Search of human proteins with 118442845

Search of human proteins with 118442845

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|118442845 N-acylsphingosine amidohydrolase (non-lysosomal
ceramidase) 2B [Homo sapiens]
         (165 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|118442845 N-acylsphingosine amidohydrolase (non-lysosomal cer...   340   3e-94
gi|221307475 N-acylsphingosine amidohydrolase 2 isoform b [Homo ...   286   7e-78
gi|221218981 N-acylsphingosine amidohydrolase 2 isoform a [Homo ...   286   7e-78
gi|89031073 PREDICTED: N-acylsphingosine amidohydrolase (non-lys...   284   3e-77
gi|4505245 mannose receptor C type 1 precursor [Homo sapiens]          31   0.43 
gi|57546917 mannose receptor, C type 1-like 1 [Homo sapiens]           31   0.43 
gi|25777602 proteasome 26S non-ATPase subunit 2 [Homo sapiens]         30   1.2  
gi|31881675 synaptotagmin XV isoform a [Homo sapiens]                  29   2.1  
gi|31881667 synaptotagmin XV isoform b [Homo sapiens]                  29   2.1  
gi|226442729 kelch-like 15 [Homo sapiens]                              27   8.0  
gi|171460956 ubiquitin specific peptidase like 1 [Homo sapiens]        27   8.0  

>gi|118442845 N-acylsphingosine amidohydrolase (non-lysosomal
           ceramidase) 2B [Homo sapiens]
          Length = 165

 Score =  340 bits (873), Expect = 3e-94
 Identities = 165/165 (100%), Positives = 165/165 (100%)

Query: 1   MRQHRQFMDRTHYLLTFSSSETLLRLLLRIVDRAPKGRTFGDVLQPAKPEYRVGEVAEVI 60
           MRQHRQFMDRTHYLLTFSSSETLLRLLLRIVDRAPKGRTFGDVLQPAKPEYRVGEVAEVI
Sbjct: 1   MRQHRQFMDRTHYLLTFSSSETLLRLLLRIVDRAPKGRTFGDVLQPAKPEYRVGEVAEVI 60

Query: 61  FVGANPKNSVQNQTHQTFLTVEKYEATSTSWQIVCNDASWETRFYWHKGLLGLSNATVEW 120
           FVGANPKNSVQNQTHQTFLTVEKYEATSTSWQIVCNDASWETRFYWHKGLLGLSNATVEW
Sbjct: 61  FVGANPKNSVQNQTHQTFLTVEKYEATSTSWQIVCNDASWETRFYWHKGLLGLSNATVEW 120

Query: 121 HIPDTAQPGIYRIRYFGHNRKQDILKPAVILSFEGTSPAFEVVTI 165
           HIPDTAQPGIYRIRYFGHNRKQDILKPAVILSFEGTSPAFEVVTI
Sbjct: 121 HIPDTAQPGIYRIRYFGHNRKQDILKPAVILSFEGTSPAFEVVTI 165


>gi|221307475 N-acylsphingosine amidohydrolase 2 isoform b [Homo
           sapiens]
          Length = 745

 Score =  286 bits (731), Expect = 7e-78
 Identities = 137/145 (94%), Positives = 141/145 (97%)

Query: 21  ETLLRLLLRIVDRAPKGRTFGDVLQPAKPEYRVGEVAEVIFVGANPKNSVQNQTHQTFLT 80
           + ++ L+  IVDRAPKGRTFGDVLQPAKPEYRVGEVAEVIFVGANPKNSVQNQTHQTFLT
Sbjct: 601 QLIVPLIPSIVDRAPKGRTFGDVLQPAKPEYRVGEVAEVIFVGANPKNSVQNQTHQTFLT 660

Query: 81  VEKYEATSTSWQIVCNDASWETRFYWHKGLLGLSNATVEWHIPDTAQPGIYRIRYFGHNR 140
           VEKYEATSTSWQIVCNDASWETRFYWHKGLLGLSNATVEWHIPDTAQPGIYRIRYFGHNR
Sbjct: 661 VEKYEATSTSWQIVCNDASWETRFYWHKGLLGLSNATVEWHIPDTAQPGIYRIRYFGHNR 720

