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Search of human proteins with 39725934
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|39725934 serine (or cysteine) proteinase inhibitor, clade F
(alpha-2 antiplasmin, pigment epithelium derived factor), member 1
[Homo sapiens]
(418 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|39725934 serine (or cysteine) proteinase inhibitor, clade F (... 825 0.0
gi|115583663 alpha-2-plasmin inhibitor [Homo sapiens] 173 2e-43
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom... 157 2e-38
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom... 157 2e-38
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom... 157 2e-38
gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom... 157 2e-38
gi|189163534 serine proteinase inhibitor, clade A, member 1 [Hom... 157 2e-38
gi|189163532 serine proteinase inhibitor, clade A, member 1 [Hom... 157 2e-38
gi|189163530 serine proteinase inhibitor, clade A, member 1 [Hom... 157 2e-38
gi|189163528 serine proteinase inhibitor, clade A, member 1 [Hom... 157 2e-38
gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo... 157 2e-38
gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo... 157 2e-38
gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo... 157 2e-38
gi|73858564 corticosteroid binding globulin precursor [Homo sapi... 148 8e-36
gi|73858570 serpin peptidase inhibitor, clade G, member 1 precur... 147 2e-35
gi|73858568 serpin peptidase inhibitor, clade G, member 1 precur... 147 2e-35
gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur... 145 7e-35
gi|122937297 serpin peptidase inhibitor, clade A (alpha-1 antipr... 142 6e-34
gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ... 139 5e-33
gi|21361302 serine (or cysteine) proteinase inhibitor, clade A (... 138 8e-33
gi|154759291 serine (or cysteine) proteinase inhibitor, clade A ... 137 1e-32
gi|7705879 serine (or cysteine) proteinase inhibitor, clade A (a... 137 1e-32
gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (... 137 1e-32
gi|27777657 serine (or cysteine) proteinase inhibitor, clade A (... 137 2e-32
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ... 135 9e-32
gi|73858566 heparin cofactor II precursor [Homo sapiens] 133 3e-31
gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,... 132 6e-31
gi|32454741 serine (or cysteine) proteinase inhibitor, clade H, ... 128 1e-29
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o... 128 1e-29
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (... 125 9e-29
>gi|39725934 serine (or cysteine) proteinase inhibitor, clade F
(alpha-2 antiplasmin, pigment epithelium derived
factor), member 1 [Homo sapiens]
Length = 418
Score = 825 bits (2131), Expect = 0.0
Identities = 418/418 (100%), Positives = 418/418 (100%)
Query: 1 MQALVLLLCIGALLGHSSCQNPASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSN 60
MQALVLLLCIGALLGHSSCQNPASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSN
Sbjct: 1 MQALVLLLCIGALLGHSSCQNPASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSN 60
Query: 61 FGYDLYRVRSSTSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPDIHG 120
FGYDLYRVRSSTSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPDIHG
Sbjct: 61 FGYDLYRVRSSTSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPDIHG 120
Query: 121 TYKELLDTVTAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLTGNPRLDLQEI 180
TYKELLDTVTAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLTGNPRLDLQEI
Sbjct: 121 TYKELLDTVTAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLTGNPRLDLQEI 180
Query: 181 NNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVR 240
NNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVR
Sbjct: 181 NNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVR 240
Query: 241 VPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHD 300
VPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHD
Sbjct: 241 VPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHD 300
Query: 301 IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDSPDFSKITGKPIKLTQVEHRA 360
IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDSPDFSKITGKPIKLTQVEHRA
Sbjct: 301 IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDSPDFSKITGKPIKLTQVEHRA 360
Query: 361 GFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDPRGP 418
GFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDPRGP
Sbjct: 361 GFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDPRGP 418
>gi|115583663 alpha-2-plasmin inhibitor [Homo sapiens]
Length = 491
Score = 173 bits (439), Expect = 2e-43
Identities = 110/367 (29%), Positives = 190/367 (51%), Gaps = 13/367 (3%)
Query: 52 NKLAAAVSNFGYDLYRVRSSTSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYD 111
++LA A+ F DL+ + + TS N++LSPLSVA ALS L+LGA+ T + + L+
Sbjct: 80 HRLARAMMAFTADLFSLVAQTSTCPNLILSPLSVALALSHLALGAQNHTLQRLQQVLHAG 139
Query: 112 LISSPDIHGTYKELLDTVTAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLTG 171
S P + L + L A+R+ +K IK F+ E+ +G +P LTG
Sbjct: 140 --SGPCLPHLLSRLCQDLGPGAFRL--AARMYLQKGFPIKEDFLEQSEQLFGAKPVSLTG 195
Query: 172 NPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDF 231
DL IN WV+ +GK+ +P++ +LLL HF+G W KFD T + F
Sbjct: 196 KQEDDLANINQWVKEATEGKIQEFLSGLPEDTVLLLLNAIHFQGFWRNKFDPSLTQRDSF 255
Query: 232 YLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEE 291
+LDE+ TV V MM LR+ L ++A P +MS + +P N++ +
Sbjct: 256 HLDEQFTVPVEMMQARTYPLRWFLLEQPEIQVAHFPFKNNMSFVVLVPTHFEWNVSQVLA 315
Query: 292 SLTSEFIHD---IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDSPDFSKITG 348
+L+ + +H +R K + +PKL L ++ ++ +L ++ LQ LF +PD I+
Sbjct: 316 NLSWDTLHPPLVWERPTK-----VRLPKLYLKHQMDLVATLSQLGLQELFQAPDLRGISE 370
Query: 349 KPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLF 408
+ + ++ V+H++ E +E G + + + ++ + +N+PF+F + + TG LF
Sbjct: 371 QSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLS-SFSVNRPFLFFIFEDTTGLPLF 429
Query: 409 IGKILDP 415
+G + +P
Sbjct: 430 VGSVRNP 436
>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 157 bits (396), Expect = 2e-38
Identities = 117/417 (28%), Positives = 208/417 (49%), Gaps = 26/417 (6%)
Query: 13 LLGHSSCQNPASPPEEGSPDP-DSTGALVEEED-PFFKVPVNKLAAAVSNFGYDLYRVRS 70
LL C P S E+ D T ++D P F NK+ ++ F + LYR +
Sbjct: 11 LLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTF----NKITPNLAEFAFSLYRQLA 66
