Search of human proteins with 40548387

Search of human proteins with 40548387

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40548387 O-acyltransferase (membrane bound) domain
containing 2 [Homo sapiens]
         (520 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40548387 O-acyltransferase (membrane bound) domain containing...  1058   0.0  
gi|122937404 membrane bound O-acyltransferase domain containing ...   565   e-161
gi|42542394 lysophosphatidylcholine acyltransferase 3 [Homo sapi...   137   3e-32
gi|189571629 membrane bound O-acyltransferase domain containing ...   119   5e-27
gi|225703079 membrane bound O-acyltransferase domain containing ...   117   3e-26
gi|225703081 membrane bound O-acyltransferase domain containing ...   110   2e-24
gi|225703033 membrane bound O-acyltransferase domain containing ...   110   2e-24
gi|225703037 membrane bound O-acyltransferase domain containing ...    56   7e-08
gi|45439333 porcupine isoform C [Homo sapiens]                         52   1e-06
gi|45439331 porcupine isoform B [Homo sapiens]                         50   4e-06
gi|45439329 porcupine isoform A [Homo sapiens]                         50   4e-06
gi|45439335 porcupine isoform D [Homo sapiens]                         50   5e-06
gi|45439337 porcupine isoform E [Homo sapiens]                         46   7e-05
gi|125660451 MAS-related GPR, member X1 [Homo sapiens]                 32   1.1  
gi|154275767 ADAMTS-like 1 isoform 4 precursor [Homo sapiens]          30   5.3  
gi|4557859 somatostatin receptor 2 [Homo sapiens]                      29   9.1  
gi|170932464 Yip1 interacting factor homolog [Homo sapiens]            29   9.1  

>gi|40548387 O-acyltransferase (membrane bound) domain containing 2
           [Homo sapiens]
          Length = 520

 Score = 1058 bits (2736), Expect = 0.0
 Identities = 520/520 (100%), Positives = 520/520 (100%)

Query: 1   MATTSTTGSTLLQPLSNAVQLPIDQVNFVVCQLFALLAAIWFRTYLHSSKTSSFIRHVVA 60
           MATTSTTGSTLLQPLSNAVQLPIDQVNFVVCQLFALLAAIWFRTYLHSSKTSSFIRHVVA
Sbjct: 1   MATTSTTGSTLLQPLSNAVQLPIDQVNFVVCQLFALLAAIWFRTYLHSSKTSSFIRHVVA 60

Query: 61  TLLGLYLALFCFGWYALHFLVQSGISYCIMIIIGVENMHNYCFVFALGYLTVCQVTRVYI 120
           TLLGLYLALFCFGWYALHFLVQSGISYCIMIIIGVENMHNYCFVFALGYLTVCQVTRVYI
Sbjct: 61  TLLGLYLALFCFGWYALHFLVQSGISYCIMIIIGVENMHNYCFVFALGYLTVCQVTRVYI 120

Query: 121 FDYGQYSADFSGPMMIITQKITSLACEIHDGMFRKDEELTSSQRDLAVRRMPSLLEYLSY 180
           FDYGQYSADFSGPMMIITQKITSLACEIHDGMFRKDEELTSSQRDLAVRRMPSLLEYLSY
Sbjct: 121 FDYGQYSADFSGPMMIITQKITSLACEIHDGMFRKDEELTSSQRDLAVRRMPSLLEYLSY 180

Query: 181 NCNFMGILAGPLCSYKDYITFIEGRSYHITQSGENGKEETQYERTEPSPNTAVVQKLLVC 240
           NCNFMGILAGPLCSYKDYITFIEGRSYHITQSGENGKEETQYERTEPSPNTAVVQKLLVC
Sbjct: 181 NCNFMGILAGPLCSYKDYITFIEGRSYHITQSGENGKEETQYERTEPSPNTAVVQKLLVC 240

Query: 241 GLSLLFHLTICTTLPVEYNIDEHFQATASWPTKIIYLYISLLAARPKYYFAWTLADAINN 300
           GLSLLFHLTICTTLPVEYNIDEHFQATASWPTKIIYLYISLLAARPKYYFAWTLADAINN
Sbjct: 241 GLSLLFHLTICTTLPVEYNIDEHFQATASWPTKIIYLYISLLAARPKYYFAWTLADAINN 300

Query: 301 AAGFGFRGYDENGAARWDLISNLRIQQIEMSTSFKMFLDNWNIQTALWLKRVCYERTSFS 360
           AAGFGFRGYDENGAARWDLISNLRIQQIEMSTSFKMFLDNWNIQTALWLKRVCYERTSFS
Sbjct: 301 AAGFGFRGYDENGAARWDLISNLRIQQIEMSTSFKMFLDNWNIQTALWLKRVCYERTSFS 360

Query: 361 PTIQTFILSAIWHGVYPGYYLTFLTGVLMTLAARAMRNNFRHYFIEPSQLKLFYDVITWI 420
           PTIQTFILSAIWHGVYPGYYLTFLTGVLMTLAARAMRNNFRHYFIEPSQLKLFYDVITWI
Sbjct: 361 PTIQTFILSAIWHGVYPGYYLTFLTGVLMTLAARAMRNNFRHYFIEPSQLKLFYDVITWI 420

