Guide to the Human Genome
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Search of human proteins with 122937297

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|122937297 serpin peptidase inhibitor, clade A (alpha-1
antiproteinase, antitrypsin), member 11 [Homo sapiens]
         (422 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|122937297 serpin peptidase inhibitor, clade A (alpha-1 antipr...   848   0.0  
gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ...   341   8e-94
gi|21361302 serine (or cysteine) proteinase inhibitor, clade A (...   333   1e-91
gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,...   328   4e-90
gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur...   314   8e-86
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom...   313   1e-85
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom...   313   1e-85
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom...   313   1e-85
gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom...   313   1e-85
gi|189163534 serine proteinase inhibitor, clade A, member 1 [Hom...   313   1e-85
gi|189163532 serine proteinase inhibitor, clade A, member 1 [Hom...   313   1e-85
gi|189163530 serine proteinase inhibitor, clade A, member 1 [Hom...   313   1e-85
gi|189163528 serine proteinase inhibitor, clade A, member 1 [Hom...   313   1e-85
gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo...   313   1e-85
gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo...   313   1e-85
gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo...   313   1e-85
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ...   304   9e-83
gi|73858564 corticosteroid binding globulin precursor [Homo sapi...   287   1e-77
gi|27777657 serine (or cysteine) proteinase inhibitor, clade A (...   269   3e-72
gi|110225349 serine (or cysteine) proteinase inhibitor, clade A ...   216   3e-56
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o...   199   4e-51
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (...   199   5e-51
gi|4826902 serine (or cysteine) proteinase inhibitor, clade B (o...   185   6e-47
gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (...   175   8e-44
gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (...   168   7e-42
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s...   165   6e-41
gi|8393956 serine (or cysteine) proteinase inhibitor, clade B (o...   165   8e-41
gi|154759291 serine (or cysteine) proteinase inhibitor, clade A ...   162   5e-40
gi|7705879 serine (or cysteine) proteinase inhibitor, clade A (a...   162   5e-40
gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s...   160   2e-39

>gi|122937297 serpin peptidase inhibitor, clade A (alpha-1
           antiproteinase, antitrypsin), member 11 [Homo sapiens]
          Length = 422

 Score =  848 bits (2191), Expect = 0.0
 Identities = 422/422 (100%), Positives = 422/422 (100%)

Query: 1   MGPAWLWLLGTGILASVHCQPLLAHGDKSLQGPQPPRHQLSEPAPAYHRITPTITNFALR 60
           MGPAWLWLLGTGILASVHCQPLLAHGDKSLQGPQPPRHQLSEPAPAYHRITPTITNFALR
Sbjct: 1   MGPAWLWLLGTGILASVHCQPLLAHGDKSLQGPQPPRHQLSEPAPAYHRITPTITNFALR 60

Query: 61  LYKELAADAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFR 120
           LYKELAADAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFR
Sbjct: 61  LYKELAADAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFR 120

Query: 121 SLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQI 180
           SLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQI
Sbjct: 121 SLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQI 180

Query: 181 NDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSL 240
           NDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSL
Sbjct: 181 NDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSL 240

Query: 241 QVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRKWG 300
           QVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRKWG
Sbjct: 241 QVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRKWG 300

Query: 301 QLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSHKA 360
           QLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSHKA
Sbjct: 301 QLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSHKA 360

Query: 361 MVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVNPV 420
           MVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVNPV
Sbjct: 361 MVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVNPV 420

Query: 421 AG 422
           AG
Sbjct: 421 AG 422


>gi|110225347 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 9 isoform
           A [Homo sapiens]
          Length = 435

 Score =  341 bits (874), Expect = 8e-94
 Identities = 185/411 (45%), Positives = 265/411 (64%), Gaps = 6/411 (1%)

Query: 12  GILASVH-CQPLLAHGDKSLQGPQP-PRHQLSEPAPAYHRITPTITNFALRLYKELAADA 69
           G+L +V  C P+      +     P P    S PA   + +    T+FA RLY+ L  + 
Sbjct: 25  GVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPASQVYSLN---TDFAFRLYRRLVLET 81

Query: 70  PG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFRSLLHTLAL 128
           P  NIFFSPVS+ST+LA+LSLGA + T   IL+GLGFNLT TPE+ IHQGF+ L+H+L +
Sbjct: 82  PSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQHLVHSLTV 141

Query: 129 PSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQINDYLRRQT 188
           PS  L LK+G++LF+ K L+ + ++L ++K LY A  FS +F++      +IN +++++T
Sbjct: 142 PSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARINSHVKKKT 201

Query: 189 YGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQVPMMHQK 248
            G+VVD +      T MVL N+IFFKAKW+ PF    T+K   F V E+ ++ VPMMHQK
Sbjct: 202 QGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQK 261

Query: 249 EMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRKWGQLLLPSLL 308
           E   F  D +L C VLQ++Y+G+A+A  VLP  GKM+Q+E AL  +TLRKW   L    +
Sbjct: 262 EQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSHSLQKRWI 321

Query: 309 DLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSHKAMVDMSEKG 368
           ++ +PRFSIS +YNLE ILP++G+ N+ +  ADFSG+  + +  +SK +HKA++D+SE+G
Sbjct: 322 EVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVSEEG 381

Query: 369 TEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVNP 419
           TEA AA+       S +  S     FNR FL+++    T  +LFLGKV NP
Sbjct: 382 TEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENP 432


>gi|21361302 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 4 [Homo
           sapiens]
          Length = 427

 Score =  333 bits (855), Expect = 1e-91
 Identities = 187/422 (44%), Positives = 275/422 (65%), Gaps = 10/422 (2%)

Query: 5   WLWLLGTGILASVHCQPLLAHGDKSLQGPQPPRH-QLSEPAPAYHRITPTITNFALRLYK 63
           +L LL  G+LA  H Q  + H  +S       +  +  E +P+  +I P   +FA R Y 
Sbjct: 6   YLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSL-KIAPANADFAFRFYY 64

Query: 64  ELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFRSL 122
            +A++ PG NIFFSP+SIS   A+LSLGA +++ + ILEGLGFNLTE  E+D+H+GF+ L
Sbjct: 65  LIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHL 124

Query: 123 LHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQIND 182
           LHTL LP   LE +VG++LFL   LK    +L+    +Y A  F  NF D+V T + IND
Sbjct: 125 LHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLIND 184

Query: 183 YLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQV 242
           +++++T G++VD + E  +D  MVL NYI+FKA W+ PF   +T  ++ F+VDE T+++V
Sbjct: 185 HVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKD-FYVDENTTVRV 243

Query: 243 PMMHQ-KEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRKWGQ 301
           PMM Q +E H +L+D+ L C+VL+++Y+G+A    +LP+ GKM+++E  L P+ L +W  
Sbjct: 244 PMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMRWNN 303

