BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|122937297 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 [Homo sapiens] (422 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|122937297 serpin peptidase inhibitor, clade A (alpha-1 antipr... 848 0.0 gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ... 341 8e-94 gi|21361302 serine (or cysteine) proteinase inhibitor, clade A (... 333 1e-91 gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,... 328 4e-90 gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur... 314 8e-86 gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom... 313 1e-85 gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom... 313 1e-85 gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom... 313 1e-85 gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom... 313 1e-85 gi|189163534 serine proteinase inhibitor, clade A, member 1 [Hom... 313 1e-85 gi|189163532 serine proteinase inhibitor, clade A, member 1 [Hom... 313 1e-85 gi|189163530 serine proteinase inhibitor, clade A, member 1 [Hom... 313 1e-85 gi|189163528 serine proteinase inhibitor, clade A, member 1 [Hom... 313 1e-85 gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo... 313 1e-85 gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo... 313 1e-85 gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo... 313 1e-85 gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ... 304 9e-83 gi|73858564 corticosteroid binding globulin precursor [Homo sapi... 287 1e-77 gi|27777657 serine (or cysteine) proteinase inhibitor, clade A (... 269 3e-72 gi|110225349 serine (or cysteine) proteinase inhibitor, clade A ... 216 3e-56 gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o... 199 4e-51 gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (... 199 5e-51 gi|4826902 serine (or cysteine) proteinase inhibitor, clade B (o... 185 6e-47 gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (... 175 8e-44 gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (... 168 7e-42 gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s... 165 6e-41 gi|8393956 serine (or cysteine) proteinase inhibitor, clade B (o... 165 8e-41 gi|154759291 serine (or cysteine) proteinase inhibitor, clade A ... 162 5e-40 gi|7705879 serine (or cysteine) proteinase inhibitor, clade A (a... 162 5e-40 gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s... 160 2e-39 >gi|122937297 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 [Homo sapiens] Length = 422 Score = 848 bits (2191), Expect = 0.0 Identities = 422/422 (100%), Positives = 422/422 (100%) Query: 1 MGPAWLWLLGTGILASVHCQPLLAHGDKSLQGPQPPRHQLSEPAPAYHRITPTITNFALR 60 MGPAWLWLLGTGILASVHCQPLLAHGDKSLQGPQPPRHQLSEPAPAYHRITPTITNFALR Sbjct: 1 MGPAWLWLLGTGILASVHCQPLLAHGDKSLQGPQPPRHQLSEPAPAYHRITPTITNFALR 60 Query: 61 LYKELAADAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFR 120 LYKELAADAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFR Sbjct: 61 LYKELAADAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFR 120 Query: 121 SLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQI 180 SLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQI Sbjct: 121 SLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQI 180 Query: 181 NDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSL 240 NDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSL Sbjct: 181 NDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSL 240 Query: 241 QVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRKWG 300 QVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRKWG Sbjct: 241 QVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRKWG 300 Query: 301 QLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSHKA 360 QLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSHKA Sbjct: 301 QLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSHKA 360 Query: 361 MVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVNPV 420 MVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVNPV Sbjct: 361 MVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVNPV 420 Query: 421 AG 422 AG Sbjct: 421 AG 422 >gi|110225347 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 isoform A [Homo sapiens] Length = 435 Score = 341 bits (874), Expect = 8e-94 Identities = 185/411 (45%), Positives = 265/411 (64%), Gaps = 6/411 (1%) Query: 12 GILASVH-CQPLLAHGDKSLQGPQP-PRHQLSEPAPAYHRITPTITNFALRLYKELAADA 69 G+L +V C P+ + P P S PA + + T+FA RLY+ L + Sbjct: 25 GVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPASQVYSLN---TDFAFRLYRRLVLET 81 Query: 70 PG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFRSLLHTLAL 128 P NIFFSPVS+ST+LA+LSLGA + T IL+GLGFNLT TPE+ IHQGF+ L+H+L + Sbjct: 82 PSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQHLVHSLTV 141 Query: 129 PSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQINDYLRRQT 188 PS L LK+G++LF+ K L+ + ++L ++K LY A FS +F++ +IN +++++T Sbjct: 142 PSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARINSHVKKKT 201 Query: 189 YGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQVPMMHQK 248 G+VVD + T MVL N+IFFKAKW+ PF T+K F V E+ ++ VPMMHQK Sbjct: 202 QGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQK 261 Query: 249 EMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRKWGQLLLPSLL 308 E F D +L C VLQ++Y+G+A+A VLP GKM+Q+E AL +TLRKW L + Sbjct: 262 EQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSHSLQKRWI 321 Query: 309 DLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSHKAMVDMSEKG 368 ++ +PRFSIS +YNLE ILP++G+ N+ + ADFSG+ + + +SK +HKA++D+SE+G Sbjct: 322 EVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVSEEG 381 Query: 369 TEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVNP 419 TEA AA+ S + S FNR FL+++ T +LFLGKV NP Sbjct: 382 TEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENP 432 >gi|21361302 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 [Homo sapiens] Length = 427 Score = 333 bits (855), Expect = 1e-91 Identities = 187/422 (44%), Positives = 275/422 (65%), Gaps = 10/422 (2%) Query: 5 WLWLLGTGILASVHCQPLLAHGDKSLQGPQPPRH-QLSEPAPAYHRITPTITNFALRLYK 63 +L LL G+LA