Search of human proteins with 22749067

Search of human proteins with 22749067

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22749067 HORMA domain containing 2 [Homo sapiens]
         (307 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22749067 HORMA domain containing 2 [Homo sapiens]                  623   e-179
gi|31542507 HORMA domain containing 1 [Homo sapiens]                  270   1e-72
gi|14195601 protein phosphatase 1, regulatory (inhibitor) subuni...    31   1.6  
gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit...    31   1.6  
gi|54792745 SH2 domain containing 1B [Homo sapiens]                    30   2.1  
gi|194473995 zinc finger protein 195 isoform 2 [Homo sapiens]          30   2.7  
gi|194473688 zinc finger protein 195 isoform 1 [Homo sapiens]          30   2.7  
gi|116014332 zinc finger protein 195 isoform 3 [Homo sapiens]          30   2.7  
gi|238624099 SET domain, bifurcated 2 isoform b [Homo sapiens]         29   6.0  
gi|238624095 SET domain, bifurcated 2 isoform a [Homo sapiens]         29   6.0  
gi|20070228 nucleobindin 1 [Homo sapiens]                              28   7.8  

>gi|22749067 HORMA domain containing 2 [Homo sapiens]
          Length = 307

 Score =  623 bits (1606), Expect = e-179
 Identities = 307/307 (100%), Positives = 307/307 (100%)

Query: 1   MATAQLSHCITIHKASKETVFPSQITNEHESLKMVKKLFATSISCITYLRGLFPESSYGE 60
           MATAQLSHCITIHKASKETVFPSQITNEHESLKMVKKLFATSISCITYLRGLFPESSYGE
Sbjct: 1   MATAQLSHCITIHKASKETVFPSQITNEHESLKMVKKLFATSISCITYLRGLFPESSYGE 60

Query: 61  RHLDDLSLKILREDKKCPGSLHIIRWIQGCFDALEKRYLRMAVLTLYTDPMGSEKVTEMY 120
           RHLDDLSLKILREDKKCPGSLHIIRWIQGCFDALEKRYLRMAVLTLYTDPMGSEKVTEMY
Sbjct: 61  RHLDDLSLKILREDKKCPGSLHIIRWIQGCFDALEKRYLRMAVLTLYTDPMGSEKVTEMY 120

Query: 121 QFKFKYTKEGATMDFDSHSSSTSFESGTNNEDIKKASVLLIRKLYILMQDLEPLPNNVVL 180
           QFKFKYTKEGATMDFDSHSSSTSFESGTNNEDIKKASVLLIRKLYILMQDLEPLPNNVVL
Sbjct: 121 QFKFKYTKEGATMDFDSHSSSTSFESGTNNEDIKKASVLLIRKLYILMQDLEPLPNNVVL 180

Query: 181 TMKLHYYNAVTPHDYQPLGFKEGVNSHFLLFDKEPINVQVGFVSTGFHSMKVKVMTEATK 240
           TMKLHYYNAVTPHDYQPLGFKEGVNSHFLLFDKEPINVQVGFVSTGFHSMKVKVMTEATK
Sbjct: 181 TMKLHYYNAVTPHDYQPLGFKEGVNSHFLLFDKEPINVQVGFVSTGFHSMKVKVMTEATK 240

Query: 241 VIDLENNLFRENSTTEIAHQGLDCDEEEECNDHIQRMNFVCSQQSSECSRKKRKVSEPVK 300
           VIDLENNLFRENSTTEIAHQGLDCDEEEECNDHIQRMNFVCSQQSSECSRKKRKVSEPVK
Sbjct: 241 VIDLENNLFRENSTTEIAHQGLDCDEEEECNDHIQRMNFVCSQQSSECSRKKRKVSEPVK 300

Query: 301 VFIPNRK 307
           VFIPNRK
Sbjct: 301 VFIPNRK 307


>gi|31542507 HORMA domain containing 1 [Homo sapiens]
          Length = 394

 Score =  270 bits (690), Expect = 1e-72
 Identities = 136/248 (54%), Positives = 180/248 (72%), Gaps = 8/248 (3%)

