Search of human proteins with 27501450

Search of human proteins with 27501450

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27501450 axin 1 isoform a [Homo sapiens]
         (862 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27501450 axin 1 isoform a [Homo sapiens]                          1769   0.0  
gi|31083144 axin 1 isoform b [Homo sapiens]                          1680   0.0  
gi|195927059 axin 2 [Homo sapiens]                                    607   e-173
gi|19913392 regulator of G-protein signalling 3 isoform 4 [Homo ...    79   1e-14
gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo...    79   1e-14
gi|62865656 regulator of G-protein signalling 3 isoform 5 [Homo ...    79   1e-14
gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo ...    79   1e-14
gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo ...    79   1e-14
gi|4506505 regulator of G-protein signaling 10 isoform b [Homo s...    79   2e-14
gi|52694755 regulator of G-protein signaling 10 isoform a [Homo ...    79   2e-14
gi|4506519 regulator of G-protein signalling 5 [Homo sapiens]          75   3e-13
gi|18640750 regulator of G-protein signalling 18 [Homo sapiens]        74   4e-13
gi|115387108 regulator of G-protein signalling 1 [Homo sapiens]        74   6e-13
gi|85540441 regulator of G-protein signaling 21 [Homo sapiens]         74   8e-13
gi|16117777 regulator of G-protein signalling 8 isoform 1 [Homo ...    72   2e-12
gi|156416024 regulator of G-protein signalling 8 isoform 2 [Homo...    72   2e-12
gi|164664488 regulator of G-protein signaling 4 isoform 3 [Homo ...    69   2e-11
gi|5032039 regulator of G-protein signaling 4 isoform 2 [Homo sa...    69   2e-11
gi|156416012 regulator of G-protein signaling 4 isoform 1 [Homo ...    69   2e-11
gi|4506517 regulator of G-protein signaling 2, 24kDa [Homo sapiens]    68   3e-11
gi|21361405 regulator of G-protein signalling 17 [Homo sapiens]        63   1e-09
gi|21361304 regulator of G-protein signalling 14 [Homo sapiens]        63   1e-09
gi|13654235 regulator of G-protein signaling 20 isoform b [Homo ...    63   1e-09
gi|41281805 regulator of G-protein signaling 20 isoform a [Homo ...    63   1e-09
gi|156416009 regulator of G-protein signalling 16 [Homo sapiens]       63   1e-09
gi|86990435 G protein signalling regulator 19 [Homo sapiens]           62   2e-09
gi|5031705 G protein signalling regulator 19 [Homo sapiens]            62   2e-09
gi|4506511 regulator of G-protein signalling 13 [Homo sapiens]         60   9e-09
gi|21464139 regulator of G-protein signalling 13 [Homo sapiens]        60   9e-09
gi|4506509 regulator of G-protein signalling 12 isoform 2 [Homo ...    50   9e-06

>gi|27501450 axin 1 isoform a [Homo sapiens]
          Length = 862

 Score = 1769 bits (4583), Expect = 0.0
 Identities = 862/862 (100%), Positives = 862/862 (100%)

Query: 1   MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTAT 60
           MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTAT
Sbjct: 1   MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTAT 60

Query: 61  PRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA 120
           PRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA
Sbjct: 61  PRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA 120

Query: 121 CTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA 180
           CTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA
Sbjct: 121 CTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA 180

Query: 181 MFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPT 240
           MFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPT
Sbjct: 181 MFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPT 240

Query: 241 LNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREP 300
           LNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREP
Sbjct: 241 LNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREP 300

Query: 301 VNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESV 360
           VNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESV
Sbjct: 301 VNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESV 360

Query: 361 QVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEE 420
           QVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEE
Sbjct: 361 QVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEE 420

Query: 421 EGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLR 480
           EGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLR
Sbjct: 421 EGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLR 480

Query: 481 TPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVH 540
           TPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVH
Sbjct: 481 TPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVH 540

Query: 541 HSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGV 600
           HSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGV
Sbjct: 541 HSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGV 600

Query: 601 ACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQ 660
           ACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQ
Sbjct: 601 ACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQ 660

Query: 661 PHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKR 720
           PHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKR
Sbjct: 661 PHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKR 720

Query: 721 ASRAPSKQRYVQEVMRRGRACVRPACAPVLHVVPAVSDMELSETETRSQRKVGGGSAQPC 780
           ASRAPSKQRYVQEVMRRGRACVRPACAPVLHVVPAVSDMELSETETRSQRKVGGGSAQPC
Sbjct: 721 ASRAPSKQRYVQEVMRRGRACVRPACAPVLHVVPAVSDMELSETETRSQRKVGGGSAQPC 780

Query: 781 DSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEV 840
           DSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEV
Sbjct: 781 DSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEV 840

Query: 841 REDEAVLPVFEEKIIGKVEKVD 862
           REDEAVLPVFEEKIIGKVEKVD
Sbjct: 841 REDEAVLPVFEEKIIGKVEKVD 862


>gi|31083144 axin 1 isoform b [Homo sapiens]
          Length = 826

 Score = 1680 bits (4350), Expect = 0.0
 Identities = 826/862 (95%), Positives = 826/862 (95%), Gaps = 36/862 (4%)

