Search of human proteins with 22748937

Search of human proteins with 22748937

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22748937 exportin 5 [Homo sapiens]
         (1204 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22748937 exportin 5 [Homo sapiens]                                2407   0.0  
gi|4507943 exportin 1 [Homo sapiens]                                   73   1e-12
gi|8051636 tRNA exportin [Homo sapiens]                                69   4e-11
gi|29029559 CSE1 chromosome segregation 1-like protein [Homo sap...    40   0.017
gi|21361659 importin 9 [Homo sapiens]                                  32   2.8  
gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo sa...    31   8.1  
gi|75750468 spectrin domain with coiled-coils 1 NSP5a3a [Homo sa...    31   8.1  
gi|75750472 spectrin domain with coiled-coils 1 NSP5b3b [Homo sa...    31   8.1  
gi|75750466 spectrin domain with coiled-coils 1 NSP5b3a [Homo sa...    31   8.1  
gi|62526031 neurochondrin isoform 2 [Homo sapiens]                     31   8.1  
gi|24307949 neurochondrin isoform 1 [Homo sapiens]                     31   8.1  
gi|62526029 neurochondrin isoform 1 [Homo sapiens]                     31   8.1  

>gi|22748937 exportin 5 [Homo sapiens]
          Length = 1204

 Score = 2407 bits (6237), Expect = 0.0
 Identities = 1204/1204 (100%), Positives = 1204/1204 (100%)

Query: 1    MAMDQVNALCEQLVKAVTVMMDPNSTQRYRLEALKFCEEFKEKCPICVPCGLRLAEKTQV 60
            MAMDQVNALCEQLVKAVTVMMDPNSTQRYRLEALKFCEEFKEKCPICVPCGLRLAEKTQV
Sbjct: 1    MAMDQVNALCEQLVKAVTVMMDPNSTQRYRLEALKFCEEFKEKCPICVPCGLRLAEKTQV 60

Query: 61   AIVRHFGLQILEHVVKFRWNGMSRLEKVYLKNSVMELIANGTLNILEEENHIKDALSRIV 120
            AIVRHFGLQILEHVVKFRWNGMSRLEKVYLKNSVMELIANGTLNILEEENHIKDALSRIV
Sbjct: 61   AIVRHFGLQILEHVVKFRWNGMSRLEKVYLKNSVMELIANGTLNILEEENHIKDALSRIV 120

Query: 121  VEMIKREWPQHWPDMLIELDTLSKQGETQTELVMFILLRLAEDVVTFQTLPPQRRRDIQQ 180
            VEMIKREWPQHWPDMLIELDTLSKQGETQTELVMFILLRLAEDVVTFQTLPPQRRRDIQQ
Sbjct: 121  VEMIKREWPQHWPDMLIELDTLSKQGETQTELVMFILLRLAEDVVTFQTLPPQRRRDIQQ 180

Query: 181  TLTQNMERIFSFLLNTLQENVNKYQQVKTDTSQESKAQANCRVGVAALNTLAGYIDWVSM 240
            TLTQNMERIFSFLLNTLQENVNKYQQVKTDTSQESKAQANCRVGVAALNTLAGYIDWVSM
Sbjct: 181  TLTQNMERIFSFLLNTLQENVNKYQQVKTDTSQESKAQANCRVGVAALNTLAGYIDWVSM 240

Query: 241  SHITAENCKLLEILCLLLNEQELQLGAAECLLIAVSRKGKLEDRKPLMVLFGDVAMHYIL 300
            SHITAENCKLLEILCLLLNEQELQLGAAECLLIAVSRKGKLEDRKPLMVLFGDVAMHYIL
Sbjct: 241  SHITAENCKLLEILCLLLNEQELQLGAAECLLIAVSRKGKLEDRKPLMVLFGDVAMHYIL 300

