Guide to the Human Genome
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Search of human proteins with 31982953

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31982953 KTEL (Lys-Tyr-Glu-Leu) containing 1 [Homo sapiens]
         (392 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31982953 KTEL (Lys-Tyr-Glu-Leu) containing 1 [Homo sapiens]        830   0.0  
gi|176866369 KDEL (Lys-Asp-Glu-Leu) containing 1 [Homo sapiens]       160   2e-39
gi|153218487 KDEL (Lys-Asp-Glu-Leu) containing 2 [Homo sapiens]       134   2e-31
gi|56549696 E1A binding protein p400 [Homo sapiens]                    30   2.9  
gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H...    30   3.8  
gi|6005824 Sec23-interacting protein p125 [Homo sapiens]               30   3.8  
gi|22748643 chromatin modifying protein 4C [Homo sapiens]              29   8.4  

>gi|31982953 KTEL (Lys-Tyr-Glu-Leu) containing 1 [Homo sapiens]
          Length = 392

 Score =  830 bits (2144), Expect = 0.0
 Identities = 392/392 (100%), Positives = 392/392 (100%)

Query: 1   MEWWASSPLRLWLLLFLLPSAQGRQKESGSKWKVFIDQINRSLENYEPCSSQNCSCYHGV 60
           MEWWASSPLRLWLLLFLLPSAQGRQKESGSKWKVFIDQINRSLENYEPCSSQNCSCYHGV
Sbjct: 1   MEWWASSPLRLWLLLFLLPSAQGRQKESGSKWKVFIDQINRSLENYEPCSSQNCSCYHGV 60

Query: 61  IEEDLTPFRGGISRKMMAEVVRRKLGTHYQITKNRLYRENDCMFPSRCSGVEHFILEVIG 120
           IEEDLTPFRGGISRKMMAEVVRRKLGTHYQITKNRLYRENDCMFPSRCSGVEHFILEVIG
Sbjct: 61  IEEDLTPFRGGISRKMMAEVVRRKLGTHYQITKNRLYRENDCMFPSRCSGVEHFILEVIG 120

Query: 121 RLPDMEMVINVRDYPQVPKWMEPAIPVFSFSKTSEYHDIMYPAWTFWEGGPAVWPIYPTG 180
           RLPDMEMVINVRDYPQVPKWMEPAIPVFSFSKTSEYHDIMYPAWTFWEGGPAVWPIYPTG
Sbjct: 121 RLPDMEMVINVRDYPQVPKWMEPAIPVFSFSKTSEYHDIMYPAWTFWEGGPAVWPIYPTG 180

Query: 181 LGRWDLFREDLVRSAAQWPWKKKNSTAYFRGSRTSPERDPLILLSRKNPKLVDAEYTKNQ 240
           LGRWDLFREDLVRSAAQWPWKKKNSTAYFRGSRTSPERDPLILLSRKNPKLVDAEYTKNQ
Sbjct: 181 LGRWDLFREDLVRSAAQWPWKKKNSTAYFRGSRTSPERDPLILLSRKNPKLVDAEYTKNQ 240

Query: 241 AWKSMKDTLGKPAAKDVHLVDHCKYKYLFNFRGVAASFRFKHLFLCGSLVFHVGDEWLEF 300
           AWKSMKDTLGKPAAKDVHLVDHCKYKYLFNFRGVAASFRFKHLFLCGSLVFHVGDEWLEF
Sbjct: 241 AWKSMKDTLGKPAAKDVHLVDHCKYKYLFNFRGVAASFRFKHLFLCGSLVFHVGDEWLEF 300

Query: 301 FYPQLKPWVHYIPVKTDLSNVQELLQFVKANDDVAQEIAERGSQFIRNHLQMDDITCYWE 360
           FYPQLKPWVHYIPVKTDLSNVQELLQFVKANDDVAQEIAERGSQFIRNHLQMDDITCYWE
Sbjct: 301 FYPQLKPWVHYIPVKTDLSNVQELLQFVKANDDVAQEIAERGSQFIRNHLQMDDITCYWE 360

Query: 361 NLLSEYSKFLSYNVTRRKGYDQIIPKMLKTEL 392
           NLLSEYSKFLSYNVTRRKGYDQIIPKMLKTEL
Sbjct: 361 NLLSEYSKFLSYNVTRRKGYDQIIPKMLKTEL 392


>gi|176866369 KDEL (Lys-Asp-Glu-Leu) containing 1 [Homo sapiens]
          Length = 502

 Score =  160 bits (404), Expect = 2e-39
 Identities = 105/341 (30%), Positives = 177/341 (51%), Gaps = 16/341 (4%)