Query: 1   MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTAT 60
           MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTAT
Sbjct: 1   MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTAT 60

Query: 61  PRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA 120
           PRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA
Sbjct: 61  PRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA 120

Query: 121 CTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA 180
           CTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA
Sbjct: 121 CTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA 180

Query: 181 MFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPT 240
           MFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPT
Sbjct: 181 MFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPT 240

Query: 241 LNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREP 300
           LNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREP
Sbjct: 241 LNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREP 300

Query: 301 VNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESV 360
           VNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESV
Sbjct: 301 VNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESV 360

Query: 361 QVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEE 420
           QVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEE
Sbjct: 361 QVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEE 420

Query: 421 EGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLR 480
           EGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLR
Sbjct: 421 EGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLR 480

Query: 481 TPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVH 540
           TPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVH
Sbjct: 481 TPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVH 540

Query: 541 HSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGV 600
           HSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGV
Sbjct: 541 HSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGV 600

Query: 601 ACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQ 660
           ACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQ
Sbjct: 601 ACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQ 660

Query: 661 PHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKR 720
           PHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKR
Sbjct: 661 PHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKR 720

Query: 721 ASRAPSKQRYVQEVMRRGRACVRPACAPVLHVVPAVSDMELSETETRSQRKVGGGSAQPC 780
           ASRAPSKQR                                    TRSQRKVGGGSAQPC
Sbjct: 721 ASRAPSKQR------------------------------------TRSQRKVGGGSAQPC 744

Query: 781 DSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEV 840
           DSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEV
Sbjct: 745 DSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEV 804

Query: 841 REDEAVLPVFEEKIIGKVEKVD 862
           REDEAVLPVFEEKIIGKVEKVD
Sbjct: 805 REDEAVLPVFEEKIIGKVEKVD 826


>gi|195927059 axin 2 [Homo sapiens]
          Length = 843

 Score =  607 bits (1566), Expect = e-173
 Identities = 380/895 (42%), Positives = 513/895 (57%), Gaps = 106/895 (11%)

Query: 11  DLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTATPRRSDLDLGY 70
           D  +SF EDAPRPPVPGEEGE     P         GKG   K    ++  RR++  LG 
Sbjct: 12  DPSSSFREDAPRPPVPGEEGETPPCQPGV-------GKGQVTKPMPVSSNTRRNEDGLG- 63

Query: 71  EPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPC 130
           EPEG ASP  P  +W +SLHSLL DQDG  LFRTFL++E C D LDFWFAC GFR++   
Sbjct: 64  EPEGRASPDSPLTRWTKSLHSLLGDQDGAYLFRTFLEREKCVDTLDFWFACNGFRQMNLK 123

Query: 131 DSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQ 190
           D+   K L++A+AIY++YI +NN IVS+Q KPATK++I+  I KQ ID  MFDQAQTEIQ
Sbjct: 124 DT---KTLRVAKAIYKRYI-ENNSIVSKQLKPATKTYIRDGIKKQQIDSIMFDQAQTEIQ 179

Query: 191 ATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPTLNEDEEWKCD 250
           + MEEN Y  FL SDIYLEY R+G E+    S+   G G+ K + GYLPTLNE+EEW C 
Sbjct: 180 SVMEENAYQMFLTSDIYLEYVRSGGENTAYMSN--GGLGSLKVVCGYLPTLNEEEEWTCA 237

Query: 251 QDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWR--EPVNPYYVNA 308
               +            P  + L +   R ++S R +E  +  Y S++  +PVNPY++ +
Sbjct: 238 DFKCKLS----------PTVVGLSSKTLRATASVRSTETVDSGYRSFKRSDPVNPYHIGS 287

Query: 309 GYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRI--RKQHRREMQESVQVNGRV 366
           GY  APATSANDSE  S +   D++S+TDSSVDGIPPYR+  +KQ +REM  SV+ NG+V
Sbjct: 288 GYVFAPATSANDSEISSDALTDDSMSMTDSSVDGIPPYRVGSKKQLQREMHRSVKANGQV 347

Query: 367 PLPHIPRTYRVPKEVR-VEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDG 425
            LPH PRT+R+PKE+  VEP  FA ELI RLE ++   E+   LEERL+++R +EE E  
Sbjct: 348 SLPHFPRTHRLPKEMTPVEPATFAAELISRLEKLKLELESRHSLEERLQQIREDEEREGS 407

Query: 426 DPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLRTPGRQ 485
           + +       +    AP  H  P   +  G      ++EE+P++ILD+H+ RVL+TPG Q
Sbjct: 408 ELT------LNSREGAPTQH--PLSLLPSG------SYEEDPQTILDDHLSRVLKTPGCQ 453

Query: 486 SPGPGH-----RSPDSGHV------------AKMPVALGGAASGHGKHVPKSGAKLDAAG 528
           SPG G      RSPD  H              K+P A     +      P  G K     
Sbjct: 454 SPGVGRYSPRSRSPDHHHHHHSQYHSLLPPGGKLPPAAASPGA-----CPLLGGK-GFVT 507