Query: 301  SAAQTADGGGLVEKHYVFLKRLCQVLCALGNQLCALLGADSDVETPSNFGKYLESFLAFT 360
            SAAQTADGGGLVEKHYVFLKRLCQVLCALGNQLCALLGADSDVETPSNFGKYLESFLAFT
Sbjct: 301  SAAQTADGGGLVEKHYVFLKRLCQVLCALGNQLCALLGADSDVETPSNFGKYLESFLAFT 360

Query: 361  THPSQFLRSSTQMTWGALFRHEILSRDPLLLAIIPKYLRASMTNLVKMGFPSKTDSPSCE 420
            THPSQFLRSSTQMTWGALFRHEILSRDPLLLAIIPKYLRASMTNLVKMGFPSKTDSPSCE
Sbjct: 361  THPSQFLRSSTQMTWGALFRHEILSRDPLLLAIIPKYLRASMTNLVKMGFPSKTDSPSCE 420

Query: 421  YSRFDFDSDEDFNAFFNSSRAQQGEVMRLACRLDPKTSFQMAGEWLKYQLSTFLDAGSVN 480
            YSRFDFDSDEDFNAFFNSSRAQQGEVMRLACRLDPKTSFQMAGEWLKYQLSTFLDAGSVN
Sbjct: 421  YSRFDFDSDEDFNAFFNSSRAQQGEVMRLACRLDPKTSFQMAGEWLKYQLSTFLDAGSVN 480

Query: 481  SCSAVGTGEGSLCSVFSPSFVQWEAMTLFLESVITQMFRTLNREEIPVNDGIELLQMVLN 540
            SCSAVGTGEGSLCSVFSPSFVQWEAMTLFLESVITQMFRTLNREEIPVNDGIELLQMVLN
Sbjct: 481  SCSAVGTGEGSLCSVFSPSFVQWEAMTLFLESVITQMFRTLNREEIPVNDGIELLQMVLN 540

Query: 541  FDTKDPLILSCVLTNVSALFPFVTYRPEFLPQVFSKLFSSVTFETVEESKAPRTRAVRNV 600
            FDTKDPLILSCVLTNVSALFPFVTYRPEFLPQVFSKLFSSVTFETVEESKAPRTRAVRNV
Sbjct: 541  FDTKDPLILSCVLTNVSALFPFVTYRPEFLPQVFSKLFSSVTFETVEESKAPRTRAVRNV 600

Query: 601  RRHACSSIIKMCRDYPQLVLPNFDMLYNHVKQLLSNELLLTQMEKCALMEALVLISNQFK 660
            RRHACSSIIKMCRDYPQLVLPNFDMLYNHVKQLLSNELLLTQMEKCALMEALVLISNQFK
Sbjct: 601  RRHACSSIIKMCRDYPQLVLPNFDMLYNHVKQLLSNELLLTQMEKCALMEALVLISNQFK 660

Query: 661  NYERQKVFLEELMAPVASIWLSQDMHRVLSDVDAFIAYVGTDQKSCDPGLEDPCGLNRAR 720
            NYERQKVFLEELMAPVASIWLSQDMHRVLSDVDAFIAYVGTDQKSCDPGLEDPCGLNRAR
Sbjct: 661  NYERQKVFLEELMAPVASIWLSQDMHRVLSDVDAFIAYVGTDQKSCDPGLEDPCGLNRAR 720

Query: 721  MSFCVYSILGVVKRTCWPTDLEEAKAGGFVVGYTSSGNPIFRNPCTEQILKLLDNLLALI 780
            MSFCVYSILGVVKRTCWPTDLEEAKAGGFVVGYTSSGNPIFRNPCTEQILKLLDNLLALI
Sbjct: 721  MSFCVYSILGVVKRTCWPTDLEEAKAGGFVVGYTSSGNPIFRNPCTEQILKLLDNLLALI 780

Query: 781  RTHNTLYAPEMLAKMAEPFTKALDMLDAEKSAILGLPQPLLELNDSPVFKTVLERMQRFF 840
            RTHNTLYAPEMLAKMAEPFTKALDMLDAEKSAILGLPQPLLELNDSPVFKTVLERMQRFF
Sbjct: 781  RTHNTLYAPEMLAKMAEPFTKALDMLDAEKSAILGLPQPLLELNDSPVFKTVLERMQRFF 840

