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Search of human proteins with 32454741
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32454741 serine (or cysteine) proteinase inhibitor, clade H,
member 1 precursor [Homo sapiens]
(418 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32454741 serine (or cysteine) proteinase inhibitor, clade H, ... 820 0.0
gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (... 182 4e-46
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s... 178 9e-45
gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (... 177 2e-44
gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (... 177 2e-44
gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (... 171 9e-43
gi|17998551 serine (or cysteine) proteinase inhibitor, clade B (... 169 3e-42
gi|4826902 serine (or cysteine) proteinase inhibitor, clade B (o... 163 2e-40
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o... 163 3e-40
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ... 160 2e-39
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom... 158 8e-39
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom... 158 8e-39
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom... 158 8e-39
gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom... 158 8e-39
gi|189163534 serine proteinase inhibitor, clade A, member 1 [Hom... 158 8e-39
gi|189163532 serine proteinase inhibitor, clade A, member 1 [Hom... 158 8e-39
gi|189163530 serine proteinase inhibitor, clade A, member 1 [Hom... 158 8e-39
gi|189163528 serine proteinase inhibitor, clade A, member 1 [Hom... 158 8e-39
gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo... 158 8e-39
gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo... 158 8e-39
gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo... 158 8e-39
gi|167860126 serine (or cysteine) proteinase inhibitor, clade B ... 155 5e-38
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (... 153 3e-37
gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Hom... 152 5e-37
gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member... 150 2e-36
gi|219689110 serine (or cysteine) proteinase inhibitor, clade B ... 147 1e-35
gi|4505595 serine (or cysteine) proteinase inhibitor, clade B (o... 147 1e-35
gi|170295807 neuroserpin precursor [Homo sapiens] 147 2e-35
gi|4826904 neuroserpin precursor [Homo sapiens] 147 2e-35
gi|27777657 serine (or cysteine) proteinase inhibitor, clade A (... 146 4e-35
>gi|32454741 serine (or cysteine) proteinase inhibitor, clade H,
member 1 precursor [Homo sapiens]
Length = 418
Score = 820 bits (2119), Expect = 0.0
Identities = 418/418 (100%), Positives = 418/418 (100%)
Query: 1 MRSLLLLSAFCLLEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAK 60
MRSLLLLSAFCLLEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAK
Sbjct: 1 MRSLLLLSAFCLLEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAK 60
Query: 61 DQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSN 120
DQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSN
Sbjct: 61 DQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSN 120
Query: 121 STARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQT 180
STARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQT
Sbjct: 121 STARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQT 180
Query: 181 TDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRT 240
TDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRT
Sbjct: 181 TDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRT 240
Query: 241 GLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQKK 300
GLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQKK
Sbjct: 241 GLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQKK 300
Query: 301 AVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELD 360
AVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELD
Sbjct: 301 AVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELD 360
Query: 361 TDGNPFDQDIYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRDEL 418
TDGNPFDQDIYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRDEL
Sbjct: 361 TDGNPFDQDIYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRDEL 418
>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 1 [Homo sapiens]
Length = 379
Score = 182 bits (463), Expect = 4e-46
Identities = 113/379 (29%), Positives = 203/379 (53%), Gaps = 15/379 (3%)
Query: 43 LAERSAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQL 102
L+ + A L+ A++++ NI +SP ++S++ +V LG + TA+Q +
Sbjct: 4 LSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNTV 63
Query: 103 RDEEVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKIN 162
EEVH+ L ++ A + KL +RLYG + +F +F+ S+++ Y + + ++
Sbjct: 64 --EEVHSRFQSLNADINKRGASYIL-KLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD 120
Query: 163 FRD-KRSALQSINEWAAQTTDGKLPEVTKD--VERTDGALLVNAMFFKPHWDEKFHHKMV 219
F+ A ++IN+W T+GK+PE+ V+ +LVNA++FK +W +KF +
Sbjct: 121 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEAT 180
Query: 220 DNRGFMVTRSYTVGVMMMHRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEP-- 277
N F + + V MM++ + Y E K +++E+P + S++IL+P +E
Sbjct: 181 TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDES 240
Query: 278 --LERLEKLLTKEQLKIWMG--KMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKN 333
L+++E+ LT E+L W + V +SLP+ +E ++ L LA LG+ + + +
Sbjct: 241 TGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS 300
Query: 334 KADLSRMSGKKDLYLASVFHATAFELDTDGNPFDQDIYGREE---LRSPKLFYADHPFIF 390
KADLS MSG +D++++ + H + E++ +G G L + F ADHPF+F
Sbjct: 301 KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLF 360
Query: 391 LVRDTQSGSLLFIGRLVRP 409
+R SGS+LF+GR P
Sbjct: 361 FIRHNSSGSILFLGRFSSP 379
>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
sapiens]
Length = 376
Score = 178 bits (451), Expect = 9e-45
Identities = 112/377 (29%), Positives = 186/377 (49%), Gaps = 12/377 (3%)
Query: 42 TLAERSAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQ 101
TL+ S A L + + +D N+ SPV ++S+L +V LG K TA+Q LS
Sbjct: 3 TLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSLNT 62
