Search of human proteins with 116812595

Search of human proteins with 116812595

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116812595 3'(2'), 5'-bisphosphate nucleotidase 1 [Homo
sapiens]
         (308 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116812595 3'(2'), 5'-bisphosphate nucleotidase 1 [Homo sapiens]    615   e-176
gi|157388900 inositol monophosphatase domain containing 1 [Homo ...   104   9e-23
gi|193083155 inositol polyphosphate-1-phosphatase [Homo sapiens]       80   3e-15
gi|4504703 inositol polyphosphate-1-phosphatase [Homo sapiens]         80   3e-15
gi|7657236 inositol(myo)-1(or 4)-monophosphatase 2 [Homo sapiens]      57   2e-08
gi|221625487 inositol(myo)-1(or 4)-monophosphatase 1 isoform 2 [...    52   5e-07
gi|5031789 inositol(myo)-1(or 4)-monophosphatase 1 isoform 1 [Ho...    52   5e-07
gi|221625507 inositol(myo)-1(or 4)-monophosphatase 1 isoform 3 [...    44   2e-04
gi|50980309 UTP15, U3 small nucleolar ribonucleoprotein, homolog...    32   0.54 
gi|87298939 hypothetical protein LOC131831 [Homo sapiens]              29   4.6  
gi|47578117 DEP domain containing 2 isoform b [Homo sapiens]           28   7.9  
gi|47578115 DEP domain containing 2 isoform a [Homo sapiens]           28   7.9  

>gi|116812595 3'(2'), 5'-bisphosphate nucleotidase 1 [Homo sapiens]
          Length = 308

 Score =  615 bits (1586), Expect = e-176
 Identities = 308/308 (100%), Positives = 308/308 (100%)

Query: 1   MASSNTVLMRLVASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICS 60
           MASSNTVLMRLVASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICS
Sbjct: 1   MASSNTVLMRLVASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICS 60

Query: 61  SLARKFPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLD 120
           SLARKFPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLD
Sbjct: 61  SLARKFPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLD 120

Query: 121 GTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGF 180
           GTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGF
Sbjct: 121 GTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGF 180

Query: 181 QLKEVPAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFAS 240
           QLKEVPAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFAS
Sbjct: 181 QLKEVPAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFAS 240

Query: 241 PGCKKWDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSAGVLATLRNYDYYASRVPE 300
           PGCKKWDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSAGVLATLRNYDYYASRVPE
Sbjct: 241 PGCKKWDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSAGVLATLRNYDYYASRVPE 300

Query: 301 SIKNALVP 308
           SIKNALVP
Sbjct: 301 SIKNALVP 308


>gi|157388900 inositol monophosphatase domain containing 1 [Homo
           sapiens]
          Length = 359

 Score =  104 bits (260), Expect = 9e-23
 Identities = 90/312 (28%), Positives = 142/312 (45%), Gaps = 28/312 (8%)

Query: 2   ASSNTVLMR-LVASAYSIAQKAGMIVRRVIAEGDLGIVEK----TCATDLQTKADRLAQM 56
           A   TV +R ++A +   A + G  VRRV     L    K      A D  T  D L+  
Sbjct: 56  ADGGTVDLREMLAVSVLAAVRGGDEVRRVRESNVLHEKSKGKTREGAEDKMTSGDVLSNR 115

Query: 57  SICSSLARKFPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWV 116
            +   L   FP + I  EE + + + +  L +    E+ILK+    +   +  E + VW+
Sbjct: 116 KMFYLLKTAFPSVQINTEEHVDAADQEVILWDHKIPEDILKEVTTPK--EVPAESVTVWI 173

Query: 117 DPLDGTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLG 176
           DPLD T+EYTE L   VT ++ +A  GK + GVI++P+  Y          T W ++  G
Sbjct: 174 DPLDATQEYTEDLRKYVTTMVCVAVNGKPMLGVIHKPFSEY----------TAWAMVDGG 223

Query: 177 AFGFQLKEVPAGKHIITTTRSHSNKLVTDCVAAM-NPDAVLRVGGAGNKIIQLI------ 229
           +              I  +RSHS  +    +    N   ++  GGAG K++ L+      
Sbjct: 224 SNVKARSSYNEKTPRIVVSRSHSGMVKQVALQTFGNQTTIIPAGGAGYKVLALLDVPDKS 283