Query: 529 LHHHRHVHHHV--HHSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAP 586
               +HVHHH   HH+  + KE++EAEAT+R       G E + + ++ + +S++    P
Sbjct: 508 KQTTKHVHHHYIHHHAVPKTKEEIEAEATQRVHCFCPGGSEYYCY-SKCKSHSKAPETMP 566

Query: 587 NASDGLAHSGKVGVACKRNAKKAESGKSASTEVPGAS----------EDAEKNQKIMQWI 636
           +   G +    +    KRN K  E G +      GA           E+ +++Q + QW+
Sbjct: 567 SEQFGGSRGSTLP---KRNGKGTEPGLALPAREGGAPGGAGALQLPREEGDRSQDVWQWM 623

Query: 637 IEGEKEISRHRRTGHGSSGTRKPQPHENSRP-----LSLEHPWAGPQLRTSVQP-SHLFI 690
           +E E++    +   H +  T+K  P E++R       S  H W G        P +HLF 
Sbjct: 624 LESERQ---SKPKPHSAQSTKKAYPLESARSSPGERASRHHLWGGNSGHPRTTPRAHLFT 680

Query: 691 QDPTMPPHPAPNPLTQLEEARRRLEEEEKRASRAPSKQRYVQEVMRRGR---ACVRPACA 747
           QDP MPP   PN L QLEEA RRL E  K     P KQR      +R R   A V+    
Sbjct: 681 QDPAMPPLTPPNTLAQLEEACRRLAEVSK-----PPKQRCCVASQQRDRNHSATVQTGAT 735

Query: 748 PVLHVVPAVSDMELSETETRSQRKVGGGSAQPCDSIVVAYYFCGEPIPYRTLVRGRAVTL 807
           P        S+  L+  + +  +K+ G  A     +VV Y+FCGE IPYR +++ +++TL
Sbjct: 736 PF-------SNPSLAPEDHKEPKKLAGVHALQASELVVTYFFCGEEIPYRRMLKAQSLTL 788

Query: 808 GQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD 862
           G FKE L+KKG+YRYYFKK SDEF CG VFEE+ EDE VLP++E +I+GKVE++D
Sbjct: 789 GHFKEQLSKKGNYRYYFKKASDEFACGAVFEEIWEDETVLPMYEGRILGKVERID 843


>gi|19913392 regulator of G-protein signalling 3 isoform 4 [Homo
           sapiens]
          Length = 168

 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 55/172 (31%), Positives = 83/172 (48%), Gaps = 29/172 (16%)

Query: 62  RRSDLDLGYEPEGSAS-------PTPPY-LKWAESLHSLLDDQDGISLFRTFLKQEGCAD 113
           RR +   G  P G A        PT    LKW ESL  LL  + G+++F+ FL+ E   +
Sbjct: 9   RRRNESPGAPPAGKADKMMKSFKPTSEEALKWGESLEKLLVHKYGLAVFQAFLRTEFSEE 68

Query: 114 LLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYI-------LDNNGIVSRQTKPATKS 166
            L+FW AC  F+K++    ++ K    A+ I+ +YI       ++ +      TK   +S
Sbjct: 69  NLEFWLACEDFKKVK----SQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQS 124

Query: 167 FIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESP 218
             +GC          FD AQ  I   ME+++YP FL+SD+YL+       SP
Sbjct: 125 VTRGC----------FDLAQKRIFGLMEKDSYPRFLRSDLYLDLINQKKMSP 166


>gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo
            sapiens]
          Length = 1198

 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 55/172 (31%), Positives = 83/172 (48%), Gaps = 29/172 (16%)

Query: 62   RRSDLDLGYEPEGSAS-------PTPPY-LKWAESLHSLLDDQDGISLFRTFLKQEGCAD 113
            RR +   G  P G A        PT    LKW ESL  LL  + G+++F+ FL+ E   +
Sbjct: 1039 RRRNESPGAPPAGKADKMMKSFKPTSEEALKWGESLEKLLVHKYGLAVFQAFLRTEFSEE 1098

Query: 114  LLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYI-------LDNNGIVSRQTKPATKS 166
             L+FW AC  F+K++    ++ K    A+ I+ +YI       ++ +      TK   +S
Sbjct: 1099 NLEFWLACEDFKKVK----SQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQS 1154

Query: 167  FIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESP 218
              +GC          FD AQ  I   ME+++YP FL+SD+YL+       SP
Sbjct: 1155 VTRGC----------FDLAQKRIFGLMEKDSYPRFLRSDLYLDLINQKKMSP 1196


>gi|62865656 regulator of G-protein signalling 3 isoform 5 [Homo
           sapiens]
          Length = 311

 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 55/172 (31%), Positives = 83/172 (48%), Gaps = 29/172 (16%)

Query: 62  RRSDLDLGYEPEGSAS-------PTPPY-LKWAESLHSLLDDQDGISLFRTFLKQEGCAD 113
           RR +   G  P G A        PT    LKW ESL  LL  + G+++F+ FL+ E   +
Sbjct: 152 RRRNESPGAPPAGKADKMMKSFKPTSEEALKWGESLEKLLVHKYGLAVFQAFLRTEFSEE 211