Query: 1   MATAQLSHCITIHKASKETVFPSQITNEHESLKMVKKLFATSISCITYLRGLFPESSYGE 60
           MATAQL             VFP++I+ EH+SL +VK+L A S+SCITYLRG+FPE +YG 
Sbjct: 1   MATAQLQRT-----PMSALVFPNKISTEHQSLVLVKRLLAVSVSCITYLRGIFPECAYGT 55

Query: 61  RHLDDLSLKILREDKKCPGSLHIIRWIQGCFDALEKRYLRMAVLTLYTDPMGSEKVTEMY 120
           R+LDDL +KILREDK CPGS  +++W+ GC+DAL+K+YLRM VL +YT+P   + ++E Y
Sbjct: 56  RYLDDLCVKILREDKNCPGSTQLVKWMLGCYDALQKKYLRMVVLAVYTNPEDPQTISECY 115

Query: 121 QFKFKYTKEGATMDFDSHSSSTSFESGTNNEDIKKASVLLIRKLYILMQDLEPLPNNVVL 180
           QFKFKYT  G  MDF S + S   ES   + D KKAS+LLIRK+YILMQ+L PLPN+V L
Sbjct: 116 QFKFKYTNNGPLMDFISKNQSN--ESSMLSTDTKKASILLIRKIYILMQNLGPLPNDVCL 173

Query: 181 TMKLHYYNAVTPHDYQPLGFKEGVNSHFLLFDKEPINVQVGFVSTGFHSMKVKVMTEATK 240
           TMKL YY+ VTP DYQP GFK+G +   ++F+ EP+ + VG VST FH  KVKV TE  +
Sbjct: 174 TMKLFYYDEVTPPDYQPPGFKDG-DCEGVIFEGEPMYLNVGEVSTPFHIFKVKVTTERER 232

Query: 241 VIDLENNL 248
           + ++++ +
Sbjct: 233 MENIDSTI 240


>gi|14195601 protein phosphatase 1, regulatory (inhibitor) subunit
           12B isoform b [Homo sapiens]
          Length = 998

 Score = 30.8 bits (68), Expect = 1.6
 Identities = 19/85 (22%), Positives = 41/85 (48%)

Query: 212 DKEPINVQVGFVSTGFHSMKVKVMTEATKVIDLENNLFRENSTTEIAHQGLDCDEEEECN 271
           D+ P + ++G   TG H+M  +V      + D  ++++R +S+  I+    + D+E E  
Sbjct: 432 DESPSSWRLGLRKTGSHNMLSEVANSREPIRDRGSSIYRSSSSPRISALLDNKDKERENK 491

Query: 272 DHIQRMNFVCSQQSSECSRKKRKVS 296
            +I  +       +S+   K+ + S
Sbjct: 492 SYISSLAPRKLNSTSDIEEKENRES 516


>gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit
           12B isoform a [Homo sapiens]
          Length = 982

 Score = 30.8 bits (68), Expect = 1.6
 Identities = 19/85 (22%), Positives = 41/85 (48%)

Query: 212 DKEPINVQVGFVSTGFHSMKVKVMTEATKVIDLENNLFRENSTTEIAHQGLDCDEEEECN 271
           D+ P + ++G   TG H+M  +V      + D  ++++R +S+  I+    + D+E E  
Sbjct: 432 DESPSSWRLGLRKTGSHNMLSEVANSREPIRDRGSSIYRSSSSPRISALLDNKDKERENK 491

Query: 272 DHIQRMNFVCSQQSSECSRKKRKVS 296
            +I  +       +S+   K+ + S
Sbjct: 492 SYISSLAPRKLNSTSDIEEKENRES 516


>gi|54792745 SH2 domain containing 1B [Homo sapiens]
          Length = 132

 Score = 30.4 bits (67), Expect = 2.1
 Identities = 14/32 (43%), Positives = 20/32 (62%)

Query: 185 HYYNAVTPHDYQPLGFKEGVNSHFLLFDKEPI 216
           +Y+  +T  D + L  KEGV+ +FLL D E I
Sbjct: 5   YYHGRLTKQDCETLLLKEGVDGNFLLRDSESI 36


>gi|194473995 zinc finger protein 195 isoform 2 [Homo sapiens]
          Length = 606

 Score = 30.0 bits (66), Expect = 2.7
 Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 5/80 (6%)