Query: 841  STLYENCFHILGKAGPSMQQDFYTVEDLATQLLSSAFVNLNNIPDYRLRPMLRVFVKPLV 900
            STLYENCFHILGKAGPSMQQDFYTVEDLATQLLSSAFVNLNNIPDYRLRPMLRVFVKPLV
Sbjct: 841  STLYENCFHILGKAGPSMQQDFYTVEDLATQLLSSAFVNLNNIPDYRLRPMLRVFVKPLV 900

Query: 901  LFCPPEHYEALVSPILGPLFTYLHMRLSQKWQVINQRSLLCGEDEAADENPESQEMLEEQ 960
            LFCPPEHYEALVSPILGPLFTYLHMRLSQKWQVINQRSLLCGEDEAADENPESQEMLEEQ
Sbjct: 901  LFCPPEHYEALVSPILGPLFTYLHMRLSQKWQVINQRSLLCGEDEAADENPESQEMLEEQ 960

Query: 961  LVRMLTREVMDLITVCCVSKKGADHSSAPPADGDDEEMMATEVTPSAMAELTDLGKCLMK 1020
            LVRMLTREVMDLITVCCVSKKGADHSSAPPADGDDEEMMATEVTPSAMAELTDLGKCLMK
Sbjct: 961  LVRMLTREVMDLITVCCVSKKGADHSSAPPADGDDEEMMATEVTPSAMAELTDLGKCLMK 1020

Query: 1021 HEDVCTALLITAFNSLAWKDTLSCQRTTSQLCWPLLKQVLSGTLLADAVTWLFTSVLKGL 1080
            HEDVCTALLITAFNSLAWKDTLSCQRTTSQLCWPLLKQVLSGTLLADAVTWLFTSVLKGL
Sbjct: 1021 HEDVCTALLITAFNSLAWKDTLSCQRTTSQLCWPLLKQVLSGTLLADAVTWLFTSVLKGL 1080

Query: 1081 QMHGQHDGCMASLVHLAFQIYEALRPRYLEIRAVMEQIPEIQKDSLDQFDCKLLNPSLQK 1140
            QMHGQHDGCMASLVHLAFQIYEALRPRYLEIRAVMEQIPEIQKDSLDQFDCKLLNPSLQK
Sbjct: 1081 QMHGQHDGCMASLVHLAFQIYEALRPRYLEIRAVMEQIPEIQKDSLDQFDCKLLNPSLQK 1140

Query: 1141 VADKRRKDQFKRLIAGCIGKPLGEQFRKEVHIKNLPSLFKKTKPMLETEVLDNDGGGLAT 1200
            VADKRRKDQFKRLIAGCIGKPLGEQFRKEVHIKNLPSLFKKTKPMLETEVLDNDGGGLAT
Sbjct: 1141 VADKRRKDQFKRLIAGCIGKPLGEQFRKEVHIKNLPSLFKKTKPMLETEVLDNDGGGLAT 1200

Query: 1201 IFEP 1204
            IFEP
Sbjct: 1201 IFEP 1204


>gi|4507943 exportin 1 [Homo sapiens]
          Length = 1071

 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 50/194 (25%), Positives = 97/194 (50%), Gaps = 22/194 (11%)

Query: 54  LAEKTQVAIVRHFGLQILEHVVKFRWNGMSRLEKVYLKNSVMELIANGTLN--ILEEENH 111
           + E +Q    +++GLQILE+V+K RW  + R +   +K  V+ LI   + +   +E+E  
Sbjct: 66  ILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCVEKEKV 125

Query: 112 IKDALSRIVVEMIKREWPQHWPDMLIELDTLSKQGETQTELVMFILLRLAEDVVTFQT-- 169
               L+ I+V+++K+EWP+HWP  + ++   S+  E+  +  M IL  L+E+V  F +  
Sbjct: 126 YIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFDFSSGQ 185

