Guide to the Human Genome
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Search of human proteins with 40353757

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40353757 brain and reproductive organ-expressed (TNFRSF1A
modulator) isoform 2 [Homo sapiens]
         (383 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40353757 brain and reproductive organ-expressed (TNFRSF1A mod...   795   0.0  
gi|40353761 brain and reproductive organ-expressed (TNFRSF1A mod...   795   0.0  
gi|40353755 brain and reproductive organ-expressed (TNFRSF1A mod...   754   0.0  
gi|40353759 brain and reproductive organ-expressed (TNFRSF1A mod...   754   0.0  
gi|21361171 brain and reproductive organ-expressed (TNFRSF1A mod...   754   0.0  
gi|94681049 hypothetical protein LOC80217 [Homo sapiens]               30   2.8  
gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptid...    30   3.6  
gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]      30   3.6  
gi|27894339 keratin 23 [Homo sapiens]                                  30   4.8  
gi|148886692 FAT tumor suppressor homolog 3 [Homo sapiens]             30   4.8  
gi|4826964 UV excision repair protein RAD23 homolog A [Homo sapi...    29   8.1  

>gi|40353757 brain and reproductive organ-expressed (TNFRSF1A
           modulator) isoform 2 [Homo sapiens]
          Length = 383

 Score =  795 bits (2052), Expect = 0.0
 Identities = 383/383 (100%), Positives = 383/383 (100%)

Query: 1   MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHI 60
           MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHI
Sbjct: 1   MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHI 60

Query: 61  PYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQNLASWNPSNPECLLLVVKEL 120
           PYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQNLASWNPSNPECLLLVVKEL
Sbjct: 61  PYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQNLASWNPSNPECLLLVVKEL 120

Query: 121 VQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVD 180
           VQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVD
Sbjct: 121 VQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVD 180

Query: 181 FSNIPTYLLKDVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAF 240
           FSNIPTYLLKDVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAF
Sbjct: 181 FSNIPTYLLKDVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAF 240

Query: 241 PGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLSHFGTGVVEYDAEGFTKLTLL 300
           PGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLSHFGTGVVEYDAEGFTKLTLL
Sbjct: 241 PGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLSHFGTGVVEYDAEGFTKLTLL 300

Query: 301 LMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAK 360
           LMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAK
Sbjct: 301 LMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAK 360

Query: 361 RAKAYFKTFVPQFQEAAFANGKL 383
           RAKAYFKTFVPQFQEAAFANGKL
Sbjct: 361 RAKAYFKTFVPQFQEAAFANGKL 383


>gi|40353761 brain and reproductive organ-expressed (TNFRSF1A
           modulator) isoform 2 [Homo sapiens]
          Length = 383

 Score =  795 bits (2052), Expect = 0.0
 Identities = 383/383 (100%), Positives = 383/383 (100%)

Query: 1   MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHI 60
           MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHI
Sbjct: 1   MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHI 60

Query: 61  PYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQNLASWNPSNPECLLLVVKEL 120
           PYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQNLASWNPSNPECLLLVVKEL
Sbjct: 61  PYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQNLASWNPSNPECLLLVVKEL 120

Query: 121 VQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVD 180
           VQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVD
Sbjct: 121 VQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVD 180

Query: 181 FSNIPTYLLKDVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAF 240
           FSNIPTYLLKDVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAF
Sbjct: 181 FSNIPTYLLKDVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAF 240

Query: 241 PGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLSHFGTGVVEYDAEGFTKLTLL 300
           PGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLSHFGTGVVEYDAEGFTKLTLL
Sbjct: 241 PGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLSHFGTGVVEYDAEGFTKLTLL 300

Query: 301 LMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAK 360
           LMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAK
Sbjct: 301 LMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAK 360

Query: 361 RAKAYFKTFVPQFQEAAFANGKL 383
           RAKAYFKTFVPQFQEAAFANGKL
Sbjct: 361 RAKAYFKTFVPQFQEAAFANGKL 383


>gi|40353755 brain and reproductive organ-expressed (TNFRSF1A
           modulator) isoform 3 [Homo sapiens]
          Length = 376