Query: 421 VTQVAISYTVVPFVLLSIKPSLTFYSSWYYCLHILGILVLLLLPVKKTQRRKNTHENIQL 480
           VTQVAISYTVVPFVLLSIKPSLTFYSSWYYCLHILGILVLLLLPVKKTQRRKNTHENIQL
Sbjct: 421 VTQVAISYTVVPFVLLSIKPSLTFYSSWYYCLHILGILVLLLLPVKKTQRRKNTHENIQL 480

Query: 481 SQSKKFDEGENSLGQNSFSTTNNVCNQNQEIASRHSSLKQ 520
           SQSKKFDEGENSLGQNSFSTTNNVCNQNQEIASRHSSLKQ
Sbjct: 481 SQSKKFDEGENSLGQNSFSTTNNVCNQNQEIASRHSSLKQ 520


>gi|122937404 membrane bound O-acyltransferase domain containing 1
           [Homo sapiens]
          Length = 495

 Score =  565 bits (1456), Expect = e-161
 Identities = 265/476 (55%), Positives = 348/476 (73%), Gaps = 3/476 (0%)

Query: 6   TTGSTLLQPLSNAVQLPIDQVNFVVCQLFALLAAIWFRTYLHSSKTSSFIRHVVATLLGL 65
           TTGST L PLS  + +P+DQVNFVVCQL AL AA WFR YL    TSS +RH VAT+ G+
Sbjct: 14  TTGSTYLHPLSELLGIPLDQVNFVVCQLVALFAAFWFRIYLRPGTTSSDVRHAVATIFGI 73

Query: 66  YLALFCFGWYALHFLVQSGISYCIMIIIGVENMHNYCFVFALGYLTVCQVTRVYIFDYGQ 125
           Y  +FCFGWY++H  V   + Y IM+   V N+H Y F  A+GYLT+C ++R+YIF YG 
Sbjct: 74  YFVIFCFGWYSVHLFVLVLMCYAIMVTASVSNIHRYSFFVAMGYLTICHISRIYIFHYGI 133

Query: 126 YSADFSGPMMIITQKITSLACEIHDGMFRKDEELTSSQRDLAVRRMPSLLEYLSYNCNFM 185
            + DFSGP+MI+TQKIT+LA ++HDG+ R+ E+L++ Q  LA++  PS LEYLSY  NFM
Sbjct: 134 LTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSAEQHRLAIKVKPSFLEYLSYLLNFM 193

Query: 186 GILAGPLCSYKDYITFIEGRSYHITQSGENGKEETQYERTEPSPNTAVVQKLLVCGLSLL 245
            ++AGP  ++KDYI FIEG+  H+     N K +  +   EPSP  AV+ KL +  +SLL
Sbjct: 194 SVIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFHSLPEPSPTGAVIHKLGITLVSLL 253

Query: 246 FHLTICTTLPVEYNIDEHFQATASWPTKIIYLYISLLAARPKYYFAWTLADAINNAAGFG 305
             LT+  T PV   +D+ F   AS+P ++ YLY+ + A++PKYYFAWTLADA+NNAAGFG
Sbjct: 254 LFLTLTKTFPVTCLVDDWFVHKASFPARLCYLYVVMQASKPKYYFAWTLADAVNNAAGFG 313

Query: 306 FRGYDENGAARWDLISNLRIQQIEMSTSFKMFLDNWNIQTALWLKRVCYERTSFSPTIQT 365
           F G D+NG   WDL+SNL I +IE +TSFKM+L+NWNIQTA WLK VCY+R  + PT+ T
Sbjct: 314 FSGVDKNGNFCWDLLSNLNIWKIETATSFKMYLENWNIQTATWLKCVCYQRVPWYPTVLT 373

Query: 366 FILSAIWHGVYPGYYLTFLTGVLMTLAARAMRNNFRHYFIEPSQLKLFYDVITWIVTQVA 425
           FILSA+WHGVYPGYY TFLTG+L+TLAARA+RNN+RHYF+    LK  YD  TW VTQ+A
Sbjct: 374 FILSALWHGVYPGYYFTFLTGILVTLAARAVRNNYRHYFLSSRALKAVYDAGTWAVTQLA 433

Query: 426 ISYTVVPFVLLSIKPSLTFYSSWYYCLHILGILVLLLLPVK---KTQRRKNTHENI 478
           +SYTV PFV+L+++P+++ Y S Y+ LHI+ +L++L LP+K    TQRR  T  +I
Sbjct: 434 VSYTVAPFVMLAVEPTISLYKSMYFYLHIISLLIILFLPMKPQAHTQRRPQTLNSI 489


>gi|42542394 lysophosphatidylcholine acyltransferase 3 [Homo
           sapiens]
          Length = 487

 Score =  137 bits (344), Expect = 3e-32
 Identities = 112/444 (25%), Positives = 197/444 (44%), Gaps = 46/444 (10%)

Query: 39  AIWFRTYLHSSKTSSFIRHVVATLLGLYLALFCFGWYALHFLVQSGISYCIMIIIG---V 95
           A+++R YL   +T  ++ H+  T  GL +A F FG    H L+   + + I+ ++G    
Sbjct: 55  ALFYRHYLFYKET--YLIHLFHTFTGLSIAYFNFGNQLYHSLLCIVLQFLILRLMGRTIT 112

