Search of human proteins with 31415882

Search of human proteins with 31415882

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31415882 exosome component 8 [Homo sapiens]
         (276 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31415882 exosome component 8 [Homo sapiens]                        556   e-159
gi|77812672 exosome component 9 isoform 1 [Homo sapiens]              120   1e-27
gi|77812670 exosome component 9 isoform 2 [Homo sapiens]              120   1e-27
gi|189083688 exosome component 7 [Homo sapiens]                       112   4e-25
gi|9506689 exosome component 4 [Homo sapiens]                          36   0.042
gi|188528628 polyribonucleotide nucleotidyltransferase 1 [Homo s...    35   0.071
gi|112789562 interferon, gamma-inducible protein 16 [Homo sapiens]     32   0.79 
gi|119392094 immunoglobulin mu binding protein 2 [Homo sapiens]        29   5.1  
gi|156119605 general transcription factor IIIC 4 [Homo sapiens]        29   5.1  
gi|17402904 homolog of yeast mRNA transport regulator 3 [Homo sa...    29   5.1  

>gi|31415882 exosome component 8 [Homo sapiens]
          Length = 276

 Score =  556 bits (1432), Expect = e-159
 Identities = 276/276 (100%), Positives = 276/276 (100%)

Query: 1   MAAGFKTVEPLEYYRRFLKENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVIC 60
           MAAGFKTVEPLEYYRRFLKENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVIC
Sbjct: 1   MAAGFKTVEPLEYYRRFLKENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVIC 60

Query: 61  GVKAEFAAPSTDAPDKGYVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQ 120
           GVKAEFAAPSTDAPDKGYVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQ
Sbjct: 61  GVKAEFAAPSTDAPDKGYVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQ 120

Query: 121 KEDLCISPGKLVWVLYCDLICLDYDGNILDACTFALLAALKNVQLPEVTINEETALAEVN 180
           KEDLCISPGKLVWVLYCDLICLDYDGNILDACTFALLAALKNVQLPEVTINEETALAEVN
Sbjct: 121 KEDLCISPGKLVWVLYCDLICLDYDGNILDACTFALLAALKNVQLPEVTINEETALAEVN 180

Query: 181 LKKKSYLNIRTHPVATSFAVFDDTLLIVDPTGEEEHLATGTLTIVMDEEGKLCCLHKPGG 240
           LKKKSYLNIRTHPVATSFAVFDDTLLIVDPTGEEEHLATGTLTIVMDEEGKLCCLHKPGG
Sbjct: 181 LKKKSYLNIRTHPVATSFAVFDDTLLIVDPTGEEEHLATGTLTIVMDEEGKLCCLHKPGG 240

Query: 241 SGLTGAKLQDCMSRAVTRHKEVKKLMDEVIKSMKPK 276
           SGLTGAKLQDCMSRAVTRHKEVKKLMDEVIKSMKPK
Sbjct: 241 SGLTGAKLQDCMSRAVTRHKEVKKLMDEVIKSMKPK 276


>gi|77812672 exosome component 9 isoform 1 [Homo sapiens]
          Length = 456

 Score =  120 bits (302), Expect = 1e-27
 Identities = 74/259 (28%), Positives = 132/259 (50%), Gaps = 5/259 (1%)

Query: 16  RFLKENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVICGVKAEFAAPSTDAPD 75
           R ++E  R DGR+  ++R   ++ G   T  G  +V+LG T V+  V  E  +P  +   
Sbjct: 16  RAIEEKKRLDGRQTYDYRNIRISFG---TDYGCCIVELGKTRVLGQVSCELVSPKLNRAT 72

Query: 76  KGYVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQKEDLCISPGKLVWVL 135
           +G +  N++L  + +  F  G   +     ++ +   + NS+ I  E LC+  G+ VW +
Sbjct: 73  EGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQI 132

Query: 136 YCDLICLDYDGNILDACTFALLAALKNVQLPEVTI-NEETALAEVNLKKKSYLNIRTHPV 194
             DL  L++DGNI+DA + A + AL + + P+V++  +E  L     +    L+I   P+
Sbjct: 133 RVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPI 192

