Search of human proteins with 11545863

Search of human proteins with 11545863

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11545863 methylcrotonoyl-Coenzyme A carboxylase 2 (beta)
[Homo sapiens]
         (563 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11545863 methylcrotonoyl-Coenzyme A carboxylase 2 (beta) [Hom...  1130   0.0  
gi|119943100 propionyl Coenzyme A carboxylase, beta polypeptide ...   226   4e-59
gi|134142062 acetyl-Coenzyme A carboxylase beta [Homo sapiens]         48   3e-05
gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo ...    45   1e-04
gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo ...    45   1e-04
gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo ...    45   1e-04
gi|38679967 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo ...    45   1e-04
gi|38679960 acetyl-Coenzyme A carboxylase alpha isoform 1 [Homo ...    45   1e-04
gi|157738609 HECT domain containing 3 [Homo sapiens]                   31   3.5  

>gi|11545863 methylcrotonoyl-Coenzyme A carboxylase 2 (beta) [Homo
           sapiens]
          Length = 563

 Score = 1130 bits (2923), Expect = 0.0
 Identities = 563/563 (100%), Positives = 563/563 (100%)

Query: 1   MWAVLRLALRPCARASPAGPRAYHGDSVASLGTQPDLGSALYQENYKQMKALVNQLHERV 60
           MWAVLRLALRPCARASPAGPRAYHGDSVASLGTQPDLGSALYQENYKQMKALVNQLHERV
Sbjct: 1   MWAVLRLALRPCARASPAGPRAYHGDSVASLGTQPDLGSALYQENYKQMKALVNQLHERV 60

Query: 61  EHIKLGGGEKARALHISRGKLLPRERIDNLIDPGSPFLELSQFAGYQLYDNEEVPGGGII 120
           EHIKLGGGEKARALHISRGKLLPRERIDNLIDPGSPFLELSQFAGYQLYDNEEVPGGGII
Sbjct: 61  EHIKLGGGEKARALHISRGKLLPRERIDNLIDPGSPFLELSQFAGYQLYDNEEVPGGGII 120

Query: 121 TGIGRVSGVECMIIANDATVKGGAYYPVTVKKQLRAQEIAMQNRLPCIYLVDSGGAYLPR 180
           TGIGRVSGVECMIIANDATVKGGAYYPVTVKKQLRAQEIAMQNRLPCIYLVDSGGAYLPR
Sbjct: 121 TGIGRVSGVECMIIANDATVKGGAYYPVTVKKQLRAQEIAMQNRLPCIYLVDSGGAYLPR 180

Query: 181 QADVFPDRDHFGRTFYNQAIMSSKNIAQIAVVMGSCTAGGAYVPAMADENIIVRKQGTIF 240
           QADVFPDRDHFGRTFYNQAIMSSKNIAQIAVVMGSCTAGGAYVPAMADENIIVRKQGTIF
Sbjct: 181 QADVFPDRDHFGRTFYNQAIMSSKNIAQIAVVMGSCTAGGAYVPAMADENIIVRKQGTIF 240

Query: 241 LAGPPLVKAATGEEVSAEDLGGADLHCRKSGVSDHWALDDHHALHLTRKVVRNLNYQKKL 300
           LAGPPLVKAATGEEVSAEDLGGADLHCRKSGVSDHWALDDHHALHLTRKVVRNLNYQKKL
Sbjct: 241 LAGPPLVKAATGEEVSAEDLGGADLHCRKSGVSDHWALDDHHALHLTRKVVRNLNYQKKL 300

Query: 301 DVTIEPSEEPLFPADELYGIVGANLKRSFDVREVIARIVDGSRFTEFKAFYGDTLVTGFA 360
           DVTIEPSEEPLFPADELYGIVGANLKRSFDVREVIARIVDGSRFTEFKAFYGDTLVTGFA
Sbjct: 301 DVTIEPSEEPLFPADELYGIVGANLKRSFDVREVIARIVDGSRFTEFKAFYGDTLVTGFA 360