Query: 102 LRDEEVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKI 161
+E++H LL + N + +RL+G + F F S Q Y+ E ++
Sbjct: 63 --EEDIHRAFQSLLTEV-NKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKEL 119
Query: 162 NF-RDKRSALQSINEWAAQTTDGKLPEVT--KDVERTDGALLVNAMFFKPHWDEKFHHKM 218
+F R + + IN W ++ T+GK+ E+ ++ +LVNA++FK W+E F
Sbjct: 120 SFIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETY 179
Query: 219 VDNRGFMVTRSYTVGVMMMHRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPL 278
F + + V MM++ + + + Q++E+P A K SL++L+P L
Sbjct: 180 TREMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGVEL 239
Query: 279 ERLEKLLTKEQLKIWMGK--MQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKAD 336
+EK LT E+L W M+ V + LPK ++ +D++ L LG+ +A + KAD
Sbjct: 240 STVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKAD 299
Query: 337 LSRMSGKKDLYLASVFHATAFELDTDGNPFDQD----IYGREELRSPKLFYADHPFIFLV 392
LS MS ++DL L+ H + E++ +G + + S F ADHPF+F +
Sbjct: 300 LSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFLFFI 359
Query: 393 RDTQSGSLLFIGRLVRP 409
R ++ S+LF GR P
Sbjct: 360 RHNRANSILFCGRFSSP 376
>gi|38504669 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 177 bits (449), Expect = 2e-44
Identities = 114/375 (30%), Positives = 186/375 (49%), Gaps = 12/375 (3%)
Query: 43 LAERSAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQL 102
L E + A SL++ + ++ N+ SP+ ++S+L +V +G K +TA+Q L
Sbjct: 4 LCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL--Y 61
Query: 103 RDEEVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKIN 162
+D ++H G LL + N T + +RL+G + F DF ++ Y E +++
Sbjct: 62 KDGDIHRGFQSLLSEV-NRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120
Query: 163 F-RDKRSALQSINEWAAQTTDGKLPEVTK--DVERTDGALLVNAMFFKPHWDEKFHHKMV 219
F D + IN+W A+ T+GK+ EV V+ +LVNA++FK W+E+F K
Sbjct: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180
Query: 220 DNRGFMVTRSYTVGVMMMHRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLE 279
F MM Y DE Q++E+P + S++IL+P L
Sbjct: 181 RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHT-QVLELPYVEEELSMVILLPDDNTDLA 239
Query: 280 RLEKLLTKEQLKIWMG--KMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADL 337
+EK LT E+ K W K+ K V + LP+ +E ++DL+ L LG+ +A D+ KAD
Sbjct: 240 VVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADF 299
Query: 338 SRMSGKKDLYLASVFHATAFELDTDGNPFDQDIYGREELRSPKL---FYADHPFIFLVRD 394
S MS +K++ L+ V H E++ +G R ++ F ADHPF+F +R
Sbjct: 300 SGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRH 359
Query: 395 TQSGSLLFIGRLVRP 409
++ +LF GR P
Sbjct: 360 HKTNCILFCGRFSSP 374
>gi|38504673 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 177 bits (449), Expect = 2e-44
Identities = 114/375 (30%), Positives = 186/375 (49%), Gaps = 12/375 (3%)
Query: 43 LAERSAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQL 102
L E + A SL++ + ++ N+ SP+ ++S+L +V +G K +TA+Q L
Sbjct: 4 LCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL--Y 61
Query: 103 RDEEVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKIN 162
+D ++H G LL + N T + +RL+G + F DF ++ Y E +++
Sbjct: 62 KDGDIHRGFQSLLSEV-NRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120
Query: 163 F-RDKRSALQSINEWAAQTTDGKLPEVTK--DVERTDGALLVNAMFFKPHWDEKFHHKMV 219
F D + IN+W A+ T+GK+ EV V+ +LVNA++FK W+E+F K
Sbjct: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180
Query: 220 DNRGFMVTRSYTVGVMMMHRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLE 279
F MM Y DE Q++E+P + S++IL+P L
Sbjct: 181 RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHT-QVLELPYVEEELSMVILLPDDNTDLA 239
Query: 280 RLEKLLTKEQLKIWMG--KMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADL 337
+EK LT E+ K W K+ K V + LP+ +E ++DL+ L LG+ +A D+ KAD
Sbjct: 240 VVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADF 299
Query: 338 SRMSGKKDLYLASVFHATAFELDTDGNPFDQDIYGREELRSPKL---FYADHPFIFLVRD 394
S MS +K++ L+ V H E++ +G R ++ F ADHPF+F +R
Sbjct: 300 SGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRH 359
Query: 395 TQSGSLLFIGRLVRP 409
++ +LF GR P
Sbjct: 360 HKTNCILFCGRFSSP 374
>gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 6 [Homo sapiens]
Length = 376
Score = 171 bits (434), Expect = 9e-43
Identities = 111/376 (29%), Positives = 196/376 (52%), Gaps = 12/376 (3%)
Query: 43 LAERSAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQL 102
LAE + A +L + + KD + +N+ SP+ ++ +L +V +G K TA+Q +LS +
Sbjct: 4 LAEANGTFALNLLKTLGKDNS-KNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKS 62
Query: 103 RDE-EVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKI 161
++H G LL + N T ++ +RL+G S F F S ++ Y E ++
Sbjct: 63 GGGGDIHQGFQSLLTEV-NKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEEL 121
Query: 162 NFRDK-RSALQSINEWAAQTTDGKLPEVTK--DVERTDGALLVNAMFFKPHWDEKFHHKM 218
+F + + IN W A+ T+GK+ E+ V+ +LVNA++F+ +WDE+F +
Sbjct: 122 DFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKEN 181
Query: 219 VDNRGFMVTRSYTVGVMMMHRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPL 278
+ R F V+++ V MM + + + QI+ +P K ++II++P L
Sbjct: 182 TEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDL 241
Query: 279 ERLEKLLTKEQLKIW--MGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKAD 336
+EK LT E+ W + M ++ V +SLP+ +E ++D++ L LG+T+A + KAD
Sbjct: 242 RTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKAD 301
Query: 337 LSRMSGKKDLYLASVFHATAFELDTDGNPFDQDIYGREELRSPKL---FYADHPFIFLVR 393
S MS + DL L+ V H + E++ +G +R + F ADHPF+F ++
Sbjct: 302 FSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQ 360
Query: 394 DTQSGSLLFIGRLVRP 409
+++ +LF GR P
Sbjct: 361 HSKTNGILFCGRFSSP 376
>gi|17998551 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 12 [Homo sapiens]
Length = 405
Score = 169 bits (429), Expect = 3e-42
Identities = 114/404 (28%), Positives = 195/404 (48%), Gaps = 37/404 (9%)
Query: 42 TLAERSAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQ 101
+L + F L+Q + KD +NI SP+ ++++LG+V LG ++ +A Q VL +
Sbjct: 3 SLVTANTKFCFDLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHFNE 62
Query: 102 LRDEE------------------------VHAGLGELLRSLSNSTARNVTWKLGSRLYGP 137
E V G+LL L + T + +RLYG
Sbjct: 63 FSQNESKEPDPCLKSNKQKAGSLNNESGLVSCYFGQLLSKLDRIKT-DYTLSIANRLYGE 121