Query: 96  ENMHNYCFVFALGYLTVCQVTRVYIFDYGQYSADFSGPMMIITQKITSLACEIHDGMFRK 155
             +  +CF  A  YL    +   Y    G Y   ++ P  ++T K+  LA +  DG  + 
Sbjct: 113 AVLTTFCFQMA--YL----LAGYYYTATGNYDIKWTMPHCVLTLKLIGLAVDYFDGG-KD 165

Query: 156 DEELTSSQRDLAVRRMPSLLEYLSYNCNFMGILAGPLCSYKDYITFIEGRSYHITQSGEN 215
              L+S Q+  A+R +PSLLE   ++  +   L GP  S   Y+  ++G    I      
Sbjct: 166 QNSLSSEQQKYAIRGVPSLLEVAGFSYFYGAFLVGPQFSMNHYMKLVQGELIDIP----- 220

Query: 216 GKEETQYERTEPSPNTAV-VQKLLVCGLSLLFHLTICTT-LPVEYNIDEHFQATASWPTK 273
           GK           PN+ +   K L  GL  L   T+ +  +  +Y + E +     W  +
Sbjct: 221 GK----------IPNSIIPALKRLSLGLFYLVGYTLLSPHITEDYLLTEDYDNHPFW-FR 269

Query: 274 IIYLYISLLAARPKYYFAWTLADAINNAAGFGFRGYDENGAARWDLISNLRIQQIEMSTS 333
            +Y+ I       KY   W + + +    G GF G++E G A+WD  +N+++   E +  
Sbjct: 270 CMYMLIWGKFVLYKYVTCWLVTEGVCILTGLGFNGFEEKGKAKWDACANMKVWLFETNPR 329

Query: 334 FKMFLDNWNIQTALWLKRVCYERTSFSPTIQ-----TFILSAIWHGVYPGYYLTFLTGVL 388
           F   + ++NI T  W+ R  ++R  F    +     + +  A+WHG++ GY + F    L
Sbjct: 330 FTGTIASFNINTNAWVARYIFKRLKFLGNKELSQGLSLLFLALWHGLHSGYLVCFQMEFL 389

Query: 389 MTLAARAMRNNFRHYFIEPSQLKL--------FYDVITWIVTQVAISYTVVPFVLLSIKP 440
           + +  R      +     P+  KL        FY ++   +  + + Y++  F L +   
Sbjct: 390 IVIVERQAARLIQE---SPTLSKLAAITVLQPFYYLVQQTIHWLFMGYSMTAFCLFTWDK 446

Query: 441 SLTFYSSWYYCLHILGILVLLLLP 464
            L  Y S Y+  HI  + +L +LP
Sbjct: 447 WLKVYKSIYFLGHIFFLSLLFILP 470


>gi|189571629 membrane bound O-acyltransferase domain containing 4
           [Homo sapiens]
          Length = 435

 Score =  119 bits (299), Expect = 5e-27
 Identities = 101/424 (23%), Positives = 189/424 (44%), Gaps = 36/424 (8%)

Query: 52  SSFIRHVVATLLGLYLALFCFGWYALHFLVQSGISYCIMIIIGVENMHNYCFVFALGYLT 111
           S+  R++     G  LA+   G YA+     +  +  ++  +  + +H + F F + + T
Sbjct: 36  STRARYLFLLTGGGALAVAAMGSYAVLVFTPAVCAVALLCSLAPQQVHRWTFCFQMSWQT 95

Query: 112 VCQV----TRVYIFDYGQYSADFS-GPMMIITQKITSLACEIHDGMFRKDEELTSSQRDL 166
           +C +    T  Y+ +        +   +M++TQ++TSL+ +I +G  +       S+  L
Sbjct: 96  LCHLGLHYTEYYLHEPPSVRFCITLSSLMLLTQRVTSLSLDICEGKVKAASGGFRSRSSL 155

Query: 167 AVRRMPSLLEYLSYNCNFMGILAGPLCSYKDYITFIEGRSYHITQSGENGKEETQYERTE 226
           +   +   L Y SY   F  +L G LCS++ +   ++G S                    
Sbjct: 156 S-EHVCKALPYFSYLLFFPALLGGSLCSFQRFQARVQGSS-----------------ALH 197

Query: 227 PSPNTAVV--QKLLVCGLSLLFHLTICTTLPVEYNIDEHFQATASWPTKIIYLYISLLAA 284
           P  +   +  + L + GL        C  + V   +D     T     + IY+  +    
Sbjct: 198 PRHSFWALSWRGLQILGLE-------CLNVAVSRVVDAGAGLTDCQQFECIYVVWTTAGL 250

Query: 285 -RPKYYFAWTLADAINNAAGFGFRGYDENGAARWDLISNLRIQQIEMSTSFKMFLDNWNI 343
            +  YY  W L D++ +AAGFG       G   +  + +  I  +E +    +F   WN 
Sbjct: 251 FKLTYYSHWILDDSLLHAAGFGPELGQSPGEEGY--VPDADIWTLERTHRISVFSRKWNQ 308

Query: 344 QTALWLKRVCYERTSFSPTIQTFILSAIWHGVYPGYYLTFLTGVLMTLAARAMRNNFRHY 403
            TA WL+R+ ++ +   P +QTF  SA WHG++PG    F+   +M + A  + ++F + 
Sbjct: 309 STARWLRRLVFQHSRAWPLLQTFAFSAWWHGLHPGQVFGFVCWAVM-VEADYLIHSFANE 367