Query: 361 RIFGYPVGIVGNNGVLFSESAKKGTHFVQLCCQRNIPLLFLQNITGFMVGREYEAEGIAK 420
           RIFGYPVGIVGNNGVLFSESAKKGTHFVQLCCQRNIPLLFLQNITGFMVGREYEAEGIAK
Sbjct: 361 RIFGYPVGIVGNNGVLFSESAKKGTHFVQLCCQRNIPLLFLQNITGFMVGREYEAEGIAK 420

Query: 421 DGAKMVAAVACAQVPKITLIIGGSYGAGNYGMCGRAYSPRFLYIWPNARISVMGGEQAAN 480
           DGAKMVAAVACAQVPKITLIIGGSYGAGNYGMCGRAYSPRFLYIWPNARISVMGGEQAAN
Sbjct: 421 DGAKMVAAVACAQVPKITLIIGGSYGAGNYGMCGRAYSPRFLYIWPNARISVMGGEQAAN 480

Query: 481 VLATITKDQRAREGKQFSSADEAALKEPIIKKFEEEGNPYYSSARVWDDGIIDPADTRLV 540
           VLATITKDQRAREGKQFSSADEAALKEPIIKKFEEEGNPYYSSARVWDDGIIDPADTRLV
Sbjct: 481 VLATITKDQRAREGKQFSSADEAALKEPIIKKFEEEGNPYYSSARVWDDGIIDPADTRLV 540

Query: 541 LGLSFSAALNAPIEKTDFGIFRM 563
           LGLSFSAALNAPIEKTDFGIFRM
Sbjct: 541 LGLSFSAALNAPIEKTDFGIFRM 563


>gi|119943100 propionyl Coenzyme A carboxylase, beta polypeptide
           [Homo sapiens]
          Length = 539

 Score =  226 bits (576), Expect = 4e-59
 Identities = 166/530 (31%), Positives = 260/530 (49%), Gaps = 43/530 (8%)

Query: 28  VASLGTQPDLGSALYQENYKQMKALVNQLHERVEHIK----LGGGEKARALHISRGKLLP 83
           VA++G +  + ++  +   + + +    ++ER+E+ +    LGGG++       RGKL  
Sbjct: 7   VAAVGARLSVLASGLRAAVRSLCSQATSVNERIENKRRTALLGGGQRRIDAQHKRGKLTA 66

Query: 84  RERIDNLIDPGSPFLELSQFAGYQLYD------NEEVPGGGIITGIGRVSGVECMIIAND 137
           RERI  L+DPGS F+E   F  ++  D        + PG  ++TG GR++G    + + D
Sbjct: 67  RERISLLLDPGS-FVESDMFVEHRCADFGMAADKNKFPGDSVVTGRGRINGRLVYVFSQD 125

Query: 138 ATVKGGAYYPVTVKKQLRAQEIAMQNRLPCIYLVDSGGAYLPRQADVFPD-RDHFGRTFY 196
            TV GG+      +K  +  + A+    P I L DSGGA +    +      D F R   
Sbjct: 126 FTVFGGSLSGAHAQKICKIMDQAITVGAPVIGLNDSGGARIQEGVESLAGYADIFLRN-- 183

Query: 197 NQAIMSSKNIAQIAVVMGSCTAGGAYVPAMADENIIVRKQGTIFLAGPPLVKAATGEEVS 256
              + +S  I QI+++MG C  G  Y PA+ D   +V+    +F+ GP +VK+ T E+V+
Sbjct: 184 ---VTASGVIPQISLIMGPCAGGAVYSPALTDFTFMVKDTSYLFITGPDVVKSVTNEDVT 240

Query: 257 AEDLGGADLHCRKSGVSDHWALDDHHALHLTRKVVRNLNYQKKLDVTIEPSEEP---LFP 313
            E+LGGA  H   SGV+     +D  AL   R     L    +    +    +P   L P
Sbjct: 241 QEELGGAKTHTTMSGVAHRAFENDVDALCNLRDFFNYLPLSSQDPAPVRECHDPSDRLVP 300