Query: 141 KQDILKPAVILSFEGTSPAFEVVTI 165
           KQDILKPAVILSFEGTSPAFEVVTI
Sbjct: 721 KQDILKPAVILSFEGTSPAFEVVTI 745


>gi|221218981 N-acylsphingosine amidohydrolase 2 isoform a [Homo
           sapiens]
          Length = 780

 Score =  286 bits (731), Expect = 7e-78
 Identities = 137/145 (94%), Positives = 141/145 (97%)

Query: 21  ETLLRLLLRIVDRAPKGRTFGDVLQPAKPEYRVGEVAEVIFVGANPKNSVQNQTHQTFLT 80
           + ++ L+  IVDRAPKGRTFGDVLQPAKPEYRVGEVAEVIFVGANPKNSVQNQTHQTFLT
Sbjct: 636 QLIVPLIPSIVDRAPKGRTFGDVLQPAKPEYRVGEVAEVIFVGANPKNSVQNQTHQTFLT 695

Query: 81  VEKYEATSTSWQIVCNDASWETRFYWHKGLLGLSNATVEWHIPDTAQPGIYRIRYFGHNR 140
           VEKYEATSTSWQIVCNDASWETRFYWHKGLLGLSNATVEWHIPDTAQPGIYRIRYFGHNR
Sbjct: 696 VEKYEATSTSWQIVCNDASWETRFYWHKGLLGLSNATVEWHIPDTAQPGIYRIRYFGHNR 755

Query: 141 KQDILKPAVILSFEGTSPAFEVVTI 165
           KQDILKPAVILSFEGTSPAFEVVTI
Sbjct: 756 KQDILKPAVILSFEGTSPAFEVVTI 780


>gi|89031073 PREDICTED: N-acylsphingosine amidohydrolase
           (non-lysosomal ceramidase) 2C [Homo sapiens]
          Length = 622

 Score =  284 bits (726), Expect = 3e-77
 Identities = 136/145 (93%), Positives = 140/145 (96%)

Query: 21  ETLLRLLLRIVDRAPKGRTFGDVLQPAKPEYRVGEVAEVIFVGANPKNSVQNQTHQTFLT 80
           + ++ L+  IVDRAPKGRTFGDVLQPAKPEYRVGEVAEVIFVGANPKNSVQNQ HQTFLT
Sbjct: 478 QLIVPLIPSIVDRAPKGRTFGDVLQPAKPEYRVGEVAEVIFVGANPKNSVQNQNHQTFLT 537

Query: 81  VEKYEATSTSWQIVCNDASWETRFYWHKGLLGLSNATVEWHIPDTAQPGIYRIRYFGHNR 140
           VEKYEATSTSWQIVCNDASWETRFYWHKGLLGLSNATVEWHIPDTAQPGIYRIRYFGHNR
Sbjct: 538 VEKYEATSTSWQIVCNDASWETRFYWHKGLLGLSNATVEWHIPDTAQPGIYRIRYFGHNR 597

Query: 141 KQDILKPAVILSFEGTSPAFEVVTI 165
           KQDILKPAVILSFEGTSPAFEVVTI
Sbjct: 598 KQDILKPAVILSFEGTSPAFEVVTI 622


>gi|4505245 mannose receptor C type 1 precursor [Homo sapiens]
          Length = 1456

 Score = 31.2 bits (69), Expect = 0.43
 Identities = 15/41 (36%), Positives = 23/41 (56%), Gaps = 1/41 (2%)

Query: 69   SVQNQTHQTFLTVEKYEATSTSWQIVCNDASWETRFYWHKG 109
            S+QN+  Q FLT    ++T ++W  + ND + E  F W  G
Sbjct: 986  SIQNEKEQAFLTYHMKDSTFSAWTGL-NDVNSEHTFLWTDG 1025