Query: 170 LPPQRRRDIQQTLTQNMERIFSFLLNTLQENVNKYQQVKTDTSQESKAQANCRVGVAALN 229
           +   + + ++ ++     +IF  L   + EN                   N  +  A L 
Sbjct: 186 ITQVKSKHLKDSMCNEFSQIFQ-LCQFVMEN-----------------SQNAPLVHATLE 227

Query: 230 TLAGYIDWVSMSHI 243
           TL  +++W+ + +I
Sbjct: 228 TLLRFLNWIPLGYI 241


>gi|8051636 tRNA exportin [Homo sapiens]
          Length = 962

 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 144/726 (19%), Positives = 283/726 (38%), Gaps = 124/726 (17%)

Query: 21  MDPNSTQRYRLEALKFCEEFKEKCPICVPCGLRLAEKTQVAI-VRHFGLQILEHVVKFRW 79
           ++PN+   +R  AL + E+ K        C   LA++T     V+ F  Q+LEH VK+++
Sbjct: 9   LNPNADSDFRQRALAYFEQLKISPDAWQVCAEALAQRTYSDDHVKFFCFQVLEHQVKYKY 68

Query: 80  NGMSRLEKVYLKNSVMELIANGTLNILEEENHIKDALSRIVVEMIKREWPQHWPDMLIEL 139
           + ++ +++  ++ +++  +    LN   E+  I++  +++   +   E+   WP    ++
Sbjct: 69  SELTTVQQQLIRETLISWLQAQMLNPQPEKTFIRNKAAQVFALLFVTEYLTKWPKFFFDI 128

Query: 140 DTLSKQGETQTELVMFILLRLAEDVVTFQTLPPQRRRDIQQTLTQNMERIFSFLLNTLQE 199
            ++        +L + IL+ +  ++V          RD+  T  +   R  + + +T++E
Sbjct: 129 LSVVDLNPRGVDLYLRILMAIDSELVD---------RDVVHTSEE--ARRNTLIKDTMRE 177

Query: 200 N-----VNKYQQVKTDTSQESKAQANCRVGVAALNTLAGYIDWVSMSHITAENCKLLEIL 254
                 V  + Q+     Q + ++  C+     L  +  Y+ W+ +S I   N + + +L
Sbjct: 178 QCIPNLVESWYQI-LQNYQFTNSEVTCQ----CLEVVGAYVSWIDLSLIA--NDRFINML 230

Query: 255 CLLLNEQELQLGAAECLLIAVSRKGKLEDRKPLMVLFGDVAMHYILSAAQTADGGGLVEK 314
              ++ + L+  A +CL   V++     D+  L                           
Sbjct: 231 LGHMSIEVLREEACDCLFEVVNKGMDPVDKMKL--------------------------- 263

Query: 315 HYVFLKRLCQVLCALGNQLCALLGADSDVETPSNFGKYLESFLAFTTHPSQFLRSSTQMT 374
               ++ LCQVL + G      +  + DV+  + F K +             +  S  ++
Sbjct: 264 ----VESLCQVLQSAG---FFSIDQEEDVDFLARFSKLVNG-----------MGQSLIVS 305

Query: 375 WGALFRH-EILSRDPLLLAIIPKYLRASMTNLVKMGFPSKTDSPSCEYSRFDFDSDEDFN 433
           W  L ++ +I +    L AI  K   A M  L+      + D  S     F +D      
Sbjct: 306 WSKLIKNGDIKNAQEALQAIETKV--ALMLQLL----IHEDDDISSNIIGFCYDYLHILK 359

Query: 434 AFFNSSRAQQGEVMRLACRL------DPKTSFQMAGE----WLKY--QLSTFLDAGSVNS 481
                S  Q+  V  +   +      D + +F+  GE    +++Y  QL   LD  +  S
Sbjct: 360 QLTVLSDQQKANVEAIMLAVMKKLTYDEEYNFENEGEDEAMFVEYRKQLKLLLDRLAQVS 419