H Q + H +S + + E +P+ +I P +FA R Y Sbjct: 6 YLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSL-KIAPANADFAFRFYY 64 Query: 64 ELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFRSL 122 +A++ PG NIFFSP+SIS A+LSLGA +++ + ILEGLGFNLTE E+D+H+GF+ L Sbjct: 65 LIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHL 124 Query: 123 LHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQIND 182 LHTL LP LE +VG++LFL LK +L+ +Y A F NF D+V T + IND Sbjct: 125 LHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLIND 184 Query: 183 YLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQV 242 +++++T G++VD + E +D MVL NYI+FKA W+ PF +T ++ F+VDE T+++V Sbjct: 185 HVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKD-FYVDENTTVRV 243 Query: 243 PMMHQ-KEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRKWGQ 301 PMM Q +E H +L+D+ L C+VL+++Y+G+A +LP+ GKM+++E L P+ L +W Sbjct: 244 PMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMRWNN 303 Query: 302 LL----LPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVS 357 LL L+LHLP+FSISG+Y L+ ILP++G T++ + AD SG+T Q SK Sbjct: 304 LLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSF 363 Query: 358 HKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVV 417 HKA +D+ E GTEA AA+ + S T + FNRPFL++++ +TQS+LFLGKVV Sbjct: 364 HKATLDVDEAGTEAAAATSFAIKFFSAQT-NRHILRFNRPFLVVIFSTSTQSVLFLGKVV 422 Query: 418 NP 419 +P Sbjct: 423 DP 424 >gi|205277441 serine (or cysteine) proteinase inhibitor, clade A, member 7 [Homo sapiens] Length = 415 Score = 328 bits (842), Expect = 4e-90 Identities = 180/417 (43%), Positives = 260/417 (62%), Gaps = 12/417 (2%) Query: 5 WLWLLGTGILASVHCQPLLAHGDKSLQGPQPPRHQLSEPAPAYHRITPTITNFALRLYKE 64 +L LL G+ A++HC S +G H S+P ++++ +FA LY+ Sbjct: 6 YLVLLVLGLHATIHCA--------SPEGKVTACHS-SQPNATLYKMSSINADFAFNLYRR 56 Query: 65 LAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFRSLL 123 + P NIFFSPVSIS L +LS GA +T I+E LGFNLT+TP +I GF+ L+ Sbjct: 57 FTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLI 116 Query: 124 HTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQINDY 183 +L P +LEL++GN+LF+ K LKP +L+ +K LY FS +F++ ++IN + Sbjct: 117 CSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSH 176 Query: 184 LRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQVP 243 + QT G+VV + + +T MVL NYI FKA+W +PF +T+ SF +D+ T++QVP Sbjct: 177 VEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVP 236 Query: 244 MMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRKWGQLL 303 MMHQ E + L D +L CTVLQ++Y NALAL VLP G+M+ VEAA+ +TL+KW +LL Sbjct: 237 MMHQMEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLL 296 Query: 304 LPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSHKAMVD 363 +DL +P+FSIS TY+L L ++G+ + + ADFSG+T +S +HKA++ Sbjct: 297 QKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLH 356 Query: 364 MSEKGTEAGAASGL-LSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVNP 419 + EKGTEA A + LS P NT P +R F+LL+ E +T+S+LFLGKVVNP Sbjct: 357 IGEKGTEAAAVPEVELSDQPE-NTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNP 412 >gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor [Homo sapiens] Length = 423 Score = 314 bits (805), Expect = 8e-86 Identities = 172/415 (41%), Positives = 249/415 (60%), Gaps = 4/415 (0%) Query: 8 LLGTGILASVHCQPLLAHGDKSLQGPQPPRHQLSEPAPAYHRITPTITNFALRLYKELAA 67 LL G+LA+ C +L H + L + + +FA LYK+L Sbjct: 7 LLALGLLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSLYKQLVL 66 Query: 68 DAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFRSLLHTL 126 AP N+ FSP+SIST LA LSLGA T IL+GL FNLTET EA+IHQ F+ LL TL Sbjct: 67 KAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTL 126 Query: 127 ALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQINDYLRR 186 S +L+L +GN++F+ ++L + + K LYG+ AF+ +F DS + INDY++ Sbjct: 127 NQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKN 186 Query: 187 QTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQVPMMH 246 T G++ D + + T MVL NYIFFKAKW+ PF T Q F++ ++ + VPMM Sbjct: 187 GTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTH-QSRFYLSKKKWVMVPMMS 245 Query: 247 QKEMH-RFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRKW-GQLLL 304 + + D++L+CTV++++Y GNA AL +LPD KM++VEA L P+TL++W L Sbjct: 246 LHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEF 305 Query: 305 PSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSHKAMVDM 364 + +L+LP+FSIS YNL DIL Q+G+ +AD SG+TG N +S+V HKA++D+ Sbjct: 306 REIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDV 365 Query: 365 SEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVNP 419 E+GTEA AA+ + S + FNRPFL+++ TQ++ F+ KV NP Sbjct: 366 FEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNP 420 >gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 313 bits (803), Expect = 1e-85 Identities = 169/376 (44%), Positives = 240/376 (63%), Gaps = 6/376 (1%) Query: 45 PAYHRITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGL 103 P +++ITP + FA LY++LA + NIFFSPVSI+T A+LSLG +A+T ILEGL Sbjct: 45 PTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGL 104 Query: 104 GFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGA 163 FNLTE PEA IH+GF+ LL TL P +L+L GN LFL + LK +L+ +K+LY + Sbjct: 105 NFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164 Query: 164 FAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSR 223 AF+ NF D+ +QINDY+ + T G++VD + E +DT L NYIFFK KW+ PF Sbjct: 165 EAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEV 224 Query: 224 YQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGK 283 T+ +E F VD+ T+++VPMM + M + + L+ VL ++Y GNA A+ LPD GK Sbjct: 225 KDTE-EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGK 283 Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS 343 ++ +E L + K+ + LHLP+ SI+GTY+L+ +L Q+G+T + + AD S Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343 Query: 344 GVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLW 403 GVT + +SK HKA++ + EKGTEA A L + P S+ P FN+PF+ L+ Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSI----PPEVKFNKPFVFLMI 399 Query: 404 EVTTQSLLFLGKVVNP 419 E T+S LF+GKVVNP Sbjct: 400 EQNTKSPLFMGKVVNP 415 >gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 313 bits (803), Expect = 1e-85 Identities = 169/376 (44%), Positives = 240/376 (63%), Gaps = 6/376 (1%) Query: 45 PAYHRITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGL 103 P +++ITP + FA LY++LA + NIFFSPVSI+T A+LSLG +A+T ILEGL Sbjct: 45 PTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGL 104 Query: 104 GFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGA 163 FNLTE PEA IH+GF+ LL TL P +L+L GN LFL + LK +L+ +K+LY + Sbjct: 105 NFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164 Query: 164 FAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSR 223 AF+ NF D+ +QINDY+ + T G++VD + E +DT L NYIFFK KW+ PF Sbjct: 165 EAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEV 224 Query: 224 YQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGK 283 T+ +E F VD+ T+++VPMM + M + + L+ VL ++Y GNA A+ LPD GK Sbjct: 225 KDTE-EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGK 283 Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS 343 ++ +E L + K+ + LHLP+ SI+GTY+L+ +L Q+G+T + + AD S Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343 Query: 344 GVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLW 403 GVT + +SK HKA++ + EKGTEA A L + P S+ P FN+PF+ L+ Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSI----PPEVKFNKPFVFLMI 399 Query: 404 EVTTQSLLFLGKVVNP 419 E T+S LF+GKVVNP Sbjct: 400 EQNTKSPLFMGKVVNP 415 >gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 313 bits (803), Expect = 1e-85 Identities = 169/376 (44%), Positives = 240/376 (63%), Gaps = 6/376 (1%) Query: 45 PAYHRITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGL 103 P +++ITP + FA LY++LA + NIFFSPVSI+T A+LSLG +A+T ILEGL Sbjct: 45 PTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGL 104 Query: 104 GFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGA 163 FNLTE PEA IH+GF+ LL TL P +L+L GN LFL + LK +L+ +K+LY + Sbjct: 105 NFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164 Query: 164 FAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSR 223 AF+ NF D+ +QINDY+ + T G++VD + E +DT L NYIFFK KW+ PF Sbjct: 165 EAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEV 224 Query: 224 YQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGK 283 T+ +E F VD+ T+++VPMM + M + + L+ VL ++Y GNA A+ LPD GK Sbjct: 225 KDTE-EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGK 283 Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS 343 ++ +E L + K+ + LHLP+ SI+GTY+L+ +L Q+G+T + + AD S Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343 Query: 344 GVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLW 403 GVT + +SK HKA++ + EKGTEA A L + P S+ P FN+PF+ L+ Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSI----PPEVKFNKPFVFLMI 399 Query: 404 EVTTQSLLFLGKVVNP 419 E T+S LF+GKVVNP Sbjct: 400 EQNTKSPLFMGKVVNP 415 >gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 313 bits (803), Expect = 1e-85 Identities = 169/376 (44%), Positives = 240/376 (63%), Gaps = 6/376 (1%) Query: 45 PAYHRITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGL 103 P +++ITP + FA LY++LA + NIFFSPVSI+T A+LSLG +A+T ILEGL Sbjct: 45 PTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGL 104 Query: 104 GFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGA 163 FNLTE PEA IH+GF+ LL TL P +L+L GN LFL + LK +L+ +K+LY + Sbjct: 105 NFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164 Query: 164 FAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSR 223 AF+ NF D+ +QINDY+ + T G++VD + E +DT L NYIFFK KW+ PF Sbjct: 165 EAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEV 224 Query: 224 YQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGK 283 T+ +E F VD+ T+++VPMM + M + + L+ VL ++Y GNA A+ LPD GK Sbjct: 225 KDTE-EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGK 283 Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS 343 ++ +E L + K+ + LHLP+ SI+GTY+L+ +L Q+G+T + + AD S Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343 Query: 344 GVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLW 403 GVT + +SK HKA++ + EKGTEA A L + P S+ P FN+PF+ L+ Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSI----PPEVKFNKPFVFLMI 399 Query: 404 EVTTQSLLFLGKVVNP 419 E T+S LF+GKVVNP Sbjct: 400 EQNTKSPLFMGKVVNP 415 >gi|189163534 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 313 bits (803), Expect = 1e-85 Identities = 169/376 (44%), Positives = 240/376 (63%), Gaps = 6/376 (1%) Query: 45 PAYHRITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGL 103 P +++ITP + FA LY++LA + NIFFSPVSI+T A+LSLG +A+T ILEGL Sbjct: 45 PTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGL 104 Query: 104 GFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGA 163 FNLTE PEA IH+GF+ LL TL P +L+L GN LFL + LK +L+ +K+LY + Sbjct: 105 NFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164 Query: 164 FAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSR 223 AF+ NF D+ +QINDY+ + T G++VD + E +DT L NYIFFK KW+ PF Sbjct: 165 EAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEV 224 Query: 224 YQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGK 283 T+ +E F VD+ T+++VPMM + M + + L+ VL ++Y GNA A+ LPD GK Sbjct: 225 KDTE-EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGK 283 Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS 343 ++ +E L + K+ + LHLP+ SI+GTY+L+ +L Q+G+T + + AD S Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343 Query: 344 GVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLW 403 GVT + +SK HKA++ + EKGTEA A L + P S+ P FN+PF+ L+ Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSI----PPEVKFNKPFVFLMI 399 Query: 404 EVTTQSLLFLGKVVNP 419 E T+S LF+GKVVNP Sbjct: 400 EQNTKSPLFMGKVVNP 415 >gi|189163532 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 313 bits (803), Expect = 1e-85 Identities = 169/376 (44%), Positives = 240/376 (63%), Gaps = 6/376 (1%) Query: 45 PAYHRITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGL 103 P +++ITP + FA LY++LA + NIFFSPVSI+T A+LSLG +A+T ILEGL Sbjct: 45 PTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGL 104 Query: 104 GFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGA 163 FNLTE PEA IH+GF+ LL TL P +L+L GN LFL + LK +L+ +K+LY + Sbjct: 105 NFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164 Query: 164 FAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSR 223 AF+ NF D+ +QINDY+ + T G++VD + E +DT L NYIFFK KW+ PF Sbjct: 165 EAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEV 224 Query: 224 YQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGK 283 T+ +E F VD+ T+++VPMM + M + + L+ VL ++Y GNA A+ LPD GK Sbjct: 225 KDTE-EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGK 283 Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS 343 ++ +E L + K+ + LHLP+ SI+GTY+L+ +L Q+G+T + + AD S Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343 Query: 344 GVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLW 403 GVT + +SK HKA++ + EKGTEA A L + P S+ P FN+PF+ L+ Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSI----PPEVKFNKPFVFLMI 399 Query: 404 EVTTQSLLFLGKVVNP 419 E T+S LF+GKVVNP Sbjct: 400 EQNTKSPLFMGKVVNP 415 >gi|189163530 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 313 bits (803), Expect = 1e-85 Identities = 169/376 (44%), Positives = 240/376 (63%), Gaps = 6/376 (1%) Query: 45 PAYHRITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGL 103 P +++ITP + FA LY++LA + NIFFSPVSI+T A+LSLG +A+T ILEGL Sbjct: 45 PTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGL 104 Query: 104 GFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGA 163 FNLTE PEA IH+GF+ LL TL P +L+L GN LFL + LK +L+ +K+LY + Sbjct: 105 NFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164 Query: 164 FAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSR 223 AF+ NF D+ +QINDY+ + T G++VD + E +DT L NYIFFK KW+ PF Sbjct: 165 EAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEV 224 Query: 224 YQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGK 283 T+ +E F VD+ T+++VPMM + M + + L+ VL ++Y GNA A+ LPD GK Sbjct: 225 KDTE-EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGK 283 Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS 343 ++ +E L + K+ + LHLP+ SI+GTY+L+ +L Q+G+T + + AD S Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343 Query: 344 GVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLW 403 GVT + +SK HKA++ + EKGTEA A L + P S+ P FN+PF+ L+ Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSI----PPEVKFNKPFVFLMI 399 Query: 404 EVTTQSLLFLGKVVNP 419 E T+S LF+GKVVNP Sbjct: 400 EQNTKSPLFMGKVVNP 415 >gi|189163528 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 313 bits (803), Expect = 1e-85 Identities = 169/376 (44%), Positives = 240/376 (63%), Gaps = 6/376 (1%) Query: 45 PAYHRITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGL 103 P +++ITP + FA LY++LA + NIFFSPVSI+T A+LSLG +A+T ILEGL Sbjct: 45 PTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGL 104 Query: 104 GFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGA 163 FNLTE PEA IH+GF+ LL TL P +L+L GN LFL + LK +L+ +K+LY + Sbjct: 105 NFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164 Query: 164 FAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSR 223 AF+ NF D+ +QINDY+ + T G++VD + E +DT L NYIFFK KW+ PF Sbjct: 165 EAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEV 224 Query: 224 YQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGK 283 T+ +E F VD+ T+++VPMM + M + + L+ VL ++Y GNA A+ LPD GK Sbjct: 225 KDTE-EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGK 283 Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS 343 ++ +E L + K+ + LHLP+ SI+GTY+L+ +L Q+G+T + + AD S Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343 Query: 344 GVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLW 403 GVT + +SK HKA++ + EKGTEA A L + P S+ P FN+PF+ L+ Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSI----PPEVKFNKPFVFLMI 399 Query: 404 EVTTQSLLFLGKVVNP 419 E T+S LF+GKVVNP Sbjct: 400 EQNTKSPLFMGKVVNP 415 >gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 313 bits (803), Expect = 1e-85 Identities = 169/376 (44%), Positives = 240/376 (63%), Gaps = 6/376 (1%) Query: 45 PAYHRITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGL 103 P +++ITP + FA LY++LA + NIFFSPVSI+T A+LSLG +A+T ILEGL Sbjct: 45 PTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGL 104 Query: 104 GFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGA 163 FNLTE PEA IH+GF+ LL TL P +L+L GN LFL + LK +L+ +K+LY + Sbjct: 105 NFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164 Query: 164 FAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSR 223 AF+ NF D+ +QINDY+ + T G++VD + E +DT L NYIFFK KW+ PF Sbjct: 165 EAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEV 224 Query: 224 YQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGK 283 T+ +E F VD+ T+++VPMM + M + + L+ VL ++Y GNA A+ LPD GK Sbjct: 225 KDTE-EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGK 283 Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS 343 ++ +E L + K+ + LHLP+ SI+GTY+L+ +L Q+G+T + + AD S Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343 Query: 344 GVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLW 403 GVT + +SK HKA++ + EKGTEA A L + P S+ P FN+PF+ L+ Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSI----PPEVKFNKPFVFLMI 399 Query: 404 EVTTQSLLFLGKVVNP 419 E T+S LF+GKVVNP Sbjct: 400 EQNTKSPLFMGKVVNP 415 >gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 313 bits (803), Expect = 1e-85 Identities = 169/376 (44%), Positives = 240/376 (63%), Gaps = 6/376 (1%) Query: 45 PAYHRITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGL 103 P +++ITP + FA LY++LA + NIFFSPVSI+T A+LSLG +A+T ILEGL Sbjct: 45 PTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGL 104 Query: 104 GFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGA 163 FNLTE PEA IH+GF+ LL TL P +L+L GN LFL + LK +L+ +K+LY + Sbjct: 105 NFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164 Query: 164 FAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSR 223 AF+ NF D+ +QINDY+ + T G++VD + E +DT L NYIFFK KW+ PF Sbjct: 165 EAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEV 224 Query: 224 YQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGK 