Search of human proteins with 32189369

Search of human proteins with 32189369

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|32189369 DNA-directed DNA polymerase epsilon 2 [Homo
sapiens]
         (527 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32189369 DNA-directed DNA polymerase epsilon 2 [Homo sapiens]     1073   0.0  
gi|20127448 DNA-directed DNA polymerase alpha 2 [Homo sapiens]         43   8e-04
gi|110611228 utrophin [Homo sapiens]                                   32   1.9  
gi|14150108 EF-hand calcium binding domain 2 isoform a [Homo sap...    30   5.4  
gi|4503693 fibroblast growth factor 17 precursor [Homo sapiens]        30   7.1  

>gi|32189369 DNA-directed DNA polymerase epsilon 2 [Homo sapiens]
          Length = 527

 Score = 1073 bits (2774), Expect = 0.0
 Identities = 527/527 (100%), Positives = 527/527 (100%)

Query: 1   MAPERLRSRALSAFKLRGLLLRGEAIKYLTEALQSISELELEDKLEKIINAVEKQPLSSN 60
           MAPERLRSRALSAFKLRGLLLRGEAIKYLTEALQSISELELEDKLEKIINAVEKQPLSSN
Sbjct: 1   MAPERLRSRALSAFKLRGLLLRGEAIKYLTEALQSISELELEDKLEKIINAVEKQPLSSN 60

Query: 61  MIERSVVEAAVQECSQSVDETIEHVFNIIGAFDIPRFVYNSERKKFLPLLMTNHPAPNLF 120
           MIERSVVEAAVQECSQSVDETIEHVFNIIGAFDIPRFVYNSERKKFLPLLMTNHPAPNLF
Sbjct: 61  MIERSVVEAAVQECSQSVDETIEHVFNIIGAFDIPRFVYNSERKKFLPLLMTNHPAPNLF 120

Query: 121 GTPRDKAEMFRERYTILHQRTHRHELFTPPVIGSHPDESGSKFQLKTIETLLGSTTKIGD 180
           GTPRDKAEMFRERYTILHQRTHRHELFTPPVIGSHPDESGSKFQLKTIETLLGSTTKIGD
Sbjct: 121 GTPRDKAEMFRERYTILHQRTHRHELFTPPVIGSHPDESGSKFQLKTIETLLGSTTKIGD 180

Query: 181 AIVLGMITQLKEGKFFLEDPTGTVQLDLSKAQFHSGLYTEACFVLAEGWFEDQVFHVNAF 240
           AIVLGMITQLKEGKFFLEDPTGTVQLDLSKAQFHSGLYTEACFVLAEGWFEDQVFHVNAF
Sbjct: 181 AIVLGMITQLKEGKFFLEDPTGTVQLDLSKAQFHSGLYTEACFVLAEGWFEDQVFHVNAF 240

Query: 241 GFPPTEPSSTTRAYYGNINFFGGPSNTSVKTSAKLKQLEEENKDAMFVFLSDVWLDQVEV 300
           GFPPTEPSSTTRAYYGNINFFGGPSNTSVKTSAKLKQLEEENKDAMFVFLSDVWLDQVEV
Sbjct: 241 GFPPTEPSSTTRAYYGNINFFGGPSNTSVKTSAKLKQLEEENKDAMFVFLSDVWLDQVEV 300

Query: 301 LEKLRIMFAGYSPAPPTCFILCGNFSSAPYGKNQVQALKDSLKTLADIICEYPDIHQSSR 360
           LEKLRIMFAGYSPAPPTCFILCGNFSSAPYGKNQVQALKDSLKTLADIICEYPDIHQSSR
Sbjct: 301 LEKLRIMFAGYSPAPPTCFILCGNFSSAPYGKNQVQALKDSLKTLADIICEYPDIHQSSR 360

Query: 361 FVFVPGPEDPGFGSILPRPPLAESITNEFRQRVPFSVFTTNPCRIQYCTQEITVFREDLV 420
           FVFVPGPEDPGFGSILPRPPLAESITNEFRQRVPFSVFTTNPCRIQYCTQEITVFREDLV
Sbjct: 361 FVFVPGPEDPGFGSILPRPPLAESITNEFRQRVPFSVFTTNPCRIQYCTQEITVFREDLV 420

Query: 421 NKMCRNCVRFPSSNLAIPNHFVKTILSQGHLTPLPLYVCPVYWAYDYALRVYPVPDLLVI 480
           NKMCRNCVRFPSSNLAIPNHFVKTILSQGHLTPLPLYVCPVYWAYDYALRVYPVPDLLVI
Sbjct: 421 NKMCRNCVRFPSSNLAIPNHFVKTILSQGHLTPLPLYVCPVYWAYDYALRVYPVPDLLVI 480

