Guide to the Human Genome
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Search of human proteins with 117190262

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|117190262 diphthine synthase isoform a [Homo sapiens]
         (285 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|117190326 diphthine synthase isoform a [Homo sapiens]              564   e-161
gi|117190262 diphthine synthase isoform a [Homo sapiens]              564   e-161
gi|117190324 diphthine synthase isoform b [Homo sapiens]              558   e-159
gi|38504671 secernin 3 [Homo sapiens]                                  31   1.1  
gi|194097432 hypothetical protein LOC285966 B [Homo sapiens]           29   4.1  
gi|194097428 hypothetical protein LOC285966 A [Homo sapiens]           29   4.1  
gi|194097425 hypothetical protein LOC285966 A [Homo sapiens]           29   4.1  
gi|21362074 testes development-related NYD-SP22 isoform 1 [Homo ...    28   7.0  
gi|225543215 antigen identified by monoclonal antibody Ki-67 iso...    28   9.2  
gi|103472005 antigen identified by monoclonal antibody Ki-67 iso...    28   9.2  
gi|83776596 CaM kinase-like vesicle-associated [Homo sapiens]          28   9.2  
gi|62953116 BTB (POZ) domain containing 11 isoform b [Homo sapiens]    28   9.2  
gi|65786661 BTB (POZ) domain containing 11 isoform a [Homo sapiens]    28   9.2  

>gi|117190326 diphthine synthase isoform a [Homo sapiens]
          Length = 285

 Score =  564 bits (1454), Expect = e-161
 Identities = 285/285 (100%), Positives = 285/285 (100%)

Query: 1   MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE 60
           MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE
Sbjct: 1   MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE 60

Query: 61  VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC 120
           VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC
Sbjct: 61  VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC 120

Query: 121 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK 180
           GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK
Sbjct: 121 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK 180

Query: 181 IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQM 240
           IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQM
Sbjct: 181 IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQM 240

Query: 241 CTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL 285
           CTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL
Sbjct: 241 CTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL 285


>gi|117190262 diphthine synthase isoform a [Homo sapiens]
          Length = 285

 Score =  564 bits (1454), Expect = e-161
 Identities = 285/285 (100%), Positives = 285/285 (100%)

Query: 1   MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE 60
           MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE
Sbjct: 1   MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE 60

Query: 61  VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC 120
           VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC
Sbjct: 61  VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC 120

Query: 121 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK 180
           GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK
Sbjct: 121 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK 180

Query: 181 IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQM 240
           IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQM
Sbjct: 181 IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQM 240

Query: 241 CTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL 285
           CTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL
Sbjct: 241 CTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL 285


>gi|117190324 diphthine synthase isoform b [Homo sapiens]
          Length = 284

 Score =  558 bits (1438), Expect = e-159
 Identities = 284/285 (99%), Positives = 284/285 (99%), Gaps = 1/285 (0%)

Query: 1   MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE 60
           MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE
Sbjct: 1   MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE 60

Query: 61  VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC 120
           VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC
Sbjct: 61  VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC 120

Query: 121 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK 180
           GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK
Sbjct: 121 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK 180

Query: 181 IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQM 240
           IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEP VTEETLCVGLARVGADDQKIAAGTLRQM
Sbjct: 181 IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEP-VTEETLCVGLARVGADDQKIAAGTLRQM 239

Query: 241 CTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL 285
           CTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL
Sbjct: 240 CTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL 284


>gi|38504671 secernin 3 [Homo sapiens]
          Length = 424

 Score = 31.2 bits (69), Expect = 1.1
 Identities = 17/46 (36%), Positives = 24/46 (52%)

Query: 158 HTLCLLDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIVQN 203
           H   LLD       LE+L+K +  ++P R   + Q  QQ LE+V N
Sbjct: 317 HISQLLDTSSPTFELEDLVKKKSHFKPDRRHPLYQKHQQALEVVNN 362


>gi|194097432 hypothetical protein LOC285966 B [Homo sapiens]
          Length = 564

 Score = 29.3 bits (64), Expect = 4.1
 Identities = 19/83 (22%), Positives = 36/83 (43%), Gaps = 6/83 (7%)

Query: 185 PRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEE------TLCVGLARVGADDQKIAAGTLR 238
           P Y+S+++  +++L       +  E P  ++       +L  GLA  G D  ++A G   
Sbjct: 175 PAYISLHRLLRKMLRGSGLPAVSRENPVASDSYEAAVLSLATGLAHSGTDCSQLAQGLGT 234

Query: 239 QMCTVDLGEPLHSLIITGGSIHP 261
             C+  L    H + +    I+P
Sbjct: 235 WTCSSSLYPSKHPITVEINGINP 257


>gi|194097428 hypothetical protein LOC285966 A [Homo sapiens]
          Length = 845

 Score = 29.3 bits (64), Expect = 4.1
 Identities = 19/83 (22%), Positives = 36/83 (43%), Gaps = 6/83 (7%)

Query: 185 PRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEE------TLCVGLARVGADDQKIAAGTLR 238
           P Y+S+++  +++L       +  E P  ++       +L  GLA  G D  ++A G   
Sbjct: 456 PAYISLHRLLRKMLRGSGLPAVSRENPVASDSYEAAVLSLATGLAHSGTDCSQLAQGLGT 515