Query: 404 FIEPSQLKLFYDVITWIVTQVAISYTVVPFVLLSIKPSLTFYSSWYYCLHILGILVLLLL 463
           FI    ++LFY  +TW  TQ+ I+Y ++   + S+       +S+     ++  ++LLLL
Sbjct: 368 FIRSWPMRLFYRTLTWAHTQLIIAYIMLAVEVRSLSSLWLLCNSYNSVFPMVYCILLLLL 427

Query: 464 PVKK 467
             +K
Sbjct: 428 AKRK 431


>gi|225703079 membrane bound O-acyltransferase domain containing 7
           isoform 1 [Homo sapiens]
          Length = 472

 Score =  117 bits (293), Expect = 3e-26
 Identities = 118/464 (25%), Positives = 192/464 (41%), Gaps = 60/464 (12%)

Query: 60  ATLLGLYLALFCFGWYALHFLVQSGISYCIMIIIGVENMHNYCFVFALGYLTVCQVTRVY 119
           A  +GL L LF  G + LH LV   +    +I     + H     +   YL   +   + 
Sbjct: 34  AAAVGLGLTLFTCGPHTLHSLVTI-LGTWALIQAQPCSCHALALAWTFSYLLFFRA--LS 90

Query: 120 IFDYGQYSADFSGPMMIITQKITSLACEIHDGMFRKDEELTSSQRDLAVRRM----PSLL 175
           +      +   +   +++T K+ SLA E+ D    + +E+ S         +    PSL+
Sbjct: 91  LLGLPTPTPFTNAVQLLLTLKLVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLM 150

Query: 176 EYLSYNCNFMGILAGPLCSYKDYITFIEGRSYHITQSGENGKEETQYERTEPSPNTAVVQ 235
           E LSY+  ++GI+ GP   Y+ Y+ ++E         G          R  P+P      
Sbjct: 151 ETLSYSYCYVGIMTGPFFRYRTYLDWLEQPF-----PGAVPSLRPLLRRAWPAPL----- 200

Query: 236 KLLVCGLSLLFHLTICTTLPVEYNIDEHFQATASWPTKIIYLYISLLAARPKYYFAWTLA 295
                   LLF L+     P+E   ++ F A    P ++ Y+     A R ++Y AW  A
Sbjct: 201 ------FGLLFLLS-SHLFPLEAVREDAFYARPL-PARLFYMIPVFFAFRMRFYVAWIAA 252

Query: 296 DAINNAAGFGFRGYDENGAAR------------------------WDLISNLRIQQIEMS 331
           +    AAGFG   Y     AR                        ++ I N+     +  
Sbjct: 253 ECGCIAAGFG--AYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFC 310

Query: 332 TSFKMFLDNWNIQTALWLKRVCYE----RTSFSPTIQTFILSAIWHGVYPGYYLTFLTGV 387
              +  +  WN+    WL +  Y+    R+    +  T +LSA WHG++PGYYL+FLT +
Sbjct: 311 VRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLT-I 369

Query: 388 LMTLAARAMRNNFRHYFIEPSQLKLFYDVITWIVTQVAISYTVVPFVLLSIKPSLTFYSS 447
            + LAA     +     + P   K  +D + W +   A  Y  + FVLLS+  +L +++S
Sbjct: 370 PLCLAAEGRLESALRGRLSPGGQKA-WDWVHWFLKMRAYDYMCMGFVLLSLADTLRYWAS 428

Query: 448 WYYCLHILGILVL---LLLPVKKTQRRKNTHENIQLSQSKKFDE 488
            Y+C+H L +  L   L L      RRK   +   L+  K  +E
Sbjct: 429 IYFCIHFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLREE 472


>gi|225703081 membrane bound O-acyltransferase domain containing 7
           isoform 2 [Homo sapiens]
          Length = 399

 Score =  110 bits (276), Expect = 2e-24
 Identities = 104/393 (26%), Positives = 166/393 (42%), Gaps = 62/393 (15%)

Query: 131 SGPMMIITQKITSLACEIHDGMFRKDEELTSSQRDLAVRRM----PSLLEYLSYNCNFMG 186
           SGP +++     SLA E+ D    + +E+ S         +    PSL+E LSY+  ++G
Sbjct: 34  SGPALLV-----SLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVG 88

Query: 187 ILAGPLCSYKDYITFIEGRSYHITQSGENGKEETQYERTEPSPNTAVVQKLLVCGLSLLF 246
           I+ GP   Y+ Y+ ++E         G          R  P+P              LLF
Sbjct: 89  IMTGPFFRYRTYLDWLEQPF-----PGAVPSLRPLLRRAWPAPL-----------FGLLF 132

Query: 247 HLTICTTLPVEYNIDEHFQATASWPTKIIYLYISLLAARPKYYFAWTLADAINNAAGFGF 306
            L+     P+E   ++ F A    P ++ Y+     A R ++Y AW  A+    AAGFG 
Sbjct: 133 LLS-SHLFPLEAVREDAFYARPL-PARLFYMIPVFFAFRMRFYVAWIAAECGCIAAGFG- 189

