Guide to the Human Genome
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Search of human proteins with 239748466

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239748466 PREDICTED: similar to zinc finger and BTB domain
containing 8 opposite strand [Homo sapiens]
         (202 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239748466 PREDICTED: similar to zinc finger and BTB domain co...   407   e-114
gi|169164528 PREDICTED: similar to zinc finger and BTB domain co...   222   1e-58
gi|113414298 PREDICTED: similar to zinc finger and BTB domain co...   222   1e-58
gi|113413492 PREDICTED: similar to zinc finger and BTB domain co...   222   1e-58
gi|30425510 zinc finger and BTB domain containing 8 opposite str...   198   2e-51
gi|4559408 colony stimulating factor 2 receptor, beta precursor ...    29   3.1  
gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo ...    29   3.1  
gi|11225260 DNA topoisomerase I [Homo sapiens]                         28   6.9  
gi|34452688 regulator of G-protein signalling 11 isoform 1 [Homo...    28   6.9  
gi|4506507 regulator of G-protein signalling 11 isoform 2 [Homo ...    28   6.9  
gi|40548387 O-acyltransferase (membrane bound) domain containing...    27   9.0  

>gi|239748466 PREDICTED: similar to zinc finger and BTB domain
           containing 8 opposite strand [Homo sapiens]
          Length = 202

 Score =  407 bits (1046), Expect = e-114
 Identities = 202/202 (100%), Positives = 202/202 (100%)

Query: 1   MKHVDPVAGSHKASMREARLEIVYTSGDRELKELQENGARSLPQSLYISVLLIRDIILLH 60
           MKHVDPVAGSHKASMREARLEIVYTSGDRELKELQENGARSLPQSLYISVLLIRDIILLH
Sbjct: 1   MKHVDPVAGSHKASMREARLEIVYTSGDRELKELQENGARSLPQSLYISVLLIRDIILLH 60

Query: 61  NLSSKAVMAQKEGDVRDYNLTEEQKAIKANYPPVNRNYEYLDHTADVQLHTWGDTLEEAF 120
           NLSSKAVMAQKEGDVRDYNLTEEQKAIKANYPPVNRNYEYLDHTADVQLHTWGDTLEEAF
Sbjct: 61  NLSSKAVMAQKEGDVRDYNLTEEQKAIKANYPPVNRNYEYLDHTADVQLHTWGDTLEEAF 120

Query: 121 EQCAMAIFGYMIDTRTVEPLQTIEVETQEVSTFLFHFLDEWLYKSNADEFFIPWEVKRRI 180
           EQCAMAIFGYMIDTRTVEPLQTIEVETQEVSTFLFHFLDEWLYKSNADEFFIPWEVKRRI
Sbjct: 121 EQCAMAIFGYMIDTRTVEPLQTIEVETQEVSTFLFHFLDEWLYKSNADEFFIPWEVKRRI 180

Query: 181 FIVQSPSGNRSQSYNIFSNAGL 202
           FIVQSPSGNRSQSYNIFSNAGL
Sbjct: 181 FIVQSPSGNRSQSYNIFSNAGL 202


>gi|169164528 PREDICTED: similar to zinc finger and BTB domain
           containing 8 opposite strand [Homo sapiens]
          Length = 136

 Score =  222 bits (566), Expect = 1e-58
 Identities = 111/137 (81%), Positives = 118/137 (86%), Gaps = 3/137 (2%)

Query: 68  MAQKEGDVRDYNLTEEQKAIKANYPPVNRNYEYLDHTADVQLHTWGDTLEEAFEQCAMAI 127
           MAQ E DVRDYNLTEEQKAIKA YPPVNR YEYLDHTADVQLH WGDTLEEAFEQCAMA+
Sbjct: 1   MAQAEEDVRDYNLTEEQKAIKAKYPPVNRKYEYLDHTADVQLHAWGDTLEEAFEQCAMAM 60

Query: 128 FGYMIDTRTVEPLQTIEVETQ--EVSTFLFHFLDEWLYKSNADEFFIPWEVKRRIFIVQS 185
           FGYM DT TVEPL T+EVETQ  ++ T LFHFLDEWLYK +ADEFFIP  V RR+FIVQ+
Sbjct: 61  FGYMTDTGTVEPLPTVEVETQGNDLQTLLFHFLDEWLYKFSADEFFIP-RVGRRVFIVQA 119

Query: 186 PSGNRSQSYNIFSNAGL 202
            SGNRSQ  NIFSNAGL
Sbjct: 120 SSGNRSQGNNIFSNAGL 136


>gi|113414298 PREDICTED: similar to zinc finger and BTB domain
           containing 8 opposite strand [Homo sapiens]
          Length = 136

 Score =  222 bits (566), Expect = 1e-58
 Identities = 111/137 (81%), Positives = 118/137 (86%), Gaps = 3/137 (2%)