283 T+ +E F VD+ T+++VPMM + M + + L+ VL ++Y GNA A+ LPD GK Sbjct: 225 KDTE-EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGK 283 Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS 343 ++ +E L + K+ + LHLP+ SI+GTY+L+ +L Q+G+T + + AD S Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343 Query: 344 GVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLW 403 GVT + +SK HKA++ + EKGTEA A L + P S+ P FN+PF+ L+ Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSI----PPEVKFNKPFVFLMI 399 Query: 404 EVTTQSLLFLGKVVNP 419 E T+S LF+GKVVNP Sbjct: 400 EQNTKSPLFMGKVVNP 415 >gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 313 bits (803), Expect = 1e-85 Identities = 169/376 (44%), Positives = 240/376 (63%), Gaps = 6/376 (1%) Query: 45 PAYHRITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGL 103 P +++ITP + FA LY++LA + NIFFSPVSI+T A+LSLG +A+T ILEGL Sbjct: 45 PTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGL 104 Query: 104 GFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGA 163 FNLTE PEA IH+GF+ LL TL P +L+L GN LFL + LK +L+ +K+LY + Sbjct: 105 NFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164 Query: 164 FAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSR 223 AF+ NF D+ +QINDY+ + T G++VD + E +DT L NYIFFK KW+ PF Sbjct: 165 EAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEV 224 Query: 224 YQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGK 283 T+ +E F VD+ T+++VPMM + M + + L+ VL ++Y GNA A+ LPD GK Sbjct: 225 KDTE-EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGK 283 Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS 343 ++ +E L + K+ + LHLP+ SI+GTY+L+ +L Q+G+T + + AD S Sbjct: 284 LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 343 Query: 344 GVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLW 403 GVT + +SK HKA++ + EKGTEA A L + P S+ P FN+PF+ L+ Sbjct: 344 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSI----PPEVKFNKPFVFLMI 399 Query: 404 EVTTQSLLFLGKVVNP 419 E T+S LF+GKVVNP Sbjct: 400 EQNTKSPLFMGKVVNP 415 >gi|194018472 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 [Homo sapiens] Length = 406 Score = 304 bits (779), Expect = 9e-83 Identities = 168/415 (40%), Positives = 255/415 (61%), Gaps = 12/415 (2%) Query: 6 LWLLGTGILASVHCQPLLAHGDKSLQGPQPPRHQLSEPAPAYHRITPTITNFALRLYKEL 65 L+LL +L S L H + ++ H + AP+ R +F LY+ L Sbjct: 3 LFLLLCLVLLSPQGASLHRHHPREMKKRVEDLHVGATVAPSSRR------DFTFDLYRAL 56 Query: 66 AADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFRSLLH 124 A+ AP +IFFSPVSIS +LA+LSLGA ++T ILEGLG NL ++ E ++H+GF+ LL Sbjct: 57 ASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQ 116 Query: 125 TLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQINDYL 184 L P +L +GN+LF D + + ++ ++K LY A F NF DS +QINDY+ Sbjct: 117 ELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYV 176 Query: 185 RRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQVPM 244 +QT G++VD L + +++ NYIFFKAKW+ F+ TQ+Q+ F+V T ++VPM Sbjct: 177 AKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQD-FYVTSETVVRVPM 235 Query: 245 MHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRKWGQLLL 304 M +++ + +L D++L+C V+ + Y+GNA AL +LP GKM+QVE L +TLRKW ++ Sbjct: 236 MSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFK 295 Query: 305 PSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSHKAMVDM 364 L+L+LP+FSI G+Y LE +LP +G++N+ AD SG++ N +S++ HKA+V++ Sbjct: 296 KRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEV 355 Query: 365 SEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVNP 419 E GT A AA+G + S ++ FNRPFL+ + ++LFLGKV P Sbjct: 356 DESGTRAAAATGTIFTFRSAR-LNSQRLVFNRPFLMF---IVDNNILFLGKVNRP 406 >gi|73858564 corticosteroid binding globulin precursor [Homo sapiens] Length = 405 Score = 287 bits (734), Expect = 1e-77 Identities = 159/391 (40%), Positives = 232/391 (59%), Gaps = 15/391 (3%) Query: 39 QLSEPAPAY------HR-ITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLG 90 Q +P AY HR + +FA LYK L A +P NIF SPVSIS LA+LSLG Sbjct: 21 QAMDPNAAYVNMSNHHRGLASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLG 80 Query: 91 AQANTSALILEGLGFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPR 150 +T A +L+GLGFNLTE E +IHQGF+ L A LE+ +GN+LFLD L+ Sbjct: 81 TCGHTRAQLLQGLGFNLTERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELL 140 Query: 151 QHYLDSIKELYGAFAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANY 210 + + IK Y + + NF D T RQIN Y++ +T G++VD +VL NY Sbjct: 141 ESFSADIKHYYESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNY 200 Query: 211 IFFKAKWKHPFSRYQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRG 270 IFFK W PF T ++E+F+VDE T ++VPMM Q +L+D +L C ++Q+ Y G Sbjct: 201 IFFKGTWTQPFDLAST-REENFYVDETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVG 259 Query: 271 NALALLVLPDPGKMKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQI 330 N +LPD GKM V AAL T+ +W L S +DL++P+ +ISG Y+L D+L ++ Sbjct: 260 NGTVFFILPDKGKMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEM 319 Query: 331 GLTNILNLEADFSGVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDP 390 G+ ++ +A+FS +T SKV HKA++ ++E+G + ++G+ +LN S P Sbjct: 320 GIADLFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGV-----TLNLTSKP 374 Query: 391 -HAHFNRPFLLLLWEVTTQSLLFLGKVVNPV 420 FN+PF++++++ T S LFL +V+NPV Sbjct: 375 IILRFNQPFIIMIFDHFTWSSLFLARVMNPV 405 >gi|27777657 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 [Homo sapiens] Length = 414 Score = 269 bits (688), Expect = 3e-72 Identities = 139/367 (37%), Positives = 225/367 (61%), Gaps = 10/367 (2%) Query: 56 NFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEAD 114 + +L K+LA PG NIF SP+SIST ++L LGAQ +T I +G FN + PE D Sbjct: 54 DLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQG--FNFRKMPEKD 111 Query: 115 IHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSV 174 +H+GF ++H L + L+L +GN+LF+D+RL+P++ +L+ K Y A NF + Sbjct: 112 LHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLE 171 Query: 175 TTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFV 234 +QIND++ ++T+G++ + + T M+LANYIFF+A+WKH F T K+E FF+ Sbjct: 172 MAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVT-KEEDFFL 230 Query: 235 DERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQ 294 ++ +S++VPMM + +++ YD L+CT+L+I Y+ N A+ +LPD GK+K +E LQ Sbjct: 231 EKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVD 290 Query: 295 TLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTIS 354 T +W LL ++D+ +PR ++GT++L+ L IG++ I D + + + + Sbjct: 291 TFSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVG 350 Query: 355 KVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDP-HAHFNRPFLLLLWEVTTQSLLFL 413 + HKA + M E+GTE A +G + P M P ++P+LLL++ S+LFL Sbjct: 351 EAVHKAELKMDERGTEGAAGTGAQTLP-----METPLVVKIDKPYLLLIYSEKIPSVLFL 405 Query: 414 GKVVNPV 420 GK+VNP+ Sbjct: 406 GKIVNPI 412 >gi|110225349 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 isoform B [Homo sapiens] Length = 335 Score = 216 bits (550), Expect = 3e-56 Identities = 111/241 (46%), Positives = 159/241 (65%) Query: 179 QINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERT 238 +IN +++++T G+VVD + T MVL N+IFFKAKW+ PF T+K F V E+ Sbjct: 92 RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151 Query: 239 SLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRK 298 ++ VPMMHQKE F D +L C VLQ++Y+G+A+A VLP GKM+Q+E AL +TLRK Sbjct: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211 Query: 299 WGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSH 358 W L +++ +PRFSIS +YNLE ILP++G+ N+ + ADFSG+ + + +SK +H Sbjct: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271 Query: 359 KAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVN 418 KA++D+SE+GTEA AA+ S + S FNR FL+++ T +LFLGKV N Sbjct: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331 Query: 419 P 419 P Sbjct: 332 P 332 Score = 35.0 bits (79), Expect = 0.13 Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 6/74 (8%) Query: 12 GILASVH-CQPLLAHGDKSLQGPQP-PRHQLSEPAPAYHRITPTITNFALRLYKELAADA 69 G+L +V C P+ + P P S PA + + T+FA RLY+ L + Sbjct: 25 GVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPASQVYSLN---TDFAFRLYRRLVLET 81 Query: 70 PG-NIFFSPVSIST 82 P NIFFSP I++ Sbjct: 82 PSQNIFFSPARINS 95 >gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3 [Homo sapiens] Length = 390 Score = 199 bits (506), Expect = 4e-51 Identities = 125/384 (32%), Positives = 210/384 (54%), Gaps = 21/384 (5%) Query: 55 TNFALRLYKELAADAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFN-LTETP-- 111 T F L+++ NIF+SP+SI++ L ++ LGA+ NT+ I + L F+ +TE Sbjct: 9 TKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVTENTTG 68 Query: 112 ---------EADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYG 162 ++H F+ LL + ELK+ N LF +K Q YLD+IK+ Y Sbjct: 69 KAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDAIKKFYQ 128 Query: 163 AFAFSANFTDSVTTGRQ-INDYLRRQTYGQVVDCLPE--FSQDTFMVLANYIFFKAKWKH 219 S +F ++ R+ IN ++ QT ++ + +PE +T +VL N I+FK +W+ Sbjct: 129 TSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYFKGQWEK 188 Query: 220 PFSRYQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVL- 278 F++ T K+E F+ ++ T + MM Q F +D+ VL+I Y+G L+++VL Sbjct: 189 KFNKEDT-KEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGKDLSMIVLL 247 Query: 279 -PDPGKMKQVEAALQPQTLRKWGQL--LLPSLLDLHLPRFSISGTYNLEDILPQIGLTNI 335 + ++++E L + L +W L + + +DLHLPRF + +Y+L+D L +G+ +I Sbjct: 248 PNEIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRTMGMVDI 307 Query: 336 LNLEADFSGVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFN 395 N +AD SG+TG +S V HKA V+++E+G EA AA+ ++ S T ++ H N Sbjct: 308 FNGDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSS-PTSTNEEFHCN 366 Query: 396 RPFLLLLWEVTTQSLLFLGKVVNP 419 PFL + + T S+LF G+ +P Sbjct: 367 HPFLFFIRQNKTNSILFYGRFSSP 390 >gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4 [Homo sapiens] Length = 390 Score = 199 bits (505), Expect = 5e-51 Identities = 126/384 (32%), Positives = 209/384 (54%), Gaps = 21/384 (5%) Query: 55 TNFALRLYKELAADAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGF-----NLTE 109 T F L+++ NIF+SP+SI++ L ++ LGA+ NT+ I + L F N TE Sbjct: 9 TKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQVTENTTE 68 Query: 110 TP-------EADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYG 162 ++H F+ LL + ELK+ N LF +K + Q YLD+IK+ Y Sbjct: 69 KAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDAIKKFYQ 128 Query: 163 AFAFSANFTDSVTTGRQ-INDYLRRQTYGQVVDCLPE--FSQDTFMVLANYIFFKAKWKH 219 S +F ++ R+ IN ++ QT ++ + P+ DT +VL N I+FK +W++ Sbjct: 129 TSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIYFKGQWEN 188 Query: 220 PFSRYQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVL- 278 F + T K+E F+ ++ T V MM Q F +D+ VL+I Y+G L+++VL Sbjct: 189 KFKKENT-KEEKFWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGKDLSMIVLL 247 Query: 279 -PDPGKMKQVEAALQPQTLRKWGQL--LLPSLLDLHLPRFSISGTYNLEDILPQIGLTNI 335 + ++++E L + L +W L + + +DLHLPRF + +Y+L+D L +G+ NI Sbjct: 248 PNEIDGLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLRTMGMVNI 307 Query: 336 LNLEADFSGVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFN 395 N +AD SG+T ++SKV HKA V+++E+G EA AA+ ++ S + ++ N Sbjct: 308 FNGDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSPSTNEEFC-CN 366 Query: 396 RPFLLLLWEVTTQSLLFLGKVVNP 419 PFL + + T S+LF G+ +P Sbjct: 367 HPFLFFIRQNKTNSILFYGRFSSP 390 >gi|4826902 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 10 [Homo sapiens] Length = 397 Score = 185 bits (470), Expect = 6e-47 Identities = 127/397 (31%), Positives = 210/397 (52%), Gaps = 30/397 (7%) Query: 50 ITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLT 108 + +I FAL L K+LA A G NIFFS SIST+L ++ LGA+ T+A + + L FN Sbjct: 4 LATSINQFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNRD 63 Query: 109 ETPEAD------------------IHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPR 150 + + D IH F++L+ + P+ LK N+++ +K Sbjct: 64 QGVKCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTYAFH 123 Query: 151 QHYLDSIKELYGAFAFSANFTDSVTTGRQ-INDYLRRQTYGQVVDCLPEFSQD--TFMVL 207 YL+ +K +GA NF ++ R+ IN ++ RQT G++ + LP+ S D T M+L Sbjct: 124 NKYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTRMIL 183 Query: 208 ANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIE 267 N ++FK W+H F Q ++ F ++E TS V MM K+ + + LQ+ Sbjct: 184 VNALYFKGIWEHQFL-VQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQLY 242 Query: 268 YRGNALALLVL--PDPGKMKQVEAALQPQTLRKWGQLLLPSLLD--LHLPRFSISGTYNL 323 Y+ L+LL+L D ++Q+E A+ + L +W + L + LHLP+F + +Y+L Sbjct: 243 YKSRDLSLLILLPEDINGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKLEDSYDL 302 Query: 324 EDILPQIGLTNILNL-EADFSGVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPP 382 + L +G+++ + +ADFSG++ N +S V HKA V+++E+GTEA A SG S+ Sbjct: 303 KSTLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGSG--SEID 360 Query: 383 SLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVNP 419 + + N PFL + T ++LF G++ +P Sbjct: 361 IRIRVPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP 397 >gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1 [Homo sapiens] Length = 379 Score = 175 bits (443), Expect = 8e-44 Identities = 124/381 (32%), Positives = 209/381 (54%), Gaps = 26/381 (6%) Query: 55 TNFALRLYKELAADAP-GNIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEA 113 T FAL L+ L+ + P GNIF SP SIS+ +A++ LG + NT+A + + FN E Sbjct: 9 TRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNTVE---- 64 Query: 114 DIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDS 173 ++H F+SL + LK+ N L+ +K +L S ++ YGA S +F + Sbjct: 65 EVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHA 124 Query: 174 VTTGRQ-INDYLRRQTYGQVVDCLPEFSQD--TFMVLANYIFFKAKWKHPFSRYQTQKQE 230 R+ IN +++ QT G++ + L D T +VL N I+FK WK F + T Sbjct: 125 SEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAP 184 Query: 231 SFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVL-PDPGK-----M 284 F ++++ V MM+QK+ + Y +DL C VL++ Y+G L++++L PD + + Sbjct: 185 -FRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDESTGL 243 Query: 285 KQVEAALQPQTLRKWGQLLLPSLLD-----LHLPRFSISGTYNLEDILPQIGLTNILNL- 338 K++E L + L +W + P LD + LPRF + +Y L L ++G+ ++ N Sbjct: 244 KKIEEQLTLEKLHEWTK---PENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS 300 Query: 339 EADFSGVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPF 398 +AD SG++G + ISK+ HK+ V+++E+GTEA AA+ ++ L M + + + PF Sbjct: 301 KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCML--MPEENFTADHPF 358 Query: 399 LLLLWEVTTQSLLFLGKVVNP 419 L + ++ S+LFLG+ +P Sbjct: 359 LFFIRHNSSGSILFLGRFSSP 379 >gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6 [Homo sapiens] Length = 376 Score = 168 bits (426), Expect = 7e-42 Identities = 116/371 (31%), Positives = 200/371 (53%), Gaps = 13/371 (3%) Query: 57 FALRLYKELAADAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIH 116 FAL L K L D N+FFSP+S+S LA++ +GA+ NT+A + + L FN + DIH Sbjct: 11 FALNLLKTLGKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGGG-GDIH 69 Query: 117 QGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTT 176 QGF+SLL + + L++ N LF +K + DS ++ Y A +F +V Sbjct: 70 QGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEK 129 Query: 177 GRQ-INDYLRRQTYGQVVDCLPEFSQD--TFMVLANYIFFKAKWKHPFSRYQTQKQESFF 233 R+ IN ++ +T G++ + L S D T +VL N ++F+ W F + T+++ F Sbjct: 130 SRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEER-LFK 188 Query: 234 VDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLV-LPDPGK-MKQVEAAL 291 V + V MM ++ + Y ++ +L + Y G L +++ LPD ++ VE L Sbjct: 189 VSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRTVEKEL 248 Query: 292 QPQTLRKWGQLLL--PSLLDLHLPRFSISGTYNLEDILPQIGLTNILNL-EADFSGVTGQ 348 + +W +L + +++ LPRF + +Y++E +L +G+T+ L +ADFSG++ Q Sbjct: 249 TYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMS-Q 307 Query: 349 LNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQ 408 + ++SKV HK+ V+++E+GTEA AA+ + + P + PFL + T Sbjct: 308 TDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFV--PRFCADHPFLFFIQHSKTN 365 Query: 409 SLLFLGKVVNP 419 +LF G+ +P Sbjct: 366 GILFCGRFSSP 376 >gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo sapiens] Length = 376 Score = 165 bits (418), Expect = 6e-41 Identities = 116/372 (31%), Positives = 196/372 (52%), Gaps = 15/372 (4%) Query: 57 FALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADI 115 FA+RL K L D P N+F SPVSIS+ LA++ LGA+ NT+ + + L N E DI Sbjct: 11 FAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSLN----TEEDI 66 Query: 116 HQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVT 175 H+ F+SLL + + L+ N LF +K + + +S + Y A +F + Sbjct: 67 HRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAE 126 Query: 176 TGRQ-INDYLRRQTYGQVVDCLPEFSQD--TFMVLANYIFFKAKWKHPFSRYQTQKQESF 232 R+ IN ++ ++T G++ + LP S D T +VL N I+FK KW PF T ++ F Sbjct: 127 ESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYT-REMPF 185 Query: 233 FVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLV-LPDPG-KMKQVEAA 290 +++ V MM+Q+ + + ++ +L++ Y L+LLV LPD G ++ VE + Sbjct: 186 KINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGVELSTVEKS 245 Query: 291 LQPQTLRKWGQ--LLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNL-EADFSGVTG 347 L + L W + + + +++ LP+F + Y++E +L +G+ + +AD S ++ Sbjct: 246 LTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAMSA 305 Query: 348 QLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTT 407 + + +SK HK+ V+++E+GTEA AAS S P + PFL + Sbjct: 306 ERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECC-MESGPRFCADHPFLFFIRHNRA 364 Query: 408 QSLLFLGKVVNP 419 S+LF G+ +P Sbjct: 365 NSILFCGRFSSP 376 >gi|8393956 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 13 [Homo sapiens] Length = 391 Score = 165 bits (417), Expect = 8e-41 Identities = 116/390 (29%), Positives = 194/390 (49%), Gaps = 32/390 (8%) Query: 55 TNFALRLYKELAADAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFN-------- 106 T L+KEL GNIFFSPV I T + ++ LG + T++ + E Sbjct: 9 TRLGFDLFKELKKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRI 68 Query: 107 ------LTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKEL 160 + E EA +HQ F+ L ++ + EL + N LF +K Q YLD +++ Sbjct: 69 KAEEKEVIENTEA-VHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVEKY 127 Query: 161 YGAFAFSANFTDSVTTGRQ-INDYLRRQTYGQVVDCLPE--FSQDTFMVLANYIFFKAKW 217 