Query: 239 QMCTVDLGEPLHSLIITGGSIHP 261
             C+  L    H + +    I+P
Sbjct: 516 WTCSSSLYPSKHPITVEINGINP 538


>gi|194097425 hypothetical protein LOC285966 A [Homo sapiens]
          Length = 845

 Score = 29.3 bits (64), Expect = 4.1
 Identities = 19/83 (22%), Positives = 36/83 (43%), Gaps = 6/83 (7%)

Query: 185 PRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEE------TLCVGLARVGADDQKIAAGTLR 238
           P Y+S+++  +++L       +  E P  ++       +L  GLA  G D  ++A G   
Sbjct: 456 PAYISLHRLLRKMLRGSGLPAVSRENPVASDSYEAAVLSLATGLAHSGTDCSQLAQGLGT 515

Query: 239 QMCTVDLGEPLHSLIITGGSIHP 261
             C+  L    H + +    I+P
Sbjct: 516 WTCSSSLYPSKHPITVEINGINP 538


>gi|21362074 testes development-related NYD-SP22 isoform 1 [Homo
           sapiens]
          Length = 262

 Score = 28.5 bits (62), Expect = 7.0
 Identities = 20/86 (23%), Positives = 36/86 (41%), Gaps = 7/86 (8%)

Query: 136 WTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQ 195
           W +TWR E +           +  L       KE  +E  ++G  +  PPR   +N   +
Sbjct: 106 WYNTWRMEPYNSSCCNKYTTYLPRL------PKEARMETAVRGMPLECPPRPERLNAYER 159

Query: 196 QLLEIVQNQRIRGEE-PAVTEETLCV 220
           +++  + N   R ++ P +T    CV
Sbjct: 160 EVMVNMLNSLSRNQQLPRITPRCGCV 185


>gi|225543215 antigen identified by monoclonal antibody Ki-67 isoform
            2 [Homo sapiens]
          Length = 2896

 Score = 28.1 bits (61), Expect = 9.2
 Identities = 20/88 (22%), Positives = 41/88 (46%), Gaps = 6/88 (6%)

Query: 166  KVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIV--QNQRIRGEEPAVTEETLCVGLA 223
            K K Q+LE+L   +++++   +   +    +  ++    +Q    + PA ++  L   L 
Sbjct: 1219 KEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLG 1278

Query: 224  RVGADDQKIAAGTLRQMCTVDLGEPLHS 251
            +VG  ++ +A G L Q      GE  H+
Sbjct: 1279 KVGVKEELLAVGKLTQTS----GETTHT 1302


>gi|103472005 antigen identified by monoclonal antibody Ki-67 isoform
            1 [Homo sapiens]
          Length = 3256

 Score = 28.1 bits (61), Expect = 9.2
 Identities = 20/88 (22%), Positives = 41/88 (46%), Gaps = 6/88 (6%)

Query: 166  KVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIV--QNQRIRGEEPAVTEETLCVGLA 223
            K K Q+LE+L   +++++   +   +    +  ++    +Q    + PA ++  L   L 
Sbjct: 1579 KEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLG 1638

Query: 224  RVGADDQKIAAGTLRQMCTVDLGEPLHS 251
            +VG  ++ +A G L Q      GE  H+
Sbjct: 1639 KVGVKEELLAVGKLTQTS----GETTHT 1662


>gi|83776596 CaM kinase-like vesicle-associated [Homo sapiens]
          Length = 501

 Score = 28.1 bits (61), Expect = 9.2
 Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 17/87 (19%)

Query: 166 KVKEQSLENLIKG--RKI------YEPPRYMSVNQAAQ----QLLEIVQNQRIRGEEPAV 213
           +V+E   EN  K   RKI      ++ P +  ++QAA+    +L+E+ Q+QRI  EE A+
Sbjct: 223 EVEEDDYENHDKNLFRKILAGDYEFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEE-AI 281

Query: 214 TEETLCVGLARVGADDQKIAAGTLRQM 240
           + E     ++   A D+ I  G   Q+
Sbjct: 282 SHE----WISGNAASDKNIKDGVCAQI 304


>gi|62953116 BTB (POZ) domain containing 11 isoform b [Homo sapiens]
          Length = 641

 Score = 28.1 bits (61), Expect = 9.2
 Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 2/48 (4%)

Query: 52  KLVVADREEVEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRAT 99
           KL    R++  +   + L + ++SDV FLV G PF A  H  L+  A+
Sbjct: 437 KLTEIKRKQTSRLDPHFLNNKEMSDVTFLVEGRPFYA--HKVLLFTAS 482


>gi|65786661 BTB (POZ) domain containing 11 isoform a [Homo sapiens]
          Length = 1104

 Score = 28.1 bits (61), Expect = 9.2
 Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 2/48 (4%)

Query: 52  KLVVADREEVEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRAT 99
           KL    R++  +   + L + ++SDV FLV G PF A  H  L+  A+
Sbjct: 900 KLTEIKRKQTSRLDPHFLNNKEMSDVTFLVEGRPFYA--HKVLLFTAS 945


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,860,620
Number of Sequences: 37866
Number of extensions: 399201
Number of successful extensions: 872
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 865
Number of HSP's gapped (non-prelim): 15
length of query: 285
length of database: 18,247,518
effective HSP length: 101
effective length of query: 184
effective length of database: 14,423,052
effective search space: 2653841568
effective search space used: 2653841568
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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