Query: 302 LL----LPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVS 357
           LL        L+LHLP+FSISG+Y L+ ILP++G T++ +  AD SG+T Q     SK  
Sbjct: 304 LLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSF 363

Query: 358 HKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVV 417
           HKA +D+ E GTEA AA+    +  S  T +     FNRPFL++++  +TQS+LFLGKVV
Sbjct: 364 HKATLDVDEAGTEAAAATSFAIKFFSAQT-NRHILRFNRPFLVVIFSTSTQSVLFLGKVV 422

Query: 418 NP 419
           +P
Sbjct: 423 DP 424


>gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,
           member 7 [Homo sapiens]
          Length = 415

 Score =  328 bits (842), Expect = 4e-90
 Identities = 180/417 (43%), Positives = 260/417 (62%), Gaps = 12/417 (2%)

Query: 5   WLWLLGTGILASVHCQPLLAHGDKSLQGPQPPRHQLSEPAPAYHRITPTITNFALRLYKE 64
           +L LL  G+ A++HC         S +G     H  S+P    ++++    +FA  LY+ 
Sbjct: 6   YLVLLVLGLHATIHCA--------SPEGKVTACHS-SQPNATLYKMSSINADFAFNLYRR 56

Query: 65  LAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFRSLL 123
              + P  NIFFSPVSIS  L +LS GA  +T   I+E LGFNLT+TP  +I  GF+ L+
Sbjct: 57  FTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLI 116

Query: 124 HTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQINDY 183
            +L  P  +LEL++GN+LF+ K LKP   +L+ +K LY    FS +F++     ++IN +
Sbjct: 117 CSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSH 176

Query: 184 LRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQVP 243
           +  QT G+VV  + +   +T MVL NYI FKA+W +PF   +T+   SF +D+ T++QVP
Sbjct: 177 VEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVP 236

Query: 244 MMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRKWGQLL 303
           MMHQ E +  L D +L CTVLQ++Y  NALAL VLP  G+M+ VEAA+  +TL+KW +LL
Sbjct: 237 MMHQMEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLL 296

Query: 304 LPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSHKAMVD 363
               +DL +P+FSIS TY+L   L ++G+ +  +  ADFSG+T      +S  +HKA++ 
Sbjct: 297 QKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLH 356

Query: 364 MSEKGTEAGAASGL-LSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVNP 419
           + EKGTEA A   + LS  P  NT   P    +R F+LL+ E +T+S+LFLGKVVNP
Sbjct: 357 IGEKGTEAAAVPEVELSDQPE-NTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNP 412


>gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor
           [Homo sapiens]
          Length = 423

 Score =  314 bits (805), Expect = 8e-86
 Identities = 172/415 (41%), Positives = 249/415 (60%), Gaps = 4/415 (0%)

Query: 8   LLGTGILASVHCQPLLAHGDKSLQGPQPPRHQLSEPAPAYHRITPTITNFALRLYKELAA 67
           LL  G+LA+  C  +L H +  L      +            +     +FA  LYK+L  
Sbjct: 7   LLALGLLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSLYKQLVL 66

Query: 68  DAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFRSLLHTL 126
            AP  N+ FSP+SIST LA LSLGA   T   IL+GL FNLTET EA+IHQ F+ LL TL
Sbjct: 67  KAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTL 126

Query: 127 ALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQINDYLRR 186
              S +L+L +GN++F+ ++L     + +  K LYG+ AF+ +F DS    + INDY++ 
Sbjct: 127 NQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKN 186

Query: 187 QTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQVPMMH 246
            T G++ D + +    T MVL NYIFFKAKW+ PF    T  Q  F++ ++  + VPMM 
Sbjct: 187 GTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTH-QSRFYLSKKKWVMVPMMS 245

Query: 247 QKEMH-RFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRKW-GQLLL 304
              +   +  D++L+CTV++++Y GNA AL +LPD  KM++VEA L P+TL++W   L  
Sbjct: 246 LHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEF 305

Query: 305 PSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSHKAMVDM 364
             + +L+LP+FSIS  YNL DIL Q+G+      +AD SG+TG  N  +S+V HKA++D+
Sbjct: 306 REIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDV 365

Query: 365 SEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVNP 419
            E+GTEA AA+ +     S    +     FNRPFL+++    TQ++ F+ KV NP
Sbjct: 366 FEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNP 420


>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  313 bits (803), Expect = 1e-85
 Identities = 169/376 (44%), Positives = 240/376 (63%), Gaps = 6/376 (1%)

Query: 45  PAYHRITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGL 103
           P +++ITP +  FA  LY++LA  +   NIFFSPVSI+T  A+LSLG +A+T   ILEGL
Sbjct: 45  PTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGL 104

Query: 104 GFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGA 163
            FNLTE PEA IH+GF+ LL TL  P  +L+L  GN LFL + LK    +L+ +K+LY +
Sbjct: 105 NFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164

Query: 164 FAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSR 223
            AF+ NF D+    +QINDY+ + T G++VD + E  +DT   L NYIFFK KW+ PF  
Sbjct: 165 EAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEV 224

Query: 224 YQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGK 283
             T+ +E F VD+ T+++VPMM +  M    + + L+  VL ++Y GNA A+  LPD GK
Sbjct: 225 KDTE-EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGK 283

Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS 343
           ++ +E  L    + K+ +        LHLP+ SI+GTY+L+ +L Q+G+T + +  AD S
Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343

Query: 344 GVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLW 403
           GVT +    +SK  HKA++ + EKGTEA  A  L + P S+     P   FN+PF+ L+ 
Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSI----PPEVKFNKPFVFLMI 399

Query: 404 EVTTQSLLFLGKVVNP 419
           E  T+S LF+GKVVNP
Sbjct: 400 EQNTKSPLFMGKVVNP 415


>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  313 bits (803), Expect = 1e-85
 Identities = 169/376 (44%), Positives = 240/376 (63%), Gaps = 6/376 (1%)

Query: 45  PAYHRITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGL 103
           P +++ITP +  FA  LY++LA  +   NIFFSPVSI+T  A+LSLG +A+T   ILEGL
Sbjct: 45  PTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGL 104

Query: 104 GFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGA 163
            FNLTE PEA IH+GF+ LL TL  P  +L+L  GN LFL + LK    +L+ +K+LY +
Sbjct: 105 NFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164

Query: 164 FAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSR 223
            AF+ NF D+    +QINDY+ + T G++VD + E  +DT   L NYIFFK KW+ PF  
Sbjct: 165 EAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEV 224

Query: 224 YQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGK 283
             T+ +E F VD+ T+++VPMM +  M    + + L+  VL ++Y GNA A+  LPD GK
Sbjct: 225 KDTE-EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGK 283

Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS 343
           ++ +E  L    + K+ +        LHLP+ SI+GTY+L+ +L Q+G+T + +  AD S
Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343

Query: 344 GVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLW 403
           GVT +    +SK  HKA++ + EKGTEA  A  L + P S+     P   FN+PF+ L+ 
Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSI----PPEVKFNKPFVFLMI 399

Query: 404 EVTTQSLLFLGKVVNP 419
           E  T+S LF+GKVVNP
Sbjct: 400 EQNTKSPLFMGKVVNP 415


>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  313 bits (803), Expect = 1e-85
 Identities = 169/376 (44%), Positives = 240/376 (63%), Gaps = 6/376 (1%)

Query: 45  PAYHRITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGL 103
           P +++ITP +  FA  LY++LA  +   NIFFSPVSI+T  A+LSLG +A+T   ILEGL
Sbjct: 45  PTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGL 104

Query: 104 GFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGA 163
            FNLTE PEA IH+GF+ LL TL  P  +L+L  GN LFL + LK    +L+ +K+LY +
Sbjct: 105 NFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164

Query: 164 FAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSR 223
            AF+ NF D+    +QINDY+ + T G++VD + E  +DT   L NYIFFK KW+ PF  
Sbjct: 165 EAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEV 224

Query: 224 YQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGK 283
             T+ +E F VD+ T+++VPMM +  M    + + L+  VL ++Y GNA A+  LPD GK
Sbjct: 225 KDTE-EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGK 283

Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS 343
           ++ +E  L    + K+ +        LHLP+ SI+GTY+L+ +L Q+G+T + +  AD S
Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343

Query: 344 GVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLW 403
           GVT +    +SK  HKA++ + EKGTEA  A  L + P S+     P   FN+PF+ L+ 
Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSI----PPEVKFNKPFVFLMI 399

Query: 404 EVTTQSLLFLGKVVNP 419
           E  T+S LF+GKVVNP
Sbjct: 400 EQNTKSPLFMGKVVNP 415


>gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  313 bits (803), Expect = 1e-85
 Identities = 169/376 (44%), Positives = 240/376 (63%), Gaps = 6/376 (1%)

Query: 45  PAYHRITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGL 103
           P +++ITP +  FA  LY++LA  +   NIFFSPVSI+T  A+LSLG +A+T   ILEGL
Sbjct: 45  PTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGL 104

Query: 104 GFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGA 163
            FNLTE PEA IH+GF+ LL TL  P  +L+L  GN LFL + LK    +L+ +K+LY +
Sbjct: 105 NFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164

Query: 164 FAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSR 223
            AF+ NF D+    +QINDY+ + T G++VD + E  +DT   L NYIFFK KW+ PF  
Sbjct: 165 EAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEV 224

Query: 224 YQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGK 283
             T+ +E F VD+ T+++VPMM +  M    + + L+  VL ++Y GNA A+  LPD GK
Sbjct: 225 KDTE-EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGK 283

Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS 343
           ++ +E  L    + K+ +        LHLP+ SI+GTY+L+ +L Q+G+T + +  AD S
Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343

Query: 344 GVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLW 403
           GVT +    +SK  HKA++ + EKGTEA  A  L + P S+     P   FN+PF+ L+ 
Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSI----PPEVKFNKPFVFLMI 399

Query: 404 EVTTQSLLFLGKVVNP 419
           E  T+S LF+GKVVNP
Sbjct: 400 EQNTKSPLFMGKVVNP 415


>gi|189163534 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  313 bits (803), Expect = 1e-85
 Identities = 169/376 (44%), Positives = 240/376 (63%), Gaps = 6/376 (1%)

Query: 45  PAYHRITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGL 103
           P +++ITP +  FA  LY++LA  +   NIFFSPVSI+T  A+LSLG +A+T   ILEGL
Sbjct: 45  PTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGL 104

Query: 104 GFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGA 163
            FNLTE PEA IH+GF+ LL TL  P  +L+L  GN LFL + LK    +L+ +K+LY +
Sbjct: 105 NFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164

Query: 164 FAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSR 223
            AF+ NF D+    +QINDY+ + T G++VD + E  +DT   L NYIFFK KW+ PF  
Sbjct: 165 EAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEV 224

Query: 224 YQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGK 283
             T+ +E F VD+ T+++VPMM +  M    + + L+  VL ++Y GNA A+  LPD GK
Sbjct: 225 KDTE-EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGK 283

Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS 343
           ++ +E  L    + K+ +        LHLP+ SI+GTY+L+ +L Q+G+T + +  AD S
Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343

Query: 344 GVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLW 403
           GVT +    +SK  HKA++ + EKGTEA  A  L + P S+     P   FN+PF+ L+ 
Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSI----PPEVKFNKPFVFLMI 399

Query: 404 EVTTQSLLFLGKVVNP 419
           E  T+S LF+GKVVNP
Sbjct: 400 EQNTKSPLFMGKVVNP 415


>gi|189163532 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  313 bits (803), Expect = 1e-85
 Identities = 169/376 (44%), Positives = 240/376 (63%), Gaps = 6/376 (1%)

Query: 45  PAYHRITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGL 103
           P +++ITP +  FA  LY++LA  +   NIFFSPVSI+T  A+LSLG +A+T   ILEGL
Sbjct: 45  PTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGL 104

Query: 104 GFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGA 163
            FNLTE PEA IH+GF+ LL TL  P  +L+L  GN LFL + LK    +L+ +K+LY +
Sbjct: 105 NFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164

Query: 164 FAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSR 223
            AF+ NF D+    +QINDY+ + T G++VD + E  +DT   L NYIFFK KW+ PF  
Sbjct: 165 EAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEV 224

Query: 224 YQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGK 283
             T+ +E F VD+ T+++VPMM +  M    + + L+  VL ++Y GNA A+  LPD GK
Sbjct: 225 KDTE-EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGK 283

Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS 343
           ++ +E  L    + K+ +        LHLP+ SI+GTY+L+ +L Q+G+T + +  AD S
Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343

Query: 344 GVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLW 403
           GVT +    +SK  HKA++ + EKGTEA  A  L + P S+     P   FN+PF+ L+ 
Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSI----PPEVKFNKPFVFLMI 399

Query: 404 EVTTQSLLFLGKVVNP 419
           E  T+S LF+GKVVNP
Sbjct: 400 EQNTKSPLFMGKVVNP 415


>gi|189163530 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  313 bits (803), Expect = 1e-85
 Identities = 169/376 (44%), Positives = 240/376 (63%), Gaps = 6/376 (1%)