Query: 114 LLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYI-------LDNNGIVSRQTKPATKS 166
            L+FW AC  F+K++    ++ K    A+ I+ +YI       ++ +      TK   +S
Sbjct: 212 NLEFWLACEDFKKVK----SQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQS 267

Query: 167 FIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESP 218
             +GC          FD AQ  I   ME+++YP FL+SD+YL+       SP
Sbjct: 268 VTRGC----------FDLAQKRIFGLMEKDSYPRFLRSDLYLDLINQKKMSP 309


>gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo
           sapiens]
          Length = 519

 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 55/172 (31%), Positives = 83/172 (48%), Gaps = 29/172 (16%)

Query: 62  RRSDLDLGYEPEGSAS-------PTPPY-LKWAESLHSLLDDQDGISLFRTFLKQEGCAD 113
           RR +   G  P G A        PT    LKW ESL  LL  + G+++F+ FL+ E   +
Sbjct: 360 RRRNESPGAPPAGKADKMMKSFKPTSEEALKWGESLEKLLVHKYGLAVFQAFLRTEFSEE 419

Query: 114 LLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYI-------LDNNGIVSRQTKPATKS 166
            L+FW AC  F+K++    ++ K    A+ I+ +YI       ++ +      TK   +S
Sbjct: 420 NLEFWLACEDFKKVK----SQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQS 475

Query: 167 FIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESP 218
             +GC          FD AQ  I   ME+++YP FL+SD+YL+       SP
Sbjct: 476 VTRGC----------FDLAQKRIFGLMEKDSYPRFLRSDLYLDLINQKKMSP 517


>gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo
           sapiens]
          Length = 917

 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 55/172 (31%), Positives = 83/172 (48%), Gaps = 29/172 (16%)

Query: 62  RRSDLDLGYEPEGSAS-------PTPPY-LKWAESLHSLLDDQDGISLFRTFLKQEGCAD 113
           RR +   G  P G A        PT    LKW ESL  LL  + G+++F+ FL+ E   +
Sbjct: 758 RRRNESPGAPPAGKADKMMKSFKPTSEEALKWGESLEKLLVHKYGLAVFQAFLRTEFSEE 817

Query: 114 LLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYI-------LDNNGIVSRQTKPATKS 166
            L+FW AC  F+K++    ++ K    A+ I+ +YI       ++ +      TK   +S
Sbjct: 818 NLEFWLACEDFKKVK----SQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQS 873

Query: 167 FIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESP 218
             +GC          FD AQ  I   ME+++YP FL+SD+YL+       SP
Sbjct: 874 VTRGC----------FDLAQKRIFGLMEKDSYPRFLRSDLYLDLINQKKMSP 915


>gi|4506505 regulator of G-protein signaling 10 isoform b [Homo
           sapiens]
          Length = 167

 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 51/161 (31%), Positives = 88/161 (54%), Gaps = 12/161 (7%)

Query: 70  YEPEGSASPTPPYLK----WAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFR 125
           ++ +GS+S +   LK    WA SL +LL+D +G+  FR FLK+E   + + FW AC  F+
Sbjct: 5   HDSDGSSSSSHQSLKSTAKWAASLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEDFK 64

Query: 126 KLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQA 185
           K++     +EK    A+ IY  ++   +   S Q     +S +   I+++   P MF + 
Sbjct: 65  KMQDKTQMQEK----AKEIYMTFL---SSKASSQVNVEGQSRLNEKILEE-PHPLMFQKL 116

Query: 186 QTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSS 226
           Q +I   M+ ++Y  FLKSD++L++ RT  E   +   Q++
Sbjct: 117 QDQIFNLMKYDSYSRFLKSDLFLKHKRTEEEEEDLPDAQTA 157


>gi|52694755 regulator of G-protein signaling 10 isoform a [Homo
           sapiens]
          Length = 181

 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 51/161 (31%), Positives = 88/161 (54%), Gaps = 12/161 (7%)

Query: 70  YEPEGSASPTPPYLK----WAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFR 125
           ++ +GS+S +   LK    WA SL +LL+D +G+  FR FLK+E   + + FW AC  F+
Sbjct: 19  HDSDGSSSSSHQSLKSTAKWAASLENLLEDPEGVKRFREFLKKEFSEENVLFWLACEDFK 78

Query: 126 KLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQA 185
           K++     +EK    A+ IY  ++   +   S Q     +S +   I+++   P MF + 
Sbjct: 79  KMQDKTQMQEK----AKEIYMTFL---SSKASSQVNVEGQSRLNEKILEE-PHPLMFQKL 130

Query: 186 QTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSS 226
           Q +I   M+ ++Y  FLKSD++L++ RT  E   +   Q++
Sbjct: 131 QDQIFNLMKYDSYSRFLKSDLFLKHKRTEEEEEDLPDAQTA 171


>gi|4506519 regulator of G-protein signalling 5 [Homo sapiens]
          Length = 181

 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 42/129 (32%), Positives = 71/129 (55%), Gaps = 11/129 (8%)

Query: 83  LKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLAR 142
           L+W +SL  LL +  G++ F++FLK E   + L+FW AC  ++K++    +  K  + A+
Sbjct: 59  LQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIK----SPAKMAEKAK 114

