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Search of human proteins with 224548987
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224548987 presenilin stabilization factor-like isoform 2
[Homo sapiens]
(216 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224548987 presenilin stabilization factor-like isoform 2 [Hom... 430 e-121
gi|50726954 presenilin stabilization factor-like isoform 1 [Homo... 410 e-115
gi|117606357 anterior pharynx defective 1 homolog A isoform 2 [H... 219 2e-57
gi|117606362 anterior pharynx defective 1 homolog A isoform 1 [H... 218 4e-57
gi|217330618 Sec61 alpha form 2 isoform b [Homo sapiens] 30 2.0
gi|217330616 Sec61 alpha form 2 isoform c [Homo sapiens] 30 2.0
gi|14589847 Sec61 alpha form 2 isoform a [Homo sapiens] 30 2.0
gi|48717231 olfactory receptor, family 9, subfamily A, member 4 ... 30 2.0
gi|181337167 solute carrier family 7 (cationic amino acid transp... 29 2.7
gi|4757708 acetyl-coenzyme A transporter [Homo sapiens] 28 4.5
gi|7019415 Sec61 alpha 1 subunit [Homo sapiens] 28 7.8
gi|4502067 alpha-1-microglobulin/bikunin preproprotein [Homo sap... 28 7.8
>gi|224548987 presenilin stabilization factor-like isoform 2 [Homo
sapiens]
Length = 216
Score = 430 bits (1105), Expect = e-121
Identities = 216/216 (100%), Positives = 216/216 (100%)
Query: 1 MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII 60
MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII
Sbjct: 1 MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII 60
Query: 61 DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAPSMRLLAYAF 120
DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAPSMRLLAYAF
Sbjct: 61 DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAPSMRLLAYAF 120
Query: 121 MTLVIILLHVFWGIVFFDGCEKKKWGILLIVLLTHLLVSAQTFISSYYGINLASAFIILV 180
MTLVIILLHVFWGIVFFDGCEKKKWGILLIVLLTHLLVSAQTFISSYYGINLASAFIILV
Sbjct: 121 MTLVIILLHVFWGIVFFDGCEKKKWGILLIVLLTHLLVSAQTFISSYYGINLASAFIILV 180
Query: 181 LMGTWAFLAAGGSCRSLKLCLLCQDKNFLLYNQRSR 216
LMGTWAFLAAGGSCRSLKLCLLCQDKNFLLYNQRSR
Sbjct: 181 LMGTWAFLAAGGSCRSLKLCLLCQDKNFLLYNQRSR 216
>gi|50726954 presenilin stabilization factor-like isoform 1 [Homo
sapiens]
Length = 257
Score = 410 bits (1053), Expect = e-115
Identities = 216/257 (84%), Positives = 216/257 (84%), Gaps = 41/257 (15%)
Query: 1 MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII 60
MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII
Sbjct: 1 MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII 60
Query: 61 DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAPSMRLLAY-- 118
DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAPSMRLLAY
Sbjct: 61 DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAPSMRLLAYVS 120
Query: 119 ---------------------------------------AFMTLVIILLHVFWGIVFFDG 139
AFMTLVIILLHVFWGIVFFDG
Sbjct: 121 GLGFGIMSGVFSFVNTLSDSLGPGTVGIHGDSPQFFLYSAFMTLVIILLHVFWGIVFFDG 180
Query: 140 CEKKKWGILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLKL 199
CEKKKWGILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLKL
Sbjct: 181 CEKKKWGILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLKL 240
Query: 200 CLLCQDKNFLLYNQRSR 216
CLLCQDKNFLLYNQRSR
Sbjct: 241 CLLCQDKNFLLYNQRSR 257
>gi|117606357 anterior pharynx defective 1 homolog A isoform 2 [Homo
sapiens]
Length = 247
Score = 219 bits (557), Expect = 2e-57
Identities = 116/247 (46%), Positives = 154/247 (62%), Gaps = 42/247 (17%)
Query: 1 MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII 60
M AAVFFGC F+AFGPA AL++ T+A +PLR+I L+AGAFFWLVSLL++S+VWF+ +
Sbjct: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
Query: 61 DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAP-SMRLLAY- 118
D D Q LLIFGA VSV +QE+FRFAYYKLLKKA EGL S++ +P S+R +AY
Sbjct: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
Query: 119 ----------------------------------------AFMTLVIILLHVFWGIVFFD 138
AF+T IILLH FWG+VFFD
Sbjct: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
Query: 139 GCEKKKWGILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLK 198
CE++++ L +V+ +HLL S TF++ +Y +L + + V MG WAF+ AGGS RS++
Sbjct: 181 ACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQ 240
Query: 199 LCLLCQD 205
LLC+D
Sbjct: 241 RSLLCKD 247
>gi|117606362 anterior pharynx defective 1 homolog A isoform 1 [Homo
sapiens]
Length = 265
Score = 218 bits (554), Expect = 4e-57
Identities = 117/257 (45%), Positives = 158/257 (61%), Gaps = 45/257 (17%)
Query: 1 MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII 60
M AAVFFGC F+AFGPA AL++ T+A +PLR+I L+AGAFFWLVSLL++S+VWF+ +