Query: 45  PAYHRITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGL 103
           P +++ITP +  FA  LY++LA  +   NIFFSPVSI+T  A+LSLG +A+T   ILEGL
Sbjct: 45  PTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGL 104

Query: 104 GFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGA 163
            FNLTE PEA IH+GF+ LL TL  P  +L+L  GN LFL + LK    +L+ +K+LY +
Sbjct: 105 NFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164

Query: 164 FAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSR 223
            AF+ NF D+    +QINDY+ + T G++VD + E  +DT   L NYIFFK KW+ PF  
Sbjct: 165 EAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEV 224

Query: 224 YQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGK 283
             T+ +E F VD+ T+++VPMM +  M    + + L+  VL ++Y GNA A+  LPD GK
Sbjct: 225 KDTE-EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGK 283

Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS 343
           ++ +E  L    + K+ +        LHLP+ SI+GTY+L+ +L Q+G+T + +  AD S
Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343

Query: 344 GVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLW 403
           GVT +    +SK  HKA++ + EKGTEA  A  L + P S+     P   FN+PF+ L+ 
Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSI----PPEVKFNKPFVFLMI 399

Query: 404 EVTTQSLLFLGKVVNP 419
           E  T+S LF+GKVVNP
Sbjct: 400 EQNTKSPLFMGKVVNP 415


>gi|189163528 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  313 bits (803), Expect = 1e-85
 Identities = 169/376 (44%), Positives = 240/376 (63%), Gaps = 6/376 (1%)

Query: 45  PAYHRITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGL 103
           P +++ITP +  FA  LY++LA  +   NIFFSPVSI+T  A+LSLG +A+T   ILEGL
Sbjct: 45  PTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGL 104

Query: 104 GFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGA 163
            FNLTE PEA IH+GF+ LL TL  P  +L+L  GN LFL + LK    +L+ +K+LY +
Sbjct: 105 NFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164

Query: 164 FAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSR 223
            AF+ NF D+    +QINDY+ + T G++VD + E  +DT   L NYIFFK KW+ PF  
Sbjct: 165 EAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEV 224

Query: 224 YQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGK 283
             T+ +E F VD+ T+++VPMM +  M    + + L+  VL ++Y GNA A+  LPD GK
Sbjct: 225 KDTE-EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGK 283

Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS 343
           ++ +E  L    + K+ +        LHLP+ SI+GTY+L+ +L Q+G+T + +  AD S
Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343

Query: 344 GVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLW 403
           GVT +    +SK  HKA++ + EKGTEA  A  L + P S+     P   FN+PF+ L+ 
Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSI----PPEVKFNKPFVFLMI 399

Query: 404 EVTTQSLLFLGKVVNP 419
           E  T+S LF+GKVVNP
Sbjct: 400 EQNTKSPLFMGKVVNP 415


>gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  313 bits (803), Expect = 1e-85
 Identities = 169/376 (44%), Positives = 240/376 (63%), Gaps = 6/376 (1%)

Query: 45  PAYHRITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGL 103
           P +++ITP +  FA  LY++LA  +   NIFFSPVSI+T  A+LSLG +A+T   ILEGL
Sbjct: 45  PTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGL 104

Query: 104 GFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGA 163
            FNLTE PEA IH+GF+ LL TL  P  +L+L  GN LFL + LK    +L+ +K+LY +
Sbjct: 105 NFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164

Query: 164 FAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSR 223
            AF+ NF D+    +QINDY+ + T G++VD + E  +DT   L NYIFFK KW+ PF  
Sbjct: 165 EAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEV 224

Query: 224 YQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGK 283
             T+ +E F VD+ T+++VPMM +  M    + + L+  VL ++Y GNA A+  LPD GK
Sbjct: 225 KDTE-EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGK 283

Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS 343
           ++ +E  L    + K+ +        LHLP+ SI+GTY+L+ +L Q+G+T + +  AD S
Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343

Query: 344 GVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLW 403
           GVT +    +SK  HKA++ + EKGTEA  A  L + P S+     P   FN+PF+ L+ 
Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSI----PPEVKFNKPFVFLMI 399

Query: 404 EVTTQSLLFLGKVVNP 419
           E  T+S LF+GKVVNP
Sbjct: 400 EQNTKSPLFMGKVVNP 415


>gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  313 bits (803), Expect = 1e-85
 Identities = 169/376 (44%), Positives = 240/376 (63%), Gaps = 6/376 (1%)

Query: 45  PAYHRITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGL 103
           P +++ITP +  FA  LY++LA  +   NIFFSPVSI+T  A+LSLG +A+T   ILEGL
Sbjct: 45  PTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGL 104

Query: 104 GFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGA 163
            FNLTE PEA IH+GF+ LL TL  P  +L+L  GN LFL + LK    +L+ +K+LY +
Sbjct: 105 NFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164

Query: 164 FAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSR 223
            AF+ NF D+    +QINDY+ + T G++VD + E  +DT   L NYIFFK KW+ PF  
Sbjct: 165 EAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEV 224

Query: 224 YQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGK 283
             T+ +E F VD+ T+++VPMM +  M    + + L+  VL ++Y GNA A+  LPD GK
Sbjct: 225 KDTE-EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGK 283

Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS 343
           ++ +E  L    + K+ +        LHLP+ SI+GTY+L+ +L Q+G+T + +  AD S
Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343

Query: 344 GVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLW 403
           GVT +    +SK  HKA++ + EKGTEA  A  L + P S+     P   FN+PF+ L+ 
Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSI----PPEVKFNKPFVFLMI 399

Query: 404 EVTTQSLLFLGKVVNP 419
           E  T+S LF+GKVVNP
Sbjct: 400 EQNTKSPLFMGKVVNP 415


>gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  313 bits (803), Expect = 1e-85
 Identities = 169/376 (44%), Positives = 240/376 (63%), Gaps = 6/376 (1%)

Query: 45  PAYHRITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGL 103
           P +++ITP +  FA  LY++LA  +   NIFFSPVSI+T  A+LSLG +A+T   ILEGL
Sbjct: 45  PTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGL 104

Query: 104 GFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGA 163
            FNLTE PEA IH+GF+ LL TL  P  +L+L  GN LFL + LK    +L+ +K+LY +
Sbjct: 105 NFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164

Query: 164 FAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSR 223
            AF+ NF D+    +QINDY+ + T G++VD + E  +DT   L NYIFFK KW+ PF  
Sbjct: 165 EAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEV 224

Query: 224 YQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGK 283
             T+ +E F VD+ T+++VPMM +  M    + + L+  VL ++Y GNA A+  LPD GK
Sbjct: 225 KDTE-EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGK 283

Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS 343
           ++ +E  L    + K+ +        LHLP+ SI+GTY+L+ +L Q+G+T + +  AD S
Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343