Query: 71 STSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPD--IHGTYKELLDT 128
S +TN+ SP+S+ATA + LSLG + T I L ++L P+ IH ++ELL T
Sbjct: 67 HQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRT 126
Query: 129 VTAP--QKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLT-GNPRLDLQEINNWVQ 185
+ P Q L + + + + L++ F+ ++K Y + + G+ ++IN++V+
Sbjct: 127 LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186
Query: 186 AQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMS 245
+GK+ KE+ + L+ FKG+W F+ + T EDF++D+ TV+VPMM
Sbjct: 187 KGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMK 246
Query: 246 DPKAVLRYGLDSDLSCK-----IAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHD 300
R G+ + CK + + G+ + IFFLP + L +E LT + I
Sbjct: 247 ------RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQHLENELTHDIITK 298
Query: 301 IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLF-DSPDFSKITGK-PIKLTQVEH 358
A L +PKL ++ ++ L ++ + +F + D S +T + P+KL++ H
Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358
Query: 359 RAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDP 415
+A +E G + L+ ++ P + N+PF+F++ + +T + LF+GK+++P
Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 157 bits (396), Expect = 2e-38
Identities = 117/417 (28%), Positives = 208/417 (49%), Gaps = 26/417 (6%)
Query: 13 LLGHSSCQNPASPPEEGSPDP-DSTGALVEEED-PFFKVPVNKLAAAVSNFGYDLYRVRS 70
LL C P S E+ D T ++D P F NK+ ++ F + LYR +
Sbjct: 11 LLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTF----NKITPNLAEFAFSLYRQLA 66
Query: 71 STSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPD--IHGTYKELLDT 128
S +TN+ SP+S+ATA + LSLG + T I L ++L P+ IH ++ELL T
Sbjct: 67 HQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRT 126
Query: 129 VTAP--QKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLT-GNPRLDLQEINNWVQ 185
+ P Q L + + + + L++ F+ ++K Y + + G+ ++IN++V+
Sbjct: 127 LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186
Query: 186 AQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMS 245
+GK+ KE+ + L+ FKG+W F+ + T EDF++D+ TV+VPMM
Sbjct: 187 KGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMK 246
Query: 246 DPKAVLRYGLDSDLSCK-----IAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHD 300
R G+ + CK + + G+ + IFFLP + L +E LT + I
Sbjct: 247 ------RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQHLENELTHDIITK 298
Query: 301 IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLF-DSPDFSKITGK-PIKLTQVEH 358
A L +PKL ++ ++ L ++ + +F + D S +T + P+KL++ H
Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358
Query: 359 RAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDP 415
+A +E G + L+ ++ P + N+PF+F++ + +T + LF+GK+++P
Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 157 bits (396), Expect = 2e-38
Identities = 117/417 (28%), Positives = 208/417 (49%), Gaps = 26/417 (6%)
Query: 13 LLGHSSCQNPASPPEEGSPDP-DSTGALVEEED-PFFKVPVNKLAAAVSNFGYDLYRVRS 70
LL C P S E+ D T ++D P F NK+ ++ F + LYR +
Sbjct: 11 LLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTF----NKITPNLAEFAFSLYRQLA 66
Query: 71 STSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPD--IHGTYKELLDT 128
S +TN+ SP+S+ATA + LSLG + T I L ++L P+ IH ++ELL T
Sbjct: 67 HQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRT 126
Query: 129 VTAP--QKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLT-GNPRLDLQEINNWVQ 185
+ P Q L + + + + L++ F+ ++K Y + + G+ ++IN++V+
Sbjct: 127 LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186
Query: 186 AQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMS 245
+GK+ KE+ + L+ FKG+W F+ + T EDF++D+ TV+VPMM
Sbjct: 187 KGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMK 246
Query: 246 DPKAVLRYGLDSDLSCK-----IAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHD 300
R G+ + CK + + G+ + IFFLP + L +E LT + I
Sbjct: 247 ------RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQHLENELTHDIITK 298
Query: 301 IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLF-DSPDFSKITGK-PIKLTQVEH 358
A L +PKL ++ ++ L ++ + +F + D S +T + P+KL++ H
Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358
Query: 359 RAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDP 415
+A +E G + L+ ++ P + N+PF+F++ + +T + LF+GK+++P
Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 157 bits (396), Expect = 2e-38
Identities = 117/417 (28%), Positives = 208/417 (49%), Gaps = 26/417 (6%)
Query: 13 LLGHSSCQNPASPPEEGSPDP-DSTGALVEEED-PFFKVPVNKLAAAVSNFGYDLYRVRS 70
LL C P S E+ D T ++D P F NK+ ++ F + LYR +
Sbjct: 11 LLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTF----NKITPNLAEFAFSLYRQLA 66
Query: 71 STSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPD--IHGTYKELLDT 128
S +TN+ SP+S+ATA + LSLG + T I L ++L P+ IH ++ELL T
Sbjct: 67 HQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRT 126
Query: 129 VTAP--QKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLT-GNPRLDLQEINNWVQ 185
+ P Q L + + + + L++ F+ ++K Y + + G+ ++IN++V+
Sbjct: 127 LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186
Query: 186 AQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMS 245
+GK+ KE+ + L+ FKG+W F+ + T EDF++D+ TV+VPMM
Sbjct: 187 KGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMK 246
Query: 246 DPKAVLRYGLDSDLSCK-----IAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHD 300
R G+ + CK + + G+ + IFFLP + L +E LT + I
Sbjct: 247 ------RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQHLENELTHDIITK 298
Query: 301 IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLF-DSPDFSKITGK-PIKLTQVEH 358
A L +PKL ++ ++ L ++ + +F + D S +T + P+KL++ H
Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358
Query: 359 RAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDP 415
+A +E G + L+ ++ P + N+PF+F++ + +T + LF+GK+++P
Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163534 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 157 bits (396), Expect = 2e-38
Identities = 117/417 (28%), Positives = 208/417 (49%), Gaps = 26/417 (6%)
Query: 13 LLGHSSCQNPASPPEEGSPDP-DSTGALVEEED-PFFKVPVNKLAAAVSNFGYDLYRVRS 70
LL C P S E+ D T ++D P F NK+ ++ F + LYR +
Sbjct: 11 LLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTF----NKITPNLAEFAFSLYRQLA 66
Query: 71 STSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPD--IHGTYKELLDT 128