Query: 138 SSVSFADDFVRSSKQHYNCEHSKINF-RDKRSALQSINEWAAQTTDGKLPEV-TKDVERT 195
+++ Q Y+ ++F ++ + Q IN W + GK+ E+ +KD
Sbjct: 122 QEFPICQEYLDGVIQFYHTTIESVDFQKNPEKSRQEINFWVECQSQGKIKELFSKDAINA 181
Query: 196 DGAL-LVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRTGLYNYYDDEKEKLQ 254
+ L LVNA++FK W+ F H+ + F + + V MM + GLY E+ K Q
Sbjct: 182 ETVLVLVNAVYFKAKWETYFDHENTVDAPFCLNANENKSVKMMTQKGLYRIGFIEEVKAQ 241
Query: 255 IVEMPLAHKLSSLIILMPHH----VEPLERLEKLLTKEQLKIWMGK--MQKKAVAISLPK 308
I+EM S+ +L+P H ++ LE LE+ +T E++ W M +++V +S P+
Sbjct: 242 ILEMRYTKGKLSMFVLLPSHSKDNLKGLEELERKITYEKMVAWSSSENMSEESVVLSFPR 301
Query: 309 GVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELDTDGN---P 365
+E ++DL L +G+T+ D+ +ADL+ +S +LYL+ + H T E+D +G
Sbjct: 302 FTLEDSYDLNSILQDMGITDIFDETRADLTGISPSPNLYLSKIIHKTFVEVDENGTQAAA 361
Query: 366 FDQDIYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRP 409
+ LRS F A+HPF+F +R ++ ++LF GR+ P
Sbjct: 362 ATGAVVSERSLRSWVEFNANHPFLFFIRHNKTQTILFYGRVCSP 405
>gi|4826902 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 10 [Homo sapiens]
Length = 397
Score = 163 bits (413), Expect = 2e-40
Identities = 113/397 (28%), Positives = 199/397 (50%), Gaps = 31/397 (7%)
Query: 42 TLAERSAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLS--- 98
+LA A L + +A+ +NI S +++SL +V LG K TTA+Q VL
Sbjct: 3 SLATSINQFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNR 62
Query: 99 ---------AEQLR--------DEEVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVS 141
+E+ R EE+H+ L+ + + K + +YG + +
Sbjct: 63 DQGVKCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPND-DYLLKTANAIYGEKTYA 121
Query: 142 FADDFVRSSKQHYNCEHSKINFRDKRSALQS-INEWAAQTTDGKLPEVTKD--VERTDGA 198
F + ++ K ++ E +NF + ++ IN W + T+GK+ + D V+ T
Sbjct: 122 FHNKYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTRM 181
Query: 199 LLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRTGLYNYYDDEKEKLQIVEM 258
+LVNA++FK W+ +F + + F + + + V MM + + EK K +++
Sbjct: 182 ILVNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQL 241
Query: 259 PLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMG--KMQKKAVAISLPKGVVEVTHD 316
+ SL+IL+P + LE+LEK +T E+L W M+ V + LPK +E ++D
Sbjct: 242 YYKSRDLSLLILLPEDINGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKLEDSYD 301
Query: 317 LQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELDTDGNPFDQDIYGRE-- 374
L+ L+ +G+++A ++KAD S MS ++L+L++VFH E++ G G E
Sbjct: 302 LKSTLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAG-SGSEID 360
Query: 375 -ELRSPKL-FYADHPFIFLVRDTQSGSLLFIGRLVRP 409
+R P + F A+HPF+F +R ++ ++LF GRL P
Sbjct: 361 IRIRVPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP 397
>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 3 [Homo sapiens]
Length = 390
Score = 163 bits (412), Expect = 3e-40
Identities = 107/391 (27%), Positives = 195/391 (49%), Gaps = 26/391 (6%)
Query: 42 TLAERSAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQ 101
+L+E + F L+Q K + NI SP+ + S+LG+V LG K TA Q K VL +Q
Sbjct: 3 SLSEANTKFMFDLFQQFRKSKE-NNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQ 61
Query: 102 L--------------RDEEVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFV 147
+ R VH +LL + ST K+ ++L+G + F +++
Sbjct: 62 VTENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDA-YELKIANKLFGEKTYLFLQEYL 120
Query: 148 RSSKQHYNCEHSKINFRDK-RSALQSINEWAAQTTDGKLPEVTKD--VERTDGALLVNAM 204
+ K+ Y ++F + + + IN W T+ K+ + + + +LVNA+
Sbjct: 121 DAIKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAI 180
Query: 205 FFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRTGLYNYYDDEKEKLQIVEMPLAHKL 264
+FK W++KF+ + F ++ + MM + +++ E + +++E+P K
Sbjct: 181 YFKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGKD 240
Query: 265 SSLIILMPHHVEPLERLEKLLTKEQLKIW--MGKMQKKAVAISLPKGVVEVTHDLQKHLA 322
S+I+L+P+ ++ L++LE+ LT E+L W + M++ V + LP+ VE ++DL+ L
Sbjct: 241 LSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLR 300
Query: 323 GLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELDTDGNPFDQDI----YGREELRS 378
+G+ + I ADLS M+G + L L+ V H E+ +G +G +
Sbjct: 301 TMGMVD-IFNGDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTST 359
Query: 379 PKLFYADHPFIFLVRDTQSGSLLFIGRLVRP 409
+ F+ +HPF+F +R ++ S+LF GR P
Sbjct: 360 NEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390
>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 5 [Homo
sapiens]
Length = 406
Score = 160 bits (405), Expect = 2e-39
Identities = 108/377 (28%), Positives = 192/377 (50%), Gaps = 16/377 (4%)
Query: 41 ATLAERSA-GLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQ--AKAVL 97
AT+A S F LY+A+A ++I SPV ++ SL ++SLG ++T Q L
Sbjct: 38 ATVAPSSRRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGL 97
Query: 98 SAEQLRDEEVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCE 157
+ ++ ++E+H G +LL+ L N LG+ L+ V D FV + K Y +
Sbjct: 98 NLQKSSEKELHRGFQQLLQEL-NQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLAD 156
Query: 158 HSKINFRDKRSALQSINEWAAQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHK 217
NFRD A++ IN++ A+ T GK+ ++ K+++ ++VN +FFK W+ F+HK
Sbjct: 157 TFPTNFRDSAGAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHK 216
Query: 218 MVDNRGFMVTRSYTVGVMMMHRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEP 277
+ F VT V V MM R Y+Y D ++V +P ++L IL
Sbjct: 217 GTQEQDFYVTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSE--GK 274
Query: 278 LERLEKLLTKEQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADL 337
++++E L+++ L+ W+ +K+ + + LPK +E ++ L+K L LG++ + ADL
Sbjct: 275 MQQVENGLSEKTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSH-ADL 333
Query: 338 SRMSGKKDLYLASVFHATAFELDTDGNPFDQD-----IYGREELRSPKLFYADHPFIFLV 392
S +S ++ ++ + H E+D G + L S +L + + PF+ +
Sbjct: 334 SGISNHSNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVF-NRPFLMFI 392
Query: 393 RDTQSGSLLFIGRLVRP 409
D ++LF+G++ RP
Sbjct: 393 VD---NNILFLGKVNRP 406
>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 158 bits (400), Expect = 8e-39
Identities = 115/411 (27%), Positives = 199/411 (48%), Gaps = 9/411 (2%)
Query: 4 LLLLSAFCLLEAALAAEVKKPAAAAAPGTA--EKLSPKAATLAERSAGLAFSLYQAMAKD 61
