Guide to the Human Genome
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Search of human proteins with 28827793

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28827793 dihydrofolate reductase-like 1 [Homo sapiens]
         (187 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28827793 dihydrofolate reductase-like 1 [Homo sapiens]             380   e-106
gi|4503323 dihydrofolate reductase [Homo sapiens]                     345   1e-95
gi|239748594 PREDICTED: hypothetical protein XP_002346735 [Homo ...   345   1e-95
gi|239787106 zinc finger protein 610 isoform b [Homo sapiens]          30   1.2  
gi|149192855 HLA-B associated transcript 2-like [Homo sapiens]         28   4.6  
gi|145046269 rotatin [Homo sapiens]                                    27   7.9  

>gi|28827793 dihydrofolate reductase-like 1 [Homo sapiens]
          Length = 187

 Score =  380 bits (977), Expect = e-106
 Identities = 187/187 (100%), Positives = 187/187 (100%)

Query: 1   MFLLLNCIVAVSQNMGIGKNGDLPRPPLRNEFRYFQRMTTTSSVEGKQNLVIMGRKTWFS 60
           MFLLLNCIVAVSQNMGIGKNGDLPRPPLRNEFRYFQRMTTTSSVEGKQNLVIMGRKTWFS
Sbjct: 1   MFLLLNCIVAVSQNMGIGKNGDLPRPPLRNEFRYFQRMTTTSSVEGKQNLVIMGRKTWFS 60

Query: 61  IPEKNRPLKDRINLVLSRELKEPPQGAHFLARSLDDALKLTERPELANKVDMIWIVGGSS 120
           IPEKNRPLKDRINLVLSRELKEPPQGAHFLARSLDDALKLTERPELANKVDMIWIVGGSS
Sbjct: 61  IPEKNRPLKDRINLVLSRELKEPPQGAHFLARSLDDALKLTERPELANKVDMIWIVGGSS 120

Query: 121 VYKEAMNHLGHLKLFVTRIMQDFESDTFFSEIDLEKYKLLPEYPGVLSDVQEGKHIKYKF 180
           VYKEAMNHLGHLKLFVTRIMQDFESDTFFSEIDLEKYKLLPEYPGVLSDVQEGKHIKYKF
Sbjct: 121 VYKEAMNHLGHLKLFVTRIMQDFESDTFFSEIDLEKYKLLPEYPGVLSDVQEGKHIKYKF 180

Query: 181 EVCEKDD 187
           EVCEKDD
Sbjct: 181 EVCEKDD 187


>gi|4503323 dihydrofolate reductase [Homo sapiens]
          Length = 187

 Score =  345 bits (886), Expect = 1e-95
 Identities = 171/183 (93%), Positives = 176/183 (96%)

Query: 5   LNCIVAVSQNMGIGKNGDLPRPPLRNEFRYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64
           LNCIVAVSQNMGIGKNGDLP PPLRNEFRYFQRMTTTSSVEGKQNLVIMG+KTWFSIPEK
Sbjct: 5   LNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEK 64

Query: 65  NRPLKDRINLVLSRELKEPPQGAHFLARSLDDALKLTERPELANKVDMIWIVGGSSVYKE 124
           NRPLK RINLVLSRELKEPPQGAHFL+RSLDDALKLTE+PELANKVDM+WIVGGSSVYKE
Sbjct: 65  NRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKE 124

Query: 125 AMNHLGHLKLFVTRIMQDFESDTFFSEIDLEKYKLLPEYPGVLSDVQEGKHIKYKFEVCE 184
           AMNH GHLKLFVTRIMQDFESDTFF EIDLEKYKLLPEYPGVLSDVQE K IKYKFEV E
Sbjct: 125 AMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYE 184

Query: 185 KDD 187
           K+D
Sbjct: 185 KND 187


>gi|239748594 PREDICTED: hypothetical protein XP_002346735 [Homo
           sapiens]
          Length = 262

 Score =  345 bits (886), Expect = 1e-95
 Identities = 171/183 (93%), Positives = 176/183 (96%)

Query: 5   LNCIVAVSQNMGIGKNGDLPRPPLRNEFRYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEK 64
           LNCIVAVSQNMGIGKNGDLP PPLRNEFRYFQRMTTTSSVEGKQNLVIMG+KTWFSIPEK
Sbjct: 80  LNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEK 139

Query: 65  NRPLKDRINLVLSRELKEPPQGAHFLARSLDDALKLTERPELANKVDMIWIVGGSSVYKE 124
           NRPLK RINLVLSRELKEPPQGAHFL+RSLDDALKLTE+PELANKVDM+WIVGGSSVYKE
Sbjct: 140 NRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKE 199

Query: 125 AMNHLGHLKLFVTRIMQDFESDTFFSEIDLEKYKLLPEYPGVLSDVQEGKHIKYKFEVCE 184
           AMNH GHLKLFVTRIMQDFESDTFF EIDLEKYKLLPEYPGVLSDVQE K IKYKFEV E
Sbjct: 200 AMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYE 259

Query: 185 KDD 187
           K+D
Sbjct: 260 KND 262


>gi|239787106 zinc finger protein 610 isoform b [Homo sapiens]
          Length = 419

 Score = 30.0 bits (66), Expect = 1.2
 Identities = 13/39 (33%), Positives = 22/39 (56%)

Query: 44 VEGKQNLVIMGRKTWFSIPEKNRPLKDRINLVLSRELKE 82
          +E  +NLV +GR        +N+P+K+++ L L   L E
Sbjct: 54 LENYRNLVFLGRSCVLGSNAENKPIKNQLGLTLEAHLSE 92


>gi|149192855 HLA-B associated transcript 2-like [Homo sapiens]
          Length = 2229

 Score = 28.1 bits (61), Expect = 4.6
 Identities = 16/49 (32%), Positives = 23/49 (46%)

Query: 7   CIVAVSQNMGIGKNGDLPRPPLRNEFRYFQRMTTTSSVEGKQNLVIMGR 55
           C    S+N G  + G  P P LR E R   R    +  +GK+N + + R
Sbjct: 287 CSPKSSENQGTVERGSFPLPQLRLEPRVPFRQFQMNDQDGKENRLGLSR 335


>gi|145046269 rotatin [Homo sapiens]
          Length = 2226

 Score = 27.3 bits (59), Expect = 7.9
 Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 5/59 (8%)

Query: 58  WFSIPEKNRPLKDRINLVLSRELKEPPQGAHFL---ARSLDDALKLTERPELANKVDMI 113
           WF+ P    P+K+ +  +LSR +K PP   H +   A      L+    P L  ++D I
Sbjct: 52  WFNFPSV--PMKEEVLNLLSRLVKYPPAVQHLVDVGAVEFLSKLRSNVEPNLQAEIDGI 108


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.138    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,383,364
Number of Sequences: 37866
Number of extensions: 297997
Number of successful extensions: 564
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 559
Number of HSP's gapped (non-prelim): 6
length of query: 187
length of database: 18,247,518
effective HSP length: 96
effective length of query: 91
effective length of database: 14,612,382
effective search space: 1329726762
effective search space used: 1329726762
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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