Query: 307 RGYDENGAAR------------------------WDLISNLRIQQIEMSTSFKMFLDNWN 342
             Y     AR                        ++ I N+     +     +  +  WN
Sbjct: 190 -AYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRVRDGMRYWN 248

Query: 343 IQTALWLKRVCYE----RTSFSPTIQTFILSAIWHGVYPGYYLTFLTGVLMTLAARAMRN 398
           +    WL +  Y+    R+    +  T +LSA WHG++PGYYL+FLT + + LAA     
Sbjct: 249 MTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLT-IPLCLAAEGRLE 307

Query: 399 NFRHYFIEPSQLKLFYDVITWIVTQVAISYTVVPFVLLSIKPSLTFYSSWYYCLHILGIL 458
           +     + P   K  +D + W +   A  Y  + FVLLS+  +L +++S Y+C+H L + 
Sbjct: 308 SALRGRLSPGGQKA-WDWVHWFLKMRAYDYMCMGFVLLSLADTLRYWASIYFCIHFLALA 366

Query: 459 VL---LLLPVKKTQRRKNTHENIQLSQSKKFDE 488
            L   L L      RRK   +   L+  K  +E
Sbjct: 367 ALGLGLALGGGSPSRRKAASQPTSLAPEKLREE 399


>gi|225703033 membrane bound O-acyltransferase domain containing 7
           isoform 2 [Homo sapiens]
          Length = 399

 Score =  110 bits (276), Expect = 2e-24
 Identities = 104/393 (26%), Positives = 166/393 (42%), Gaps = 62/393 (15%)

Query: 131 SGPMMIITQKITSLACEIHDGMFRKDEELTSSQRDLAVRRM----PSLLEYLSYNCNFMG 186
           SGP +++     SLA E+ D    + +E+ S         +    PSL+E LSY+  ++G
Sbjct: 34  SGPALLV-----SLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVG 88

Query: 187 ILAGPLCSYKDYITFIEGRSYHITQSGENGKEETQYERTEPSPNTAVVQKLLVCGLSLLF 246
           I+ GP   Y+ Y+ ++E         G          R  P+P              LLF
Sbjct: 89  IMTGPFFRYRTYLDWLEQPF-----PGAVPSLRPLLRRAWPAPL-----------FGLLF 132

Query: 247 HLTICTTLPVEYNIDEHFQATASWPTKIIYLYISLLAARPKYYFAWTLADAINNAAGFGF 306
            L+     P+E   ++ F A    P ++ Y+     A R ++Y AW  A+    AAGFG 
Sbjct: 133 LLS-SHLFPLEAVREDAFYARPL-PARLFYMIPVFFAFRMRFYVAWIAAECGCIAAGFG- 189

Query: 307 RGYDENGAAR------------------------WDLISNLRIQQIEMSTSFKMFLDNWN 342
             Y     AR                        ++ I N+     +     +  +  WN
Sbjct: 190 -AYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRVRDGMRYWN 248

Query: 343 IQTALWLKRVCYE----RTSFSPTIQTFILSAIWHGVYPGYYLTFLTGVLMTLAARAMRN 398
           +    WL +  Y+    R+    +  T +LSA WHG++PGYYL+FLT + + LAA     
Sbjct: 249 MTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLT-IPLCLAAEGRLE 307

Query: 399 NFRHYFIEPSQLKLFYDVITWIVTQVAISYTVVPFVLLSIKPSLTFYSSWYYCLHILGIL 458
           +     + P   K  +D + W +   A  Y  + FVLLS+  +L +++S Y+C+H L + 
Sbjct: 308 SALRGRLSPGGQKA-WDWVHWFLKMRAYDYMCMGFVLLSLADTLRYWASIYFCIHFLALA 366

Query: 459 VL---LLLPVKKTQRRKNTHENIQLSQSKKFDE 488
            L   L L      RRK   +   L+  K  +E
Sbjct: 367 ALGLGLALGGGSPSRRKAASQPTSLAPEKLREE 399


>gi|225703037 membrane bound O-acyltransferase domain containing 7
           isoform 3 [Homo sapiens]
          Length = 344

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 62/250 (24%), Positives = 101/250 (40%), Gaps = 25/250 (10%)

Query: 60  ATLLGLYLALFCFGWYALHFLVQSGISYCIMIIIGVENMHNYCFVFALGYLTVCQVTRVY 119
           A  +GL L LF  G + LH LV   +    +I     + H     +   YL   +   + 
Sbjct: 34  AAAVGLGLTLFTCGPHTLHSLVTI-LGTWALIQAQPCSCHALALAWTFSYLLFFRA--LS 90

Query: 120 IFDYGQYSADFSGPMMIITQKITSLACEIHDGMFRKDEELTSSQRDLAVRRM----PSLL 175
           +      +   +   +++T K+ SLA E+ D    + +E+ S         +    PSL+
Sbjct: 91  LLGLPTPTPFTNAVQLLLTLKLVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLM 150

Query: 176 EYLSYNCNFMGILAGPLCSYKDYITFIEGRSYHITQSGENGKEETQYERTEPSPNTAVVQ 235
           E LSY+  ++GI+ GP   Y+ Y+ ++E         G          R  P+P      
Sbjct: 151 ETLSYSYCYVGIMTGPFFRYRTYLDWLEQ-----PFPGAVPSLRPLLRRAWPAP------ 199

