Search of human proteins with 226371727

Search of human proteins with 226371727

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226371727 glucose-fructose oxidoreductase domain containing
2 [Homo sapiens]
         (385 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226371727 glucose-fructose oxidoreductase domain containing 2...   766   0.0  
gi|9506675 glucose-fructose oxidoreductase domain containing 1 [...   510   e-145
gi|153792305 leucine rich repeat containing 58 [Homo sapiens]          31   2.1  
gi|38570135 mitogen-activated protein kinase kinase kinase kinas...    30   2.8  
gi|14589909 mitogen-activated protein kinase kinase kinase kinas...    30   2.8  
gi|22035600 mitogen-activated protein kinase kinase kinase kinas...    30   3.7  
gi|126091152 cubilin [Homo sapiens]                                    29   6.3  

>gi|226371727 glucose-fructose oxidoreductase domain containing 2
           [Homo sapiens]
          Length = 385

 Score =  766 bits (1978), Expect = 0.0
 Identities = 385/385 (100%), Positives = 385/385 (100%)

Query: 1   MKMLPGVGVFGTGSSARVLVPLLRAEGFTVEALWGKTEEEAKQLAEEMNIAFYTSRTDDI 60
           MKMLPGVGVFGTGSSARVLVPLLRAEGFTVEALWGKTEEEAKQLAEEMNIAFYTSRTDDI
Sbjct: 1   MKMLPGVGVFGTGSSARVLVPLLRAEGFTVEALWGKTEEEAKQLAEEMNIAFYTSRTDDI 60

Query: 61  LLHQDVDLVCISIPPPLTRQISVKALGIGKNVVCEKAATSVDAFRMVTASRYYPQLMSLV 120
           LLHQDVDLVCISIPPPLTRQISVKALGIGKNVVCEKAATSVDAFRMVTASRYYPQLMSLV
Sbjct: 61  LLHQDVDLVCISIPPPLTRQISVKALGIGKNVVCEKAATSVDAFRMVTASRYYPQLMSLV 120

Query: 121 GNVLRFLPAFVRMKQLISEHYVGAVMICDARIYSGSLLSPSYGWICDELMGGGGLHTMGT 180
           GNVLRFLPAFVRMKQLISEHYVGAVMICDARIYSGSLLSPSYGWICDELMGGGGLHTMGT
Sbjct: 121 GNVLRFLPAFVRMKQLISEHYVGAVMICDARIYSGSLLSPSYGWICDELMGGGGLHTMGT 180

Query: 181 YIVDLLTHLTGRRAEKVHGLLKTFVRQNAAIRGIRHVTSDDFCFFQMLMGGGVCSTVTLN 240
           YIVDLLTHLTGRRAEKVHGLLKTFVRQNAAIRGIRHVTSDDFCFFQMLMGGGVCSTVTLN
Sbjct: 181 YIVDLLTHLTGRRAEKVHGLLKTFVRQNAAIRGIRHVTSDDFCFFQMLMGGGVCSTVTLN 240

Query: 241 FNMPGAFVHEVMVVGSAGRLVARGADLYGQKNSATQEELLLRDSLAVGAGLPEQGPQDVP 300
           FNMPGAFVHEVMVVGSAGRLVARGADLYGQKNSATQEELLLRDSLAVGAGLPEQGPQDVP
Sbjct: 241 FNMPGAFVHEVMVVGSAGRLVARGADLYGQKNSATQEELLLRDSLAVGAGLPEQGPQDVP 300

Query: 301 LLYLKGMVYMVQALRQSFQGQGDRRTWDRTPVSMAASFEDGLYMQSVVDAIKRSSRSGEW 360
           LLYLKGMVYMVQALRQSFQGQGDRRTWDRTPVSMAASFEDGLYMQSVVDAIKRSSRSGEW
Sbjct: 301 LLYLKGMVYMVQALRQSFQGQGDRRTWDRTPVSMAASFEDGLYMQSVVDAIKRSSRSGEW 360

Query: 361 EAVEVLTEEPDTNQNLCEALQRNNL 385
           EAVEVLTEEPDTNQNLCEALQRNNL
Sbjct: 361 EAVEVLTEEPDTNQNLCEALQRNNL 385


>gi|9506675 glucose-fructose oxidoreductase domain containing 1
           [Homo sapiens]
          Length = 390