Query: 314 ADELYGIVGANLKRSFDVREVIARIVDGSRFTEFKAFYGDTLVTGFARIFGYPVGIVGN- 372
             EL  IV     +++++ ++I  +VD   F E    Y   ++ GFAR+ G  VGIVGN 
Sbjct: 301 --ELDTIVPLESTKAYNMVDIIHSVVDEREFFEIMPNYAKNIIVGFARMNGRTVGIVGNQ 358

Query: 373 ----NGVLFSESAKKGTHFVQLCCQRNIPLLFLQNITGFMVGREYEAEGIAKDGAKMVAA 428
               +G L   S+ KG  FV+ C   NIPL+   ++ GF+ G   E  GI + GAK++ A
Sbjct: 359 PKVASGCLDINSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTAQEYGGIIRHGAKLLYA 418

Query: 429 VACAQVPKITLIIGGSYGAGNYGMCGRAYSPRFLYIWPNARISVMGGEQAANVLATITKD 488
            A A VPK+T+I   +YG     M  +       Y WP A I+VMG + A  ++      
Sbjct: 419 FAEATVPKVTVITRKAYGGAYDVMSSKHLCGDTNYAWPTAEIAVMGAKGAVEIIF----- 473

Query: 489 QRAREGKQFSSADEAALKEPIIKKFEEEGNPYYSSARVWDDGIIDPADTR 538
            +  E  + + A+        I+KF    NP+ ++ R + D II P+ TR
Sbjct: 474 -KGHENVEAAQAE-------YIEKF---ANPFPAAVRGFVDDIIQPSSTR 512


>gi|134142062 acetyl-Coenzyme A carboxylase beta [Homo sapiens]
          Length = 2458

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 79/337 (23%), Positives = 125/337 (37%), Gaps = 65/337 (19%)

Query: 141  KGGAYYPVTVKKQLRAQEIAMQNRLPCIYLVDSGGAYLPRQADVFPDRDHFG-------R 193
            KG  Y  +T +   R   I+  N + C + ++ GG       D+    D  G        
Sbjct: 1857 KGFKYLYLTPQDYTR---ISSLNSVHCKH-IEEGGESRYMITDIIGKDDGLGVENLRGSG 1912

Query: 194  TFYNQAIMSSKNIAQIAVVMGSCTAGGAYVPAMADENIIVRKQGTIFLAGPPLVKAATGE 253
                ++ ++ + I  I++V       GAY+  +  + +I  +   I L G   +    G 
Sbjct: 1913 MIAGESSLAYEEIVTISLVTCRAIGIGAYLVRLG-QRVIQVENSHIILTGASALNKVLGR 1971

Query: 254  EV--SAEDLGGADLHCRKSGVSDHWALDDHHALHLTRKVVRNLNYQKK------------ 299
            EV  S   LGG  +    +GVS     DD   ++    ++  L+Y  K            
Sbjct: 1972 EVYTSNNQLGGVQI-MHYNGVSHITVPDDFEGVYT---ILEWLSYMPKDNHSPVPIITPT 2027

Query: 300  --LDVTIE--PSEEPLFPADELYGIVGANLKRSFDVREVIARIVDGSRFTEFKAFYGDTL 355
              +D  IE  PS  P  P   L G     LK ++      +   D   F E  A +  T+
Sbjct: 2028 DPIDREIEFLPSRAPYDPRWMLAGRPHPTLKGTWQ-----SGFFDHGSFKEIMAPWAQTV 2082

Query: 356  VTGFARIFGYPVGIVG--------------------------NNGVLFSESAKKGTHFVQ 389
            VTG AR+ G PVG++                              V F +SA K    V+
Sbjct: 2083 VTGRARLGGIPVGVIAVETRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVK 2142

Query: 390  LCCQRNIPLLFLQNITGFMVGREYEAEGIAKDGAKMV 426
               +  +PL+   N  GF  G +   + + K GA +V
Sbjct: 2143 DFNREKLPLMIFANWRGFSGGMKDMYDQVLKFGAYIV 2179