+LLL+ C L AE + AA T+ ++ P + A AFSLY+ +A
Sbjct: 9 ILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 62 QAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAE--QLRDEEVHAGLGELLRSLS 119
NI SPV +A++ ++SLG KA T + L+ ++ + ++H G ELLR+L
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTL- 127
Query: 120 NSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQ 179
N + G+ L+ + D F+ K+ Y+ E +NF D A + IN++ +
Sbjct: 128 NQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEK 187
Query: 180 TTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHR 239
T GK+ ++ K+++R LVN +FFK W+ F K + F V + TV V MM R
Sbjct: 188 GTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKR 247
Query: 240 TGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQK 299
G++N +K ++ M +++ L L+ LE LT + + ++ +
Sbjct: 248 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQHLENELTHDIITKFLENEDR 305
Query: 300 KAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFEL 359
++ ++ LPK + T+DL+ L LG+T+ + N ADLS ++ + L L+ H +
Sbjct: 306 RSASLHLPKLSITGTYDLKSVLGQLGITK-VFSNGADLSGVTEEAPLKLSKAVHKAVLTI 364
Query: 360 DTDGNPFDQDIYGRE-ELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRP 409
D G ++ + P + PF+FL+ + + S LF+G++V P
Sbjct: 365 DEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 158 bits (400), Expect = 8e-39
Identities = 115/411 (27%), Positives = 199/411 (48%), Gaps = 9/411 (2%)
Query: 4 LLLLSAFCLLEAALAAEVKKPAAAAAPGTA--EKLSPKAATLAERSAGLAFSLYQAMAKD 61
+LLL+ C L AE + AA T+ ++ P + A AFSLY+ +A
Sbjct: 9 ILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 62 QAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAE--QLRDEEVHAGLGELLRSLS 119
NI SPV +A++ ++SLG KA T + L+ ++ + ++H G ELLR+L
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTL- 127
Query: 120 NSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQ 179
N + G+ L+ + D F+ K+ Y+ E +NF D A + IN++ +
Sbjct: 128 NQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEK 187
Query: 180 TTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHR 239
T GK+ ++ K+++R LVN +FFK W+ F K + F V + TV V MM R
Sbjct: 188 GTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKR 247
Query: 240 TGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQK 299
G++N +K ++ M +++ L L+ LE LT + + ++ +
Sbjct: 248 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQHLENELTHDIITKFLENEDR 305
Query: 300 KAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFEL 359
++ ++ LPK + T+DL+ L LG+T+ + N ADLS ++ + L L+ H +
Sbjct: 306 RSASLHLPKLSITGTYDLKSVLGQLGITK-VFSNGADLSGVTEEAPLKLSKAVHKAVLTI 364
Query: 360 DTDGNPFDQDIYGRE-ELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRP 409
D G ++ + P + PF+FL+ + + S LF+G++V P
Sbjct: 365 DEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 158 bits (400), Expect = 8e-39
Identities = 115/411 (27%), Positives = 199/411 (48%), Gaps = 9/411 (2%)
Query: 4 LLLLSAFCLLEAALAAEVKKPAAAAAPGTA--EKLSPKAATLAERSAGLAFSLYQAMAKD 61
+LLL+ C L AE + AA T+ ++ P + A AFSLY+ +A
Sbjct: 9 ILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 62 QAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAE--QLRDEEVHAGLGELLRSLS 119
NI SPV +A++ ++SLG KA T + L+ ++ + ++H G ELLR+L
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTL- 127
Query: 120 NSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQ 179
N + G+ L+ + D F+ K+ Y+ E +NF D A + IN++ +
Sbjct: 128 NQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEK 187
Query: 180 TTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHR 239
T GK+ ++ K+++R LVN +FFK W+ F K + F V + TV V MM R
Sbjct: 188 GTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKR 247
Query: 240 TGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQK 299
G++N +K ++ M +++ L L+ LE LT + + ++ +
Sbjct: 248 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQHLENELTHDIITKFLENEDR 305
Query: 300 KAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFEL 359
++ ++ LPK + T+DL+ L LG+T+ + N ADLS ++ + L L+ H +
Sbjct: 306 RSASLHLPKLSITGTYDLKSVLGQLGITK-VFSNGADLSGVTEEAPLKLSKAVHKAVLTI 364
Query: 360 DTDGNPFDQDIYGRE-ELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRP 409
D G ++ + P + PF+FL+ + + S LF+G++V P
Sbjct: 365 DEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 158 bits (400), Expect = 8e-39
Identities = 115/411 (27%), Positives = 199/411 (48%), Gaps = 9/411 (2%)
Query: 4 LLLLSAFCLLEAALAAEVKKPAAAAAPGTA--EKLSPKAATLAERSAGLAFSLYQAMAKD 61
+LLL+ C L AE + AA T+ ++ P + A AFSLY+ +A
Sbjct: 9 ILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 62 QAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAE--QLRDEEVHAGLGELLRSLS 119
NI SPV +A++ ++SLG KA T + L+ ++ + ++H G ELLR+L
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTL- 127
Query: 120 NSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQ 179
N + G+ L+ + D F+ K+ Y+ E +NF D A + IN++ +
Sbjct: 128 NQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEK 187
Query: 180 TTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHR 239
T GK+ ++ K+++R LVN +FFK W+ F K + F V + TV V MM R
Sbjct: 188 GTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKR 247
Query: 240 TGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQK 299
G++N +K ++ M +++ L L+ LE LT + + ++ +
Sbjct: 248 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQHLENELTHDIITKFLENEDR 305
Query: 300 KAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFEL 359
++ ++ LPK + T+DL+ L LG+T+ + N ADLS ++ + L L+ H +
Sbjct: 306 RSASLHLPKLSITGTYDLKSVLGQLGITK-VFSNGADLSGVTEEAPLKLSKAVHKAVLTI 364
Query: 360 DTDGNPFDQDIYGRE-ELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRP 409
D G ++ + P + PF+FL+ + + S LF+G++V P
Sbjct: 365 DEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163534 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 158 bits (400), Expect = 8e-39
Identities = 115/411 (27%), Positives = 199/411 (48%), Gaps = 9/411 (2%)
Query: 4 LLLLSAFCLLEAALAAEVKKPAAAAAPGTA--EKLSPKAATLAERSAGLAFSLYQAMAKD 61
+LLL+ C L AE + AA T+ ++ P + A AFSLY+ +A
Sbjct: 9 ILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 62 QAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAE--QLRDEEVHAGLGELLRSLS 119
