BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|31083144 axin 1 isoform b [Homo sapiens] (826 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|31083144 axin 1 isoform b [Homo sapiens] 1698 0.0 gi|27501450 axin 1 isoform a [Homo sapiens] 1680 0.0 gi|195927059 axin 2 [Homo sapiens] 597 e-170 gi|19913392 regulator of G-protein signalling 3 isoform 4 [Homo ... 79 1e-14 gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo... 79 1e-14 gi|62865656 regulator of G-protein signalling 3 isoform 5 [Homo ... 79 1e-14 gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo ... 79 1e-14 gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo ... 79 1e-14 gi|4506505 regulator of G-protein signaling 10 isoform b [Homo s... 79 2e-14 gi|52694755 regulator of G-protein signaling 10 isoform a [Homo ... 79 2e-14 gi|4506519 regulator of G-protein signalling 5 [Homo sapiens] 75 2e-13 gi|18640750 regulator of G-protein signalling 18 [Homo sapiens] 74 4e-13 gi|115387108 regulator of G-protein signalling 1 [Homo sapiens] 74 6e-13 gi|85540441 regulator of G-protein signaling 21 [Homo sapiens] 74 7e-13 gi|16117777 regulator of G-protein signalling 8 isoform 1 [Homo ... 72 2e-12 gi|156416024 regulator of G-protein signalling 8 isoform 2 [Homo... 72 2e-12 gi|164664488 regulator of G-protein signaling 4 isoform 3 [Homo ... 69 2e-11 gi|5032039 regulator of G-protein signaling 4 isoform 2 [Homo sa... 69 2e-11 gi|156416012 regulator of G-protein signaling 4 isoform 1 [Homo ... 69 2e-11 gi|4506517 regulator of G-protein signaling 2, 24kDa [Homo sapiens] 68 3e-11 gi|21361405 regulator of G-protein signalling 17 [Homo sapiens] 63 1e-09 gi|21361304 regulator of G-protein signalling 14 [Homo sapiens] 63 1e-09 gi|13654235 regulator of G-protein signaling 20 isoform b [Homo ... 63 1e-09 gi|41281805 regulator of G-protein signaling 20 isoform a [Homo ... 63 1e-09 gi|156416009 regulator of G-protein signalling 16 [Homo sapiens] 63 1e-09 gi|86990435 G protein signalling regulator 19 [Homo sapiens] 62 2e-09 gi|5031705 G protein signalling regulator 19 [Homo sapiens] 62 2e-09 gi|4506511 regulator of G-protein signalling 13 [Homo sapiens] 60 8e-09 gi|21464139 regulator of G-protein signalling 13 [Homo sapiens] 60 8e-09 gi|4506509 regulator of G-protein signalling 12 isoform 2 [Homo ... 50 9e-06 >gi|31083144 axin 1 isoform b [Homo sapiens] Length = 826 Score = 1698 bits (4397), Expect = 0.0 Identities = 826/826 (100%), Positives = 826/826 (100%) Query: 1 MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTAT 60 MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTAT Sbjct: 1 MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTAT 60 Query: 61 PRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA 120 PRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA Sbjct: 61 PRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA 120 Query: 121 CTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA 180 CTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA Sbjct: 121 CTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA 180 Query: 181 MFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPT 240 MFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPT Sbjct: 181 MFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPT 240 Query: 241 LNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREP 300 LNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREP Sbjct: 241 LNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREP 300 Query: 301 VNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESV 360 VNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESV Sbjct: 301 VNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESV 360 Query: 361 QVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEE 420 QVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEE Sbjct: 361 QVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEE 420 Query: 421 EGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLR 480 EGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLR Sbjct: 421 EGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLR 480 Query: 481 TPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVH 540 TPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVH Sbjct: 481 TPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVH 540 Query: 541 HSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGV 600 HSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGV Sbjct: 541 HSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGV 600 Query: 601 ACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQ 660 ACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQ Sbjct: 601 ACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQ 660 Query: 661 PHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKR 720 PHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKR Sbjct: 661 PHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKR 720 Query: 721 ASRAPSKQRTRSQRKVGGGSAQPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTK 780 ASRAPSKQRTRSQRKVGGGSAQPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTK Sbjct: 721 ASRAPSKQRTRSQRKVGGGSAQPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTK 780 Query: 781 KGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD 826 KGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD Sbjct: 781 KGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD 826 >gi|27501450 axin 1 isoform a [Homo sapiens] Length = 862 Score = 1680 bits (4350), Expect = 0.0 Identities = 826/862 (95%), Positives = 826/862 (95%), Gaps = 36/862 (4%) Query: 1 MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTAT 60 MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTAT Sbjct: 1 MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTAT 60 Query: 61 PRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA 120 PRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA Sbjct: 61 PRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA 120 Query: 121 CTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA 180 CTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA Sbjct: 121 CTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA 180 Query: 181 MFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPT 240 MFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPT Sbjct: 181 MFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPT 240 Query: 241 LNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREP 300 LNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREP Sbjct: 241 LNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREP 300 Query: 301 VNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESV 360 VNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESV Sbjct: 301 VNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESV 360 Query: 361 QVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEE 420 QVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEE Sbjct: 361 QVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEE 420 Query: 421 EGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLR 480 EGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLR Sbjct: 421 EGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLR 480 Query: 481 TPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVH 540 TPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVH Sbjct: 481 TPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVH 540 Query: 541 HSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGV 600 HSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGV Sbjct: 541 HSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGV 600 Query: 601 ACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQ 660 ACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQ Sbjct: 601 ACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQ 660 Query: 661 PHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKR 720 PHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKR Sbjct: 661 PHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKR 720 Query: 721 ASRAPSKQR------------------------------------TRSQRKVGGGSAQPC 744 ASRAPSKQR