 Score = 33.5 bits (75), Expect = 0.53
 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 9/79 (11%)

Query: 107  QLYDNEEVPGGGIITGIG---------RVSGVECMIIANDATVKGGAYYPVTVKKQLRAQ 157
            QL +   +PGG  +  +             G + ++I ND T + G++ P      LRA 
Sbjct: 1755 QLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIGSFGPGEDLLYLRAS 1814

Query: 158  EIAMQNRLPCIYLVDSGGA 176
            E+A    +P IY+  + GA
Sbjct: 1815 EMARAEGIPKIYVAANSGA 1833


>gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo
            sapiens]
          Length = 2346

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 84/391 (21%), Positives = 146/391 (37%), Gaps = 60/391 (15%)

Query: 141  KGGAYYPVTVKKQLRAQEIAMQNRLPCIYLVDSGGA------YLPRQADVFPDRDHFGRT 194
            KG  Y  +T +   R   +   N + C ++ D G +       + ++  + P+       
Sbjct: 1746 KGYRYLYLTPQDYKRVSAL---NSVHCEHVEDEGESRYKITDIIGKEEGIGPENLRGSGM 1802

Query: 195  FYNQAIMSSKNIAQIAVVMGSCTAGGAYVPAMADENIIVRKQGTIFLAGPPLVKAATGEE 254
               ++ ++   I  I++V       GAY+  +    I V     I L G   +    G E
Sbjct: 1803 IAGESSLAYNEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLI-LTGAGALNKVLGRE 1861

Query: 255  V--SAEDLGGADLHCRKSGVSDHWALDDH-------HALHLTRKVVRN----LNYQKKLD 301
            V  S   LGG  +    +GV+     DD        H L    K V +    LN +  +D
Sbjct: 1862 VYTSNNQLGGIQI-MHNNGVTHCTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPID 1920

Query: 302  VTIE--PSEEPLFPADELYGIVGANLKRSFDVREVIARIVDGSRFTEFKAFYGDTLVTGF 359
              IE  P++ P  P   L G      K  +     ++   D   F+E    +  T+V G 
Sbjct: 1921 RIIEFVPTKTPYDPRWMLAGRPHPTQKGQW-----LSGFFDYGSFSEIMQPWAQTVVVGR 1975

Query: 360  ARIFGYPVGIVG--------------------------NNGVLFSESAKKGTHFVQLCCQ 393
            AR+ G PVG+V                              V F +SA K    ++   +
Sbjct: 1976 ARLGGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNR 2035

Query: 394  RNIPLLFLQNITGFMVGREYEAEGIAKDGAKMVAAV-ACAQVPKITLIIGGSYGAGNYGM 452
              +PL+   N  GF  G +   + + K GA +V  +  C Q   + +        G++ +
Sbjct: 2036 EGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECCQPVLVYIPPQAELRGGSWVV 2095

Query: 453  CGRAYSPRFLYIWPN--ARISVMGGEQAANV 481
               + +PR + ++ +  +R SV+  E    +
Sbjct: 2096 IDSSINPRHMEMYADRESRGSVLEPEGTVEI 2126



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 17/49 (34%), Positives = 27/49 (55%)

Query: 128  GVECMIIANDATVKGGAYYPVTVKKQLRAQEIAMQNRLPCIYLVDSGGA 176
            G + ++I ND T + G++ P      LRA E+A    +P IY+  + GA
Sbjct: 1674 GRDIIVIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVSANSGA 1722


>gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo
            sapiens]
          Length = 2268

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 84/391 (21%), Positives = 146/391 (37%), Gaps = 60/391 (15%)

Query: 141  KGGAYYPVTVKKQLRAQEIAMQNRLPCIYLVDSGGA------YLPRQADVFPDRDHFGRT 194
            KG  Y  +T +   R   +   N + C ++ D G +       + ++  + P+       
Sbjct: 1668 KGYRYLYLTPQDYKRVSAL---NSVHCEHVEDEGESRYKITDIIGKEEGIGPENLRGSGM 1724

