Search of human proteins with 40316946

Search of human proteins with 40316946

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40316946 ADP-ribosylhydrolase like 1 isoform 2 [Homo
sapiens]
         (272 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40316946 ADP-ribosylhydrolase like 1 isoform 2 [Homo sapiens]      573   e-164
gi|21702735 ADP-ribosylhydrolase like 1 isoform 1 [Homo sapiens]      573   e-164
gi|4557263 ADP-ribosylarginine hydrolase [Homo sapiens]               250   8e-67
gi|8923417 ADP-ribosylhydrolase like 2 [Homo sapiens]                  50   2e-06
gi|41352061 metalloprotease 1 [Homo sapiens]                           32   0.45 
gi|4885487 myeloid leukemia factor 2 [Homo sapiens]                    30   2.9  
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...    28   6.5  
gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapi...    28   6.5  
gi|226823326 methenyltetrahydrofolate synthetase domain containi...    28   8.5  
gi|226823324 methenyltetrahydrofolate synthetase domain containi...    28   8.5  
gi|226823322 methenyltetrahydrofolate synthetase domain containi...    28   8.5  
gi|226823319 methenyltetrahydrofolate synthetase domain containi...    28   8.5  
gi|116875838 methenyltetrahydrofolate synthetase domain containi...    28   8.5  

>gi|40316946 ADP-ribosylhydrolase like 1 isoform 2 [Homo sapiens]
          Length = 272

 Score =  573 bits (1477), Expect = e-164
 Identities = 272/272 (100%), Positives = 272/272 (100%)

Query: 1   MVRCYVEIVEKLPERRPDPATIEGCAQLKPNNYLLAWHTPFNEKGSGFGAATKAMCIGLR 60
           MVRCYVEIVEKLPERRPDPATIEGCAQLKPNNYLLAWHTPFNEKGSGFGAATKAMCIGLR
Sbjct: 1   MVRCYVEIVEKLPERRPDPATIEGCAQLKPNNYLLAWHTPFNEKGSGFGAATKAMCIGLR 60

Query: 61  YWKPERLETLIEVSVECGRMTHNHPTGFLGSLCTALFVSFAAQGKPLVQWGRDMLRAVPL 120
           YWKPERLETLIEVSVECGRMTHNHPTGFLGSLCTALFVSFAAQGKPLVQWGRDMLRAVPL
Sbjct: 61  YWKPERLETLIEVSVECGRMTHNHPTGFLGSLCTALFVSFAAQGKPLVQWGRDMLRAVPL 120

Query: 121 AEEYCRKTIRHTAEYQEHWFYFEAKWQFYLEERKISKDSENKAIFPDNYDAEEREKTYRK 180
           AEEYCRKTIRHTAEYQEHWFYFEAKWQFYLEERKISKDSENKAIFPDNYDAEEREKTYRK
Sbjct: 121 AEEYCRKTIRHTAEYQEHWFYFEAKWQFYLEERKISKDSENKAIFPDNYDAEEREKTYRK 180

Query: 181 WSSEGRGGRRGHDAPMIAYDALLAAGNSWTELCHRAMFHGGESAATGTIAGCLFGLLYGL 240
           WSSEGRGGRRGHDAPMIAYDALLAAGNSWTELCHRAMFHGGESAATGTIAGCLFGLLYGL
Sbjct: 181 WSSEGRGGRRGHDAPMIAYDALLAAGNSWTELCHRAMFHGGESAATGTIAGCLFGLLYGL 240

Query: 241 DLVPKGLYQDLEDKEKLEDLGAALYRLSTEEK 272
           DLVPKGLYQDLEDKEKLEDLGAALYRLSTEEK
Sbjct: 241 DLVPKGLYQDLEDKEKLEDLGAALYRLSTEEK 272


>gi|21702735 ADP-ribosylhydrolase like 1 isoform 1 [Homo sapiens]
          Length = 354

 Score =  573 bits (1477), Expect = e-164
 Identities = 272/272 (100%), Positives = 272/272 (100%)

Query: 1   MVRCYVEIVEKLPERRPDPATIEGCAQLKPNNYLLAWHTPFNEKGSGFGAATKAMCIGLR 60
           MVRCYVEIVEKLPERRPDPATIEGCAQLKPNNYLLAWHTPFNEKGSGFGAATKAMCIGLR
Sbjct: 83  MVRCYVEIVEKLPERRPDPATIEGCAQLKPNNYLLAWHTPFNEKGSGFGAATKAMCIGLR 142