Query: 482 CSAVGTGEGSLCSVFSPSFVQWEAMTLFLESVITQMFRTLNREEIPVNDGIELLQMVLNF 541
              +     S+  VFS +   W+  T F+E  +      +  E +PV+ G      V   
Sbjct: 420 PELL---LASVRRVFSSTLQNWQT-TRFMEVEVAIRLLYMLAEALPVSHGAHFSGDVSKA 475

Query: 542 DTKDPLILSCVLTNVSALFPFVTYRPEFLPQVFSKLFSSVTFETVEESKAPRT------- 594
                ++ + V + VS+ +   +   EF    F  +     F TVE    P         
Sbjct: 476 SALQDMMRTLVTSGVSS-YQHTSVTLEF----FETVVRYEKFFTVEPQHIPCVLMAFLDH 530

Query: 595 RAVRN----VRRHACSSIIKMCRDYPQLVLPNFDMLYNHVKQLL-------SNELLLTQM 643
           R +R+    VR        +  +   + + P  + + N ++ LL        ++ LL+  
Sbjct: 531 RGLRHSSAKVRSRTAYLFSRFVKSLNKQMNPFIEDILNRIQDLLELSPPENGHQSLLSSD 590

Query: 644 EKCALME-ALVLISNQFKNYERQKVFLEELMAP--------VASIWLSQDMHRVLSDVDA 694
           ++  + E A VLI N     ER++  +  L+ P        +  + L+QD  R  S  D 
Sbjct: 591 DQLFIYETAGVLIVNSEYPAERKQALMRNLLTPLMEKFKILLEKLMLAQDEERQASLADC 650

Query: 695 FIAYVG 700
               VG
Sbjct: 651 LNHAVG 656


>gi|29029559 CSE1 chromosome segregation 1-like protein [Homo
           sapiens]
          Length = 971

 Score = 39.7 bits (91), Expect = 0.017
 Identities = 34/152 (22%), Positives = 69/152 (45%), Gaps = 17/152 (11%)

Query: 3   MDQVNALCEQLVKAVTVMMDPNSTQRYRLEALKFCEEFKEKCPICVPCGLRLAEKTQVAI 62
           M+  +A  + L + +   +DP+   R   E      E  +  P+ +   L L EK+Q  +
Sbjct: 1   MELSDANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNYPLLL---LTLLEKSQDNV 57

Query: 63  VRHFGLQILEHVVKFRW-------NGMSRLEKVYLKNSVMELIANGTLNILEEENHIKDA 115
           ++       ++ +K  W       N +   ++V +K +++ L+ +    I   +  + DA
Sbjct: 58  IKVCASVTFKNYIKRNWRIVEDEPNKICEADRVAIKANIVHLMLSSPEQI---QKQLSDA 114

Query: 116 LSRIVVEMIKREWPQHWPDMLIELDTLSKQGE 147
           +S I  E    ++PQ WPD+L E+    + G+
Sbjct: 115 ISIIGRE----DFPQKWPDLLTEMVNRFQSGD 142


>gi|21361659 importin 9 [Homo sapiens]
          Length = 1041

 Score = 32.3 bits (72), Expect = 2.8
 Identities = 34/140 (24%), Positives = 61/140 (43%), Gaps = 26/140 (18%)

Query: 9   LCEQLVKAVTVMMDP----NSTQRYRLEALKFCEEFKEKCPICVPCGLRLAEKT---QVA 61
           L E LV  +T ++ P     +    +++ L+  EEF          G+ LAE T   Q A
Sbjct: 21  LKEALVDTLTGILSPVQEVRAAAEEQIKVLEVTEEF----------GVHLAELTVDPQGA 70