Query: 143 AIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAM--FDQAQTEIQATMEENTYPS 200
            IY ++I           +     F K   MK L++P++  FD AQ  I A ME+++ P 
Sbjct: 115 QIYEEFIQ-----TEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPR 169

Query: 201 FLKSDIYLE 209
           F++S+ Y E
Sbjct: 170 FVRSEFYQE 178


>gi|18640750 regulator of G-protein signalling 18 [Homo sapiens]
          Length = 235

 Score = 74.3 bits (181), Expect = 4e-13
 Identities = 48/139 (34%), Positives = 70/139 (50%), Gaps = 13/139 (9%)

Query: 83  LKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLAR 142
           +KW ES   LL  +DG+  F  FLK E   + ++FW AC  F+K +     ++  LK A+
Sbjct: 81  VKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSK---GPQQIHLK-AK 136

Query: 143 AIYRKYILDNNGIVSRQTKPATKSF-IKGCIMKQLIDPAM--FDQAQTEIQATMEENTYP 199
           AIY K+I  +        K     F  K  I   +  P +  FD AQ+ +   ME+++Y 
Sbjct: 137 AIYEKFIQTD------APKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYT 190

Query: 200 SFLKSDIYLEYTRTGSESP 218
            FLKSDIYL+      + P
Sbjct: 191 RFLKSDIYLDLMEGRPQRP 209


>gi|115387108 regulator of G-protein signalling 1 [Homo sapiens]
          Length = 209

 Score = 73.9 bits (180), Expect = 6e-13
 Identities = 45/133 (33%), Positives = 71/133 (53%), Gaps = 22/133 (16%)

Query: 83  LKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLE----PCDSNEEKRL 138
           ++W++SL  LL +Q G ++F +FLK E   + ++FW AC  ++K E    PC + E    
Sbjct: 80  MQWSQSLEKLLANQTGQNVFGSFLKSEFSEENIEFWLACEDYKKTESDLLPCKAEE---- 135

Query: 139 KLARAIYRKYILDNNG---IVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEE 195
                IY+ ++  +      +  +T+ +T   IK         P  FD+AQ  I   ME+
Sbjct: 136 -----IYKAFVHSDAAKQINIDFRTRESTAKKIKA------PTPTCFDEAQKVIYTLMEK 184

Query: 196 NTYPSFLKSDIYL 208
           ++YP FLKSDIYL
Sbjct: 185 DSYPRFLKSDIYL 197


>gi|85540441 regulator of G-protein signaling 21 [Homo sapiens]
          Length = 152

 Score = 73.6 bits (179), Expect = 8e-13
 Identities = 45/134 (33%), Positives = 72/134 (53%), Gaps = 13/134 (9%)

Query: 77  SPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEK 136
           SPT   + W+E++ +LL +Q G+  FR FLK E   + ++FW AC  F+K +    N +K
Sbjct: 10  SPTAETMTWSENMDTLLANQAGLDAFRIFLKSEFSEENVEFWLACEDFKKTK----NADK 65

Query: 137 RLKLARAIYRKYILDNNGIVSRQTKPATKSF-IKGCIMKQLIDPAM--FDQAQTEIQATM 193
               A+ IY ++      I +   K     F  +  I K + +P +  FD+AQ  I   M
Sbjct: 66  IASKAKMIYSEF------IEADAPKEINIDFGTRDLISKNIAEPTLKCFDEAQKLIYCLM 119

Query: 194 EENTYPSFLKSDIY 207
            ++++P FLKS+IY
Sbjct: 120 AKDSFPRFLKSEIY 133


>gi|16117777 regulator of G-protein signalling 8 isoform 1 [Homo
           sapiens]
          Length = 198

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 43/131 (32%), Positives = 72/131 (54%), Gaps = 17/131 (12%)

Query: 84  KWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARA 143
           +WA+S   LL  + G++ FR FLK E   + L+FW AC  F+K      +  K +  A  
Sbjct: 70  RWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTR----STAKLVSKAHR 125

Query: 144 IYRKYI---LDNNGIVSRQTKPATKSFIKGCIMKQLIDPAM--FDQAQTEIQATMEENTY 198
           I+ +++         +  QT+ AT+        K L +P++  FDQAQ ++ + ME+++Y
Sbjct: 126 IFEEFVDVQAPREVNIDFQTREATR--------KNLQEPSLTCFDQAQGKVHSLMEKDSY 177

Query: 199 PSFLKSDIYLE 209
           P FL+S +YL+
Sbjct: 178 PRFLRSKMYLD 188


>gi|156416024 regulator of G-protein signalling 8 isoform 2 [Homo
           sapiens]
          Length = 180

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 43/131 (32%), Positives = 72/131 (54%), Gaps = 17/131 (12%)

Query: 84  KWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARA 143
           +WA+S   LL  + G++ FR FLK E   + L+FW AC  F+K      +  K +  A  
Sbjct: 52  RWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTR----STAKLVSKAHR 107