S +TN+ SP+S+ATA + LSLG + T I L ++L P+ IH ++ELL T
Sbjct: 67 HQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRT 126
Query: 129 VTAP--QKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLT-GNPRLDLQEINNWVQ 185
+ P Q L + + + + L++ F+ ++K Y + + G+ ++IN++V+
Sbjct: 127 LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186
Query: 186 AQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMS 245
+GK+ KE+ + L+ FKG+W F+ + T EDF++D+ TV+VPMM
Sbjct: 187 KGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMK 246
Query: 246 DPKAVLRYGLDSDLSCK-----IAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHD 300
R G+ + CK + + G+ + IFFLP + L +E LT + I
Sbjct: 247 ------RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQHLENELTHDIITK 298
Query: 301 IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLF-DSPDFSKITGK-PIKLTQVEH 358
A L +PKL ++ ++ L ++ + +F + D S +T + P+KL++ H
Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358
Query: 359 RAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDP 415
+A +E G + L+ ++ P + N+PF+F++ + +T + LF+GK+++P
Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163532 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 157 bits (396), Expect = 2e-38
Identities = 117/417 (28%), Positives = 208/417 (49%), Gaps = 26/417 (6%)
Query: 13 LLGHSSCQNPASPPEEGSPDP-DSTGALVEEED-PFFKVPVNKLAAAVSNFGYDLYRVRS 70
LL C P S E+ D T ++D P F NK+ ++ F + LYR +
Sbjct: 11 LLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTF----NKITPNLAEFAFSLYRQLA 66
Query: 71 STSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPD--IHGTYKELLDT 128
S +TN+ SP+S+ATA + LSLG + T I L ++L P+ IH ++ELL T
Sbjct: 67 HQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRT 126
Query: 129 VTAP--QKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLT-GNPRLDLQEINNWVQ 185
+ P Q L + + + + L++ F+ ++K Y + + G+ ++IN++V+
Sbjct: 127 LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186
Query: 186 AQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMS 245
+GK+ KE+ + L+ FKG+W F+ + T EDF++D+ TV+VPMM
Sbjct: 187 KGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMK 246
Query: 246 DPKAVLRYGLDSDLSCK-----IAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHD 300
R G+ + CK + + G+ + IFFLP + L +E LT + I
Sbjct: 247 ------RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQHLENELTHDIITK 298
Query: 301 IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLF-DSPDFSKITGK-PIKLTQVEH 358
A L +PKL ++ ++ L ++ + +F + D S +T + P+KL++ H
Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358
Query: 359 RAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDP 415
+A +E G + L+ ++ P + N+PF+F++ + +T + LF+GK+++P
Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163530 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 157 bits (396), Expect = 2e-38
Identities = 117/417 (28%), Positives = 208/417 (49%), Gaps = 26/417 (6%)
Query: 13 LLGHSSCQNPASPPEEGSPDP-DSTGALVEEED-PFFKVPVNKLAAAVSNFGYDLYRVRS 70
LL C P S E+ D T ++D P F NK+ ++ F + LYR +
Sbjct: 11 LLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTF----NKITPNLAEFAFSLYRQLA 66
Query: 71 STSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPD--IHGTYKELLDT 128
S +TN+ SP+S+ATA + LSLG + T I L ++L P+ IH ++ELL T
Sbjct: 67 HQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRT 126
Query: 129 VTAP--QKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLT-GNPRLDLQEINNWVQ 185
+ P Q L + + + + L++ F+ ++K Y + + G+ ++IN++V+
Sbjct: 127 LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186
Query: 186 AQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMS 245
+GK+ KE+ + L+ FKG+W F+ + T EDF++D+ TV+VPMM
Sbjct: 187 KGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMK 246
Query: 246 DPKAVLRYGLDSDLSCK-----IAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHD 300
R G+ + CK + + G+ + IFFLP + L +E LT + I
Sbjct: 247 ------RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQHLENELTHDIITK 298
Query: 301 IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLF-DSPDFSKITGK-PIKLTQVEH 358
A L +PKL ++ ++ L ++ + +F + D S +T + P+KL++ H
Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358
Query: 359 RAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDP 415
+A +E G + L+ ++ P + N+PF+F++ + +T + LF+GK+++P
Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163528 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 157 bits (396), Expect = 2e-38
Identities = 117/417 (28%), Positives = 208/417 (49%), Gaps = 26/417 (6%)
Query: 13 LLGHSSCQNPASPPEEGSPDP-DSTGALVEEED-PFFKVPVNKLAAAVSNFGYDLYRVRS 70
LL C P S E+ D T ++D P F NK+ ++ F + LYR +
Sbjct: 11 LLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTF----NKITPNLAEFAFSLYRQLA 66
Query: 71 STSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPD--IHGTYKELLDT 128
S +TN+ SP+S+ATA + LSLG + T I L ++L P+ IH ++ELL T
Sbjct: 67 HQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRT 126
Query: 129 VTAP--QKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLT-GNPRLDLQEINNWVQ 185
+ P Q L + + + + L++ F+ ++K Y + + G+ ++IN++V+
Sbjct: 127 LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186
Query: 186 AQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMS 245
+GK+ KE+ + L+ FKG+W F+ + T EDF++D+ TV+VPMM
Sbjct: 187 KGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMK 246
Query: 246 DPKAVLRYGLDSDLSCK-----IAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHD 300
R G+ + CK + + G+ + IFFLP + L +E LT + I
Sbjct: 247 ------RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQHLENELTHDIITK 298
Query: 301 IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLF-DSPDFSKITGK-PIKLTQVEH 358
A L +PKL ++ ++ L ++ + +F + D S +T + P+KL++ H
Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358
Query: 359 RAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDP 415
+A +E G + L+ ++ P + N+PF+F++ + +T + LF+GK+++P
Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 157 bits (396), Expect = 2e-38
Identities = 117/417 (28%), Positives = 208/417 (49%), Gaps = 26/417 (6%)
Query: 13 LLGHSSCQNPASPPEEGSPDP-DSTGALVEEED-PFFKVPVNKLAAAVSNFGYDLYRVRS 70
LL C P S E+ D T ++D P F NK+ ++ F + LYR +
Sbjct: 11 LLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTF----NKITPNLAEFAFSLYRQLA 66
Query: 71 STSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPD--IHGTYKELLDT 128