Query: 62  I-VRHFGLQILEHVVKFRWNGMSRLEKV-----YLKNSVMELIANGTLNILEEENHIKDA 115
           + +R     IL+  V+  W   S   +        K  + EL+ NG   + E  + ++ +
Sbjct: 71  LAIRQLASVILKQYVETHWCAQSEKFRPPETTERAKIVIRELLPNG---LRESISKVRSS 127

Query: 116 LSRIVVEMIKREWPQHWPDM 135
           ++  V  +   +WP+ WP +
Sbjct: 128 VAYAVSAIAHWDWPEAWPQL 147


>gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo
           sapiens]
          Length = 987

 Score = 30.8 bits (68), Expect = 8.1
 Identities = 52/248 (20%), Positives = 102/248 (41%), Gaps = 37/248 (14%)

Query: 86  EKVYLKNSVMELIANGTLNILEEENHIKDALSRIVVEMIKREWPQHWPDMLIELDT---- 141
           EK+  + +++E   +      E+ +   + L  ++ E +K E P      +IEL+     
Sbjct: 332 EKLVDEKTILETSFHQHRERAEQLSQENEKLMNLLQERVKNEEPTTQEGKIIELEQKCTG 391

Query: 142 LSKQGETQTELVMFILLRLAEDVVTFQTLPPQRRRDIQQTLTQNMERIFSFLLNTLQENV 201
           + +QG  + E ++ I  +L        T   ++  +  Q   + ++R     L    E +
Sbjct: 392 ILEQGRFEREKLLNIQQQL--------TCSLRKVEEENQGALEMIKR-----LKEENEKL 438

Query: 202 NKYQQVKT-DTSQESKAQANCRVGVAALNTLAGYIDWVSMSHITAENCKLLEILCLLLNE 260
           N++ +++  + +  +K    CRV +  L    G +     SH+  E  K  E   +    
Sbjct: 439 NEFLELERHNNNMMAKTLEECRVTLEGLKMENGSLK----SHLQGEKQKATEASAVEQTA 494

Query: 261 QELQLGAAECLLIAVSRKGKLED-----RKPLMVLFGDVAMHYILSAAQTADGGGLVEKH 315
           +  ++   E L +A + K  LE      R+ L+   G++     L A         VEK 
Sbjct: 495 ESCEV--QEMLKVARAEKDLLELSCNELRQELLKANGEIKHVSSLLAK--------VEKD 544

Query: 316 YVFLKRLC 323
           Y +LK +C
Sbjct: 545 YSYLKEIC 552


>gi|75750468 spectrin domain with coiled-coils 1 NSP5a3a [Homo
           sapiens]
          Length = 709

 Score = 30.8 bits (68), Expect = 8.1
 Identities = 52/248 (20%), Positives = 102/248 (41%), Gaps = 37/248 (14%)

Query: 86  EKVYLKNSVMELIANGTLNILEEENHIKDALSRIVVEMIKREWPQHWPDMLIELDT---- 141
           EK+  + +++E   +      E+ +   + L  ++ E +K E P      +IEL+     
Sbjct: 332 EKLVDEKTILETSFHQHRERAEQLSQENEKLMNLLQERVKNEEPTTQEGKIIELEQKCTG 391

Query: 142 LSKQGETQTELVMFILLRLAEDVVTFQTLPPQRRRDIQQTLTQNMERIFSFLLNTLQENV 201
           + +QG  + E ++ I  +L        T   ++  +  Q   + ++R     L    E +
Sbjct: 392 ILEQGRFEREKLLNIQQQL--------TCSLRKVEEENQGALEMIKR-----LKEENEKL 438

Query: 202 NKYQQVKT-DTSQESKAQANCRVGVAALNTLAGYIDWVSMSHITAENCKLLEILCLLLNE 260
           N++ +++  + +  +K    CRV +  L    G +     SH+  E  K  E   +    
Sbjct: 439 NEFLELERHNNNMMAKTLEECRVTLEGLKMENGSLK----SHLQGEKQKATEASAVEQTA 494