 Score =  510 bits (1314), Expect = e-145
 Identities = 241/386 (62%), Positives = 317/386 (82%), Gaps = 3/386 (0%)

Query: 3   MLPGVGVFGTGSSARVLVPLLRAEGFTVEALWGKTEEEAKQLAEEMNIAFYTSRTDDILL 62
           MLPGVGVFGT  +ARV++PLL+ EGF V+ALWG+T+EEA++LA+EM++ FYTSR D++LL
Sbjct: 1   MLPGVGVFGTSLTARVIIPLLKDEGFAVKALWGRTQEEAEELAKEMSVPFYTSRIDEVLL 60

Query: 63  HQDVDLVCISIPPPLTRQISVKALGIGKNVVCEKAATSVDAFRMVTASRYYPQLMSLVGN 122
           HQDVDLVCI++PPPLTRQI+VK LGIGKNV+C++ AT +DAFRM +A+ YYP+LMS++GN
Sbjct: 61  HQDVDLVCINLPPPLTRQIAVKTLGIGKNVICDRTATPLDAFRMTSAAHYYPKLMSIMGN 120

Query: 123 VLRFLPAFVRMKQLISEHYVGAVMICDARIYSGSLLSPSYGWICDELMGGGGLHTMGTYI 182
           VLRFLPAFVRMKQLI E YVG  ++C+ +++ GSLL   Y W CD+LMGGGGLH++GTYI
Sbjct: 121 VLRFLPAFVRMKQLIEEGYVGEPLVCEVQVHGGSLLGKKYNWSCDDLMGGGGLHSVGTYI 180

Query: 183 VDLLTHLTGRRAEKVHGLLKTFVRQNAAIRGIRHVTSDDFCFFQMLMGGGVCSTVTLNFN 242
           +DLLT LTG++A KVHGLLKTFV+Q   I+GIR +TSDDFC FQM++ GGVC TVTLNFN
Sbjct: 181 IDLLTFLTGQKAVKVHGLLKTFVKQTDHIKGIRQITSDDFCTFQMVLEGGVCCTVTLNFN 240

Query: 243 MPGAFVHEVMVVGSAGRLVARGADLYGQKNSATQEELLLRDSLAVGAG-LPEQGPQDVPL 301
           +PG F  +V VVGSAGRL+A G DLYGQ+NSA ++ELL++D+  V    LPE+   D+P 
Sbjct: 241 VPGEFKQDVTVVGSAGRLLAVGTDLYGQRNSAPEQELLVQDATPVSNSLLPEKAFSDIPS 300

Query: 302 LYLKGMVYMVQALRQSFQGQGDRRTWDRTPVSMAASFEDGLYMQSVVDAIKRSSRSGEWE 361
            YL+G + M+QA+RQ+FQ Q DRRTWD  P++MAA+F+D LY   VVD IKRSS++GEW+
Sbjct: 301 PYLRGTIKMMQAVRQAFQDQDDRRTWDGRPLTMAATFDDCLYALCVVDTIKRSSQTGEWQ 360

Query: 362 AVEVLTEEPDTNQN--LCEALQRNNL 385
            + ++TEEP+ +    + EA++R+ +
Sbjct: 361 NIAIMTEEPELSPAYLISEAMRRSRM 386


>gi|153792305 leucine rich repeat containing 58 [Homo sapiens]
          Length = 371

 Score = 30.8 bits (68), Expect = 2.1
 Identities = 32/114 (28%), Positives = 55/114 (48%), Gaps = 9/114 (7%)

Query: 115 QLMSLVGNVLRFLPAFVRMKQLISEHYVGAVMICDARIYSGSLLSPSYGWICDELMGG-- 172
           Q +SL GN L+ +PA +   Q +   Y+G   I +     G+L S +Y  +CD  +    
Sbjct: 146 QTLSLGGNQLQSIPAEIENLQSLECLYLGGNFIKEIPPELGNLPSLNYLVLCDNKIQSIP 205

Query: 173 ---GGLHTMGTYIV--DLLTHLTGRRAEKVHGLLKTFVRQN-AAIRGIRHVTSD 220
                LH++ +  +  +LLT+L       +H L +  +R N   +R +R +T D
Sbjct: 206 PQLSQLHSLRSLSLHNNLLTYLPREILNLIH-LEELSLRGNPLVVRFVRDLTYD 258


