Search of human proteins with 4502547

Search of human proteins with 4502547

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4502547 calcitonin receptor [Homo sapiens]
         (474 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502547 calcitonin receptor [Homo sapiens]                        1001   0.0  
gi|5031621 calcitonin receptor-like [Homo sapiens]                    556   e-158
gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]    237   2e-62
gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]    220   2e-57
gi|32307159 corticotropin releasing hormone receptor 2 [Homo sap...   218   9e-57
gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]   210   3e-54
gi|19923245 corticotropin releasing hormone receptor 1 isoform 2...   199   5e-51
gi|29171759 adenylate cyclase activating polypeptide 1 (pituitar...   198   1e-50
gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]          195   9e-50
gi|223717978 corticotropin releasing hormone receptor 1 isoform ...   187   1e-47
gi|114205383 secretin receptor precursor [Homo sapiens]               187   2e-47
gi|4503947 glucagon receptor [Homo sapiens]                           186   4e-47
gi|223717971 corticotropin releasing hormone receptor 1 isoform ...   184   2e-46
gi|4758438 glucagon-like peptide 2 receptor precursor [Homo sapi...   180   3e-45
gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]     177   2e-44
gi|223717985 corticotropin releasing hormone receptor 1 isoform ...   170   2e-42
gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]   160   2e-39
gi|58530851 growth hormone releasing hormone receptor isoform a ...   160   3e-39
gi|58530853 growth hormone releasing hormone receptor isoform b ...   109   5e-24
gi|45433552 G protein-coupled receptor 133 [Homo sapiens]             109   6e-24
gi|240120161 G protein-coupled receptor 144 [Homo sapiens]             87   3e-17
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]           87   4e-17
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]           87   4e-17
gi|163792198 latrophilin 3 precursor [Homo sapiens]                    84   4e-16
gi|6912464 latrophilin 2 precursor [Homo sapiens]                      83   5e-16
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s...    81   2e-15
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [...    76   6e-14
gi|40807489 egf-like module containing, mucin-like, hormone rece...    76   6e-14
gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]            75   1e-13
gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]            75   1e-13

>gi|4502547 calcitonin receptor [Homo sapiens]
          Length = 474

 Score = 1001 bits (2587), Expect = 0.0
 Identities = 474/474 (100%), Positives = 474/474 (100%)

Query: 1   MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVGRKKMMDAQYKCYDRMQ 60
           MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVGRKKMMDAQYKCYDRMQ
Sbjct: 1   MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVGRKKMMDAQYKCYDRMQ 60

Query: 61  QLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFK 120
           QLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFK
Sbjct: 61  QLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFK 120

Query: 121 HPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQR 180
           HPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQR
Sbjct: 121 HPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQR 180

Query: 181 VTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCE 240
           VTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCE
Sbjct: 181 VTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCE 240

Query: 241 GIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLLYI 300
           GIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLLYI
Sbjct: 241 GIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLLYI 300

Query: 301 IHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFP 360
           IHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFP
Sbjct: 301 IHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFP 360

Query: 361 WRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRR 420
           WRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRR
Sbjct: 361 WRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRR 420

Query: 421 PSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQESSA 474
           PSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQESSA
Sbjct: 421 PSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQESSA 474


>gi|5031621 calcitonin receptor-like [Homo sapiens]
          Length = 461

 Score =  556 bits (1434), Expect = e-158
 Identities = 257/445 (57%), Positives = 321/445 (72%), Gaps = 9/445 (2%)

Query: 8   RCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYV---VGRKKMMDAQYKCYDRMQQLPA 64
           +C   FL+L      LP F       +E  P   +   V R K+M AQY+CY ++ Q P 
Sbjct: 4   KCTLYFLVL------LPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECYQKIMQDPI 57

Query: 65  YQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFKHPEN 124
            Q EG YCNRTWDGWLCW+D  AG  S Q CPDYF DFDPSEKVTK CD+ G WF+HP +
Sbjct: 58  QQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPAS 117

Query: 125 NRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRVTLH 184
           NRTW+NYT CN  T EK+K A  L+YL I+GH LSI +L+ISLGIF +F+SL CQR+TLH
Sbjct: 118 NRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLH 177

Query: 185 KNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEGIYL 244
           KN+F +++ NS++ IIHL  V  N  LV  +PVSCK+  F H Y+M CNYFWMLCEGIYL
Sbjct: 178 KNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYL 237

Query: 245 HTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLLYIIHGP 304
           HTLIVVAVF EKQ L WYY LGWGFPL+P  IHAI R++Y+NDNCW+S +THLLYIIHGP
Sbjct: 238 HTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLLYIIHGP 297

Query: 305 VMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFPWRPS 364
           + AAL+VN FFLLNIVRVL+TK++ TH+AES++Y+KAV+AT+ILVPLLGI+FV+ PWRP 
Sbjct: 298 ICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPE 357

Query: 365 NKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRRPSNR 424
            K+  ++YDY+MH L+HFQG  V+TI+CF N EVQ  ++R W Q+KIQ+   +    + R
Sbjct: 358 GKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSFSNSEALR 417

Query: 425 SARAAAAAAEAGDIPIYICHQELRN 449
           SA    +    G    + C  E  N
Sbjct: 418 SASYTVSTISDGPGYSHDCPSEHLN 442


>gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]
          Length = 593

 Score =  237 bits (604), Expect = 2e-62
 Identities = 126/375 (33%), Positives = 196/375 (52%), Gaps = 32/375 (8%)

Query: 69  GPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFKHPENNRTW 128
           G  C   WD  LCW     G +    CPDY  DF+      + CD  G W   P +NRTW
Sbjct: 105 GRPCLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTW 164

Query: 129 SNYTMCNAFTPEKLKNAYVLYYLAI---VGHSLSIFTLVISLGIFVFFRSLGCQRVTLHK 185
           +NY+ C  F   + +   V   L +   VG+S+S+ +L +++ I  +FR L C R  +H 
Sbjct: 165 ANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHM 224

Query: 186 NMFLTYILNSMIIIIH-----------------------LVEVVPNGELVRRDPVSCKIL 222
           ++FL+++L ++ I +                        + +  P           C++ 
Sbjct: 225 HLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVA 284

Query: 223 HFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRA 282
             F  Y +A NY+W+L EG+YLH+LI +A F+EK+ L  + + GWG P V   +    RA
Sbjct: 285 VTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRA 344

Query: 283 VYFNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAE---SHMYL 339
              N  CW     +  +II  P++A++V+NF   +NIVRVL TK+RET+         Y 
Sbjct: 345 TLANTGCWDLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYR 404

Query: 340 KAVKATMILVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLI---HFQGFFVATIYCFCNN 396
           K +K+T++L+PL G+ ++VF   P  ++ G ++   MH  +    FQGFFVA IYCFCN 
Sbjct: 405 KLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNG 464