Query: 144 IYRKYI---LDNNGIVSRQTKPATKSFIKGCIMKQLIDPAM--FDQAQTEIQATMEENTY 198
           I+ +++         +  QT+ AT+        K L +P++  FDQAQ ++ + ME+++Y
Sbjct: 108 IFEEFVDVQAPREVNIDFQTREATR--------KNLQEPSLTCFDQAQGKVHSLMEKDSY 159

Query: 199 PSFLKSDIYLE 209
           P FL+S +YL+
Sbjct: 160 PRFLRSKMYLD 170


>gi|164664488 regulator of G-protein signaling 4 isoform 3 [Homo
           sapiens]
          Length = 187

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 41/134 (30%), Positives = 71/134 (52%), Gaps = 11/134 (8%)

Query: 84  KWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARA 143
           KWAESL +L+  + G++ F+ FLK E   + +DFW +C  ++K++    +  K    A+ 
Sbjct: 40  KWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIK----SPSKLSPKAKK 95

Query: 144 IYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAM--FDQAQTEIQATMEENTYPSF 201
           IY ++I      V    +    S  +    + +++P +  FD+AQ +I   ME+++Y  F
Sbjct: 96  IYNEFI-----SVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRF 150

Query: 202 LKSDIYLEYTRTGS 215
           LKS  YL+     S
Sbjct: 151 LKSRFYLDLVNPSS 164


>gi|5032039 regulator of G-protein signaling 4 isoform 2 [Homo
           sapiens]
          Length = 205

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 41/134 (30%), Positives = 71/134 (52%), Gaps = 11/134 (8%)

Query: 84  KWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARA 143
           KWAESL +L+  + G++ F+ FLK E   + +DFW +C  ++K++    +  K    A+ 
Sbjct: 58  KWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIK----SPSKLSPKAKK 113

Query: 144 IYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAM--FDQAQTEIQATMEENTYPSF 201
           IY ++I      V    +    S  +    + +++P +  FD+AQ +I   ME+++Y  F
Sbjct: 114 IYNEFI-----SVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRF 168

Query: 202 LKSDIYLEYTRTGS 215
           LKS  YL+     S
Sbjct: 169 LKSRFYLDLVNPSS 182


>gi|156416012 regulator of G-protein signaling 4 isoform 1 [Homo
           sapiens]
          Length = 302

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 41/134 (30%), Positives = 71/134 (52%), Gaps = 11/134 (8%)

Query: 84  KWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARA 143
           KWAESL +L+  + G++ F+ FLK E   + +DFW +C  ++K++    +  K    A+ 
Sbjct: 155 KWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIK----SPSKLSPKAKK 210

Query: 144 IYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAM--FDQAQTEIQATMEENTYPSF 201
           IY ++I      V    +    S  +    + +++P +  FD+AQ +I   ME+++Y  F
Sbjct: 211 IYNEFI-----SVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRF 265

Query: 202 LKSDIYLEYTRTGS 215
           LKS  YL+     S
Sbjct: 266 LKSRFYLDLVNPSS 279


>gi|4506517 regulator of G-protein signaling 2, 24kDa [Homo sapiens]
          Length = 211

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 45/155 (29%), Positives = 73/155 (47%), Gaps = 14/155 (9%)

Query: 57  STATPRRSDLDLGYEPEGSASPTPPYLK-WAESLHSLLDDQDGISLFRTFLKQEGCADLL 115
           +++TP +       + +    P+P   + W+E+   LL  + G++ FR FLK E C + +
Sbjct: 51  NSSTPGKPKTGKKSKQQAFIKPSPEEAQLWSEAFDELLASKYGLAAFRAFLKSEFCEENI 110

Query: 116 DFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQ 175
           +FW AC  F+K +    + +K    AR IY  +      I     K     F    ++ Q
Sbjct: 111 EFWLACEDFKKTK----SPQKLSSKARKIYTDF------IEKEAPKEINIDFQTKTLIAQ 160

Query: 176 LIDPA---MFDQAQTEIQATMEENTYPSFLKSDIY 207
            I  A    F  AQ  + + ME N+YP FL+S+ Y
Sbjct: 161 NIQEATSGCFTTAQKRVYSLMENNSYPRFLESEFY 195


>gi|21361405 regulator of G-protein signalling 17 [Homo sapiens]
          Length = 210

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 43/137 (31%), Positives = 70/137 (51%), Gaps = 11/137 (8%)

Query: 83  LKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLAR 142
           L W+++   ++    G +LFR FL+ E   + L FW AC   +K +     EEK    AR
Sbjct: 79  LSWSQNFDKMMKAPAGRNLFREFLRTEYSEENLLFWLACEDLKKEQNKKVIEEK----AR 134

Query: 143 AIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLID--PAMFDQAQTEIQATMEENTYPS 200
            IY  YI     I+S + + +  S ++  I + L+D  P M++ AQ +I   M  +++P 
Sbjct: 135 MIYEDYI----SILSPK-EVSLDSRVREVINRNLLDPNPHMYEDAQLQIYTLMHRDSFPR 189

Query: 201 FLKSDIYLEYTRTGSES 217
           FL S IY  +  + + S
Sbjct: 190 FLNSQIYKSFVESTAGS 206


>gi|21361304 regulator of G-protein signalling 14 [Homo sapiens]
          Length = 566