S +TN+ SP+S+ATA + LSLG + T I L ++L P+ IH ++ELL T
Sbjct: 67 HQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRT 126
Query: 129 VTAP--QKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLT-GNPRLDLQEINNWVQ 185
+ P Q L + + + + L++ F+ ++K Y + + G+ ++IN++V+
Sbjct: 127 LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186
Query: 186 AQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMS 245
+GK+ KE+ + L+ FKG+W F+ + T EDF++D+ TV+VPMM
Sbjct: 187 KGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMK 246
Query: 246 DPKAVLRYGLDSDLSCK-----IAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHD 300
R G+ + CK + + G+ + IFFLP + L +E LT + I
Sbjct: 247 ------RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQHLENELTHDIITK 298
Query: 301 IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLF-DSPDFSKITGK-PIKLTQVEH 358
A L +PKL ++ ++ L ++ + +F + D S +T + P+KL++ H
Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358
Query: 359 RAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDP 415
+A +E G + L+ ++ P + N+PF+F++ + +T + LF+GK+++P
Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 157 bits (396), Expect = 2e-38
Identities = 117/417 (28%), Positives = 208/417 (49%), Gaps = 26/417 (6%)
Query: 13 LLGHSSCQNPASPPEEGSPDP-DSTGALVEEED-PFFKVPVNKLAAAVSNFGYDLYRVRS 70
LL C P S E+ D T ++D P F NK+ ++ F + LYR +
Sbjct: 11 LLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTF----NKITPNLAEFAFSLYRQLA 66
Query: 71 STSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPD--IHGTYKELLDT 128
S +TN+ SP+S+ATA + LSLG + T I L ++L P+ IH ++ELL T
Sbjct: 67 HQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRT 126
Query: 129 VTAP--QKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLT-GNPRLDLQEINNWVQ 185
+ P Q L + + + + L++ F+ ++K Y + + G+ ++IN++V+
Sbjct: 127 LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186
Query: 186 AQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMS 245
+GK+ KE+ + L+ FKG+W F+ + T EDF++D+ TV+VPMM
Sbjct: 187 KGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMK 246
Query: 246 DPKAVLRYGLDSDLSCK-----IAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHD 300
R G+ + CK + + G+ + IFFLP + L +E LT + I
Sbjct: 247 ------RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQHLENELTHDIITK 298
Query: 301 IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLF-DSPDFSKITGK-PIKLTQVEH 358
A L +PKL ++ ++ L ++ + +F + D S +T + P+KL++ H
Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358
Query: 359 RAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDP 415
+A +E G + L+ ++ P + N+PF+F++ + +T + LF+GK+++P
Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 157 bits (396), Expect = 2e-38
Identities = 117/417 (28%), Positives = 208/417 (49%), Gaps = 26/417 (6%)
Query: 13 LLGHSSCQNPASPPEEGSPDP-DSTGALVEEED-PFFKVPVNKLAAAVSNFGYDLYRVRS 70
LL C P S E+ D T ++D P F NK+ ++ F + LYR +
Sbjct: 11 LLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTF----NKITPNLAEFAFSLYRQLA 66
Query: 71 STSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPD--IHGTYKELLDT 128
S +TN+ SP+S+ATA + LSLG + T I L ++L P+ IH ++ELL T
Sbjct: 67 HQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRT 126
Query: 129 VTAP--QKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLT-GNPRLDLQEINNWVQ 185
+ P Q L + + + + L++ F+ ++K Y + + G+ ++IN++V+
Sbjct: 127 LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186
Query: 186 AQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMS 245
+GK+ KE+ + L+ FKG+W F+ + T EDF++D+ TV+VPMM
Sbjct: 187 KGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMK 246
Query: 246 DPKAVLRYGLDSDLSCK-----IAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHD 300
R G+ + CK + + G+ + IFFLP + L +E LT + I
Sbjct: 247 ------RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQHLENELTHDIITK 298
Query: 301 IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLF-DSPDFSKITGK-PIKLTQVEH 358
A L +PKL ++ ++ L ++ + +F + D S +T + P+KL++ H
Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358
Query: 359 RAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDP 415
+A +E G + L+ ++ P + N+PF+F++ + +T + LF+GK+++P
Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|73858564 corticosteroid binding globulin precursor [Homo
sapiens]
Length = 405
Score = 148 bits (374), Expect = 8e-36
Identities = 103/369 (27%), Positives = 190/369 (51%), Gaps = 10/369 (2%)
Query: 54 LAAAVSNFGYDLYRVRSSTSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLI 113
LA+A +F + LY+ + SP N+ +SP+S++ AL+ LSLG T + + + L ++L
Sbjct: 39 LASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLT 98
Query: 114 --SSPDIHGTYKELLDTVTAPQKNLKSA--SRIVFEKKLRIKSSFVAPLEKSYGTRPRVL 169
S +IH ++ L +L+ + + + L + SF A ++ Y + +
Sbjct: 99 ERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAM 158
Query: 170 TGNPRLDL-QEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSL 228
++IN++V+ + +GK+ + ++L+ FKG W FD T
Sbjct: 159 NFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTRE 218
Query: 229 EDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTL 288
E+FY+DE V+VPMM + + Y D++L C++ Q+ G+ ++ F LP K N +
Sbjct: 219 ENFYVDETTVVKVPMMLQ-SSTISYLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTVI 277
Query: 289 IEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLF-DSPDFSKIT 347
+L+ + I+ L + Q L +PK+ +S ++ L+EM + LF + +FS+IT
Sbjct: 278 --AALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRIT 335
Query: 348 -GKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGAL 406
+K ++V H+A + NE+G T S G+ + P+ NQPFI ++ D T +
Sbjct: 336 QDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWSS 395
Query: 407 LFIGKILDP 415
LF+ ++++P
Sbjct: 396 LFLARVMNP 404
>gi|73858570 serpin peptidase inhibitor, clade G, member 1 precursor
[Homo sapiens]
Length = 500
Score = 147 bits (371), Expect = 2e-35
Identities = 97/368 (26%), Positives = 181/368 (49%), Gaps = 15/368 (4%)
Query: 54 LAAAVSNFGYDLYRVRSSTSPT-TNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDL 112
L A+ +F LY S+ TN+ SP S+A+ L+ + LGA + T++ + L Y
Sbjct: 142 LGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYP- 200
Query: 113 ISSPDIHGTYKELLDTVTAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLTGN 172
D ++ L T K + S S+I L I+ +FV Y + PRVL+ N
Sbjct: 201 ---KDFTCVHQALKGFTT---KGVTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNN 254