Query: 195  FYNQAIMSSKNIAQIAVVMGSCTAGGAYVPAMADENIIVRKQGTIFLAGPPLVKAATGEE 254
               ++ ++   I  I++V       GAY+  +    I V     I L G   +    G E
Sbjct: 1725 IAGESSLAYNEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLI-LTGAGALNKVLGRE 1783

Query: 255  V--SAEDLGGADLHCRKSGVSDHWALDDH-------HALHLTRKVVRN----LNYQKKLD 301
            V  S   LGG  +    +GV+     DD        H L    K V +    LN +  +D
Sbjct: 1784 VYTSNNQLGGIQI-MHNNGVTHCTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPID 1842

Query: 302  VTIE--PSEEPLFPADELYGIVGANLKRSFDVREVIARIVDGSRFTEFKAFYGDTLVTGF 359
              IE  P++ P  P   L G      K  +     ++   D   F+E    +  T+V G 
Sbjct: 1843 RIIEFVPTKTPYDPRWMLAGRPHPTQKGQW-----LSGFFDYGSFSEIMQPWAQTVVVGR 1897

Query: 360  ARIFGYPVGIVG--------------------------NNGVLFSESAKKGTHFVQLCCQ 393
            AR+ G PVG+V                              V F +SA K    ++   +
Sbjct: 1898 ARLGGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNR 1957

Query: 394  RNIPLLFLQNITGFMVGREYEAEGIAKDGAKMVAAV-ACAQVPKITLIIGGSYGAGNYGM 452
              +PL+   N  GF  G +   + + K GA +V  +  C Q   + +        G++ +
Sbjct: 1958 EGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECCQPVLVYIPPQAELRGGSWVV 2017

Query: 453  CGRAYSPRFLYIWPN--ARISVMGGEQAANV 481
               + +PR + ++ +  +R SV+  E    +
Sbjct: 2018 IDSSINPRHMEMYADRESRGSVLEPEGTVEI 2048



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 17/49 (34%), Positives = 27/49 (55%)

Query: 128  GVECMIIANDATVKGGAYYPVTVKKQLRAQEIAMQNRLPCIYLVDSGGA 176
            G + ++I ND T + G++ P      LRA E+A    +P IY+  + GA
Sbjct: 1596 GRDIIVIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVSANSGA 1644


>gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo
            sapiens]
          Length = 2288

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 84/391 (21%), Positives = 146/391 (37%), Gaps = 60/391 (15%)

Query: 141  KGGAYYPVTVKKQLRAQEIAMQNRLPCIYLVDSGGA------YLPRQADVFPDRDHFGRT 194
            KG  Y  +T +   R   +   N + C ++ D G +       + ++  + P+       
Sbjct: 1688 KGYRYLYLTPQDYKRVSAL---NSVHCEHVEDEGESRYKITDIIGKEEGIGPENLRGSGM 1744

Query: 195  FYNQAIMSSKNIAQIAVVMGSCTAGGAYVPAMADENIIVRKQGTIFLAGPPLVKAATGEE 254
               ++ ++   I  I++V       GAY+  +    I V     I L G   +    G E
Sbjct: 1745 IAGESSLAYNEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLI-LTGAGALNKVLGRE 1803

Query: 255  V--SAEDLGGADLHCRKSGVSDHWALDDH-------HALHLTRKVVRN----LNYQKKLD 301
            V  S   LGG  +    +GV+     DD        H L    K V +    LN +  +D
Sbjct: 1804 VYTSNNQLGGIQI-MHNNGVTHCTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPID 1862

Query: 302  VTIE--PSEEPLFPADELYGIVGANLKRSFDVREVIARIVDGSRFTEFKAFYGDTLVTGF 359
              IE  P++ P  P   L G      K  +     ++   D   F+E    +  T+V G 
Sbjct: 1863 RIIEFVPTKTPYDPRWMLAGRPHPTQKGQW-----LSGFFDYGSFSEIMQPWAQTVVVGR 1917