Query: 397 EVQTTVKRQWAQFKI 411
           EVQ  +K+ W+++ +
Sbjct: 465 EVQAEIKKSWSRWTL 479


>gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]
          Length = 550

 Score =  220 bits (560), Expect = 2e-57
 Identities = 131/398 (32%), Positives = 204/398 (51%), Gaps = 38/398 (9%)

Query: 66  QGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFKHPENN 125
           +GEG  C   WDG +CW     G +S   CP Y  DF+      ++C+  G W      N
Sbjct: 58  EGEGN-CFPEWDGLICWPRGTVGKISAVPCPPYIYDFNHKGVAFRHCNPNGTWDFMHSLN 116

Query: 126 RTWSNYTMCNAFTPEKL---KNAYV--LYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQR 180
           +TW+NY+ C  F    +   K  +   LY +  VG+S+S  +L +++ I  +FR L C R
Sbjct: 117 KTWANYSDCLRFLQPDISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTR 176

Query: 181 VTLHKNMFLTYILNSMIIII-------HLVEVVPNGELVRRDP--------------VSC 219
             +H ++F++++L +  I +       H+        +++ DP              + C
Sbjct: 177 NYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGC 236

Query: 220 KILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAI 279
           KI      Y +A NY+W+L EG+YLH LI VA F++ + L  + L+GWGFP       A+
Sbjct: 237 KIAVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAV 296

Query: 280 TRAVYFNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESH--- 336
            RA   +  CW      + +I   P++AA+ +NF   LN VRVL TK+ ET+ A  H   
Sbjct: 297 ARATLADARCWELSAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETN-AVGHDTR 355

Query: 337 -MYLKAVKATMILVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLI---HFQGFFVATIYC 392
             Y K  K+T++LV + G+ ++VF   P +   G  ++  MH  +    FQGFFV+ IYC
Sbjct: 356 KQYRKLAKSTLVLVLVFGVHYIVFVCLP-HSFTGLGWEIRMHCELFFNSFQGFFVSIIYC 414

Query: 393 FCNNEVQTTVKRQWAQFKIQWNQRWGRRPSNRSARAAA 430
           +CN EVQ  VK+ W+++ +  +  W R P   S R  +
Sbjct: 415 YCNGEVQAEVKKMWSRWNLSVD--WKRTPPCGSRRCGS 450


>gi|32307159 corticotropin releasing hormone receptor 2 [Homo
           sapiens]
          Length = 411

 Score =  218 bits (555), Expect = 9e-57
 Identities = 129/361 (35%), Positives = 193/361 (53%), Gaps = 24/361 (6%)

Query: 63  PAYQGEGPY--CNRTWDG-WLCWDDTPAGVLSYQFCPDYFPD--FDPSEKVTKYCDEKGV 117
           P    EGPY  CN T D    CW  + AG L  + CP+YF    ++ +    + C E G 
Sbjct: 29  PPLDPEGPYSYCNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGT 88

Query: 118 WFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIV----GHSLSIFTLVISLGIFVFF 173
           W           NY+ C     +K +   + Y +A+V    GH +S+  LV +  +F+  
Sbjct: 89  WASK-------INYSQCEPILDDKQRKYDLHYRIALVVNYLGHCVSVAALVAAFLLFLAL 141

Query: 174 RSLGCQRVTLHKNMFLTYIL-NSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMAC 232
           RS+ C R  +H N+  T+IL N M  ++ LV+     E+   + V C+ +     Y +  
Sbjct: 142 RSIRCLRNVIHWNLITTFILRNVMWFLLQLVD----HEVHESNEVWCRCITTIFNYFVVT 197

Query: 233 NYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLS 292
           N+FWM  EG YLHT IV+   TE+ R   +  +GW  P       AI +  Y N+ CW  
Sbjct: 198 NFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQCWFG 257

Query: 293 VETHLL--YIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVP 350
            E   L  YI  GP++  L++NF FL NIVR+L+TK+R +  +E+  Y KAVKAT++L+P
Sbjct: 258 KEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLP 317

Query: 351 LLGIQFVVFPWRPSNKMLGKI-YDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQF 409
           LLGI +++F   P    L +I + Y    L  FQGFFV+  YCF N EV++ V+++W ++
Sbjct: 318 LLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYCFFNGEVRSAVRKRWHRW 377

Query: 410 K 410
           +
Sbjct: 378 Q 378


>gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]
          Length = 457

 Score =  210 bits (534), Expect = 3e-54
 Identities = 121/405 (29%), Positives = 217/405 (53%), Gaps = 34/405 (8%)

Query: 47  KMMDAQYK-CYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPS 105
           +M++ Q+K C +  Q     + E   C++ WD   CW  TP G +    CP  F  F   
Sbjct: 41  QMIEVQHKQCLEEAQ----LENETIGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSI 96

Query: 106 E--KVTKYCDEKGVWFKHPENNRTWSNYTMCNAFTPE--KLKNAYVLYYLAI-----VGH 156
           +   V++ C ++G     P        Y +      +   L     ++Y ++     +G+
Sbjct: 97  QGRNVSRSCTDEGWTHLEP------GPYPIACGLDDKAASLDEQQTMFYGSVKTGYTIGY 150

Query: 157 SLSIFTLVISLGIFVFFRSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVR--R 214
            LS+ TL+++  I   FR L C R  +H ++F+++IL +  + I  + +  +GE  +   
Sbjct: 151 GLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQCSE 210

Query: 215 DPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPT 274
             V CK    F QY +  N+FW+L EG+YL+TL+ V+ F+E++    Y L+GWG P   T
Sbjct: 211 GSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFT 270

Query: 275 TIHAITRAVYFNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMR--ETHE 332
            +  I R  + +  CW ++ + L +II GP++ +++VNF   + I+R+L+ K+R  +  +
Sbjct: 271 MVWTIARIHFEDYGCWDTINSSLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRK 330

Query: 333 AESHMYLKAVKATMILVPLLGIQFVVFPWRPSN--KMLGKIYDYVMHSLIHFQGFFVATI 390
           ++S  Y +  ++T++L+PL G+ +++F + P N    +  +++ V+ S   FQGF VA +
Sbjct: 331 SDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMVFELVVGS---FQGFVVAIL 387

Query: 391 YCFCNNEVQTTVKRQWAQFKIQ----WNQRWGRRPSNRSARAAAA 431
           YCF N EVQ  ++R+W ++ +Q    WN ++ R PS  S  A  +
Sbjct: 388 YCFLNGEVQAELRRKWRRWHLQGVLGWNPKY-RHPSGGSNGATCS 431


>gi|19923245 corticotropin releasing hormone receptor 1 isoform 2
           [Homo sapiens]
          Length = 415

 Score =  199 bits (506), Expect = 5e-51
 Identities = 119/372 (31%), Positives = 196/372 (52%), Gaps = 28/372 (7%)

