Search of human proteins with 41406061

Search of human proteins with 41406061

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41406061 MOB1, Mps One Binder kinase activator-like 2C
isoform 2 [Homo sapiens]
         (216 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41406059 MOB1, Mps One Binder kinase activator-like 2C isofor...   451   e-127
gi|41406061 MOB1, Mps One Binder kinase activator-like 2C isofor...   451   e-127
gi|18677731 MOB-LAK [Homo sapiens]                                    354   3e-98
gi|41350330 MOB1, Mps One Binder kinase activator-like 2B [Homo ...   350   4e-97
gi|148747437 Mob4B protein [Homo sapiens]                             247   6e-66
gi|27735029 MOB1, Mps One Binder kinase activator-like 1A [Homo ...   241   3e-64
gi|34594669 HCCA2 protein [Homo sapiens]                              131   4e-31
gi|155030224 Mps One Binder kinase activator-like 3 isoform 3 [H...    47   9e-06
gi|41349451 Mps One Binder kinase activator-like 3 isoform 2 [Ho...    44   8e-05
gi|41349449 Mps One Binder kinase activator-like 3 isoform 1 [Ho...    44   8e-05
gi|54792138 helicase with zinc finger domain [Homo sapiens]            30   1.6  
gi|110347427 ubiquitin specific protease 34 [Homo sapiens]             28   7.8  

>gi|41406059 MOB1, Mps One Binder kinase activator-like 2C isoform 1
           [Homo sapiens]
          Length = 268

 Score =  451 bits (1161), Expect = e-127
 Identities = 216/216 (100%), Positives = 216/216 (100%)

Query: 1   MALCLKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWI 60
           MALCLKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWI
Sbjct: 53  MALCLKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWI 112

Query: 61  AVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMAL 120
           AVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMAL
Sbjct: 113 AVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMAL 172

Query: 121 LMDWIEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVFVHVYIHHFDSILSMGAEA 180
           LMDWIEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVFVHVYIHHFDSILSMGAEA
Sbjct: 173 LMDWIEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVFVHVYIHHFDSILSMGAEA 232

Query: 181 HVNTCYKHFYYFIREFSLVDQRELEPLREMTERICH 216
           HVNTCYKHFYYFIREFSLVDQRELEPLREMTERICH
Sbjct: 233 HVNTCYKHFYYFIREFSLVDQRELEPLREMTERICH 268


>gi|41406061 MOB1, Mps One Binder kinase activator-like 2C isoform 2
           [Homo sapiens]
          Length = 216

 Score =  451 bits (1161), Expect = e-127
 Identities = 216/216 (100%), Positives = 216/216 (100%)

Query: 1   MALCLKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWI 60
           MALCLKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWI
Sbjct: 1   MALCLKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWI 60

Query: 61  AVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMAL 120
           AVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMAL
Sbjct: 61  AVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMAL 120

Query: 121 LMDWIEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVFVHVYIHHFDSILSMGAEA 180
           LMDWIEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVFVHVYIHHFDSILSMGAEA
Sbjct: 121 LMDWIEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVFVHVYIHHFDSILSMGAEA 180

Query: 181 HVNTCYKHFYYFIREFSLVDQRELEPLREMTERICH 216
           HVNTCYKHFYYFIREFSLVDQRELEPLREMTERICH
Sbjct: 181 HVNTCYKHFYYFIREFSLVDQRELEPLREMTERICH 216


>gi|18677731 MOB-LAK [Homo sapiens]
          Length = 217

 Score =  354 bits (909), Expect = 3e-98
 Identities = 157/212 (74%), Positives = 188/212 (88%)

Query: 5   LKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWIAVHV 64
           LKQVF KDKTFRP+++FEPGTQRFEL+KKAQASL +GLDLR  V+LPPGE+++DW+AVHV
Sbjct: 6   LKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDWVAVHV 65

Query: 65  VDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMALLMDW 124
           VDFFNR+NLIYGT+++ C+E SCPVM+GGP+YEYRWQDE ++R+P  LSAPRYM LLMDW
Sbjct: 66  VDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMDLLMDW 125

Query: 125 IEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVFVHVYIHHFDSILSMGAEAHVNT 184
           IE  IN+E++FPT VG PFPKNF Q   KIL+RLFRVFVHVYIHHFD I  MG+EAHVNT
Sbjct: 126 IEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSEAHVNT 185

Query: 185 CYKHFYYFIREFSLVDQRELEPLREMTERICH 216
           CYKHFYYF++EF L+D +ELEPL+EMT R+CH
Sbjct: 186 CYKHFYYFVKEFGLIDTKELEPLKEMTARMCH 217


>gi|41350330 MOB1, Mps One Binder kinase activator-like 2B [Homo
           sapiens]
          Length = 216

 Score =  350 bits (899), Expect = 4e-97
 Identities = 155/216 (71%), Positives = 191/216 (88%)