Query: 360  ARIFGYPVGIVG--------------------------NNGVLFSESAKKGTHFVQLCCQ 393
            AR+ G PVG+V                              V F +SA K    ++   +
Sbjct: 1918 ARLGGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNR 1977

Query: 394  RNIPLLFLQNITGFMVGREYEAEGIAKDGAKMVAAV-ACAQVPKITLIIGGSYGAGNYGM 452
              +PL+   N  GF  G +   + + K GA +V  +  C Q   + +        G++ +
Sbjct: 1978 EGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECCQPVLVYIPPQAELRGGSWVV 2037

Query: 453  CGRAYSPRFLYIWPN--ARISVMGGEQAANV 481
               + +PR + ++ +  +R SV+  E    +
Sbjct: 2038 IDSSINPRHMEMYADRESRGSVLEPEGTVEI 2068



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 17/49 (34%), Positives = 27/49 (55%)

Query: 128  GVECMIIANDATVKGGAYYPVTVKKQLRAQEIAMQNRLPCIYLVDSGGA 176
            G + ++I ND T + G++ P      LRA E+A    +P IY+  + GA
Sbjct: 1616 GRDIIVIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVSANSGA 1664


>gi|38679967 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo
            sapiens]
          Length = 2346

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 84/391 (21%), Positives = 146/391 (37%), Gaps = 60/391 (15%)

Query: 141  KGGAYYPVTVKKQLRAQEIAMQNRLPCIYLVDSGGA------YLPRQADVFPDRDHFGRT 194
            KG  Y  +T +   R   +   N + C ++ D G +       + ++  + P+       
Sbjct: 1746 KGYRYLYLTPQDYKRVSAL---NSVHCEHVEDEGESRYKITDIIGKEEGIGPENLRGSGM 1802

Query: 195  FYNQAIMSSKNIAQIAVVMGSCTAGGAYVPAMADENIIVRKQGTIFLAGPPLVKAATGEE 254
               ++ ++   I  I++V       GAY+  +    I V     I L G   +    G E
Sbjct: 1803 IAGESSLAYNEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLI-LTGAGALNKVLGRE 1861

Query: 255  V--SAEDLGGADLHCRKSGVSDHWALDDH-------HALHLTRKVVRN----LNYQKKLD 301
            V  S   LGG  +    +GV+     DD        H L    K V +    LN +  +D
Sbjct: 1862 VYTSNNQLGGIQI-MHNNGVTHCTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPID 1920

Query: 302  VTIE--PSEEPLFPADELYGIVGANLKRSFDVREVIARIVDGSRFTEFKAFYGDTLVTGF 359
              IE  P++ P  P   L G      K  +     ++   D   F+E    +  T+V G 
Sbjct: 1921 RIIEFVPTKTPYDPRWMLAGRPHPTQKGQW-----LSGFFDYGSFSEIMQPWAQTVVVGR 1975

Query: 360  ARIFGYPVGIVG--------------------------NNGVLFSESAKKGTHFVQLCCQ 393
            AR+ G PVG+V                              V F +SA K    ++   +
Sbjct: 1976 ARLGGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNR 2035

Query: 394  RNIPLLFLQNITGFMVGREYEAEGIAKDGAKMVAAV-ACAQVPKITLIIGGSYGAGNYGM 452
              +PL+   N  GF  G +   + + K GA +V  +  C Q   + +        G++ +
Sbjct: 2036 EGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECCQPVLVYIPPQAELRGGSWVV 2095

Query: 453  CGRAYSPRFLYIWPN--ARISVMGGEQAANV 481
               + +PR + ++ +  +R SV+  E    +
Sbjct: 2096 IDSSINPRHMEMYADRESRGSVLEPEGTVEI 2126



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 17/49 (34%), Positives = 27/49 (55%)

Query: 128  GVECMIIANDATVKGGAYYPVTVKKQLRAQEIAMQNRLPCIYLVDSGGA 176
            G + ++I ND T + G++ P      LRA E+A    +P IY+  + GA
Sbjct: 1674 GRDIIVIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVSANSGA 1722