Query: 236 KLLVCGLSLLFHLTICTTLPVEYNIDEHFQATASWPTKIIYLYISLLAARPKYYFAWTLA 295
                 L  L  L      P+E   ++ F A    P ++ Y+     A R ++Y AW  A
Sbjct: 200 ------LFGLLFLLSSHLFPLEAVREDAFYA-RPLPARLFYMIPVFFAFRMRFYVAWIAA 252

Query: 296 DAINNAAGFG 305
           +    AAGFG
Sbjct: 253 ECGCIAAGFG 262


>gi|45439333 porcupine isoform C [Homo sapiens]
          Length = 455

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 79/369 (21%), Positives = 142/369 (38%), Gaps = 55/369 (14%)

Query: 32  QLFALLAAIWFRTYLHSSKTSSFIRHVVATLLGLYLALFCFGWYALHFLVQSGISYCIMI 91
           Q++ LLA       L      S+++H  +T+ G + +L+ F    + ++V   +   +++
Sbjct: 28  QIWLLLAICLACRLLWRLGLPSYLKHA-STVAGGFFSLYHFFQLHMVWVVLLSLLCYLVL 86

Query: 92  IIGVENMHNYCF--VFALGYLTVCQVTRVYIFDYGQYSADFSGPMMIITQKITSLACEIH 149
            +   + H   F  V  L YL + ++  V    + +      G  MI+  K  SL  ++ 
Sbjct: 87  FLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTWHK----MRGAQMIVAMKAVSLGFDLD 142

Query: 150 DGMFRKDEELTSSQRDLAVRRMPSLLEYLSYNCNFMGILAGPLCSYKDYITFIEGRSYHI 209
            G                V  +PS +E++ Y      I+ GP  S+  Y+  ++GR    
Sbjct: 143 RG---------------EVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSC 187

Query: 210 TQSGENGKEETQYERTEPSPNTAVVQKLLVCGLSLLFHLTICTTLPVEYNIDEHFQATAS 269
               +                   V + L   L  L   T        Y I  +      
Sbjct: 188 RWLQK-------------------VARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLR 228

Query: 270 WPTKIIYL--YISLLAARPKYYFAWTLADAINNAAGFGFRGYDENGAARWDLISNLRIQQ 327
             T + +L  Y S ++     YF   L++A    AG GF   +E     WDL  +  +  
Sbjct: 229 KGTMVRWLRAYESAVSFHFSNYFVGFLSEATATLAGAGFT--EEKDHLEWDLTVSKPLN- 285

Query: 328 IEMSTSFKMFLDNWNIQTALWLKRVCYERT----SFSPTIQTFILSAIWHGVYPGYYLTF 383
           +E+  S    + +WN+  + WL    ++      +FS  + T+  SA+ HG     +   
Sbjct: 286 VELPRSMVEVVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHG-----FSFH 340

Query: 384 LTGVLMTLA 392
           L  VL++LA
Sbjct: 341 LAAVLLSLA 349


>gi|45439331 porcupine isoform B [Homo sapiens]
          Length = 456

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 80/369 (21%), Positives = 149/369 (40%), Gaps = 54/369 (14%)

Query: 32  QLFALLAAIWFRTYLHSSKTSSFIRHVVATLLGLYLALFCFGWYALHFLVQSGISYCIMI 91
           Q++ LLA       L      S+++H  +T+ G + +L+ F    + ++V   +   +++
Sbjct: 28  QIWLLLAICLACRLLWRLGLPSYLKHA-STVAGGFFSLYHFFQLHMVWVVLLSLLCYLVL 86

Query: 92  IIGVENMHNYCF--VFALGYLTVCQVTRVYIFDYGQYSADFSGPMMIITQKITSLACEIH 149
            +   + H   F  V  L YL + ++  V    + +      G  MI+  K  SL  ++ 
Sbjct: 87  FLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTWHK----MRGAQMIVAMKAVSLGFDLD 142

Query: 150 DGMFRKDEELTSSQRDLAVRRMPSLLEYLSYNCNFMGILAGPLCSYKDYITFIEGRSYHI 209
            G                V  +PS +E++ Y      I+ GP  S+  Y+  ++GR    
Sbjct: 143 RG---------------EVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSC 187

Query: 210 TQSGENGKEETQYERTEPSPNTAVVQKLL-VCGLSLLFHLTICTTLPVEYN-IDEHFQAT 267
                        ++   S   A++  +L  C    LF   I    P+  + +  + +  
Sbjct: 188 RW----------LQKVARSLALALLCLVLSTCVGPYLFPYFI----PLNGDRLLRNKKRK 233

Query: 268 ASWPTKIIYLYISLLAARPKYYFAWTLADAINNAAGFGFRGYDENGAARWDLISNLRIQQ 327
           A W    +  Y S ++     YF   L++A    AG GF   +E     WDL  +  +  
Sbjct: 234 ARW----LRAYESAVSFHFSNYFVGFLSEATATLAGAGFT--EEKDHLEWDLTVSKPLN- 286

Query: 328 IEMSTSFKMFLDNWNIQTALWLKRVCYERT----SFSPTIQTFILSAIWHGVYPGYYLTF 383
           +E+  S    + +WN+  + WL    ++      +FS  + T+  SA+ HG     +   
Sbjct: 287 VELPRSMVEVVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHG-----FSFH 341