TRSQRKVGGGSAQPC Sbjct: 721 ASRAPSKQRYVQEVMRRGRACVRPACAPVLHVVPAVSDMELSETETRSQRKVGGGSAQPC 780 Query: 745 DSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEV 804 DSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEV Sbjct: 781 DSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEV 840 Query: 805 REDEAVLPVFEEKIIGKVEKVD 826 REDEAVLPVFEEKIIGKVEKVD Sbjct: 841 REDEAVLPVFEEKIIGKVEKVD 862 >gi|195927059 axin 2 [Homo sapiens] Length = 843 Score = 597 bits (1539), Expect = e-170 Identities = 373/883 (42%), Positives = 503/883 (56%), Gaps = 118/883 (13%) Query: 11 DLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTATPRRSDLDLGY 70 D +SF EDAPRPPVPGEEGE P GKG K ++ RR++ LG Sbjct: 12 DPSSSFREDAPRPPVPGEEGETPPCQPGV-------GKGQVTKPMPVSSNTRRNEDGLG- 63 Query: 71 EPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPC 130 EPEG ASP P +W +SLHSLL DQDG LFRTFL++E C D LDFWFAC GFR++ Sbjct: 64 EPEGRASPDSPLTRWTKSLHSLLGDQDGAYLFRTFLEREKCVDTLDFWFACNGFRQMNLK 123 Query: 131 DSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQ 190 D+ K L++A+AIY++YI +NN IVS+Q KPATK++I+ I KQ ID MFDQAQTEIQ Sbjct: 124 DT---KTLRVAKAIYKRYI-ENNSIVSKQLKPATKTYIRDGIKKQQIDSIMFDQAQTEIQ 179 Query: 191 ATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPTLNEDEEWKCD 250 + MEEN Y FL SDIYLEY R+G E+ S+ G G+ K + GYLPTLNE+EEW C Sbjct: 180 SVMEENAYQMFLTSDIYLEYVRSGGENTAYMSN--GGLGSLKVVCGYLPTLNEEEEWTCA 237 Query: 251 QDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWR--EPVNPYYVNA 308 + P + L + R ++S R +E + Y S++ +PVNPY++ + Sbjct: 238 DFKCKLS----------PTVVGLSSKTLRATASVRSTETVDSGYRSFKRSDPVNPYHIGS 287 Query: 309 GYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRI--RKQHRREMQESVQVNGRV 366 GY APATSANDSE S + D++S+TDSSVDGIPPYR+ +KQ +REM SV+ NG+V Sbjct: 288 GYVFAPATSANDSEISSDALTDDSMSMTDSSVDGIPPYRVGSKKQLQREMHRSVKANGQV 347 Query: 367 PLPHIPRTYRVPKEVR-VEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDG 425 LPH PRT+R+PKE+ VEP FA ELI RLE ++ E+ LEERL+++R +EE E Sbjct: 348 SLPHFPRTHRLPKEMTPVEPATFAAELISRLEKLKLELESRHSLEERLQQIREDEEREGS 407 Query: 426 DPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLRTPGRQ 485 + + + AP H P + G ++EE+P++ILD+H+ RVL+TPG Q Sbjct: 408 ELT------LNSREGAPTQH--PLSLLPSG------SYEEDPQTILDDHLSRVLKTPGCQ 453 Query: 486 SPGPGH-----RSPDSGHV------------AKMPVALGGAASGHGKHVPKSGAKLDAAG 528 SPG G RSPD H K+P A + P G K Sbjct: 454 SPGVGRYSPRSRSPDHHHHHHSQYHSLLPPGGKLPPAAASPGA-----CPLLGGK-GFVT 507 Query: 529 LHHHRHVHHHV--HHSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAP 586 +HVHHH HH+ + KE++EAEAT+R G E + + ++ + +S++ P Sbjct: 508 KQTTKHVHHHYIHHHAVPKTKEEIEAEATQRVHCFCPGGSEYYCY-SKCKSHSKAPETMP 566 Query: 587 NASDGLAHSGKVGVACKRNAKKAESGKSASTEVPGAS----------EDAEKNQKIMQWI 636 + G + + KRN K E G + GA E+ +++Q + QW+ Sbjct: 567 SEQFGGSRGSTLP---KRNGKGTEPGLALPAREGGAPGGAGALQLPREEGDRSQDVWQWM 623 Query: 637 IEGEKEISRHRRTGHGSSGTRKPQPHENSRP-----LSLEHPWAGPQLRTSVQP-SHLFI 690 +E E++ + H + T+K P E++R S H W G P +HLF Sbjct: 624 LESERQ---SKPKPHSAQSTKKAYPLESARSSPGERASRHHLWGGNSGHPRTTPRAHLFT 680 Query: 691 QDPTMPPHPAPNPLTQLEEARRRLEEEEKRASR---APSKQRTRSQ-------------- 733 QDP MPP PN L QLEEA RRL E K + S+QR R+ Sbjct: 681 QDPAMPPLTPPNTLAQLEEACRRLAEVSKPPKQRCCVASQQRDRNHSATVQTGATPFSNP 740 Query: 734 ----------RKVGGGSAQPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGS 783 +K+ G A +VV Y+FCGE IPYR +++ +++TLG FKE L+KKG+ Sbjct: 741 SLAPEDHKEPKKLAGVHALQASELVVTYFFCGEEIPYRRMLKAQSLTLGHFKEQLSKKGN 800 Query: 784 YRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD 826 YRYYFKK SDEF CG VFEE+ EDE VLP++E +I+GKVE++D Sbjct: 801 YRYYFKKASDEFACGAVFEEIWEDETVLPMYEGRILGKVERID 843 >gi|19913392 regulator of G-protein signalling 3 isoform 4 [Homo sapiens] Length = 168 Score = 79.3 bits (194), Expect = 1e-14 Identities = 55/172 (31%), Positives = 83/172 (48%), Gaps = 29/172 (16%) Query: 62 RRSDLDLGYEPEGSAS-------PTPPY-LKWAESLHSLLDDQDGISLFRTFLKQEGCAD 113 RR + G P G A PT LKW ESL LL + G+++F+ FL+ E + Sbjct: 9 RRRNESPGAPPAGKADKMMKSFKPTSEEALKWGESLEKLLVHKYGLAVFQAFLRTEFSEE 68 Query: 114 LLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYI-------LDNNGIVSRQTKPATKS 