSVVASYPFDDSPE 272
Query: 318 YKTEPVPDQDELDQLSKAAVTALAS 342
+K + + D++ K A AS
Sbjct: 273 HKATGIYSKTSDDEVFKYLAKAYAS 297
Score = 34.3 bits (77), Expect = 0.22
Identities = 24/109 (22%), Positives = 45/109 (41%), Gaps = 4/109 (3%)
Query: 122 YHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKR----PAIWIDTG 177
+H ++ FL E P++ +G + E R +YV++ S P
Sbjct: 503 HHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGN 562
Query: 178 IHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGF 226
+H E V + + + + +++G D T ++ I L NPDG+
Sbjct: 563 MHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGY 611
>gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens]
Length = 515
Score = 44.3 bits (103), Expect = 2e-04
Identities = 63/299 (21%), Positives = 116/299 (38%), Gaps = 39/299 (13%)
Query: 116 TFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSK----RPA 171
TF ++H+ ++ L + H+ IG +++GR + V++FS+ + P
Sbjct: 44 TFIRFSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPE 103
Query: 172 IWIDTGIHSREWVTQASGVWFAKKITQDY-GQDAAFTAILDTLDIFLEIVTNPDGF---A 227
+ + IH E + ++ A+ + +Y + +L+T I L NPDG+ A
Sbjct: 104 VKLIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAA 163
Query: 228 FTHSTNRMWRKTRSHTAGSLCIGVDPNRNW----DAGFGLS---GASSNPCSETYHGKFA 280
+ W R + +D NRN+ + L+ GA S+ H +
Sbjct: 164 AEGAGYNGWTSGRQNAQ-----NLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWG 218
Query: 281 NSEVEVKSIVDFVKDHGNIKAFISIHSYSQLLMYPYGYKT--------EPVPDQDELDQL 332
E K+I+ +++ + + S+H ++ YP+ + P PD+ L
Sbjct: 219 KVAPETKAIMKWMQTIPFVLS-ASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLL 277
Query: 333 SKAAVTALASLY--------GTKFNYGSIIKAI--YQASGSTIDWTYSQGIKYSFTFEL 381
S+A + G GSII Y +G D+ Y + T EL
Sbjct: 278 SRAYADVHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVEL 336
>gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens]
Length = 641
Score = 44.3 bits (103), Expect = 2e-04
Identities = 63/299 (21%), Positives = 116/299 (38%), Gaps = 39/299 (13%)
Query: 116 TFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSK----RPA 171
TF ++H+ ++ L + H+ IG +++GR + V++FS+ + P
Sbjct: 170 TFIRFSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPE 229
Query: 172 IWIDTGIHSREWVTQASGVWFAKKITQDY-GQDAAFTAILDTLDIFLEIVTNPDGF---A 227
+ + IH E + ++ A+ + +Y + +L+T I L NPDG+ A
Sbjct: 230 VKLIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAA 289
Query: 228 FTHSTNRMWRKTRSHTAGSLCIGVDPNRNW----DAGFGLS---GASSNPCSETYHGKFA 280
+ W R + +D NRN+ + L+ GA S+ H +
Sbjct: 290 AEGAGYNGWTSGRQNAQ-----NLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWG 344
Query: 281 NSEVEVKSIVDFVKDHGNIKAFISIHSYSQLLMYPYGYKT--------EPVPDQDELDQL 332
E K+I+ +++ + + S+H ++ YP+ + P PD+ L
Sbjct: 345 KVAPETKAIMKWMQTIPFVLS-ASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLL 403
Query: 333 SKAAVTALASLY--------GTKFNYGSIIKAI--YQASGSTIDWTYSQGIKYSFTFEL 381
S+A + G GSII Y +G D+ Y + T EL
Sbjct: 404 SRAYADVHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVEL 462
>gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens]
Length = 652
Score = 44.3 bits (103), Expect = 2e-04
Identities = 63/299 (21%), Positives = 116/299 (38%), Gaps = 39/299 (13%)
Query: 116 TFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSK----RPA 171