Query: 195 ATSFAVFDD-TLLIVDPTGEEEHLATGTLTIVMDEEGKLCCLHKPGGSGLTGAKLQDCMS 253
             SFA F   T L+VDP   EE +  G L I M++  ++C +   GG  L   ++  C  
Sbjct: 193 CVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQVLRCSK 252

Query: 254 RAVTRHKEVKKLMDEVIKS 272
            A  +  E+ +L+ + +++
Sbjct: 253 IAGVKVAEITELILKALEN 271


>gi|77812670 exosome component 9 isoform 2 [Homo sapiens]
          Length = 439

 Score =  120 bits (302), Expect = 1e-27
 Identities = 74/259 (28%), Positives = 132/259 (50%), Gaps = 5/259 (1%)

Query: 16  RFLKENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVICGVKAEFAAPSTDAPD 75
           R ++E  R DGR+  ++R   ++ G   T  G  +V+LG T V+  V  E  +P  +   
Sbjct: 16  RAIEEKKRLDGRQTYDYRNIRISFG---TDYGCCIVELGKTRVLGQVSCELVSPKLNRAT 72

Query: 76  KGYVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQKEDLCISPGKLVWVL 135
           +G +  N++L  + +  F  G   +     ++ +   + NS+ I  E LC+  G+ VW +
Sbjct: 73  EGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQI 132

Query: 136 YCDLICLDYDGNILDACTFALLAALKNVQLPEVTI-NEETALAEVNLKKKSYLNIRTHPV 194
             DL  L++DGNI+DA + A + AL + + P+V++  +E  L     +    L+I   P+
Sbjct: 133 RVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPI 192

Query: 195 ATSFAVFDD-TLLIVDPTGEEEHLATGTLTIVMDEEGKLCCLHKPGGSGLTGAKLQDCMS 253
             SFA F   T L+VDP   EE +  G L I M++  ++C +   GG  L   ++  C  
Sbjct: 193 CVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQVLRCSK 252

Query: 254 RAVTRHKEVKKLMDEVIKS 272
            A  +  E+ +L+ + +++
Sbjct: 253 IAGVKVAEITELILKALEN 271


>gi|189083688 exosome component 7 [Homo sapiens]
          Length = 291

 Score =  112 bits (280), Expect = 4e-25
 Identities = 73/264 (27%), Positives = 125/264 (47%), Gaps = 10/264 (3%)

Query: 18  LKENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVICGVKAEFAAPSTDAPDKG 77
           ++E+ R DGR   ++R   V    +S   GSA VKLG+T ++ GVKAE   P  + P++G
Sbjct: 18  VQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAEMGTPKLEKPNEG 77

Query: 78  YVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQKEDLCISPGKLVWVLYC 137
           Y+   VD     +  F      +     +  +  +  N   +  + LCISP +  WVLY 
Sbjct: 78  YLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVLYV 137

Query: 138 DLICLDYDGNILDACTFALLAALKNVQLPEV-TINEETALAEVNLKKKSY----LNIRTH 192
           D++ L+  GN+ DA + A+ AAL N ++P V  + +E    ++ L    Y    L++   
Sbjct: 138 DVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSVENV 197

Query: 193 PVATSFAVFDDTLLIVDPTGEEEHLATGTLTIVMDEEGKLCCLHKPGGSGLTGAKLQDCM 252
           P   +         +VD T +EE  +  +L + +  +G + C+ K G   L    + + M
Sbjct: 198 PCIVTLCKI-GYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGSLDPESIFEMM 256

Query: 253 SRAVTRHKEVKKLMDEVIKSMKPK 276
                  K V K++   ++S+  K
Sbjct: 257 ETG----KRVGKVLHASLQSVVHK 276


>gi|9506689 exosome component 4 [Homo sapiens]
          Length = 245

 Score = 35.8 bits (81), Expect = 0.042
 Identities = 17/40 (42%), Positives = 22/40 (55%)

Query: 23 RPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVICGV 62
          R DGR  GE R     +G  + ADGSA ++ GNT  +  V
Sbjct: 13 RVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVV 52


>gi|188528628 polyribonucleotide nucleotidyltransferase 1 [Homo
           sapiens]
          Length = 783

