Guide to the Human Genome
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Search of human proteins with 30410790

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|30410790 tumor suppressor candidate 3 isoform b [Homo
sapiens]
         (347 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|30410790 tumor suppressor candidate 3 isoform b [Homo sapiens]     704   0.0  
gi|30410788 tumor suppressor candidate 3 isoform a [Homo sapiens]     697   0.0  
gi|215983058 magnesium transporter 1 [Homo sapiens]                   491   e-139
gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ...    32   1.1  
gi|16933540 fibroblast activation protein, alpha subunit [Homo s...    30   4.2  
gi|38569407 arylsulfatase B isoform 2 precursor [Homo sapiens]         29   5.4  
gi|38569405 arylsulfatase B isoform 1 precursor [Homo sapiens]         29   5.4  
gi|31563526 solute carrier family 24 (sodium/potassium/calcium e...    29   5.4  

>gi|30410790 tumor suppressor candidate 3 isoform b [Homo sapiens]
          Length = 347

 Score =  704 bits (1818), Expect = 0.0
 Identities = 347/347 (100%), Positives = 347/347 (100%)

Query: 1   MGARGAPSRRRQAGRRLRYLPTGSFPFLLLLLLLCIQLGGGQKKKENLLAEKVEQLMEWS 60
           MGARGAPSRRRQAGRRLRYLPTGSFPFLLLLLLLCIQLGGGQKKKENLLAEKVEQLMEWS
Sbjct: 1   MGARGAPSRRRQAGRRLRYLPTGSFPFLLLLLLLCIQLGGGQKKKENLLAEKVEQLMEWS 60

Query: 61  SRRSIFRMNGDKFRKFIKAPPRNYSMIVMFTALQPQRQCSVCRQANEEYQILANSWRYSS 120
           SRRSIFRMNGDKFRKFIKAPPRNYSMIVMFTALQPQRQCSVCRQANEEYQILANSWRYSS
Sbjct: 61  SRRSIFRMNGDKFRKFIKAPPRNYSMIVMFTALQPQRQCSVCRQANEEYQILANSWRYSS 120

Query: 121 AFCNKLFFSMVDYDEGTDVFQQLNMNSAPTFMHFPPKGRPKRADTFDLQRIGFAAEQLAK 180
           AFCNKLFFSMVDYDEGTDVFQQLNMNSAPTFMHFPPKGRPKRADTFDLQRIGFAAEQLAK
Sbjct: 121 AFCNKLFFSMVDYDEGTDVFQQLNMNSAPTFMHFPPKGRPKRADTFDLQRIGFAAEQLAK 180

Query: 181 WIADRTDVHIRVFRPPNYSGTIALALLVSLVGGLLYLRRNNLEFIYNKTGWAMVSLCIVF 240
           WIADRTDVHIRVFRPPNYSGTIALALLVSLVGGLLYLRRNNLEFIYNKTGWAMVSLCIVF
Sbjct: 181 WIADRTDVHIRVFRPPNYSGTIALALLVSLVGGLLYLRRNNLEFIYNKTGWAMVSLCIVF 240

Query: 241 AMTSGQMWNHIRGPPYAHKNPHNGQVSYIHGSSQAQFVAESHIILVLNAAITMGMVLLNE 300
           AMTSGQMWNHIRGPPYAHKNPHNGQVSYIHGSSQAQFVAESHIILVLNAAITMGMVLLNE
Sbjct: 241 AMTSGQMWNHIRGPPYAHKNPHNGQVSYIHGSSQAQFVAESHIILVLNAAITMGMVLLNE 300

Query: 301 AATSKGDVGKRRIICLVGLGLVVFFFSFLLSIFRSKYHGYPYSFLIK 347
           AATSKGDVGKRRIICLVGLGLVVFFFSFLLSIFRSKYHGYPYSFLIK
Sbjct: 301 AATSKGDVGKRRIICLVGLGLVVFFFSFLLSIFRSKYHGYPYSFLIK 347


>gi|30410788 tumor suppressor candidate 3 isoform a [Homo sapiens]
          Length = 348

 Score =  697 bits (1800), Expect = 0.0
 Identities = 344/345 (99%), Positives = 344/345 (99%)

Query: 1   MGARGAPSRRRQAGRRLRYLPTGSFPFLLLLLLLCIQLGGGQKKKENLLAEKVEQLMEWS 60
           MGARGAPSRRRQAGRRLRYLPTGSFPFLLLLLLLCIQLGGGQKKKENLLAEKVEQLMEWS
Sbjct: 1   MGARGAPSRRRQAGRRLRYLPTGSFPFLLLLLLLCIQLGGGQKKKENLLAEKVEQLMEWS 60