TF ++H+ ++ L + H+ IG +++GR + V++FS+ + P
Sbjct: 181 TFIRFSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPE 240
Query: 172 IWIDTGIHSREWVTQASGVWFAKKITQDY-GQDAAFTAILDTLDIFLEIVTNPDGF---A 227
+ + IH E + ++ A+ + +Y + +L+T I L NPDG+ A
Sbjct: 241 VKLIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAA 300
Query: 228 FTHSTNRMWRKTRSHTAGSLCIGVDPNRNW----DAGFGLS---GASSNPCSETYHGKFA 280
+ W R + +D NRN+ + L+ GA S+ H +
Sbjct: 301 AEGAGYNGWTSGRQNAQ-----NLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWG 355
Query: 281 NSEVEVKSIVDFVKDHGNIKAFISIHSYSQLLMYPYGYKT--------EPVPDQDELDQL 332
E K+I+ +++ + + S+H ++ YP+ + P PD+ L
Sbjct: 356 KVAPETKAIMKWMQTIPFVLS-ASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLL 414
Query: 333 SKAAVTALASLY--------GTKFNYGSIIKAI--YQASGSTIDWTYSQGIKYSFTFEL 381
S+A + G GSII Y +G D+ Y + T EL
Sbjct: 415 SRAYADVHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVEL 473
>gi|31652238 cut-like homeobox 1 isoform c [Homo sapiens]
Length = 676
Score = 40.4 bits (93), Expect = 0.003
Identities = 26/94 (27%), Positives = 47/94 (50%), Gaps = 7/94 (7%)
Query: 66 RVPFPSIQAVKIFL----ESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYAT 121
++P P +A +F + G E ++ + S++ ++E+ FR+R + + N
Sbjct: 468 KIPEPIKEATALFYGPAAPASGALPEGQVDSLLSIISSQRER---FRARNQELEAENRLA 524
Query: 122 YHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGR 155
HTL+ + LD L A+N L KI+ +Y GR
Sbjct: 525 QHTLQALQSELDSLRADNIKLFEKIKFLQSYPGR 558
>gi|31652236 cut-like homeobox 1 isoform b [Homo sapiens]
Length = 678
Score = 40.4 bits (93), Expect = 0.003
Identities = 26/94 (27%), Positives = 47/94 (50%), Gaps = 7/94 (7%)
Query: 66 RVPFPSIQAVKIFL----ESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYAT 121
++P P +A +F + G E ++ + S++ ++E+ FR+R + + N
Sbjct: 470 KIPEPIKEATALFYGPAAPASGALPEGQVDSLLSIISSQRER---FRARNQELEAENRLA 526
Query: 122 YHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGR 155
HTL+ + LD L A+N L KI+ +Y GR
Sbjct: 527 QHTLQALQSELDSLRADNIKLFEKIKFLQSYPGR 560
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 32.7 bits (73), Expect = 0.63
Identities = 17/62 (27%), Positives = 34/62 (54%)
Query: 85 SYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDFLDLLVAENPHLVS 144
+++ ++ + + LDE Q ++ A + +RS T + + EE+ D L+ L EN +L
Sbjct: 1452 NFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQE 1511
Query: 145 KI 146
+I
Sbjct: 1512 EI 1513
>gi|46370066 exostosin 1 [Homo sapiens]
Length = 746
Score = 32.0 bits (71), Expect = 1.1
Identities = 33/126 (26%), Positives = 46/126 (36%), Gaps = 6/126 (4%)
Query: 197 TQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNRN 256
T D Q F LDTLD + +W R+H +L G P+
Sbjct: 145 TSDPSQACLFVLSLDTLDRDQLSPQYVHNLRSKVQSLHLWNNGRNHLIFNLYSGTWPDYT 204
Query: 257 WDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDH---GNIKAFISIHSYSQLLM 313
D GF + A S + N +V SI F KDH G + F+ ++ L
Sbjct: 205 EDVGFDIGQAMLAKASISTENFRPNFDV---SIPLFSKDHPRTGGERGFLKFNTIPPLRK 261
Query: 314 YPYGYK 319
Y +K
Sbjct: 262 YMLVFK 267
>gi|116734714 activin A receptor type II-like 1 [Homo sapiens]
Length = 503
Score = 31.2 bits (69), Expect = 1.8
Identities = 35/122 (28%), Positives = 52/122 (42%), Gaps = 10/122 (8%)