Query: 230 EGKASAYVFASPGCKKWDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSAGVLATLR 289
           + KA  Y+  +   KKWD CA   IL A+GG +T + G  + Y          G+LA++R
Sbjct: 284 QEKADLYIHVT-YIKKWDICAGNAILKALGGHMTTLSGEEISY--TGSDGIEGGLLASIR 340

Query: 290 -NYDYYASRVPE 300
            N+     ++P+
Sbjct: 341 MNHQALVRKLPD 352


>gi|193083155 inositol polyphosphate-1-phosphatase [Homo sapiens]
          Length = 399

 Score = 79.7 bits (195), Expect = 3e-15
 Identities = 75/306 (24%), Positives = 119/306 (38%), Gaps = 72/306 (23%)

Query: 29  VIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKL--TIIGEE----------- 75
           +I E   G   K  A D +T AD L Q  I  ++  KFP L   I GEE           
Sbjct: 32  LIEEKKEGEKNKKFAVDFKTLADVLVQEVIKQNMENKFPGLEKNIFGEESNEFTNDWGEK 91

Query: 76  -------------DLPSEEVDQELIEDSQWEEILKQPCP-------SQYSAIKEEDLVVW 115
                        +L S+ ++   +       ++ Q          S    + ++ L +W
Sbjct: 92  ITLRLCSTEEETAELLSKVLNGNKVASEALARVVHQDVAFTDPTLDSTEINVPQDILGIW 151

Query: 116 VDPLDGTKEYTEGLLDN-------------VTVLIGI--AYEGKAIAGVINQPYYNYEAG 160
           VDP+D T +Y +G  D              VT+LIG+     G  + GVINQP+ + +  
Sbjct: 152 VDPIDSTYQYIKGSADIKSNQGIFPCGLQCVTILIGVYDIQTGVPLMGVINQPFVSRDPN 211

Query: 161 PDAVLGRTIWGVLGLGA---------------------FGFQLKEVPAGKHIITTTRSHS 199
                G+  WG+  +G                       G +    P+   +I+T+   +
Sbjct: 212 TLRWKGQCYWGLSYMGTNMHSLQLTISRRNGSETHTGNTGSEAAFSPSFSAVISTSEKET 271

Query: 200 NKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGCKKWDTCAPEVILHAVG 259
            K     V     D +    GAG K + +++G    Y+F+     KWD+CA   IL A+G
Sbjct: 272 IKAALSRVCG---DRIFGAAGAGYKSLCVVQGLVDIYIFSEDTTFKWDSCAAHAILRAMG 328

Query: 260 GKLTDI 265
           G + D+
Sbjct: 329 GGIVDL 334


>gi|4504703 inositol polyphosphate-1-phosphatase [Homo sapiens]
          Length = 399

 Score = 79.7 bits (195), Expect = 3e-15
 Identities = 75/306 (24%), Positives = 119/306 (38%), Gaps = 72/306 (23%)

Query: 29  VIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKL--TIIGEE----------- 75
           +I E   G   K  A D +T AD L Q  I  ++  KFP L   I GEE           
Sbjct: 32  LIEEKKEGEKNKKFAVDFKTLADVLVQEVIKQNMENKFPGLEKNIFGEESNEFTNDWGEK 91

Query: 76  -------------DLPSEEVDQELIEDSQWEEILKQPCP-------SQYSAIKEEDLVVW 115
                        +L S+ ++   +       ++ Q          S    + ++ L +W
Sbjct: 92  ITLRLCSTEEETAELLSKVLNGNKVASEALARVVHQDVAFTDPTLDSTEINVPQDILGIW 151

Query: 116 VDPLDGTKEYTEGLLDN-------------VTVLIGI--AYEGKAIAGVINQPYYNYEAG 160
           VDP+D T +Y +G  D              VT+LIG+     G  + GVINQP+ + +  
Sbjct: 152 VDPIDSTYQYIKGSADIKSNQGIFPCGLQCVTILIGVYDIQTGVPLMGVINQPFVSRDPN 211

Query: 161 PDAVLGRTIWGVLGLGA---------------------FGFQLKEVPAGKHIITTTRSHS 199
                G+  WG+  +G                       G +    P+   +I+T+   +
Sbjct: 212 TLRWKGQCYWGLSYMGTNMHSLQLTISRRNGSETHTGNTGSEAAFSPSFSAVISTSEKET 271