Query: 261 QELQLGAAECLLIAVSRKGKLED-----RKPLMVLFGDVAMHYILSAAQTADGGGLVEKH 315
           +  ++   E L +A + K  LE      R+ L+   G++     L A         VEK 
Sbjct: 495 ESCEV--QEMLKVARAEKDLLELSCNELRQELLKANGEIKHVSSLLAK--------VEKD 544

Query: 316 YVFLKRLC 323
           Y +LK +C
Sbjct: 545 YSYLKEIC 552


>gi|75750472 spectrin domain with coiled-coils 1 NSP5b3b [Homo
           sapiens]
          Length = 1068

 Score = 30.8 bits (68), Expect = 8.1
 Identities = 52/248 (20%), Positives = 102/248 (41%), Gaps = 37/248 (14%)

Query: 86  EKVYLKNSVMELIANGTLNILEEENHIKDALSRIVVEMIKREWPQHWPDMLIELDT---- 141
           EK+  + +++E   +      E+ +   + L  ++ E +K E P      +IEL+     
Sbjct: 413 EKLVDEKTILETSFHQHRERAEQLSQENEKLMNLLQERVKNEEPTTQEGKIIELEQKCTG 472

Query: 142 LSKQGETQTELVMFILLRLAEDVVTFQTLPPQRRRDIQQTLTQNMERIFSFLLNTLQENV 201
           + +QG  + E ++ I  +L        T   ++  +  Q   + ++R     L    E +
Sbjct: 473 ILEQGRFEREKLLNIQQQL--------TCSLRKVEEENQGALEMIKR-----LKEENEKL 519

Query: 202 NKYQQVKT-DTSQESKAQANCRVGVAALNTLAGYIDWVSMSHITAENCKLLEILCLLLNE 260
           N++ +++  + +  +K    CRV +  L    G +     SH+  E  K  E   +    
Sbjct: 520 NEFLELERHNNNMMAKTLEECRVTLEGLKMENGSLK----SHLQGEKQKATEASAVEQTA 575

Query: 261 QELQLGAAECLLIAVSRKGKLED-----RKPLMVLFGDVAMHYILSAAQTADGGGLVEKH 315
           +  ++   E L +A + K  LE      R+ L+   G++     L A         VEK 
Sbjct: 576 ESCEV--QEMLKVARAEKDLLELSCNELRQELLKANGEIKHVSSLLAK--------VEKD 625

Query: 316 YVFLKRLC 323
           Y +LK +C
Sbjct: 626 YSYLKEIC 633


>gi|75750466 spectrin domain with coiled-coils 1 NSP5b3a [Homo
           sapiens]
          Length = 790

 Score = 30.8 bits (68), Expect = 8.1
 Identities = 52/248 (20%), Positives = 102/248 (41%), Gaps = 37/248 (14%)

Query: 86  EKVYLKNSVMELIANGTLNILEEENHIKDALSRIVVEMIKREWPQHWPDMLIELDT---- 141
           EK+  + +++E   +      E+ +   + L  ++ E +K E P      +IEL+     
Sbjct: 413 EKLVDEKTILETSFHQHRERAEQLSQENEKLMNLLQERVKNEEPTTQEGKIIELEQKCTG 472

Query: 142 LSKQGETQTELVMFILLRLAEDVVTFQTLPPQRRRDIQQTLTQNMERIFSFLLNTLQENV 201
           + +QG  + E ++ I  +L        T   ++  +  Q   + ++R     L    E +
Sbjct: 473 ILEQGRFEREKLLNIQQQL--------TCSLRKVEEENQGALEMIKR-----LKEENEKL 519

Query: 202 NKYQQVKT-DTSQESKAQANCRVGVAALNTLAGYIDWVSMSHITAENCKLLEILCLLLNE 260
           N++ +++  + +  +K    CRV +  L    G +     SH+  E  K  E   +    
Sbjct: 520 NEFLELERHNNNMMAKTLEECRVTLEGLKMENGSLK----SHLQGEKQKATEASAVEQTA 575