Query: 61  SRRSIFRMNGDKFRKFIKAPPRNYSMIVMFTALQPQRQCSVCRQANEEYQILANSWRYSS 120
           SRRSIFRMNGDKFRKFIKAPPRNYSMIVMFTALQPQRQCSVCRQANEEYQILANSWRYSS
Sbjct: 61  SRRSIFRMNGDKFRKFIKAPPRNYSMIVMFTALQPQRQCSVCRQANEEYQILANSWRYSS 120

Query: 121 AFCNKLFFSMVDYDEGTDVFQQLNMNSAPTFMHFPPKGRPKRADTFDLQRIGFAAEQLAK 180
           AFCNKLFFSMVDYDEGTDVFQQLNMNSAPTFMHFPPKGRPKRADTFDLQRIGFAAEQLAK
Sbjct: 121 AFCNKLFFSMVDYDEGTDVFQQLNMNSAPTFMHFPPKGRPKRADTFDLQRIGFAAEQLAK 180

Query: 181 WIADRTDVHIRVFRPPNYSGTIALALLVSLVGGLLYLRRNNLEFIYNKTGWAMVSLCIVF 240
           WIADRTDVHIRVFRPPNYSGTIALALLVSLVGGLLYLRRNNLEFIYNKTGWAMVSLCIVF
Sbjct: 181 WIADRTDVHIRVFRPPNYSGTIALALLVSLVGGLLYLRRNNLEFIYNKTGWAMVSLCIVF 240

Query: 241 AMTSGQMWNHIRGPPYAHKNPHNGQVSYIHGSSQAQFVAESHIILVLNAAITMGMVLLNE 300
           AMTSGQMWNHIRGPPYAHKNPHNGQVSYIHGSSQAQFVAESHIILVLNAAITMGMVLLNE
Sbjct: 241 AMTSGQMWNHIRGPPYAHKNPHNGQVSYIHGSSQAQFVAESHIILVLNAAITMGMVLLNE 300

Query: 301 AATSKGDVGKRRIICLVGLGLVVFFFSFLLSIFRSKYHGYPYSFL 345
           AATSKGDVGKRRIICLVGLGLVVFFFSFLLSIFRSKYHGYPYS L
Sbjct: 301 AATSKGDVGKRRIICLVGLGLVVFFFSFLLSIFRSKYHGYPYSDL 345


>gi|215983058 magnesium transporter 1 [Homo sapiens]
          Length = 367

 Score =  491 bits (1263), Expect = e-139
 Identities = 224/324 (69%), Positives = 282/324 (87%), Gaps = 1/324 (0%)

Query: 24  SFPFLLLLLLLC-IQLGGGQKKKENLLAEKVEQLMEWSSRRSIFRMNGDKFRKFIKAPPR 82
           S   ++ LL++C +     Q+KKE +L+EKV QLMEW+++R + RMNGDKFR+ +KAPPR
Sbjct: 43  SVTMVVALLIVCDVPSASAQRKKEMVLSEKVSQLMEWTNKRPVIRMNGDKFRRLVKAPPR 102

Query: 83  NYSMIVMFTALQPQRQCSVCRQANEEYQILANSWRYSSAFCNKLFFSMVDYDEGTDVFQQ 142
           NYS+IVMFTALQ  RQC VC+QA+EE+QILANSWRYSSAF N++FF+MVD+DEG+DVFQ 
Sbjct: 103 NYSVIVMFTALQLHRQCVVCKQADEEFQILANSWRYSSAFTNRIFFAMVDFDEGSDVFQM 162

Query: 143 LNMNSAPTFMHFPPKGRPKRADTFDLQRIGFAAEQLAKWIADRTDVHIRVFRPPNYSGTI 202
           LNMNSAPTF++FP KG+PKR DT++LQ  GF+AEQ+A+WIADRTDV+IRV RPPNY+G +
Sbjct: 163 LNMNSAPTFINFPAKGKPKRGDTYELQVRGFSAEQIARWIADRTDVNIRVIRPPNYAGPL 222

Query: 203 ALALLVSLVGGLLYLRRNNLEFIYNKTGWAMVSLCIVFAMTSGQMWNHIRGPPYAHKNPH 262
            L LL++++GGL+YLRR+N+EF++NKTGWA  +LC V AMTSGQMWNHIRGPPYAHKNPH
Sbjct: 223 MLGLLLAVIGGLVYLRRSNMEFLFNKTGWAFAALCFVLAMTSGQMWNHIRGPPYAHKNPH 282

Query: 263 NGQVSYIHGSSQAQFVAESHIILVLNAAITMGMVLLNEAATSKGDVGKRRIICLVGLGLV 322
            G V+YIHGSSQAQFVAE+HI+L+ N  +T+GMVLL EAATS  D+GKR+I+C+ G+GLV
Sbjct: 283 TGHVNYIHGSSQAQFVAETHIVLLFNGGVTLGMVLLCEAATSDMDIGKRKIMCVAGIGLV 342