Query: 61  YWKPERLETLIEVSVECGRMTHNHPTGFLGSLCTALFVSFAAQGKPLVQWGRDMLRAVPL 120
           YWKPERLETLIEVSVECGRMTHNHPTGFLGSLCTALFVSFAAQGKPLVQWGRDMLRAVPL
Sbjct: 143 YWKPERLETLIEVSVECGRMTHNHPTGFLGSLCTALFVSFAAQGKPLVQWGRDMLRAVPL 202

Query: 121 AEEYCRKTIRHTAEYQEHWFYFEAKWQFYLEERKISKDSENKAIFPDNYDAEEREKTYRK 180
           AEEYCRKTIRHTAEYQEHWFYFEAKWQFYLEERKISKDSENKAIFPDNYDAEEREKTYRK
Sbjct: 203 AEEYCRKTIRHTAEYQEHWFYFEAKWQFYLEERKISKDSENKAIFPDNYDAEEREKTYRK 262

Query: 181 WSSEGRGGRRGHDAPMIAYDALLAAGNSWTELCHRAMFHGGESAATGTIAGCLFGLLYGL 240
           WSSEGRGGRRGHDAPMIAYDALLAAGNSWTELCHRAMFHGGESAATGTIAGCLFGLLYGL
Sbjct: 263 WSSEGRGGRRGHDAPMIAYDALLAAGNSWTELCHRAMFHGGESAATGTIAGCLFGLLYGL 322

Query: 241 DLVPKGLYQDLEDKEKLEDLGAALYRLSTEEK 272
           DLVPKGLYQDLEDKEKLEDLGAALYRLSTEEK
Sbjct: 323 DLVPKGLYQDLEDKEKLEDLGAALYRLSTEEK 354


>gi|4557263 ADP-ribosylarginine hydrolase [Homo sapiens]
          Length = 357

 Score =  250 bits (639), Expect = 8e-67
 Identities = 122/271 (45%), Positives = 175/271 (64%), Gaps = 2/271 (0%)

Query: 1   MVRCYVEIVEKLPERRPDPATIEGCAQLKPNNYLLAWHTPFNEKGSGFGAATKAMCIGLR 60
           + + Y + +E +  R P  A++    QLKP      W  PFN    G GAA +AMCIGLR
Sbjct: 83  LAKHYQDCMEDMDGRAPGGASVHNAMQLKPGKPN-GWRIPFNSHEGGCGAAMRAMCIGLR 141

Query: 61  YWKPERLETLIEVSVECGRMTHNHPTGFLGSLCTALFVSFAAQGKPLVQWGRDMLRAVPL 120
           +    +L+TLI+VS+E GRMTH+HPTG+LG+L +ALF ++A   +P +QWG+ ++  +P 
Sbjct: 142 FPHHSQLDTLIQVSIESGRMTHHHPTGYLGALASALFTAYAVNSRPPLQWGKGLMELLPE 201

Query: 121 AEEYCRKTIRHTAEYQEHWFYFEAKWQFYLEERKISKDSENKAIFPDNYDAEEREKTYRK 180
           A++Y  ++     E  +HW YF+ KW+ YL+ R I  D E+   FP+++  +ER++ Y  
Sbjct: 202 AKKYIVQSGYFVEENLQHWSYFQTKWENYLKLRGI-LDGESAPTFPESFGVKERDQFYTS 260

Query: 181 WSSEGRGGRRGHDAPMIAYDALLAAGNSWTELCHRAMFHGGESAATGTIAGCLFGLLYGL 240
            S  G GG  GHDAPMIAYDA+LAAG+SW EL HRA FHGG+S +T  IAGC +G++YG 
Sbjct: 261 LSYSGWGGSSGHDAPMIAYDAVLAAGDSWKELAHRAFFHGGDSDSTAAIAGCWWGVMYGF 320

Query: 241 DLVPKGLYQDLEDKEKLEDLGAALYRLSTEE 271
             V    Y+ LE + +LE+   ALY L ++E
Sbjct: 321 KGVSPSNYEKLEYRNRLEETARALYSLGSKE 351