Query: 69  GPYCNRTWDG-WLCWDDTPAGVLSYQFCPDYFPD--FDPSEKVTKYCDEKGVWFKHPENN 125
           G  CN + D    CW  +PAG L  + CP +F    ++ +    + C   G W       
Sbjct: 41  GLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARV--- 97

Query: 126 RTWSNYTMCNAFTPEKLKNAYVLYYLAIV----GHSLSIFTLVISLGIFVFFRSLGCQRV 181
               NY+ C     E+ K + V Y++A++    GH +S+  L+++  +F+  RS+ C R 
Sbjct: 98  ----NYSECQEILNEE-KKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRN 152

Query: 182 TLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEG 241
            +H N+   +IL +    +  V++  + E+ + +   C+++   + Y    N+FWM  EG
Sbjct: 153 IIHWNLISAFILRNATWFV--VQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEG 210

Query: 242 IYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLL--Y 299
            YLHT IV+   T++ R   +  +GWG P       AI +  Y N+ CW      +   Y
Sbjct: 211 CYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDY 270

Query: 300 IIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVF 359
           I  GP++  L++NF FL NIVR+L+TK+R +  +E+  Y KAVKAT++L+PLLGI +++F
Sbjct: 271 IYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLF 330

Query: 360 PWRPSNKMLGK-IYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWG 418
              P    + + ++ Y    L  FQGFFV+  YCF N+EV++ ++++W         RW 
Sbjct: 331 FVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRW--------HRWQ 382

Query: 419 RRPSNRSARAAA 430
            + S R+  A A
Sbjct: 383 DKHSIRARVARA 394


>gi|29171759 adenylate cyclase activating polypeptide 1 (pituitary)
           receptor type I precursor [Homo sapiens]
          Length = 468

 Score =  198 bits (503), Expect = 1e-50
 Identities = 119/399 (29%), Positives = 192/399 (48%), Gaps = 48/399 (12%)

Query: 52  QYKCYDRMQ---QLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEK- 107
           Q  C +++Q   +L  +    P C   WD   CW     G +    CP+ F  F+P +  
Sbjct: 31  QAMCLEKIQRANELMGFNDSSPGCPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPDQVW 90

Query: 108 -----------------------VTKYCDEKGVWFKHPENNRTWSNYTMCNAFTPEKLKN 144
                                  V++ C E G     P        +  C     E    
Sbjct: 91  ETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPHY------FDACGFDEYESETG 144

Query: 145 AYVLYYLAI-----VGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKNMFLTYILNSMIII 199
               YYL++     VG+S S+ TL  ++ I   FR L C R  +H N+F++++L ++ + 
Sbjct: 145 DQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVF 204

Query: 200 IH--LVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQ 257
           I   ++    +        V CK +  F  Y +  NYFW+  EG+YL TL+V   F E++
Sbjct: 205 IKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERR 264

Query: 258 RLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCW-LSVETHLLYIIHGPVMAALVVNFFFL 316
              WY ++GWG P V  T+ A  R  + +  CW ++  T L ++I GPV+ +++VNF   
Sbjct: 265 YFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLF 324

Query: 317 LNIVRVLVTKMRETHEA--ESHMYLKAVKATMILVPLLGIQFVVFPWRPSN--KMLGKIY 372
           + I+ +LV K++       ES +YL+  ++T++L+PL GI + VF + P N  K    ++
Sbjct: 325 IGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVF 384

Query: 373 DYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKI 411
           +  + S   FQGF VA +YCF N EVQ  +KR+W  +K+
Sbjct: 385 ELGLGS---FQGFVVAVLYCFLNGEVQAEIKRKWRSWKV 420


>gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]
          Length = 463

 Score =  195 bits (495), Expect = 9e-50
 Identities = 109/365 (29%), Positives = 188/365 (51%), Gaps = 25/365 (6%)

Query: 71  YCNRTWDGWLCWDDTPAGVLSYQFCPDYFP--DFDPSEKVTKYCDEKGVWFKHPENNRTW 128
           +CNRT+D + CW D   G      CP Y P     P   V ++C  +G+W +   ++  W
Sbjct: 61  FCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPW 120

Query: 129 SNYTMCNAF------TPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRVT 182
            + + C         +PE+      LY +  VG++LS   LVI+  I + FR L C R  
Sbjct: 121 RDLSECEESKRGERSSPEE--QLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNY 178

Query: 183 LHKNMFLTYILNSMIIIIHLVEVVP-----------NGELVRRDPVSCKILHFFHQYMMA 231
           +H N+F ++IL ++ + I    +             +G L  +D +SC+++    QY +A
Sbjct: 179 IHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVA 238

Query: 232 CNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWL 291
            NY+W+L EG+YL+TL+  +V +E+   R Y  +GWG PL+      I + +Y ++ CW 
Sbjct: 239 ANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWT 298

Query: 292 -SVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVP 350
            +   +   II  P++ A+ VNF   + ++ ++V+K++     ++ +  +  K+T+ L+P
Sbjct: 299 RNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIP 358

Query: 351 LLGIQFVVFPWRPSNKMLGK---IYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWA 407
           LLG   V+F +       G    I  +   S   FQG  VA +YCF NNEVQ   ++ W 
Sbjct: 359 LLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWE 418

Query: 408 QFKIQ 412
           +++++
Sbjct: 419 RWRLE 423


>gi|223717978 corticotropin releasing hormone receptor 1 isoform 3
           [Homo sapiens]
          Length = 375

 Score =  187 bits (476), Expect = 1e-47
 Identities = 105/316 (33%), Positives = 176/316 (55%), Gaps = 21/316 (6%)

Query: 125 NRTWS---NYTMCNAFTPEKLKNAYVLYYLAIV----GHSLSIFTLVISLGIFVFFRSLG 177
           N +W+   NY+ C     E+ K + V Y++A++    GH +S+  L+++  +F+  RS+ 
Sbjct: 50  NGSWAARVNYSECQEILNEE-KKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIR 108

Query: 178 CQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWM 237
           C R  +H N+   +IL +    +  V++  + E+ + +   C+++   + Y    N+FWM
Sbjct: 109 CLRNIIHWNLISAFILRNATWFV--VQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWM 166

Query: 238 LCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHL 297
             EG YLHT IV+   T++ R   +  +GWG P       AI +  Y N+ CW      +
Sbjct: 167 FGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGV 226

Query: 298 L--YIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQ 355
              YI  GP++  L++NF FL NIVR+L+TK+R +  +E+  Y KAVKAT++L+PLLGI 
Sbjct: 227 YTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGIT 286

Query: 356 FVVFPWRPSNKMLGK-IYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWN 414
           +++F   P    + + ++ Y    L  FQGFFV+  YCF N+EV++ ++++W        
Sbjct: 287 YMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRW-------- 338

