Guide to the Human Genome
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Search of human proteins with 41393561

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41393561 leucine aminopeptidase 3 [Homo sapiens]
         (519 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41393561 leucine aminopeptidase 3 [Homo sapiens]                  1034   0.0  
gi|47155554 aminopeptidase-like 1 [Homo sapiens]                      138   1e-32
gi|122937195 plasma membrane associated protein, S3-12 [Homo sap...    34   0.28 
gi|31543093 galactosidase, beta 1-like 2 [Homo sapiens]                30   5.3  
gi|83921609 hypothetical protein LOC127254 [Homo sapiens]              29   9.1  

>gi|41393561 leucine aminopeptidase 3 [Homo sapiens]
          Length = 519

 Score = 1034 bits (2674), Expect = 0.0
 Identities = 519/519 (100%), Positives = 519/519 (100%)

Query: 1   MFLLPLPAAGRVVVRRLAVRRFGSRSLSTADMTKGLVLGIYSKEKEDDVPQFTSAGENFD 60
           MFLLPLPAAGRVVVRRLAVRRFGSRSLSTADMTKGLVLGIYSKEKEDDVPQFTSAGENFD
Sbjct: 1   MFLLPLPAAGRVVVRRLAVRRFGSRSLSTADMTKGLVLGIYSKEKEDDVPQFTSAGENFD 60

Query: 61  KLLAGKLRETLNISGPPLKAGKTRTFYGLHQDFPSVVLVGLGKKAAGIDEQENWHEGKEN 120
           KLLAGKLRETLNISGPPLKAGKTRTFYGLHQDFPSVVLVGLGKKAAGIDEQENWHEGKEN
Sbjct: 61  KLLAGKLRETLNISGPPLKAGKTRTFYGLHQDFPSVVLVGLGKKAAGIDEQENWHEGKEN 120

Query: 121 IRAAVAAGCRQIQDLELSSVEVDPCGDAQAAAEGAVLGLYEYDDLKQKKKMAVSAKLYGS 180
           IRAAVAAGCRQIQDLELSSVEVDPCGDAQAAAEGAVLGLYEYDDLKQKKKMAVSAKLYGS
Sbjct: 121 IRAAVAAGCRQIQDLELSSVEVDPCGDAQAAAEGAVLGLYEYDDLKQKKKMAVSAKLYGS 180

Query: 181 GDQEAWQKGVLFASGQNLARQLMETPANEMTPTRFAEIIEKNLKSASSKTEVHIRPKSWI 240
           GDQEAWQKGVLFASGQNLARQLMETPANEMTPTRFAEIIEKNLKSASSKTEVHIRPKSWI
Sbjct: 181 GDQEAWQKGVLFASGQNLARQLMETPANEMTPTRFAEIIEKNLKSASSKTEVHIRPKSWI 240

Query: 241 EEQAMGSFLSVAKGSDEPPVFLEIHYKGSPNANEPPLVFVGKGITFDSGGISIKASANMD 300
           EEQAMGSFLSVAKGSDEPPVFLEIHYKGSPNANEPPLVFVGKGITFDSGGISIKASANMD
Sbjct: 241 EEQAMGSFLSVAKGSDEPPVFLEIHYKGSPNANEPPLVFVGKGITFDSGGISIKASANMD 300

Query: 301 LMRADMGGAATICSAIVSAAKLNLPINIIGLAPLCENMPSGKANKPGDVVRAKNGKTIQV 360
           LMRADMGGAATICSAIVSAAKLNLPINIIGLAPLCENMPSGKANKPGDVVRAKNGKTIQV
Sbjct: 301 LMRADMGGAATICSAIVSAAKLNLPINIIGLAPLCENMPSGKANKPGDVVRAKNGKTIQV 360

Query: 361 DNTDAEGRLILADALCYAHTFNPKVILNAATLTGAMDVALGSGATGVFTNSSWLWNKLFE 420
           DNTDAEGRLILADALCYAHTFNPKVILNAATLTGAMDVALGSGATGVFTNSSWLWNKLFE
Sbjct: 361 DNTDAEGRLILADALCYAHTFNPKVILNAATLTGAMDVALGSGATGVFTNSSWLWNKLFE 420

Query: 421 ASIETGDRVWRMPLFEHYTRQVVDCQLADVNNIGKYRSAGACTAAAFLKEFVTHPKWAHL 480
           ASIETGDRVWRMPLFEHYTRQVVDCQLADVNNIGKYRSAGACTAAAFLKEFVTHPKWAHL
Sbjct: 421 ASIETGDRVWRMPLFEHYTRQVVDCQLADVNNIGKYRSAGACTAAAFLKEFVTHPKWAHL 480

Query: 481 DIAGVMTNKDEVPYLRKGMTGRPTRTLIEFLLRFSQDNA 519
           DIAGVMTNKDEVPYLRKGMTGRPTRTLIEFLLRFSQDNA
Sbjct: 481 DIAGVMTNKDEVPYLRKGMTGRPTRTLIEFLLRFSQDNA 519


>gi|47155554 aminopeptidase-like 1 [Homo sapiens]
          Length = 523

 Score =  138 bits (347), Expect = 1e-32
 Identities = 96/298 (32%), Positives = 145/298 (48%), Gaps = 17/298 (5%)

Query: 195 GQNLARQLMETPANEMTPTRFAEIIEKNLKSASSKTEVHIRPKSWIEEQAMGSFLSVAKG 254
           G  LA ++++TP NEM    F E I K  K       + IR +  ++ +  G    V K 
Sbjct: 177 GVRLAARIVDTPCNEMNTDTFLEEINKVGKELGIIPTI-IRDEE-LKTRGFGGIYGVGKA 234