NI SPV +A++ ++SLG KA T + L+ ++ + ++H G ELLR+L
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTL- 127
Query: 120 NSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQ 179
N + G+ L+ + D F+ K+ Y+ E +NF D A + IN++ +
Sbjct: 128 NQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEK 187
Query: 180 TTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHR 239
T GK+ ++ K+++R LVN +FFK W+ F K + F V + TV V MM R
Sbjct: 188 GTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKR 247
Query: 240 TGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQK 299
G++N +K ++ M +++ L L+ LE LT + + ++ +
Sbjct: 248 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQHLENELTHDIITKFLENEDR 305
Query: 300 KAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFEL 359
++ ++ LPK + T+DL+ L LG+T+ + N ADLS ++ + L L+ H +
Sbjct: 306 RSASLHLPKLSITGTYDLKSVLGQLGITK-VFSNGADLSGVTEEAPLKLSKAVHKAVLTI 364
Query: 360 DTDGNPFDQDIYGRE-ELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRP 409
D G ++ + P + PF+FL+ + + S LF+G++V P
Sbjct: 365 DEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163532 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 158 bits (400), Expect = 8e-39
Identities = 115/411 (27%), Positives = 199/411 (48%), Gaps = 9/411 (2%)
Query: 4 LLLLSAFCLLEAALAAEVKKPAAAAAPGTA--EKLSPKAATLAERSAGLAFSLYQAMAKD 61
+LLL+ C L AE + AA T+ ++ P + A AFSLY+ +A
Sbjct: 9 ILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 62 QAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAE--QLRDEEVHAGLGELLRSLS 119
NI SPV +A++ ++SLG KA T + L+ ++ + ++H G ELLR+L
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTL- 127
Query: 120 NSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQ 179
N + G+ L+ + D F+ K+ Y+ E +NF D A + IN++ +
Sbjct: 128 NQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEK 187
Query: 180 TTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHR 239
T GK+ ++ K+++R LVN +FFK W+ F K + F V + TV V MM R
Sbjct: 188 GTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKR 247
Query: 240 TGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQK 299
G++N +K ++ M +++ L L+ LE LT + + ++ +
Sbjct: 248 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQHLENELTHDIITKFLENEDR 305
Query: 300 KAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFEL 359
++ ++ LPK + T+DL+ L LG+T+ + N ADLS ++ + L L+ H +
Sbjct: 306 RSASLHLPKLSITGTYDLKSVLGQLGITK-VFSNGADLSGVTEEAPLKLSKAVHKAVLTI 364
Query: 360 DTDGNPFDQDIYGRE-ELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRP 409
D G ++ + P + PF+FL+ + + S LF+G++V P
Sbjct: 365 DEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163530 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 158 bits (400), Expect = 8e-39
Identities = 115/411 (27%), Positives = 199/411 (48%), Gaps = 9/411 (2%)
Query: 4 LLLLSAFCLLEAALAAEVKKPAAAAAPGTA--EKLSPKAATLAERSAGLAFSLYQAMAKD 61
+LLL+ C L AE + AA T+ ++ P + A AFSLY+ +A
Sbjct: 9 ILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 62 QAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAE--QLRDEEVHAGLGELLRSLS 119
NI SPV +A++ ++SLG KA T + L+ ++ + ++H G ELLR+L
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTL- 127
Query: 120 NSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQ 179
N + G+ L+ + D F+ K+ Y+ E +NF D A + IN++ +
Sbjct: 128 NQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEK 187
Query: 180 TTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHR 239
T GK+ ++ K+++R LVN +FFK W+ F K + F V + TV V MM R
Sbjct: 188 GTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKR 247
Query: 240 TGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQK 299
G++N +K ++ M +++ L L+ LE LT + + ++ +
Sbjct: 248 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQHLENELTHDIITKFLENEDR 305
Query: 300 KAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFEL 359
++ ++ LPK + T+DL+ L LG+T+ + N ADLS ++ + L L+ H +
Sbjct: 306 RSASLHLPKLSITGTYDLKSVLGQLGITK-VFSNGADLSGVTEEAPLKLSKAVHKAVLTI 364
Query: 360 DTDGNPFDQDIYGRE-ELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRP 409
D G ++ + P + PF+FL+ + + S LF+G++V P
Sbjct: 365 DEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163528 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 158 bits (400), Expect = 8e-39
Identities = 115/411 (27%), Positives = 199/411 (48%), Gaps = 9/411 (2%)
Query: 4 LLLLSAFCLLEAALAAEVKKPAAAAAPGTA--EKLSPKAATLAERSAGLAFSLYQAMAKD 61
+LLL+ C L AE + AA T+ ++ P + A AFSLY+ +A
Sbjct: 9 ILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 62 QAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAE--QLRDEEVHAGLGELLRSLS 119
NI SPV +A++ ++SLG KA T + L+ ++ + ++H G ELLR+L
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTL- 127
Query: 120 NSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQ 179
N + G+ L+ + D F+ K+ Y+ E +NF D A + IN++ +
Sbjct: 128 NQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEK 187
Query: 180 TTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHR 239
T GK+ ++ K+++R LVN +FFK W+ F K + F V + TV V MM R
Sbjct: 188 GTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKR 247
Query: 240 TGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQK 299
G++N +K ++ M +++ L L+ LE LT + + ++ +
Sbjct: 248 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQHLENELTHDIITKFLENEDR 305
Query: 300 KAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFEL 359
++ ++ LPK + T+DL+ L LG+T+ + N ADLS ++ + L L+ H +
Sbjct: 306 RSASLHLPKLSITGTYDLKSVLGQLGITK-VFSNGADLSGVTEEAPLKLSKAVHKAVLTI 364
Query: 360 DTDGNPFDQDIYGRE-ELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRP 409
D G ++ + P + PF+FL+ + + S LF+G++V P
Sbjct: 365 DEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 158 bits (400), Expect = 8e-39
Identities = 115/411 (27%), Positives = 199/411 (48%), Gaps = 9/411 (2%)
Query: 4 LLLLSAFCLLEAALAAEVKKPAAAAAPGTA--EKLSPKAATLAERSAGLAFSLYQAMAKD 61
+LLL+ C L AE + AA T+ ++ P + A AFSLY+ +A
Sbjct: 9 ILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 62 QAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAE--QLRDEEVHAGLGELLRSLS 119
NI SPV +A++ ++SLG KA T + L+ ++ + ++H G ELLR+L
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTL- 127