Query: 51 DFWRGPAHPGSPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSR 110
+ WRG H G + V++ F S F E+ Y T++ ++L M SR
Sbjct: 215 EVWRGLWH-GESVAVKI-FSSRDEQSWFRETE--IYNTVLLRHDNILGFIASDM---TSR 267
Query: 111 ARSTDTFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRP 170
ST + YH +YDFL E PHL ++ + ++V F T G +P
Sbjct: 268 NSSTQLWLITHYHEHGSLYDFLQRQTLE-PHLALRLAVSAACGLAHLHVEIFGTQG--KP 324
Query: 171 AI 172
AI
Sbjct: 325 AI 326
>gi|116734712 activin A receptor type II-like 1 [Homo sapiens]
Length = 503
Score = 31.2 bits (69), Expect = 1.8
Identities = 35/122 (28%), Positives = 52/122 (42%), Gaps = 10/122 (8%)
Query: 51 DFWRGPAHPGSPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSR 110
+ WRG H G + V++ F S F E+ Y T++ ++L M SR
Sbjct: 215 EVWRGLWH-GESVAVKI-FSSRDEQSWFRETE--IYNTVLLRHDNILGFIASDM---TSR 267
Query: 111 ARSTDTFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRP 170
ST + YH +YDFL E PHL ++ + ++V F T G +P
Sbjct: 268 NSSTQLWLITHYHEHGSLYDFLQRQTLE-PHLALRLAVSAACGLAHLHVEIFGTQG--KP 324
Query: 171 AI 172
AI
Sbjct: 325 AI 326
>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
sapiens]
Length = 1158
Score = 30.8 bits (68), Expect = 2.4
Identities = 44/239 (18%), Positives = 90/239 (37%), Gaps = 36/239 (15%)
Query: 113 STDTFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSK---- 168
+TD ++ +H+ +++ + ++ E P + +G + G IY ++ S +
Sbjct: 556 ATDDLDFR-HHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELG 614
Query: 169 RPAIWIDTGIHSREWVTQASGVWFAKKITQDY--GQDAAFTAILDTLDIFLEIVTNPDGF 226
P GIH E + + + + + ++Y G + + DT I L NPDG+
Sbjct: 615 EPEFRYTAGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDT-RIHLVPSLNPDGY 673
Query: 227 AFTHSTNRMWRKTRSHTAGSLCIGVDPNRNW-------DAGFGLSGASSN---------- 269
+ G+ +G+ + D L GA
Sbjct: 674 EVAAQMGSEF--------GNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNN 725
Query: 270 --PCSETYHGKFANSEVEVKSIVDFVKDHGNIKAFISIHSYSQLLMYPYGYKTEPVPDQ 326
P E Y A EV++I+ +++ + + +++ +L+ YPY P +Q
Sbjct: 726 NLPIPERYLSPDATVSTEVRAIIAWMEKNPFVLG-ANLNGGERLVSYPYDMARTPTQEQ 783
>gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo
sapiens]
Length = 458
Score = 30.8 bits (68), Expect = 2.4
Identities = 31/143 (21%), Positives = 60/143 (41%), Gaps = 11/143 (7%)
Query: 122 YHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGS----KRPAIWIDTG 177
+H +++ L + E P + IG + EGR +YVL+FS P +
Sbjct: 25 HHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGN 84
Query: 178 IHSREWVTQASGVWFAKKITQDY-GQDAAFTAILDTLDIFLEIVTNPDGF--AFTHSTNR 234
+H E + + + ++ + +++ ++ ++ I + NPDG+ A N+
Sbjct: 85 MHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGPNK 144
Query: 235 MWRKTRSHTAGSLCIGVDPNRNW 257
+ A GVD NRN+
Sbjct: 145 PGYLVGRNNAN----GVDLNRNF 163
>gi|53832021 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 30.4 bits (67), Expect = 3.1
Identities = 36/154 (23%), Positives = 60/154 (38%), Gaps = 11/154 (7%)
Query: 122 YHTLEEIYDFLDLLVAENPHLVSKIQ-IGNTYEGRPIYVLKFSTGGSKR----PAIWIDT 176
YH E + FL VA+N V+ + IG + +GR ++VL + P
Sbjct: 22 YHRQEGMEAFLKT-VAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
Query: 177 GIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMW 236
+H E V + + + G+D T ++++ I + NPDGF + +
Sbjct: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