166 L+FW AC F+K++ ++ K A+ I+ +YI ++ + TK +S Sbjct: 69 NLEFWLACEDFKKVK----SQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQS 124 Query: 167 FIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESP 218 +GC FD AQ I ME+++YP FL+SD+YL+ SP Sbjct: 125 VTRGC----------FDLAQKRIFGLMEKDSYPRFLRSDLYLDLINQKKMSP 166 >gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo sapiens] Length = 1198 Score = 79.3 bits (194), Expect = 1e-14 Identities = 55/172 (31%), Positives = 83/172 (48%), Gaps = 29/172 (16%) Query: 62 RRSDLDLGYEPEGSAS-------PTPPY-LKWAESLHSLLDDQDGISLFRTFLKQEGCAD 113 RR + G P G A PT LKW ESL LL + G+++F+ FL+ E + Sbjct: 1039 RRRNESPGAPPAGKADKMMKSFKPTSEEALKWGESLEKLLVHKYGLAVFQAFLRTEFSEE 1098 Query: 114 LLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYI-------LDNNGIVSRQTKPATKS 166 L+FW AC F+K++ ++ K A+ I+ +YI ++ + TK +S Sbjct: 1099 NLEFWLACEDFKKVK----SQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQS 1154 Query: 167 FIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESP 218 +GC FD AQ I ME+++YP FL+SD+YL+ SP Sbjct: 1155 VTRGC----------FDLAQKRIFGLMEKDSYPRFLRSDLYLDLINQKKMSP 1196 >gi|62865656 regulator of G-protein signalling 3 isoform 5 [Homo sapiens] Length = 311 Score = 79.3 bits (194), Expect = 1e-14 Identities = 55/172 (31%), Positives = 83/172 (48%), Gaps = 29/172 (16%) Query: 62 RRSDLDLGYEPEGSAS-------PTPPY-LKWAESLHSLLDDQDGISLFRTFLKQEGCAD 113 RR + G P G A PT LKW ESL LL + G+++F+ FL+ E + Sbjct: 152 RRRNESPGAPPAGKADKMMKSFKPTSEEALKWGESLEKLLVHKYGLAVFQAFLRTEFSEE 211 Query: 114 LLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYI-------LDNNGIVSRQTKPATKS 166 L+FW AC F+K++ ++ K A+ I+ +YI ++ + TK +S Sbjct: 212 NLEFWLACEDFKKVK----SQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQS 267 Query: 167 FIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESP 218 +GC FD AQ I ME+++YP FL+SD+YL+ SP Sbjct: 268 VTRGC----------FDLAQKRIFGLMEKDSYPRFLRSDLYLDLINQKKMSP 309 >gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo sapiens] Length = 519 Score = 79.3 bits (194), Expect = 1e-14 Identities = 55/172 (31%), Positives = 83/172 (48%), Gaps = 29/172 (16%) Query: 62 RRSDLDLGYEPEGSAS-------PTPPY-LKWAESLHSLLDDQDGISLFRTFLKQEGCAD 113 RR + G P G A PT LKW ESL LL + G+++F+ FL+ E + Sbjct: 360 RRRNESPGAPPAGKADKMMKSFKPTSEEALKWGESLEKLLVHKYGLAVFQAFLRTEFSEE 419 Query: 114 LLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYI-------LDNNGIVSRQTKPATKS 166 L+FW AC F+K++ ++ K A+ I+ +YI ++ + TK +S Sbjct: 420 NLEFWLACEDFKKVK----SQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQS 475 Query: 167 FIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESP 218 +GC FD AQ I ME+++YP FL+SD+YL+ SP Sbjct: 476 VTRGC----------FDLAQKRIFGLMEKDSYPRFLRSDLYLDLINQKKMSP 517 >gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo sapiens] Length = 917 Score = 79.3 bits (194), Expect = 1e-14 Identities = 55/172 (31%), Positives = 83/172 (48%), Gaps = 29/172 (16%) Query: 62 RRSDLDLGYEPEGSAS-------PTPPY-LKWAESLHSLLDDQDGISLFRTFLKQEGCAD 113 RR + G P G A PT LKW ESL LL + G+++F+ FL+ E + Sbjct: 758 RRRNESPGAPPAGKADKMMKSFKPTSEEALKWGESLEKLLVHKYGLAVFQAFLRTEFSEE 817 Query: 114 LLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYI-------LDNNGIVSRQTKPATKS 166 L+FW AC F+K++ ++ K A+ I+ +YI ++ + TK +S Sbjct: 818 NLEFWLACEDFKKVK----SQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQS 873 Query: 167 FIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESP 218 +GC FD AQ I ME+++YP FL+SD+YL+ SP Sbjct: 874 VTRGC----------FDLAQKRIFGLMEKDSYPRFLRSDLYLDLINQKKMSP 915 >gi|4506505 regulator of G-protein signaling 10 isoform b [Homo sapiens] Length = 167 Score = 79.0 bits (193), Expect = 2e-14 Identities = 51/161 (31%), Positives = 88/161 (54%), Gaps = 12/161 (7%) Query: 70 YEPEGSASPTPPYLK----WAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFR 125 ++ +GS+S + LK WA SL +LL+D +G+ FR FLK+E + + FW AC F+ Sbjct: 5 HDSDGSSSSSHQSLKSTAKWAASLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEDFK 64 Query: 126 KLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQA 185 K++ +EK A+ IY ++ + S Q +S + I+++ P MF + Sbjct: 65 KMQDKTQMQEK----AKEIYMTFL---SSKASSQVNVEGQSRLNEKILEE-PHPLMFQKL 116 Query: 186 QTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSS 226 Q +I M+ ++Y FLKSD++L++ RT E + Q++ Sbjct: 117 QDQIFNLMKYDSYSRFLKSDLFLKHKRTEEEEEDLPDAQTA 157 >gi|52694755 regulator of G-protein signaling 10 isoform a [Homo sapiens] Length = 181 Score = 79.0 bits (193), Expect = 2e-14 Identities = 51/161 (31%), Positives = 88/161 (54%), Gaps = 12/161 (7%) Query: 70 YEPEGSASPTPPYLK----WAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFR 125 ++ +GS+S + LK WA SL +LL+D +G+ FR FLK+E + + FW AC F+ Sbjct: 19 HDSDGSSSSSHQSLKSTAKWAASLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEDFK 78 Query: 126 KLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQA 185 K++ +EK A+ IY ++ + S Q +S + I+++ P MF + Sbjct: 79 KMQDKTQMQEK----AKEIYMTFL---SSKASSQVNVEGQSRLNEKILEE-PHPLMFQKL 130 Query: 186 QTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSS 226 Q +I M+ ++Y FLKSD++L++ RT E + Q++ Sbjct: 131 QDQIFNLMKYDSYSRFLKSDLFLKHKRTEEEEEDLPDAQTA 171 >gi|4506519 regulator of G-protein signalling 5 [Homo sapiens] Length = 181 Score = 75.1 bits (183), Expect = 2e-13 Identities = 42/129 (32%), Positives = 71/129 (55%), Gaps = 11/129 (8%) Query: 83 LKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLAR 142 L+W +SL LL + G++ F++FLK E + L+FW AC ++K++ + K + A+ Sbjct: 59 LQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIK----SPAKMAEKAK 114 Query: 143 AIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAM--FDQAQTEIQATMEENTYPS 200 IY ++I + F K MK L++P++ FD AQ I A ME+++ P Sbjct: 115 QIYEEFIQ-----TEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPR 169 Query: 201 FLKSDIYLE 209 F++S+ Y E Sbjct: 170 FVRSEFYQE 178 >gi|18640750 regulator of G-protein signalling 18 [Homo sapiens] Length = 235 Score = 74.3 bits (181), Expect = 4e-13 Identities = 48/139 (34%), Positives = 70/139 (50%), Gaps = 13/139 (9%) Query: 83 LKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLAR 142 +KW ES LL +DG+ F FLK E + ++FW AC F+K + ++ LK A+ Sbjct: 81 VKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSK---GPQQIHLK-AK 136 Query: 143 AIYRKYILDNNGIVSRQTKPATKSF-IKGCIMKQLIDPAM--FDQAQTEIQATMEENTYP 199 AIY K+I + K F K I + P + FD AQ+ + ME+++Y Sbjct: 137 AIYEKFIQTD------APKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYT 190 Query: 200 SFLKSDIYLEYTRTGSESP 218 FLKSDIYL+ + P Sbjct: 191 RFLKSDIYLDLMEGRPQRP 209 >gi|115387108 regulator of G-protein signalling 1 [Homo sapiens] Length = 209 Score = 73.9 bits (180), Expect = 6e-13 Identities = 45/133 (33%), Positives = 71/133 (53%), Gaps = 22/133 (16%) Query: 83 LKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLE----PCDSNEEKRL 138 ++W++SL LL +Q G ++F +FLK E + ++FW AC ++K E PC + E Sbjct: 80 MQWSQSLEKLLANQTGQNVFGSFLKSEFSEENIEFWLACEDYKKTESDLLPCKAEE---- 135 Query: 139 KLARAIYRKYILDNNG---IVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEE 195 IY+ ++ + + +T+ +T IK P FD+AQ I ME+ Sbjct: 136 -----IYKAFVHSDAAKQINIDFRTRESTAKKIKA------PTPTCFDEAQKVIYTLMEK 184 Query: 196 NTYPSFLKSDIYL 208 ++YP FLKSDIYL Sbjct: 185 DSYPRFLKSDIYL 197 >gi|85540441 regulator of G-protein signaling 21 [Homo sapiens] Length = 152 Score = 73.6 bits (179), Expect = 7e-13 Identities = 45/134 (33%), Positives = 72/134 (53%), Gaps = 13/134 (9%) Query: 77 SPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEK 136 SPT + W+E++ +LL +Q G+ FR FLK E + ++FW AC F+K + N +K Sbjct: 10 SPTAETMTWSENMDTLLANQAGLDAFRIFLKSEFSEENVEFWLACEDFKKTK----NADK 65 Query: 137 RLKLARAIYRKYILDNNGIVSRQTKPATKSF-IKGCIMKQLIDPAM--FDQAQTEIQATM 193 A+ IY ++ I + K F + I K + +P + FD+AQ I M Sbjct: 66 IASKAKMIYSEF------IEADAPKEINIDFGTRDLISKNIAEPTLKCFDEAQKLIYCLM 119 Query: 194 EENTYPSFLKSDIY 207 ++++P FLKS+IY Sbjct: 120 AKDSFPRFLKSEIY 133 >gi|16117777 regulator of G-protein signalling 8 isoform 1 [Homo sapiens] Length = 198 Score = 72.0 bits (175), Expect = 2e-12 Identities = 43/131 (32%), Positives = 72/131 (54%), Gaps = 17/131 (12%) Query: 84 KWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARA 143 +WA+S LL + G++ FR FLK E + L+FW AC F+K + K + A Sbjct: 70 RWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTR----STAKLVSKAHR 125 Query: 144 IYRKYI---LDNNGIVSRQTKPATKSFIKGCIMKQLIDPAM--FDQAQTEIQATMEENTY 198 I+ +++ + QT+ AT+ K L +P++ FDQAQ ++ + ME+++Y Sbjct: 126 IFEEFVDVQAPREVNIDFQTREATR--------KNLQEPSLTCFDQAQGKVHSLMEKDSY 177 Query: 199 PSFLKSDIYLE 209 P FL+S +YL+ Sbjct: 178 PRFLRSKMYLD 188 >gi|156416024 regulator of G-protein signalling 8 isoform 2 [Homo sapiens] Length = 180 Score = 72.0 bits (175), Expect = 2e-12 Identities = 43/131 (32%), Positives = 72/131 (54%), Gaps = 17/131 (12%) Query: 84 KWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARA 143 +WA+S LL + G++ FR FLK E + L+FW AC F+K + K + A Sbjct: 52 RWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTR----STAKLVSKAHR 107 Query: 144 IYRKYI---LDNNGIVSRQTKPATKSFIKGCIMKQLIDPAM--FDQAQTEIQATMEENTY 198 I+ +++ + QT+ AT+ K L +P++ FDQAQ ++ + ME+++Y Sbjct: 108 IFEEFVDVQAPREVNIDFQTREATR--------KNLQEPSLTCFDQAQGKVHSLMEKDSY 159 Query: 199 PSFLKSDIYLE 209 P FL+S +YL+ Sbjct: 160 PRFLRSKMYLD 170 >gi|164664488 regulator of G-protein signaling 4 isoform 3 [Homo sapiens] Length = 187 Score = 68.6 bits (166), Expect = 2e-11 Identities = 41/134 (30%), Positives = 71/134 (52%), Gaps = 11/134 (8%) Query: 84 KWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARA 143 KWAESL +L+ + G++ F+ FLK E + +DFW +C ++K++ + K A+ Sbjct: 40 KWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIK----SPSKLSPKAKK 95 Query: 144 IYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAM--FDQAQTEIQATMEENTYPSF 201 IY ++I V + S + + +++P + FD+AQ +I ME+++Y F Sbjct: 96 IYNEFI-----SVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRF 150 Query: 202 LKSDIYLEYTRTGS 215 LKS YL+ S Sbjct: 151 LKSRFYLDLVNPSS 164 >gi|5032039 regulator of G-protein signaling 4 isoform 2 [Homo sapiens] Length = 205 Score = 68.6 bits (166), Expect = 2e-11 Identities = 41/134 (30%), Positives = 71/134 (52%), Gaps = 11/134 (8%) Query: 84 KWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARA 143 KWAESL +L+ + G++ F+ FLK E + +DFW +C ++K++ + K A+ Sbjct: 58 KWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIK----SPSKLSPKAKK 113 Query: 144 IYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAM--FDQAQTEIQATMEENTYPSF 201 IY ++I V + S + + +++P + FD+AQ +I ME+++Y F Sbjct: 114 IYNEFI-----SVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRF 168 Query: 202 LKSDIYLEYTRTGS 215 LKS YL+ S Sbjct: 169 LKSRFYLDLVNPSS 182 >gi|156416012 regulator of G-protein signaling 4 isoform 1 [Homo sapiens] Length = 302 Score = 68.6 bits (166), Expect = 2e-11 Identities = 41/134 (30%), Positives = 71/134 (52%), Gaps = 11/134 (8%) Query: 84 KWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARA 143 KWAESL +L+ + G++ F+ FLK E + +DFW +C ++K++ + K A+ Sbjct: 155 KWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIK----SPSKLSPKAKK 210 Query: 144 IYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAM--FDQAQTEIQATMEENTYPSF 201 IY ++I V + S + + +++P + FD+AQ +I ME+++Y F Sbjct: 211 IYNEFI-----SVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRF 265 Query: 202 LKSDIYLEYTRTGS 215 LKS YL+ S Sbjct: 266 LKSRFYLDLVNPSS 279 >gi|4506517 regulator of G-protein signaling 2, 24kDa [Homo sapiens] Length = 211 Score = 68.2 bits (165), Expect = 3e-11 Identities = 45/155 (29%), Positives = 73/155 (47%), Gaps = 14/155 (9%) Query: 57 STATPRRSDLDLGYEPEGSASPTPPYLK-WAESLHSLLDDQDGISLFRTFLKQEGCADLL 115 +++TP + + + P+P + W+E+ LL + G++ FR FLK E C + + Sbjct: 51 NSSTPGKPKTGKKSKQQAFIKPSPEEAQLWSEAFDELLASKYGLAAFRAFLKSEFCEENI 110 Query: 116 DFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQ 175 +FW AC F+K + + +K AR IY + I K F ++ Q Sbjct: 111 EFWLACEDFKKTK----SPQKLSSKARKIYTDF------IEKEAPKEINIDFQTKTLIAQ 160 Query: 176 LIDPA---MFDQAQTEIQATMEENTYPSFLKSDIY 207 I A F AQ + + ME N+YP FL+S+ Y Sbjct: 161 NIQEATSGCFTTAQKRVYSLMENNSYPRFLESEFY 195 >gi|21361405 regulator of G-protein signalling 17 [Homo sapiens] Length = 210 Score = 63.2 bits (152), Expect = 1e-09 Identities = 43/137 (31%), Positives = 70/137 (51%), Gaps = 11/137 (8%) Query: 83 LKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLAR 142 L W+++ ++ G +LFR FL+ E + L FW AC +K + EEK AR Sbjct: 79 LSWSQNFDKMMKAPAGRNLFREFLRTEYSEENLLFWLACEDLKKEQNKKVIEEK----AR 134 Query: 143 AIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLID--PAMFDQAQTEIQATMEENTYPS 200 IY YI I+S + + + S ++ I + L+D P M++ AQ +I M +++P Sbjct: 135 MIYEDYI----SILSPK-EVSLDSRVREVINRNLLDPNPHMYEDAQLQIYTLMHRDSFPR 189 Query: 201 FLKSDIYLEYTRTGSES 217 FL S IY + + + S Sbjct: 190 FLNSQIYKSFVESTAGS 206 >gi|21361304 regulator of G-protein signalling 14 [Homo sapiens] Length = 566 Score = 63.2 bits (152), Expect = 1e-09 Identities = 58/213 (27%), Positives = 95/213 (44%), Gaps = 26/213 (12%) Query: 25 VPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTATPRRSDLDLGYEPEGSASPTP---- 80 VP L +D +S + G+G G R S L + P G +SP P Sbjct: 10 VPNGRMVLAVSDGELSSTTGPQGQGEG----------RGSSLSIHSLPSGPSSPFPTEEQ 59 Query: 81 PYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKL 140 P WA S LL D G++ F FLK+E A+ + FW AC F+++ D+ ++ + Sbjct: 60 PVASWALSFERLLQDPLGLAYFTEFLKKEFSAENVTFWKACERFQQIPASDT--QQLAQE 117 Query: 141 ARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLI---DPAMFDQAQTEIQATMEENT 197 AR IY++++ S Q + + ++++ P MF Q +I M+ ++ Sbjct: 118 ARNIYQEFL-------SSQALSPVNIDRQAWLGEEVLAEPRPDMFRAQQLQIFNLMKFDS 170 Query: 198 YPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGT 230 Y F+KS +Y E +E + SS G+ Sbjct: 171 YARFVKSPLYRECLLAEAEGRPLREPGSSRLGS 203 >gi|13654235 regulator of G-protein signaling 20 isoform b [Homo sapiens] Length = 241 Score = 62.8 bits (151), Expect = 1e-09 Identities = 46/150 (30%), Positives = 75/150 (50%), Gaps = 14/150 (9%) Query: 72 PEGSASPTPPYLK---WAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLE 128 P SP P + WA+S L+ G + FR FL+ E + + FW AC +K Sbjct: 96 PTWEESPAPTLEEVNAWAQSFDKLMVTPAGRNAFREFLRTEFSEENMLFWMACEELKKEA 155 Query: 129 PCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA--MFDQAQ 186 + EEK AR IY YI I+S + + + S ++ I + +++P+ +FD AQ Sbjct: 156 NKNIIEEK----ARIIYEDYI----SILSPK-EVSLDSRVREVINRNMVEPSQHIFDDAQ 206 Query: 187 TEIQATMEENTYPSFLKSDIYLEYTRTGSE 216 +I M ++YP F+ S +Y + ++ SE Sbjct: 207 LQIYTLMHRDSYPRFMNSAVYKDLLQSLSE 236 >gi|41281805 regulator of G-protein signaling 20 isoform a [Homo sapiens] Length = 388 Score = 62.8 bits (151), Expect = 1e-09 Identities = 46/150 (30%), Positives = 75/150 (50%), Gaps = 14/150 (9%) Query: 72 PEGSASPTPPYLK---WAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLE 128 P SP P + WA+S L+ G + FR FL+ E + + FW AC +K Sbjct: 243 PTWEESPAPTLEEVNAWAQSFDKLMVTPAGRNAFREFLRTEFSEENMLFWMACEELKKEA 302 Query: 129 PCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA--MFDQAQ 186 + EEK AR IY YI I+S + + + S ++ I + +++P+ +FD AQ Sbjct: 303 NKNIIEEK----ARIIYEDYI----SILSPK-EVSLDSRVREVINRNMVEPSQHIFDDAQ 353 Query: 187 TEIQATMEENTYPSFLKSDIYLEYTRTGSE 216 +I M ++YP F+ S +Y + ++ SE Sbjct: 354 LQIYTLMHRDSYPRFMNSAVYKDLLQSLSE 383 >gi|156416009 regulator of G-protein signalling 16 [Homo sapiens] Length = 202 Score = 62.8 bits (151), Expect = 1e-09 Identities = 42/146 (28%), Positives = 65/146 (44%), Gaps = 13/146 (8%) Query: 83 LKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLAR 142 L W ES LL ++G++ F FLK E + L+FW AC F+K+ + K A Sbjct: 60 LGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIR----SATKLASRAH 115 Query: 143 AIYRKYILD---NNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYP 199 I+ ++I + +T T+ + Q FD AQ + + ME+++YP Sbjct: 116 QIFEEFICSEAPKEVNIDHETHELTRMNL------QTATATCFDAAQGKTRTLMEKDSYP 169 Query: 200 SFLKSDIYLEYTRTGSESPKVCSDQS 225 FLKS Y + S + S S Sbjct: 170 RFLKSPAYRDLAAQASAASATLSSCS 195 >gi|86990435 G protein signalling regulator 19 [Homo sapiens] Length = 217 Score = 62.0 bits (149), Expect = 2e-09 Identities = 56/197 (28%), Positives = 87/197 (44%), Gaps = 16/197 (8%) Query: 18 EDAPRPPVPGEEGELVSTDP--RPASYSFCSGKGVGIKGETSTA--TPRRSDLDLGYEPE 73 E+A RPP P P +C E A R S L E Sbjct: 15 EEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQASRESKLQPLPSCE 74 Query: 74 