>gi|8923417 ADP-ribosylhydrolase like 2 [Homo sapiens]
          Length = 363

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 56/237 (23%), Positives = 91/237 (38%), Gaps = 30/237 (12%)

Query: 41  FNEKGS-GFGAATKAMCIGLRYWKPERLETLIEVSVECGRMTHNHPTGFLGSLCTALFVS 99
           FN KGS G G A +   I L Y   + ++    +S +   +TH    G+ G++  AL V 
Sbjct: 143 FNGKGSYGNGGAMRVAGISLAYSSVQDVQKFARLSAQ---LTHASSLGYNGAILQALAVH 199

Query: 100 FAAQGKPLVQWGRDMLRAVPLAEEYCRKTIRHTAEYQEHWFYFEAKWQFYLEERKISKDS 159
            A QG+               +E + ++ + H  + +          +  +EER  S   
Sbjct: 200 LALQGESS-------------SEHFLKQLLGHMEDLEGDAQSVLDARELGMEERPYSSRL 246

Query: 160 ENKAIFPDNYDAEEREKTYRKWSSEGRGGRRGHDAPMIAYDALL---------AAGNSWT 210
           +      D       E      S  G G       P   Y  L          +A NS  
Sbjct: 247 KKIGELLDQASVTREEVV----SELGNGIAAFESVPTAIYCFLRCMEPDPEIPSAFNSLQ 302

Query: 211 ELCHRAMFHGGESAATGTIAGCLFGLLYGLDLVPKGLYQDLEDKEKLEDLGAALYRL 267
                ++  GG++    T+AG + G  YG+D VP+   Q  E  E+ + L  +L+R+
Sbjct: 303 RTLIYSISLGGDTDTIATMAGAIAGAYYGMDQVPESWQQSCEGYEETDILAQSLHRV 359


>gi|41352061 metalloprotease 1 [Homo sapiens]
          Length = 1037

 Score = 32.3 bits (72), Expect = 0.45
 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 7/68 (10%)

Query: 7   EIVEKLPERRPDPATIEGCAQLKPNNYLLAWHTPFNEKGSGFGAATKAMCIGL----RYW 62
           E +  +P   PD A+++  A+L    +L   HT   EKG  +G   K    G+     Y 
Sbjct: 868 ECIRTVPYTDPDHASLKILARLMTAKFL---HTEIREKGGAYGGGAKLSHNGIFTLYSYR 924

Query: 63  KPERLETL 70
            P  +ETL
Sbjct: 925 DPNTIETL 932


>gi|4885487 myeloid leukemia factor 2 [Homo sapiens]
          Length = 248

 Score = 29.6 bits (65), Expect = 2.9
 Identities = 32/144 (22%), Positives = 52/144 (36%), Gaps = 23/144 (15%)

Query: 78  GRMTHNHPTGFLGSLCTALFVSFA--AQGKPLVQWGRDMLRAVPLAEEYCRKTIR----- 130
           G M H    G   +  ++  +S++    G P V      +R+ P      R+T+R     
Sbjct: 88  GNMEHMTAGGNCQTFSSSTVISYSNTGDGAPKVYQETSEMRSAPGGIRETRRTVRDSDSG 147

Query: 131 -------HTAEYQEHWFYFEAKWQFYLEERK---ISKDSENKAIFPDNYDAE------ER 174
                  H    + H        +   +E +   I+ D    A F D +  E      +R
Sbjct: 148 LEQMSIGHHIRDRAHILQRSRNHRTGDQEERQDYINLDESEAAAFDDEWRRETSRFRQQR 207

Query: 175 EKTYRKWSSEGRGGRRGHDAPMIA 198
              +R+  S G GGRR    P +A
Sbjct: 208 PLEFRRLESSGAGGRRAEGPPRLA 231


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 5/65 (7%)

Query: 156 SKDSENKAIFPDNYDAEEREKTYRKWSSEGRGGR-RGHDAPMIAYDALLAAGNSWTELCH 214
           S+ S   +  P+   AEE  +T  +  S GRGGR RG   P  A    +AAG+    LC 
Sbjct: 17  SRRSSTVSRAPERRPAEELNRTGPEGYSVGRGGRWRGTSRPPEA----VAAGHEELPLCF 72