Query: 68  MAQKEGDVRDYNLTEEQKAIKANYPPVNRNYEYLDHTADVQLHTWGDTLEEAFEQCAMAI 127
           MAQ E DVRDYNLTEEQKAIKA YPPVNR YEYLDHTADVQLH WGDTLEEAFEQCAMA+
Sbjct: 1   MAQAEEDVRDYNLTEEQKAIKAKYPPVNRKYEYLDHTADVQLHAWGDTLEEAFEQCAMAM 60

Query: 128 FGYMIDTRTVEPLQTIEVETQ--EVSTFLFHFLDEWLYKSNADEFFIPWEVKRRIFIVQS 185
           FGYM DT TVEPL T+EVETQ  ++ T LFHFLDEWLYK +ADEFFIP  V RR+FIVQ+
Sbjct: 61  FGYMTDTGTVEPLPTVEVETQGNDLQTLLFHFLDEWLYKFSADEFFIP-RVGRRVFIVQA 119

Query: 186 PSGNRSQSYNIFSNAGL 202
            SGNRSQ  NIFSNAGL
Sbjct: 120 SSGNRSQGNNIFSNAGL 136


>gi|113413492 PREDICTED: similar to zinc finger and BTB domain
           containing 8 opposite strand [Homo sapiens]
          Length = 136

 Score =  222 bits (566), Expect = 1e-58
 Identities = 111/137 (81%), Positives = 118/137 (86%), Gaps = 3/137 (2%)

Query: 68  MAQKEGDVRDYNLTEEQKAIKANYPPVNRNYEYLDHTADVQLHTWGDTLEEAFEQCAMAI 127
           MAQ E DVRDYNLTEEQKAIKA YPPVNR YEYLDHTADVQLH WGDTLEEAFEQCAMA+
Sbjct: 1   MAQAEEDVRDYNLTEEQKAIKAKYPPVNRKYEYLDHTADVQLHAWGDTLEEAFEQCAMAM 60

Query: 128 FGYMIDTRTVEPLQTIEVETQ--EVSTFLFHFLDEWLYKSNADEFFIPWEVKRRIFIVQS 185
           FGYM DT TVEPL T+EVETQ  ++ T LFHFLDEWLYK +ADEFFIP  V RR+FIVQ+
Sbjct: 61  FGYMTDTGTVEPLPTVEVETQGNDLQTLLFHFLDEWLYKFSADEFFIP-RVGRRVFIVQA 119

Query: 186 PSGNRSQSYNIFSNAGL 202
            SGNRSQ  NIFSNAGL
Sbjct: 120 SSGNRSQGNNIFSNAGL 136


>gi|30425510 zinc finger and BTB domain containing 8 opposite strand
           [Homo sapiens]
          Length = 179

 Score =  198 bits (504), Expect = 2e-51
 Identities = 96/118 (81%), Positives = 105/118 (88%), Gaps = 2/118 (1%)

Query: 62  LSSKAVMAQKEGDVRDYNLTEEQKAIKANYPPVNRNYEYLDHTADVQLHTWGDTLEEAFE 121
           +S+ AVMAQ+E DVRDYNLTEEQKAIKA YPPVNR YEYLDHTADVQLH WGDTLEEAFE
Sbjct: 7   VSNPAVMAQEEEDVRDYNLTEEQKAIKAKYPPVNRKYEYLDHTADVQLHAWGDTLEEAFE 66

Query: 122 QCAMAIFGYMIDTRTVEPLQTIEVETQ--EVSTFLFHFLDEWLYKSNADEFFIPWEVK 177
           QCAMA+FGYM DT TVEPLQT+EVETQ  ++ + LFHFLDEWLYK +ADEFFIP EVK
Sbjct: 67  QCAMAMFGYMTDTGTVEPLQTVEVETQGDDLQSLLFHFLDEWLYKFSADEFFIPREVK 124


>gi|4559408 colony stimulating factor 2 receptor, beta precursor
           [Homo sapiens]
          Length = 897

 Score = 28.9 bits (63), Expect = 3.1
 Identities = 12/47 (25%), Positives = 24/47 (51%), Gaps = 4/47 (8%)

Query: 79  NLTEEQKAIKANYPPVNRNYEYLDHTADVQLH----TWGDTLEEAFE 121
           N+T++  +    +  +   YE++DHT ++Q      TW D+  E  +
Sbjct: 346 NVTKDGDSYSLRWETMKMRYEHIDHTFEIQYRKDTATWKDSKTETLQ 392


>gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo
           sapiens]
          Length = 581

 Score = 28.9 bits (63), Expect = 3.1
 Identities = 37/167 (22%), Positives = 72/167 (43%), Gaps = 14/167 (8%)

Query: 14  SMREARLEIVYTSGDRELKELQENGARSLPQSLYISVLLIRDIILLHNLSSKAVMAQKEG 73
           S+R   + I     + EL +L  N  RSL ++++  ++ ++++ L HN  SK  +A    
Sbjct: 168 SLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPR 227