Query: 173 PRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFY 232
+L+ IN WV K++R +P + ++LL + +W T FD +KT +E F+
Sbjct: 255 SDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFH 314
Query: 233 LDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEES 292
+ ++VPMM+ K + + +D L K+ QL L+ ++S++ +P + L +E++
Sbjct: 315 F-KNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQA 373
Query: 293 LTSEFIHDIDREL---KTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDSPDFSKITGK 349
L+ I +L K +LT+P++K++ ++ +++++ + +T
Sbjct: 374 LSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYDLNLCGLTED 433
Query: 350 P-IKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLF 408
P ++++ ++H+ E E G + + A L + + QPF+FVL D +F
Sbjct: 434 PDLQVSAMQHQTVLELTETGVEAAAASAISVARTL--LVFEVQQPFLFVLWDQQHKFPVF 491
Query: 409 IGKILDPR 416
+G++ DPR
Sbjct: 492 MGRVYDPR 499
>gi|73858568 serpin peptidase inhibitor, clade G, member 1 precursor
[Homo sapiens]
Length = 500
Score = 147 bits (371), Expect = 2e-35
Identities = 97/368 (26%), Positives = 181/368 (49%), Gaps = 15/368 (4%)
Query: 54 LAAAVSNFGYDLYRVRSSTSPT-TNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDL 112
L A+ +F LY S+ TN+ SP S+A+ L+ + LGA + T++ + L Y
Sbjct: 142 LGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYP- 200
Query: 113 ISSPDIHGTYKELLDTVTAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLTGN 172
D ++ L T K + S S+I L I+ +FV Y + PRVL+ N
Sbjct: 201 ---KDFTCVHQALKGFTT---KGVTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNN 254
Query: 173 PRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFY 232
+L+ IN WV K++R +P + ++LL + +W T FD +KT +E F+
Sbjct: 255 SDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFH 314
Query: 233 LDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEES 292
+ ++VPMM+ K + + +D L K+ QL L+ ++S++ +P + L +E++
Sbjct: 315 F-KNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQA 373
Query: 293 LTSEFIHDIDREL---KTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDSPDFSKITGK 349
L+ I +L K +LT+P++K++ ++ +++++ + +T
Sbjct: 374 LSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYDLNLCGLTED 433
Query: 350 P-IKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLF 408
P ++++ ++H+ E E G + + A L + + QPF+FVL D +F
Sbjct: 434 PDLQVSAMQHQTVLELTETGVEAAAASAISVARTL--LVFEVQQPFLFVLWDQQHKFPVF 491
Query: 409 IGKILDPR 416
+G++ DPR
Sbjct: 492 MGRVYDPR 499
>gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor
[Homo sapiens]
Length = 423
Score = 145 bits (366), Expect = 7e-35
Identities = 117/428 (27%), Positives = 214/428 (50%), Gaps = 19/428 (4%)
Query: 1 MQALVLLLCIGALLGHSSCQNPASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSN 60
M+ ++ LL +G LL C PA SP D E +D V + LA+A +
Sbjct: 1 MERMLPLLALG-LLAAGFC--PAVLCHPNSP-LDEENLTQENQDRGTHVDLG-LASANVD 55
Query: 61 FGYDLYRVRSSTSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLI--SSPDI 118
F + LY+ +P NV+ SPLS++TAL+ LSLGA T + I + L ++L S +I
Sbjct: 56 FAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEI 115
Query: 119 HGTYKELLDTV--TAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLTGNPRLD 176
H +++ LL T+ ++ + L + + +++L + F ++ YG+
Sbjct: 116 HQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAA 175
Query: 177 LQE-INNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDE 235
++ IN++V+ +GK+ K++ + ++L+ FK +W FD + T FYL +
Sbjct: 176 AKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSK 235
Query: 236 ERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTS 295
++ V VPMMS + Y D +LSC + +L TG+ S +F LP + + +E L
Sbjct: 236 KKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQ--DKMEEVEAMLLP 293
Query: 296 EFIHDIDRELKTVQ-AVLTVPKLKLSYEGEVTKSLQEMKLQSLFDS-PDFSKITG-KPIK 352
E + L+ + L +PK +S + + L ++ ++ F S D S ITG + +
Sbjct: 294 ETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLA 353
Query: 353 LTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLD----YHLNQPFIFVLRDTDTGALLF 408
++QV H+A + E+G + + ++ L+ ++ N+PF+ ++ TDT + F
Sbjct: 354 VSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFF 413
Query: 409 IGKILDPR 416
+ K+ +P+
Sbjct: 414 MSKVTNPK 421
>gi|122937297 serpin peptidase inhibitor, clade A (alpha-1
antiproteinase, antitrypsin), member 11 [Homo sapiens]
Length = 422
Score = 142 bits (358), Expect = 6e-34
Identities = 109/421 (25%), Positives = 209/421 (49%), Gaps = 32/421 (7%)
Query: 13 LLGHSSCQNPASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSNFGYDLYRVRSST 72
+L CQ + ++ P + E P + +++ ++NF LY+ ++
Sbjct: 13 ILASVHCQPLLAHGDKSLQGPQPPRHQLSEPAPAY----HRITPTITNFALRLYKELAAD 68
Query: 73 SPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSP--DIHGTYKELLDTVT 130
+P N+ SP+S++T L+ LSLGA+ T ++I L ++L +P DIH ++ LL T+
Sbjct: 69 APG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFRSLLHTLA 127
Query: 131 --APQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGT-------RPRVLTGNPRLDLQEIN 181
+P+ LK + + +K+L+ + ++ +++ YG V TG ++IN
Sbjct: 128 LPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTG------RQIN 181
Query: 182 NWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSL-EDFYLDEERTVR 240
++++ Q G++ E + ++L FK +W F +T E F++DE +++
Sbjct: 182 DYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQ 241
Query: 241 VPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHD 300
VPMM K + R+ D DL+C + Q+ G+ + LP + +E +L + +
Sbjct: 242 VPMMHQ-KEMHRFLYDQDLACTVLQIEYRGNALALLVLP--DPGKMKQVEAALQPQTLRK 298
Query: 301 IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFD-SPDFSKITGKPIK-LTQVEH 358
+ L L +P+ +S + L ++ L ++ + DFS +TG+ K +++V H
Sbjct: 299 WGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSH 358
Query: 359 RAGFEWNEDGAGTTPSPGL--QPAHLTFPLD--YHLNQPFIFVLRDTDTGALLFIGKILD 414
+A + +E G + GL QP L D H N+PF+ +L + T +LLF+GK+++
Sbjct: 359 KAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVN 418
Query: 415 P 415
P
Sbjct: 419 P 419
>gi|110225347 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 9 isoform
A [Homo sapiens]
Length = 435
Score = 139 bits (350), Expect = 5e-33
Identities = 105/413 (25%), Positives = 210/413 (50%), Gaps = 34/413 (8%)
Query: 19 CQNPASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSNFGYDLYRVRSSTSPTTNV 78
C +PA+ P P P ST + P +++ + ++F + LYR +P+ N+
Sbjct: 38 CVSPANAPS-AYPRPSSTKS----------TPASQVYSLNTDFAFRLYRRLVLETPSQNI 86