Query: 261 QELQLGAAECLLIAVSRKGKLED-----RKPLMVLFGDVAMHYILSAAQTADGGGLVEKH 315
           +  ++   E L +A + K  LE      R+ L+   G++     L A         VEK 
Sbjct: 576 ESCEV--QEMLKVARAEKDLLELSCNELRQELLKANGEIKHVSSLLAK--------VEKD 625

Query: 316 YVFLKRLC 323
           Y +LK +C
Sbjct: 626 YSYLKEIC 633


>gi|62526031 neurochondrin isoform 2 [Homo sapiens]
          Length = 712

 Score = 30.8 bits (68), Expect = 8.1
 Identities = 33/112 (29%), Positives = 51/112 (45%), Gaps = 12/112 (10%)

Query: 97  LIANGTLNILEEE--NH---IKDALSRIVVEMIKRE---WPQHWPDMLIELDTLSKQGET 148
           LIA GT++ L +    H      AL+ +V  +   E   W +  PD+L  L  LS+  + 
Sbjct: 155 LIAGGTVSALCQAYLGHGYGFDQALALLVGLLAAAETQCWKEAEPDLLAVLRGLSEDFQK 214

Query: 149 QTELVMFILLRLAEDVVTFQTLPPQRRRDIQQTLTQNMERIFSFLLNTLQEN 200
             +   F L +L    +   T+PP+  RD+Q  L     RI    L++ Q N
Sbjct: 215 AEDASKFELCQLLPLFLPPTTVPPECYRDLQAGLA----RILGSKLSSWQRN 262


>gi|24307949 neurochondrin isoform 1 [Homo sapiens]
          Length = 729

 Score = 30.8 bits (68), Expect = 8.1
 Identities = 33/112 (29%), Positives = 51/112 (45%), Gaps = 12/112 (10%)

Query: 97  LIANGTLNILEEE--NH---IKDALSRIVVEMIKRE---WPQHWPDMLIELDTLSKQGET 148
           LIA GT++ L +    H      AL+ +V  +   E   W +  PD+L  L  LS+  + 
Sbjct: 172 LIAGGTVSALCQAYLGHGYGFDQALALLVGLLAAAETQCWKEAEPDLLAVLRGLSEDFQK 231

Query: 149 QTELVMFILLRLAEDVVTFQTLPPQRRRDIQQTLTQNMERIFSFLLNTLQEN 200
             +   F L +L    +   T+PP+  RD+Q  L     RI    L++ Q N
Sbjct: 232 AEDASKFELCQLLPLFLPPTTVPPECYRDLQAGLA----RILGSKLSSWQRN 279


>gi|62526029 neurochondrin isoform 1 [Homo sapiens]
          Length = 729

 Score = 30.8 bits (68), Expect = 8.1
 Identities = 33/112 (29%), Positives = 51/112 (45%), Gaps = 12/112 (10%)

Query: 97  LIANGTLNILEEE--NH---IKDALSRIVVEMIKRE---WPQHWPDMLIELDTLSKQGET 148
           LIA GT++ L +    H      AL+ +V  +   E   W +  PD+L  L  LS+  + 
Sbjct: 172 LIAGGTVSALCQAYLGHGYGFDQALALLVGLLAAAETQCWKEAEPDLLAVLRGLSEDFQK 231

Query: 149 QTELVMFILLRLAEDVVTFQTLPPQRRRDIQQTLTQNMERIFSFLLNTLQEN 200
             +   F L +L    +   T+PP+  RD+Q  L     RI    L++ Q N
Sbjct: 232 AEDASKFELCQLLPLFLPPTTVPPECYRDLQAGLA----RILGSKLSSWQRN 279


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,248,686
Number of Sequences: 37866
Number of extensions: 1870515
Number of successful extensions: 4319
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 4311
Number of HSP's gapped (non-prelim): 16
length of query: 1204
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1090
effective length of database: 13,930,794
effective search space: 15184565460
effective search space used: 15184565460
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.