Query: 120 NSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQ 179
N + G+ L+ + D F+ K+ Y+ E +NF D A + IN++ +
Sbjct: 128 NQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEK 187
Query: 180 TTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHR 239
T GK+ ++ K+++R LVN +FFK W+ F K + F V + TV V MM R
Sbjct: 188 GTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKR 247
Query: 240 TGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQK 299
G++N +K ++ M +++ L L+ LE LT + + ++ +
Sbjct: 248 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQHLENELTHDIITKFLENEDR 305
Query: 300 KAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFEL 359
++ ++ LPK + T+DL+ L LG+T+ + N ADLS ++ + L L+ H +
Sbjct: 306 RSASLHLPKLSITGTYDLKSVLGQLGITK-VFSNGADLSGVTEEAPLKLSKAVHKAVLTI 364
Query: 360 DTDGNPFDQDIYGRE-ELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRP 409
D G ++ + P + PF+FL+ + + S LF+G++V P
Sbjct: 365 DEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 158 bits (400), Expect = 8e-39
Identities = 115/411 (27%), Positives = 199/411 (48%), Gaps = 9/411 (2%)
Query: 4 LLLLSAFCLLEAALAAEVKKPAAAAAPGTA--EKLSPKAATLAERSAGLAFSLYQAMAKD 61
+LLL+ C L AE + AA T+ ++ P + A AFSLY+ +A
Sbjct: 9 ILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 62 QAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAE--QLRDEEVHAGLGELLRSLS 119
NI SPV +A++ ++SLG KA T + L+ ++ + ++H G ELLR+L
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTL- 127
Query: 120 NSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQ 179
N + G+ L+ + D F+ K+ Y+ E +NF D A + IN++ +
Sbjct: 128 NQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEK 187
Query: 180 TTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHR 239
T GK+ ++ K+++R LVN +FFK W+ F K + F V + TV V MM R
Sbjct: 188 GTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKR 247
Query: 240 TGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQK 299
G++N +K ++ M +++ L L+ LE LT + + ++ +
Sbjct: 248 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQHLENELTHDIITKFLENEDR 305
Query: 300 KAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFEL 359
++ ++ LPK + T+DL+ L LG+T+ + N ADLS ++ + L L+ H +
Sbjct: 306 RSASLHLPKLSITGTYDLKSVLGQLGITK-VFSNGADLSGVTEEAPLKLSKAVHKAVLTI 364
Query: 360 DTDGNPFDQDIYGRE-ELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRP 409
D G ++ + P + PF+FL+ + + S LF+G++V P
Sbjct: 365 DEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 158 bits (400), Expect = 8e-39
Identities = 115/411 (27%), Positives = 199/411 (48%), Gaps = 9/411 (2%)
Query: 4 LLLLSAFCLLEAALAAEVKKPAAAAAPGTA--EKLSPKAATLAERSAGLAFSLYQAMAKD 61
+LLL+ C L AE + AA T+ ++ P + A AFSLY+ +A
Sbjct: 9 ILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 62 QAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAE--QLRDEEVHAGLGELLRSLS 119
NI SPV +A++ ++SLG KA T + L+ ++ + ++H G ELLR+L
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTL- 127
Query: 120 NSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQ 179
N + G+ L+ + D F+ K+ Y+ E +NF D A + IN++ +
Sbjct: 128 NQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEK 187
Query: 180 TTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHR 239
T GK+ ++ K+++R LVN +FFK W+ F K + F V + TV V MM R
Sbjct: 188 GTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKR 247
Query: 240 TGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQK 299
G++N +K ++ M +++ L L+ LE LT + + ++ +
Sbjct: 248 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQHLENELTHDIITKFLENEDR 305
Query: 300 KAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFEL 359
++ ++ LPK + T+DL+ L LG+T+ + N ADLS ++ + L L+ H +
Sbjct: 306 RSASLHLPKLSITGTYDLKSVLGQLGITK-VFSNGADLSGVTEEAPLKLSKAVHKAVLTI 364
Query: 360 DTDGNPFDQDIYGRE-ELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRP 409
D G ++ + P + PF+FL+ + + S LF+G++V P
Sbjct: 365 DEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|167860126 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 5 [Homo sapiens]
Length = 375
Score = 155 bits (393), Expect = 5e-38
Identities = 109/372 (29%), Positives = 182/372 (48%), Gaps = 13/372 (3%)
Query: 47 SAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEE 106
++ A L++ + + + + N+L SP+ +++SL L +G K TA++ VL E ++D
Sbjct: 8 NSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVKD-- 65
Query: 107 VHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDK 166
V G + + S N + + KL RLY S++ + +F+ S+K+ Y E ++F+DK
Sbjct: 66 VPFGF-QTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDK 124
Query: 167 RSALQS-INEWAAQTTDGKLPEVTKDVERTDGA--LLVNAMFFKPHWDEKFHHKMVDNRG 223
+ IN TDG + D D L+VNA +F W +KF
Sbjct: 125 LEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECP 184
Query: 224 FMVTRSYTVGVMMMHRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEP----LE 279
F V ++ T V MM+ + + + +I+E+P +K S+ IL+P VE LE
Sbjct: 185 FRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDESTGLE 244
Query: 280 RLEKLLTKEQLKIWM--GKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADL 337
++EK L E L W M V +S+PK VE D + L LGL ++ +D
Sbjct: 245 KIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSDF 304
Query: 338 SRMSGKKDLYLASVFHATAFELDTDGNPFDQDIYGREELRSPKLFYADHPFIFLVRDTQS 397
S MS K + L++V H E+ DG ++ G L+ ADHPFI+++R ++
Sbjct: 305 SGMSETKGVALSNVIHKVCLEITEDGGD-SIEVPGARILQHKDELNADHPFIYIIRHNKT 363
Query: 398 GSLLFIGRLVRP 409
+++F G+ P
Sbjct: 364 RNIIFFGKFCSP 375
>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 4 [Homo sapiens]
Length = 390
Score = 153 bits (386), Expect = 3e-37
Identities = 109/391 (27%), Positives = 187/391 (47%), Gaps = 26/391 (6%)
Query: 42 TLAERSAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQ 101
+L+E + F L+Q K + NI SP+ + S+LG+V LG K TA Q VL +Q
Sbjct: 3 SLSEANTKFMFDLFQQFRKSKE-NNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQ 61
Query: 102 L--------------RDEEVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFV 147
+ R VH +LL + ST K+ ++L+G + F +++
Sbjct: 62 VTENTTEKAATYHVDRSGNVHHQFQKLLTEFNKSTDA-YELKIANKLFGEKTYQFLQEYL 120
Query: 148 RSSKQHYNCEHSKINFRDK-RSALQSINEWAAQTTDGKLPEVTKD--VERTDGALLVNAM 204
+ K+ Y +F + + + IN W T+ K+ + D + +LVNA+