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 58/213 (27%), Positives = 95/213 (44%), Gaps = 26/213 (12%)

Query: 25  VPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTATPRRSDLDLGYEPEGSASPTP---- 80
           VP     L  +D   +S +   G+G G          R S L +   P G +SP P    
Sbjct: 10  VPNGRMVLAVSDGELSSTTGPQGQGEG----------RGSSLSIHSLPSGPSSPFPTEEQ 59

Query: 81  PYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKL 140
           P   WA S   LL D  G++ F  FLK+E  A+ + FW AC  F+++   D+  ++  + 
Sbjct: 60  PVASWALSFERLLQDPLGLAYFTEFLKKEFSAENVTFWKACERFQQIPASDT--QQLAQE 117

Query: 141 ARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLI---DPAMFDQAQTEIQATMEENT 197
           AR IY++++       S Q         +  + ++++    P MF   Q +I   M+ ++
Sbjct: 118 ARNIYQEFL-------SSQALSPVNIDRQAWLGEEVLAEPRPDMFRAQQLQIFNLMKFDS 170

Query: 198 YPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGT 230
           Y  F+KS +Y E     +E   +    SS  G+
Sbjct: 171 YARFVKSPLYRECLLAEAEGRPLREPGSSRLGS 203


>gi|13654235 regulator of G-protein signaling 20 isoform b [Homo
           sapiens]
          Length = 241

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 46/150 (30%), Positives = 75/150 (50%), Gaps = 14/150 (9%)

Query: 72  PEGSASPTPPYLK---WAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLE 128
           P    SP P   +   WA+S   L+    G + FR FL+ E   + + FW AC   +K  
Sbjct: 96  PTWEESPAPTLEEVNAWAQSFDKLMVTPAGRNAFREFLRTEFSEENMLFWMACEELKKEA 155

Query: 129 PCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA--MFDQAQ 186
             +  EEK    AR IY  YI     I+S + + +  S ++  I + +++P+  +FD AQ
Sbjct: 156 NKNIIEEK----ARIIYEDYI----SILSPK-EVSLDSRVREVINRNMVEPSQHIFDDAQ 206

Query: 187 TEIQATMEENTYPSFLKSDIYLEYTRTGSE 216
            +I   M  ++YP F+ S +Y +  ++ SE
Sbjct: 207 LQIYTLMHRDSYPRFMNSAVYKDLLQSLSE 236


>gi|41281805 regulator of G-protein signaling 20 isoform a [Homo
           sapiens]
          Length = 388

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 46/150 (30%), Positives = 75/150 (50%), Gaps = 14/150 (9%)

Query: 72  PEGSASPTPPYLK---WAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLE 128
           P    SP P   +   WA+S   L+    G + FR FL+ E   + + FW AC   +K  
Sbjct: 243 PTWEESPAPTLEEVNAWAQSFDKLMVTPAGRNAFREFLRTEFSEENMLFWMACEELKKEA 302

Query: 129 PCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA--MFDQAQ 186
             +  EEK    AR IY  YI     I+S + + +  S ++  I + +++P+  +FD AQ
Sbjct: 303 NKNIIEEK----ARIIYEDYI----SILSPK-EVSLDSRVREVINRNMVEPSQHIFDDAQ 353

Query: 187 TEIQATMEENTYPSFLKSDIYLEYTRTGSE 216
            +I   M  ++YP F+ S +Y +  ++ SE
Sbjct: 354 LQIYTLMHRDSYPRFMNSAVYKDLLQSLSE 383


>gi|156416009 regulator of G-protein signalling 16 [Homo sapiens]
          Length = 202

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 42/146 (28%), Positives = 65/146 (44%), Gaps = 13/146 (8%)

Query: 83  LKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLAR 142
           L W ES   LL  ++G++ F  FLK E   + L+FW AC  F+K+     +  K    A 
Sbjct: 60  LGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIR----SATKLASRAH 115

Query: 143 AIYRKYILD---NNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYP 199
            I+ ++I         +  +T   T+  +      Q      FD AQ + +  ME+++YP
Sbjct: 116 QIFEEFICSEAPKEVNIDHETHELTRMNL------QTATATCFDAAQGKTRTLMEKDSYP 169

Query: 200 SFLKSDIYLEYTRTGSESPKVCSDQS 225
            FLKS  Y +     S +    S  S
Sbjct: 170 RFLKSPAYRDLAAQASAASATLSSCS 195


>gi|86990435 G protein signalling regulator 19 [Homo sapiens]
          Length = 217

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 56/197 (28%), Positives = 87/197 (44%), Gaps = 16/197 (8%)

Query: 18  EDAPRPPVPGEEGELVSTDP--RPASYSFCSGKGVGIKGETSTA--TPRRSDLDLGYEPE 73
           E+A RPP            P   P    +C         E   A    R S L      E
Sbjct: 15  EEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQASRESKLQPLPSCE 74

Query: 74  GSASPTPPYLK-WAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDS 132
             A+P+P  ++ WA+S   L+    G S+FR FL+ E   + + FW AC   +     ++
Sbjct: 75  VCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELK----AEA 130