Query: 415 QRWGRRPSNRSARAAA 430
            RW  + S R+  A A
Sbjct: 339 HRWQDKHSIRARVARA 354


>gi|114205383 secretin receptor precursor [Homo sapiens]
          Length = 440

 Score =  187 bits (475), Expect = 2e-47
 Identities = 108/351 (30%), Positives = 187/351 (53%), Gaps = 13/351 (3%)

Query: 70  PYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSE-KVTKYCDEKGVWFKHPENNRTW 128
           P C   WD   CW  +  G +    CP +          + + C + G     P  N   
Sbjct: 64  PGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDGWSETFPRPNLAC 123

Query: 129 SNYTMCNAFTPEKLKNAYVLYYLAI--VGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKN 186
                 N  + EK +++Y+L    +  VG+S S+  L+++LGI   FR L C R  +H +
Sbjct: 124 G--VNVNDSSNEK-RHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMH 180

Query: 187 MFLTYILNSMIIIIHLVEVVPNGELVRRDP--VSCKILHFFHQYMMACNYFWMLCEGIYL 244
           +F+++IL ++   I    +  + ++   D     CK++    QY +  NY W+L EG+YL
Sbjct: 181 LFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYL 240

Query: 245 HTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCW-LSVETHLLYIIHG 303
           HTL+ ++ F+E++ L+ +   GWG P +   + AI R    +  CW ++    + +II G
Sbjct: 241 HTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASIWWIIRG 300

Query: 304 PVMAALVVNFFFLLNIVRVLVTKMR--ETHEAESHMYLKAVKATMILVPLLGIQFVVFPW 361
           PV+ ++++NF   +NI+R+L+ K+R  ET   E   Y +  ++T++L+PL GI ++VF +
Sbjct: 301 PVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAF 360

Query: 362 RPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQ 412
            P + M  +I  +   +L  FQG  VA +YCF N EVQ  V+++W Q+ ++
Sbjct: 361 SPEDAM--EIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLR 409


>gi|4503947 glucagon receptor [Homo sapiens]
          Length = 477

 Score =  186 bits (472), Expect = 4e-47
 Identities = 115/377 (30%), Positives = 190/377 (50%), Gaps = 38/377 (10%)

Query: 72  CNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEK--VTKYCDEKGVWFKHPENNRTWS 129
           CNRT+D + CW DTPA   +   CP Y P     +   V K C   G W + P   + W 
Sbjct: 58  CNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRG-QPWR 116

Query: 130 NYTMCNAFTPE--------KLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRV 181
           + + C     E        K+ +++ + Y   VG+SLS+  L+++L I      L C R 
Sbjct: 117 DASQCQMDGEEIEVQKEVAKMYSSFQVMYT--VGYSLSLGALLLALAILGGLSKLHCTRN 174

Query: 182 TLHKNMFLTYIL--NSMIIIIHLVEVVPNGELVRRDPVS----------CKILHFFHQYM 229
            +H N+F +++L  +S+++I  L+    + ++     VS          C++   F QY 
Sbjct: 175 AIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYG 234

Query: 230 MACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNC 289
           +  NY W+L EG+YLH L+ +A   E+     Y  +GWG P++     A+ + ++ N  C
Sbjct: 235 IVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQC 294

Query: 290 WLSVET-HLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMIL 348
           W S +     +I+  PV  A+++NFF  + IV++LV K+R      +    +  K+T+ L
Sbjct: 295 WTSNDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTL 354

Query: 349 VPLLGIQFVVFPWRPSNKMLGKI------YDYVMHSLIHFQGFFVATIYCFCNNEVQTTV 402
           +PLLG+  VVF +       G +      +D  + S   FQG  VA +YCF N EVQ+ +
Sbjct: 355 IPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSS---FQGLLVAVLYCFLNKEVQSEL 411

Query: 403 KRQWAQF---KIQWNQR 416
           +R+W ++   K+ W +R
Sbjct: 412 RRRWHRWRLGKVLWEER 428


>gi|223717971 corticotropin releasing hormone receptor 1 isoform 1
           [Homo sapiens]
          Length = 444

 Score =  184 bits (466), Expect = 2e-46
 Identities = 119/401 (29%), Positives = 196/401 (48%), Gaps = 57/401 (14%)

Query: 69  GPYCNRTWDG-WLCWDDTPAGVLSYQFCPDYFPD--FDPSEKVTKYCDEKGVWFKHPENN 125
           G  CN + D    CW  +PAG L  + CP +F    ++ +    + C   G W       
Sbjct: 41  GLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARV--- 97

Query: 126 RTWSNYTMCNAFTPEKLKNAYVLYYLAIV----GHSLSIFTLVISLGIFVFFR------- 174
               NY+ C     E+ K + V Y++A++    GH +S+  L+++  +F+  R       
Sbjct: 98  ----NYSECQEILNEE-KKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRPGCTHWG 152

Query: 175 ----------------------SLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELV 212
                                 S+ C R  +H N+   +IL +    +  V++  + E+ 
Sbjct: 153 DQADGALEVGAPWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFV--VQLTMSPEVH 210

Query: 213 RRDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLV 272
           + +   C+++   + Y    N+FWM  EG YLHT IV+   T++ R   +  +GWG P  
Sbjct: 211 QSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFP 270

Query: 273 PTTIHAITRAVYFNDNCWLSVETHLL--YIIHGPVMAALVVNFFFLLNIVRVLVTKMRET 330
                AI +  Y N+ CW      +   YI  GP++  L++NF FL NIVR+L+TK+R +
Sbjct: 271 IIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRAS 330

Query: 331 HEAESHMYLKAVKATMILVPLLGIQFVVFPWRPSNKMLGK-IYDYVMHSLIHFQGFFVAT 389
             +E+  Y KAVKAT++L+PLLGI +++F   P    + + ++ Y    L  FQGFFV+ 
Sbjct: 331 TTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSV 390

Query: 390 IYCFCNNEVQTTVKRQWAQFKIQWNQRWGRRPSNRSARAAA 430
            YCF N+EV++ ++++W         RW  + S R+  A A
Sbjct: 391 FYCFLNSEVRSAIRKRW--------HRWQDKHSIRARVARA 423


>gi|4758438 glucagon-like peptide 2 receptor precursor [Homo
           sapiens]
          Length = 553

 Score =  180 bits (456), Expect = 3e-45
 Identities = 113/384 (29%), Positives = 193/384 (50%), Gaps = 31/384 (8%)

Query: 51  AQYK--CYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDF--DPSE 106
           AQYK  C   + + P+    G +CN T+D ++CW  +  G +S   CP Y P +  + S 
Sbjct: 77  AQYKQACLRDLLKEPS----GIFCNGTFDQYVCWPHSSPGNVSVP-CPSYLPWWSEESSG 131

Query: 107 KVTKYCDEKGVWFKHPENNRTWSNYTMCN---AFTPEKLKNAYV--LYYLAIVGHSLSIF 161
           +  ++C  +G W         W + + C+   +F     + A +  L  +  VG+S S+ 
Sbjct: 132 RAYRHCLAQGTWQTIENATDIWQDDSECSENHSFKQNVDRYALLSTLQLMYTVGYSFSLI 191

Query: 162 TLVISLGIFVFFRSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRD------ 215
           +L ++L + +F R L C R  +H N+F ++IL ++ +++  V V  N    R D      
Sbjct: 192 SLFLALTLLLFLRKLHCTRNYIHMNLFASFILRTLAVLVKDV-VFYNSYSKRPDNENGWM 250

Query: 216 ------PVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGF 269
                   SC+ +     Y +  NY W+L EG+YLHTL+   V  E++    Y LLGW F
Sbjct: 251 SYLSEMSTSCRSVQVLLHYFVGANYLWLLVEGLYLHTLLEPTVLPERRLWPRYLLLGWAF 310

Query: 270 PLVPTTIHAITRAVYFNDNCW-LSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMR 328
           P++        RA   N  CW  +    + +II GP+M  + VNFF  L I+++L++K++
Sbjct: 311 PVLFVVPWGFARAHLENTGCWTTNGNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLK 370

Query: 329 ETHEAESHMYLKAVKATMILVPLLGIQFVVFPWRPSNKMLG---KIYDYVMHSLIHFQGF 385
                      +  K+T++L+PLLG+  ++F +   +++ G    I  ++  +L  F GF
Sbjct: 371 AHQMCFRDYKYRLAKSTLVLIPLLGVHEILFSFITDDQVEGFAKLIRLFIQLTLSSFHGF 430

Query: 386 FVATIYCFCNNEVQTTVKRQWAQF 409
            VA  Y F N EV+  +++ W +F
Sbjct: 431 LVALQYGFANGEVKAELRKYWVRF 454


>gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]
          Length = 466

 Score =  177 bits (448), Expect = 2e-44
 Identities = 117/396 (29%), Positives = 193/396 (48%), Gaps = 37/396 (9%)

Query: 69  GPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFP--DFDPSEKVTKYCDEKGVWFKHPENNR 126
           G  CN ++D ++CWD       +   CP Y P      +  V + C   G W        
Sbjct: 58  GLACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQW-------G 110

Query: 127 TWSNYTMCNAFTPEK----LKNAYVLYYLAI---VGHSLSIFTLVISLGIFVFFRSLGCQ 179
            W ++T C    PEK    L    +L  L +   VG+SLS+ TL+++L I   FR L C 
Sbjct: 111 LWRDHTQCE--NPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCT 168

Query: 180 RVTLHKNMFLTYILNSMIIIIHLVEVVPNGE--------LVRRDPVSCKILHFFHQYMMA 231
           R  +H N+F +++L +  I+     +   G         L  +   +C+      QY + 
Sbjct: 169 RNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVG 228

Query: 232 CNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWL 291
            NY W+L EG+YLH+L+V+   +E+   R+Y LLGWG P +      I R +Y N  CW 
Sbjct: 229 ANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWE 288

Query: 292 SVETHLL-YIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVP 350
             E   + +II  P++  +++NF   + I+ +L++K+R          L+  ++T+ LVP
Sbjct: 289 RNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVP 348

Query: 351 LLGIQFVVFPWRPSNKMLGKI------YDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKR 404
           LLG+  VVF      +  G +      ++  + S   FQGF V+ +YCF N EVQ+ ++R
Sbjct: 349 LLGVHEVVFAPVTEEQARGALRFAKLGFEIFLSS---FQGFLVSVLYCFINKEVQSEIRR 405

Query: 405 QWAQFKIQWN-QRWGRRPSNRSARAAAAAAEAGDIP 439
            W   +++ +     R+   R+ RA  + +  G++P
Sbjct: 406 GWHHCRLRRSLGEEQRQLPERAFRALPSGSGPGEVP 441


>gi|223717985 corticotropin releasing hormone receptor 1 isoform 4
           [Homo sapiens]
          Length = 401

 Score =  170 bits (431), Expect = 2e-42
 Identities = 109/371 (29%), Positives = 186/371 (50%), Gaps = 40/371 (10%)

Query: 69  GPYCNRTWDG-WLCWDDTPAGVLSYQFCPDYFPD--FDPSEKVTKYCDEKGVWFKHPENN 125
           G  CN + D    CW  +PAG L  + CP +F    ++ +    + C   G W       
Sbjct: 41  GLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARV--- 97

Query: 126 RTWSNYTMCNAFTPEKLKNAYVLYYLAIV----GHSLSIFTLVISLGIFVFFRSLGCQRV 181
               NY+ C     E+ K + V Y++A++    GH +S+  L+++  +F+  RS+ C R 
Sbjct: 98  ----NYSECQEILNEE-KKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRN 152

Query: 182 TLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEG 241
            +H N+   +IL +    +  V++  + E+ + +   C+++   + Y    N+FWM  EG
Sbjct: 153 IIHWNLISAFILRNATWFV--VQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEG 210

Query: 242 IYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLL--Y 299
            YLHT IV+   T++ R   +  +GWG P       AI +  Y N+ CW      +   Y
Sbjct: 211 CYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDY 270

Query: 300 IIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVF 359
           I  GP++  L++NF FL NIVR+L+TK+R +  +E+  Y KAVKAT++L+PLLGI +++F
Sbjct: 271 IYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLF 330

Query: 360 PWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGR 419
              P    + ++        I+F  F  +        +V++ ++++W         RW  
Sbjct: 331 FVNPGEDEVSRVV------FIYFNSFLESF-------QVRSAIRKRW--------HRWQD 369

Query: 420 RPSNRSARAAA 430
           + S R+  A A
Sbjct: 370 KHSIRARVARA 380


>gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]
          Length = 438

 Score =  160 bits (406), Expect = 2e-39
 Identities = 105/352 (29%), Positives = 176/352 (50%), Gaps = 30/352 (8%)

Query: 72  CNRTWDGWLCWDDTPAGVLSYQFCPDYFPDF-DPSEKVTKYCDEKGVWFKHPENNRTWSN 130
           C+  WD   CW     G      CP  F +F   +  ++K C   G W      + T+ +
Sbjct: 52  CSGVWDNITCWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDG-W------SETFPD 104

Query: 131 YT-MCNAFTPEKLKNAYVLYYLAI-----VGHSLSIFTLVISLGIFVFFRSLGCQRVTLH 184
           +   C    PE    + + +Y+ +     +G+S+S+ +L     I   FR L C R  +H
Sbjct: 105 FVDACGYSDPED--ESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIH 162

Query: 185 KNMFLTYILNSMIIIIHL-VEVVPNGELVRRDP----VSCKILHFFHQYMMACNYFWMLC 239
            N+FL++IL ++ +++   V    +G L   D     V CK+   F QY +  N+FW+L 
Sbjct: 163 LNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLV 222

Query: 240 EGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLL- 298
           EG+YLHTL+ VA+   ++    Y L+GWG P V        R    +  CW     H + 
Sbjct: 223 EGLYLHTLL-VAMLPPRRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGCW-DTNDHSVP 280

