Search of human proteins with 116875846

Search of human proteins with 116875846

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116875846 phosphopantothenoylcysteine synthetase isoform b
[Homo sapiens]
         (138 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116875846 phosphopantothenoylcysteine synthetase isoform b [H...   269   6e-73
gi|116875844 phosphopantothenoylcysteine synthetase isoform a [H...   269   6e-73
gi|217416392 pleckstrin homology domain containing, family H (wi...    29   1.4  
gi|221136939 pre-mRNA processing factor 31 homolog [Homo sapiens]      28   2.4  
gi|4507347 TBP-associated factor 2 [Homo sapiens]                      28   3.1  
gi|156104908 myosin heavy chain 6 [Homo sapiens]                       27   4.1  
gi|146229331 arylsulfatase A isoform a precursor [Homo sapiens]        27   5.4  
gi|146229329 arylsulfatase A isoform a precursor [Homo sapiens]        27   5.4  
gi|146229324 arylsulfatase A isoform a precursor [Homo sapiens]        27   5.4  
gi|6005990 arylsulfatase A isoform a precursor [Homo sapiens]          27   5.4  
gi|40068061 centromere protein Q [Homo sapiens]                        27   5.4  
gi|62988361 absent in melanoma 1 [Homo sapiens]                        26   9.2  

>gi|116875846 phosphopantothenoylcysteine synthetase isoform b [Homo
           sapiens]
          Length = 138

 Score =  269 bits (687), Expect = 6e-73
 Identities = 138/138 (100%), Positives = 138/138 (100%)

Query: 1   MFYLAAAVSDFYVPVSEMPEHKIQSSGGPLQITMKMVPKLLSPLVKDWAPKAFIISFKLE 60
           MFYLAAAVSDFYVPVSEMPEHKIQSSGGPLQITMKMVPKLLSPLVKDWAPKAFIISFKLE
Sbjct: 1   MFYLAAAVSDFYVPVSEMPEHKIQSSGGPLQITMKMVPKLLSPLVKDWAPKAFIISFKLE 60

Query: 61  TDPAIVINRARKALEIYQHQVVVANILESRQSFVFIVTKDSETKLLLSEEEIEKGVEIEE 120
           TDPAIVINRARKALEIYQHQVVVANILESRQSFVFIVTKDSETKLLLSEEEIEKGVEIEE
Sbjct: 61  TDPAIVINRARKALEIYQHQVVVANILESRQSFVFIVTKDSETKLLLSEEEIEKGVEIEE 120

Query: 121 KIVDNLQSRHTAFIGDRN 138
           KIVDNLQSRHTAFIGDRN
Sbjct: 121 KIVDNLQSRHTAFIGDRN 138


>gi|116875844 phosphopantothenoylcysteine synthetase isoform a [Homo
           sapiens]
          Length = 311

 Score =  269 bits (687), Expect = 6e-73
 Identities = 138/138 (100%), Positives = 138/138 (100%)

Query: 1   MFYLAAAVSDFYVPVSEMPEHKIQSSGGPLQITMKMVPKLLSPLVKDWAPKAFIISFKLE 60
           MFYLAAAVSDFYVPVSEMPEHKIQSSGGPLQITMKMVPKLLSPLVKDWAPKAFIISFKLE
Sbjct: 174 MFYLAAAVSDFYVPVSEMPEHKIQSSGGPLQITMKMVPKLLSPLVKDWAPKAFIISFKLE 233

Query: 61  TDPAIVINRARKALEIYQHQVVVANILESRQSFVFIVTKDSETKLLLSEEEIEKGVEIEE 120
           TDPAIVINRARKALEIYQHQVVVANILESRQSFVFIVTKDSETKLLLSEEEIEKGVEIEE
Sbjct: 234 TDPAIVINRARKALEIYQHQVVVANILESRQSFVFIVTKDSETKLLLSEEEIEKGVEIEE 293

Query: 121 KIVDNLQSRHTAFIGDRN 138
           KIVDNLQSRHTAFIGDRN
Sbjct: 294 KIVDNLQSRHTAFIGDRN 311


>gi|217416392 pleckstrin homology domain containing, family H (with
           MyTH4 domain) member 2 [Homo sapiens]
          Length = 1493

 Score = 28.9 bits (63), Expect = 1.4
 Identities = 16/74 (21%), Positives = 40/74 (54%), Gaps = 4/74 (5%)

Query: 54  IISFKLETDPAIVINRARKALEIYQHQVVVANILESRQSFVFIVTKDSETKLLLSEEEIE 113
           +++ K++     VI+  R+A + +Q       ++E +     I T +SET+L    +++E
Sbjct: 37  LLAEKMQQLERQVIDAERQAEKAFQQ----VQVMEDKLKAANIQTSESETRLYNKCQDLE 92

Query: 114 KGVEIEEKIVDNLQ 127
             ++ ++ ++ NL+
Sbjct: 93  SLIQEKDDVIQNLE 106


>gi|221136939 pre-mRNA processing factor 31 homolog [Homo sapiens]
          Length = 499

 Score = 28.1 bits (61), Expect = 2.4
 Identities = 27/131 (20%), Positives = 55/131 (41%), Gaps = 3/131 (2%)

Query: 6   AAVSDFYVPVSEMPEHKIQSSGGPLQITMKMVPKLLSPLVKDWAPKAFIISFKLETDPAI 65
           A  S+   PV   PE+++      L + ++    ++   ++D   K F     L  +   
Sbjct: 75  AKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSKRFPELESLVPNALD 134

Query: 66  VINRARK---ALEIYQHQVVVANILESRQSFVFIVTKDSETKLLLSEEEIEKGVEIEEKI 122
            I   ++   +L+  ++   +  IL +    V  VT  +     LSEEE+E+  E  +  
Sbjct: 135 YIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLSEEELERLEEACDMA 194

Query: 123 VDNLQSRHTAF 133
           ++   S+H  +
Sbjct: 195 LELNASKHRIY 205


>gi|4507347 TBP-associated factor 2 [Homo sapiens]
          Length = 1199

 Score = 27.7 bits (60), Expect = 3.1
 Identities = 16/61 (26%), Positives = 28/61 (45%), Gaps = 4/61 (6%)

Query: 16  SEMPEHKIQSSGGPLQITMKMVPKLLSPLVKDWAPKAFIISFKLETDPAIVINRARKALE 75
           S M    + S+ G L+    +  K + PL+K W  ++ ++ F      +   NR R  LE
Sbjct: 490 SHMWSQMLVSTSGFLKSISNVSGKDIQPLIKQWVDQSGVVKFY----GSFAFNRKRNVLE 545

Query: 76  I 76
           +
Sbjct: 546 L 546


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score = 27.3 bits (59), Expect = 4.1
 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 8/81 (9%)

Query: 58   KLETDPAIVINRARKALEIYQHQVVVANILESRQSFVFIVTKDSETKLLLSEEEIEKGVE 117
            KLE   A+    A  +LE  + +++ A  LE  Q     +  + E KL   +EE+E+   
Sbjct: 1539 KLELQSAL--EEAEASLEHEEGKILRAQ-LEFNQ-----IKAEIERKLAEKDEEMEQAKR 1590

Query: 118  IEEKIVDNLQSRHTAFIGDRN 138
              +++VD+LQ+   A    RN
Sbjct: 1591 NHQRVVDSLQTSLDAETRSRN 1611


>gi|146229331 arylsulfatase A isoform a precursor [Homo sapiens]
          Length = 507

 Score = 26.9 bits (58), Expect = 5.4
 Identities = 15/42 (35%), Positives = 20/42 (47%)

Query: 9   SDFYVPVSEMPEHKIQSSGGPLQITMKMVPKLLSPLVKDWAP 50
           +DFYVPVS     +     G L + M M P +L P  +   P
Sbjct: 60  TDFYVPVSLCTPSRAALLTGRLPVRMGMYPGVLVPSSRGGLP 101


>gi|146229329 arylsulfatase A isoform a precursor [Homo sapiens]
          Length = 507

 Score = 26.9 bits (58), Expect = 5.4
 Identities = 15/42 (35%), Positives = 20/42 (47%)

Query: 9   SDFYVPVSEMPEHKIQSSGGPLQITMKMVPKLLSPLVKDWAP 50
           +DFYVPVS     +     G L + M M P +L P  +   P
Sbjct: 60  TDFYVPVSLCTPSRAALLTGRLPVRMGMYPGVLVPSSRGGLP 101


>gi|146229324 arylsulfatase A isoform a precursor [Homo sapiens]
          Length = 507

 Score = 26.9 bits (58), Expect = 5.4
 Identities = 15/42 (35%), Positives = 20/42 (47%)

Query: 9   SDFYVPVSEMPEHKIQSSGGPLQITMKMVPKLLSPLVKDWAP 50
           +DFYVPVS     +     G L + M M P +L P  +   P
Sbjct: 60  TDFYVPVSLCTPSRAALLTGRLPVRMGMYPGVLVPSSRGGLP 101


>gi|6005990 arylsulfatase A isoform a precursor [Homo sapiens]
          Length = 507

 Score = 26.9 bits (58), Expect = 5.4
 Identities = 15/42 (35%), Positives = 20/42 (47%)

Query: 9   SDFYVPVSEMPEHKIQSSGGPLQITMKMVPKLLSPLVKDWAP 50
           +DFYVPVS     +     G L + M M P +L P  +   P
Sbjct: 60  TDFYVPVSLCTPSRAALLTGRLPVRMGMYPGVLVPSSRGGLP 101


>gi|40068061 centromere protein Q [Homo sapiens]
          Length = 268

 Score = 26.9 bits (58), Expect = 5.4
 Identities = 14/30 (46%), Positives = 19/30 (63%)

Query: 99  KDSETKLLLSEEEIEKGVEIEEKIVDNLQS 128
           K +E  L L +EEI+K VE  E +  N+QS
Sbjct: 149 KANEEGLALLQEEIDKMVETTELMTGNIQS 178


>gi|62988361 absent in melanoma 1 [Homo sapiens]
          Length = 1723

 Score = 26.2 bits (56), Expect = 9.2
 Identities = 18/46 (39%), Positives = 27/46 (58%), Gaps = 2/46 (4%)

Query: 67  INRARKALEIYQHQVVVANILESRQSFVFIVTKDSETKLLLSEEEI 112
           +N A+KA E+ Q +  V  +  S Q+ V +     ETK+ +SEEEI
Sbjct: 309 LNLAKKAKEMEQPEKKV--MPNSPQNGVLVKETAIETKVTVSEEEI 352


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.369 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,588,098
Number of Sequences: 37866
Number of extensions: 168982
Number of successful extensions: 558
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 549
Number of HSP's gapped (non-prelim): 12
length of query: 138
length of database: 18,247,518
effective HSP length: 91
effective length of query: 47
effective length of database: 14,801,712
effective search space: 695680464
effective search space used: 695680464
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.