Query: 344 GVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLW 403
           GVT +    +SK  HKA++ + EKGTEA  A  L + P S+     P   FN+PF+ L+ 
Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSI----PPEVKFNKPFVFLMI 399

Query: 404 EVTTQSLLFLGKVVNP 419
           E  T+S LF+GKVVNP
Sbjct: 400 EQNTKSPLFMGKVVNP 415


>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 5 [Homo
           sapiens]
          Length = 406

 Score =  304 bits (779), Expect = 9e-83
 Identities = 168/415 (40%), Positives = 255/415 (61%), Gaps = 12/415 (2%)

Query: 6   LWLLGTGILASVHCQPLLAHGDKSLQGPQPPRHQLSEPAPAYHRITPTITNFALRLYKEL 65
           L+LL   +L S     L  H  + ++      H  +  AP+  R      +F   LY+ L
Sbjct: 3   LFLLLCLVLLSPQGASLHRHHPREMKKRVEDLHVGATVAPSSRR------DFTFDLYRAL 56

Query: 66  AADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFRSLLH 124
           A+ AP  +IFFSPVSIS +LA+LSLGA ++T   ILEGLG NL ++ E ++H+GF+ LL 
Sbjct: 57  ASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQ 116

Query: 125 TLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQINDYL 184
            L  P    +L +GN+LF D  +  +  ++ ++K LY A  F  NF DS    +QINDY+
Sbjct: 117 ELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYV 176

Query: 185 RRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQVPM 244
            +QT G++VD L     +  +++ NYIFFKAKW+  F+   TQ+Q+ F+V   T ++VPM
Sbjct: 177 AKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQD-FYVTSETVVRVPM 235

Query: 245 MHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRKWGQLLL 304
           M +++ + +L D++L+C V+ + Y+GNA AL +LP  GKM+QVE  L  +TLRKW ++  
Sbjct: 236 MSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFK 295

Query: 305 PSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSHKAMVDM 364
              L+L+LP+FSI G+Y LE +LP +G++N+    AD SG++   N  +S++ HKA+V++
Sbjct: 296 KRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEV 355

Query: 365 SEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVNP 419
            E GT A AA+G +    S   ++     FNRPFL+    +   ++LFLGKV  P
Sbjct: 356 DESGTRAAAATGTIFTFRSAR-LNSQRLVFNRPFLMF---IVDNNILFLGKVNRP 406


>gi|73858564 corticosteroid binding globulin precursor [Homo
           sapiens]
          Length = 405

 Score =  287 bits (734), Expect = 1e-77
 Identities = 159/391 (40%), Positives = 232/391 (59%), Gaps = 15/391 (3%)

Query: 39  QLSEPAPAY------HR-ITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLG 90
           Q  +P  AY      HR +     +FA  LYK L A +P  NIF SPVSIS  LA+LSLG
Sbjct: 21  QAMDPNAAYVNMSNHHRGLASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLG 80

Query: 91  AQANTSALILEGLGFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPR 150
              +T A +L+GLGFNLTE  E +IHQGF+ L    A     LE+ +GN+LFLD  L+  
Sbjct: 81  TCGHTRAQLLQGLGFNLTERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELL 140

Query: 151 QHYLDSIKELYGAFAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANY 210
           + +   IK  Y +   + NF D  T  RQIN Y++ +T G++VD          +VL NY
Sbjct: 141 ESFSADIKHYYESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNY 200

Query: 211 IFFKAKWKHPFSRYQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRG 270
           IFFK  W  PF    T ++E+F+VDE T ++VPMM Q     +L+D +L C ++Q+ Y G
Sbjct: 201 IFFKGTWTQPFDLAST-REENFYVDETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVG 259

Query: 271 NALALLVLPDPGKMKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQI 330
           N     +LPD GKM  V AAL   T+ +W   L  S +DL++P+ +ISG Y+L D+L ++
Sbjct: 260 NGTVFFILPDKGKMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEM 319

Query: 331 GLTNILNLEADFSGVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDP 390
           G+ ++   +A+FS +T       SKV HKA++ ++E+G +   ++G+     +LN  S P
Sbjct: 320 GIADLFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGV-----TLNLTSKP 374

Query: 391 -HAHFNRPFLLLLWEVTTQSLLFLGKVVNPV 420
               FN+PF++++++  T S LFL +V+NPV
Sbjct: 375 IILRFNQPFIIMIFDHFTWSSLFLARVMNPV 405


>gi|27777657 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 12 [Homo
           sapiens]
          Length = 414

 Score =  269 bits (688), Expect = 3e-72
 Identities = 139/367 (37%), Positives = 225/367 (61%), Gaps = 10/367 (2%)

Query: 56  NFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEAD 114
           +   +L K+LA   PG NIF SP+SIST  ++L LGAQ +T   I +G  FN  + PE D
Sbjct: 54  DLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQG--FNFRKMPEKD 111

Query: 115 IHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSV 174
           +H+GF  ++H L   +  L+L +GN+LF+D+RL+P++ +L+  K  Y A     NF +  
Sbjct: 112 LHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLE 171

Query: 175 TTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFV 234
              +QIND++ ++T+G++ + +      T M+LANYIFF+A+WKH F    T K+E FF+
Sbjct: 172 MAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVT-KEEDFFL 230

Query: 235 DERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQ 294
           ++ +S++VPMM +  +++  YD  L+CT+L+I Y+ N  A+ +LPD GK+K +E  LQ  
Sbjct: 231 EKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVD 290

Query: 295 TLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTIS 354
           T  +W  LL   ++D+ +PR  ++GT++L+  L  IG++ I     D + +    +  + 
Sbjct: 291 TFSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVG 350

Query: 355 KVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDP-HAHFNRPFLLLLWEVTTQSLLFL 413
           +  HKA + M E+GTE  A +G  + P     M  P     ++P+LLL++     S+LFL
Sbjct: 351 EAVHKAELKMDERGTEGAAGTGAQTLP-----METPLVVKIDKPYLLLIYSEKIPSVLFL 405

Query: 414 GKVVNPV 420
           GK+VNP+
Sbjct: 406 GKIVNPI 412


>gi|110225349 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 9 isoform
           B [Homo sapiens]
          Length = 335

 Score =  216 bits (550), Expect = 3e-56
 Identities = 111/241 (46%), Positives = 159/241 (65%)

Query: 179 QINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERT 238
           +IN +++++T G+VVD +      T MVL N+IFFKAKW+ PF    T+K   F V E+ 
Sbjct: 92  RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151

Query: 239 SLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRK 298
           ++ VPMMHQKE   F  D +L C VLQ++Y+G+A+A  VLP  GKM+Q+E AL  +TLRK
Sbjct: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211