Query: 133 NEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA--MFDQAQTEIQ 190
           N+    + AR IY  Y+     I+S + + +  S ++  I K++ +P+   FD AQ +I 
Sbjct: 131 NQHVVDEKARLIYEDYV----SILSPK-EVSLDSRVREGINKKMQEPSAHTFDDAQLQIY 185

Query: 191 ATMEENTYPSFLKSDIY 207
             M  ++YP FL S  Y
Sbjct: 186 TLMHRDSYPRFLSSPTY 202


>gi|5031705 G protein signalling regulator 19 [Homo sapiens]
          Length = 217

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 56/197 (28%), Positives = 87/197 (44%), Gaps = 16/197 (8%)

Query: 18  EDAPRPPVPGEEGELVSTDP--RPASYSFCSGKGVGIKGETSTA--TPRRSDLDLGYEPE 73
           E+A RPP            P   P    +C         E   A    R S L      E
Sbjct: 15  EEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQASRESKLQPLPSCE 74

Query: 74  GSASPTPPYLK-WAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDS 132
             A+P+P  ++ WA+S   L+    G S+FR FL+ E   + + FW AC   +     ++
Sbjct: 75  VCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELK----AEA 130

Query: 133 NEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA--MFDQAQTEIQ 190
           N+    + AR IY  Y+     I+S + + +  S ++  I K++ +P+   FD AQ +I 
Sbjct: 131 NQHVVDEKARLIYEDYV----SILSPK-EVSLDSRVREGINKKMQEPSAHTFDDAQLQIY 185

Query: 191 ATMEENTYPSFLKSDIY 207
             M  ++YP FL S  Y
Sbjct: 186 TLMHRDSYPRFLSSPTY 202


>gi|4506511 regulator of G-protein signalling 13 [Homo sapiens]
          Length = 159

 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 35/133 (26%), Positives = 70/133 (52%), Gaps = 11/133 (8%)

Query: 83  LKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLAR 142
           L+WA+S  +L+  + G  ++  +LK E   + + FW AC  ++K+    ++   R+  A+
Sbjct: 29  LQWAQSFENLMATKYGPVVYAAYLKMEHSDENIQFWMACETYKKI----ASRWSRISRAK 84

Query: 143 AIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDP--AMFDQAQTEIQATMEENTYPS 200
            +Y+ YI   +       +    S  +  I++ + +P    F++AQ  +   ME ++YP 
Sbjct: 85  KLYKIYIQPQS-----PREINIDSSTRETIIRNIQEPTETCFEEAQKIVYMHMERDSYPR 139

Query: 201 FLKSDIYLEYTRT 213
           FLKS++Y +  +T
Sbjct: 140 FLKSEMYQKLLKT 152


>gi|21464139 regulator of G-protein signalling 13 [Homo sapiens]
          Length = 159

 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 35/133 (26%), Positives = 70/133 (52%), Gaps = 11/133 (8%)

Query: 83  LKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLAR 142
           L+WA+S  +L+  + G  ++  +LK E   + + FW AC  ++K+    ++   R+  A+
Sbjct: 29  LQWAQSFENLMATKYGPVVYAAYLKMEHSDENIQFWMACETYKKI----ASRWSRISRAK 84

Query: 143 AIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDP--AMFDQAQTEIQATMEENTYPS 200
            +Y+ YI   +       +    S  +  I++ + +P    F++AQ  +   ME ++YP 
Sbjct: 85  KLYKIYIQPQS-----PREINIDSSTRETIIRNIQEPTETCFEEAQKIVYMHMERDSYPR 139

Query: 201 FLKSDIYLEYTRT 213
           FLKS++Y +  +T
Sbjct: 140 FLKSEMYQKLLKT 152


>gi|4506509 regulator of G-protein signalling 12 isoform 2 [Homo
           sapiens]
          Length = 1376

 Score = 50.1 bits (118), Expect = 9e-06
 Identities = 41/132 (31%), Positives = 57/132 (43%), Gaps = 20/132 (15%)

Query: 85  WAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAI 144
           WA S   LL D  G+  F  FL++E   + + FW AC  F  +   D  E      AR I
Sbjct: 712 WAVSFERLLQDPVGVRYFSDFLRKEFSEENILFWQACEYFNHVPAHDKKELS--YRAREI 769

Query: 145 YRKYILDNNGIVSRQTKPATKSFIKGCIMKQLID-------PAMFDQAQTEIQATMEENT 197
           + K+      + S+ T P            QL D       P MF + Q +I   M+ ++
Sbjct: 770 FSKF------LCSKATTPVNID-----SQAQLADDVLRAPHPDMFKEQQLQIFNLMKFDS 818

Query: 198 YPSFLKSDIYLE 209
           Y  FLKS +Y E
Sbjct: 819 YTRFLKSPLYQE 830


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,845,682
Number of Sequences: 37866
Number of extensions: 2209188
Number of successful extensions: 10950
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 120
Number of HSP's successfully gapped in prelim test: 201
Number of HSP's that attempted gapping in prelim test: 9693
Number of HSP's gapped (non-prelim): 953
length of query: 862
length of database: 18,247,518
effective HSP length: 111
effective length of query: 751
effective length of database: 14,044,392
effective search space: 10547338392
effective search space used: 10547338392
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.