Guide to the Human Genome
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Search of human proteins with 22749165

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22749165 ATPase, H+ transporting, lysosomal 38kDa, V0
subunit D2 [Homo sapiens]
         (350 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22749165 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit...   713   0.0  
gi|19913432 ATPase, H+ transporting, lysosomal, V0 subunit d1 [H...   496   e-140
gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]             30   2.5  
gi|38524612 tripartite motif-containing 74 [Homo sapiens]              30   2.5  
gi|65285121 tripartite motif-containing 73 [Homo sapiens]              30   2.5  
gi|46370057 ring finger protein 216 isoform b [Homo sapiens]           28   9.4  
gi|46358403 ring finger protein 216 isoform a [Homo sapiens]           28   9.4  

>gi|22749165 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit D2
           [Homo sapiens]
          Length = 350

 Score =  713 bits (1840), Expect = 0.0
 Identities = 350/350 (100%), Positives = 350/350 (100%)

Query: 1   MLEGAELYFNVDHGYLEGLVRGCKASLLTQQDYINLVQCETLEDLKIHLQTTDYGNFLAN 60
           MLEGAELYFNVDHGYLEGLVRGCKASLLTQQDYINLVQCETLEDLKIHLQTTDYGNFLAN
Sbjct: 1   MLEGAELYFNVDHGYLEGLVRGCKASLLTQQDYINLVQCETLEDLKIHLQTTDYGNFLAN 60

Query: 61  HTNPLTVSKIDTEMRKRLCGEFEYFRNHSLEPLSTFLTYMTCSYMIDNVILLMNGALQKK 120
           HTNPLTVSKIDTEMRKRLCGEFEYFRNHSLEPLSTFLTYMTCSYMIDNVILLMNGALQKK
Sbjct: 61  HTNPLTVSKIDTEMRKRLCGEFEYFRNHSLEPLSTFLTYMTCSYMIDNVILLMNGALQKK 120

Query: 121 SVKEILGKCHPLGRFTEMEAVNIAETPSDLFNAILIETPLAPFFQDCMSENALDELNIEL 180
           SVKEILGKCHPLGRFTEMEAVNIAETPSDLFNAILIETPLAPFFQDCMSENALDELNIEL
Sbjct: 121 SVKEILGKCHPLGRFTEMEAVNIAETPSDLFNAILIETPLAPFFQDCMSENALDELNIEL 180

Query: 181 LRNKLYKSYLEAFYKFCKNHGDVTAEVMCPILEFEADRRAFIITLNSFGTELSKEDRETL 240
           LRNKLYKSYLEAFYKFCKNHGDVTAEVMCPILEFEADRRAFIITLNSFGTELSKEDRETL
Sbjct: 181 LRNKLYKSYLEAFYKFCKNHGDVTAEVMCPILEFEADRRAFIITLNSFGTELSKEDRETL 240

Query: 241 YPTFGKLYPEGLRLLAQAEDFDQMKNVADHYGVYKPLFEAVGGSGGKTLEDVFYEREVQM 300
           YPTFGKLYPEGLRLLAQAEDFDQMKNVADHYGVYKPLFEAVGGSGGKTLEDVFYEREVQM
Sbjct: 241 YPTFGKLYPEGLRLLAQAEDFDQMKNVADHYGVYKPLFEAVGGSGGKTLEDVFYEREVQM 300

Query: 301 NVLAFNRQFHYGVFYAYVKLKEQEIRNIVWIAECISQRHRTKINSYIPIL 350
           NVLAFNRQFHYGVFYAYVKLKEQEIRNIVWIAECISQRHRTKINSYIPIL
Sbjct: 301 NVLAFNRQFHYGVFYAYVKLKEQEIRNIVWIAECISQRHRTKINSYIPIL 350


>gi|19913432 ATPase, H+ transporting, lysosomal, V0 subunit d1 [Homo
           sapiens]
          Length = 351