Query: 1   MALCLKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWI 60
           M++ LKQVF KDKTFRP+++FEPGTQRFEL+K+AQASL SG+DL++ V+LP GE+ +DW+
Sbjct: 1   MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWV 60

Query: 61  AVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMAL 120
           AVHVVDFFNRINLIYGT+ E C+E +CPVM+GGP+YEYRWQD+ +Y++P  L AP+YM L
Sbjct: 61  AVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNL 120

Query: 121 LMDWIEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVFVHVYIHHFDSILSMGAEA 180
           LMDWIE  IN+EE+FPT VGVPFPKNF Q+C KIL RLFRVFVHVYIHHFD ++ MGAEA
Sbjct: 121 LMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEA 180

Query: 181 HVNTCYKHFYYFIREFSLVDQRELEPLREMTERICH 216
           HVNTCYKHFYYF+ E +L+D++ELEPL+EMT R+CH
Sbjct: 181 HVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH 216


>gi|148747437 Mob4B protein [Homo sapiens]
          Length = 216

 Score =  247 bits (630), Expect = 6e-66
 Identities = 106/202 (52%), Positives = 154/202 (76%), Gaps = 1/202 (0%)

Query: 13  KTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWIAVHVVDFFNRIN 72
           KTF+P+K    G+ ++EL K A+A+L SG +LR  V LP GE++++WIAV+ VDFFN+IN
Sbjct: 11  KTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRQAVMLPEGEDLNEWIAVNTVDFFNQIN 69

Query: 73  LIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMALLMDWIEGLINDE 132
           ++YGT+ E C+E SCPVM+ GPRYEY W D    ++P K SAP+Y+  LM W++  ++DE
Sbjct: 70  MLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDE 129

Query: 133 EVFPTRVGVPFPKNFQQVCTKILTRLFRVFVHVYIHHFDSILSMGAEAHVNTCYKHFYYF 192
            +FP+++GVPFPKNF  V   IL RLFRV+ H+Y  HFDS++ +  EAH+NT +KHF +F
Sbjct: 130 TLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFF 189

Query: 193 IREFSLVDQRELEPLREMTERI 214
           ++EF+L+D+REL PL+E+ E++
Sbjct: 190 VQEFNLIDRRELAPLQELIEKL 211


>gi|27735029 MOB1, Mps One Binder kinase activator-like 1A [Homo
           sapiens]
          Length = 216

 Score =  241 bits (616), Expect = 3e-64
 Identities = 102/202 (50%), Positives = 153/202 (75%), Gaps = 1/202 (0%)

Query: 13  KTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWIAVHVVDFFNRIN 72
           KTF+P+K    G+ ++EL K A+A+L SG +LR  V LP GE++++W+AV+ VDFFN+IN
Sbjct: 11  KTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLNEWVAVNTVDFFNQIN 69

Query: 73  LIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMALLMDWIEGLINDE 132
           ++YGT+ + C+E SCPVM+ GP+YEY W D    ++P K SAP+Y+  LM W++  ++DE
Sbjct: 70  MLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDE 129

Query: 133 EVFPTRVGVPFPKNFQQVCTKILTRLFRVFVHVYIHHFDSILSMGAEAHVNTCYKHFYYF 192
            +FP+++GVPFPKNF  V   IL RLFRV+ H+Y  HFD ++ +  EAH+NT +KHF +F
Sbjct: 130 TLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFF 189

Query: 193 IREFSLVDQRELEPLREMTERI 214
           ++EF+L+D+REL PL+E+ E++
Sbjct: 190 VQEFNLIDRRELAPLQELIEKL 211


>gi|34594669 HCCA2 protein [Homo sapiens]
          Length = 237

 Score =  131 bits (330), Expect = 4e-31
 Identities = 64/171 (37%), Positives = 102/171 (59%), Gaps = 3/171 (1%)

Query: 45  RSVVRLPPGENIDDWIAVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDER 104
           + +V LP   ++++W+A +   FF+ INL Y T++E C+  +C  MA     +Y W DER
Sbjct: 41  KELVVLPREIDLNEWLASNTTTFFHHINLQYSTISEFCTGETCQTMAVC-NTQYYWYDER 99

Query: 105 QYRRPAKLSAPRYMALLMDWIEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVFVH 164
              +  K +AP+Y+  +M  ++ L+ DE+VFPT+ G  FP +F+ +  KI   LF V  H
Sbjct: 100 G--KKVKCTAPQYVDFVMSSVQKLVTDEDVFPTKYGREFPSSFESLVRKICRHLFHVLAH 157

Query: 165 VYIHHFDSILSMGAEAHVNTCYKHFYYFIREFSLVDQRELEPLREMTERIC 215
           +Y  HF   L++    H+NT Y HF  F REF+L+D +E   + ++TE +C
Sbjct: 158 IYWAHFKETLALELHGHLNTLYVHFILFAREFNLLDPKETAIMDDLTEVLC 208


>gi|155030224 Mps One Binder kinase activator-like 3 isoform 3 [Homo
           sapiens]
          Length = 204