Query: 53  NCSCYHGVIEEDLTPFRGGISRKMMAEVVRR----KLGTHYQITKNRLYRENDCMFPSRC 108
           NC      I+ DL  F      K+  E+ +R    +   HY +  N++Y +         
Sbjct: 152 NCPETIAQIQRDLAHFPAVDPEKIAVEIPKRFGQRQSLCHYTLKDNKVYIKTHGEHVGFR 211

Query: 109 SGVEHFILEVIGR--LPDMEMVINVRDYPQVPKWMEPAI-PVFSFSKTSEYHDIMYPAWT 165
             ++  +L +  +  +PD+E+ +N+ D+P   K     I P+FS+  +++  DI+ P + 
Sbjct: 212 IFMDAILLSLTRKVKMPDVELFVNLGDWPLEKKKSNSNIHPIFSWCGSTDSKDIVMPTYD 271

Query: 166 FWEGGPAVWPIYPTGLGRWDLFREDLVRSAAQWPWKKKNSTAYFRGSRTSPERDPLILLS 225
             +       +  T +GR  L    +  +    PW+ KNSTA +RG  +  ER  L+ LS
Sbjct: 272 LTDS------VLET-MGRVSLDMMSVQANTGP-PWESKNSTAVWRGRDSRKERLELVKLS 323

Query: 226 RKNPKLVDAEYTKNQAWKSMKDTLGKPAAKDVHLVDHCKYKYLFNFRGVAASFRFKHLFL 285
           RK+P+L+DA +T    +K  ++  G P  K +   D  K+KY  N  G  A++R  +L +
Sbjct: 324 RKHPELIDAAFTNFFFFKHDENLYG-PIVKHISFFDFFKHKYQINIDGTVAAYRLPYLLV 382

Query: 286 CGSLVFHVGDEWLEFFYPQLKPWVHYIPVKTDLSNVQELLQFVKANDDVAQEIAERGSQF 345
             S+V      + E FY +L+PW HYIPVK++LS++ E L++ K +D+ A++IA+ G +F
Sbjct: 383 GDSVVLKQDSIYYEHFYNELQPWKHYIPVKSNLSDLLEKLKWAKDHDEEAKKIAKAGQEF 442

Query: 346 IRNHLQMDDITCYWENLLSEYSKFLSYNVTRRKGYDQIIPK 386
            RN+L  DDI CY+  L  EY+         R+G  ++ P+
Sbjct: 443 ARNNLMGDDIFCYYFKLFQEYANLQVSEPQIREGMKRVEPQ 483


>gi|153218487 KDEL (Lys-Asp-Glu-Leu) containing 2 [Homo sapiens]
          Length = 507

 Score =  134 bits (336), Expect = 2e-31
 Identities = 98/343 (28%), Positives = 166/343 (48%), Gaps = 24/343 (6%)

Query: 53  NCSCYHGVIEEDLTPFRGGISRKMMAEVVRR---KLGT--HYQITKNRLYRENDCMFPSR 107
           +C      I +D   F     ++M+ EV +R   + G   HY I  N +YR +   +   
Sbjct: 155 SCPTKEPQIAKDFASFPSINLQQMLKEVPKRFGDERGAIVHYTILNNHVYRRSLGKYTDF 214

Query: 108 CSGVEHFILEVIGR--LPDMEMVINVRDYPQVPKWMEPA---IPVFSFSKTSEYHDIMYP 162
               +  +L +  +  LPD+E  +N+ D+P   + +      IP+ S+  + +  D++ P
Sbjct: 215 KMFSDEILLSLTRKVLLPDLEFYVNLGDWPLEHRKVNGTPSPIPIISWCGSLDSRDVVLP 274

Query: 163 AWTFWEGGPAVWPIYPTGLGRWDLFREDL--VRSAAQWPWKKKNSTAYFRGSRTSPERDP 220
            +           I  + L        DL  ++      W  K   A+FRG  +  ER  
Sbjct: 275 TYD----------ITHSMLEAMRGVTNDLLSIQGNTGPSWINKTERAFFRGRDSREERLQ 324

Query: 221 LILLSRKNPKLVDAEYTKNQAWKSMKDTLGKPAAKDVHLVDHCKYKYLFNFRGVAASFRF 280
           L+ LS++NP+L+DA  T    ++  +  LGK  AK +   D  KYKY  N  G  A++R+
Sbjct: 325 LVQLSKENPQLLDAGITGYFFFQEKEKELGK--AKLMGFFDFFKYKYQVNVDGTVAAYRY 382

Query: 281 KHLFLCGSLVFHVGDEWLEFFYPQLKPWVHYIPVKTDLSNVQELLQFVKANDDVAQEIAE 340
            +L L  SLV      + E FY  L+PW HY+P+K +LS++ E +++ K ND+ A++IA+
Sbjct: 383 PYLMLGDSLVLKQDSPYYEHFYMALEPWKHYVPIKRNLSDLLEKVKWAKENDEEAKKIAK 442