Query: 74  DVRDYNLTEEQKAIKANYPPVNRNYEYLDHTADVQLHTWGDTLEEAFEQCAMAIFGYMID 133
            V   NL  +   I      ++  +  L      +L   G+ + EAF     ++F     
Sbjct: 228 LVSLQNLYLQWNKISVIGQTMSWTWSSLQ-----RLDLSGNEI-EAFS--GPSVF----- 274

Query: 134 TRTVEPLQTIEVETQEVSTFLFHFLDEWLYKSNADEFFIPWEVKRRI 180
            + V  LQ + +++ +++      LD W+  ++       WE  R I
Sbjct: 275 -QCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAGNIWECSRNI 320


>gi|11225260 DNA topoisomerase I [Homo sapiens]
          Length = 765

 Score = 27.7 bits (60), Expect = 6.9
 Identities = 17/48 (35%), Positives = 25/48 (52%), Gaps = 5/48 (10%)

Query: 2   KHVDPVAGSHKASMREA-----RLEIVYTSGDRELKELQENGARSLPQ 44
           KH D  +  HK   ++      + E V  SGD ++K+ +ENG  S PQ
Sbjct: 68  KHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQ 115


>gi|34452688 regulator of G-protein signalling 11 isoform 1 [Homo
           sapiens]
          Length = 467

 Score = 27.7 bits (60), Expect = 6.9
 Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 19/99 (19%)

Query: 99  EYLDHTADVQLHTWGDTLEEAFEQCAMAIFGYMIDTRTVEPLQTIE---------VETQE 149
           E L + A  Q+ T  D + E F     A +   ID+RT+E  QT+E         ++  +
Sbjct: 337 EELRYGAQAQVPTLVDAVYEQFLAPGAAHW-VNIDSRTME--QTLEGLRQPHRYVLDDAQ 393

Query: 150 VSTFLF-------HFLDEWLYKSNADEFFIPWEVKRRIF 181
           +  ++         FL   +YK+   E  IP E+KRR+F
Sbjct: 394 LHIYMLMKKDSYPRFLKSDMYKALLAEAGIPLEMKRRVF 432


>gi|4506507 regulator of G-protein signalling 11 isoform 2 [Homo
           sapiens]
          Length = 446

 Score = 27.7 bits (60), Expect = 6.9
 Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 19/99 (19%)

Query: 99  EYLDHTADVQLHTWGDTLEEAFEQCAMAIFGYMIDTRTVEPLQTIE---------VETQE 149
           E L + A  Q+ T  D + E F     A +   ID+RT+E  QT+E         ++  +
Sbjct: 316 EELRYGAQAQVPTLVDAVYEQFLAPGAAHW-VNIDSRTME--QTLEGLRQPHRYVLDDAQ 372

Query: 150 VSTFLF-------HFLDEWLYKSNADEFFIPWEVKRRIF 181
           +  ++         FL   +YK+   E  IP E+KRR+F
Sbjct: 373 LHIYMLMKKDSYPRFLKSDMYKALLAEAGIPLEMKRRVF 411


>gi|40548387 O-acyltransferase (membrane bound) domain containing 2
           [Homo sapiens]
          Length = 520

 Score = 27.3 bits (59), Expect = 9.0
 Identities = 33/147 (22%), Positives = 58/147 (39%), Gaps = 10/147 (6%)

Query: 17  EARLEIVYTSGDRELKELQENGARSLPQSLYISVLLIRDIILLHNLSSKAVMAQKEGDVR 76
           E R   +  SG+   +E Q       P +  +  LL+  + LL +L+    +        
Sbjct: 203 EGRSYHITQSGENGKEETQYERTEPSPNTAVVQKLLVCGLSLLFHLTICTTLPV------ 256

Query: 77  DYNLTEEQKAIKANYPPVNRNYEYLDHTADVQLHTWGDTLEEAFEQCA-MAIFGYMID-T 134
           +YN+ E  +A  +   P    Y Y+   A    + +  TL +A    A     GY  +  
Sbjct: 257 EYNIDEHFQATAS--WPTKIIYLYISLLAARPKYYFAWTLADAINNAAGFGFRGYDENGA 314

Query: 135 RTVEPLQTIEVETQEVSTFLFHFLDEW 161
              + +  + ++  E+ST    FLD W
Sbjct: 315 ARWDLISNLRIQQIEMSTSFKMFLDNW 341


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,107,493
Number of Sequences: 37866
Number of extensions: 270680
Number of successful extensions: 653
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 640
Number of HSP's gapped (non-prelim): 11
length of query: 202
length of database: 18,247,518
effective HSP length: 97
effective length of query: 105
effective length of database: 14,574,516
effective search space: 1530324180
effective search space used: 1530324180
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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