Query: 79 LLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPD--IHGTYKELLDTVTAPQKN- 135
SP+SV+T+L+ LSLGA T++ I + L ++L +P+ IH ++ L+ ++T P K+
Sbjct: 87 FFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQHLVHSLTVPSKDL 146
Query: 136 -LKSASRIVFEKKLRIKSSFVAPLEKSYGTRP-RVLTGNPRLDLQEINNWVQAQMKGKLA 193
LK S + +K+L+++++F+ +++ Y NP + IN+ V+ + +GK+
Sbjct: 147 TLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARINSHVKKKTQGKVV 206
Query: 194 RSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLE-DFYLDEERTVRVPMMSDPKAVLR 252
+ + +++L+ FK +W F T F + E+ TV VPMM K
Sbjct: 207 DIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQ-KEQFA 265
Query: 253 YGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVL 312
+G+D++L+C + Q+ G F LP K + +E++L++ + L+ +
Sbjct: 266 FGVDTELNCFVLQMDYKGDAVAFFVLPSK--GKMRQLEQALSARTLRKWSHSLQKRWIEV 323
Query: 313 TVPKLKLSYEGEVTKSLQEMKLQSLFD-SPDFSKITGK-PIKLTQVEHRAGFEWNEDGAG 370
+P+ +S + L +M +Q++FD + DFS I + +++++ H+A + +E+G
Sbjct: 324 FIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVSEEGTE 383
Query: 371 TTPSPGLQ--------PAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDP 415
T + + P++ T N+ F+ ++ + T +LF+GK+ +P
Sbjct: 384 ATAATTTKFIVRSKDGPSYFT----VSFNRTFLMMITNKATDGILFLGKVENP 432
>gi|21361302 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 4 [Homo
sapiens]
Length = 427
Score = 138 bits (348), Expect = 8e-33
Identities = 105/383 (27%), Positives = 186/383 (48%), Gaps = 16/383 (4%)
Query: 50 PVNKLAAAVSNFGYDLYRVRSSTSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALY 109
P K+A A ++F + Y + +S +P N+ SPLS++ A + LSLGA + S I L
Sbjct: 47 PSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLG 106
Query: 110 YDL--ISSPDIHGTYKELLDTVTAPQKNLKS--ASRIVFEKKLRIKSSFVAPLEKSYGTR 165
++L +S D+H ++ LL T+ P L++ S + L+ + F+ Y +
Sbjct: 107 FNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAK 166
Query: 166 PRVLTGNPRLD-LQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSR 224
+ +Q IN+ V+ + +GK+ E+ ++ ++L+ +FK W F S
Sbjct: 167 LFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISS 226
Query: 225 KTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQ 284
+T+ +DFY+DE TVRVPMM + Y D L C + ++ G ++ F LP +
Sbjct: 227 RTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQ--G 284
Query: 285 NLTLIEESLTSEFIHDIDRELKT----VQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDS 340
+ IEE LT E + + L+ + L +PK +S + + L + LF
Sbjct: 285 KMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSK 344
Query: 341 -PDFSKIT-GKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHL---NQPFI 395
D S IT + ++ ++ H+A + +E G + + + H+ N+PF+
Sbjct: 345 WADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFL 404
Query: 396 FVLRDTDTGALLFIGKILDPRGP 418
V+ T T ++LF+GK++DP P
Sbjct: 405 VVIFSTSTQSVLFLGKVVDPTKP 427
>gi|154759291 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 10 [Homo
sapiens]
Length = 444
Score = 137 bits (346), Expect = 1e-32
Identities = 103/401 (25%), Positives = 200/401 (49%), Gaps = 12/401 (2%)
Query: 24 SPPEEGSPDPDSTGALV-EEEDPFFKVPVNKLAAAVSNFGYDLYRVRSSTSPTTNVLLSP 82
+P EE + +++ EEE + +LA SNFG+ L R + S N++ SP
Sbjct: 44 APKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLR-KISMRHDGNMVFSP 102
Query: 83 LSVATALSALSLGAEQRTESIIHRALYYDLISSPD---IHGTYKELLDTVTAP-QKNLKS 138
++ A++ L LGA TE+ I R L+ + + +K L +T++ + L
Sbjct: 103 FGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQ 162
Query: 139 ASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLT-GNPRLDLQEINNWVQAQMKGKLARSTK 197
S K +K +F ++ + T + N + +N+++ + +GK+ +
Sbjct: 163 GSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFD 222
Query: 198 EIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDS 257
EI E ++L+ FKG+W+T FD T ++ F+LD+ +T++VPMM D
Sbjct: 223 EINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYG-AGKFASTFDK 281
Query: 258 DLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKL 317
+ C + +LP G+ +++ L K+ +L L E+ LT++ + R +KT + PK
Sbjct: 282 NFRCHVLKLPYQGNATMLVVLMEKMGDHLAL-EDYLTTDLVETWLRNMKTRNMEVFFPKF 340
Query: 318 KLSYEGEVTKSLQEMKLQSLFDS-PDFSKI--TGKPIKLTQVEHRAGFEWNEDGAGTTPS 374
KL + E+ + L++M ++ +F D S++ TG+ +++++V R E +E G
Sbjct: 341 KLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAG 400
Query: 375 PGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDP 415
+ + P +++PF F++ + +G LLF+G++++P
Sbjct: 401 ILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNP 441
>gi|7705879 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 10 [Homo
sapiens]
Length = 444
Score = 137 bits (346), Expect = 1e-32
Identities = 103/401 (25%), Positives = 200/401 (49%), Gaps = 12/401 (2%)
Query: 24 SPPEEGSPDPDSTGALV-EEEDPFFKVPVNKLAAAVSNFGYDLYRVRSSTSPTTNVLLSP 82
+P EE + +++ EEE + +LA SNFG+ L R + S N++ SP
Sbjct: 44 APKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLR-KISMRHDGNMVFSP 102
Query: 83 LSVATALSALSLGAEQRTESIIHRALYYDLISSPD---IHGTYKELLDTVTAP-QKNLKS 138
++ A++ L LGA TE+ I R L+ + + +K L +T++ + L
Sbjct: 103 FGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQ 162
Query: 139 ASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLT-GNPRLDLQEINNWVQAQMKGKLARSTK 197
S K +K +F ++ + T + N + +N+++ + +GK+ +
Sbjct: 163 GSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFD 222
Query: 198 EIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDS 257
EI E ++L+ FKG+W+T FD T ++ F+LD+ +T++VPMM D
Sbjct: 223 EINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYG-AGKFASTFDK 281
Query: 258 DLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKL 317
+ C + +LP G+ +++ L K+ +L L E+ LT++ + R +KT + PK
Sbjct: 282 NFRCHVLKLPYQGNATMLVVLMEKMGDHLAL-EDYLTTDLVETWLRNMKTRNMEVFFPKF 340
Query: 318 KLSYEGEVTKSLQEMKLQSLFDS-PDFSKI--TGKPIKLTQVEHRAGFEWNEDGAGTTPS 374
KL + E+ + L++M ++ +F D S++ TG+ +++++V R E +E G
Sbjct: 341 KLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAG 400
Query: 375 PGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDP 415
+ + P +++PF F++ + +G LLF+G++++P
Sbjct: 401 ILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNP 441
>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 1 [Homo sapiens]
Length = 379
Score = 137 bits (346), Expect = 1e-32
Identities = 96/382 (25%), Positives = 191/382 (50%), Gaps = 20/382 (5%)
Query: 51 VNKLAAAVSNFGYDLYRVRSSTSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYY 110