Query: 299 WGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSH 358
           W   L    +++ +PRFSIS +YNLE ILP++G+ N+ +  ADFSG+  + +  +SK +H
Sbjct: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271

Query: 359 KAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVN 418
           KA++D+SE+GTEA AA+       S +  S     FNR FL+++    T  +LFLGKV N
Sbjct: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331

Query: 419 P 419
           P
Sbjct: 332 P 332



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 6/74 (8%)

Query: 12 GILASVH-CQPLLAHGDKSLQGPQP-PRHQLSEPAPAYHRITPTITNFALRLYKELAADA 69
          G+L +V  C P+      +     P P    S PA   + +    T+FA RLY+ L  + 
Sbjct: 25 GVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPASQVYSLN---TDFAFRLYRRLVLET 81

Query: 70 PG-NIFFSPVSIST 82
          P  NIFFSP  I++
Sbjct: 82 PSQNIFFSPARINS 95


>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 3 [Homo sapiens]
          Length = 390

 Score =  199 bits (506), Expect = 4e-51
 Identities = 125/384 (32%), Positives = 210/384 (54%), Gaps = 21/384 (5%)

Query: 55  TNFALRLYKELAADAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFN-LTETP-- 111
           T F   L+++       NIF+SP+SI++ L ++ LGA+ NT+  I + L F+ +TE    
Sbjct: 9   TKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVTENTTG 68

Query: 112 ---------EADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYG 162
                      ++H  F+ LL      +   ELK+ N LF +K     Q YLD+IK+ Y 
Sbjct: 69  KAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDAIKKFYQ 128

Query: 163 AFAFSANFTDSVTTGRQ-INDYLRRQTYGQVVDCLPE--FSQDTFMVLANYIFFKAKWKH 219
               S +F ++    R+ IN ++  QT  ++ + +PE     +T +VL N I+FK +W+ 
Sbjct: 129 TSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYFKGQWEK 188

Query: 220 PFSRYQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVL- 278
            F++  T K+E F+ ++ T   + MM Q     F   +D+   VL+I Y+G  L+++VL 
Sbjct: 189 KFNKEDT-KEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGKDLSMIVLL 247

Query: 279 -PDPGKMKQVEAALQPQTLRKWGQL--LLPSLLDLHLPRFSISGTYNLEDILPQIGLTNI 335
             +   ++++E  L  + L +W  L  +  + +DLHLPRF +  +Y+L+D L  +G+ +I
Sbjct: 248 PNEIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRTMGMVDI 307

Query: 336 LNLEADFSGVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFN 395
            N +AD SG+TG     +S V HKA V+++E+G EA AA+ ++    S  T ++   H N
Sbjct: 308 FNGDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSS-PTSTNEEFHCN 366

Query: 396 RPFLLLLWEVTTQSLLFLGKVVNP 419
            PFL  + +  T S+LF G+  +P
Sbjct: 367 HPFLFFIRQNKTNSILFYGRFSSP 390


>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 4 [Homo sapiens]
          Length = 390

 Score =  199 bits (505), Expect = 5e-51
 Identities = 126/384 (32%), Positives = 209/384 (54%), Gaps = 21/384 (5%)

Query: 55  TNFALRLYKELAADAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGF-----NLTE 109
           T F   L+++       NIF+SP+SI++ L ++ LGA+ NT+  I + L F     N TE
Sbjct: 9   TKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQVTENTTE 68

Query: 110 TP-------EADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYG 162
                      ++H  F+ LL      +   ELK+ N LF +K  +  Q YLD+IK+ Y 
Sbjct: 69  KAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDAIKKFYQ 128

Query: 163 AFAFSANFTDSVTTGRQ-INDYLRRQTYGQVVDCLPE--FSQDTFMVLANYIFFKAKWKH 219
               S +F ++    R+ IN ++  QT  ++ +  P+     DT +VL N I+FK +W++
Sbjct: 129 TSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIYFKGQWEN 188

Query: 220 PFSRYQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVL- 278
            F +  T K+E F+ ++ T   V MM Q     F   +D+   VL+I Y+G  L+++VL 
Sbjct: 189 KFKKENT-KEEKFWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGKDLSMIVLL 247

Query: 279 -PDPGKMKQVEAALQPQTLRKWGQL--LLPSLLDLHLPRFSISGTYNLEDILPQIGLTNI 335
             +   ++++E  L  + L +W  L  +  + +DLHLPRF +  +Y+L+D L  +G+ NI
Sbjct: 248 PNEIDGLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLRTMGMVNI 307

Query: 336 LNLEADFSGVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFN 395
            N +AD SG+T     ++SKV HKA V+++E+G EA AA+ ++    S  + ++     N
Sbjct: 308 FNGDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSPSTNEEFC-CN 366

Query: 396 RPFLLLLWEVTTQSLLFLGKVVNP 419
            PFL  + +  T S+LF G+  +P
Sbjct: 367 HPFLFFIRQNKTNSILFYGRFSSP 390


>gi|4826902 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 10 [Homo sapiens]
          Length = 397

 Score =  185 bits (470), Expect = 6e-47
 Identities = 127/397 (31%), Positives = 210/397 (52%), Gaps = 30/397 (7%)

Query: 50  ITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLT 108
           +  +I  FAL L K+LA  A G NIFFS  SIST+L ++ LGA+  T+A + + L FN  
Sbjct: 4   LATSINQFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNRD 63

Query: 109 ETPEAD------------------IHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPR 150
           +  + D                  IH  F++L+  +  P+    LK  N+++ +K     
Sbjct: 64  QGVKCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTYAFH 123

Query: 151 QHYLDSIKELYGAFAFSANFTDSVTTGRQ-INDYLRRQTYGQVVDCLPEFSQD--TFMVL 207
             YL+ +K  +GA     NF ++    R+ IN ++ RQT G++ + LP+ S D  T M+L
Sbjct: 124 NKYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTRMIL 183

Query: 208 ANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIE 267
            N ++FK  W+H F   Q   ++ F ++E TS  V MM  K+     + +      LQ+ 
Sbjct: 184 VNALYFKGIWEHQFL-VQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQLY 242

Query: 268 YRGNALALLVL--PDPGKMKQVEAALQPQTLRKWGQLLLPSLLD--LHLPRFSISGTYNL 323
           Y+   L+LL+L   D   ++Q+E A+  + L +W    +  L +  LHLP+F +  +Y+L
Sbjct: 243 YKSRDLSLLILLPEDINGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKLEDSYDL 302

Query: 324 EDILPQIGLTNILNL-EADFSGVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPP 382
           +  L  +G+++  +  +ADFSG++   N  +S V HKA V+++E+GTEA A SG  S+  
Sbjct: 303 KSTLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGSG--SEID 360