Query: 323 VFFFSFLLSIFRSKYHGYPYSFLI 346
           V FFS++LSIFRSKYHGYPYSFL+
Sbjct: 343 VLFFSWMLSIFRSKYHGYPYSFLM 366


>gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo
            sapiens]
          Length = 2923

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 7/69 (10%)

Query: 277  FVAESHIILVLNAAITMGMVLLNEAATSKGDVGKRRIICLVGLG------LVVFFFSFLL 330
            F  ESH+    N  +T   VL++ +    G++   + +  V LG      L+ FFF  LL
Sbjct: 2343 FRNESHVSCQCNH-MTSFAVLMDVSRRENGEILPLKTLTYVALGVTLAALLLTFFFLTLL 2401

Query: 331  SIFRSKYHG 339
             I RS  HG
Sbjct: 2402 RILRSNQHG 2410


>gi|16933540 fibroblast activation protein, alpha subunit [Homo
           sapiens]
          Length = 760

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 34/179 (18%), Positives = 71/179 (39%), Gaps = 19/179 (10%)

Query: 44  KKENLLAEKVEQLMEWSSRR----SIFRMNGDKF----RKFIKAPPRNYSMIVMFTALQP 95
           K  + + + VE  ++ +S +    +IFR+  D       +F + P R     +   +  P
Sbjct: 375 KHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPP 434

Query: 96  QRQCSVCRQANEEYQILANSWRYSSAFCNKL-FFSMVDYDEGTDVFQQLNMNSAPTFMHF 154
            ++C  C    E  Q       Y+++F +   ++++V Y  G  +     ++   T    
Sbjct: 435 SKKCVTCHLRKERCQY------YTASFSDYAKYYALVCYGPGIPIS---TLHDGRTDQEI 485

Query: 155 PPKGRPKRADTFDLQRIGFAAEQLAKWIADRTDVHIRVFRPPNYSGTIALALLVSLVGG 213
                 K  +   L+ I    E++ K   D   +  ++  PP +  +    LL+ + GG
Sbjct: 486 KILEENKELENA-LKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGG 543


>gi|38569407 arylsulfatase B isoform 2 precursor [Homo sapiens]
          Length = 413

 Score = 29.3 bits (64), Expect = 5.4
 Identities = 21/49 (42%), Positives = 24/49 (48%), Gaps = 1/49 (2%)

Query: 1  MGARGAPSRRRQAGRRLRYLPTGSFPFLLLLLLLCIQLGGGQKKKENLL 49
          MG RGA S  R  G R   LP    P LLLLLL     G G  +  +L+
Sbjct: 1  MGPRGAASLPRGPGPRRLLLPV-VLPLLLLLLLAPPGSGAGASRPPHLV 48


>gi|38569405 arylsulfatase B isoform 1 precursor [Homo sapiens]
          Length = 533

 Score = 29.3 bits (64), Expect = 5.4
 Identities = 21/49 (42%), Positives = 24/49 (48%), Gaps = 1/49 (2%)

Query: 1  MGARGAPSRRRQAGRRLRYLPTGSFPFLLLLLLLCIQLGGGQKKKENLL 49
          MG RGA S  R  G R   LP    P LLLLLL     G G  +  +L+
Sbjct: 1  MGPRGAASLPRGPGPRRLLLPV-VLPLLLLLLLAPPGSGAGASRPPHLV 48


>gi|31563526 solute carrier family 24 (sodium/potassium/calcium
          exchanger), member 3 [Homo sapiens]
          Length = 644

 Score = 29.3 bits (64), Expect = 5.4
 Identities = 19/62 (30%), Positives = 31/62 (50%)

Query: 8  SRRRQAGRRLRYLPTGSFPFLLLLLLLCIQLGGGQKKKENLLAEKVEQLMEWSSRRSIFR 67
          +RRR+  RR R L      FL  + LL   L   +++KE  L + V +  +W   R + +
Sbjct: 10 ARRRRRRRRRRDLLLSQLCFLASVALLLWSLSSLREQKELDLMDLVGEDRKWMMARKLMQ 69

Query: 68 MN 69
          +N
Sbjct: 70 VN 71


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.139    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,321,411
Number of Sequences: 37866
Number of extensions: 559408
Number of successful extensions: 1652
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1646
Number of HSP's gapped (non-prelim): 10
length of query: 347
length of database: 18,247,518
effective HSP length: 103
effective length of query: 244
effective length of database: 14,347,320
effective search space: 3500746080
effective search space used: 3500746080
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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