Query: 341 RGSQFIRNHLQMDDITCYWENLLSEYSKFLSYNVTRRKGYDQI 383
            G    R+ LQ   + CY+  +L +Y++  S     R G + +
Sbjct: 443 EGQLMARDLLQPHRLYCYYYQVLQKYAERQSSKPEVRDGMELV 485


>gi|56549696 E1A binding protein p400 [Homo sapiens]
          Length = 3122

 Score = 30.4 bits (67), Expect = 2.9
 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 10/67 (14%)

Query: 195  AAQWPWKKKNSTAYFRGSRTSPERD----PLILLSRKNPKLVDAEYTKNQAWKSMKDTLG 250
            ++QWP  K +      G  TS E D    P    SRK+  L+D+ +  +Q   + +  +G
Sbjct: 960  SSQWPRPKPD------GEDTSGEEDADDCPGDRESRKDLVLIDSLFIMDQFKAAERMNIG 1013

Query: 251  KPAAKDV 257
            KP AKD+
Sbjct: 1014 KPNAKDI 1020


>gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo
            sapiens]
          Length = 4515

 Score = 30.0 bits (66), Expect = 3.8
 Identities = 44/190 (23%), Positives = 73/190 (38%), Gaps = 15/190 (7%)

Query: 185  DLFREDLVRSAAQWPWKKKNSTAYFRGSRTSPERDPLILLSRKNPKLVDAEYTKNQAWKS 244
            D F +  V S      K K     F+  + SP+     +   K P L + +   ++  KS
Sbjct: 3539 DWFHQVFVSSVVS---KSKEQEHSFKREKVSPKEVHEFISISKEPNLENEKNLLDKHIKS 3595

Query: 245  MKDTLGKPAAKDVHLVDHCKYKYLFNFR--GVAASFRFKHLFLCGSLVFHVGDEWLEFFY 302
              D L K   K V      + K  F+FR   V          +   + F   +EW  F Y
Sbjct: 3596 AIDMLTKSIFKVVSSALFNEDKLCFSFRLCTVIMQNNANGNLIQDDIGFLPEEEWNIFLY 3655

Query: 303  PQLKPWVHYIPVKTDLSNVQELLQFVKANDDVAQEIAE---RGSQFIRNHLQMDDITCYW 359
              +      I +K+ LS  +    F        Q +++   R  Q++  HL+   + C  
Sbjct: 3656 SGI-----LINIKSALSQSRLTSTFEIGESQHLQWLSDSRWRQCQYVSTHLEPFSLLC-- 3708

Query: 360  ENLLSEYSKF 369
            ++LLS  S++
Sbjct: 3709 KSLLSNVSQW 3718


>gi|6005824 Sec23-interacting protein p125 [Homo sapiens]
          Length = 1000

 Score = 30.0 bits (66), Expect = 3.8
 Identities = 29/110 (26%), Positives = 48/110 (43%), Gaps = 17/110 (15%)

Query: 142 EPAIPVFSFSKTSEYHDIMYPAWTF-----WEGGPAVWP-----IYPTGLGRWDLFREDL 191
           EP  P + + K  EY  +  P   F      E   +V P     +  T  GR+D++  D 
Sbjct: 267 EPVQPHWFYCKEVEYKQLWMPFSVFDSLNLEEIYNSVQPDPESVVLGTDGGRYDVYLYDR 326

Query: 192 VRSAAQW---PWKKKNSTAYFRGSRTSPERDPLILLSRKNPKLVDAEYTK 238
           +R AA W   P + +  T +++G   S      I  + +  + ++AEY K
Sbjct: 327 IRKAAYWEEEPAEVRRCTWFYKGDTDS----RFIPYTEEFSEKLEAEYKK 372


>gi|22748643 chromatin modifying protein 4C [Homo sapiens]
          Length = 233

 Score = 28.9 bits (63), Expect = 8.4
 Identities = 12/28 (42%), Positives = 19/28 (67%)

Query: 317 DLSNVQELLQFVKANDDVAQEIAERGSQ 344
           DL+ + +L+Q +    D+AQEI+E  SQ
Sbjct: 124 DLNKIDDLMQEITEQQDIAQEISEAFSQ 151


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.450 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,605,258
Number of Sequences: 37866
Number of extensions: 689494
Number of successful extensions: 1317
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1308
Number of HSP's gapped (non-prelim): 8
length of query: 392
length of database: 18,247,518
effective HSP length: 104
effective length of query: 288
effective length of database: 14,309,454
effective search space: 4121122752
effective search space used: 4121122752
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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