Sbjct: 121 DAIKKFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAI 180
Query: 205 FFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRTGLYNYYDDEKEKLQIVEMPLAHKL 264
+FK W+ KF + F ++ V MM + +N+ E + +++E+P K
Sbjct: 181 YFKGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGKD 240
Query: 265 SSLIILMPHHVEPLERLEKLLTKEQLKIW--MGKMQKKAVAISLPKGVVEVTHDLQKHLA 322
S+I+L+P+ ++ L++LE+ LT E+L W + M++ V + LP+ +E ++DL+ L
Sbjct: 241 LSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLR 300
Query: 323 GLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELDTDG-NPFDQDIYGREELRSPKL 381
+G+ I ADLS M+ L ++ V H E+ +G EL SP
Sbjct: 301 TMGMVN-IFNGDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSPST 359
Query: 382 ---FYADHPFIFLVRDTQSGSLLFIGRLVRP 409
F +HPF+F +R ++ S+LF GR P
Sbjct: 360 NEEFCCNHPFLFFIRQNKTNSILFYGRFSSP 390
>gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Homo
sapiens]
Length = 392
Score = 152 bits (384), Expect = 5e-37
Identities = 98/391 (25%), Positives = 182/391 (46%), Gaps = 24/391 (6%)
Query: 42 TLAERSAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQ 101
+L+ + +++ + + +NI S + + +L +V LG + T Q + VL
Sbjct: 3 SLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSH 62
Query: 102 LRDE---------------EVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDF 146
D +H+ G + N N T + +RLYG +++F +
Sbjct: 63 TVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQI-NQPDSNCTLSIANRLYGTKTMAFHQQY 121
Query: 147 VRSSKQHYNCEHSKINFRDK-RSALQSINEWAAQTTDGKLPEV--TKDVERTDGALLVNA 203
+ S++ Y ++F ++IN W T+GK+ + ++ + +LVNA
Sbjct: 122 LSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNA 181
Query: 204 MFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRTGLYNYYDDEKEKLQIVEMPLAHK 263
++FK W KF + F ++ V V MM++ G + ++ ++Q++E+P +
Sbjct: 182 IYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNN 241
Query: 264 LSSLIILMPHHVEPLERLEKLLTKEQLKIW--MGKMQKKAVAISLPKGVVEVTHDLQKHL 321
S+IIL+P + L+++EK L W M ++ V + LP+ +E ++L L
Sbjct: 242 KLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLL 301
Query: 322 AGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELDTDGN---PFDQDIYGREELRS 378
LG+T+ ++ KADLS MS K LYL+ H + ++ +G D + L
Sbjct: 302 KSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPM 361
Query: 379 PKLFYADHPFIFLVRDTQSGSLLFIGRLVRP 409
F A+HPF+F +R T + ++LF G+L P
Sbjct: 362 RAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
>gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member 2
[Homo sapiens]
Length = 405
Score = 150 bits (379), Expect = 2e-36
Identities = 102/384 (26%), Positives = 187/384 (48%), Gaps = 20/384 (5%)
Query: 44 AERSAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLR 103
A+++ A LYQ ++ +NI+ SP+ + L +V LG K Q + L ++
Sbjct: 23 AQKNTEFAVDLYQEVSLSHK-DNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETS 81
Query: 104 DEEVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINF 163
E L ++S + T+ L + LY + + ++ +K+ + ++F
Sbjct: 82 AGEEFFVLKSFFSAISEKK-QEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDF 140
Query: 164 RDKRSALQSINEWAAQTTDGKLPEVTKDVE--RTDGALLVNAMFFKPHWDEKFHHKMVDN 221
+D ++ + I+ W + TDGK+ ++ E +LVNA++FK W +KF +
Sbjct: 141 QDAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQL 200
Query: 222 RGFMVTRSYTVGVMMMH---RTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPL 278
F TV + MM RT Y Y+ + Q++E+ SLII++P +
Sbjct: 201 INFTKKNGSTVKIPMMKALLRTK-YGYFSESSLNYQVLELSYKGDEFSLIIILPAEGMDI 259
Query: 279 ERLEKLLTKEQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLS 338
E +EKL+T +Q+ W+ +MQ++ V ISLP+ VE D + L L +TE I DLS
Sbjct: 260 EEVEKLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKDVLYSLNITE-IFSGGCDLS 318
Query: 339 RMSGKKDLYLASVFHATAFELDTDGNPFDQDIYGREELRSPKL-------FYADHPFIFL 391
++ ++Y++ V FE++ DG+ + + P + F A+HPF+F+
Sbjct: 319 GITDSSEVYVSQVTQKVFFEINEDGS----EAATSTGIHIPVIMSLAQSQFIANHPFLFI 374
Query: 392 VRDTQSGSLLFIGRLVRPKGDKMR 415
++ + S+LF+GR+ P +++
Sbjct: 375 MKHNPTESILFMGRVTNPDTQEIK 398
>gi|219689110 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 2 [Homo sapiens]
Length = 415
Score = 147 bits (372), Expect = 1e-35
Identities = 106/407 (26%), Positives = 193/407 (47%), Gaps = 51/407 (12%)
Query: 51 AFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQL-------- 102
A +L++ +AK +N+ +SP ++S++ +V +G + +T Q VL ++
Sbjct: 12 ALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTPM 71
Query: 103 ---------------------------RDEEVHAGLGELLRSLSNSTARNVTWKLGSRLY 135
+++H+ L +++ ST N + ++L+
Sbjct: 72 TPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTG-NYLLESVNKLF 130
Query: 136 GPSSVSFADDFVRSSKQHYNCEHSKINFRD-KRSALQSINEWAAQTTDGKLPEVTKD--V 192
G S SF ++++R +++Y+ E ++F + A + IN W T GK+P + + V
Sbjct: 131 GEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSV 190
Query: 193 ERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRTGLYNYYDDEKEK 252
+ +LVNA++FK W F K+ F V + V MM+ N E K
Sbjct: 191 DGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLK 250
Query: 253 LQIVEMPLAHKLSSLIILMPHHVEP----LERLEKLLTKEQLKIWMGK--MQKKAVAISL 306
QI+E+P A +S + +L+P + LE LE +T ++L W K M + V + +
Sbjct: 251 AQILELPYAGDVS-MFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYI 309
Query: 307 PKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELDTDGNPF 366
P+ +E ++L+ L +G+ +A +K +A+ S MS + DL+L+ VFH +++ +G
Sbjct: 310 PQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEGTEA 369
Query: 367 DQD----IYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRP 409
+ GR P+ F ADHPF+FL+ + +LF GR P
Sbjct: 370 AAGTGGVMTGRTGHGGPQ-FVADHPFLFLIMHKITNCILFFGRFSSP 415
>gi|4505595 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 2 [Homo sapiens]
Length = 415
Score = 147 bits (372), Expect = 1e-35
Identities = 106/407 (26%), Positives = 193/407 (47%), Gaps = 51/407 (12%)
Query: 51 AFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQL-------- 102
A +L++ +AK +N+ +SP ++S++ +V +G + +T Q VL ++
Sbjct: 12 ALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTPM 71
Query: 103 ---------------------------RDEEVHAGLGELLRSLSNSTARNVTWKLGSRLY 135
+++H+ L +++ ST N + ++L+
Sbjct: 72 TPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTG-NYLLESVNKLF 130
