Search of human proteins with 117306169

Search of human proteins with 117306169

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|117306169 prolylcarboxypeptidase isoform 2 preproprotein
[Homo sapiens]
         (517 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|117306169 prolylcarboxypeptidase isoform 2 preproprotein [Hom...  1078   0.0  
gi|4826940 prolylcarboxypeptidase isoform 1 preproprotein [Homo ...  1023   0.0  
gi|62420888 dipeptidyl peptidase 7 preproprotein [Homo sapiens]       354   9e-98
gi|5031993 protease, serine, 16 [Homo sapiens]                        129   6e-30
gi|15100151 HLA-B associated transcript 5 [Homo sapiens]               33   0.63 
gi|28629871 hypothetical protein LOC140701 [Homo sapiens]              32   1.4  
gi|7662058 tectonin beta-propeller repeat containing 2 [Homo sap...    30   6.9  
gi|222080058 Smith-Magenis syndrome chromosome region, candidate...    30   6.9  
gi|22538488 Smith-Magenis syndrome chromosome region, candidate ...    30   6.9  

>gi|117306169 prolylcarboxypeptidase isoform 2 preproprotein [Homo
           sapiens]
          Length = 517

 Score = 1078 bits (2789), Expect = 0.0
 Identities = 517/517 (100%), Positives = 517/517 (100%)

Query: 1   MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKALAA 60
           MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKALAA
Sbjct: 1   MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKALAA 60

Query: 61  GQLHICIIQLNHYKTPLVDHFGFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWF 120
           GQLHICIIQLNHYKTPLVDHFGFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWF
Sbjct: 61  GQLHICIIQLNHYKTPLVDHFGFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWF 120

Query: 121 CNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIK 180
           CNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIK
Sbjct: 121 CNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIK 180

Query: 181 HLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFM 240
           HLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFM
Sbjct: 181 HLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFM 240

Query: 241 KIVTTDFRKSGPHCSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWI 300
           KIVTTDFRKSGPHCSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWI
Sbjct: 241 KIVTTDFRKSGPHCSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWI 300

Query: 301 SETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSG 360
           SETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSG
Sbjct: 301 SETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSG 360

Query: 361 QVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWG 420
           QVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWG
Sbjct: 361 QVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWG 420

Query: 421 VRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDL 480
           VRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDL
Sbjct: 421 VRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDL 480

Query: 481 RTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGKQH 517
           RTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGKQH
Sbjct: 481 RTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGKQH 517


>gi|4826940 prolylcarboxypeptidase isoform 1 preproprotein [Homo
           sapiens]
          Length = 496

 Score = 1023 bits (2646), Expect = 0.0
 Identities = 496/517 (95%), Positives = 496/517 (95%), Gaps = 21/517 (4%)

Query: 1   MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKALAA 60
           MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQK    
Sbjct: 1   MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQK---- 56

Query: 61  GQLHICIIQLNHYKTPLVDHFGFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWF 120
                            VDHFGFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWF
Sbjct: 57  -----------------VDHFGFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWF 99

Query: 121 CNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIK 180
           CNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIK
Sbjct: 100 CNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIK 159

Query: 181 HLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFM 240
           HLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFM
Sbjct: 160 HLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFM 219

Query: 241 KIVTTDFRKSGPHCSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWI 300
           KIVTTDFRKSGPHCSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWI
Sbjct: 220 KIVTTDFRKSGPHCSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWI 279

Query: 301 SETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSG 360
           SETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSG
Sbjct: 280 SETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSG 339

Query: 361 QVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWG 420
           QVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWG
Sbjct: 340 QVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWG 399

Query: 421 VRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDL 480
           VRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDL
Sbjct: 400 VRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDL 459

Query: 481 RTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGKQH 517
           RTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGKQH
Sbjct: 460 RTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGKQH 496


>gi|62420888 dipeptidyl peptidase 7 preproprotein [Homo sapiens]
          Length = 492