Query: 384 LTGVLMTLA 392
           L  VL++LA
Sbjct: 342 LAAVLLSLA 350


>gi|45439329 porcupine isoform A [Homo sapiens]
          Length = 450

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 76/367 (20%), Positives = 142/367 (38%), Gaps = 56/367 (15%)

Query: 32  QLFALLAAIWFRTYLHSSKTSSFIRHVVATLLGLYLALFCFGWYALHFLVQSGISYCIMI 91
           Q++ LLA       L      S+++H  +T+ G + +L+ F    + ++V   +   +++
Sbjct: 28  QIWLLLAICLACRLLWRLGLPSYLKHA-STVAGGFFSLYHFFQLHMVWVVLLSLLCYLVL 86

Query: 92  IIGVENMHNYCF--VFALGYLTVCQVTRVYIFDYGQYSADFSGPMMIITQKITSLACEIH 149
            +   + H   F  V  L YL + ++  V    + +      G  MI+  K  SL  ++ 
Sbjct: 87  FLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTWHK----MRGAQMIVAMKAVSLGFDLD 142

Query: 150 DGMFRKDEELTSSQRDLAVRRMPSLLEYLSYNCNFMGILAGPLCSYKDYITFIEGRSYHI 209
            G                V  +PS +E++ Y      I+ GP  S+  Y+  ++GR    
Sbjct: 143 RG---------------EVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSC 187

Query: 210 TQSGENGKEETQYERTEPSPNTAVVQKLLVCGLSLLFHLTICTTLPVEYNIDEHFQATAS 269
               +                  V + L +  L L+    +   L   +      +    
Sbjct: 188 RWLQK------------------VARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRK 229

Query: 270 WPTKIIYLYISLLAARPKYYFAWTLADAINNAAGFGFRGYDENGAARWDLISNLRIQQIE 329
           W    +  Y S ++     YF   L++A    AG GF   +E     WDL  +  +  +E
Sbjct: 230 W----LRAYESAVSFHFSNYFVGFLSEATATLAGAGFT--EEKDHLEWDLTVSKPLN-VE 282

Query: 330 MSTSFKMFLDNWNIQTALWLKRVCYERT----SFSPTIQTFILSAIWHGVYPGYYLTFLT 385
           +  S    + +WN+  + WL    ++      +FS  + T+  SA+ HG     +   L 
Sbjct: 283 LPRSMVEVVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHG-----FSFHLA 337

Query: 386 GVLMTLA 392
            VL++LA
Sbjct: 338 AVLLSLA 344


>gi|45439335 porcupine isoform D [Homo sapiens]
          Length = 461

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 78/368 (21%), Positives = 146/368 (39%), Gaps = 47/368 (12%)

Query: 32  QLFALLAAIWFRTYLHSSKTSSFIRHVVATLLGLYLALFCFGWYALHFLVQSGISYCIMI 91
           Q++ LLA       L      S+++H  +T+ G + +L+ F    + ++V   +   +++
Sbjct: 28  QIWLLLAICLACRLLWRLGLPSYLKHA-STVAGGFFSLYHFFQLHMVWVVLLSLLCYLVL 86

Query: 92  IIGVENMHNYCF--VFALGYLTVCQVTRVYIFDYGQYSADFSGPMMIITQKITSLACEIH 149
            +   + H   F  V  L YL + ++  V    + +      G  MI+  K  SL  ++ 
Sbjct: 87  FLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTWHK----MRGAQMIVAMKAVSLGFDLD 142

Query: 150 DGMFRKDEELTSSQRDLAVRRMPSLLEYLSYNCNFMGILAGPLCSYKDYITFIEGRSYHI 209
            G                V  +PS +E++ Y      I+ GP  S+  Y+  ++GR    
Sbjct: 143 RG---------------EVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSC 187

Query: 210 TQSGENGKEETQYERTEPSPNTAVVQKLL-VCGLSLLFHLTICTTLPVEYNIDEHFQATA 268
                        ++   S   A++  +L  C    LF   I   L  +  +    +   
Sbjct: 188 RW----------LQKVARSLALALLCLVLSTCVGPYLFPYFI--PLNGDRLLRNKKRKAR 235

Query: 269 SWPTKIIYLYISLLAARPKYYFAWTLADAINNAAGFGFRGYDENGAARWDLISNLRIQQI 328
               + +  Y S ++     YF   L++A    AG GF   +E     WDL  +  +  +
Sbjct: 236 GTMVRWLRAYESAVSFHFSNYFVGFLSEATATLAGAGFT--EEKDHLEWDLTVSKPLN-V 292

Query: 329 EMSTSFKMFLDNWNIQTALWLKRVCYERT----SFSPTIQTFILSAIWHGVYPGYYLTFL 384
           E+  S    + +WN+  + WL    ++      +FS  + T+  SA+ HG     +   L
Sbjct: 293 ELPRSMVEVVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHG-----FSFHL 347

Query: 385 TGVLMTLA 392
             VL++LA
Sbjct: 348 AAVLLSLA 355


>gi|45439337 porcupine isoform E [Homo sapiens]
          Length = 379

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 57/265 (21%), Positives = 99/265 (37%), Gaps = 49/265 (18%)