Query: 383 SLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVNP 419
               +     + N PFL  +    T ++LF G++ +P
Sbjct: 361 IRIRVPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP 397


>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 1 [Homo sapiens]
          Length = 379

 Score =  175 bits (443), Expect = 8e-44
 Identities = 124/381 (32%), Positives = 209/381 (54%), Gaps = 26/381 (6%)

Query: 55  TNFALRLYKELAADAP-GNIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEA 113
           T FAL L+  L+ + P GNIF SP SIS+ +A++ LG + NT+A + +   FN  E    
Sbjct: 9   TRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNTVE---- 64

Query: 114 DIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDS 173
           ++H  F+SL   +        LK+ N L+ +K       +L S ++ YGA   S +F  +
Sbjct: 65  EVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHA 124

Query: 174 VTTGRQ-INDYLRRQTYGQVVDCLPEFSQD--TFMVLANYIFFKAKWKHPFSRYQTQKQE 230
               R+ IN +++ QT G++ + L     D  T +VL N I+FK  WK  F +  T    
Sbjct: 125 SEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAP 184

Query: 231 SFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVL-PDPGK-----M 284
            F ++++    V MM+QK+   + Y +DL C VL++ Y+G  L++++L PD  +     +
Sbjct: 185 -FRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDESTGL 243

Query: 285 KQVEAALQPQTLRKWGQLLLPSLLD-----LHLPRFSISGTYNLEDILPQIGLTNILNL- 338
           K++E  L  + L +W +   P  LD     + LPRF +  +Y L   L ++G+ ++ N  
Sbjct: 244 KKIEEQLTLEKLHEWTK---PENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS 300

Query: 339 EADFSGVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPF 398
           +AD SG++G  +  ISK+ HK+ V+++E+GTEA AA+  ++    L  M + +   + PF
Sbjct: 301 KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCML--MPEENFTADHPF 358

Query: 399 LLLLWEVTTQSLLFLGKVVNP 419
           L  +   ++ S+LFLG+  +P
Sbjct: 359 LFFIRHNSSGSILFLGRFSSP 379


>gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 6 [Homo sapiens]
          Length = 376

 Score =  168 bits (426), Expect = 7e-42
 Identities = 116/371 (31%), Positives = 200/371 (53%), Gaps = 13/371 (3%)

Query: 57  FALRLYKELAADAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIH 116
           FAL L K L  D   N+FFSP+S+S  LA++ +GA+ NT+A + + L FN +     DIH
Sbjct: 11  FALNLLKTLGKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGGG-GDIH 69

Query: 117 QGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTT 176
           QGF+SLL  +     +  L++ N LF +K       + DS ++ Y A     +F  +V  
Sbjct: 70  QGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEK 129

Query: 177 GRQ-INDYLRRQTYGQVVDCLPEFSQD--TFMVLANYIFFKAKWKHPFSRYQTQKQESFF 233
            R+ IN ++  +T G++ + L   S D  T +VL N ++F+  W   F +  T+++  F 
Sbjct: 130 SRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEER-LFK 188

Query: 234 VDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLV-LPDPGK-MKQVEAAL 291
           V +     V MM ++   +  Y  ++   +L + Y G  L +++ LPD    ++ VE  L
Sbjct: 189 VSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRTVEKEL 248

Query: 292 QPQTLRKWGQLLL--PSLLDLHLPRFSISGTYNLEDILPQIGLTNILNL-EADFSGVTGQ 348
             +   +W +L +     +++ LPRF +  +Y++E +L  +G+T+   L +ADFSG++ Q
Sbjct: 249 TYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMS-Q 307

Query: 349 LNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQ 408
            + ++SKV HK+ V+++E+GTEA AA+  +        +  P    + PFL  +    T 
Sbjct: 308 TDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFV--PRFCADHPFLFFIQHSKTN 365

Query: 409 SLLFLGKVVNP 419
            +LF G+  +P
Sbjct: 366 GILFCGRFSSP 376


>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
           sapiens]
          Length = 376

 Score =  165 bits (418), Expect = 6e-41
 Identities = 116/372 (31%), Positives = 196/372 (52%), Gaps = 15/372 (4%)

Query: 57  FALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADI 115
           FA+RL K L  D P  N+F SPVSIS+ LA++ LGA+ NT+  + + L  N     E DI
Sbjct: 11  FAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSLN----TEEDI 66

Query: 116 HQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVT 175
           H+ F+SLL  +     +  L+  N LF +K  +    + +S  + Y A     +F  +  
Sbjct: 67  HRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAE 126

Query: 176 TGRQ-INDYLRRQTYGQVVDCLPEFSQD--TFMVLANYIFFKAKWKHPFSRYQTQKQESF 232
             R+ IN ++ ++T G++ + LP  S D  T +VL N I+FK KW  PF    T ++  F
Sbjct: 127 ESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYT-REMPF 185

Query: 233 FVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLV-LPDPG-KMKQVEAA 290
            +++     V MM+Q+   +  +  ++   +L++ Y    L+LLV LPD G ++  VE +
Sbjct: 186 KINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGVELSTVEKS 245

Query: 291 LQPQTLRKWGQ--LLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNL-EADFSGVTG 347
           L  + L  W +   +  + +++ LP+F +   Y++E +L  +G+ +     +AD S ++ 
Sbjct: 246 LTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAMSA 305

Query: 348 QLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTT 407
           + +  +SK  HK+ V+++E+GTEA AAS            S P    + PFL  +     
Sbjct: 306 ERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECC-MESGPRFCADHPFLFFIRHNRA 364

Query: 408 QSLLFLGKVVNP 419
            S+LF G+  +P
Sbjct: 365 NSILFCGRFSSP 376


>gi|8393956 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 13 [Homo sapiens]
          Length = 391

 Score =  165 bits (417), Expect = 8e-41
 Identities = 116/390 (29%), Positives = 194/390 (49%), Gaps = 32/390 (8%)

Query: 55  TNFALRLYKELAADAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFN-------- 106
           T     L+KEL     GNIFFSPV I T + ++ LG +  T++ + E             
Sbjct: 9   TRLGFDLFKELKKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRI 68

Query: 107 ------LTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKEL 160
                 + E  EA +HQ F+  L  ++  +   EL + N LF +K     Q YLD +++ 
Sbjct: 69  KAEEKEVIENTEA-VHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVEKY 127

Query: 161 YGAFAFSANFTDSVTTGRQ-INDYLRRQTYGQVVDCLPE--FSQDTFMVLANYIFFKAKW 217
           Y A     +F ++    R+ IN ++  +T  ++ D  P+   S  T +VL N ++FK +W
Sbjct: 128 YHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQW 187