Query: 299 -YIIHGPVMAALVVNFFFLLNIVRVLVTKMR--ETHEAESHMYLKAVKATMILVPLLGIQ 355
            ++I  P++ +++VNF   ++I+R+L+ K+   +    +   Y +  K+T++L+PL G+ 
Sbjct: 281 WWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVH 340

Query: 356 FVVFPWRPSNKMLGKIYDYVMH-SLIHFQGFFVATIYCFCNNEVQTTVKRQW 406
           ++VF   P +  +   Y  +    L  FQG  VA +YCF N+EVQ  +KR+W
Sbjct: 341 YMVFAVFPIS--ISSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKW 390


>gi|58530851 growth hormone releasing hormone receptor isoform a
           precursor [Homo sapiens]
          Length = 423

 Score =  160 bits (404), Expect = 3e-39
 Identities = 107/346 (30%), Positives = 168/346 (48%), Gaps = 20/346 (5%)

Query: 72  CNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDP-SEKVTKYCDEKGVWFKHPENNRTWSN 130
           C  TWDG LCW    +G      CPD+F  F   S  V + C   G W      +  +  
Sbjct: 55  CPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITG-W------SEPFPP 107

Query: 131 YTMCNAFTPEKL--KNAY--VLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKN 186
           Y +      E L  + +Y   +  +  VGHS+SI  L +++ I V  R L C R  +H  
Sbjct: 108 YPVACPVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQ 167

Query: 187 MFLTYILNSMIIIIHLVEVVPNGEL--VRRDPVSCKILHFFHQYMMACNYFWMLCEGIYL 244
           +F T+IL +  + +    +  + +        V CK+      +    N+ W+L E +YL
Sbjct: 168 LFTTFILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYL 227

Query: 245 HTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCW-LSVETHLLYIIHG 303
           + L+     + ++   W  L GWG P++ T      +  + +  CW L   +   +II G
Sbjct: 228 NCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKG 287

Query: 304 PVMAALVVNFFFLLNIVRVLVTKMRETHEAESH---MYLKAVKATMILVPLLGIQFVVFP 360
           P++ ++ VNF   LNI+R+LV K+ E  +   H    Y +  K+T+ L+PL GI +++F 
Sbjct: 288 PIVLSVGVNFGLFLNIIRILVRKL-EPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFN 346

Query: 361 WRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQW 406
           + P N  LG I   +   L  FQGF VA +YCF N EV+T + R+W
Sbjct: 347 FLPDNAGLG-IRLPLELGLGSFQGFIVAILYCFLNQEVRTEISRKW 391


>gi|58530853 growth hormone releasing hormone receptor isoform b
           precursor [Homo sapiens]
          Length = 337

 Score =  109 bits (273), Expect = 5e-24
 Identities = 75/264 (28%), Positives = 122/264 (46%), Gaps = 15/264 (5%)

Query: 72  CNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDP-SEKVTKYCDEKGVWFKHPENNRTWSN 130
           C  TWDG LCW    +G      CPD+F  F   S  V + C   G W      +  +  
Sbjct: 55  CPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITG-W------SEPFPP 107

Query: 131 YTMCNAFTPEKL--KNAY--VLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKN 186
           Y +      E L  + +Y   +  +  VGHS+SI  L +++ I V  R L C R  +H  
Sbjct: 108 YPVACPVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQ 167

Query: 187 MFLTYILNSMIIIIHLVEVVPNGEL--VRRDPVSCKILHFFHQYMMACNYFWMLCEGIYL 244
           +F T+IL +  + +    +  + +        V CK+      +    N+ W+L E +YL
Sbjct: 168 LFTTFILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYL 227

Query: 245 HTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCW-LSVETHLLYIIHG 303
           + L+     + ++   W  L GWG P++ T      +  + +  CW L   +   +II G
Sbjct: 228 NCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKG 287

Query: 304 PVMAALVVNFFFLLNIVRVLVTKM 327
           P++ ++ VNF   LNI+R+LV K+
Sbjct: 288 PIVLSVGVNFGLFLNIIRILVRKL 311


>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
          Length = 874

 Score =  109 bits (272), Expect = 6e-24
 Identities = 80/330 (24%), Positives = 148/330 (44%), Gaps = 41/330 (12%)

Query: 105 SEKVTKYC------DEKGVWFKH----PENNRTWS--------NYTMCNAFTPEKLKNAY 146
           S +V  YC        +GVW  H       N T+S        N+ +     P +L   +
Sbjct: 503 SNRVFVYCAFLDFSSGEGVWSNHGCALTRGNLTYSVCRCTHLTNFAILMQVVPLELARGH 562

Query: 147 --VLYYLAIVGHSLSIFTLVISLGIFVFFRSLGC---QRVTLHKNMFLTYILNSMIIIIH 201
              L  ++ VG SLS+  LV +L  F    S+     QR  +H N+    ++  ++++I 
Sbjct: 563 QVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLIS 622

Query: 202 LVEVVPNGELVRRDP--VSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRL 259
                      R +P    C+++     Y     + WML EG++L+++++    +E  + 
Sbjct: 623 F----------RLEPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKH 672

Query: 260 RWYYLLGWGFPLVPTTIHAITRAVYF--NDNCWLSVETHLLYIIHGPVMAALVVNFFFLL 317
           R+YY +GWGFPL+   I        +  ++NCWLS+ +  ++    P +  +VVN   L+
Sbjct: 673 RYYYGMGWGFPLLICIISLSFAMDSYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGILI 732

Query: 318 NIVRVLVTKMRETHE--AESHMYLKAVKATMILVPLLGIQFVVFPWRPSNKMLGKIYDYV 375
            + RV+     + ++   +   +    KA  +L+P+LG  +V      +      ++ Y+
Sbjct: 733 AVTRVISQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNG--CAVVFQYM 790

Query: 376 MHSLIHFQGFFVATIYCFCNNEVQTTVKRQ 405
             +L   QG F+   +C  N+EV+   K +
Sbjct: 791 FATLNSLQGLFIFLFHCLLNSEVRAAFKHK 820


>gi|240120161 G protein-coupled receptor 144 [Homo sapiens]
          Length = 963

 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 70/273 (25%), Positives = 118/273 (43%), Gaps = 30/273 (10%)

Query: 147 VLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVV 206
           +L  L+ VG  +S   L  +  +F+       +R T+HKN  LT+ L S          +
Sbjct: 657 LLRTLSFVGCGVSFCALTTTFLLFLVAGVPKSERTTVHKN--LTFSLASA------EGFL 708

Query: 207 PNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLG 266
              E  + + V+C  +     ++    + WML EG+ L   +V         +R Y+  G
Sbjct: 709 MTSEWAKANEVACVAVTVAMHFLFLVAFSWMLVEGLLLWRKVVAVSMHPGPGMRLYHATG 768