Query: 132 GPMMIITQKITSLACEIHDGMFRKDEELTSSQRDLAVRRMPSLLEYLSYNCNFMGILAGP 191
           G  MI+  K  SL  ++  G                V  +PS +E++ Y      I+ GP
Sbjct: 54  GAQMIVAMKAVSLGFDLDRG---------------EVGTVPSPVEFMGYLYFVGTIVFGP 98

Query: 192 LCSYKDYITFIEGRSYHITQSGENGKEETQYERTEPSPNTAVVQKLLVCGLSLLFHLTIC 251
             S+  Y+  ++GR        +                  V + L +  L L+    + 
Sbjct: 99  WISFHSYLQAVQGRPLSCRWLQK------------------VARSLALALLCLVLSTCVG 140

Query: 252 TTLPVEYNIDEHFQATASWPTKIIYLYISLLAARPKYYFAWTLADAINNAAGFGFRGYDE 311
             L   +      +    W    +  Y S ++     YF   L++A    AG GF   +E
Sbjct: 141 PYLFPYFIPLNGDRLLRKW----LRAYESAVSFHFSNYFVGFLSEATATLAGAGFT--EE 194

Query: 312 NGAARWDLISNLRIQQIEMSTSFKMFLDNWNIQTALWLKRVCYERT----SFSPTIQTFI 367
                WDL  +  +  +E+  S    + +WN+  + WL    ++      +FS  + T+ 
Sbjct: 195 KDHLEWDLTVSKPLN-VELPRSMVEVVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYA 253

Query: 368 LSAIWHGVYPGYYLTFLTGVLMTLA 392
            SA+ HG     +   L  VL++LA
Sbjct: 254 ASALLHG-----FSFHLAAVLLSLA 273


>gi|125660451 MAS-related GPR, member X1 [Homo sapiens]
          Length = 322

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 34/134 (25%), Positives = 56/134 (41%), Gaps = 32/134 (23%)

Query: 352 VCYERTSFSPTIQTFILSAIWHGVYPGYYLTFLTGVLMTLAARAMRNNFRHYFIEPSQL- 410
           +CY++T  S T+ T I+S +         LT    VL  L  R  RN F  Y +  +   
Sbjct: 22  LCYKQT-LSLTVLTCIVSLVG--------LTGNAVVLWLLGCRMRRNAFSIYILNLAAAD 72

Query: 411 ------KLFYDVITWIVTQVAISYTVVPFVLLSIKPSLTFYSS-------------WYYC 451
                 +L Y ++++I     IS  + P ++ S    L+F S+             WY C
Sbjct: 73  FLFLSGRLIYSLLSFISIPHTISKILYPVMMFSYFAGLSFLSAVSTERCLSVLWPIWYRC 132

Query: 452 ---LHILGILVLLL 462
               H+  ++ +LL
Sbjct: 133 HRPTHLSAVVCVLL 146


>gi|154275767 ADAMTS-like 1 isoform 4 precursor [Homo sapiens]
          Length = 1762

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 18/59 (30%), Positives = 30/59 (50%)

Query: 231 TAVVQKLLVCGLSLLFHLTICTTLPVEYNIDEHFQATASWPTKIIYLYISLLAARPKYY 289
           +A+ +K+L  GLS + + T+C  LP   +I     AT + P +    +   +AA  K Y
Sbjct: 812 SAICRKMLKTGLSTVVNSTLCPPLPFSSSIRPCMLATCARPGRPSTKHSPHIAAARKVY 870


>gi|4557859 somatostatin receptor 2 [Homo sapiens]
          Length = 369

 Score = 29.3 bits (64), Expect = 9.1
 Identities = 23/108 (21%), Positives = 43/108 (39%), Gaps = 3/108 (2%)

Query: 30  VCQLFALLAAIWFRTYLHSSKTSSFIRHVVATLLGLYLALFCFGWYALHFLVQSGISYCI 89
           +C LF ++        + SSK     + V   ++ + +A+F F W   +    S +S  I
Sbjct: 226 LCYLFIIIKVKSSGIRVGSSKRKKSEKKVTR-MVSIVVAVFIFCWLPFYIFNVSSVSMAI 284

Query: 90  MIIIGVENMHNYCFVFALGYLTVCQVTRVYIFDYGQYSADFSGPMMII 137
                ++ M  + FV  L Y   C    +Y F    +   F   + ++
Sbjct: 285 SPTPALKGM--FDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLV 330


>gi|170932464 Yip1 interacting factor homolog [Homo sapiens]
          Length = 293

 Score = 29.3 bits (64), Expect = 9.1
 Identities = 16/38 (42%), Positives = 19/38 (50%)

Query: 55  IRHVVATLLGLYLALFCFGWYALHFLVQSGISYCIMII 92
           +  V+A LLGLYLA         H L  SG  Y  MI+
Sbjct: 180 VMEVLALLLGLYLATVRSDLSTFHLLAYSGYKYVGMIL 217


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.137    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,204,808
Number of Sequences: 37866
Number of extensions: 741264
Number of successful extensions: 2208
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2172
Number of HSP's gapped (non-prelim): 24
length of query: 520
length of database: 18,247,518
effective HSP length: 107
effective length of query: 413
effective length of database: 14,195,856
effective search space: 5862888528
effective search space used: 5862888528
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.