 Score = 35.0 bits (79), Expect = 0.071
 Identities = 18/45 (40%), Positives = 23/45 (51%)

Query: 18  LKENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVICGV 62
           L E  R DGR+L   R  +  +    T  GSAL + G T V+C V
Sbjct: 353 LNEYKRCDGRDLTSLRNVSCEVDMFKTLHGSALFQRGQTQVLCTV 397


>gi|112789562 interferon, gamma-inducible protein 16 [Homo sapiens]
          Length = 729

 Score = 31.6 bits (70), Expect = 0.79
 Identities = 32/111 (28%), Positives = 50/111 (45%), Gaps = 18/111 (16%)

Query: 149 LDACTFALLA---ALKNVQLPEVTINEETALAEVNL----KKKSYLN----IRTHPVATS 197
           L+   F L+A   A +N+++P+  I   +   ++N      K S++N    +    V   
Sbjct: 586 LEVYPFTLVADVNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGE 645

Query: 198 FAVFDDTLLIVDPTGEEEHLATGTLTIVMDEEG---KLCCLHKPGGSGLTG 245
           F  ++    I D TG+ E +  G LT +  EEG   KL C      SG TG
Sbjct: 646 FTYYE----IQDNTGKMEVVVHGRLTTINCEEGDKLKLTCFELAPKSGNTG 692


>gi|119392094 immunoglobulin mu binding protein 2 [Homo sapiens]
          Length = 993

 Score = 28.9 bits (63), Expect = 5.1
 Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 7/61 (11%)

Query: 128 PGKLVWVLYCDLICLDYDGNILDA-CTFALLAALKNV------QLPEVTINEETALAEVN 180
           P KL+   Y D++ +D     L+A C   LL A K +      QLP  T++ + ALA ++
Sbjct: 360 PLKLLPESYFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGLS 419

Query: 181 L 181
           L
Sbjct: 420 L 420


>gi|156119605 general transcription factor IIIC 4 [Homo sapiens]
          Length = 822

 Score = 28.9 bits (63), Expect = 5.1
 Identities = 27/106 (25%), Positives = 45/106 (42%), Gaps = 12/106 (11%)

Query: 41  SISTADGSALVKLGNTTVICGVKAEFAAPSTDAPDKGYVVPNV------DLPPLCSSRFR 94
           S+     S L+K+G+ T +   K +FAA       + +++  V       LPP+   ++ 
Sbjct: 108 SVPAPLNSCLLKVGSKTEVAECKEKFAASKDPTVSQTFMLDRVFNPEGKALPPMRGFKYT 167

Query: 95  S-GPPGEEAQVASQFIADVIENSQIIQKEDLCISPGKLVWVLYCDL 139
           S  P G +A       A  ++N   IQ      +  +L WV   DL
Sbjct: 168 SWSPMGCDANGRCLLAALTMDNRLTIQ-----ANLNRLQWVQLVDL 208


>gi|17402904 homolog of yeast mRNA transport regulator 3 [Homo
           sapiens]
          Length = 272

 Score = 28.9 bits (63), Expect = 5.1
 Identities = 24/104 (23%), Positives = 40/104 (38%), Gaps = 13/104 (12%)

Query: 24  PDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVICGVKAEFAAPSTD----------- 72
           P  R+    R      G +S A GSA ++ G T V+C V     A   +           
Sbjct: 28  PGTRDPTRLRPVYARAGLLSQAKGSAYLEAGGTKVLCAVSGPRQAEGGERGGGPAGAGGE 87

Query: 73  --APDKGYVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIE 114
             A  +G ++ +    P    R R+ P G E +  +  + + +E
Sbjct: 88  APAALRGRLLCDFRRAPFAGRRRRAPPGGCEERELALALQEALE 131


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,079,652
Number of Sequences: 37866
Number of extensions: 490355
Number of successful extensions: 1094
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1083
Number of HSP's gapped (non-prelim): 11
length of query: 276
length of database: 18,247,518
effective HSP length: 101
effective length of query: 175
effective length of database: 14,423,052
effective search space: 2524034100
effective search space used: 2524034100
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.