 Score =  496 bits (1276), Expect = e-140
 Identities = 236/345 (68%), Positives = 292/345 (84%), Gaps = 1/345 (0%)

Query: 6   ELYFNVDHGYLEGLVRGCKASLLTQQDYINLVQCETLEDLKIHLQTTDYGNFLANHTNPL 65
           ELYFNVD+GYLEGLVRG KA +L+Q DY+NLVQCETLEDLK+HLQ+TDYGNFLAN  +PL
Sbjct: 6   ELYFNVDNGYLEGLVRGLKAGVLSQADYLNLVQCETLEDLKLHLQSTDYGNFLANEASPL 65

Query: 66  TVSKIDTEMRKRLCGEFEYFRNHSLEPLSTFLTYMTCSYMIDNVILLMNGALQKKSVKEI 125
           TVS ID  +++++  EF + RNH+ EPL++FL ++T SYMIDNVILL+ G L ++S+ E+
Sbjct: 66  TVSVIDDRLKEKMVVEFRHMRNHAYEPLASFLDFITYSYMIDNVILLITGTLHQRSIAEL 125

Query: 126 LGKCHPLGRFTEMEAVNIAETPSDLFNAILIETPLAPFFQDCMSENALDELNIELLRNKL 185
           + KCHPLG F +MEAVNIA+TP++L+NAIL++TPLA FFQDC+SE  LDE+NIE++RN L
Sbjct: 126 VPKCHPLGSFEQMEAVNIAQTPAELYNAILVDTPLAAFFQDCISEQDLDEMNIEIIRNTL 185

Query: 186 YKSYLEAFYKFCKNHGDVTAEVMCPILEFEADRRAFIITLNSFGTELSKEDRETLYPTFG 245
           YK+YLE+FYKFC   G  TA+ MCPILEFEADRRAFIIT+NSFGTELSKEDR  L+P  G
Sbjct: 186 YKAYLESFYKFCTLLGGTTADAMCPILEFEADRRAFIITINSFGTELSKEDRAKLFPHCG 245

Query: 246 KLYPEGLRLLAQAEDFDQMKNVADHYGVYKPLFEAVGGS-GGKTLEDVFYEREVQMNVLA 304
           +LYPEGL  LA+A+D++Q+KNVAD+Y  YK LFE  G + G KTLED F+E EV++N LA
Sbjct: 246 RLYPEGLAQLARADDYEQVKNVADYYPEYKLLFEGAGSNPGDKTLEDRFFEHEVKLNKLA 305

Query: 305 FNRQFHYGVFYAYVKLKEQEIRNIVWIAECISQRHRTKINSYIPI 349
           F  QFH+GVFYA+VKLKEQE RNIVWIAECI+QRHR KI++YIPI
Sbjct: 306 FLNQFHFGVFYAFVKLKEQECRNIVWIAECIAQRHRAKIDNYIPI 350


>gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]
          Length = 4624

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 7/77 (9%)

Query: 2   LEGAELYFNVDHGYL---EGLVRGCKASLLTQQDYINLVQCETLEDLKIHLQTTDYGNFL 58
           LEG +   N+   +L   EG V     +  + ++ +NL +C+ LE LK   + TDY   L
Sbjct: 186 LEGLQDAANIRQEFLSSLEGFVNVLSGAQESLKEKVNLRKCDILE-LKTLKEPTDY---L 241

Query: 59  ANHTNPLTVSKIDTEMR 75
               NP T+ KI+  M+
Sbjct: 242 TLANNPETLGKIEDCMK 258


>gi|38524612 tripartite motif-containing 74 [Homo sapiens]
          Length = 250

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 7/71 (9%)

Query: 60  NHTNPLTV-SKIDTEMRKRLCGEFEYFRNHSLEPLSTFLTYMTCSYMIDNVILLMNGALQ 118
           +H NPL++  + D E+   LCG     ++H + P+ST      CS M + +  L +   Q
Sbjct: 91  HHRNPLSLFCEKDQELICGLCGLLGSHQHHPVTPVST-----VCSRMKEELAALFSELKQ 145