 Score =  754 bits (1948), Expect = 0.0
 Identities = 363/363 (100%), Positives = 363/363 (100%)

Query: 1   MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHI 60
           MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHI
Sbjct: 1   MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHI 60

Query: 61  PYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQNLASWNPSNPECLLLVVKEL 120
           PYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQNLASWNPSNPECLLLVVKEL
Sbjct: 61  PYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQNLASWNPSNPECLLLVVKEL 120

Query: 121 VQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVD 180
           VQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVD
Sbjct: 121 VQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVD 180

Query: 181 FSNIPTYLLKDVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAF 240
           FSNIPTYLLKDVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAF
Sbjct: 181 FSNIPTYLLKDVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAF 240

Query: 241 PGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLSHFGTGVVEYDAEGFTKLTLL 300
           PGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLSHFGTGVVEYDAEGFTKLTLL
Sbjct: 241 PGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLSHFGTGVVEYDAEGFTKLTLL 300

Query: 301 LMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAK 360
           LMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAK
Sbjct: 301 LMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAK 360

Query: 361 RAK 363
           RAK
Sbjct: 361 RAK 363


>gi|40353759 brain and reproductive organ-expressed (TNFRSF1A
           modulator) isoform 3 [Homo sapiens]
          Length = 376

 Score =  754 bits (1948), Expect = 0.0
 Identities = 363/363 (100%), Positives = 363/363 (100%)

Query: 1   MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHI 60
           MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHI
Sbjct: 1   MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHI 60

Query: 61  PYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQNLASWNPSNPECLLLVVKEL 120
           PYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQNLASWNPSNPECLLLVVKEL
Sbjct: 61  PYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQNLASWNPSNPECLLLVVKEL 120

Query: 121 VQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVD 180
           VQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVD
Sbjct: 121 VQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVD 180

Query: 181 FSNIPTYLLKDVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAF 240
           FSNIPTYLLKDVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAF
Sbjct: 181 FSNIPTYLLKDVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAF 240

Query: 241 PGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLSHFGTGVVEYDAEGFTKLTLL 300
           PGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLSHFGTGVVEYDAEGFTKLTLL
Sbjct: 241 PGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLSHFGTGVVEYDAEGFTKLTLL 300

Query: 301 LMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAK 360
           LMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAK
Sbjct: 301 LMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAK 360

Query: 361 RAK 363
           RAK
Sbjct: 361 RAK 363


>gi|21361171 brain and reproductive organ-expressed (TNFRSF1A
           modulator) isoform 1 [Homo sapiens]
          Length = 415

 Score =  754 bits (1948), Expect = 0.0
 Identities = 363/363 (100%), Positives = 363/363 (100%)

Query: 1   MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHI 60
           MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHI
Sbjct: 1   MSPEVALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHI 60

Query: 61  PYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQNLASWNPSNPECLLLVVKEL 120
           PYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQNLASWNPSNPECLLLVVKEL
Sbjct: 61  PYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQNLASWNPSNPECLLLVVKEL 120

Query: 121 VQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVD 180
           VQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVD
Sbjct: 121 VQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVD 180

Query: 181 FSNIPTYLLKDVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAF 240
           FSNIPTYLLKDVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAF
Sbjct: 181 FSNIPTYLLKDVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAF 240

Query: 241 PGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLSHFGTGVVEYDAEGFTKLTLL 300
           PGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLSHFGTGVVEYDAEGFTKLTLL
Sbjct: 241 PGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLSHFGTGVVEYDAEGFTKLTLL 300

Query: 301 LMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAK 360
           LMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAK
Sbjct: 301 LMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAK 360

Query: 361 RAK 363
           RAK
Sbjct: 361 RAK 363


>gi|94681049 hypothetical protein LOC80217 [Homo sapiens]
          Length = 1665

 Score = 30.4 bits (67), Expect = 2.8
 Identities = 14/30 (46%), Positives = 19/30 (63%)

Query: 179 VDFSNIPTYLLKDVNEDPGEDVALLSVSFE 208
           V +SN+P YLL  ++ D G D +LLS   E
Sbjct: 969 VKYSNLPNYLLGSLSTDFGVDTSLLSSQLE 998


>gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptide
           [Homo sapiens]
          Length = 1686

 Score = 30.0 bits (66), Expect = 3.6
 Identities = 22/76 (28%), Positives = 35/76 (46%), Gaps = 6/76 (7%)

Query: 303 WKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAKRA 362
           +K+F +L+  D  + FP     L  +SV H T  G + +Q+  + P     D N+  K  
Sbjct: 732 YKNFFYLIKWDELIIFPIQISQLPLESVLHLTLFG-ILNQSSGSSP-----DSNKQRKGP 785

Query: 363 KAYFKTFVPQFQEAAF 378
           +A  K  +P F    F
Sbjct: 786 EALGKVSLPLFDFKRF 801


>gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]
          Length = 4490

 Score = 30.0 bits (66), Expect = 3.6
 Identities = 20/78 (25%), Positives = 34/78 (43%), Gaps = 3/78 (3%)

Query: 84  FIFGEDAEFLPDPSALQNLASWNPSNPECLLLVVKELVQQYHQFQCSRLRESSRLMFEYQ 143
           F+     + L    ALQ L  +   N  CL L +   +++  Q+  + L  + +L   Y 
Sbjct: 443 FMNSSFGKILSSQQALQLLQRFQKLNIPCLGLEINHTIERILQYYVAELDATKKL---YH 499

Query: 144 TLLEEPQYGENMEIYAGK 161
           +  ++P    NM   AGK
Sbjct: 500 SQKDDPPLARNMPPIAGK 517


>gi|27894339 keratin 23 [Homo sapiens]
          Length = 422

 Score = 29.6 bits (65), Expect = 4.8
 Identities = 17/50 (34%), Positives = 24/50 (48%)

Query: 97  SALQNLASWNPSNPECLLLVVKELVQQYHQFQCSRLRESSRLMFEYQTLL 146
           SAL+N+ S   S   C L  ++E++  Y +       E  R   EYQ LL
Sbjct: 309 SALENMLSETQSRYSCKLQDMQEIISHYEEELTQLRHELERQNNEYQVLL 358


>gi|148886692 FAT tumor suppressor homolog 3 [Homo sapiens]
          Length = 4557

 Score = 29.6 bits (65), Expect = 4.8
 Identities = 24/90 (26%), Positives = 37/90 (41%), Gaps = 5/90 (5%)

Query: 148  EPQYGENMEIYAGKKNNWTGEF-----SARFLLKLPVDFSNIPTYLLKDVNEDPGEDVAL 202
            +P  G   ++     N++ G F     S    L   +D+     Y L    +D G  V+L
Sbjct: 962  DPDLGLGGQVRYSLVNDYNGRFEIDKASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVSL 1021

Query: 203  LSVSFEDTEATQVYPKLYLSPRIEHALGGS 232
             SVSF + E   V   L+     + A+ GS
Sbjct: 1022 SSVSFVEVEVVDVNENLHTPYFPDFAVVGS 1051


>gi|4826964 UV excision repair protein RAD23 homolog A [Homo
           sapiens]
          Length = 363

 Score = 28.9 bits (63), Expect = 8.1
 Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 5/76 (6%)

Query: 75  AQYPELPPDFIFGEDA-EFLPDPSALQNLASWNPSNPECLLLVVKELVQQYHQFQCSRLR 133
           +Q  E P     GE+  EFL D    QN+      NP  L  ++++L Q+  Q     L+
Sbjct: 216 SQVSEQPATEAAGENPLEFLRDQPQFQNMRQVIQQNPALLPALLQQLGQENPQL----LQ 271

Query: 134 ESSRLMFEYQTLLEEP 149
           + SR   ++  +L EP
Sbjct: 272 QISRHQEQFIQMLNEP 287


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,891,105
Number of Sequences: 37866
Number of extensions: 756380
Number of successful extensions: 1408
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1400
Number of HSP's gapped (non-prelim): 12
length of query: 383
length of database: 18,247,518
effective HSP length: 104
effective length of query: 279
effective length of database: 14,309,454
effective search space: 3992337666
effective search space used: 3992337666
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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