Query: 481 ADKYDPFTTTNTECLCINPGSFPRSGFSFKVFYPSNKTVEDSKLQGF 527
           ADKYDPFTTTNTECLCINPGSFPRSGFSFKVFYPSNKTVEDSKLQGF
Sbjct: 481 ADKYDPFTTTNTECLCINPGSFPRSGFSFKVFYPSNKTVEDSKLQGF 527


>gi|20127448 DNA-directed DNA polymerase alpha 2 [Homo sapiens]
          Length = 598

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 42/173 (24%), Positives = 71/173 (41%), Gaps = 9/173 (5%)

Query: 359 SRFVFVPGPEDPGFGSILPRPPLAES-ITNEFRQRVPFSVFTTNPCRIQYCTQEITVFRE 417
           S  VFVP   D     + P+PP + S ++ E +++V F    + PC +        +   
Sbjct: 418 SHLVFVPSLRDVHHEPVYPQPPFSYSDLSREDKKQVQF---VSEPCSLSINGVIFGLTST 474

Query: 418 DLVNKMCRNCVRFPSSNLAIPNHFVKTILSQGHLTPL--PLYVCPVYWAYDYALRVYPV- 474
           DL+  +    +   S      +  +K IL+Q    PL  P     + +   Y     PV 
Sbjct: 475 DLLFHLGAEEISSSSGTSDRFSRILKHILTQRSYYPLYPPQEDMAIDYESFYVYAQLPVT 534

Query: 475 PDLLVIADKYDPFTTTNTECLCINPGSFPRS--GFSFKVFYPSNKTVEDSKLQ 525
           PD+L+I  +   F      C+C+NPG   +   G +F   Y      + ++ Q
Sbjct: 535 PDVLIIPSELRYFVKDVLGCVCVNPGRLTKGQVGGTFARLYLRRPAADGAERQ 587


>gi|110611228 utrophin [Homo sapiens]
          Length = 3433

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 21/62 (33%), Positives = 35/62 (56%), Gaps = 3/62 (4%)

Query: 33   LQSISELELEDKLEKIINAVEKQPLSSNMIER-SVVEAAVQECSQSVDETIEHVFNIIGA 91
            LQS +EL  E++ +KI  A+ KQ  SS + E+   + A      + VD+ +E + ++ GA
Sbjct: 2642 LQSKTELTPEERAQKIAKAMRKQ--SSEVKEKWESLNAVTSNWQKQVDKALEKLRDLQGA 2699

Query: 92   FD 93
             D
Sbjct: 2700 MD 2701


>gi|14150108 EF-hand calcium binding domain 2 isoform a [Homo
           sapiens]
          Length = 162

 Score = 30.0 bits (66), Expect = 5.4
 Identities = 14/34 (41%), Positives = 21/34 (61%)

Query: 17  RGLLLRGEAIKYLTEALQSISELELEDKLEKIIN 50
           RG L + E IKY+TE  +  S+ E+E+ L   I+
Sbjct: 109 RGFLTKDELIKYMTEEGEPFSQEEMEEMLSAAID 142


>gi|4503693 fibroblast growth factor 17 precursor [Homo sapiens]
          Length = 216

 Score = 29.6 bits (65), Expect = 7.1
 Identities = 35/126 (27%), Positives = 49/126 (38%), Gaps = 10/126 (7%)

Query: 113 NHPAPNLFGTPRDKAEMFRE-------RYTILHQRTHRHELFTPPVIGSHPDESGSKFQL 165
           NHP+PN     RD+  M  +        Y +  + + +H   T   I S   E G+KF  
Sbjct: 27  NHPSPNFNQYVRDQGAMTDQLSRRQIREYQLYSRTSGKHVQVTGRRI-SATAEDGNKFAK 85

Query: 166 KTIET-LLGSTTKIGDAIVLGMITQLKEGKFFLEDPTGTVQLDLSKAQFHSGLYTEACFV 224
             +ET   GS  +I  A     I   K GK  +  P+G  +  +         YT     
Sbjct: 86  LIVETDTFGSRVRIKGAESEKYICMNKRGK-LIGKPSGKSKDCVFTEIVLENNYTAFQNA 144

Query: 225 LAEGWF 230
             EGWF
Sbjct: 145 RHEGWF 150


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,273,670
Number of Sequences: 37866
Number of extensions: 992740
Number of successful extensions: 2156
Number of sequences better than 10.0: 5
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 2153
Number of HSP's gapped (non-prelim): 5
length of query: 527
length of database: 18,247,518
effective HSP length: 107
effective length of query: 420
effective length of database: 14,195,856
effective search space: 5962259520
effective search space used: 5962259520
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.