Query: 119 -KKSVKEILGK 128
            +K V E++ K
Sbjct: 146 EQKKVDELIAK 156


>gi|65285121 tripartite motif-containing 73 [Homo sapiens]
          Length = 250

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 7/71 (9%)

Query: 60  NHTNPLTV-SKIDTEMRKRLCGEFEYFRNHSLEPLSTFLTYMTCSYMIDNVILLMNGALQ 118
           +H NPL++  + D E+   LCG     ++H + P+ST      CS M + +  L +   Q
Sbjct: 91  HHRNPLSLFCEKDQELICGLCGLLGSHQHHPVTPVST-----VCSRMKEELAALFSELKQ 145

Query: 119 -KKSVKEILGK 128
            +K V E++ K
Sbjct: 146 EQKKVDELIAK 156


>gi|46370057 ring finger protein 216 isoform b [Homo sapiens]
          Length = 866

 Score = 28.5 bits (62), Expect = 9.4
 Identities = 36/146 (24%), Positives = 61/146 (41%), Gaps = 21/146 (14%)

Query: 130 HPLGRFTEMEAVNIAETPSDLFNAILIETPLAPFFQDCMSENA--LDELNIELLRNK--- 184
           HPLG F + +  +  E P   F    ++    P  ++   + A  +D+  +ELL  +   
Sbjct: 237 HPLGEFEDQQLASDDEEPGPAFP---MQESQEPNLENIWGQEAAEVDQELVELLVKETEA 293

Query: 185 ----LYKSYLEAFYKFCKNHGDVTAEVMCPILEFEAD--RRAFIITLNSFGTELSKEDRE 238
               +   ++E    F KN+ D+   V+C  L    D  +R   I +N   + L+ +D  
Sbjct: 294 RFPDVANGFIEEIIHF-KNYYDL--NVLCNFLLENPDYPKREDRIIINPSSSLLASQDET 350

Query: 239 TL----YPTFGKLYPEGLRLLAQAED 260
            L    +  + KL P   R   QA D
Sbjct: 351 KLPKIDFFDYSKLTPLDQRCFIQAAD 376


>gi|46358403 ring finger protein 216 isoform a [Homo sapiens]
          Length = 923

 Score = 28.5 bits (62), Expect = 9.4
 Identities = 36/146 (24%), Positives = 61/146 (41%), Gaps = 21/146 (14%)

Query: 130 HPLGRFTEMEAVNIAETPSDLFNAILIETPLAPFFQDCMSENA--LDELNIELLRNK--- 184
           HPLG F + +  +  E P   F    ++    P  ++   + A  +D+  +ELL  +   
Sbjct: 294 HPLGEFEDQQLASDDEEPGPAFP---MQESQEPNLENIWGQEAAEVDQELVELLVKETEA 350

Query: 185 ----LYKSYLEAFYKFCKNHGDVTAEVMCPILEFEAD--RRAFIITLNSFGTELSKEDRE 238
               +   ++E    F KN+ D+   V+C  L    D  +R   I +N   + L+ +D  
Sbjct: 351 RFPDVANGFIEEIIHF-KNYYDL--NVLCNFLLENPDYPKREDRIIINPSSSLLASQDET 407

Query: 239 TL----YPTFGKLYPEGLRLLAQAED 260
            L    +  + KL P   R   QA D
Sbjct: 408 KLPKIDFFDYSKLTPLDQRCFIQAAD 433


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.139    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,218,189
Number of Sequences: 37866
Number of extensions: 496174
Number of successful extensions: 919
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 916
Number of HSP's gapped (non-prelim): 7
length of query: 350
length of database: 18,247,518
effective HSP length: 103
effective length of query: 247
effective length of database: 14,347,320
effective search space: 3543788040
effective search space used: 3543788040
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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