Query: 136 GPSSVSFADDFVRSSKQHYNCEHSKINFRD-KRSALQSINEWAAQTTDGKLPEVTKD--V 192
G S SF ++++R +++Y+ E ++F + A + IN W T GK+P + + V
Sbjct: 131 GEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSV 190
Query: 193 ERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRTGLYNYYDDEKEK 252
+ +LVNA++FK W F K+ F V + V MM+ N E K
Sbjct: 191 DGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLK 250
Query: 253 LQIVEMPLAHKLSSLIILMPHHVEP----LERLEKLLTKEQLKIWMGK--MQKKAVAISL 306
QI+E+P A +S + +L+P + LE LE +T ++L W K M + V + +
Sbjct: 251 AQILELPYAGDVS-MFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYI 309
Query: 307 PKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELDTDGNPF 366
P+ +E ++L+ L +G+ +A +K +A+ S MS + DL+L+ VFH +++ +G
Sbjct: 310 PQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEGTEA 369
Query: 367 DQD----IYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRP 409
+ GR P+ F ADHPF+FL+ + +LF GR P
Sbjct: 370 AAGTGGVMTGRTGHGGPQ-FVADHPFLFLIMHKITNCILFFGRFSSP 415
>gi|170295807 neuroserpin precursor [Homo sapiens]
Length = 410
Score = 147 bits (371), Expect = 2e-35
Identities = 92/378 (24%), Positives = 194/378 (51%), Gaps = 15/378 (3%)
Query: 45 ERSAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRD 104
E A L+ ++Y + ENIL SP+ +A ++G++ LG + +T + + + + L++
Sbjct: 24 EAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKN 83
Query: 105 EEVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFR 164
E + L E ++ ++ V K+ + L+ + ++F++ K+++N + ++F
Sbjct: 84 GEEFSFLKEFSNMVTAKESQYVM-KIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFS 142
Query: 165 DKRSALQSINEWAAQTTDGKLPEVT--KDVERTDGALLVNAMFFKPHWDEKFHHKMVDNR 222
+ IN+W T+ + ++ +D + L+NA++FK +W +F +
Sbjct: 143 QNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTF 202
Query: 223 GFMVTRSYTVGVMMMHRTGLYNY--YDDEKEKL----QIVEMPLAHKLSSLIILMPHHVE 276
F V + MM++ G + Y + D + Q++E+P S+++++
Sbjct: 203 SFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEV 262
Query: 277 PLERLEKLLTKEQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKAD 336
PL LE L+ + ++ W ++K+ V + LP+ VE DL+ L LG+TE K+ A+
Sbjct: 263 PLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKD-AN 321
Query: 337 LSRMSGKKDLYLASVFHATAFELDTDGNPFDQDIYGREELRSPKLFY----ADHPFIFLV 392
L+ +S K+++L+ H + E++ +G+ + G + + Y DHPF FL+
Sbjct: 322 LTGLSDNKEIFLSKAIHKSFLEVNEEGSE-AAAVSGMIAISRMAVLYPQVIVDHPFFFLI 380
Query: 393 RDTQSGSLLFIGRLVRPK 410
R+ ++G++LF+GR++ P+
Sbjct: 381 RNRRTGTILFMGRVMHPE 398
>gi|4826904 neuroserpin precursor [Homo sapiens]
Length = 410
Score = 147 bits (371), Expect = 2e-35
Identities = 92/378 (24%), Positives = 194/378 (51%), Gaps = 15/378 (3%)
Query: 45 ERSAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRD 104
E A L+ ++Y + ENIL SP+ +A ++G++ LG + +T + + + + L++
Sbjct: 24 EAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKN 83
Query: 105 EEVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFR 164
E + L E ++ ++ V K+ + L+ + ++F++ K+++N + ++F
Sbjct: 84 GEEFSFLKEFSNMVTAKESQYVM-KIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFS 142
Query: 165 DKRSALQSINEWAAQTTDGKLPEVT--KDVERTDGALLVNAMFFKPHWDEKFHHKMVDNR 222
+ IN+W T+ + ++ +D + L+NA++FK +W +F +
Sbjct: 143 QNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTF 202
Query: 223 GFMVTRSYTVGVMMMHRTGLYNY--YDDEKEKL----QIVEMPLAHKLSSLIILMPHHVE 276
F V + MM++ G + Y + D + Q++E+P S+++++
Sbjct: 203 SFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEV 262
Query: 277 PLERLEKLLTKEQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKAD 336
PL LE L+ + ++ W ++K+ V + LP+ VE DL+ L LG+TE K+ A+
Sbjct: 263 PLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKD-AN 321
Query: 337 LSRMSGKKDLYLASVFHATAFELDTDGNPFDQDIYGREELRSPKLFY----ADHPFIFLV 392
L+ +S K+++L+ H + E++ +G+ + G + + Y DHPF FL+
Sbjct: 322 LTGLSDNKEIFLSKAIHKSFLEVNEEGSE-AAAVSGMIAISRMAVLYPQVIVDHPFFFLI 380
Query: 393 RDTQSGSLLFIGRLVRPK 410
R+ ++G++LF+GR++ P+
Sbjct: 381 RNRRTGTILFMGRVMHPE 398
>gi|27777657 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 12 [Homo
sapiens]
Length = 414
Score = 146 bits (368), Expect = 4e-35
Identities = 95/408 (23%), Positives = 207/408 (50%), Gaps = 8/408 (1%)
Query: 5 LLLSAFCLLEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAKDQAV 64
+LL+ LL+ + + K A + G ++++ K LA ++ L F L + +A
Sbjct: 13 VLLTVKGLLKPSFSPRNYK-ALSEVQGWKQRMAAKE--LARQNMDLGFKLLKKLAFYNPG 69
Query: 65 ENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSNSTAR 124
NI +SP+ ++++ ++ LG + +T + K + ++ ++++H G ++ L+ T +
Sbjct: 70 RNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFRKMPEKDLHEGFHYIIHELTQKT-Q 128
Query: 125 NVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQTTDGK 184
++ +G+ L+ + F+ +K Y+ E NF++ A + IN++ +Q T GK
Sbjct: 129 DLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLEMAQKQINDFISQKTHGK 188
Query: 185 LPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRTGLYN 244
+ + ++++ LL N +FF+ W +F + F + ++ +V V MM R+G+Y
Sbjct: 189 INNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLEKNSSVKVPMMFRSGIYQ 248
Query: 245 YYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQKKAVAI 304
D+K I+E+P ++++ IL L+ LEK L + W + ++ V +
Sbjct: 249 VGYDDKLSCTILEIPYQKNITAIFILPDE--GKLKHLEKGLQVDTFSRWKTLLSRRVVDV 306
Query: 305 SLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELDTDGN 364
S+P+ + T DL+K L+ +G+++ +++ DL++++ + L + H ++D G
Sbjct: 307 SVPRLHMTGTFDLKKTLSYIGVSKIFEEH-GDLTKIAPHRSLKVGEAVHKAELKMDERGT 365
Query: 365 PFDQDIYGRE-ELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRPKG 411
+ + +P + D P++ L+ + S+LF+G++V P G
Sbjct: 366 EGAAGTGAQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNPIG 413
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,280,977
Number of Sequences: 37866
Number of extensions: 581764
Number of successful extensions: 1992
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1730
Number of HSP's gapped (non-prelim): 66
length of query: 418
length of database: 18,247,518
effective HSP length: 105
effective length of query: 313
effective length of database: 14,271,588
effective search space: 4467007044
effective search space used: 4467007044
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.