Query: 224 STGFHSMKVKVMTEATKVIDLENNLFRENSTTEIAHQGLDCDEEEECNDHIQRMNFVCSQ 283
           S+  HS K+    +  K+ D  +NL R N    I++ G    + +EC    Q ++F+   
Sbjct: 185 SSTTHS-KIFQYNKYVKIFDNFSNLHRRN----ISNTGEKPFKCQECGKSFQMLSFLTEH 239

Query: 284 QSSECSRKKRKVSEPVKVFI 303
           Q     +K +K  E  K FI
Sbjct: 240 QKIHTGKKFQKCGECGKTFI 259


>gi|194473688 zinc finger protein 195 isoform 1 [Homo sapiens]
          Length = 629

 Score = 30.0 bits (66), Expect = 2.7
 Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 5/80 (6%)

Query: 224 STGFHSMKVKVMTEATKVIDLENNLFRENSTTEIAHQGLDCDEEEECNDHIQRMNFVCSQ 283
           S+  HS K+    +  K+ D  +NL R N    I++ G    + +EC    Q ++F+   
Sbjct: 208 SSTTHS-KIFQYNKYVKIFDNFSNLHRRN----ISNTGEKPFKCQECGKSFQMLSFLTEH 262

Query: 284 QSSECSRKKRKVSEPVKVFI 303
           Q     +K +K  E  K FI
Sbjct: 263 QKIHTGKKFQKCGECGKTFI 282


>gi|116014332 zinc finger protein 195 isoform 3 [Homo sapiens]
          Length = 557

 Score = 30.0 bits (66), Expect = 2.7
 Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 5/80 (6%)

Query: 224 STGFHSMKVKVMTEATKVIDLENNLFRENSTTEIAHQGLDCDEEEECNDHIQRMNFVCSQ 283
           S+  HS K+    +  K+ D  +NL R N    I++ G    + +EC    Q ++F+   
Sbjct: 136 SSTTHS-KIFQYNKYVKIFDNFSNLHRRN----ISNTGEKPFKCQECGKSFQMLSFLTEH 190

Query: 284 QSSECSRKKRKVSEPVKVFI 303
           Q     +K +K  E  K FI
Sbjct: 191 QKIHTGKKFQKCGECGKTFI 210


>gi|238624099 SET domain, bifurcated 2 isoform b [Homo sapiens]
          Length = 707

 Score = 28.9 bits (63), Expect = 6.0
 Identities = 11/36 (30%), Positives = 20/36 (55%)

Query: 88  QGCFDALEKRYLRMAVLTLYTDPMGSEKVTEMYQFK 123
           +GC D  +   L++      T P+ S+K+T  Y++K
Sbjct: 285 EGCIDITKCACLQLTARNAKTSPLSSDKITTGYKYK 320


>gi|238624095 SET domain, bifurcated 2 isoform a [Homo sapiens]
          Length = 719

 Score = 28.9 bits (63), Expect = 6.0
 Identities = 11/36 (30%), Positives = 20/36 (55%)

Query: 88  QGCFDALEKRYLRMAVLTLYTDPMGSEKVTEMYQFK 123
           +GC D  +   L++      T P+ S+K+T  Y++K
Sbjct: 297 EGCIDITKCACLQLTARNAKTSPLSSDKITTGYKYK 332


>gi|20070228 nucleobindin 1 [Homo sapiens]
          Length = 461

 Score = 28.5 bits (62), Expect = 7.8
 Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 6/80 (7%)

Query: 97  RYLRMAVLTLYTDPMGSEKVTEMYQFKFKYTKEGATMDFDSHSSSTSFESGTNNEDIKKA 156
           RYL+  +  L TD    EK+        K  K    +DF SH   T        +++K+ 
Sbjct: 53  RYLQEVIDVLETDGHFREKLQAANAEDIKSGKLSRELDFVSHHVRTKL------DELKRQ 106

Query: 157 SVLLIRKLYILMQDLEPLPN 176
            V  +R L     D E  PN
Sbjct: 107 EVSRLRMLLKAKMDAEQDPN 126


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,211,067
Number of Sequences: 37866
Number of extensions: 482467
Number of successful extensions: 1229
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1220
Number of HSP's gapped (non-prelim): 11
length of query: 307
length of database: 18,247,518
effective HSP length: 102
effective length of query: 205
effective length of database: 14,385,186
effective search space: 2948963130
effective search space used: 2948963130
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.