Query: 215 RAMFH 219
               H
Sbjct: 73  ALKSH 77


>gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo
           sapiens]
          Length = 1227

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 17/69 (24%), Positives = 32/69 (46%), Gaps = 5/69 (7%)

Query: 120 LAEEYCRKTIRHTAEYQEHWFYFEAKWQFYLEERKISKDSENKAIFPDNYDAEEREKTYR 179
           ++EE+  ++ +   E +EH  Y  +K     EE+   K+      +    D +ER+++  
Sbjct: 124 VSEEFWERSRQRERERREHGVYASSK-----EEKDWKKEKSRDRDYDRKRDRDERDRSRH 178

Query: 180 KWSSEGRGG 188
              SE  GG
Sbjct: 179 SSRSERDGG 187


>gi|226823326 methenyltetrahydrofolate synthetase domain containing
           isoform 5 [Homo sapiens]
          Length = 363

 Score = 28.1 bits (61), Expect = 8.5
 Identities = 16/47 (34%), Positives = 20/47 (42%)

Query: 208 SWTELCHRAMFHGGESAATGTIAGCLFGLLYGLDLVPKGLYQDLEDK 254
           +W     RA  H  +SAA      CL GL  G D +   L +   DK
Sbjct: 317 TWQGPRRRAFLHYPDSAAAQQAVSCLQGLRLGTDTLRVALARQQRDK 363


>gi|226823324 methenyltetrahydrofolate synthetase domain containing
           isoform 4 [Homo sapiens]
          Length = 382

 Score = 28.1 bits (61), Expect = 8.5
 Identities = 16/47 (34%), Positives = 20/47 (42%)

Query: 208 SWTELCHRAMFHGGESAATGTIAGCLFGLLYGLDLVPKGLYQDLEDK 254
           +W     RA  H  +SAA      CL GL  G D +   L +   DK
Sbjct: 336 TWQGPRRRAFLHYPDSAAAQQAVSCLQGLRLGTDTLRVALARQQRDK 382


>gi|226823322 methenyltetrahydrofolate synthetase domain containing
           isoform 2 [Homo sapiens]
          Length = 383

 Score = 28.1 bits (61), Expect = 8.5
 Identities = 16/47 (34%), Positives = 20/47 (42%)

Query: 208 SWTELCHRAMFHGGESAATGTIAGCLFGLLYGLDLVPKGLYQDLEDK 254
           +W     RA  H  +SAA      CL GL  G D +   L +   DK
Sbjct: 337 TWQGPRRRAFLHYPDSAAAQQAVSCLQGLRLGTDTLRVALARQQRDK 383


>gi|226823319 methenyltetrahydrofolate synthetase domain containing
           isoform 1 [Homo sapiens]
          Length = 383

 Score = 28.1 bits (61), Expect = 8.5
 Identities = 16/47 (34%), Positives = 20/47 (42%)

Query: 208 SWTELCHRAMFHGGESAATGTIAGCLFGLLYGLDLVPKGLYQDLEDK 254
           +W     RA  H  +SAA      CL GL  G D +   L +   DK
Sbjct: 337 TWQGPRRRAFLHYPDSAAAQQAVSCLQGLRLGTDTLRVALARQQRDK 383


>gi|116875838 methenyltetrahydrofolate synthetase domain containing
           isoform 3 [Homo sapiens]
          Length = 382

 Score = 28.1 bits (61), Expect = 8.5
 Identities = 16/47 (34%), Positives = 20/47 (42%)

Query: 208 SWTELCHRAMFHGGESAATGTIAGCLFGLLYGLDLVPKGLYQDLEDK 254
           +W     RA  H  +SAA      CL GL  G D +   L +   DK
Sbjct: 336 TWQGPRRRAFLHYPDSAAAQQAVSCLQGLRLGTDTLRVALARQQRDK 382


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.435 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,432,413
Number of Sequences: 37866
Number of extensions: 522816
Number of successful extensions: 1177
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1165
Number of HSP's gapped (non-prelim): 13
length of query: 272
length of database: 18,247,518
effective HSP length: 101
effective length of query: 171
effective length of database: 14,423,052
effective search space: 2466341892
effective search space used: 2466341892
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.