 Score =  354 bits (909), Expect = 9e-98
 Identities = 192/444 (43%), Positives = 267/444 (60%), Gaps = 23/444 (5%)

Query: 78  VDHFGFNTV--KTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELK 135
           +DHF F     KTF QR+LV+D++W +  G I FYTGNEGD+  F NN+ F+ ++A E  
Sbjct: 40  LDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERG 99

Query: 136 AMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVI 195
           A+LVFAEHRYYG+SLPFG  S +   H   LT EQALADFAEL++ L+R + GA++ P I
Sbjct: 100 ALLVFAEHRYYGKSLPFGAQSTQRG-HTELLTVEQALADFAELLRALRRDL-GAQDAPAI 157

Query: 196 AIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCS 255
           A GGSYGGML+A+ RMKYPH+V GALAASAP+     L     F + VT DF    P C+
Sbjct: 158 AFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCT 217

Query: 256 ESIHRSWDAINRLSNTGS--GLQWLTGALHLCSPLTSQ-DIQHLKDWISETWVNLAMVDY 312
           + +  ++  I  L   G+   ++W  G    C PL+ + D+  L  +    +  LAM+DY
Sbjct: 218 QGVREAFRQIKDLFLQGAYDTVRWEFGT---CQPLSDEKDLTQLFMFARNAFTVLAMMDY 274

Query: 313 PYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETAT 372
           PY ++FL PLPA P+KV C  L    +S++  +  +     + YN SG   C +I     
Sbjct: 275 PYPTDFLGPLPANPVKVGCDRL----LSEAQRITGLRALAGLVYNASGSEHCYDIYRLYH 330

Query: 373 SSLGTLG---------WSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRP 423
           S     G         W YQACTE+ + F +N V DMF    +  +     C   WGV P
Sbjct: 331 SCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWP 390

Query: 424 RPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTK 483
           RP W+ T + G ++ + +NI+FSNG LDPW+GGG+ ++++ +++AVTI  GAHHLDLR  
Sbjct: 391 RPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRAS 450

Query: 484 NALDPMSVLLARSLEVRHMKNWIR 507
           +  DP SV+ AR LE   +  W++
Sbjct: 451 HPEDPASVVEARKLEATIIGEWVK 474


>gi|5031993 protease, serine, 16 [Homo sapiens]
          Length = 514

 Score =  129 bits (324), Expect = 6e-30
 Identities = 122/452 (26%), Positives = 195/452 (43%), Gaps = 34/452 (7%)

Query: 77  LVDHFGFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKA 136
           L+D F  +  ++F QRY V D++W    G I  + G EG +       G    +A    A
Sbjct: 65  LLDPFNVSDRRSFLQRYWVNDQHWVGQDGPIFLHLGGEGSLGPGSVMRGHPAALAPAWGA 124

Query: 137 MLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIA 196
           +++  EHR+YG S+P G     +   L FL+S  ALAD       L R    + + P I 
Sbjct: 125 LVISLEHRFYGLSIPAGG---LEMAQLRFLSSRLALADVVSARLALSRLFNISSSSPWIC 181

Query: 197 IGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCG-VFMKIVTTDFRKSGPHCS 255
            GGSY G LAAW R+K+PH++  ++A+SAP+    D      V  + + +        C 
Sbjct: 182 FGGSYAGSLAAWARLKFPHLIFASVASSAPVRAVLDFSEYNDVVSRSLMSTAIGGSLECR 241

Query: 256 ESIHRSWDAINRLSNTGSGLQ-WLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPY 314
            ++  ++  + R   +G   Q  L   L  C PL   + Q       +  V   +V Y  
Sbjct: 242 AAVSVAFAEVERRLRSGGAAQAALRTELSACGPLGRAENQAELLGALQALVG-GVVQYDG 300

Query: 315 ASNFLQPLPAWPIKVVCQYL--KNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETAT 372
            +    PL    ++ +C  L     N S S     + +A+ +  +  GQ KCL+ S   T
Sbjct: 301 QTG--APL---SVRQLCGLLLGGGGNRSHSTPYCGLRRAVQIVLHSLGQ-KCLSFSRAET 354