Query: 200 NKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGCKKWDTCAPEVILHAVG 259
            K     V     D +    GAG K + +++G    Y+F+     KWD+CA   IL A+G
Sbjct: 272 IKAALSRVCG---DRIFGAAGAGYKSLCVVQGLVDIYIFSEDTTFKWDSCAAHAILRAMG 328

Query: 260 GKLTDI 265
           G + D+
Sbjct: 329 GGIVDL 334


>gi|7657236 inositol(myo)-1(or 4)-monophosphatase 2 [Homo sapiens]
          Length = 288

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 74/271 (27%), Positives = 102/271 (37%), Gaps = 52/271 (19%)

Query: 14  SAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIG 73
           +A  +A +AG I+R+ + E +  +  KT A DL T+ D L +  I S L  +FP    I 
Sbjct: 22  AAVQLALRAGQIIRKALTE-EKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIA 80

Query: 74  EEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWV-DPLDGTKEYTEGLLDN 132
           EE   S                    C   +S         W+ DP+DGT  +       
Sbjct: 81  EEAAASGA-----------------KCVLTHSP-------TWIIDPIDGTCNFVHRF-PT 115

Query: 133 VTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAF--GFQLK---EVPA 187
           V V IG A   +   GVI   Y+  E        R   G  G GAF  G +L+   E   
Sbjct: 116 VAVSIGFAVRQELEFGVI---YHCTEE-------RLYTGRRGRGAFCNGQRLRVSGETDL 165

Query: 188 GKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKII--------QLIEGKASAYVFA 239
            K ++ T         T  +   N + +L     G ++I         L  G A AY   
Sbjct: 166 SKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQF 225

Query: 240 SPGCKKWDTCAPEVILHAVGGKLTDIHGNVL 270
              C  WD  A  VI+   GG + D  G  L
Sbjct: 226 GLHC--WDLAAATVIIREAGGIVIDTSGGPL 254


>gi|221625487 inositol(myo)-1(or 4)-monophosphatase 1 isoform 2
           [Homo sapiens]
          Length = 336

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 64/266 (24%), Positives = 103/266 (38%), Gaps = 50/266 (18%)

Query: 15  AYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGE 74
           A ++A++AG +V   I + ++ ++ K+   DL T  D+  +  + SS+  K+P  + IGE
Sbjct: 71  AVTLARQAGEVVCEAI-KNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGE 129

Query: 75  EDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVT 134
           E + + E    L ++  W                       +DP+DGT  +       V 
Sbjct: 130 ESVAAGE-KSILTDNPTW----------------------IIDPIDGTTNFVH-RFPFVA 165

Query: 135 VLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAF--GFQL---KEVPAGK 189
           V IG A   K   GV+             V G+      G GAF  G +L   ++    K
Sbjct: 166 VSIGFAVNKKIEFGVVY----------SCVEGKMYTARKGKGAFCNGQKLQVSQQEDITK 215

Query: 190 HIITTTRSHSNKLVTDCVAAMNPD--------AVLRVGGAGNKIIQLIEGKASAYVFASP 241
            ++ T    S    T  +   N +         +  VG A   +  +  G A AY     
Sbjct: 216 SLLVTELGSSRTPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGI 275

Query: 242 GCKKWDTCAPEVILHAVGGKLTDIHG 267
            C  WD     +I+   GG L D+ G
Sbjct: 276 HC--WDVAGAGIIVTEAGGVLMDVTG 299


>gi|5031789 inositol(myo)-1(or 4)-monophosphatase 1 isoform 1 [Homo
           sapiens]
          Length = 277

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 64/266 (24%), Positives = 103/266 (38%), Gaps = 50/266 (18%)

Query: 15  AYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGE 74
           A ++A++AG +V   I + ++ ++ K+   DL T  D+  +  + SS+  K+P  + IGE
Sbjct: 12  AVTLARQAGEVVCEAI-KNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGE 70

Query: 75  EDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVT 134
           E + + E    L ++  W                       +DP+DGT  +       V 
Sbjct: 71  ESVAAGE-KSILTDNPTW----------------------IIDPIDGTTNFVH-RFPFVA 106