Query: 237 RKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNP 270
R + D NRN+ F + S P
Sbjct: 141 SIGRENYN-----QYDLNRNFPDAFEYNNVSRQP 169
>gi|38327526 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 30.4 bits (67), Expect = 3.1
Identities = 36/154 (23%), Positives = 60/154 (38%), Gaps = 11/154 (7%)
Query: 122 YHTLEEIYDFLDLLVAENPHLVSKIQ-IGNTYEGRPIYVLKFSTGGSKR----PAIWIDT 176
YH E + FL VA+N V+ + IG + +GR ++VL + P
Sbjct: 22 YHRQEGMEAFLKT-VAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
Query: 177 GIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMW 236
+H E V + + + G+D T ++++ I + NPDGF + +
Sbjct: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
Query: 237 RKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNP 270
R + D NRN+ F + S P
Sbjct: 141 SIGRENYN-----QYDLNRNFPDAFEYNNVSRQP 169
>gi|6631081 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 30.4 bits (67), Expect = 3.1
Identities = 36/154 (23%), Positives = 60/154 (38%), Gaps = 11/154 (7%)
Query: 122 YHTLEEIYDFLDLLVAENPHLVSKIQ-IGNTYEGRPIYVLKFSTGGSKR----PAIWIDT 176
YH E + FL VA+N V+ + IG + +GR ++VL + P
Sbjct: 22 YHRQEGMEAFLKT-VAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
Query: 177 GIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMW 236
+H E V + + + G+D T ++++ I + NPDGF + +
Sbjct: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
Query: 237 RKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNP 270
R + D NRN+ F + S P
Sbjct: 141 SIGRENYN-----QYDLNRNFPDAFEYNNVSRQP 169
>gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]
Length = 734
Score = 30.4 bits (67), Expect = 3.1
Identities = 24/136 (17%), Positives = 59/136 (43%), Gaps = 6/136 (4%)
Query: 100 EQEQMFAFRSRARSTDTFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYV 159
+ +F + S+D ++ +H + + + + + P++ IG +Y+G +YV
Sbjct: 278 DPNDLFLEAPASGSSDPLDFQ-HHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYV 336
Query: 160 LKFSTGGSK----RPAIWIDTGIHSREWVTQASGVWFAKKITQDYGQ-DAAFTAILDTLD 214
++ S + P + G+H E + + + + + ++ + + T +L +
Sbjct: 337 MEMSDKPGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMR 396
Query: 215 IFLEIVTNPDGFAFTH 230
I L NPDG+ +
Sbjct: 397 IHLLPSMNPDGYEIAY 412
>gi|31542244 leucine rich repeat and fibronectin type III domain
containing 5 [Homo sapiens]
Length = 719
Score = 29.6 bits (65), Expect = 5.3
Identities = 19/81 (23%), Positives = 36/81 (44%)
Query: 321 EPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQASGSTIDWTYSQGIKYSFTFE 380
EP P ++ +K+ +S TK + I+ A +S + + + + + I F+
Sbjct: 389 EPDPGSSDISTSTKSGSNTSSSNGDTKLSQDKIVVAEATSSTALLKFNFQRNIPGIRMFQ 448
Query: 381 LRDTGRYGFLLPASQIIPTAK 401
++ G Y L I PT+K
Sbjct: 449 IQYNGTYDDTLVYRMIPPTSK 469
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,602,195
Number of Sequences: 37866
Number of extensions: 667533
Number of successful extensions: 1574
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1530
Number of HSP's gapped (non-prelim): 34
length of query: 419
length of database: 18,247,518
effective HSP length: 105
effective length of query: 314
effective length of database: 14,271,588
effective search space: 4481278632
effective search space used: 4481278632
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.