 Score = 47.4 bits (111), Expect = 9e-06
 Identities = 39/189 (20%), Positives = 80/189 (42%), Gaps = 17/189 (8%)

Query: 19  KRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWIAVHVVDFFNRINLIYGTM 78
           +R  PGT+   + +  +A   +   +  ++  P G++   W   H+  F   +N +   +
Sbjct: 11  RRNRPGTKAQYIQQNIRADCSN---IDKILEPPEGQDEGVWKYEHLRQFCLELNGLAVKL 67

Query: 79  AERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMALLMDWIEGLINDEEVFPTR 138
              C   +C  M    ++ +       ++ P +  A  Y    +D    L+N  + FP+R
Sbjct: 68  QSECHPDTCTQMTATEQWIFLCA---AHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSR 124

Query: 139 VGVPFPKNFQQVCTKILTRLFRVFVHVYIHH---FDSILSMGAEAHVNTCYKHFYYFIRE 195
           V +   ++       +  R++R+F H Y HH   FD       E     C++ F  F+ +
Sbjct: 125 VSIK--ESSVAKLGSVCRRIYRIFSHAYFHHRQIFDEY-----ENETFLCHR-FTKFVMK 176

Query: 196 FSLVDQREL 204
           ++L+ +  L
Sbjct: 177 YNLMSKDNL 185


>gi|41349451 Mps One Binder kinase activator-like 3 isoform 2 [Homo
           sapiens]
          Length = 193

 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 34/165 (20%), Positives = 70/165 (42%), Gaps = 14/165 (8%)

Query: 43  DLRSVVRLPPGENIDDWIAVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQD 102
           ++  ++  P G++   W   H+  F   +N +   +   C   +C  M    ++ +    
Sbjct: 21  NIDKILEPPEGQDEGVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCA- 79

Query: 103 ERQYRRPAKLSAPRYMALLMDWIEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVF 162
              ++ P +  A  Y    +D    L+N  + FP+RV +   ++       +  R++R+F
Sbjct: 80  --AHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIK--ESSVAKLGSVCRRIYRIF 135

Query: 163 VHVYIHH---FDSILSMGAEAHVNTCYKHFYYFIREFSLVDQREL 204
            H Y HH   FD       E     C++ F  F+ +++L+ +  L
Sbjct: 136 SHAYFHHRQIFDEY-----ENETFLCHR-FTKFVMKYNLMSKDNL 174


>gi|41349449 Mps One Binder kinase activator-like 3 isoform 1 [Homo
           sapiens]
          Length = 225

 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 34/165 (20%), Positives = 70/165 (42%), Gaps = 14/165 (8%)

Query: 43  DLRSVVRLPPGENIDDWIAVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQD 102
           ++  ++  P G++   W   H+  F   +N +   +   C   +C  M    ++ +    
Sbjct: 53  NIDKILEPPEGQDEGVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCA- 111

Query: 103 ERQYRRPAKLSAPRYMALLMDWIEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVF 162
              ++ P +  A  Y    +D    L+N  + FP+RV +   ++       +  R++R+F
Sbjct: 112 --AHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIK--ESSVAKLGSVCRRIYRIF 167

Query: 163 VHVYIHH---FDSILSMGAEAHVNTCYKHFYYFIREFSLVDQREL 204
            H Y HH   FD       E     C++ F  F+ +++L+ +  L
Sbjct: 168 SHAYFHHRQIFDEY-----ENETFLCHR-FTKFVMKYNLMSKDNL 206


>gi|54792138 helicase with zinc finger domain [Homo sapiens]
          Length = 1942

 Score = 30.0 bits (66), Expect = 1.6
 Identities = 17/37 (45%), Positives = 18/37 (48%)

Query: 174  LSMGAEAHVNTCYKHFYYFIREFSLVDQRELEPLREM 210
            L+  AE  V T Y  F   IRE S  DQ E   L EM
Sbjct: 1561 LTSSAEDEVETTYSRFQDLIRELSHRDQSETRELAEM 1597


>gi|110347427 ubiquitin specific protease 34 [Homo sapiens]
          Length = 3546

 Score = 27.7 bits (60), Expect = 7.8
 Identities = 12/50 (24%), Positives = 26/50 (52%), Gaps = 5/50 (10%)

Query: 123  DWIEGLINDEEVFPTRVGVPFPKN-----FQQVCTKILTRLFRVFVHVYI 167
            +W    + D++ +P ++ +  P       FQ++C  ++ RL  V  H+Y+
Sbjct: 2344 EWFLDRMADDDWWPMQILIKCPNQIVRQMFQRLCIHVIQRLRPVHAHLYL 2393


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.141    0.448 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,570,536
Number of Sequences: 37866
Number of extensions: 360379
Number of successful extensions: 813
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 799
Number of HSP's gapped (non-prelim): 12
length of query: 216
length of database: 18,247,518
effective HSP length: 98
effective length of query: 118
effective length of database: 14,536,650
effective search space: 1715324700
effective search space used: 1715324700
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.