+ +L++A + F DL+ S +P N+ +SP S+++A++ + LG T + + + ++
Sbjct: 1 MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
Query: 111 DLISSPDIHGTYKELLDTVTAPQKN--LKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRV 168
+ + ++H ++ L + + LK A+R+ EK F+ +K+YG
Sbjct: 61 NTVE--EVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLAS 118
Query: 169 LTGNPRLD--LQEINNWVQAQMKGKLAR--STKEIPDEISILLLGVAHFKGQWVTKFDSR 224
+ + + IN WV+ Q +GK+ ++ + + ++L+ +FKG W KF
Sbjct: 119 VDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKE 178
Query: 225 KTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTG-SMSIIFFLPLKV- 282
T+ F L+++ V MM K YG DL C++ +LP G +S++ LP +
Sbjct: 179 ATTNAPFRLNKKDRKTVKMMYQKKK-FAYGYIEDLKCRVLELPYQGEELSMVILLPDDIE 237
Query: 283 --TQNLTLIEESLTSEFIHDIDR--ELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLF 338
+ L IEE LT E +H+ + L ++ +++P+ KL + L + +Q LF
Sbjct: 238 DESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLF 297
Query: 339 DS--PDFSKITG-KPIKLTQVEHRAGFEWNEDGA-GTTPSPGLQPAHLTFPLD-YHLNQP 393
+S D S ++G + I ++++ H++ E NE+G + G+ + P + + + P
Sbjct: 298 NSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHP 357
Query: 394 FIFVLRDTDTGALLFIGKILDP 415
F+F +R +G++LF+G+ P
Sbjct: 358 FLFFIRHNSSGSILFLGRFSSP 379
>gi|27777657 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 12 [Homo
sapiens]
Length = 414
Score = 137 bits (344), Expect = 2e-32
Identities = 97/391 (24%), Positives = 195/391 (49%), Gaps = 10/391 (2%)
Query: 33 PDSTGALVEEEDPFFKVPVNKLAAAVSNFGYDLYRVRSSTSPTTNVLLSPLSVATALSAL 92
P + AL E + ++ +LA + G+ L + + +P N+ LSPLS++TA S L
Sbjct: 27 PRNYKALSEVQGWKQRMAAKELARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSML 86
Query: 93 SLGAEQRTESIIHRALYYDLISSPDIHGTYKELLDTVTAPQKNLKSA--SRIVFEKKLRI 150
LGA+ T I + + + D+H + ++ +T ++LK + + + +++L+
Sbjct: 87 CLGAQDSTLDEIKQGFNFRKMPEKDLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQP 146
Query: 151 KSSFVAPLEKSYGTRPRVLTGNPRLDL--QEINNWVQAQMKGKLARSTKEIPDEISILLL 208
+ F+ + Y +LT L++ ++IN+++ + GK+ + I +LL
Sbjct: 147 QRKFLEDAKNFYSAE-TILTNFQNLEMAQKQINDFISQKTHGKINNLIENIDPGTVMLLA 205
Query: 209 GVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPL 268
F+ +W +FD T EDF+L++ +V+VPMM + + G D LSC I ++P
Sbjct: 206 NYIFFRARWKHEFDPNVTKEEDFFLEKNSSVKVPMMF-RSGIYQVGYDDKLSCTILEIPY 264
Query: 269 TGSMSIIFFLPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKS 328
+++ IF LP + L +E+ L + L ++VP+L ++ ++ K+
Sbjct: 265 QKNITAIFILPDE--GKLKHLEKGLQVDTFSRWKTLLSRRVVDVSVPRLHMTGTFDLKKT 322
Query: 329 LQEMKLQSLFDS-PDFSKIT-GKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPL 386
L + + +F+ D +KI + +K+ + H+A + +E G G Q + PL
Sbjct: 323 LSYIGVSKIFEEHGDLTKIAPHRSLKVGEAVHKAELKMDERGTEGAAGTGAQTLPMETPL 382
Query: 387 DYHLNQPFIFVLRDTDTGALLFIGKILDPRG 417
+++P++ ++ ++LF+GKI++P G
Sbjct: 383 VVKIDKPYLLLIYSEKIPSVLFLGKIVNPIG 413
>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 5 [Homo
sapiens]
Length = 406
Score = 135 bits (339), Expect = 9e-32
Identities = 98/367 (26%), Positives = 187/367 (50%), Gaps = 18/367 (4%)
Query: 60 NFGYDLYRVRSSTSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDL--ISSPD 117
+F +DLYR +S +P+ ++ SP+S++ +L+ LSLGA T+ I L +L S +
Sbjct: 47 DFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKE 106
Query: 118 IHGTYKELLDTVTAPQKN--LKSASRIVFEKKLRIKSSFVAPLEKSY--GTRPRVLTGNP 173
+H +++LL + P+ L + + + + ++ +FV+ ++ Y T P +
Sbjct: 107 LHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSA 166
Query: 174 RLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYL 233
+++IN++V Q KGK+ K + ++++ FK +W T F+ + T +DFY+
Sbjct: 167 GA-MKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYV 225
Query: 234 DEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESL 293
E VRVPMMS + Y LD +LSC++ +P G+ + +F LP + + +E L
Sbjct: 226 TSETVVRVPMMS-REDQYHYLLDRNLSCRVVGVPYQGNATALFILPSE--GKMQQVENGL 282
Query: 294 TSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDS-PDFSKITG-KPI 351
+ + + + K Q L +PK + ++ K L + + ++F S D S I+ I
Sbjct: 283 SEKTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNI 342
Query: 352 KLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYH---LNQPFIFVLRDTDTGALLF 408
+++++ H+A E +E G + G + L+ N+PF+ + D + +LF
Sbjct: 343 QVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNN---ILF 399
Query: 409 IGKILDP 415
+GK+ P
Sbjct: 400 LGKVNRP 406
>gi|73858566 heparin cofactor II precursor [Homo sapiens]
Length = 499
Score = 133 bits (335), Expect = 3e-31
Identities = 94/381 (24%), Positives = 184/381 (48%), Gaps = 17/381 (4%)
Query: 48 KVPVNKLAAAVSNFGYDLYRV-RSSTSPTTNVLLSPLSVATALSALSLGAEQRTESIIHR 106
K + +L + F ++LYRV + + N+ ++P+ ++TA+ +SLG + T +H
Sbjct: 120 KSRIQRLNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHS 179
Query: 107 ALYY-DLISSPD------IHGTYKELLDTVTAPQ--KNLKSASRIVFEKKLRIKSSFVAP 157
L++ D +++ IH +++L + L+S + + +K+ I F
Sbjct: 180 ILHFKDFVNASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTK 239
Query: 158 LEKSYGTRPRVLTGNPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQW 217
+ + Y ++ + + + NN + KG + + + I +++L +FKG W
Sbjct: 240 VREYYFAEAQIADFSDPAFISKTNNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSW 299
Query: 218 VTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFF 277
V KF T +F L+E V+V MM K D +L C I QL G +S++
Sbjct: 300 VNKFPVEMTHNHNFRLNEREVVKVSMM-QTKGNFLAANDQELDCDILQLEYVGGISMLIV 358
Query: 278 LPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSL 337
+P K++ TL E LT + + + + +PK KL + +SL+ M ++ L
Sbjct: 359 VPHKMSGMKTL-EAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRML 417
Query: 338 FD-SPDFSKITGKPIKLTQVEHRAGFEWNEDG--AGTTPSPGLQPAHLTFPLDYHLNQPF 394
FD + + + I+ + I + +H+ NE+G A T + G P L+ + + +++PF
Sbjct: 418 FDKNGNMAGISDQRIAIDLFKHQGTITVNEEGTQATTVTTVGFMP--LSTQVRFTVDRPF 475
Query: 395 IFVLRDTDTGALLFIGKILDP 415
+F++ + T LLF+G++ +P
Sbjct: 476 LFLIYEHRTSCLLFMGRVANP 496
>gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,
member 7 [Homo sapiens]
Length = 415
Score = 132 bits (332), Expect = 6e-31
Identities = 98/375 (26%), Positives = 190/375 (50%), Gaps = 15/375 (4%)
Query: 53 KLAAAVSNFGYDLYRVRSSTSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDL 112
K+++ ++F ++LYR + +P N+ SP+S++ AL LS GA T++ I L ++L
Sbjct: 41 KMSSINADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNL 100
Query: 113 ISSP--DIHGTYKELLDTVTAPQKNLKS--ASRIVFEKKLRIKSSFVAPLEKSYGTRPRV 168