Sbjct: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
Query: 61 DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAP-SMRLLAY- 118
D D Q LLIFGA VSV +QE+FRFAYYKLLKKA EGL S++ +P S+R +AY
Sbjct: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
Query: 119 ----------------------------------------AFMTLVIILLHVFWGIVFFD 138
AF+T IILLH FWG+VFFD
Sbjct: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
Query: 139 GCEKKKWGILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLK 198
CE++++ L +V+ +HLL S TF++ +Y +L + + V MG WAF+ AGGS RS++
Sbjct: 181 ACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQ 240
Query: 199 LCLLC---QDKNFLLYN 212
LLC +D ++Y+
Sbjct: 241 RSLLCRRQEDSRVMVYS 257
>gi|217330618 Sec61 alpha form 2 isoform b [Homo sapiens]
Length = 454
Score = 29.6 bits (65), Expect = 2.0
Identities = 17/53 (32%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Query: 151 VLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLKLCLLC 203
++L LVS IS + + F++ L+G WA ++ GG RS + LC
Sbjct: 269 IILQSALVSNLYVISQMLSVRFSGNFLVN-LLGQWADVSGGGPARSYPVGGLC 320
>gi|217330616 Sec61 alpha form 2 isoform c [Homo sapiens]
Length = 437
Score = 29.6 bits (65), Expect = 2.0
Identities = 17/53 (32%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Query: 151 VLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLKLCLLC 203
++L LVS IS + + F++ L+G WA ++ GG RS + LC
Sbjct: 291 IILQSALVSNLYVISQMLSVRFSGNFLVN-LLGQWADVSGGGPARSYPVGGLC 342
>gi|14589847 Sec61 alpha form 2 isoform a [Homo sapiens]
Length = 476
Score = 29.6 bits (65), Expect = 2.0
Identities = 17/53 (32%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Query: 151 VLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLKLCLLC 203
++L LVS IS + + F++ L+G WA ++ GG RS + LC
Sbjct: 291 IILQSALVSNLYVISQMLSVRFSGNFLVN-LLGQWADVSGGGPARSYPVGGLC 342
>gi|48717231 olfactory receptor, family 9, subfamily A, member 4
[Homo sapiens]
Length = 314
Score = 29.6 bits (65), Expect = 2.0
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 8/54 (14%)
Query: 2 TAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFM 55
T A F C I +G L LYV T+ A + W+VSL++S + F+
Sbjct: 240 TCASHFTCVVIGYGSCLFLYVKPKQTQ--------AADYNWVVSLMVSVVTPFL 285
>gi|181337167 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 14 [Homo sapiens]
Length = 771
Score = 29.3 bits (64), Expect = 2.7
Identities = 14/44 (31%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
Query: 123 LVIILLHVFWGIVFF--DGCEKKKWGILLIVLLTHLLVSAQTFI 164
L+ IL+ +F + F D ++ W +L+V+L LL+S F+
Sbjct: 571 LLFILMFIFCSFIIFGSDYISEQSWWAILLVVLMVLLISTLVFV 614
>gi|4757708 acetyl-coenzyme A transporter [Homo sapiens]
Length = 549
Score = 28.5 bits (62), Expect = 4.5
Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 16/113 (14%)
Query: 28 EPLRIIFLIAGAFFW-LVSLLISSLVWFMAR-----VIIDNKDGPTQKYLLIFGAFVSVY 81
+P I+ L FFW V L+ ++LV + + V+ + G T Y L+F +
Sbjct: 250 QPRGIVTLSDFLFFWGTVFLITTTLVALLKKENEVSVVKEETQGITDTYKLLFAI---IK 306
Query: 82 IQEMFRFAYYKLLKK-------ASEGLKSINPGETAPSMRLLAYAFMTLVIIL 127
+ + F L K A GLK + G + LLA + L IIL
Sbjct: 307 MPAVLTFCLLILTAKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIIL 359
>gi|7019415 Sec61 alpha 1 subunit [Homo sapiens]
Length = 476
Score = 27.7 bits (60), Expect = 7.8
Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 6/57 (10%)
Query: 147 ILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLKLCLLC 203
IL L+++L V +Q + + G L S L+GTW+ ++GG R+ + LC
Sbjct: 292 ILQSALVSNLYVISQMLSARFSGNLLVS------LLGTWSDTSSGGPARAYPVGGLC 342
>gi|4502067 alpha-1-microglobulin/bikunin preproprotein [Homo
sapiens]
Length = 352
Score = 27.7 bits (60), Expect = 7.8
Identities = 19/53 (35%), Positives = 25/53 (47%)
Query: 146 GILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLK 198
G LL++L L VSA + I + F I + G W LA G +C LK
Sbjct: 5 GALLLLLSACLAVSAGPVPTPPDNIQVQENFNISRIYGKWYNLAIGSTCPWLK 57
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.334 0.145 0.456
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,069,419
Number of Sequences: 37866
Number of extensions: 253140
Number of successful extensions: 1016
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1007
Number of HSP's gapped (non-prelim): 15
length of query: 216
length of database: 18,247,518
effective HSP length: 98
effective length of query: 118
effective length of database: 14,536,650
effective search space: 1715324700
effective search space used: 1715324700
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 39 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.