Query: 267 WGFPLVPTTIHAITRAVYFND-----NCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVR 321
           WG   VP  I A+T A+  +D     +CWL+V T+ ++   GPV+  L  N   L  +V 
Sbjct: 769 WG---VPVGIVAVTLAMLPHDYVAPGHCWLNVHTNAIWAFVGPVLFVLTANTCILARVVM 825

Query: 322 VLVTKMRETHEAES----------HMYLKAVKATMILVPLLGIQFVVFPWRPSNKMLGKI 371
           + V+  R      S                VK  ++L+P+LG+ ++          L   
Sbjct: 826 ITVSSARRRARMLSPQPCLQQQIWTQIWATVKPVLVLLPVLGLTWLA----GILVHLSPA 881

Query: 372 YDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKR 404
           + Y    L   QG ++  +Y  CN EV++ ++R
Sbjct: 882 WAYAAVGLNSIQGLYIFLVYAACNEEVRSALQR 914


>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
          Length = 1474

 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 65/259 (25%), Positives = 116/259 (44%), Gaps = 14/259 (5%)

Query: 144  NAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKNMFLTYILNSMIIIIHLV 203
            N  +L  +  VG  +S+  L I +  F F R L   R T+HKN+ +   L  ++ ++ + 
Sbjct: 856  NELLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGID 915

Query: 204  EVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYY 263
            +         +  ++C I      Y     + W+  EG++L+ L+V    +E  R ++YY
Sbjct: 916  KT--------QYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYY 967

Query: 264  LLGWGFPLVPTTIHAIT--RAVYFNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVR 321
            L G+ FP +   I A    R+      CWL V+ + ++   GPV   +VVN  FL+  + 
Sbjct: 968  LGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMVTLH 1027

Query: 322  VLVTKMRETHEAESHM-YLKA-VKATMILVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSL 379
             ++          S +  +K+     + L+ LLG+ +  F     NK    +  Y+  + 
Sbjct: 1028 KMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTW-AFGLLFINKE-SVVMAYLFTTF 1085

Query: 380  IHFQGFFVATIYCFCNNEV 398
              FQG F+   +C    +V
Sbjct: 1086 NAFQGVFIFVFHCALQKKV 1104


>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
          Length = 1469

 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 65/259 (25%), Positives = 116/259 (44%), Gaps = 14/259 (5%)

Query: 144  NAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKNMFLTYILNSMIIIIHLV 203
            N  +L  +  VG  +S+  L I +  F F R L   R T+HKN+ +   L  ++ ++ + 
Sbjct: 851  NELLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGID 910

Query: 204  EVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYY 263
            +         +  ++C I      Y     + W+  EG++L+ L+V    +E  R ++YY
Sbjct: 911  KT--------QYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYY 962

Query: 264  LLGWGFPLVPTTIHAIT--RAVYFNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVR 321
            L G+ FP +   I A    R+      CWL V+ + ++   GPV   +VVN  FL+  + 
Sbjct: 963  LGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMVTLH 1022

Query: 322  VLVTKMRETHEAESHM-YLKA-VKATMILVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSL 379
             ++          S +  +K+     + L+ LLG+ +  F     NK    +  Y+  + 
Sbjct: 1023 KMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTW-AFGLLFINKE-SVVMAYLFTTF 1080

Query: 380  IHFQGFFVATIYCFCNNEV 398
              FQG F+   +C    +V
Sbjct: 1081 NAFQGVFIFVFHCALQKKV 1099


>gi|163792198 latrophilin 3 precursor [Homo sapiens]
          Length = 1469

 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 45/165 (27%), Positives = 82/165 (49%), Gaps = 10/165 (6%)

Query: 154  VGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVR 213
            VG  LS+  L+I +  F FFR L   R T+HKN+ ++  +  ++ +I +           
Sbjct: 883  VGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRT-------- 934

Query: 214  RDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFP-LV 272
              P++C +      +     + WM  EG+ L+ ++V    +E  R +++YL+G+G P L+
Sbjct: 935  DQPIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLVGYGMPALI 994

Query: 273  PTTIHAITRAVYFNDN-CWLSVETHLLYIIHGPVMAALVVNFFFL 316
                 A+    Y  D  CWL ++T+ ++   GP    +++N  FL
Sbjct: 995  VAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFL 1039


>gi|6912464 latrophilin 2 precursor [Homo sapiens]
          Length = 1403

 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 66/262 (25%), Positives = 124/262 (47%), Gaps = 24/262 (9%)

Query: 147  VLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVV 206
            +L  +  VG  +S+  L I +  F FFR L   R T+HKN+ +   +   I +I + +  
Sbjct: 833  LLTVITWVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDKT- 891

Query: 207  PNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLG 266
               +     P+   +LHFF     A    WM  EG+ L+ ++V    +E  R ++YY+ G
Sbjct: 892  ---KYAIACPIFAGLLHFFFLAAFA----WMCLEGVQLYLMLVEVFESEYSRKKYYYVAG 944

Query: 267  WGFPLVPTTIHAITRAVYFND-----NCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVR 321
            +   L P T+  ++ A+ +        CWL V+ + ++   GPV   +++N  FL+ I  
Sbjct: 945  Y---LFPATVVGVSAAIDYKSYGTEKACWLHVDNYFIWSFIGPVTFIILLNIIFLV-ITL 1000

Query: 322  VLVTKMRETHEAESHMYLKAVKATMI----LVPLLGIQFVVFPWRPSNKMLGKIYDYVMH 377
              + K   T + +S   L+ +K+ ++    L+ LLG+ +       + + +   Y + + 
Sbjct: 1001 CKMVKHSNTLKPDSSR-LENIKSWVLGAFALLCLLGLTWSFGLLFINEETIVMAYLFTIF 1059

Query: 378  SLIHFQGFFVATIYCFCNNEVQ 399
            +   FQG F+   +C    +V+
Sbjct: 1060 NA--FQGVFIFIFHCALQKKVR 1079


>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
            sapiens]
          Length = 3014

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 54/259 (20%), Positives = 121/259 (46%), Gaps = 17/259 (6%)

Query: 147  VLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVV 206
            ++ Y A+   SLS+  L+++  +    R L     ++HK++ +   L+ ++ +I + +  
Sbjct: 2470 IVTYAAV---SLSLAALLVAFVLLSLVRMLRSNLHSIHKHLAVALFLSQLVFVIGINQT- 2525

Query: 207  PNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLG 266
                    +P  C ++     Y+    + W L E ++++ ++      +   +R+YY++G
Sbjct: 2526 -------ENPFLCTVVAILLHYIYMSTFAWTLVESLHVYRMLTEVRNIDTGPMRFYYVVG 2578

Query: 267  WGFPLVPTTIH-AITRAVYFN-DNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLV 324
            WG P + T +   +    Y N D CWLS++  L++   GP+ A +++N   + +++   V
Sbjct: 2579 WGIPAIVTGLAVGLDPQGYGNPDFCWLSLQDTLIWSFAGPIGAVIIIN--TVTSVLSAKV 2636