Query: 373 -----------SSLGTLGWSYQACTEV-VMPFCTNGVDDMFEPHSWNLKELSDDCFQQWG 420
                      S +G   W YQ CTE      C N      +  +  L    D C Q +G
Sbjct: 355 VAQLRSTEPQLSGVGDRQWLYQTCTEFGFYVTCENPRCPFSQLPA--LPSQLDLCEQVFG 412

Query: 421 -----VRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGA 475
                V    +   + YGG+   ++  ++F NG+ DPW    VT+ +  +   + I  G+
Sbjct: 413 LSALSVAQAVAQTNSYYGGQTPGAN-KVLFVNGDTDPWHVLSVTQALGSSESTLLIRTGS 471

Query: 476 HHLDLRTKNALDPMSVLLARSLEVRHMKNWIR 507
           H LD+  +   D  S+ L R    + ++ W++
Sbjct: 472 HCLDMAPERPSDSPSLRLGRQNIFQQLQTWLK 503


>gi|15100151 HLA-B associated transcript 5 [Homo sapiens]
          Length = 558

 Score = 33.1 bits (74), Expect = 0.63
 Identities = 21/61 (34%), Positives = 30/61 (49%), Gaps = 7/61 (11%)

Query: 188 GAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDF 247
           G + Q +I    S GG  A W  M YP +    L AS     F+DLVP  + +K++   +
Sbjct: 343 GFQPQDIIIYAWSIGGFTATWAAMSYPDVSAMILDAS-----FDDLVP--LALKVMPDSW 395

Query: 248 R 248
           R
Sbjct: 396 R 396


>gi|28629871 hypothetical protein LOC140701 [Homo sapiens]
          Length = 469

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 5/42 (11%)

Query: 194 VIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVP 235
           ++  G S GG  A W  M YP +  GAL   A    F+DLVP
Sbjct: 241 LVVYGWSVGGFTATWATMTYPEL--GALVLDA---TFDDLVP 277


>gi|7662058 tectonin beta-propeller repeat containing 2 [Homo sapiens]
          Length = 1411

 Score = 29.6 bits (65), Expect = 6.9
 Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 5/42 (11%)

Query: 91   QRYLVADK-----YWKKNGGSILFYTGNEGDIIWFCNNTGFM 127
            +RY V DK     YWKK  GS+  +T    D +W     G++
Sbjct: 1335 RRYGVTDKNPAGDYWKKIPGSVSCFTVTASDELWAVGPPGYL 1376


>gi|222080058 Smith-Magenis syndrome chromosome region, candidate 7
           isoform 2 [Homo sapiens]
          Length = 465

 Score = 29.6 bits (65), Expect = 6.9
 Identities = 14/44 (31%), Positives = 21/44 (47%)

Query: 185 TIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIW 228
           TIP A+      + G     L A+FR K+P +  GA     P++
Sbjct: 151 TIPAAQVALAKQLAGDIALELQAYFRSKFPELPFGAFVPGGPLY 194


>gi|22538488 Smith-Magenis syndrome chromosome region, candidate 7
           isoform 1 [Homo sapiens]
          Length = 454

 Score = 29.6 bits (65), Expect = 6.9
 Identities = 14/44 (31%), Positives = 21/44 (47%)

Query: 185 TIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIW 228
           TIP A+      + G     L A+FR K+P +  GA     P++
Sbjct: 140 TIPAAQVALAKQLAGDIALELQAYFRSKFPELPFGAFVPGGPLY 183


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.437 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,381,366
Number of Sequences: 37866
Number of extensions: 903806
Number of successful extensions: 1777
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1760
Number of HSP's gapped (non-prelim): 9
length of query: 517
length of database: 18,247,518
effective HSP length: 107
effective length of query: 410
effective length of database: 14,195,856
effective search space: 5820300960
effective search space used: 5820300960
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.