>gi|38679960 acetyl-Coenzyme A carboxylase alpha isoform 1 [Homo
            sapiens]
          Length = 2383

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 84/391 (21%), Positives = 146/391 (37%), Gaps = 60/391 (15%)

Query: 141  KGGAYYPVTVKKQLRAQEIAMQNRLPCIYLVDSGGA------YLPRQADVFPDRDHFGRT 194
            KG  Y  +T +   R   +   N + C ++ D G +       + ++  + P+       
Sbjct: 1783 KGYRYLYLTPQDYKRVSAL---NSVHCEHVEDEGESRYKITDIIGKEEGIGPENLRGSGM 1839

Query: 195  FYNQAIMSSKNIAQIAVVMGSCTAGGAYVPAMADENIIVRKQGTIFLAGPPLVKAATGEE 254
               ++ ++   I  I++V       GAY+  +    I V     I L G   +    G E
Sbjct: 1840 IAGESSLAYNEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLI-LTGAGALNKVLGRE 1898

Query: 255  V--SAEDLGGADLHCRKSGVSDHWALDDH-------HALHLTRKVVRN----LNYQKKLD 301
            V  S   LGG  +    +GV+     DD        H L    K V +    LN +  +D
Sbjct: 1899 VYTSNNQLGGIQI-MHNNGVTHCTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPID 1957

Query: 302  VTIE--PSEEPLFPADELYGIVGANLKRSFDVREVIARIVDGSRFTEFKAFYGDTLVTGF 359
              IE  P++ P  P   L G      K  +     ++   D   F+E    +  T+V G 
Sbjct: 1958 RIIEFVPTKTPYDPRWMLAGRPHPTQKGQW-----LSGFFDYGSFSEIMQPWAQTVVVGR 2012

Query: 360  ARIFGYPVGIVG--------------------------NNGVLFSESAKKGTHFVQLCCQ 393
            AR+ G PVG+V                              V F +SA K    ++   +
Sbjct: 2013 ARLGGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNR 2072

Query: 394  RNIPLLFLQNITGFMVGREYEAEGIAKDGAKMVAAV-ACAQVPKITLIIGGSYGAGNYGM 452
              +PL+   N  GF  G +   + + K GA +V  +  C Q   + +        G++ +
Sbjct: 2073 EGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECCQPVLVYIPPQAELRGGSWVV 2132

Query: 453  CGRAYSPRFLYIWPN--ARISVMGGEQAANV 481
               + +PR + ++ +  +R SV+  E    +
Sbjct: 2133 IDSSINPRHMEMYADRESRGSVLEPEGTVEI 2163



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 17/49 (34%), Positives = 27/49 (55%)

Query: 128  GVECMIIANDATVKGGAYYPVTVKKQLRAQEIAMQNRLPCIYLVDSGGA 176
            G + ++I ND T + G++ P      LRA E+A    +P IY+  + GA
Sbjct: 1711 GRDIIVIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVSANSGA 1759


>gi|157738609 HECT domain containing 3 [Homo sapiens]
          Length = 861

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 1/63 (1%)

Query: 270 SGVSDHWALDDHHALHLTRKVVRNLNYQKKLDVTIEPSEEPLFPAD-ELYGIVGANLKRS 328
           S    +W  D     H  R  ++     KKL +T++ +++   P    +YG  G NLK+ 
Sbjct: 264 SNADTYWESDGSQCQHWVRLTMKKGTIVKKLLLTVDTTDDNFMPKRVVVYGGEGDNLKKL 323

Query: 329 FDV 331
            DV
Sbjct: 324 SDV 326


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.138    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,089,287
Number of Sequences: 37866
Number of extensions: 932504
Number of successful extensions: 1975
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1946
Number of HSP's gapped (non-prelim): 22
length of query: 563
length of database: 18,247,518
effective HSP length: 107
effective length of query: 456
effective length of database: 14,195,856
effective search space: 6473310336
effective search space used: 6473310336
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.