>gi|38570135 mitogen-activated protein kinase kinase kinase kinase 5
           [Homo sapiens]
          Length = 846

 Score = 30.4 bits (67), Expect = 2.8
 Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 8/48 (16%)

Query: 148 CDARIYSGSLLSPSYGWICDELMGGGGLHTMGTYIVDLLTHLTGRRAE 195
           C+   Y GS LS    WIC E  GGG L          + H+TG  +E
Sbjct: 75  CNIVAYFGSYLSREKLWICMEYCGGGSLQD--------IYHVTGPLSE 114


>gi|14589909 mitogen-activated protein kinase kinase kinase kinase 5
           [Homo sapiens]
          Length = 846

 Score = 30.4 bits (67), Expect = 2.8
 Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 8/48 (16%)

Query: 148 CDARIYSGSLLSPSYGWICDELMGGGGLHTMGTYIVDLLTHLTGRRAE 195
           C+   Y GS LS    WIC E  GGG L          + H+TG  +E
Sbjct: 75  CNIVAYFGSYLSREKLWICMEYCGGGSLQD--------IYHVTGPLSE 114


>gi|22035600 mitogen-activated protein kinase kinase kinase kinase 2
           [Homo sapiens]
          Length = 820

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 55/234 (23%), Positives = 82/234 (35%), Gaps = 34/234 (14%)

Query: 153 YSGSLLSPSYGWICDELMGGGGLHTMGTYIVDLLTHLTGRRAEKVHGLLKTFVRQNAAIR 212
           Y GS L     WIC E  GGG L          + H TG   E+    +        A++
Sbjct: 76  YIGSYLRNDRLWICMEFCGGGSLQE--------IYHATGPLEERQIAYV-----CREALK 122

Query: 213 GIRHVTSDDFCFFQMLMGGGVCSTVTLNFNMPGAFVHEVMVVGSAGRLVARGADLYGQKN 272
           G+ H+ S      + + G  +  T+  +  +    V   +    A R    G   +    
Sbjct: 123 GLHHLHSQG-KIHRDIKGANLLLTLQGDVKLADFGVSGELTASVAKRRSFIGTPYWMAPE 181

Query: 273 SATQEEL----LLRDSLAVGAGLPEQGPQDVPLLYLKGMVYMVQALRQSFQGQ--GDRRT 326
            A  E       L D  A+G    E G    PL +L  M  ++   + SFQ     D+  
Sbjct: 182 VAAVERKGGYNELCDVWALGITAIELGELQPPLFHLHPMRALMLMSKSSFQPPKLRDKTR 241

Query: 327 WDRTPVSMAASFEDGLYMQSVVDAIKRSSRSGEWEAVEVLTEEPDTNQNLCEAL 380
           W +       +F   L +    +  KR +        E L + P T Q L  AL
Sbjct: 242 WTQ-------NFHHFLKLALTKNPKKRPT-------AEKLLQHPFTTQQLPRAL 281


>gi|126091152 cubilin [Homo sapiens]
          Length = 3623

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 35/119 (29%), Positives = 43/119 (36%), Gaps = 24/119 (20%)

Query: 149 DARIYSGSLLSPSYGWICDELMGGGGLH----TMGTYIVDLLTHLTGRR-AEKVHGLLKT 203
           +  IYSG+ LS   G  C   MG    H    T G           G   A  VHG+ + 
Sbjct: 173 ECEIYSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICED 232

Query: 204 FVRQNAAIRGIRHV--------------TSD-DFCFFQMLMGGGVCSTVTLNFNMPGAF 247
            +R+ A       V              T D D C FQ     G CST+   FN  G+F
Sbjct: 233 LMREQAGEPKYSCVCDAGWMFSPNSPACTLDRDECSFQ----PGPCSTLVQCFNTQGSF 287


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,914,157
Number of Sequences: 37866
Number of extensions: 574877
Number of successful extensions: 1063
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1057
Number of HSP's gapped (non-prelim): 7
length of query: 385
length of database: 18,247,518
effective HSP length: 104
effective length of query: 281
effective length of database: 14,309,454
effective search space: 4020956574
effective search space used: 4020956574
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.