Query: 325  TKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQG 384
            +  R+ H       +  ++   +L+ L+   +++     +   L   + Y+       QG
Sbjct: 2637 SCQRKHHYYGKKGIVSLLRTAFLLLLLISATWLLGLLAVNRDALS--FHYLFAIFSGLQG 2694

Query: 385  FFVATIYCFCNNEVQTTVK 403
             FV   +C  N EV+  +K
Sbjct: 2695 PFVLLFHCVLNQEVRKHLK 2713


>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [Homo
            sapiens]
          Length = 1584

 Score = 76.3 bits (186), Expect = 6e-14
 Identities = 67/257 (26%), Positives = 120/257 (46%), Gaps = 18/257 (7%)

Query: 153  IVGHSLSIFTLVISLGIFV-FFRSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGEL 211
            IVG  +S  TL++ + I+V  +R +  +R  +  N  L+ I ++ +I+I        G+ 
Sbjct: 952  IVGCGVSSLTLLMLVIIYVSVWRYIRSERSVILINFCLSIISSNALILI--------GQT 1003

Query: 212  VRRDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPL 271
              R+ V C ++  F  +    ++ W+L E    +  +   +     R R +  LGWG P 
Sbjct: 1004 QTRNKVVCTLVAAFLHFFFLSSFCWVLTEAWQSYMAVTGHLRNRLIRKR-FLCLGWGLPA 1062

Query: 272  VPTTIHA-ITRAVYFN--DNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMR 328
            +   I    T+A  ++  + CWLS+E  LLY   GP  A ++VN    + +   LV+K  
Sbjct: 1063 LVVAISVGFTKAKGYSTMNYCWLSLEGGLLYAFVGPAAAVVLVNMVIGILVFNKLVSKDG 1122

Query: 329  ETHEAESHMYLKAVKATMILVPLLGIQFV--VFPWRPSNKMLGKIYDYVMHSLIHFQGFF 386
             T +        ++ ++ +++PLL + ++  V         L +I   V  SL   +GF 
Sbjct: 1123 ITDKKLKERAGASLWSSCVVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSL---EGFV 1179

Query: 387  VATIYCFCNNEVQTTVK 403
            +  ++C    EVQ  VK
Sbjct: 1180 IVMVHCILRREVQDAVK 1196


>gi|40807489 egf-like module containing, mucin-like, hormone
           receptor-like sequence 1 [Homo sapiens]
          Length = 886

 Score = 76.3 bits (186), Expect = 6e-14
 Identities = 66/273 (24%), Positives = 122/273 (44%), Gaps = 29/273 (10%)

Query: 146 YVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKNMFLTYILNSMIII--IHLV 203
           + LY ++ VG  +S+  LV+++  F+  RS+      LH ++ +  +L   + +  IH  
Sbjct: 600 FSLYIISHVGIIISLVCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLLAKTLFLAGIHKT 659

Query: 204 EVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLI----VVAVFTEKQ-R 258
           +          + + C I+  F  Y+    +FWML E + L  ++    VV  F+ +  +
Sbjct: 660 D----------NKMGCAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIK 709

Query: 259 LRWYYLLGWGFPLVPTTIHAITRAVYF--NDNCWLSVETHLLYIIHGPVMAALVVNFFFL 316
           +      G+G P++   I A  +   +  ++ CWL+ ET  ++   GPV   +V+N   L
Sbjct: 710 MLHICAFGYGLPMLVVVISASVQPQGYGMHNRCWLNTETGFIWSFLGPVCTVIVINSLLL 769

Query: 317 ---LNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFV--VFPWRPSNKMLGKI 371
              L I+R  ++ +           L   KA   L  +LG  +V  +F   P    +  +
Sbjct: 770 TWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFAQLF-ILGCSWVLGIFQIGP----VAGV 824

Query: 372 YDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKR 404
             Y+   +   QG F+  I+C  N +V+   KR
Sbjct: 825 MAYLFTIINSLQGAFIFLIHCLLNGQVREEYKR 857


>gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]
          Length = 786

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 68/261 (26%), Positives = 118/261 (45%), Gaps = 19/261 (7%)

Query: 154 VGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVR 213
           VG +LS+F L++ +  F+  R +   R T+H ++ +   + S I +  +      G++  
Sbjct: 504 VGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIEN--EGGQVGL 561

Query: 214 RDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVP 273
           R  +   +LH    Y     + WM  EG+ L+ L+V     +    RW  L+G+G PL+ 
Sbjct: 562 RCRLVAGLLH----YCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLL- 616

Query: 274 TTIHAITRAVYFND-----NCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMR 328
             I  ++ A+Y         CWL  E   L+   GPV   ++ N    +  V  L  K  
Sbjct: 617 --IVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFS 674

Query: 329 ETH-EAESHMYLKAVKATMIL-VPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFF 386
           E + + +     +A+  T I  + LLG  +V   +   ++ L  +  YV   L   QG F
Sbjct: 675 EINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSL--VLTYVFTILNCLQGAF 732

Query: 387 VATIYCFCNNEVQTTVKRQWA 407
           +  ++C  N +V+    R+WA
Sbjct: 733 LYLLHCLLNKKVREEY-RKWA 752


>gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]
          Length = 742

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 68/261 (26%), Positives = 118/261 (45%), Gaps = 19/261 (7%)

Query: 154 VGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVR 213
           VG +LS+F L++ +  F+  R +   R T+H ++ +   + S I +  +      G++  
Sbjct: 460 VGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIEN--EGGQVGL 517

Query: 214 RDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVP 273
           R  +   +LH    Y     + WM  EG+ L+ L+V     +    RW  L+G+G PL+ 
Sbjct: 518 RCRLVAGLLH----YCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLL- 572

Query: 274 TTIHAITRAVYFND-----NCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMR 328
             I  ++ A+Y         CWL  E   L+   GPV   ++ N    +  V  L  K  
Sbjct: 573 --IVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFS 630

Query: 329 ETH-EAESHMYLKAVKATMIL-VPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFF 386
           E + + +     +A+  T I  + LLG  +V   +   ++ L  +  YV   L   QG F
Sbjct: 631 EINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSL--VLTYVFTILNCLQGAF 688

Query: 387 VATIYCFCNNEVQTTVKRQWA 407
           +  ++C  N +V+    R+WA
Sbjct: 689 LYLLHCLLNKKVREEY-RKWA 708


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.140    0.465 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,597,099
Number of Sequences: 37866
Number of extensions: 847820
Number of successful extensions: 2537
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 2353
Number of HSP's gapped (non-prelim): 79
length of query: 474
length of database: 18,247,518
effective HSP length: 106
effective length of query: 368
effective length of database: 14,233,722
effective search space: 5238009696
effective search space used: 5238009696
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.