Query: 218 KHPFSRYQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLV 277
              F +  T K+E F++++ TS  V MM Q     F + +DL   +L I Y+ N L++ V
Sbjct: 188 DREFKKENT-KEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFV 246

Query: 278 L--PDPGKMKQVEAALQPQTLRKWGQ--LLLPSLLDLHLPRFSISGTYNLEDILPQIGLT 333
           L   D   ++++   + P+ L +W     +    ++LHLPRF +   Y+LE +L  +G+ 
Sbjct: 247 LLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVLAAMGMG 306

Query: 334 NILN-LEADFSGVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDP-- 390
           +  +  +AD+SG++        K  H + V ++E+GTEA AA+G+          S P  
Sbjct: 307 DAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGI-----GFTVTSAPGH 361

Query: 391 -HAHFNRPFLLLLWEVTTQSLLFLGKVVNP 419
            + H N PFL  +    + S+LF G+  +P
Sbjct: 362 ENVHCNHPFLFFIRHNESNSILFFGRFSSP 391


>gi|154759291 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 10 [Homo
           sapiens]
          Length = 444

 Score =  162 bits (410), Expect = 5e-40
 Identities = 107/369 (28%), Positives = 192/369 (52%), Gaps = 11/369 (2%)

Query: 55  TNFALRLYKELAADAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFN-LTETPEA 113
           +NF   L ++++    GN+ FSP  +S  +  L LGA   T   I  GL    L  T   
Sbjct: 80  SNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPG 139

Query: 114 DIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDS 173
            +   F+ L  TL+  + +L L  G+  F+ K    ++ + +  K  +       NF ++
Sbjct: 140 LLPSLFKGLRETLSR-NLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNA 198

Query: 174 VTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFF 233
               R +N Y+ ++T G++     E + +T ++L +YI FK KW  PF    T+  ++F 
Sbjct: 199 SQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE-VDTFH 257

Query: 234 VDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDP-GKMKQVEAALQ 292
           +D+  +++VPMM+        +D++  C VL++ Y+GNA  L+VL +  G    +E  L 
Sbjct: 258 LDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLT 317

Query: 293 PQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS--GVTGQLN 350
              +  W + +    +++  P+F +   Y + ++L Q+G+  I +  AD S    TG+ N
Sbjct: 318 TDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGR-N 376

Query: 351 KTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSL 410
             +S+V  + ++++ E+GTE  A +G+LS+  + +    P    +RPF  +++E T+  L
Sbjct: 377 LQVSRVLQRTVIEVDERGTE--AVAGILSEITAYS--MPPVIKVDRPFHFMIYEETSGML 432

Query: 411 LFLGKVVNP 419
           LFLG+VVNP
Sbjct: 433 LFLGRVVNP 441


>gi|7705879 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 10 [Homo
           sapiens]
          Length = 444

 Score =  162 bits (410), Expect = 5e-40
 Identities = 107/369 (28%), Positives = 192/369 (52%), Gaps = 11/369 (2%)

Query: 55  TNFALRLYKELAADAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFN-LTETPEA 113
           +NF   L ++++    GN+ FSP  +S  +  L LGA   T   I  GL    L  T   
Sbjct: 80  SNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPG 139

Query: 114 DIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDS 173
            +   F+ L  TL+  + +L L  G+  F+ K    ++ + +  K  +       NF ++
Sbjct: 140 LLPSLFKGLRETLSR-NLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNA 198

Query: 174 VTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFF 233
               R +N Y+ ++T G++     E + +T ++L +YI FK KW  PF    T+  ++F 
Sbjct: 199 SQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE-VDTFH 257

Query: 234 VDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDP-GKMKQVEAALQ 292
           +D+  +++VPMM+        +D++  C VL++ Y+GNA  L+VL +  G    +E  L 
Sbjct: 258 LDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLT 317

Query: 293 PQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS--GVTGQLN 350
              +  W + +    +++  P+F +   Y + ++L Q+G+  I +  AD S    TG+ N
Sbjct: 318 TDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGR-N 376

Query: 351 KTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSL 410
             +S+V  + ++++ E+GTE  A +G+LS+  + +    P    +RPF  +++E T+  L
Sbjct: 377 LQVSRVLQRTVIEVDERGTE--AVAGILSEITAYS--MPPVIKVDRPFHFMIYEETSGML 432

Query: 411 LFLGKVVNP 419
           LFLG+VVNP
Sbjct: 433 LFLGRVVNP 441


>gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo
           sapiens]
          Length = 464

 Score =  160 bits (405), Expect = 2e-39
 Identities = 122/379 (32%), Positives = 204/379 (53%), Gaps = 19/379 (5%)

Query: 55  TNFALRLYKELA--ADAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFN-LTETP 111
           + FA   Y+ LA   +   NIF SP+SIST  A+  LGA  +T   ++E   F+ ++E  
Sbjct: 88  SRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKT 147

Query: 112 EADIHQGFRSL---LHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSA 168
              IH  F  L   L+  A  S KL     N LF DK L   + Y D  + +YGA     
Sbjct: 148 SDQIHFFFAKLNCRLYRKANKSSKLVS--ANRLFGDKSLTFNETYQDISELVYGAKLQPL 205

Query: 169 NFTDSVTTGRQ-INDYLRRQTYGQVVDCLPE--FSQDTFMVLANYIFFKAKWKHPFSRYQ 225
           +F ++    R  IN ++  +T G++ D +P    ++ T +VL N I+FK  WK  FS   
Sbjct: 206 DFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFSPEN 265

Query: 226 TQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALAL-LVLPDPGK- 283
           T+K E F+  +  S    MM+Q+   R+    +    VL++ ++G+ + + L+LP P K 
Sbjct: 266 TRK-ELFYKADGESCSASMMYQEGKFRYRRVAE-GTQVLELPFKGDDITMVLILPKPEKS 323

Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLE-ADF 342
           + +VE  L P+ L++W   L   +L +H+PRF I   ++L++ L  +GL ++ + E +  
Sbjct: 324 LAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKL 383

Query: 343 SGVT--GQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLL 400
            G+   G+ +  +S   HKA ++++E+G+EA A++ ++    SLN  +      NRPFL+
Sbjct: 384 PGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNP-NRVTFKANRPFLV 442

Query: 401 LLWEVTTQSLLFLGKVVNP 419
            + EV   +++F+G+V NP
Sbjct: 443 FIREVPLNTIIFMGRVANP 461


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,465,377
Number of Sequences: 37866
Number of extensions: 743174
Number of successful extensions: 2223
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1936
Number of HSP's gapped (non-prelim): 69
length of query: 422
length of database: 18,247,518
effective HSP length: 105
effective length of query: 317
effective length of database: 14,271,588
effective search space: 4524093396
effective search space used: 4524093396
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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