Y A +F ++ R+ IN ++ +T ++ D P+ S T +VL N ++FK +W Sbjct: 128 YHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQW 187 Query: 218 KHPFSRYQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLV 277 F + T K+E F++++ TS V MM Q F + +DL +L I Y+ N L++ V Sbjct: 188 DREFKKENT-KEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFV 246 Query: 278 L--PDPGKMKQVEAALQPQTLRKWGQ--LLLPSLLDLHLPRFSISGTYNLEDILPQIGLT 333 L D ++++ + P+ L +W + ++LHLPRF + Y+LE +L +G+ Sbjct: 247 LLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVLAAMGMG 306 Query: 334 NILN-LEADFSGVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDP-- 390 + + +AD+SG++ K H + V ++E+GTEA AA+G+ S P Sbjct: 307 DAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGI-----GFTVTSAPGH 361 Query: 391 -HAHFNRPFLLLLWEVTTQSLLFLGKVVNP 419 + H N PFL + + S+LF G+ +P Sbjct: 362 ENVHCNHPFLFFIRHNESNSILFFGRFSSP 391 >gi|154759291 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 [Homo sapiens] Length = 444 Score = 162 bits (410), Expect = 5e-40 Identities = 107/369 (28%), Positives = 192/369 (52%), Gaps = 11/369 (2%) Query: 55 TNFALRLYKELAADAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFN-LTETPEA 113 +NF L ++++ GN+ FSP +S + L LGA T I GL L T Sbjct: 80 SNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPG 139 Query: 114 DIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDS 173 + F+ L TL+ + +L L G+ F+ K ++ + + K + NF ++ Sbjct: 140 LLPSLFKGLRETLSR-NLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNA 198 Query: 174 VTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFF 233 R +N Y+ ++T G++ E + +T ++L +YI FK KW PF T+ ++F Sbjct: 199 SQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE-VDTFH 257 Query: 234 VDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDP-GKMKQVEAALQ 292 +D+ +++VPMM+ +D++ C VL++ Y+GNA L+VL + G +E L Sbjct: 258 LDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLT 317 Query: 293 PQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS--GVTGQLN 350 + W + + +++ P+F + Y + ++L Q+G+ I + AD S TG+ N Sbjct: 318 TDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGR-N 376 Query: 351 KTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSL 410 +S+V + ++++ E+GTE A +G+LS+ + + P +RPF +++E T+ L Sbjct: 377 LQVSRVLQRTVIEVDERGTE--AVAGILSEITAYS--MPPVIKVDRPFHFMIYEETSGML 432 Query: 411 LFLGKVVNP 419 LFLG+VVNP Sbjct: 433 LFLGRVVNP 441 >gi|7705879 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 [Homo sapiens] Length = 444 Score = 162 bits (410), Expect = 5e-40 Identities = 107/369 (28%), Positives = 192/369 (52%), Gaps = 11/369 (2%) Query: 55 TNFALRLYKELAADAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFN-LTETPEA 113 +NF L ++++ GN+ FSP +S + L LGA T I GL L T Sbjct: 80 SNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPG 139 Query: 114 DIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDS 173 + F+ L TL+ + +L L G+ F+ K ++ + + K + NF ++ Sbjct: 140 LLPSLFKGLRETLSR-NLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNA 198 Query: 174 VTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFF 233 R +N Y+ ++T G++ E + +T ++L +YI FK KW PF T+ ++F Sbjct: 199 SQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE-VDTFH 257 Query: 234 VDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDP-GKMKQVEAALQ 292 +D+ +++VPMM+ +D++ C VL++ Y+GNA L+VL + G +E L Sbjct: 258 LDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLT 317 Query: 293 PQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS--GVTGQLN 350 + W + + +++ P+F + Y + ++L Q+G+ I + AD S TG+ N Sbjct: 318 TDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGR-N 376 Query: 351 KTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSL 410 +S+V + ++++ E+GTE A +G+LS+ + + P +RPF +++E T+ L Sbjct: 377 LQVSRVLQRTVIEVDERGTE--AVAGILSEITAYS--MPPVIKVDRPFHFMIYEETSGML 432 Query: 411 LFLGKVVNP 419 LFLG+VVNP Sbjct: 433 LFLGRVVNP 441 >gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo sapiens] Length = 464 Score = 160 bits (405), Expect = 2e-39 Identities = 122/379 (32%), Positives = 204/379 (53%), Gaps = 19/379 (5%) Query: 55 TNFALRLYKELA--ADAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFN-LTETP 111 + FA Y+ LA + NIF SP+SIST A+ LGA +T ++E F+ ++E Sbjct: 88 SRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKT 147 Query: 112 EADIHQGFRSL---LHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSA 168 IH F L L+ A S KL N LF DK L + Y D + +YGA Sbjct: 148 SDQIHFFFAKLNCRLYRKANKSSKLVS--ANRLFGDKSLTFNETYQDISELVYGAKLQPL 205 Query: 169 NFTDSVTTGRQ-INDYLRRQTYGQVVDCLPE--FSQDTFMVLANYIFFKAKWKHPFSRYQ 225 +F ++ R IN ++ +T G++ D +P ++ T +VL N I+FK WK FS Sbjct: 206 DFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFSPEN 265 Query: 226 TQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALAL-LVLPDPGK- 283 T+K E F+ + S MM+Q+ R+ + VL++ ++G+ + + L+LP P K Sbjct: 266 TRK-ELFYKADGESCSASMMYQEGKFRYRRVAE-GTQVLELPFKGDDITMVLILPKPEKS 323 Query: 284 MKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLE-ADF 342 + +VE L P+ L++W L +L +H+PRF I ++L++ L +GL ++ + E + Sbjct: 324 LAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKL 383 Query: 343 SGVT--GQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLL 400 G+ G+ + +S HKA ++++E+G+EA A++ ++ SLN + NRPFL+ Sbjct: 384 PGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNP-NRVTFKANRPFLV 442 Query: 401 LLWEVTTQSLLFLGKVVNP 419 + EV +++F+G+V NP Sbjct: 443 FIREVPLNTIIFMGRVANP 461 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.136 0.406 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,465,377 Number of Sequences: 37866 Number of extensions: 743174 Number of successful extensions: 2223 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 62 Number of HSP's successfully gapped in prelim test: 3 Number of HSP's that attempted gapping in prelim test: 1936 Number of HSP's gapped (non-prelim): 69 length of query: 422 length of database: 18,247,518 effective HSP length: 105 effective length of query: 317 effective length of database: 14,271,588 effective search space: 4524093396 effective search space used: 4524093396 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.