Query: 255 SDEPPVFLEIHYKGSPNANEPPLVFVGKGITFDSGGISIKASANMDLMRADMGGAATICS 314
           +  PP    + +  +P+     + +VGKGI +D+GG+SIK    M  M+ D GGAA +  
Sbjct: 235 ALHPPALAVLSH--TPDGATQTIAWVGKGIVYDTGGLSIKGKTTMPGMKRDCGGAAAVLG 292

Query: 315 AIVSAAKLNLPINIIGLAPLCENMPSGKANKPGDVVRAKNGKTIQVDNTDAEGRLILADA 374
           A  +A K     N+  +  L EN     A +P D+    +GKT++++NTDAEGRL+LAD 
Sbjct: 293 AFRAAIKQGFKDNLHAVFCLAENSVGPNATRPDDIHLLYSGKTVEINNTDAEGRLVLADG 352

Query: 375 LCYA-HTFNPKVILNAATLTGAMDVALGSGATGVFTNSSWLWNKLFEASIETGDRVWRMP 433
           + YA       +IL+ ATLTGA  +A G     V TNS+       +A  + GD V  + 
Sbjct: 353 VSYACKDLGADIILDMATLTGAQGIATGKYHAAVLTNSAEWEAACVKAGRKCGDLVHPLV 412

Query: 434 L-----FEHYTRQVVDCQLADVNNIGKYRSAGACTAAAFLKEFVTHP---KWAHLDIA 483
                 F  +T  V D +    N++    ++ +  A  F+   +       W HLDIA
Sbjct: 413 YCPELHFSEFTSAVADMK----NSVADRDNSPSSCAGLFIASHIGFDWPGVWVHLDIA 466


>gi|122937195 plasma membrane associated protein, S3-12 [Homo
           sapiens]
          Length = 1357

 Score = 34.3 bits (77), Expect = 0.28
 Identities = 52/247 (21%), Positives = 87/247 (35%), Gaps = 34/247 (13%)

Query: 192 FASGQNLARQLMET----PANEMTPTRFAEIIEKNLKSASSKTEVHIRPKSWIEEQAMGS 247
           F+S +NL      +    PA + T    AE  +   + A+   +       W E++   S
Sbjct: 14  FSSARNLVANAHSSARARPAADPTGAPAAEAAQPQAQVAAHPEQT----APWTEKELQPS 69

Query: 248 FLSVAKGSDEPPVFLEIHYKGSPNANEPPLVFVGKGITFDSGGISIKASA---------- 297
              +  G+ +         K + ++    +V V KG+    GG+    SA          
Sbjct: 70  EKQMVSGAKDLVCSKMSRAKDAVSSGVASVVDVAKGVV--QGGLDTTRSALTGTKEVVSS 127

Query: 298 ----NMDLMRADMGGAATICSAIVSAAKLNLPINIIGLAPLCENMPSGKANKPGDVVRAK 353
                MD+ +  + G      A+++  K  +   + G      N+  G      D  +  
Sbjct: 128 GVTGAMDMAKGAVQGGLDTSKAVLTGTKDTVSTGLTGAV----NVAKGTVQAGVDTTKTV 183

Query: 354 NGKTIQVDNTDAEGRLILADALCYAHTFNPKVILNAAT------LTGAMDVALGSGATGV 407
              T     T   G + LA           K +L          LTGA++VA GS  TGV
Sbjct: 184 LTGTKDTVTTGVMGAVNLAKGTVQTGVETSKAVLTGTKDAVSTGLTGAVNVARGSIQTGV 243

Query: 408 FTNSSWL 414
            T+ + L
Sbjct: 244 DTSKTVL 250


>gi|31543093 galactosidase, beta 1-like 2 [Homo sapiens]
          Length = 636

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 11/17 (64%), Positives = 14/17 (82%)

Query: 184 EAWQKGVLFASGQNLAR 200
           E W+KGV+F +GQNL R
Sbjct: 569 EGWEKGVVFINGQNLGR 585


>gi|83921609 hypothetical protein LOC127254 [Homo sapiens]
          Length = 1530

 Score = 29.3 bits (64), Expect = 9.1
 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 10/102 (9%)

Query: 108  IDEQENWHEGKENIRAAVAAGCRQIQDLELSSVEVDPCGDAQAAAEGAVLGLYEYDDLKQ 167
            + E+E WH+  E +    AAG   +++L  S  EV P  +          G+     L++
Sbjct: 1381 VAEEETWHQQDELVGKTAAAGKVVVEELARSGEEV-PAAEEMTVTYTTEAGVGTPGALER 1439

Query: 168  KKKMAVSAKLYGSGDQEAWQKGVLFASGQNLARQLMETPANE 209
            K       +  GS  QEA       A+G    RQ  ET A E
Sbjct: 1440 KTSGLGQEQEEGSEGQEA-------ATGSGDGRQ--ETGAAE 1472


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,435,252
Number of Sequences: 37866
Number of extensions: 856721
Number of successful extensions: 1644
Number of sequences better than 10.0: 5
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1625
Number of HSP's gapped (non-prelim): 18
length of query: 519
length of database: 18,247,518
effective HSP length: 107
effective length of query: 412
effective length of database: 14,195,856
effective search space: 5848692672
effective search space used: 5848692672
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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