>gi|57546917 mannose receptor, C type 1-like 1 [Homo sapiens]
          Length = 1456

 Score = 31.2 bits (69), Expect = 0.43
 Identities = 15/41 (36%), Positives = 23/41 (56%), Gaps = 1/41 (2%)

Query: 69   SVQNQTHQTFLTVEKYEATSTSWQIVCNDASWETRFYWHKG 109
            S+QN+  Q FLT    ++T ++W  + ND + E  F W  G
Sbjct: 986  SIQNEKEQAFLTYHMKDSTFSAWTGL-NDVNSEHTFLWTDG 1025


>gi|25777602 proteasome 26S non-ATPase subunit 2 [Homo sapiens]
          Length = 908

 Score = 29.6 bits (65), Expect = 1.2
 Identities = 14/39 (35%), Positives = 19/39 (48%)

Query: 39  TFGDVLQPAKPEYRVGEVAEVIFVGANPKNSVQNQTHQT 77
           TF + L+P     RVG+  +V+     PK     QTH T
Sbjct: 832 TFDEELRPLPVSVRVGQAVDVVGQAGKPKTITGFQTHTT 870


>gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
          Length = 421

 Score = 28.9 bits (63), Expect = 2.1
 Identities = 18/53 (33%), Positives = 28/53 (52%), Gaps = 3/53 (5%)

Query: 12  HYLLTFSS---SETLLRLLLRIVDRAPKGRTFGDVLQPAKPEYRVGEVAEVIF 61
           H++   SS   ++ +L+  +  VDR  K +  G VL P K E  VG+   VI+
Sbjct: 213 HFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVIW 265


>gi|31881667 synaptotagmin XV isoform b [Homo sapiens]
          Length = 390

 Score = 28.9 bits (63), Expect = 2.1
 Identities = 18/53 (33%), Positives = 28/53 (52%), Gaps = 3/53 (5%)

Query: 12  HYLLTFSS---SETLLRLLLRIVDRAPKGRTFGDVLQPAKPEYRVGEVAEVIF 61
           H++   SS   ++ +L+  +  VDR  K +  G VL P K E  VG+   VI+
Sbjct: 213 HFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVIW 265


>gi|226442729 kelch-like 15 [Homo sapiens]
          Length = 604

 Score = 26.9 bits (58), Expect = 8.0
 Identities = 15/62 (24%), Positives = 28/62 (45%), Gaps = 9/62 (14%)

Query: 48  KPEYRVGEVAEVIFVGANPKNSVQNQTHQTFLTVEKYEATSTSWQIVCNDASWETRFYWH 107
           + E+ VG + + I+  A           +TF + E+Y+ T+  W+ V     +    Y H
Sbjct: 369 RSEFAVGVIGKFIYAVAGRTRD------ETFYSTERYDITNDKWEFV---DPYPVNKYGH 419

Query: 108 KG 109
           +G
Sbjct: 420 EG 421


>gi|171460956 ubiquitin specific peptidase like 1 [Homo sapiens]
          Length = 1092

 Score = 26.9 bits (58), Expect = 8.0
 Identities = 14/49 (28%), Positives = 21/49 (42%)

Query: 81  VEKYEATSTSWQIVCNDASWETRFYWHKGLLGLSNATVEWHIPDTAQPG 129
           +EK    S SW   C+    + +    K L+  +N   EWH  + A  G
Sbjct: 347 IEKLFLYSFSWDFECSQCGHQYQNRHMKSLVTFTNVIPEWHPLNAAHFG 395


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,332,858
Number of Sequences: 37866
Number of extensions: 261779
Number of successful extensions: 488
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 480
Number of HSP's gapped (non-prelim): 11
length of query: 165
length of database: 18,247,518
effective HSP length: 94
effective length of query: 71
effective length of database: 14,688,114
effective search space: 1042856094
effective search space used: 1042856094
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.