+P +I ++ L+ ++ P+K L+ + + K L+ + F+ ++ Y T
Sbjct: 101 TDTPMVEIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFS 160
Query: 169 LT-GNPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKT- 226
N QEIN+ V+ Q KGK+ +++ ++L+ HFK QW FD KT
Sbjct: 161 TDFSNISAAKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTE 220
Query: 227 SLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNL 286
F +D+ TV+VPMM + +D +L+C + Q+ + + +F LP + +
Sbjct: 221 DSSSFLIDKTTTVQVPMMHQMEQYYHL-VDMELNCTVLQMDYSKNALALFVLPKE--GQM 277
Query: 287 TLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLF-DSPDFSK 345
+E +++S+ + +R L+ L VPK +S ++ +L +M +Q + ++ DFS
Sbjct: 278 ESVEAAMSSKTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSG 337
Query: 346 IT-GKPIKLTQVEHRAGFEWNEDGAGTTPSPGL----QPAHLTFPLDYHLNQPFIFVLRD 400
+T +KL+ H+A E G P + QP + +++ F+ ++ +
Sbjct: 338 LTEDNGLKLSNAAHKAVLHIGEKGTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILE 397
Query: 401 TDTGALLFIGKILDP 415
T ++LF+GK+++P
Sbjct: 398 RSTRSILFLGKVVNP 412
>gi|32454741 serine (or cysteine) proteinase inhibitor, clade H,
member 1 precursor [Homo sapiens]
Length = 418
Score = 128 bits (321), Expect = 1e-29
Identities = 101/375 (26%), Positives = 168/375 (44%), Gaps = 17/375 (4%)
Query: 54 LAAAVSNFGYDLYRVRSSTSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLI 113
LA + + LY+ + N+L+SP+ VA++L +SLG + T S L + +
Sbjct: 43 LAERSAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQL 102
Query: 114 SSPDIHGTYKELLDTV---TAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTR-PRVL 169
++H ELL ++ TA K SR+ + FV ++ Y ++
Sbjct: 103 RDEEVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKIN 162
Query: 170 TGNPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLE 229
+ R LQ IN W GKL TK++ LL+ FK W KF +
Sbjct: 163 FRDKRSALQSINEWAAQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNR 222
Query: 230 DFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLI 289
F + TV V MM + Y D +I ++PL +S + L + L +
Sbjct: 223 GFMVTRSYTVGV-MMMHRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERL 281
Query: 290 EESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDS--PDFSKIT 347
E+ LT E + +++ +++PK + ++ K L + L D D S+++
Sbjct: 282 EKLLTKEQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMS 341
Query: 348 GKP-IKLTQVEHRAGFEWNEDGAGTTPSPGLQPAH----LTFPLDYHLNQPFIFVLRDTD 402
GK + L V H FE + DG +P Q + L P ++ + PFIF++RDT
Sbjct: 342 GKKDLYLASVFHATAFELDTDG-----NPFDQDIYGREELRSPKLFYADHPFIFLVRDTQ 396
Query: 403 TGALLFIGKILDPRG 417
+G+LLFIG+++ P+G
Sbjct: 397 SGSLLFIGRLVRPKG 411
>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 3 [Homo sapiens]
Length = 390
Score = 128 bits (321), Expect = 1e-29
Identities = 100/393 (25%), Positives = 191/393 (48%), Gaps = 31/393 (7%)
Query: 51 VNKLAAAVSNFGYDLYRVRSSTSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYY 110
+N L+ A + F +DL++ + S N+ SP+S+ +AL + LGA+ T I + L++
Sbjct: 1 MNSLSEANTKFMFDLFQ-QFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHF 59
Query: 111 DLIS--------------SPDIHGTYKELLDTV--TAPQKNLKSASRIVFEKKLRIKSSF 154
D ++ S ++H +++LL + LK A+++ EK +
Sbjct: 60 DQVTENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEY 119
Query: 155 VAPLEKSYGTRPRVL--TGNPRLDLQEINNWVQAQMKGKLARSTKE--IPDEISILLLGV 210
+ ++K Y T + P ++IN+WV++Q K+ E I +++L+
Sbjct: 120 LDAIKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNA 179
Query: 211 AHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTG 270
+FKGQW KF+ T E F+ ++ + MM + L+ D+ K+ ++P G
Sbjct: 180 IYFKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLE-DVQAKVLEIPYKG 238
Query: 271 S-MSIIFFLPLKVTQNLTLIEESLTSEFIHDID--RELKTVQAVLTVPKLKLSYEGEVTK 327
+S+I LP ++ L +EE LT+E + + + ++ + L +P+ K+ ++
Sbjct: 239 KDLSMIVLLPNEI-DGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKD 297
Query: 328 SLQEMKLQSLFDSP-DFSKITG-KPIKLTQVEHRAGFEWNEDGA---GTTPSPGLQPAHL 382
+L+ M + +F+ D S +TG + + L+ V H+A E E+GA T G +
Sbjct: 298 TLRTMGMVDIFNGDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPT 357
Query: 383 TFPLDYHLNQPFIFVLRDTDTGALLFIGKILDP 415
+ ++H N PF+F +R T ++LF G+ P
Sbjct: 358 STNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390
>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 4 [Homo sapiens]
Length = 390
Score = 125 bits (313), Expect = 9e-29
Identities = 96/393 (24%), Positives = 190/393 (48%), Gaps = 31/393 (7%)
Query: 51 VNKLAAAVSNFGYDLYRVRSSTSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYY 110
+N L+ A + F +DL++ + S N+ SP+S+ +AL + LGA+ T I + L++
Sbjct: 1 MNSLSEANTKFMFDLFQ-QFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHF 59
Query: 111 DLIS--------------SPDIHGTYKELLD--TVTAPQKNLKSASRIVFEKKLRIKSSF 154
D ++ S ++H +++LL + LK A+++ EK + +
Sbjct: 60 DQVTENTTEKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEY 119
Query: 155 VAPLEKSYGT--RPRVLTGNPRLDLQEINNWVQAQMKGKLARSTKE--IPDEISILLLGV 210
+ ++K Y T P ++IN+WV++Q K+ + I ++ +++L+
Sbjct: 120 LDAIKKFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNA 179
Query: 211 AHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTG 270
+FKGQW KF T E F+ ++ V MM + + L D+ K+ ++P G
Sbjct: 180 IYFKGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQYNS-FNFALLEDVQAKVLEIPYKG 238
Query: 271 -SMSIIFFLPLKVTQNLTLIEESLTSEFIHDID--RELKTVQAVLTVPKLKLSYEGEVTK 327
+S+I LP ++ L +EE LT+E + + + ++ L +P+ K+ ++
Sbjct: 239 KDLSMIVLLPNEI-DGLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKD 297
Query: 328 SLQEMKLQSLFD-SPDFSKIT-GKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFP 385
+L+ M + ++F+ D S +T + +++V H+A E E+G + + L+ P
Sbjct: 298 TLRTMGMVNIFNGDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSP 357
Query: 386 L---DYHLNQPFIFVLRDTDTGALLFIGKILDP 415
++ N PF+F +R T ++LF G+ P
Sbjct: 358 STNEEFCCNHPFLFFIRQNKTNSILFYGRFSSP 390
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,012,409
Number of Sequences: 37866
Number of extensions: 718940
Number of successful extensions: 2537
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 2319
Number of HSP's gapped (non-prelim): 76
length of query: 418
length of database: 18,247,518
effective HSP length: 105
effective length of query: 313
effective length of database: 14,271,588
effective search space: 4467007044
effective search space used: 4467007044
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.