GSASPTPPYLK-WAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDS 132 A+P+P ++ WA+S L+ G S+FR FL+ E + + FW AC + ++ Sbjct: 75 VCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELK----AEA 130 Query: 133 NEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA--MFDQAQTEIQ 190 N+ + AR IY Y+ I+S + + + S ++ I K++ +P+ FD AQ +I Sbjct: 131 NQHVVDEKARLIYEDYV----SILSPK-EVSLDSRVREGINKKMQEPSAHTFDDAQLQIY 185 Query: 191 ATMEENTYPSFLKSDIY 207 M ++YP FL S Y Sbjct: 186 TLMHRDSYPRFLSSPTY 202 >gi|5031705 G protein signalling regulator 19 [Homo sapiens] Length = 217 Score = 62.0 bits (149), Expect = 2e-09 Identities = 56/197 (28%), Positives = 87/197 (44%), Gaps = 16/197 (8%) Query: 18 EDAPRPPVPGEEGELVSTDP--RPASYSFCSGKGVGIKGETSTA--TPRRSDLDLGYEPE 73 E+A RPP P P +C E A R S L E Sbjct: 15 EEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQASRESKLQPLPSCE 74 Query: 74 GSASPTPPYLK-WAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDS 132 A+P+P ++ WA+S L+ G S+FR FL+ E + + FW AC + ++ Sbjct: 75 VCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELK----AEA 130 Query: 133 NEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA--MFDQAQTEIQ 190 N+ + AR IY Y+ I+S + + + S ++ I K++ +P+ FD AQ +I Sbjct: 131 NQHVVDEKARLIYEDYV----SILSPK-EVSLDSRVREGINKKMQEPSAHTFDDAQLQIY 185 Query: 191 ATMEENTYPSFLKSDIY 207 M ++YP FL S Y Sbjct: 186 TLMHRDSYPRFLSSPTY 202 >gi|4506511 regulator of G-protein signalling 13 [Homo sapiens] Length = 159 Score = 60.1 bits (144), Expect = 8e-09 Identities = 35/133 (26%), Positives = 70/133 (52%), Gaps = 11/133 (8%) Query: 83 LKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLAR 142 L+WA+S +L+ + G ++ +LK E + + FW AC ++K+ ++ R+ A+ Sbjct: 29 LQWAQSFENLMATKYGPVVYAAYLKMEHSDENIQFWMACETYKKI----ASRWSRISRAK 84 Query: 143 AIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDP--AMFDQAQTEIQATMEENTYPS 200 +Y+ YI + + S + I++ + +P F++AQ + ME ++YP Sbjct: 85 KLYKIYIQPQS-----PREINIDSSTRETIIRNIQEPTETCFEEAQKIVYMHMERDSYPR 139 Query: 201 FLKSDIYLEYTRT 213 FLKS++Y + +T Sbjct: 140 FLKSEMYQKLLKT 152 >gi|21464139 regulator of G-protein signalling 13 [Homo sapiens] Length = 159 Score = 60.1 bits (144), Expect = 8e-09 Identities = 35/133 (26%), Positives = 70/133 (52%), Gaps = 11/133 (8%) Query: 83 LKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLAR 142 L+WA+S +L+ + G ++ +LK E + + FW AC ++K+ ++ R+ A+ Sbjct: 29 LQWAQSFENLMATKYGPVVYAAYLKMEHSDENIQFWMACETYKKI----ASRWSRISRAK 84 Query: 143 AIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDP--AMFDQAQTEIQATMEENTYPS 200 +Y+ YI + + S + I++ + +P F++AQ + ME ++YP Sbjct: 85 KLYKIYIQPQS-----PREINIDSSTRETIIRNIQEPTETCFEEAQKIVYMHMERDSYPR 139 Query: 201 FLKSDIYLEYTRT 213 FLKS++Y + +T Sbjct: 140 FLKSEMYQKLLKT 152 >gi|4506509 regulator of G-protein signalling 12 isoform 2 [Homo sapiens] Length = 1376 Score = 50.1 bits (118), Expect = 9e-06 Identities = 41/132 (31%), Positives = 57/132 (43%), Gaps = 20/132 (15%) Query: 85 WAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAI 144 WA S LL D G+ F FL++E + + FW AC F + D E AR I Sbjct: 712 WAVSFERLLQDPVGVRYFSDFLRKEFSEENILFWQACEYFNHVPAHDKKELS--YRAREI 769 Query: 145 YRKYILDNNGIVSRQTKPATKSFIKGCIMKQLID-------PAMFDQAQTEIQATMEENT 197 + K+ + S+ T P QL D P MF + Q +I M+ ++ Sbjct: 770 FSKF------LCSKATTPVNID-----SQAQLADDVLRAPHPDMFKEQQLQIFNLMKFDS 818 Query: 198 YPSFLKSDIYLE 209 Y FLKS +Y E Sbjct: 819 YTRFLKSPLYQE 830 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.132 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 38,500,497 Number of Sequences: 37866 Number of extensions: 2148627 Number of successful extensions: 11171 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 123 Number of HSP's successfully gapped in prelim test: 211 Number of HSP's that attempted gapping in prelim test: 9863 Number of HSP's gapped (non-prelim): 1016 length of query: 826 length of database: 18,247,518 effective HSP length: 111 effective length of query: 715 effective length of database: 14,044,392 effective search space: 10041740280 effective search space used: 10041740280 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.