Query: 135 VLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAF--GFQL---KEVPAGK 189
           V IG A   K   GV+             V G+      G GAF  G +L   ++    K
Sbjct: 107 VSIGFAVNKKIEFGVVY----------SCVEGKMYTARKGKGAFCNGQKLQVSQQEDITK 156

Query: 190 HIITTTRSHSNKLVTDCVAAMNPD--------AVLRVGGAGNKIIQLIEGKASAYVFASP 241
            ++ T    S    T  +   N +         +  VG A   +  +  G A AY     
Sbjct: 157 SLLVTELGSSRTPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGI 216

Query: 242 GCKKWDTCAPEVILHAVGGKLTDIHG 267
            C  WD     +I+   GG L D+ G
Sbjct: 217 HC--WDVAGAGIIVTEAGGVLMDVTG 240


>gi|221625507 inositol(myo)-1(or 4)-monophosphatase 1 isoform 3
           [Homo sapiens]
          Length = 198

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 35/136 (25%), Positives = 60/136 (44%), Gaps = 25/136 (18%)

Query: 15  AYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGE 74
           A ++A++AG +V   I + ++ ++ K+   DL T  D+  +  + SS+  K+P  + IGE
Sbjct: 12  AVTLARQAGEVVCEAI-KNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGE 70

Query: 75  EDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVT 134
           E + + E    L ++  W                       +DP+DGT  +       V 
Sbjct: 71  ESVAAGE-KSILTDNPTW----------------------IIDPIDGTTNFVH-RFPFVA 106

Query: 135 VLIGIAYEGKAIAGVI 150
           V IG A   K   GV+
Sbjct: 107 VSIGFAVNKKIEFGVV 122


>gi|50980309 UTP15, U3 small nucleolar ribonucleoprotein, homolog
           [Homo sapiens]
          Length = 518

 Score = 32.3 bits (72), Expect = 0.54
 Identities = 28/120 (23%), Positives = 57/120 (47%), Gaps = 10/120 (8%)

Query: 172 VLGLGAFGFQLKEVPAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEG 231
           V G   +  +L ++P  K I+T  + HS+ +   C + +NPD  L + G+ +  +++ + 
Sbjct: 138 VSGADDYTVKLWDIPNSKEILTF-KEHSDYVRCGCASKLNPD--LFITGSYDHTVKMFDA 194

Query: 232 KASAYVFASPGCKKWDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSAGVLATLRNY 291
           + S  V +    +  ++    V+L   GG L    G   +Y K    +    +L +L+N+
Sbjct: 195 RTSESVLSVEHGQPVES----VLLFPSGGLLVSAGG---RYVKVWDMLKGGQLLVSLKNH 247


>gi|87298939 hypothetical protein LOC131831 [Homo sapiens]
          Length = 663

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 17/61 (27%), Positives = 32/61 (52%)

Query: 74  EEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNV 133
           EE+L  EE ++E+ E+ +  E  ++    +   + EE+LV     L+  + ++E  L  V
Sbjct: 22  EEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEEYLWKV 81

Query: 134 T 134
           T
Sbjct: 82  T 82


>gi|47578117 DEP domain containing 2 isoform b [Homo sapiens]
          Length = 979

 Score = 28.5 bits (62), Expect = 7.9
 Identities = 12/31 (38%), Positives = 19/31 (61%)

Query: 119 LDGTKEYTEGLLDNVTVLIGIAYEGKAIAGV 149
           +DG KE+    +DNV +  G+ YE  + AG+
Sbjct: 801 IDGKKEHVSLTVDNVHLEYGVVYEYDSTAGI 831


>gi|47578115 DEP domain containing 2 isoform a [Homo sapiens]
          Length = 1606

 Score = 28.5 bits (62), Expect = 7.9
 Identities = 12/31 (38%), Positives = 19/31 (61%)

Query: 119 LDGTKEYTEGLLDNVTVLIGIAYEGKAIAGV 149
           +DG KE+    +DNV +  G+ YE  + AG+
Sbjct: 801 IDGKKEHVSLTVDNVHLEYGVVYEYDSTAGI 831


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,542,731
Number of Sequences: 37866
Number of extensions: 523030
Number of successful extensions: 1215
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1196
Number of HSP's gapped (non-prelim): 12
length of query: 308
length of database: 18,247,518
effective HSP length: 102
effective length of query: 206
effective length of database: 14,385,186
effective search space: 2963348316
effective search space used: 2963348316
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.